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Phosphorus And Potassium Fertilizer Application Strategies In Corn–Soybean Rotations, Timothy J. Boring, Kurt D. Thelen, James E. Board, Jason L. De Bruin, Chad D. Lee, Seth L. Naeve, William J. Ross, Wade A. Kent, Landon L. Ries Sep 2018

Phosphorus And Potassium Fertilizer Application Strategies In Corn–Soybean Rotations, Timothy J. Boring, Kurt D. Thelen, James E. Board, Jason L. De Bruin, Chad D. Lee, Seth L. Naeve, William J. Ross, Wade A. Kent, Landon L. Ries

Plant and Soil Sciences Faculty Publications

To determine if current university fertilizer rate and timing recommendations pose a limitation to high-yield corn (Zea mays subsp. mays) and soybean (Glycine max) production, this study compared annual Phosphorous (P) and Potassium (K) fertilizer applications to biennial fertilizer applications, applied at 1× and 2× recommended rates in corn–soybean rotations located in Minnesota (MN), Iowa (IA), Michigan (MI), Arkansas (AR), and Louisiana (LA). At locations with either soil test P or K in the sub-optimal range, corn grain yield was significantly increased with fertilizer application at five of sixteen site years, while soybean seed yield was significantly …


Particulate Metal Exposures Induce Plasma Metabolome Changes In A Commuter Panel Study, Chandresh N. Ladva, Rachel Golan, Donghai Liang, Roby Greenwald, Douglas I. Walker, Amit U. Raysoni, Vilinh Tran, Tianwei Yu, W. Dana Flanders, Gary W. Miller Sep 2018

Particulate Metal Exposures Induce Plasma Metabolome Changes In A Commuter Panel Study, Chandresh N. Ladva, Rachel Golan, Donghai Liang, Roby Greenwald, Douglas I. Walker, Amit U. Raysoni, Vilinh Tran, Tianwei Yu, W. Dana Flanders, Gary W. Miller

School of Earth, Environmental, & Marine Sciences Faculty Publications

Introduction

Advances in liquid chromatography-mass spectrometry (LC-MS) have enabled high-resolution metabolomics (HRM) to emerge as a sensitive tool for measuring environmental exposures and corresponding biological response. Using measurements collected as part of a large, panel-based study of car commuters, the current analysis examines in-vehicle air pollution concentrations, targeted inflammatory biomarker levels, and metabolomic profiles to trace potential metabolic perturbations associated with on-road traffic exposures.

Methods

A 60-person panel of adults participated in a crossover study, where each participant conducted a highway commute and randomized to either a side-street commute or clinic exposure session. In addition to in-vehicle exposure characterizations, participants …


The Assemblage Structure And Trophic Ecology Of A Deep-Pelagic Fish Family (Platytroctidae) In The Gulf Of Mexico, Michael Novotny Sep 2018

The Assemblage Structure And Trophic Ecology Of A Deep-Pelagic Fish Family (Platytroctidae) In The Gulf Of Mexico, Michael Novotny

HCNSO Student Theses and Dissertations

Members of the family Platytroctidae (tubeshoulders) are found throughout the meso- and bathypelagic waters of the World Ocean. Due to the lack of specimens collected globally, this taxon has received little attention, despite recent evidence suggesting its predominance in the bathypelagic biome. Prior to this study, only four species had been reported in the Gulf of Mexico’s (GoM) highly diverse deep-pelagic ecosystem. An extensive meso- and bathypelagic trawl series in the GoM allowed a detailed examination of this family, which included analyses of species composition, abundance, vertical distribution, sex ratios, and trophic ecology. A total of 16 species were collected, …


Comparison Of Multiple Imputation Methods For Categorical Survey Items With High Missing Rates: Application To The Family Life, Activity, Sun, Health And Eating (Flashe) Study, Benmei Liu, Erin Hennessy, April Oh, Laura A. Dwyer, Linda Nebeling Sep 2018

Comparison Of Multiple Imputation Methods For Categorical Survey Items With High Missing Rates: Application To The Family Life, Activity, Sun, Health And Eating (Flashe) Study, Benmei Liu, Erin Hennessy, April Oh, Laura A. Dwyer, Linda Nebeling

Journal of Modern Applied Statistical Methods

Two multiple imputation methods, the Sequential Regression Multivariate Imputation Algorithm and the Cox-Lannacchione Weighted Sequential Hotdeck, were examined and compared to impute highly missing categorical variables from the Family Life, Activity, Sun, Health and Eating (FLASHE) study. This paper describes the imputation approaches and results from the study.


New Market Opportunities And Consumer Heterogeneity In The U.S. Organic Food Market, Gwanseon Kim, Jun Ho Seok, Tyler B. Mark Sep 2018

New Market Opportunities And Consumer Heterogeneity In The U.S. Organic Food Market, Gwanseon Kim, Jun Ho Seok, Tyler B. Mark

Agricultural Economics Faculty Publications

This paper investigates what factors and characteristics of organic consumers affect annual organic food expenditure by using Nielsen’s consumer panel dataset from 2010 to 2014. To be specific, this paper explores new marketing opportunities by investigating organic consumer heterogeneity in different household income levels by utilizing the multilevel model. Findings in this study will contribute to the previous and existing literature in three-folds. First, we find that the organic consumers are more heterogeneous in the high-level of income groups (approximately above $60,000), as well as the low-income households between $35,000 and $45,000. This finding demonstrates that the income levels above …


The Effects Of Density Gradients On The Distribution And Behavior Of Copepods, Connor Cayson Aug 2018

The Effects Of Density Gradients On The Distribution And Behavior Of Copepods, Connor Cayson

Theses

Observations of fine-scale behavioral dynamics of zooplankton may shed insight into much larger-scale ecosystem patterns and phenomena. Some zooplankton, such as copepods, are known to aggregate near density gradients; however, it is not clear the extent to which density gradients alone affect copepod distribution and behavior, since these gradients are often associated with phytoplankton layers. In this study, we investigated the behavior of Calanus pacificus in response to salinity gradients through laboratory experiments observed with high-resolution video and analyzed using computational techniques. Image data were collected using two cameras recording continuously for a duration of 30 minutes or more, allowing …


P-Value Histograms: Inference And Diagnostics, Patrick Breheny, Arnold Stromberg, Joshua Lambert Aug 2018

P-Value Histograms: Inference And Diagnostics, Patrick Breheny, Arnold Stromberg, Joshua Lambert

Statistics Faculty Publications

It is increasingly common for experiments in biology and medicine to involve large numbers of hypothesis tests. A natural graphical method for visualizing these tests is to construct a histogram from the p-values of these tests. In this article, we examine the shapes, both regular and irregular, that these histograms can take on, as well as present simple inferential procedures that help to interpret the shapes in terms of diagnosing potential problems with the experiment. We examine potential causes of these problems in detail, and discuss potential remedies. Throughout, examples of irregular-looking p-value histograms are provided and based …


Factors Influencing Immunisation Schedule Adherence And Completion At The Regional Level In The Philippines, Paolo Miguel Manalang Vicerra Aug 2018

Factors Influencing Immunisation Schedule Adherence And Completion At The Regional Level In The Philippines, Paolo Miguel Manalang Vicerra

Kesmas

Penyebab utama kematian bayi sebagian besar dapat dicegah dan terdapat alasan baik dari sisi suplai maupun permintaan layanan kesehatan hal itu dapat terus berlangsung. Penelitian ini bertujuan memastikan faktor-faktor yang memengaruhi perilaku layanan kesehatan preventif imunisasi bayi di Filipina yang tepat waktu karena tingkat kelengkapan, atau kepatuhan, telah stabil dalam beberapa dekade terakhir. Metode yang digunakan adalah pembuatan model statistik di tingkat subnasional. Sampel berisi bayi yang lahir sebelum Survei Demografi dan Kesehatan Nasional Filipina tahun 2013 untuk menentukan kepatuhan yang tepat terhadap jadwal imunisasi yang dimandatkan oleh pemerintah. Hal ini melibatkan penggabungan 17 wilayah administratif negara ke tiga wilayah …


Husband’S Support For Their Wives In Antenatal Care Visit, Awalia Hanifah, Hadi Pratomo, Giang Hoang Aug 2018

Husband’S Support For Their Wives In Antenatal Care Visit, Awalia Hanifah, Hadi Pratomo, Giang Hoang

Kesmas

Di wilayah Puskesmas Cimanggis, Kota Depok, cakupan kunjungan antenatal pertama (K1) dan kunjungan ke-4 (K4) sebesar 99,4% (2013) dan 91% (2014). Dukungan suami ibu hamil merupakan salah satu faktor yang berperan penting dalam kunjungan antenatal pada ibu hamil. Penelitian ini bertujuan menilai faktor predisposisi, pemungkin dan penguat dari dukungan suami terhadap ANC istrinya dengan menggunakan pendekatan kualitatif dengan desain Rapid Assessment Procedure. Lima suami dan istrinya yang sedang hamil dipilih sebagai informan serta dua bidan puskesmas sebagai informan kunci. Analisis data menggunakan matriks data kualitatif dan teknik analisis tematik. Hasil penelitian menunjukkan bahwa faktor predisposisi, pemungkin dan penguat dari suami …


Influential Host Factors To The Incidence Of Hiv/Aids In Key Populations In Pati District, Dwi Murtono, Puguh Riyanto, Zahroh Shaluhiyah Aug 2018

Influential Host Factors To The Incidence Of Hiv/Aids In Key Populations In Pati District, Dwi Murtono, Puguh Riyanto, Zahroh Shaluhiyah

Kesmas

Human Immunodeficiency Virus (HIV) dan Acquired Immune Deficiency Syndrome (AIDS) merupakan penyakit berbahaya di dunia yang salah satu metode penularannya adalah melalui hubungan seksual. Penelitian ini bertujuan menjelaskan faktor-faktor yang berpengaruh terhadap kejadian HIV/AIDS pada populasi kunci. Penelitian dilakukan dari bulan Maret sampai September 2016. Penelitian analitik observasional dengan rancangan kasus kontrol pada populasi kunci di Kabupaten Pati. Kasus sebanyak 53 pasien positif HIV/AIDS, sedangkan kontrol sebanyak 53 pasien negative HIV/AIDS.Pengambilan sampel menggunakan teknik consecutive sampling. Data diperoleh dari riwayat medis dan wawancara kuesioner. Penelitian ini menggunakan uji kai kuadrat pada analisis bivariat dan regresi logistik ganda pada analisis multivariat. …


Web-Based Application To Support Physical Fitness Information Of Elderly People, Yudhy Dharmawan, Suroto Suroto, Priguna Septia Putra Aug 2018

Web-Based Application To Support Physical Fitness Information Of Elderly People, Yudhy Dharmawan, Suroto Suroto, Priguna Septia Putra

Kesmas

Penduduk lanjut usia (lansia) semakin banyak seiring meningkatnya usia harapan hidup. Banyak upaya yang harus dilakukan untuk mencegah kesakitan di lansia, salah satunya dari aspek preventif dengan menjaga kebugaran para lansia. Untuk memonitor status kebugaran lansia, maka diperlukan aplikasi pemantauan kebugaran jasmani berbasis teknologi web karena tidak ada sistem yang merekam data kebugaran para lansia. Aplikasi ini ditujukan untuk merekam data kebugaran jasmani para lansia untuk merekomendasikan gym yang sesuai berdasarkan kondisi kesehatan yang dapat diakses di mana saja. Aplikasi ini dibuat dengan bahasa pemrograman PHP dan MYSQL sebagai pengolahan basis data yang dilengkapi dengan grafik untuk memantau kebugaran jasmaninya. …


Unsafe Behavior Of Workers In Rotary Lathe Section In One Of The Plywood Industries In East Kalimantan, Iwan Muhamad Ramdan, Dyyka Indah Wijayanti Aug 2018

Unsafe Behavior Of Workers In Rotary Lathe Section In One Of The Plywood Industries In East Kalimantan, Iwan Muhamad Ramdan, Dyyka Indah Wijayanti

Kesmas

Kecelakaan kerja dan penyakit akibat kerja masih menjadi masalah kesehatan dunia, dua faktor utama penyebabnya adalah perilaku dan kondisi lingkungan kerja yang tidak aman. Penelitian sebelumnya membuktikan penyebab utamanya adalah faktor perilaku yang tidak aman. Penelitian ini bertujuan menganalisis faktor-faktor yang berhubungan dengan perilaku tidak aman dalam bekerja pada tenaga kerja di PT IAW dan menganalisis faktor yang paling berpengaruh. Penelitian potong lintang dilakukan pada bulan Juli sampai Agustus 2016 terhadap 104 sampel penelitian. Variabel bebas terdiri dari persepsi, komunikasi, pengawasan, ketersediaan alat pelindung diri (APD), pelatihan dan suhu lingkungan kerja. Variabel terikat adalah perilaku tidak aman. Analisis data menggunakan …


Direct Experience With Cervical Cancer Patient, Husband Support, And Self-Perception As Determinant Factors Of Women’S Desire To Take Via Screening Test, Nur Anisah Rahmawati, Linda Dewanti Aug 2018

Direct Experience With Cervical Cancer Patient, Husband Support, And Self-Perception As Determinant Factors Of Women’S Desire To Take Via Screening Test, Nur Anisah Rahmawati, Linda Dewanti

Kesmas

Kanker serviks menyebabkan 10.3% kematian pada perempuan di Indonesia. Inspeksi visual asam asetat (IVA) telah digunakan untuk program skrining sejak tahun 2014 tetapi hanya 2,45 % perempuan yang melakukan pemeriksaan pada tahun 2015. Di tempat penelitian, cakupan skrining metode IVA kurang dari 1%. Penelitian sebelumnya menyebutkan faktor psikososial sebagai satu faktor penting, tetapi sedikit penelitian yang menganalisis peran dukungan suami dan pengalaman langsung dengan penderita kanker serviks. Penelitian ini bertujuan mempelajari hubungan antara pengalaman langsung dengan penderita kanker serviks, dukungan suami, persepsi diri dan keinginan perempuan melakukan skrining IVA. Penelitian potong lintang dilakukan secara acak pada perempuan berusia 25-55 tahun …


The Implementation Of Documentation By Midwives In Pekanbaru, Wan Anita Aug 2018

The Implementation Of Documentation By Midwives In Pekanbaru, Wan Anita

Kesmas

Dokumentasi kebidanan adalah suatu bukti pencatatan dan pelaporan yang dimiliki oleh bidan dalam melakukan catatan perawatan yang berguna untuk kepentingan pasien, bidan, dan tim kesehatan. Pendokumentasian dapat diterapkan dengan metode Subjektif, Objektif, Analisa dan Perencanaan (SOAP). Penelitian ini bertujuan mengetahui faktor-faktor yang berhubungan dengan pelaksanaan dokumentasi SOAP oleh bidan di Kota Pekanbaru tahun 2016. Penelitian bersifat kuantitatif analitik observasional dengan desain penelitian potong lintang analitik. Sampel penelitian adalah seluruh populasi bidan yang praktik mandiri atau di rumah bersalin di Kota Pekanbaru dengan jumlah sampel sebanyak 191 bidan yang diambil dengan prosedur systematic random sampling. Data dikumpulkan melalui wawancara langsung dengan …


Adolescent’S Knowledge And Skill To Refuse Drugs, Lucky Herawati, Johan Arief Budiman, Haryono Haryono Aug 2018

Adolescent’S Knowledge And Skill To Refuse Drugs, Lucky Herawati, Johan Arief Budiman, Haryono Haryono

Kesmas

Berbagai upaya telah dilakukan untuk mencegah remaja dari penggunaan narkoba, kendatipun evaluasi pengetahuan dan keterampilan remaja menolak narkoba belum pernah dilakukan. Penelitian ini dilakukan pada 300 remaja, siswa kelas 7 atau setara usia 12-15 tahun di dua kota di Provinsi Daerah Istimewa Yogyakarta. Penelitian analitik bertujuan mengetahui gambaran pengetahuan, keterampilan remaja menolak narkoba, dan hubungan keduanya dengan karakteristik remaja. Variabel yang diteliti adalah pengetahuan remaja tentang narkoba, keterampilan menolak narkoba, dan karakteristik remaja, yang dikumpulkan dengan menggunakan kuesioner (self-reported questionnaire). Data dianalisis dengan uji korelasi Pearson dan Spearman rho, dengan tingkat signifikansi 95 persen. Hasil penelitian menunjukkan bahwa rata-rata nilai …


Transcriptional Response Of Honey Bee (Apis Mellifera) To Differential Nutritional Status And Nosema Infection, Farida Azzouz-Olden, Arthur G. Hunt, Gloria Degrandi-Hoffman Aug 2018

Transcriptional Response Of Honey Bee (Apis Mellifera) To Differential Nutritional Status And Nosema Infection, Farida Azzouz-Olden, Arthur G. Hunt, Gloria Degrandi-Hoffman

Plant and Soil Sciences Faculty Publications

Background: Bees are confronting several environmental challenges, including the intermingled effects of malnutrition and disease. Intuitively, pollen is the healthiest nutritional choice, however, commercial substitutes, such as Bee-Pro and MegaBee, are widely used. Herein we examined how feeding natural and artificial diets shapes transcription in the abdomen of the honey bee, and how transcription shifts in combination with Nosema parasitism.

Results: Gene ontology enrichment revealed that, compared with poor diet (carbohydrates [C]), bees fed pollen (P > C), Bee-Pro (B > C), and MegaBee (M > C) showed a broad upregulation of metabolic processes, especially lipids; however, pollen feeding promoted more functions, and …


Optimization Of Dna Isolation And Purification Methods For Molecular Genetic Analysis Of Uncultivated Microorganisms Of Cows Rumen, L. Ilina,, G. Laptev,, E. Yildirim, Aug 2018

Optimization Of Dna Isolation And Purification Methods For Molecular Genetic Analysis Of Uncultivated Microorganisms Of Cows Rumen, L. Ilina,, G. Laptev,, E. Yildirim,

Scientific journal of the Fergana State University

This work optimizes the methods of isolation and purification of the ruminal microorganisms’ total DNA in clinically healthy cows


Optimization Of Dna Isolation And Purification Methods For Molecular Genetic Analysis Of Uncultivated Microorganisms Of Cows Rumen, L. Ilina,, G. Laptev,, E. Yildirim, Aug 2018

Optimization Of Dna Isolation And Purification Methods For Molecular Genetic Analysis Of Uncultivated Microorganisms Of Cows Rumen, L. Ilina,, G. Laptev,, E. Yildirim,

Scientific journal of the Fergana State University

This work optimizes the methods of isolation and purification of the ruminal microorganisms’ total DNA in clinically healthy cows


Economics Of Managing Loblolly Pine Plantations For Increased Wildlife Biodiversity, Melissa Griffith Aug 2018

Economics Of Managing Loblolly Pine Plantations For Increased Wildlife Biodiversity, Melissa Griffith

Electronic Theses and Dissertations

The goal of this thesis was to identify the differences between the costs incurred and revenues gained from managing loblolly pine (Pinus taeda) plantations in East Texas for strictly timber production or a combination of timber production and wildlife biodiversity. Management regimes evaluated had varying planting densities, thinning frequency and intensities, prescribed burn intervals, and site indices. Economic analyses used to evaluate management regimes over a range of nonindustrial private landowner (NIPF) alternative rates of return (ARRs) and site indexes were net present worth, land expectation value, and equal annual annuity. These economic analyses demonstrated that altering management …


Dietary Inflammatory Index And Biomarkers Of Lipoprotein Metabolism, Inflammation And Glucose Homeostasis In Adults, Catherine Phillips, Nitin Shivappa, James R. Hébert, Ivan Perry Aug 2018

Dietary Inflammatory Index And Biomarkers Of Lipoprotein Metabolism, Inflammation And Glucose Homeostasis In Adults, Catherine Phillips, Nitin Shivappa, James R. Hébert, Ivan Perry

Faculty Publications

Accumulating evidence identifies diet and inflammation as potential mechanisms contributing to cardiometabolic risk. However, inconsistent reports regarding dietary inflammatory potential, biomarkers of cardiometabolic health and metabolic syndrome (MetS) risk exist. Our objective was to examine the relationships between a food frequency questionnaire (FFQ)-derived dietary inflammatory index (DII®), biomarkers of lipoprotein metabolism, inflammation and glucose homeostasis and MetS risk in a cross-sectional sample of 1992 adults. Energy-adjusted DII (E-DII) scores derived from an FFQ were calculated. Lipoprotein particle size and subclass concentrations were measured using nuclear magnetic resonance (NMR) spectroscopy. Serum acute-phase reactants, adipocytokines, pro-inflammatory cytokines and white blood cell (WBC) …


Analysis Of Temperature And Salinity Effects On Growth And Mortality Of Oysters (Crassostrea Virginica) In Louisiana, Troy Sehlinger Aug 2018

Analysis Of Temperature And Salinity Effects On Growth And Mortality Of Oysters (Crassostrea Virginica) In Louisiana, Troy Sehlinger

LSU New Orleans Theses and Dissertations

Salinity (S) and temperature (T) control every facet of the eastern oyster (Crassostrea virginica) life cycle, principally reproduction, development, growth, and mortality. Previous studies conducted in in the Breton Sound (BR) and Barataria (BA) estuaries have reported differences in growth and mortality rates between the basins. In the present study, environmental conditions were synchronized to compare growth and mortality rates between basins at similar combinations of T and S. Results indicate that when T and S are the same (synchronized), seasonal oyster growth and mortality rates differ between BR and BA. Seasonal analyses revealed that as salinities increased …


Quantifying Plant Soluble Protein And Digestible Carbohydrate Content, Using Corn (Zea Mays) As An Exemplar, Carrie A. Deans, Gregory A. Sword, Paul A. Lenhart, Eric Burkness, William D. Hutchison, Spencer T. Behmer Aug 2018

Quantifying Plant Soluble Protein And Digestible Carbohydrate Content, Using Corn (Zea Mays) As An Exemplar, Carrie A. Deans, Gregory A. Sword, Paul A. Lenhart, Eric Burkness, William D. Hutchison, Spencer T. Behmer

Entomology Faculty Publications

Elemental data are commonly used to infer plant quality as a resource to herbivores. However, the ubiquity of carbon in biomolecules, the presence of nitrogen-containing plant defensive compounds, and variation in species-specific correlations between nitrogen and plant protein content all limit the accuracy of these inferences. Additionally, research focused on plant and/or herbivore physiology require a level of accuracy that is not achieved using generalized correlations. The methods presented here offer researchers a clear and rapid protocol for directly measuring plant soluble proteins and digestible carbohydrates, the two plant macronutrients most closely tied to animal physiological performance. The protocols combine …


Quercetin Inhibits Glucose Transport By Binding To An Exofacial Site On Glut1, Kathryn E. Hamilton, Janelle F. Rekman, Leesha K. Gunnink, Brianna M. Busscher Aug 2018

Quercetin Inhibits Glucose Transport By Binding To An Exofacial Site On Glut1, Kathryn E. Hamilton, Janelle F. Rekman, Leesha K. Gunnink, Brianna M. Busscher

University Faculty Publications and Creative Works

Quercetin, a common dietary flavone, is a competitive inhibitor of glucose uptake and is also thought to be transported into cells by GLUT1. In this study, we confirm that quercetin is a competitive inhibitor of GLUT1 and also demonstrate that newly synthesized compounds, WZB-117 and BAY-876 are robust inhibitors of GLUT1 in L929 cells. To measure quercetin interaction with L929 cells, we develop a new fluorescent assay using flow cytometry. The binding of quercetin and its inhibitory effects on 2-deoxyglucose (2DG) uptake showed nearly identical dose dependent effects, with both having maximum effects between 50 and 100 μM and similar …


Generalized Spatiotemporal Modeling And Causal Inference For Assessing Treatment Effects For Multiple Groups For Ordinal Outcome., Soutik Ghosal Aug 2018

Generalized Spatiotemporal Modeling And Causal Inference For Assessing Treatment Effects For Multiple Groups For Ordinal Outcome., Soutik Ghosal

Electronic Theses and Dissertations

This dissertation consists of three projects and can be categorized in two broad research areas: generalized spatiotemporal modeling and causal inference based on observational data. In the first project, I introduce a Bayesian hierarchical mixed effect hurdle model with a nested random effect structure to model the count for primary care providers and understand their spatial and temporal variation. This study further enables us to identify the health professional shortage areas and the possible impacting factors. In the second project, I have unified popular parametric and nonparametric propensity score-based methods to assess the treatment effect of multiple groups for ordinal …


Bayesian Analytical Approaches For Metabolomics : A Novel Method For Molecular Structure-Informed Metabolite Interaction Modeling, A Novel Diagnostic Model For Differentiating Myocardial Infarction Type, And Approaches For Compound Identification Given Mass Spectrometry Data., Patrick J. Trainor Aug 2018

Bayesian Analytical Approaches For Metabolomics : A Novel Method For Molecular Structure-Informed Metabolite Interaction Modeling, A Novel Diagnostic Model For Differentiating Myocardial Infarction Type, And Approaches For Compound Identification Given Mass Spectrometry Data., Patrick J. Trainor

Electronic Theses and Dissertations

Metabolomics, the study of small molecules in biological systems, has enjoyed great success in enabling researchers to examine disease-associated metabolic dysregulation and has been utilized for the discovery biomarkers of disease and phenotypic states. In spite of recent technological advances in the analytical platforms utilized in metabolomics and the proliferation of tools for the analysis of metabolomics data, significant challenges in metabolomics data analyses remain. In this dissertation, we present three of these challenges and Bayesian methodological solutions for each. In the first part we develop a new methodology to serve a basis for making higher order inferences in metabolomics, …


Seasonal Differences In Trace Element Concentrations And Distribution In Spartina Alterniflora Root Tissue, Huan Feng, Yu Qian, J. Kirk Cochran, Qingzhi Zhu, Christina Heilbrun, Li Li, Wen Hu, Hanfei Yan, Xiaojing Huang, Mingyuan Ge, Evgeny Nazareski, Yong S. Chu, Shinjae Yoo, Xuebin Zhang, Chang Jun Liu Aug 2018

Seasonal Differences In Trace Element Concentrations And Distribution In Spartina Alterniflora Root Tissue, Huan Feng, Yu Qian, J. Kirk Cochran, Qingzhi Zhu, Christina Heilbrun, Li Li, Wen Hu, Hanfei Yan, Xiaojing Huang, Mingyuan Ge, Evgeny Nazareski, Yong S. Chu, Shinjae Yoo, Xuebin Zhang, Chang Jun Liu

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

The present study uses nanometer-scale synchrotron X-ray nanofluorescence to investigate season differences in concentrations and distributions of major (Ca, K, S and P) and trace elements (As, Cr, Cu, Fe and Zn) in the root system of Spartina alterniflora collected from Jamaica Bay, New York, in April and September 2015. The root samples were cross-sectioned at a thickness of 10 μm. Selected areas in the root epidermis and endodermis were mapped with a sampling resolution of 100 and 200 nm, varying with the mapping areas. The results indicate that trace element concentrations in the epidermis and endodermis vary among the …


Separation, Detection, And Quantitation Of Underivatized Carbohydrates Using Liquid Chromatography- Electrospray Ionization-Triple Quadrupole- Tandem Mass Spectrometry, Jonathan B. Thacker Aug 2018

Separation, Detection, And Quantitation Of Underivatized Carbohydrates Using Liquid Chromatography- Electrospray Ionization-Triple Quadrupole- Tandem Mass Spectrometry, Jonathan B. Thacker

Chemistry & Biochemistry Dissertations - Archive

Carbohydrate analysis has many important implications in health, consumer products, and industrial processes. Among many possible analytical techniques for their analysis, mass spectrometry (MS) is an attractive approach, offering high sensitivity and specificity. In particular, electrospray ionization (ESI)-MS affords several advantages over other ionization techniques: the ability for direct coupling with upstream chemical separation techniques, its suitability for quantitation, and its compatibility with relatively inexpensive quadrupole mass analyzers for the analysis of high molecular weight compounds. However, the sensitivity of ESI-MS towards carbohydrates tends to be much less than for other classes of compounds, such as peptides. This is due …


Toxic Effects Of Lead Disposal In Water: An Analysis Of Tri Facility Releases, Patrick Koval Aug 2018

Toxic Effects Of Lead Disposal In Water: An Analysis Of Tri Facility Releases, Patrick Koval

Economics Department Working Papers

Using county-level TRI data from 2003 to 2016, I find evidence that lead emissions in water adversely affect birth weights within the emitting county, especially with respect to the percentage of births considered low birth weight within that county (less than 2,500 grams). I find that a one percent increase in lead emissions per square mile increases the proportion of low birth weights by 0.27 percentage points. For a county with an average number of births in a particular year, this one percent increase in lead per square mile translates to an additional $475,000 in hospitalization costs from complications with …


A Comparison Of Vnir And Mir Spectroscopy For Predicting Various Soil Properties, Joshua R. Gates Aug 2018

A Comparison Of Vnir And Mir Spectroscopy For Predicting Various Soil Properties, Joshua R. Gates

School of Natural Resources: Dissertations, Theses, and Student Research

Soil plays an important role in our daily lives, namely producing food, cleaning water and storing carbon. The ability to rapidly and cost-effectively quantify the various components of soils can help us understand and better manage this important resource. This study aims to compare the ability of visible near-infrared (VNIR) spectroscopy and mid-infrared (MIR) spectroscopy to quickly and accurately predict various important soil properties (electrical conductivity, soil pH, cation exchange capacity, exchangeable cations, phosphorus, carbon, beta-glucosidase enzyme activity and nitrogen). Prediction models were developed using partial least squares regression (PLSR) techniques. Three different calibration sampling methods were tested along with …


Advancing Risk Assessment: Mechanistic Dose-Response Modelling Of Listeria Monocytogenes Infection In Human Populations, Ashrafur Rahman, Daniel Munther, Aamir Fazil, Ben Smith, Jianhong Wu Aug 2018

Advancing Risk Assessment: Mechanistic Dose-Response Modelling Of Listeria Monocytogenes Infection In Human Populations, Ashrafur Rahman, Daniel Munther, Aamir Fazil, Ben Smith, Jianhong Wu

Mathematics and Statistics Faculty Publications

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited. The utility of characterizing the effects of strain variation and individual/subgroup susceptibility on dose-response outcomes has motivated the search for new approaches beyond the popular use of the exponential dose-response model for listeriosis. While descriptive models can account for such variation, they have limited power to extrapolate beyond the details of particular outbreaks. By contrast, this study exhibits dose-response relationships from a mechanistic basis, quantifying key biological factors involved in pathogen-host dynamics. An …