Digital Commons Network^™

Kinetic Study For The Effect Of New Inhibitors On The Activity Of Purified Gpt From Blood Of Cardiovascular Patients, Firas Maher

Karbala International Journal of Modern Science

In this study several biochemical parameters for cardiovascular patients have been measured CK-MB ,LDH ,GPT and GOT in addition to lipid profile , MDA ,Vitamin C and Vitamin E . New derivatives of ascorbic acid have been synthesized and tested to inhibit the purified GPT from the blood of cardiovascular patients Glutamate pyruvate transaminase (GPT) was purified from cardiovascular patients using ammonium sulphate salt for precipitation then dialysed using 0.1 M Tris-HCL buffer pH7.8 , then filtrated by gel filtration chromatography using Sephadex G-100 , followed by electrophoresis using poly acrylamide – bis acrylamide and sodium dodecyl sulphate (SDS). Derivatives …

Identifying Depression In The National Health And Nutrition Examination Survey Data Using A Deep Learning Algorithm, Jihoon Oh, Kyongsik Yun, Uri Maoz, Tae-Suk Kim, Jeong-Ho Chae

Psychology Faculty Articles and Research

Background

As depression is the leading cause of disability worldwide, large-scale surveys have been conducted to establish the occurrence and risk factors of depression. However, accurately estimating epidemiological factors leading up to depression has remained challenging. Deep-learning algorithms can be applied to assess the factors leading up to prevalence and clinical manifestations of depression.

Methods

Customized deep-neural-network and machine-learning classifiers were assessed using survey data from 19,725 participants from the NHANES database (from 1999 through 2014) and 4949 from the South Korea NHANES (K-NHANES) database in 2014.

Results

A deep-learning algorithm showed area under the receiver operating characteristic curve (AUCs) …

Renewable Energy Access And Resilience In Urban Developing Areas: Distributed Solar Networks And Peer-To-Peer Energy Trading In Puerto Rico, Pascale Bronder

Harvey M. Applebaum ’59 Award

This senior essay under the Environmental Studies major at Yale University explores the environmental and social benefits of applying innovative technology to the energy sector. Three types of energy networks are analyzed, focusing on the use of distributed energy and peer to peer energy trading on a blockchain platform. The benefits of distributed renewable energy networks can most strongly be applied to locations in need of more reliable, resilient, and cost-effective electricity. Puerto Rico is a case study. Methods include analysis of U.S. Energy Information Administration and Census Bureau data as well as personal interviews with Puerto Rican energy developers. …

Comparative Efficacy Of Novel Endolysins In Queso Fresco, Daniella Smith, Maxwell J. Holle, Dr. Michael Miller

PRECS student projects

Listeria monocytogenes is problematic for the manufacturing, storage, and consumption of ready-to-eat foods. This bacterium may cause listeriosis upon consumption often with deadly complications. Queso Fresco (QF), a pasteurized Hispanic-style fresh cheese (HSFC), has been shown to support the growth of L. monocytogenes. QF is the most widely produced and implicated HSFC in the U.S., representing a significant health hazard to at risk populations such as infants, pregnant women, elderly, and the immunocompromised. The objective of this research project is to evaluate the efficacy of ten novel antimicrobial endolysins in combatting L. monocytogenes contamination in a miniaturized lab-scale queso fresco …

Resident Perceptions Of Black Bear Management In South Central Kentucky, Hung-Ling (Stella) Liu, Michael J. Bradley, I-Chun Nicky Wu, James N. Maples

Health and Nutritional Sciences Faculty Publications

The growth and sprawl of the American black bear (Ursus americanus ) population have been observed and monitored in the past two decades, especially in south-central Kentucky. To better manage human-black bear interaction and develop informed policy and best practices, the current study sought to 1) understand south-central Kentucky residents’ current knowledge of and previous experience with black bears, 2) investigate residents’ attitudes toward black bears and regulated hunting in wildlife management; and 3) identify residents’ level of acceptance of various black bear related management actions in south-central Kentucky. From February to April 2017, residents of London and Stearns districts …

Why Iq Test Scores Are Slightly Decreasing: Possible System-Based Explanation For The Reversed Flynn Effect, Griselda Acosta, Eric Smith, Vladik Kreinovich

Departmental Technical Reports (CS)

Researchers who monitor the average intelligence of human population have reasonably recently made an unexpected observation: that after many decades in which this level was constantly growing (this is known as the Flynn effect), at present, this level has started decreasing again. In this paper, we show that this reversed Flynn effect can be, in principle, explained in general system-based terms: namely, it is similar to the fact that a control system usually overshoots before stabilizing at the desired level. A similar idea may explain another unexpected observation -- that the Universe's expansion rate, which was supposed to be decreasing, …

Mad Scientist Club | Experiments, Nora Husein

Honors Program: Expanded Learning Clubs

After school club that teaches the basics of different branches of science through hands-on activities and experiments.

Lipid Biomarkers Of Bering And Chukchi Sea Euphausiids And Their Application To Diet History, Rachel L. Pleuthner

OES Theses and Dissertations

In the eastern Bering Sea, Thysanoessa raschii are the most abundant krill species and a keystone trophic member that serve as both an important grazer and link to upper level consumers. In this system krill experience large annual variation in food resources, especially during ice advance and retreat; multiple lipid classes are used to temper the effects of those fluctuations, as well as to fuel reproduction and growth. Two shipboard feeding experiments that occurred during late spring and early summer of 2010, respectively, monitored the lipid retention in adult T. raschii and examined the fluctuation of specific lipid biomarkers under …

Estimation Problems For Pooled Data, Xichen Mou

Theses and Dissertations

In epidemiological applications, individual specimens (e.g., blood, urine, etc.) are often pooled together to detect the presence of disease or to measure the concentration level of a specific biomarker. Due to the advantage of cost efficiency, pooled data are also seen in diverse areas such as genetics, animal ecology, and environmental science. With pooled data, individual observations are masked and new statistical methods are needed to estimate characteristics such as disease prevalence, the underlying density function of a biomarker, etc. We focus on three estimation problems for pooled data. Chapters 2 and 3 propose nonparametric estimators for the density function …

Potassium Fertilization Effects On Yield For Wheat, Soybean, And Corn Grown In Coastal Plain Soils, Renada Davis

Theses and Dissertations

A study conducted on wheat, soybean, and corn crops was designed to assess the effect of potassium fertilization based on current potassium (K) fertilizer recommendations on crop yield, soil K levels, and plant tissue K concentration. The objectives of this study were to 1) evaluate the effect K fertilization has on crop yield; 2) To assess soil K levels through the duration of the experiment and the effect fertilization may have on soil K levels; and 3) to evaluate the effect of fertilization on plant tissue K concentrations. There was no statistical difference in yields between plots treated with the …

The Distribution And Biogeochemistry Of Subtropical Intertidal Microbial Mats, Bert D. Anderson

USF Tampa Graduate Theses and Dissertations

Microbial mats have played an important role in the carbon (C) and nutrient cycles since the Archean Eon and modern mats are important contributors to the biogeochemistry of intertidal wetlands. Microbial mats are flat assemblages of microbes that are currently found in many unvegetated habitats globally. Intertidal salt pans are a common habitat for microbial mats, however little is known about the distribution of microbial mats within the intertidal landscape. Understanding the spatial distribution of microbial mats is critical to developing quantitative estimates of the impacts of microbial mats on their ecosystems. We photographically measured the presence and density of …

Habitat Suitability Index Model Of The Florida Sandhill Crane (Grus Canadensis Pratensis) In West-Central Florida, Courtney E. Buck

USF Tampa Graduate Theses and Dissertations

The Florida Sandhill Crane (Grus canadensis pratensis) is a state threatened endemic subspecies of the Sandhill Crane (Nesbitt & Tacha, 1997). With a population that was estimated at a maximum of 5,000 individuals in 2003 (Nesbitt & Hatchitt, 2008), it is imperative to identify potentially viable habitats, as Florida is rapidly developing. This research develops a Habitat Suitability Index model to determine unsuitable to optimally suitable habitat locations throughout west-central Florida. To do so, six suitability variables based on the crane’s life history were evaluated: Potential nesting area, immediate nesting area, wetland coverage, foraging area, brooding area, and road proximity. …

Use Of Amulet In Behavioral Change For Geriatric Obesity Management, John A. Batsis, Alexandra B. Zagaria, Ryan J. Halter, George G. Boateng, Patrick Proctor, Stephen J. Bartels, David Kotz

Dartmouth Scholarship

Background: Obesity in older adults is a significant public health concern. Weight-loss interventions are known to improve physical function but risk the development of sarcopenia. Mobile health devices have the potential to augment existing interventions and, if designed accordingly, could improve one’s physical activity and strength in routine physical activity interventions.

Methods and results: We present Amulet, a mobile health device that has the capability of engaging patients in physical activity. The purpose of this article is to discuss the development of applications that are tailored to older adults with obesity, with the intention to engage and improve their health. …

Dietary Inflammatory Index, Dietary Non-Enzymatic Antioxidant Capacity, And Colorectal And Breast Cancer Risk(Mcc-Spain Study), Mireia Obón-Santacana, Dora Romaguera, Esther Gracia-Lavedan, Amaia Molinuevo, Esther Molina-Montes, Nitin Shivappa, James R. Hébert, Adonia Tardón, Gemma Castaño-Vinyals, Ferran Moratalla, Elisabet Guinó, Rafael Marcos-Gragera, Mikel Azpiri Leire Gil, Rocío Olmedo-Requena, Macarena Lozano-Lorca, Juan Alguacil, Tania Fernández-Villa, Vicente Martín, Antonio J. Molina, María Ederra, Beatriz Perez, Nuria Aragonés, Adela Castello, José Mª Huerta, Trinidad Dierssen-Sotos, Ana Molina-Barceló, Marina Pollán, Manolis Kogevinas, Victor Moreno, Pilar Amiano

Faculty Publications

Inflammation and antioxidant capacity have been associated with colorectal and breast cancer. We computed the dietary inflammatory index (DII®), and the total dietary non-enzymatic antioxidant capacity (NEAC) and associated them with colorectal and breast cancer risk in the population-based multi case-control study in Spain (MCC-Spain). We included 1852 colorectal cancer and 1567 breast cancer cases, and 3447 and 1486 population controls, respectively. DII score and NEAC were derived using data from a semi-quantitative validated food frequency questionnaire. Unconditional logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (95%CI) for energy-adjusted DII (E-DII), and a score …

Dietary Inflammatory Index, Dietary Non-Enzymatic Antioxidant Capacity, And Colorectal And Breast Cancer Risk (Mcc-Spain Study), Mireia Obon-Santacana, Dora Romaguera, Esther Gracia-Lavedan, Amaia Molinuevo, Esther Molina-Montes, Nitin Shivappa, James R. Hébert, Adonina Tardon, Gemma Castano-Vinyals, Ferran Moratalla, Elisabet Guino, Rafael Marcos-Gragera, Mikel Azpiri, Leire Gil, Rocio Olmedo-Requena, Macarena Lozano-Lorca, Juan Alguacil, Tania Fernandez-Villa, Vicente Martin, Antonio J. Molina, Maria Ederra, Conchi Moreno-Iribas, Beatriz Perez, Nuria Aragones

Faculty Publications

Inflammation and antioxidant capacity have been associated with colorectal and breast cancer. We computed the dietary inflammatory index (DII^®), and the total dietary non-enzymatic antioxidant capacity (NEAC) and associated them with colorectal and breast cancer risk in the population-based multi case-control study in Spain (MCC-Spain). We included 1852 colorectal cancer and 1567 breast cancer cases, and 3447 and 1486 population controls, respectively. DII score and NEAC were derived using data from a semi-quantitative validated food frequency questionnaire. Unconditional logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (95%CI) for energy-adjusted DII (E-DII), and …

Assay Of Vitamin B6 (Pyridoxine Hydrochloride) Utilizing Isocratic Reversed Phase High Performance Liquid Chromatography, Ronald Bartzatt, Purnima Gajmer, Mai Han Cassandra Nguyen, Alexndra My-Hanh Tran

Chemistry Faculty Publications

Aims: To demonstrate an analysis for vitamin B6 from commercial aqueous nutritional drinks and solid tablets, utilizing isocratic conditions with high performance liquid chromatography (HPLC) and UV detection at 290 nm. Study Design: Vitamin B6 in the form of pyridoxine hydrochloride is assayed by HPLC from various samples. Place and Duration of Study: Department of Chemistry, Durham Science Center, University of Nebraska, Omaha Nebraska from May to August 2016. Methodology: Utilizing a reversed-phase C-18 column with eluent solvent (19% ethanol, 77% water, 4% acetic acid), the samples were prepared in sample solvent (19% ethanol, 81% distilled water). Detection of vitamin …

Ocean Acidification Refugia In Variable Environments, Lydia Kapsenberg, Tyler Cyronak

Marine & Environmental Sciences Faculty Articles

Climate change refugia in the terrestrial biosphere are areas where species are protected from global environmental change and arise from natural heterogeneity in landscapes and climate. Within the marine realm, ocean acidification, or the global decline in seawater pH, remains a pervasive threat to organisms and ecosystems. Natural variability in seawater carbon dioxide (CO₂) chemistry, however, presents an opportunity to identify ocean acidification refugia (OAR) for marine species. Here, we review the literature to examine the impacts of variable CO₂ chemistry on biological responses to ocean acidification and develop a framework of definitions and criteria that connects …

Consumption Of Black Raspberries Altered The Composition Of The Fecal Microbiome In Mice Fed A Western Type Diet (Or04-01-19), Abby D. Benninghoff, Sumira Phatak, Korry Hintze

Chemistry and Biochemistry Faculty Publications

Dietary strategies to reduce colonic inflammation and promote gut homeostasis may markedly reduce the risk of colitis-associated colorectal cancer. Previously, we showed that dietary supplementation with black raspberries significantly suppressed colitis and colon tumorigenesis promoted by the consumption a Western type diet in mice. In this study, our goal was to assess the impact of consumption of the TWD with and without black raspberry supplementation on the composition of the fecal microbiome over the course of disease development.

Dietary Inflammatory Index And Sleep Quality In Southern Italian Adults, Justyna Godos, Raffaele Ferri, Filippo Caraci, Filomena I. I. Cosentino, Sabrina Castellano, Nitin Shivappa, James R. Hébert, Fabio Galvano, Giuseppe Grosso

Faculty Publications

Background: Current evidence supports the central role of a subclinical, low-grade inflammation in a number of chronic illnesses and mental disorders; however, studies on sleep quality are scarce. The aim of this study was to test the association between the inflammatory potential of the diet and sleep quality in a cohort of Italian adults. Methods: A cross-sectional analysis of baseline data of the Mediterranean healthy Eating, Aging, and Lifestyle (MEAL) study was conducted on 1936 individuals recruited in the urban area of Catania during 2014-2015 through random sampling. A food frequency questionnaire and other validated instruments were used to calculate …

Dietary Intervention With Black Raspberries To Reduce Colitis Symptoms In Mice Fed Either Standard Ain93g Diet Or The Total Western Diet (P05-021-19), Daphne Michelle Rodriguez Jimenez, Michaela Brubaker, Elizabeth Park, Canyon Neal, Korry Hintze, Abby D. Benninghoff

Chemistry and Biochemistry Faculty Publications

Approximately 1.4 million people suffer from inflammatory bowel disease, which is a major risk factor for developing colitis associated colorectal cancer (CAC). Dietary interventions with the goal to reduce colon inflammation and encourage gut microbiome homeostasis may be a strategy to reduce the risk of CAC. The antioxidants and anti-inflammatory compounds present in black raspberries (BRB) have demonstrated protective effects in the colon epithelium and may alter the composition of the gut microbiome. Previously, we showed that dietary supplementation with black raspberries significantly suppressed colitis and colon tumorigenesis promoted by the consumption of a Western type diet in mice. The …

Unexplored Diversity Of The Mesophotic Echinoderm Fauna Of The Easter Island Ecoregion, Ariadna Mecho, Erin E. Easton, Javier Sellanes, Matthias Gorny, Christopher Mah

School of Earth, Environmental, & Marine Sciences Faculty Publications

The Easter Island ecoregion (EIE) is one of the most remote marine areas of the world and encompasses a vast and fragile ecosystem including oceanic islands and seamounts. In January 2014 and March 2016, a remotely operated vehicle was used to explore a subsurface peak off Easter Island (27.23°S, 109.48°W) and a seamount (26.92°S, 110.26°W), respectively located 10 km southwest and 98 km west of the island. More than 950 echinoderms were observed in the 5 h of video recorded during the seven dives conducted at depths between ~ 160 and 280 m. The communities of echinoderms observed at these …

Engaged Communication Scholarship For Environmental Justice: A Research Agenda, Chad Raphael

Communication

As a discipline of crisis and care, environmental communication needs to address questions of environmental justice. This article argues that the most appropriate approach to studying environmental justice communication is engaged scholarship, in which academics collaborate with community partners, advocates, and others to conduct research. The article reviews prior engaged communication scholarship on environmental justice, and proposes four streams of future research, focused on news and information, deliberation and participation, campaigns and movements, and education and literacy.

Maximizing And Modeling Malonyl-Coa Production In Escherichia Coli, Tatiana Thompson Silveira Mello

LSU Master's Theses

In E. coli, fatty acid synthesis is catalyzed by the enzyme acetyl-CoA carboxylase (ACC), which converts acetyl-CoA into malonyl-CoA. Malonyl-CoA is a major building block for numerous of bioproducts. Multiple parameters regulate the homeostatic cellular concentration of malonyl-CoA, keeping it at a very low level. Understanding how these parameters affect the bacterial production of malonyl-CoA is fundamental to maximizing it and its bioproducts. To this end, competing pathways consuming malonyl-CoA can be eliminated, and optimal nutritional and environmental conditions can be provided to the fermentation broth. Most previous studies utilized genetic modifications, expensive consumables, and high-cost quantification methods, making …

Reproductive Parameters And Methodologies For The Culture Of Golden Topminnows (Fundulus Chrysotus) And Bluenose Shiners (Pteronotropis Welaka), Jacob A. Fetterman

LSU Master's Theses

The global ornamental fish trade has expanded over the past 20 years, requiring captive rearing methods to be improved or developed for species of interest. Aquaculture of desirable species is preferable over wild harvest to conserve natural habitats and biodiversity. This thesis focused on improving culture methods for Golden Topminnows Fundulus chrysotus and developing culture methods for Bluenose Shiners Pteronotropis welaka, both native fishes of the southeastern United States with ornamental demand. A combination of reproductive metric analyses, examination of historical collections, and captive spawning trials were employed to target specific objectives for each species. In female Golden Topminnows, …

Epidemiologic Evaluation Of Nhanes For Environmental Factors And Periodontal Disease, P. Emecen-Huja, H. -F. Li, J. L. Ebersole, J. Lambert, Heather M. Bush

Biostatistics Faculty Publications

Periodontitis is a chronic inflammation that destroys periodontal tissues caused by the accumulation of bacterial biofilms that can be affected by environmental factors. This report describes an association study to evaluate the relationship of environmental factors to the expression of periodontitis using the National Health and Nutrition Examination Study (NHANES) from 1999–2004. A wide range of environmental variables (156) were assessed in patients categorized for periodontitis (n = 8884). Multiple statistical approaches were used to explore this dataset and identify environmental variable patterns that enhanced or lowered the prevalence of periodontitis. Our findings indicate an array of environmental variables were …

An Interdisciplinary Weight Loss Program Improves Body Composition And Metabolic Profile In Adolescents With Obesity: Associations With The Dietary Inflammatory Index, Yasmin Alaby Martins Ferreira, Ana Claudia Pelissari Kravchychyn, Sofia De Castro Ferreira Vicente, Raquel Munhoz Da Silveira Campos, Lian Tock, Lila Missae Oyama, Valter Tadeu Boldarine, Deborah Cristina Landi Masquio, David Thivel, Nitin Shivappa, James R. Hébert, Ana R. Dâmaso

Faculty Publications

Background and Aims: The prevalence of overweight and obesity consitutes a global epidemic and it is growing around the world. Food and nutrition are essential requirements for promoting health and protecting against non-communicable chronic diseases, such as obesity and cardiovascular disease. Specific dietary components may modulate inflammation and oxidative stress in obese individuals. The Dietary Inflammatory Index (DII®) was developed to characterize the anti- and pro-inflammatory effects of individuals' diet. Few studies have investigated the role of diet-associated inflammation in adolescents with obesity. The present study aims to investigate the effects of an interdisciplinary weight loss therapy on DII scores …

The Slow Displacement Of Smallholder Farming Families: Land, Hunger, And Labor Migration In Nicaragua And Guatemala, Lindsey Carte, Birgit Schmook, Claudia Radel, Richard Johnson

Environment and Society Faculty Publications

Smallholders worldwide continue to experience processes of displacement from their lands under neoliberal political-economic governance. This displacement is often experienced as “slow”, driven by decades of agricultural policies and land governance regimes that favor input-intensive agricultural and natural resource extraction and export projects at the expense of traditional agrarian practices, markets, and producers. Smallholders struggle to remain viable in the face of these forces, yet they often experience hunger. To persist on the land, often on small parcels, families supplement and finance farm production with family members engaging in labor migration, a form of displacement. Outcomes, however, are uneven and …

Frost Identification Guide For Canola And Pulses, Ben Biddulph, Department Of Primary Industries And Regional Development, Western Australia

Bulletins 4000 -

Frost damage reduces crop yield and grain quality. Early identification of symptoms allows timely crop salvage decisions to be made.

”Cyberworld” As A Theme For A University-Wide First-Year Common Course, Kristen Przyborski, Frank Breitinger, Lauren Beck, Ronald S. Harichandran

Engineering and Applied Science Education Faculty Publications

Nowadays we all live in a cyber world and use the internet for emailing, banking, streaming video, shopping, reading news, or other activities. Given all the time people spend online, it is important that all students (regardless of their major) learn some basics about living in a cyber world, e.g., strategies for online safety, impact of artificial intelligence, digital forensics or ancestry.com. To facilitate students from many majors to learn about important issues related to the internet, eight faculty from a variety of disciplines at the University of New Haven integrated the theme of Cyber World into our team-taught, first-year …

Mixed Dish Recognition Through Multi-Label Learning, Yunan Wang, Jing-Jing Chen, Chong-Wah Ngo, Tat-Seng Chua, Wanli Zuo, Zhaoyan Ming

Research Collection School Of Computing and Information Systems

Mix dish recognition, whose goal is to identify each of the dish type presented on one plate, is generally regarded as a difficult problem. The major challenge of this problem is that different dishes presented in one plate may overlap with each other and there may be no clear boundaries among them. Therefore, labeling the bounding box of each dish type is difficult and not necessarily leading to good results. This paper studies the problem from the perspective of multi-label learning. Specially, we propose to perform dish recognition on region level with multiple granularities. For experimental purpose, we collect two …