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Proceedings Of The 2nd Annual Cuny Games Festival, Robert O. Duncan, Joe Bisz, Francesco Crocco, Carlos Hernandez, Kathleen Offenholley, Maura A. Smale, Deborah Sturm, Cuny Games Network

Publications and Research

Proceedings of the CUNY Games Conference, held from January 16-17, 2015, at the CUNY Graduate Center and Borough of Manhattan Community College.

Health Games - Language and Composition - Design: Classroom Considerations - Games in the Physical Environment - Games and Behavioral Science - Play, Politics & Economics - Gaming Curricula, Disciplines & Programs - Gaming and History - Institutional Programming with Games - Philosophy and Roleplaying - Ed. Game Design: Strategy & Tactics - Repurposing Game Genres - Narrative, Storytelling & Games - Community & Social Justice - Extemporaneity - Personal & Social Transformation - Cognition, Design & Play …

Linking The Effects Of Risk Factors On Annual Calf Survival To Elk Population Dynamics In The Bitterroot Valley, Montana, Daniel R. Eacker

Graduate Student Theses, Dissertations, & Professional Papers

The recolonization of gray wolves (Canis lupus) in multiple carnivore systems has been correlated with declining recruitment of juvenile ungulates, but the importance of wolves relative to other established carnivores is uncertain. The realized effect of carnivores may depend on compensation from forage and winter weather severity, which may mediate juvenile vulnerability to predation. Also, in high predation systems, the importance of juvenile recruitment may be reduced for ungulate population dynamics. We first tested for the effects of risk factors on annual elk (Cervus elaphus) calf survival and estimated cause-specific mortality rates. Secondly, we investigated the …

From Lazarus To Theophilus: How Manuscript Digitization Led To The Historical, Chemical, And Technological Understanding Of Iron Gall Ink And Its Counterparts, Meredith Oliver

Honors Theses

This paper examines the physical and chemical composition of iron gall ink, how such composition has changed throughout its use in history, and the current chemical, digital, and multi-spectral methods by which the digital humanities use to preserve ancient texts inscribed with such ink. By using spectral technology, I hypothesized it possible to date and locate the geographic origin of ink based on its chemical composition. Uv-vis, fluorescence, and micro-XRF spectrometry were used to analyze elemental composition. Ink samples were made to simulate the ink on ancient manuscripts for UV-vis and fluorescence spectral analysis. Micro-XRF was performed on the Vercelli …

Breastfeeding: Physiological And Cultural Influences, Alison R. Cegielski

Honors Theses

Within a biological perspective, breasts are indisputably for the use of nourishment of the young. This can be seen by how mammary glands are used by every other species other than humans. Humans are the only species that also looks at breasts within a cultural perspective, and that perspective is where the debate of breastfeeding occurs. There is really no debate that if given the option to breastfeed, breastfeeding is the best choice for the development of infants due to the fact that breast milk has been adapted for the human physique. In spite of the health benefits associated with …

Curcumin: A Folklore Remedy From Kitchen On The Way To Clinic As Cancer Drug, Debasish Bandyopadhyay

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Numerous compounds are widely distributed in nature and many of these possess medicinal/biological/pharmacological activity. Curcumin, a polyphenol derived from the rhizomes (underground stems) of Curcuma longa Linn (a member of the ginger family, commonly known as turmeric) is a culinary spice and therapeutic used in India for thousands of years to induce color and flavor in food as well as to treat a wide array of diseases. The origin of turmeric as spice and folklore medicine is so old that it is lost in legend. Curcumin has many beneficial pharmacological effects which includes, but are not limited with, antimicrobial, anti-inflammatory, …

Does Low-Level Arsenic Exposure Predict Blood Pressure In Children?, Tania Angelica Mayorga

Open Access Theses & Dissertations

Background & Significance: Inorganic arsenic is a heavy metal naturally found in soil and human exposure to this heavy metal causes adverse effects. Exposure risks are particularly high in developing children. Arsenic is mainly found in bedrock. It is also a by-product of smelting, it is used in cement production, and historically is has been found in crop pesticides. Among other ill-effects, arsenic exposure in humans can cause respiratory diseases, peripheral neuropathy and liver fibrosis. In particular arsenic has been shown in many studies to be a contributing factor in the risk for hypertension in adults however no studies have …

The Impacts Of Health Status And Exposure To Environmental Toxins On Children's Grade Point Average In El Paso, Texas, Stephanie Elizabeth Clark

Open Access Theses & Dissertations

Studies in the US have found that both exposure to environmental toxins and children's general health status negatively impact children's academic achievement. This Thesis will be made of up two papers. The first examines the impact of exposure to residential air toxins from a variety of sources on student's academic achievement and the second paper incorporates a measure of children's general health status into the statistical model from the first paper. This Thesis employs National Air Toxics Assessment (NATA) risk estimates from a variety of sources and individual-level data collected through a mail survey of fourth and fifth grade school …

Exploratory Study Of Seasonal Indoor Bioaerosols And The Associated Health Outcomes In Low-Income Communities In El Paso, Texas, 2014, Eric Martinez

Open Access Theses & Dissertations

Introduction: Structural degradation, moisture levels, and building failures can influence poor indoor air quality and create a good environment for bioaerosols. People spend much of their time indoors and can potentially be exposed to these bioaerosols. Several studies have correlated exposures to high concentrations of bioaerosols to various health problems, severe allergies, asthma, or other respiratory illness. Objectives: The objectives of this study are to describe bioaerosol concentrations, meteorological factors, and health outcomes during the summer and fall seasons; characterize bioaerosols (bacteria and fungi) collected in low-income communities; compare bioaerosol concentrations by season; compare meteorological factors to bioaerosol concentrations by …

Pre-Tuned Ridge Regression And Its Extension To Generalized Linear Models, Yaa Tawiah Wonkye

Open Access Theses & Dissertations

Ridge regression is regularization or shrinkage method and a common approach in dealing with multicollinearity in conventional regression analysis. Ridge regression is widely used by statistical analyst since it is one of the best compared to other regularization methods. Also, the introduction of high dimension and ultra-high dimensional data has become an issue of concern and ridge regression is one way of dealing with such data. One of the key issues associated with ridge regression is the determination of the tuning or ridge parameter. The common practice is to fit ridge regression for a different number of values of tuning …

A Qualitative Analysis Of Migrant Women Farmworkers' A Qualitative Analysis Of Migrant Women Farmworkers’ Perceptions Of Maternal Care Management, Stacey A. Pilling

Walden Dissertations and Doctoral Studies

The purpose of this phenomenological study was to examine migrant women farmworkers' views of perinatal care management while working in the fields. Like men, women migrant farmworkers are exposed to many physical, chemical, and biological hazards that pose human health risks. However, women of childbearing age are at an increased risk of having reproductive health difficulties and adverse pregnancy outcomes, and the infant mortality rate among migrant farmworkers is estimated to be twice the national average. Perinatal care is a critical factor in reducing adverse outcomes for perinatal and newborn mortality. Face-to-face interviews were conducted with 15 migrant women farmworkers …

The Role Of Intermembrane Space Redox Factors In Glutathione Metabolism And Intracellular Redox Equilibrium, Hatice Kubra Ozer

Theses and Dissertations

The mitochondrial intermembrane space (IMS) is a unique subcellular compartment that houses key thiol-dependent redox pathways such as protein transport, mitochondrial respiration, and detoxification of ROS (reactive oxygen species). These pathways are all dependent on cysteine-rich proteins, thus maintaining thiol-disulfide balance in this organelle is crucial for cellular functions. An IMS protein import pathway called the Mia40-Erv1 disulfide relay system uses disulfide bond formation for the import and retention of substrate proteins in the IMS. Erv1 is also suggested to be involved in maturation of cytosolic Fe-S cluster proteins and regulation of iron homeostasis in S. cerevisiae. However, these studies …

The Scientist, 2015, San Jose State University, College Of Science

The Scientist (College of Science)

No abstract provided.

The Influence Of Eastern Oyster (Crassostrea Virginica) Reef Restoration On Nitrogen Cycling In A Eutrophic Estuary., Michael Hassett

Master's Theses

Oysters (Crassostrea virginica) are functionally extinct in the urbanized Hudson-Raritan estuary (HRE) in New York City, however, oyster restoration is promoted to mitigate nitrogen (N) pollution via oysters' filtration and excretion. Seasonally, I took 12 sediment cores (45 cm2) adjacent to and 10 m away from a recently constructed reef in the HRE. Cores were incubated in flow-through chambers with site water containing (1) no amendments, (2) 15N-ammonium, or (3) 15N-nitrate, from which I calculated coupled nitrification-denitrification and direct denitrification as isotope-enriched N2. Coupled denitrification was minimal at all sites while direct denitrification was elevated near the reef, suggesting organic …

Gmos, Nate Bohm-Levine

The Synapse: Intercollegiate science magazine

No abstract provided.

Against The Grain, Dayna Gallagher, Jenn Feigin

The Synapse: Intercollegiate science magazine

No abstract provided.

Unpacking Postharvest Losses In Sub-Saharan Africa: A Meta-Analysis, Hippolyte Affognon, Christopher Mutungi, Pascal Sanginga, Christian Borgemeister

All Peer-Reviewed Publications

Reducing postharvest losses (PHL) is a key pathway to food and nutrition security in sub-Saharan Africa. However, knowledge of PHL magnitudes is limited. A meta-analysis has been conducted to expose nature and magnitude of PHL, and the kinds of interventions that have been attempted to mitigate the losses. Findings reveal inadequacies of loss assessment methodologies that result in inaccurate PHL estimates. Moreover, losses are often economic rather than physical product losses. Overall, technologies for loss mitigation fail to address dynamics of supply chains. Consequently, rigorous PHL assessment using systematic methodologies, as well as holistic approaches for losses mitigation are in …

A Comparison Of Obesity Interventions Using Energy Balance Models, Marcella Torres

Theses and Dissertations

An energy balance model of human metabolism developed by Hall et al. is extended to compare body composition outcomes among standard and proposed obesity interventions. Standard interventions include a drastic diet or a drastic diet with endurance training. Outcomes for these interventions are typically poor in clinical studies. Proposed interventions include a gradual diet and the addition of resistance training to preserve lean mass and metabolic rate. We see that resistance training, regardless of dietary strategy, achieves these goals. Finally, we observe that the optimal obesity intervention for continued maintenance of a healthy body composition following a diet includes a …

Refraction In Mozambique: Evaluations Of Practice And Development Of Competency Frameworks For Eye Care Personnel, Kajal Shah

Doctoral

Purpose The development of competency- based education for optometrists and mid-level eye-care personnel has been identified as an important component in the elimination of avoidable blindness and vision impairment. The Mozambique Eye care Project (MEP) is a multi-institutional collaboration, which seeks to facilitate greater access to training in eye health professions, which will ultimately contribute to providing affordable and accessible eye care within the public health system in Mozambique. An important tenet of the MEP is to develop and enhance the refraction training of all existing (ophthalmic technicians) and new eye care personnel (four-year training of optometrists and eighteen-month training …

Negative Feedbacks On Bark Beetle Outbreaks: Widespread And Severe Spruce Beetle Infestation Restricts Subsequent Infestation, Sarah J. Hart, Thomas T. Veblen, Nathan Mietkiewicz, Dominik Kulakowski

Geography

Understanding disturbance interactions and their ecological consequences remains a major challenge for research on the response of forests to a changing climate. When, where, and how one disturbance may alter the severity, extent, or occurrence probability of a subsequent disturbance is encapsulated by the concept of linked disturbances. Here, we evaluated 1) how climate and forest habitat variables, including disturbance history, interact to drive 2000s spruce beetle (Dendroctonus rufipennis) infestation of Engelmann spruce (Picea engelmannii) across the Southern Rocky Mountains; and 2) how previous spruce beetle infestation affects subsequent infestation across the Flat Tops Wilderness in northwestern Colorado, which experienced …

A Case Study On In Vitro Investigations Of The Potent Biological Activities Of Wheat Germ And Black Cumin Seed Oil, Di̇dem Ağ Şeleci̇, Zi̇nar Pinar Gümüş, Murat Yavuz, Muharrem Şeleci̇, Rebecca Bongartz, Frank Stahl, Hakan Coşkunol, Suna Ti̇mur, Thomas Scheper

Turkish Journal of Chemistry

The objectives of this study were to investigate the potential biological activities of black cumin seed oil (BCSO) and wheat germ oil (WGO) on different cell lines. Initially, commercially available BCSO and WGO obtained by supercritical carbon dioxide extraction were analyzed in terms of tocopherol, aliphatic alcohols, and thymoquinone content via HPLC and GC analysis. Cell free antioxidant activities and total phenolic content of both oils were detected by DPPH assay and Folin-Ciocalteu method, respectively. As well as the DPPH assay, the protective effect against reactive oxygen species (ROS) was determined by microscopic observation of ROS generation in NIH-3T3 cells …

The Distribution Of Type 1 Diabetes Onset In The United States By Demographic Factors, Margaret Beckstrand

Walden Dissertations and Doctoral Studies

Type 1 diabetes (T1D) is a chronic and lifelong condition, often diagnosed in childhood. Patients with T1D are at elevated risks of associated health complications, comorbidities, and mortality. Occurrence, clinical presentation, and complications related to T1D differ by age of onset, ethnicity, and gender. The last reported population-based estimates regarding the burden of T1D in children using the National Health and Nutrition Examination Survey (NHANES) were published in 2008, and these estimates were not well stratified by age of onset, ethnicity, and gender. The purpose of this study was to examine these demographics within the conceptual framework of the hygiene …

Synthesis And Biological Evaluation Of Novel Fused Triazolo[4,3-$A$] Pyrimidinones, Ikhlass Abbas, Sobhi Gomha, Mohamed Elneairy, Mahmoud Elaasser, Bazada Mabrouk

Turkish Journal of Chemistry

The reaction of thione 3 or its 2-methylthio derivative 4 with hydrazonoyl halides 5a-l, in the presence of triethylamine, yielded the corresponding triazolo[4,3-$a$]pyrimidin-5(1$H)$-ones 8a-l. The structure of compounds 8a-l was further confirmed by the reaction of 3 with the appropriate active chloromethylenes 11a-c followed by coupling of the products with benzenediazonium chloride to afford the azo-coupling products 6b, f, and j, which were converted in situ to 8b, f, and j. 2-Hydrazinyl-pyrido[3',2':4,5]thieno[3,2-$d$]pyrimidin-4(3$H)$-one (13) was prepared and condensed with different aldehydes 14a-f to give the corresponding hydrazone derivatives 15a-f. Oxidative cyclization of the hydrazones 15a-f give the corresponding triazolo[4,3-$a$] pyrimidin-5(1$H)$-one derivatives …

Understanding Ocean Acidification Impacts On Organismal To Ecological Scales, Andreas J. Andersson, David I. Kline, Peter J. Edmunds, Stephen D. Archer, Nina Bednarsek, Robert C. Carpenter, Meg Chadsey, Philip Goldstein, Andrea G. Grottoli, Thomas P. Hurst, Andrew L. King, Janet E. Kübler, Ilsa B. Kuffner, Katherine R.M. Mackey, Bruce A. Menge, Adina Paytan, Ulf Riebesell, Astrid Schnetzer, Mark E. Warner, Richard C. Zimmerman

OES Faculty Publications

Ocean acidification (OA) research seeks to understand how marine ecosystems and global elemental cycles will respond to changes in seawater carbonate chemistry in combination with other environmental perturbations such as warming, eutrophication, and deoxygenation. Here, we discuss the effectiveness and limitations of current research approaches used to address this goal. A diverse combination of approaches is essential to decipher the consequences of OA to marine organisms, communities, and ecosystems. Consequently, the benefits and limitations of each approach must be considered carefully. Major research challenges involve experimentally addressing the effects of OA in the context of large natural variability in seawater …

Interpretation Of Complexometric Titration Data: An Intercomparison Of Methods For Estimating Models Of Trace Metal Complexation By Natural Organic Ligands, I. Pižeta, S. G. Sander, R. J. M. Hudson, D. Omanović, O. Baars, K. A. Barbeau, K. N. Buck, R. M. Bundy, G. Carrasco, P. L. Croot

OES Faculty Publications

With the common goal of more accurately and consistently quantifying ambient concentrations of free metal ions and natural organic ligands in aquatic ecosystems, researchers from 15 laboratories that routinely analyze trace metal speciation participated in an intercomparison of statistical methods used to model their most common type of experimental dataset, the complexometric titration. All were asked to apply statistical techniques that they were familiar with to model synthetic titration data that are typical of those obtained by applying state-of-the-art electrochemical methods – anodic stripping voltammetry (ASV) and competitive ligand equilibration-adsorptive cathodic stripping voltammetry (CLE-ACSV) – to the analysis of natural …

Heterotrophic And Autotrophic Contribution To Dinitrogen Fixation In The Gulf Of Aqaba, Eyal Rahav, Barak Herut, Margaret R. Mulholland, Natalia Belkin, Hila Elifantz, Ilana Berman-Frank

OES Faculty Publications

We evaluated the seasonal contribution of heterotrophic and autotrophic diazotrophy to the total dinitrogen (N₂) fixation in the photic zone of a pelagic station in the northern Gulf of Aqaba, Red Sea. N₂ fixation rates were highest during a Trichodesmium bloom in winter (0.7 nmol N l^-1 d^-1), decreased 7-fold 1 wk later throughout the upper 200 m (~0.1 nmol N l^-1) d^-1), and were significantly coupled with both primary and bacterial productivity. N₂ fixation rates were generally higher in the upper 200 m (~0.4 nmol N l^{-1 …}

New Tracer To Estimate Community Predation Rates Of Phagotrophic Protists, Alexander B. Bochdansky, Melissa A. Clouse

OES Faculty Publications

Predation of eukaryotic microbes on prokaryotes is one of the most important trophic interactions on Earth, representing a major mortality term and shaping morphology and composition of prokaryotic communities. Here we introduce and validate a new tracer to determine predation rates on prokaryotes. Minicells of Escherichia coli marked with a bright green fluorescent protein (GFP) vector have many operational advantages over previously used prey analogs such as fluorescently labeled bacteria. GFP-minicells are similar in size to naturally occurring bacteria from a variety of environments including the oligotrophic open ocean and the deep sea. They are relatively stable against microbial and …

Genetic Indicators Of Iron Limitation In Wild Populations Of Thalassiosira Oceanica From The Northeast Pacific Ocean, P. Dreux Chappell, Leann P. Whitney, Joselynn R. Wallace, Adam I. Darer, Samua Jean-Charles, Bethany D. Jenkins

OES Faculty Publications

Assessing the iron (Fe) nutritional status of natural diatom populations has proven challenging as physiological and molecular responses can differ in diatoms of the same genus. We evaluated expression of genes encoding flavodoxin (FLDA1) and an Fe-starvation induced protein (ISIP3) as indicators of Fe limitation in the marine diatom Thalassiosira oceanica. The specificity of the response to Fe limitation was tested in cultures grown under Fe-and macronutrient-deficient conditions, as well as throughout the diurnal light cycle. Both genes showed a robust and specific response to Fe limitation in laboratory cultures and were detected in small volume samples collected from …

Ph Dependent Antibiotic Resistance Of An Alkaliphilic, Halotolerant Bacterium Isolated From Soap Lake, Washington, Tiffany Charlynn Edwards

Masters Theses

"Soap Lake, located in Washington State, is a meromictic, soda lake. Many bacterial isolates retrieved from Soap Lake have been noted to possess resistance to multiple antibiotics. A likely explanation for the wide range of antibacterial resistance exhibited by these strains is due to the impact of high alkalinity on the antibiotics themselves and not due to the presence of antibiotic resistance genes. The aim of our study was to determine if select antibiotics are effective against Halomonas eurialkalitoleranis, a bacterium capable of growth over a wide range of neutral to alkaline pH values, to investigate the influence of alkalinity …

The Contribution Of Non-Thermal And Advanced Oxidation Technologies Towards Dissipation Of Pesticide Residues, N. Misra

Articles

Background

The use of pesticides has stabilised the food production to a great extent and their usage cannot be avoided anymore. Nevertheless, common food processing operations always allowed dissipating pesticide residues in foods to some extent. Within the food science community and the food processing sector, non-thermal food technologies are being researched and commercialised at a great pace over the past three decades.

Scope and Approach

In this review we provide a critical analysis of the literature pertinent to the fate of pesticide residues during non-thermal processing of solid and liquid foods. We also identify the opportunities for further development …

A Rapid And High Content Assay That Measures Cyto-Id-Stained Autophagic Compartments And Estimates Autophagy Flux With Potential Clinical Applications, Sujuan Guo, Yanping Liang, Susan F. Murphy, Angela Huang, Haihong Shen, Deborah F. Kelly, Pablo Sobrado, Zhi Sheng

Chemistry Faculty Research & Creative Works

The lack of a rapid and quantitative autophagy assay has substantially hindered the development and implementation of autophagy-targeting therapies for a variety of human diseases. To address this critical issue, we developed a novel autophagy assay using the newly developed Cyto-ID fluorescence dye. We first verified that the Cyto-ID dye specifically labels autophagic compartments with minimal staining of lysosomes and endosomes. We then developed a new Cyto-ID fluorescence spectrophotometric assay that makes it possible to estimate autophagy flux based on measurements of the Cyto-ID-stained autophagic compartments. By comparing to traditional autophagy approaches, we found that this assay yielded a more …