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Reproductive Characteristics Of Landlocked Fall Chinook Salmon From Lake Oahe, South Dakota, Kelsen L. Young, Michael E. Barnes, Jeremy L. Kientz Dec 2016

Reproductive Characteristics Of Landlocked Fall Chinook Salmon From Lake Oahe, South Dakota, Kelsen L. Young, Michael E. Barnes, Jeremy L. Kientz

The Prairie Naturalist

Lake Oahe, South Dakota, USA, landlocked fall Chinook salmon (Oncorhynchus tshawytscha) reproductive characteristics were examined over a 27 year period, from 1988 to 2015. Mean total lengths of spawning females ranged from 665 mm (1995) to 812 mm (2015) with considerable year-to-year variation. Post-spawn female weights varied, ranging from 2.02 kg (2000) to 5.55 kg (2015), with an overall mean of 3.04 kg. Fecundity peaked at 4,555 eggs per female in 2003, which was just 3 years after a low of 2,011 eggs per female in 2000. Relative fecundity based on female weight was greatest at 1,211 eggs/kg …


Multiplencc: Inverse Probability Weighting Of Nested Case-Control Data, Nathalie C. Støer, Sven Ove Samuelsen Dec 2016

Multiplencc: Inverse Probability Weighting Of Nested Case-Control Data, Nathalie C. Støer, Sven Ove Samuelsen

The R Journal

Reuse of controls from nested case-control designs can increase efficiency in many situations, for instance with competing risks or in other multiple endpoints situations. The matching between cases and controls must be broken when controls are to be used for other endpoints. A weighted analysis can then be performed to take care of the biased sampling from the cohort. We present the R package multipleNCC for reuse of controls in nested case-control studies by inverse probability weighting of the partial likelihood. The package handles right-censored, left-truncated and additionally matched data, and varying numbers of sampled controls and the whole analysis …


Reduced Snow Cover Alters Root-Microbe Interactions And Decreases Nitrification Rates In A Northern Hardwood Forest, Patrick O. Sorensen, Pamela H. Templer, Lynn M. Christenson, Jorge Durán, Timothy J. Fahey, Melany C. Fisk, Peter M. Groffman, Jennifer L. Morse, Adrien C. Finzi Dec 2016

Reduced Snow Cover Alters Root-Microbe Interactions And Decreases Nitrification Rates In A Northern Hardwood Forest, Patrick O. Sorensen, Pamela H. Templer, Lynn M. Christenson, Jorge Durán, Timothy J. Fahey, Melany C. Fisk, Peter M. Groffman, Jennifer L. Morse, Adrien C. Finzi

Environmental Science and Management Faculty Publications and Presentations

Snow cover is projected to decline during the next century in many ecosystems that currently experience a seasonal snowpack. Because snow insulates soils from frigid winter air temperatures, soils are expected to become colder and experience more winter soil freeze-thaw cycles as snow cover continues to decline. Tree roots are adversely affected by snowpack reduction, but whether loss of snow will affect root-microbe interactions remains largely unknown. The objective of this study was to distinguish and attribute direct (e.g., winter snow-and/ or soil frost-mediated) vs. indirect (e.g., root-mediated) effects of winter climate change on microbial biomass, the potential activity of …


Liming Characteristics Of A High-Calcium, Dry Flue Gas Desulfurization By-Product And Its Effects On Runoff Water Quality, Jason Richard Burgess-Conforti Dec 2016

Liming Characteristics Of A High-Calcium, Dry Flue Gas Desulfurization By-Product And Its Effects On Runoff Water Quality, Jason Richard Burgess-Conforti

Graduate Theses and Dissertations

In 2013, only 37% of the 32 million Mg of flue gas desulfurization (FGD) by-products generated in the United States were reused beneficially. If FGD by-products could be used as a beneficial soil amendment, millions of megagrams may be diverted away from surface impoundments and landfills. The purpose of this research was to identify the liming characteristics of a high-Ca dry FGD (DFGD) by-product in comparison to a Class-C fly ash (FA) and reagent-grade CaCO3, and to evaluate the effects of land application to a managed grassland on runoff, plant, and soil quality. Liming characteristics were determined by measuring the …


Cover Crop Establishment And Potential Benefits To Arkansas Farmers, Ashley Elizabeth Humphreys Dec 2016

Cover Crop Establishment And Potential Benefits To Arkansas Farmers, Ashley Elizabeth Humphreys

Graduate Theses and Dissertations

Soybean farmers in Arkansas need best management practices (BMPs) that maximize the benefits of using cover crops including planting date and fertilization recommendations. An evaluation of cover crop species, planting dates, seeding rates, fertilizer rates, and N accumulation aids in providing these BMPs. The first objective of this research is to assess the effect of planting date on biomass production, as well as looking at the interaction of seeding rate or fertilizer rate for legumes or non-legumes, respectively, using Austrian winter pea (Pisum sativum), cereal rye (Secale cereale), black oats (Avena strigosa), wheat (Triticum aestivum), and tillage radish (Raphanus sativus). …


Complex Vegetation Dynamics At The Fire–Grazing–Drought Nexus, Christine H. Bielski Dec 2016

Complex Vegetation Dynamics At The Fire–Grazing–Drought Nexus, Christine H. Bielski

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

The discipline of ecology long ago moved away from viewing systems as static entities where disturbance processes, environmental stochasticity, and spatiotemporal variability play minor roles in determining ecosystem structure and function. Ecological theory continue to develop frameworks and statistical techniques capable of describing the inherent complexity in natural systems. However, in dealing with the complexity in nature, many applied disciplines have yet to adopt such frameworks or statistical techniques. The objective of this study was bridge the gap between ecological theory and application by using complex systems theory to describe grassland vegetation dynamics at the fire-grazing-drought nexus. Chapters 2 and …


Exendin 4 Conjugation And Sequence Modification To Treat Type 2 Diabetes And Obesity, Ronald Bonaccorso Bonaccorso Dec 2016

Exendin 4 Conjugation And Sequence Modification To Treat Type 2 Diabetes And Obesity, Ronald Bonaccorso Bonaccorso

Dissertations - ALL

This thesis addresses three primary questions based on the pharmacodynamics (PD) or pharmacokinetics

(PK) of the diabetes drug exendin 4 (Ex-4), and vitamin B12 (B12) bioconjugates, thereof.

Q1. (Chapter 2) What effect does B12 conjugation to Ex-4 have on agonism of the glucagon-like peptide-1

receptor (GLP-1R) in vitro and on PD/PK (including brain uptake and function) in vivo?

Goal: To remove side-effects (nausea, weight loss) of Ex-4 without loss of glucoregulation.

Q2. (Chapter 3) Can B12 dietary uptake proteins such as gastric intrinsic factor offer protection to B12

conjugated peptides or proteins (focusing on Ex-4), with a view to improving …


Marine Microalgae: Climate, Energy, And Food Security From The Sea, Charles H. Greene, Mark E. Huntley, Ian Archibald, Léda N. Gerber, Deborah L. Sills, Joe Granados, Jefferson W. Tester, Colin M. Beal, Michael J. Walsh, Robert R. Bidigare, Susan L. Brown, William P. Cochlan, Zackary I. Johnson, Xin Gen Lei, Stephen C. Machesky, Donald Redalje, Ruth E. Richardson, Viswanath Kiron, Virginia Corless Dec 2016

Marine Microalgae: Climate, Energy, And Food Security From The Sea, Charles H. Greene, Mark E. Huntley, Ian Archibald, Léda N. Gerber, Deborah L. Sills, Joe Granados, Jefferson W. Tester, Colin M. Beal, Michael J. Walsh, Robert R. Bidigare, Susan L. Brown, William P. Cochlan, Zackary I. Johnson, Xin Gen Lei, Stephen C. Machesky, Donald Redalje, Ruth E. Richardson, Viswanath Kiron, Virginia Corless

Faculty Publications

Climate, energy, and food security are three of the greatest challenges society faces this century. Solutions for mitigating the effects of climate change often conflict with solutions for ensuring society’s future energy and food requirements. For example, BioEnergy with Carbon Capture and Storage (BECCS) has been proposed as an important method for achieving negative CO2 emissions later this century while simultaneously producing renewable energy on a global scale. However, BECCS has many negative environmental consequences for land, nutrient, and water use as well as biodiversity and food production. In contrast, large-scale industrial cultivation of marine microalgae can provide society with …


Determining The Effects Of The Think Risk Initiative As Implemented By The Southern Nevada Health District, Karalin Nichole Cronkhite Dec 2016

Determining The Effects Of The Think Risk Initiative As Implemented By The Southern Nevada Health District, Karalin Nichole Cronkhite

UNLV Theses, Dissertations, Professional Papers, and Capstones

In the United States, someone becomes infected with a foodborne illness every 2 seconds, is hospitalized by a foodborne illness every 4 minutes and dies due to a foodborne illness every 3 hours. Foodborne illness is preventable, yet each year, 1 in 6 Americans is affected by it from contaminated foods or beverages. There are over 250 different foodborne diseases, and in 2015, there were 73 confirmed cases of Salmonella infection in Southern Nevada alone. Since the emergence of public health, food establishment inspections have been an important part of the regulation of food safety. Risk-based inspections were developed by …


Bloom Or Bust: Retrospective Analysis Of The Giant Jellyfish, Nemopilema Nomurai (Scyphozoa: Rhizostomeae), Ecology In The East Asian Marginal Seas, Naomi Yoder Dec 2016

Bloom Or Bust: Retrospective Analysis Of The Giant Jellyfish, Nemopilema Nomurai (Scyphozoa: Rhizostomeae), Ecology In The East Asian Marginal Seas, Naomi Yoder

Master's Theses

The Giant Jellyfish, Nemopilema nomurai, is a large-bodied bloom-forming jellyfish that occurs in the semi-enclosed basins of the East Asian Marginal Seas. N. nomurai has bloomed more frequently in the past 20 years than in any period previously recorded. In Japan, recent N. nomurai blooms were responsible for millions of dollars in lost revenue and equipment damage to commercial fisheries alone. This study statistically analyzed 21 environmental factors in connection with N. nomurai occurrence (using occurrence as a proxy for blooms). Eight factors resulted in a statistically significant or marginally significant (p ≤ 0.10), linear or non-linear relationship with …


The Risk Of Pneumonia Among Toddlers In Lambatee, Aceh, Rapitos Sidiq, Ritawati Ritawati, Roma Sitio, Siti Hajar Nov 2016

The Risk Of Pneumonia Among Toddlers In Lambatee, Aceh, Rapitos Sidiq, Ritawati Ritawati, Roma Sitio, Siti Hajar

Kesmas

Pneumonia merupakan salah satu masalah kesehatan global yang sangat penting pada anak bawah lima tahun (balita), khususnya pada negara-negara berkembang. Saat ini, pneumonia merupakan salah satu kasus penyebab kematian pada anak terbesar, terutama pada periode baru lahir. Di Provinsi Aceh, penyakit pneumonia merupakan penyakit urutan ke-8 dari 25 penyakit terbesar yang ditemukan di puskesmas dengan jumlah 1.112 kasus. Sedangkan besarnya kasus pneumonia pada penderita rawat jalan di Aceh mencapai 434 kasus (29,03%). Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan kejadian pneumonia pada balita. Penelitian bersifat analitik dengan desain potong lintang. Sampel penelitian adalah ibu dan balita yang berjumlah …


Motivation Variables To Use Contraceptive Among Male In Yogyakarta, Susiana Sariyati, Febrina Suci Hati, Fatimah Fatimah Nov 2016

Motivation Variables To Use Contraceptive Among Male In Yogyakarta, Susiana Sariyati, Febrina Suci Hati, Fatimah Fatimah

Kesmas

Program Keluarga Berencana (KB) merupakan salah satu program pembangunan nasional yang sangat penting dalam rangka mewujudkan keluarga Indonesia yang sejahtera. Peran program KB sangat besar pengaruhnya terhadap kesehatan reproduksi seseorang, baik untuk kesehatan reproduksi perempuan maupun kesehatan reproduksi laki-laki. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan motivasi laki-laki pasangan usia subur dalam menggunakan kontrasepsi di Desa Bumijo, Kecamatan Jetis, Kota Yogyakarta. Jenis penelitian ini bersifat kuantitatif dengan analisis regresi logistik. Hasil penelitian menunjukkan hubungan pengetahuan dengan motivasi yaitu nilai p = 0,368. Hubungan sosial budaya dengan motivasi yaitu nilai p = 0,147. Hubungan pendidikan dengan motivasi yaitu nilai …


Family Planning Information, Education And Communication With Contaceptive Use, Endah Winarni, Muhammad Dawam Nov 2016

Family Planning Information, Education And Communication With Contaceptive Use, Endah Winarni, Muhammad Dawam

Kesmas

Komunikasi Informasi dan Edukasi (KIE) berperan penting dalam meningkatkan pencapaian prevalensi kesertaan Keluarga Berencana (KB). Namun, prevalensi KB di Indonesia selama satu dekade terakhir (2002-2012) tidak meningkat secara signifikan, walaupun pelbagai kegiatan KIE KB telah dilaksanakan. Penelitian ini bertujuan untuk mengetahui faktor sosio ekonomi demografi yang berkaitan dengan KIE KB, pelbagai unsur KIE yang berkaitan dengan pemakaian KB, dan unsur KIE yang berpengaruh terhadap pemakaian KB. Analisis menggunakan sumber data Survei Demografi dan Kesehatan Indonesia 2012 dengan unit analisis perempuan berstatus kawin usia 15-49 tahun. Jumlah sampel yang dianalisis 33.465 perempuan berstatus kawin. Analisis menggunakan odds ratio atau rasio kecenderungan …


Social Determinant Of Health Of Adults Smoking Behavior: Differences Between Urban And Rural Areas In Indonesia, Fitri Kurnia Rahim, Thunwadee Suksaroj, Isareethika Jayasvasti Nov 2016

Social Determinant Of Health Of Adults Smoking Behavior: Differences Between Urban And Rural Areas In Indonesia, Fitri Kurnia Rahim, Thunwadee Suksaroj, Isareethika Jayasvasti

Kesmas

Indonesia memiliki prevalensi perilaku merokok tertinggi di antara negara-negara di Asia Tenggara. Penelitian ini bertujuan untuk mengetahui prediktor terhadap perilaku merokok antara wilayah pedesaan dan perkotaan. Data diambil dari Global Adult Tobacco Survey. Penelitian menggunakan studi analitik potong lintang dan analisis regresi logistik ganda. Sampel berjumlah 8.305 orang dewasa Indonesia berusia ≥ 15 tahun. Penelitian menunjukkan bahwa perokok di wilayah pedesaan lebih tinggi dibandingkan di wilayah perkotaan, masing-masing 36,8% dan 31,9%. Prediktor signifikan terhadap perilaku merokok di wilayah pedesaan dan perkotaan adalah usia, pekerjaan, jenis kelamin, tingkat pendidikan, status ekonomi serta aturan merokok di dalam rumah. Di wilayah perkotaan, usia …


Effectivity Of Foot Care Education Program In Improving Knowledge, Self-Efficacy And Foot Care Behavior Among Diabetes Mellitus Patients In Banjarbaru, Indonesia, Mahdalena Mahdalena, Endang Sri Purwanti Ningsih Nov 2016

Effectivity Of Foot Care Education Program In Improving Knowledge, Self-Efficacy And Foot Care Behavior Among Diabetes Mellitus Patients In Banjarbaru, Indonesia, Mahdalena Mahdalena, Endang Sri Purwanti Ningsih

Kesmas

Masalah kaki diabetik di Indonesia masih merupakan masalah besar dan masih memerlukan perhatian yang optimal. Edukasi perawatan kaki adalah salah satu upaya yang harus dilakukan dalam mencegah masalah kaki untuk pasien diabetes melitus. Penelitian ini bertujuan untuk menganalisis efektivitas program pendidikan perawatan kaki dalam meningkatkan pengetahuan, efikasi diri, dan perilaku perawatan kaki pasien diabetes di wilayah Banjarbaru. Jenis penelitian yang digunakan adalah quasi experimental dengan prepost test, dilakukan di puskesmas wilayah Banjarbaru tahun 2013. Kelompok intervensi diberikan program pendidikan perawatan kaki. Sampel berjumlah 48 pasien (32 orang kelompok intervensi dan 16 orang kelompok kontrol) menggunakan teknik purposive sampling. Variabel yang …


Lack Of Exclusive Breastfeeding Among Working Mothers In Indonesia, Yulia Sari Nov 2016

Lack Of Exclusive Breastfeeding Among Working Mothers In Indonesia, Yulia Sari

Kesmas

Keberlangsungan proses menyusui pada saat ibu kembali bekerja merupakan isu serius yang harus segera ditindaklanjuti agar program pemberian Air Susu Ibu (ASI) eksklusif selama enam bulan pertama kehidupan dapat tercapai. Selain memberikan banyak manfaat bagi bayi, ASI juga bermanfaat bagi ibu dan pengusaha. Penelitian ini bertujuan untuk mengetahui hubungan ibu bekerja terhadap pemberian ASI eksklusif. Desain penelitian yang digunakan adalah potong lintang dengan data sekunder Survei Demografi dan Kesehatan Indonesia (SDKI) tahun 2012 dengan sampel berjumlah 1.193 ibu berusia 15 – 49 tahun yang memiliki bayi berusia 0-5 bulan. Berdasarkan analisis multivariat, ibu bekerja dapat menurunkan peluang pemberian ASI eksklusif …


Coronary Heart Disease Risk Factors Among Women Aged Older Than 45 Years Old In Makassar, Masriadi Masriadi, Hasta Handayani Idrus, Arman Arman Nov 2016

Coronary Heart Disease Risk Factors Among Women Aged Older Than 45 Years Old In Makassar, Masriadi Masriadi, Hasta Handayani Idrus, Arman Arman

Kesmas

Penyakit kardiovaskuler menyebabkan 8.6 juta kematian pada perempuan setiap tahun, yang merupakan penyebab kematian terbanyak, yaitu sepertiga dari seluruh kematian perempuan di seluruh dunia. Setengah dari seluruh kematian perempuan berusia di atas 50 tahun disebabkan oleh penyakit jantung dan stroke. Penelitian ini bertujuan untuk menganalisis faktor yang berhubungan dengan penyakit jantung koroner pada perempuan usia > 45 tahun di Rumah Sakit TNI AU Dody Sarjoto Makassar. Besar sampel sebanyak 76 sampel yang terdiri dari 64 kasus penyakit jantung koroner dan 12 kasus non penyakit jantung koroner. Penentuan sampel menggunakan metode purposive sampling. Data primer diperoleh melalui wawancara terhadap responden dengan menggunakan …


Basis For Development Of Business Strategic Plan Primary Health Care With Local Public Service Entity Status In Gianyar District, Putu Ayu Indrayathi, Luh Putu Sinthya Ulandari Nov 2016

Basis For Development Of Business Strategic Plan Primary Health Care With Local Public Service Entity Status In Gianyar District, Putu Ayu Indrayathi, Luh Putu Sinthya Ulandari

Kesmas

Puskesmas yang berbentuk Badan Layanan Umum Daerah (BLUD) perlu membuat rencana strategi bisnis yang tepat. Penyusunan rencana strategi bisnis perlu memerhatikan pesaing yang beroperasi di sekitar wilayah kerja. Penelitian ini bertujuan untuk mempelajari aspek lingkungan internal dan eksternal di Puskesmas Ubud 1 dan Tegallalang 1 serta mengembangkan model pengembangan rencana strategi bisnis di kedua puskesmas yang berstatus BLUD tersebut. Penelitian ini merupakan penelitian deskriptif eksploratif yang dilakukan pada tahun 2014. Data dikumpulkan melalui penyebaran kuesioner dan studi dokumentasi. Sampel penelitian ditentukan secara purposif dan diambil secara non proporsional, terdiri dari kepala dan staf Puskesmas Ubud 1 dan Tegallalalng 1. Data …


Robustness Of The Potential And Flux Landscapes In Fission Yeast Cell Cycle Networks, Xiaosheng Luo Nov 2016

Robustness Of The Potential And Flux Landscapes In Fission Yeast Cell Cycle Networks, Xiaosheng Luo

Theses and Dissertations

Using fission yeast cell cycle as an example, we uncovered that the non-equilibrium network dynamics and global properties are determined by two essential features: the potential landscape and the flux landscape. While potential landscape quantifies the probabilities of different states forming hills and valleys, the flux landscape quantifies the probability fluxes of different loops flowing through states. These two landscapes can be quantified through the decomposition of the dynamics into the detailed balance preserving part and detailed balance breaking non-equilibrium part. While the funneled potential landscape is often crucial for the stability of the single attractor networks, we have uncovered …


Using Sensitivity Analyses For Unobserved Confounding To Address Covariate Measurement Error In Propensity Score Methods, Kara E. Rudolph, Elizabeth A. Stuart Nov 2016

Using Sensitivity Analyses For Unobserved Confounding To Address Covariate Measurement Error In Propensity Score Methods, Kara E. Rudolph, Elizabeth A. Stuart

Johns Hopkins University, Dept. of Biostatistics Working Papers

Propensity score methods are a popular tool to control for confounding in observational data, but their bias-reduction properties are threatened by covariate measurement error. There are few easy-to-implement methods to correct for such bias. We describe and demonstrate how existing sensitivity analyses for unobserved confounding---propensity score calibration, Vanderweele and Arah's bias formulas, and Rosenbaum's sensitivity analysis---can be adapted to address this problem. In a simulation study, we examined the extent to which these sensitivity analyses can correct for several measurement error structures: classical, systematic differential, and heteroscedastic covariate measurement error. We then apply these approaches to address covariate measurement error …


Inflammatory Properties Of Diet And Glucose-Insulin Homeostasis In A Cohort Of Iranian Adults, Nazanin Moslehi, Behnaz Ehsani, Parvin Mirmiran, Nitin Shivappa, Maryam Tohidi, James R. Hébert, Fereidoun Azizi Nov 2016

Inflammatory Properties Of Diet And Glucose-Insulin Homeostasis In A Cohort Of Iranian Adults, Nazanin Moslehi, Behnaz Ehsani, Parvin Mirmiran, Nitin Shivappa, Maryam Tohidi, James R. Hébert, Fereidoun Azizi

Faculty Publications

We aimed to investigate associations of the dietary inflammatory index (DII) with glucose-insulin homeostasis markers, and the risk of glucose intolerance. This cross-sectional study included 2975 adults from the Tehran Lipid and Glucose Study. Fasting plasma glucose (FPG), 2-h post-load glucose (2h-PG), and fasting serum insulin were measured. Homeostatic model assessment of insulin resistance index (HOMA-IR) and β-cell function (HOMA-B), and the quantitative insulin sensitivity check index (QUICKI) were calculated. Glucose tolerance abnormalities included impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and type 2 diabetes (T2DM). DII scores were positively associated with 2h-PG (β = 0.04; p = 0.05). …


Inhibition Of The Flavin-Dependent Monooxygenase Siderophore A (Sida) Blocks Siderophore Biosynthesis And Aspergillus Fumigatus Growth, Julia S. Martín Del Campo, Nancy Vogelaar, Karishma Tolani, Karina Kizjakina, Kim Harich, Pablo Sobrado Nov 2016

Inhibition Of The Flavin-Dependent Monooxygenase Siderophore A (Sida) Blocks Siderophore Biosynthesis And Aspergillus Fumigatus Growth, Julia S. Martín Del Campo, Nancy Vogelaar, Karishma Tolani, Karina Kizjakina, Kim Harich, Pablo Sobrado

Chemistry Faculty Research & Creative Works

Aspergillus fumigatus is an opportunistic fungal pathogen and the most common causative agent of fatal invasive mycoses. The flavin-dependent monooxygenase siderophore A (SidA) catalyzes the oxygen and NADPH dependent hydroxylation of l-ornithine (l-Orn) to N5-l-hydroxyornithine in the biosynthetic pathway of hydroxamate-containing siderophores in A. fumigatus. Deletion of the gene that codes for SidA has shown that it is essential in establishing infection in mice models. Here, a fluorescence polarization high-throughput assay was used to screen a 2320 compound library for inhibitors of SidA. Celastrol, a natural quinone methide, was identified as a noncompetitive inhibitor of SidA with a MIC value …


Efficiency Of An Unbalanced Design In Collecting Time To Event Data With Interval Censoring, Peiyao Cheng Nov 2016

Efficiency Of An Unbalanced Design In Collecting Time To Event Data With Interval Censoring, Peiyao Cheng

USF Tampa Graduate Theses and Dissertations

In longitudinal studies, the exact timing of an event often cannot be observed, and is usually detected at a subsequent visit, which is called interval censoring. Spacing of the visits is important when designing study with interval censored data. In a typical longitudinal study, the spacing of visits is usually the same across all subjects (balanced design). In this dissertation, I propose an unbalanced design: subjects at baseline are divided into a high risk group and a low risk group based on a risk factor, and the subjects in the high risk group are followed more frequently than those in …


Effects Of Antibiotic Mixtures Across Marine Intertidal Trophic Levels: Examining Environmentally-Relevant Contaminant Concentrations, Jaclyn Rebecca Teixeira Nov 2016

Effects Of Antibiotic Mixtures Across Marine Intertidal Trophic Levels: Examining Environmentally-Relevant Contaminant Concentrations, Jaclyn Rebecca Teixeira

Dissertations and Theses

Approximately 48% of Americans use prescription drugs within each 30-day period, and there are signs this trend is increasing. Although many studies track pharmaceuticals’ fates in contaminating waterways, only fairly recent efforts have examined the potential impacts of these drugs on non-target organisms. The antibiotics sulfamethoxazole and trimethoprim, often prescribed together to treat bacterial infections, have been detected worldwide in marine and estuarine environments at concentrations up to 700-800 ng/L each. Toxic effects of these drugs have been identified in freshwater organisms, with synergistic effects observed in short-term studies of mixtures of the two; however, little research has examined possible …


Automated Calibration Of Atmospheric Oxidized Mercury Measurements, Seth Lyman, Colleen Jones, Trevor O'Neil, Tanner Allen, Matthieu Miller, Mae Sexauer Gustin, Ashley M. Pierce, Winston Luke, Xinrong Ren, Paul Kelley Nov 2016

Automated Calibration Of Atmospheric Oxidized Mercury Measurements, Seth Lyman, Colleen Jones, Trevor O'Neil, Tanner Allen, Matthieu Miller, Mae Sexauer Gustin, Ashley M. Pierce, Winston Luke, Xinrong Ren, Paul Kelley

USU Uintah Basin Faculty Publications

The atmosphere is an important reservoir for mercury pollution, and understanding of oxidation processes is essential to elucidating the fate of atmospheric mercury. Several recent studies have shown that a low bias exists in a widely applied method for atmospheric oxidized mercury measurements. We developed an automated, permeation tube-based calibrator for elemental and oxidized mercury, and we integrated this calibrator with atmospheric mercury instrumentation (Tekran 2537/1130/1135 speciation systems) in Reno, Nevada and at Mauna Loa Observatory, Hawaii, U.S.A. While the calibrator has limitations, it was able to routinely inject stable amounts of HgCl2 and HgBr2 into atmospheric mercury measurement systems …


Synchrony In A Boolean Network Of The L-Arabinose Operon In Escherichia Coli, Andy Jenkins, Matthew Macauley Nov 2016

Synchrony In A Boolean Network Of The L-Arabinose Operon In Escherichia Coli, Andy Jenkins, Matthew Macauley

Publications

The lactose operon in Escherichia coli was the first known gene regulatory network, and it is frequently used as a prototype for new modeling paradigms. Historically, many of these modeling frameworks use differential equations. More recently, Stigler and Veliz-Cuba proposed a Boolean network model that captures the bistability of the system and all of the biological steady states. In this paper, we model the well-known arabinose operon in E. coli with a Boolean network. This has several complex features not found in the lac operon, such as a protein that is both an activator and repressor, a DNA looping mechanism …


Perspectives On The Development Of A Local Food System: The Case Of Dayton, Ohio, Diana Cuy Castellanos, John C. Jones, Joanne Christaldi, Katherine A. Liutkus Nov 2016

Perspectives On The Development Of A Local Food System: The Case Of Dayton, Ohio, Diana Cuy Castellanos, John C. Jones, Joanne Christaldi, Katherine A. Liutkus

Health and Sport Science Faculty Publications

Multiple sectors play vital roles in a community’s development and maintenance of a sustainable local food system. This study explored the perceptions of twenty-two representatives from the civil society, public, and private sectors in Dayton, Ohio, about the development of the region’s local food system. The researchers employed grounded theory methodology for data collection and analysis. Core themes from the participants of each sector group emerged from the data and areas of convergence and divergence among groups were reported.


Csp And “Omics” Technology Applied On Versatile And Intelligent Portable Platform For Modeling Complex Bio-Medical Data, Florentin Smarandache, Luige Vladareanu, Mihaiela Iliescu, Hongbo Wang, Feng Yongfei, Victor Vladareanu Nov 2016

Csp And “Omics” Technology Applied On Versatile And Intelligent Portable Platform For Modeling Complex Bio-Medical Data, Florentin Smarandache, Luige Vladareanu, Mihaiela Iliescu, Hongbo Wang, Feng Yongfei, Victor Vladareanu

Branch Mathematics and Statistics Faculty and Staff Publications

This paper presents relevant aspects of the idea of using the digital medicine in cancer, so that to shape a viable strategy for creating and implementing an interactive digital platform, NEO-VIP, that should be the basic support to design the strategy for integration of basic, clinical and environmental research on neoplasia progression to cancer. The two main components of the VIPRO Platform are represented by the workstation “Engineering Station” for CPS (Cyber Physical System) and “omics” technology and by the “Graphical Station” for the development of a virtual mechatronic system environment and virtual reality for system components' motion. The NEO-VIP …


Climate, Soil And Land-Use Based Land Suitability Evaluation For Oil Palm Production In Ghana, Tiemen Rhebergen, Thomas Fairhurst, Shamie Zingore, Myles Fisher, Thomas Oberthür, Anthony Whitbread Nov 2016

Climate, Soil And Land-Use Based Land Suitability Evaluation For Oil Palm Production In Ghana, Tiemen Rhebergen, Thomas Fairhurst, Shamie Zingore, Myles Fisher, Thomas Oberthür, Anthony Whitbread

All Peer-Reviewed Publications

In the past decade, oil palm (Elaeis guineensis Jacq.) has become the world's most important oil crop. The large demand for palm oil has resulted in a rapid expansion of oil palm cultivation across the globe. Because of the dwindling availability of land in Southeast Asia, most expansion of the industry is expected in Central and South America and sub-Saharan Africa, where land with suitable agro-ecological conditions is available. Using Ghana as a case study, a method for evaluating areas that are both suitable and available for oil palm production is presented. Our assessment used spatial data and GIS techniques, …


The Potential Antioxidant And Anti-Inflammatory Effects Of Date Seed Powder In Rats, Fatima Theyab Saif Amer Ai Meqbaali Nov 2016

The Potential Antioxidant And Anti-Inflammatory Effects Of Date Seed Powder In Rats, Fatima Theyab Saif Amer Ai Meqbaali

Theses

Chronic diseases are among the main leading causes of mortality and morbidity in the United Arab Emirates (UAE). Oxidative stress (defined as an imbalance in the reactive oxygen species production/degradation ratio) in interaction with inflammation, has been highlighted as one major underlying mechanism in the development of these diseases. Due to their antioxidant and anti-inflammatory properties, polyphenols could prevent the development of chronic diseases. Interestingly, date seeds are particularly rich in such compounds. Nonetheless, an in vivo study aiming at studying and understanding antioxidant and anti-inflammatory effects of date seeds in serum and various organs is missing. Therefore, the present …