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Final Silver Bow Creek Conservation Area (Sbcca) Construction Quality Assurance Plan (Cqap), Pioneer Technical Services, Inc. Apr 2026

Final Silver Bow Creek Conservation Area (Sbcca) Construction Quality Assurance Plan (Cqap), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


The Compass - Volume 95 Issue 1 - Complete Issue, Scott R. Beason Apr 2026

The Compass - Volume 95 Issue 1 - Complete Issue, Scott R. Beason

The Compass: Earth Science Journal of Sigma Gamma Epsilon

No abstract provided.


Developing Blockchain-Based Transparent E-Commerce Solutions For Danish Smes To Promote Sustainable Design Products, Somnath Mazumdar, Robert John Kauffman, Thomas Jensen, Raghava Rao Mukkamala, Jan Damsgaard Apr 2026

Developing Blockchain-Based Transparent E-Commerce Solutions For Danish Smes To Promote Sustainable Design Products, Somnath Mazumdar, Robert John Kauffman, Thomas Jensen, Raghava Rao Mukkamala, Jan Damsgaard

Research Collection School Of Computing and Information Systems

Typically, a firm's objectives include establishing consumer confidence, preserving its brand image, and developing a profitable business strategy. Consumers now place greater emphasis on the sustainability and transparency of their purchases. Given environmental and economic limitations, firms are often compelled to implement sustainable production methods. This is especially a struggle for small- and medium-sized enterprises (SMEs) with new technology, as it can increase their risk of failure. This has led to a problem for consumers, who must cross-check the sustainability-related claims of the firms they buy from. This is challenging because of limited process trace data and restricted enforcement capabilities. …


Teamwise: Exploring Virtually Embodied Ai Facilitation For Video-Based Team Onboarding, Venkata Akhila Rani Obilisetty, Mikkeline Elleby, Anthony Tang, April Yi Wang Apr 2026

Teamwise: Exploring Virtually Embodied Ai Facilitation For Video-Based Team Onboarding, Venkata Akhila Rani Obilisetty, Mikkeline Elleby, Anthony Tang, April Yi Wang

Research Collection School Of Computing and Information Systems

AI-mediated facilitation has emerged as a scalable approach to supporting onboarding and coordination in newly formed remote teams, yet existing systems are predominantly text-based. To explore how video-based, virtually embodied AI facilitators shape team experiences, we present TeamWise, which joins video-based onboarding meetings as an on-screen avatar. TeamWise guides teams through a structured facilitation flow of low-stakes activities to foster rapport, mutual awareness, and shared identity. While the overall sequence of activities and facilitation goals is predefined, the facilitator’s turn-by-turn utterances are generated dynamically by an LLM in response to participant input. We conducted a formative study of TeamWise to …


Reasoning On Time-Series For Financial Technical Analysis, Kelvin J. L. Koa, Jan Chen, Yunshan Ma, Huanhuan Zheng, Tat-Seng Chua Apr 2026

Reasoning On Time-Series For Financial Technical Analysis, Kelvin J. L. Koa, Jan Chen, Yunshan Ma, Huanhuan Zheng, Tat-Seng Chua

Research Collection School Of Computing and Information Systems

While Large Language Models have been used to produce interpretable stock forecasts, they mainly focus on analyzing textual reports but not historical price data, also known as Technical Analysis. This task is challenging as it switches between domains: the stock price inputs and outputs lie in the time-series domain, while the reasoning step should be in natural language. In this work, we introduce Verbal Technical Analysis (VTA), a novel framework that combine verbal and latent reasoning to produce stock time-series forecasts that are both accurate and interpretable. To reason over time-series, we convert stock price data into textual annotations and …


Who Said Cve? How Vulnerability Identifiers Are Mentioned By Humans, Bots, And Agents In Pull Requests, Pien Rooijendijk, Christoph Treude, Mairieli Wessel Apr 2026

Who Said Cve? How Vulnerability Identifiers Are Mentioned By Humans, Bots, And Agents In Pull Requests, Pien Rooijendijk, Christoph Treude, Mairieli Wessel

Research Collection School Of Computing and Information Systems

Vulnerability identifiers such as CVE, CWE, and GHSA are standardised references to known software security issues, yet their use in practice is not well understood. This paper compares vulnerability ID use in GitHub pull requests authored by autonomous agents, bots, and human developers. Using the AIDev pop dataset and an augmented set of pull requests from the same repositories, we analyse who mentions vulnerability identifiers and where they appear. Bots account for around 69.1% of all mentions, usually adding few identifiers in pull request descriptions, while human and agent mentions are rarer but span more locations. Qualitative analysis shows that …


Downstream Effects Of Post Aerobic Digestion And Divalent Cation Treatment: Dewaterability, Phosphorus Mitigation, And Process Odors, Maya Marisol Quijano Garcia Apr 2026

Downstream Effects Of Post Aerobic Digestion And Divalent Cation Treatment: Dewaterability, Phosphorus Mitigation, And Process Odors, Maya Marisol Quijano Garcia

Civil & Environmental Engineering Theses & Dissertations

This study evaluated post-aerobic digestion (PAD) with aeration, mixing, and divalent cation addition to improve phosphorus capture, dewaterability, and odor control in thermal hydrolysis process (THP)–treated anaerobic digestate at the Hampton Roads Sanitation District’s Atlantic Treatment Plant. A three-day PAD process was operated under constant air flow (5 LPM) and dissolved oxygen (DO)-setpoint (0.2 mg/L) aeration conditions with Ca(OH)₂ or Mg(OH)₂ dosing. Aeration and mixing alone increased polymer demand by 14–46 % relative to untreated influent, indicating enhanced extracellular polymeric substance release. Chemical conditioning partially mitigated this increase but did not restore polymer demand to baseline levels. Dewatered cake total …


Biocrude From Organic Waste And Its Conversion To Hard Carbon: Experimental And Modeling Study, Isamu Umeda Apr 2026

Biocrude From Organic Waste And Its Conversion To Hard Carbon: Experimental And Modeling Study, Isamu Umeda

Civil & Environmental Engineering Theses & Dissertations

This study establishes a technical and theoretical foundation for the efficient conversion of organic waste into biocrude and high-value carbon materials, aiming to facilitate the industrialization of hydrothermal and solvothermal liquefaction. The dissertation research is structured as follows:

Chapter 2 developed a novel chemical kinetic model for the HTL of corn stover based on elemental balances (C, H, N, and O). By incorporating temperature, residence time, solid loading as an independent variable, the model successfully predicted product yields and properties, revealing that there was non-pseudo-first-order reaction pathways in the conversion of water soluble organics in aqueous phase (AP) to hydrochar. …


Personality Predictors Of Cybersecurity Vulnerability: Insights From Self-Reports And Stimulated Threat Scenarios, Saroja Roy Grandhi Apr 2026

Personality Predictors Of Cybersecurity Vulnerability: Insights From Self-Reports And Stimulated Threat Scenarios, Saroja Roy Grandhi

Psychology Theses & Dissertations

In this cyber dependent and enabled era, understanding the role of human factors in digital security is essential. This study investigates the relationship between Big-Five personality traits and cybersecurity behaviors by examining both self-reported and stimulated behaviors in security threat scenarios. Participants completed validated questionnaires to report their personality traits, cybersecurity practices and engage in task-based stimulations to capture behaviors such as phishing detection, password creation, and response to security alerts. The study tested whether higher conscientiousness, openness, and agreeableness would be associated with stronger cybersecurity practices and smaller discrepancies between self-reported and observed behaviors. And, whether greater extraversion and …


Dendrimer Nanogels With Built-In Free Radical Scavenging Enable Efficient Topical Delivery Of A Hydrophilic Antioxidant To Restore Lens Redox Balance For Cataract Treatment, Lin Qi, Huari Kou, Anna Chernatynskaya, Da Huang, Vimalin Jeyalatha Mani, Humeyra Karacal, Nuran Ercal, Hu Yang Apr 2026

Dendrimer Nanogels With Built-In Free Radical Scavenging Enable Efficient Topical Delivery Of A Hydrophilic Antioxidant To Restore Lens Redox Balance For Cataract Treatment, Lin Qi, Huari Kou, Anna Chernatynskaya, Da Huang, Vimalin Jeyalatha Mani, Humeyra Karacal, Nuran Ercal, Hu Yang

Chemistry Faculty Research & Creative Works

Cataract is a leading cause of vision impairment worldwide and are primarily caused by oxidative stress that damages and aggregates lens proteins, leading to lens opacification. However, the eye's anatomical barriers limit the penetration and bioavailability of antioxidant therapies. To address this challenge, a dendrimer-based nanogel with a built-in reactive oxygen species (ROS)-scavenging capability developed by us was employed to deliver the antioxidant N-acetylcysteine (NAC) to the lens. NAC was loaded into a generation-5 PEGylated poly(amidoamine) dendrimer (G5-PEG-TK, termed the GPT) nanogel. The resulting NAC-GPT was characterized for its ROS-scavenging activity, bioavailability, and corneal permeability. The efficacy of NAC-GPT was …


Synthesis Of Piperidine Heterocycles With Specific Functional Groups Via Sn2 Reactions, Teyanna Monroe Apr 2026

Synthesis Of Piperidine Heterocycles With Specific Functional Groups Via Sn2 Reactions, Teyanna Monroe

Honors Theses

Piperidine is a heavily utilized nitrogen containing heterocycle found in numerous pharmaceutical agents, solidifying its importance as a building block in drug development. The focus of this research is to investigate different mechanisms of action for adding and replacing various functional groups utilizing readily available lab materials. These findings would lead to determining the overall influence of substitution patterns and functional groups have on stereochemistry, reactivity, and overall conformation of the piperidine ring. The synthetic approach involves the formation of 3-bromo-5-methoxy-tosylpiperidine intermediate through acid promoted cyclization, followed by nucleophilic substitution reactions to introduce various functional groups. Reaction progress and product …


Rethinking News Classification Through A Multi-Dimensional Framework, Luana De Jesus Ferreira Apr 2026

Rethinking News Classification Through A Multi-Dimensional Framework, Luana De Jesus Ferreira

Honors Theses

This thesis proposes a multi-dimensional framework for news classification that evaluates articles across three independent dimensions: headline accuracy, language neutrality, and content reliability. These dimensions produce both a continuous reliability score and a five-tier interpretive scale, while additionally classifying articles by genre and topic. To operationalize this framework, a structured annotation protocol was developed and applied to a dataset of 373 news articles drawn from 79 outlets spanning a wide range of contemporary media ecosystem. A binary Logistic Regression classifier trained on the ISOT Fake News Dataset was then evaluated against this dataset to examine how a model trained on …


A Real Account Of Deep Fakes, Benjamin L.W Sobel Apr 2026

A Real Account Of Deep Fakes, Benjamin L.W Sobel

Michigan Law Review

Laws regulating pornographic deepfakes are written to prohibit “digital forgeries,” “false” images, or media “indistinguishable” from “authentic” recordings. Yet the typical anti-deepfake law covers materials that aren’t forgeries, aren’t false, and that reasonable observers can easily distinguish from authentic recordings. Though drafted as if they regulate statements of fact, anti-deepfake laws actually target certain outrageous depictions per se—and rightly so, because pornographic deepfakes cause harm irrespective of their truth or falsity. However, the inapposite language of facts results in statutes with crucial ambiguities. Moreover, because anti-deepfake laws ban outrageous depictions irrespective of the factual assertions they make, they differ fundamentally …


Observational Diagnostics And Spectroscopic Detection Of Tropospheric Trace Gases And Oxidation Processes, Callum E. Flowerday Mar 2026

Observational Diagnostics And Spectroscopic Detection Of Tropospheric Trace Gases And Oxidation Processes, Callum E. Flowerday

Theses and Dissertations

The troposphere is governed by photochemical and radical-mediated processes that control atmospheric oxidation capacity, secondary pollutant formation, and the chemical lifetime of gases. Quantitative understanding of these processes requires both robust observational frameworks capable of resolving complex precursor–product relationships and instrumentation with sufficient sensitivity and selectivity to detect reactive and low-concentration species. This dissertation advances atmospheric chemistry through the parallel development of quantitative observational methodologies and refined spectroscopic measurement techniques. The first component of this work evaluates atmospheric oxidation systems using long-term monitoring data and empirical diagnostics. Multi-year analyses of ozone and particulate matter trends were conducted to characterize variability …


Employing Effective Solution Methods For Caputo-Based Sequential Fractional Models, Eman A. A. Ziada, Mohamed F. Abouelenein, Hijaz Ahmad, Monica Botros Mar 2026

Employing Effective Solution Methods For Caputo-Based Sequential Fractional Models, Eman A. A. Ziada, Mohamed F. Abouelenein, Hijaz Ahmad, Monica Botros

Mathematical Modelling and Numerical Simulation with Applications

This paper investigates a class of nonlinear sequential singular fractional differential equations (FDEs) involving Caputo derivatives. This type of equation has several key advantages that enhance its value, such as capturing memory and hereditary effects. Viscoelastic materials and anomalous diffusion, as well as biological systems, can take advantage of this feature. In addition, fractional derivatives possess a sequential structure that enables the implementation of multiscale processes and hierarchical memory responses. Moreover, it provides an effective and flexible framework for solving differential equations compared to classical differential equations. It can therefore be used to model complex systems in physics, biology, and …


Optimal Control Strategies For Infectious Diseases: A Numerical Simulation Approach, M. Abu Salek, Jannatun Nayeem, Romana Yesmin, M. Haider Ali Biswas, M. Humayun Kabir Mar 2026

Optimal Control Strategies For Infectious Diseases: A Numerical Simulation Approach, M. Abu Salek, Jannatun Nayeem, Romana Yesmin, M. Haider Ali Biswas, M. Humayun Kabir

Mathematical Modelling and Numerical Simulation with Applications

Various infectious diseases, such as Tuberculosis and Hepatitis B virus (HBV), caused by Mycobacterium bacteria and hepatitis B virus, respectively, pose serious threats worldwide. This paper examines the spread of these diseases using a mathematical model that incorporates control measures, including vaccination and awareness programs. We use a system of differential equations with control variables and apply Pontryagin's principle to determine optimal control strategies. The stability of the Disease Free Equilibrium (DFE) has been analysed and demonstrated to be both locally and globally asymptotically stable when the basic reproduction number remains below unity, thereby ensuring disease elimination. Furthermore, the Endemic …


Exact Soliton Solutions Of The Nonlinear Time-Fractional Schrödinger Equation Via Atangana–Baleanu And M-Truncated Operators, Bahadır Kopçasiz, Fatma Nur Kaya Sağlam, Mehmet Şenol Mar 2026

Exact Soliton Solutions Of The Nonlinear Time-Fractional Schrödinger Equation Via Atangana–Baleanu And M-Truncated Operators, Bahadır Kopçasiz, Fatma Nur Kaya Sağlam, Mehmet Şenol

Mathematical Modelling and Numerical Simulation with Applications

The main objective of this work is to obtain exact soliton solutions for a nonlinear time-fractional equation model describing wave profiles arising in various physical systems. To derive different wave structures associated with the considered model, two analytical techniques are employed: the extended G'\G^2-expansion method and the modified auxiliary equation (MAE) approach. A wave transformation is applied to reduce the nonlinear time-fractional equation to a nonlinear ordinary differential equation (NLODE) by means of the M-truncated and Atangana-Baleanu (AB) fractional operators. Several classes of solutions, including exponential, hyperbolic, and trigonometric wave forms, are obtained. Over and above the analytical results, graphical …


Toxicity, Chemistry, And Public Health Relevance Of Emerging Nicotine Analog Vapes, Pods, And Pouches., Rhea Raghu, Mohana Sengupta, Karen Lin, Felix Effah, Robert M. Strongin, Irfan Rahman Mar 2026

Toxicity, Chemistry, And Public Health Relevance Of Emerging Nicotine Analog Vapes, Pods, And Pouches., Rhea Raghu, Mohana Sengupta, Karen Lin, Felix Effah, Robert M. Strongin, Irfan Rahman

Chemistry Faculty Publications and Presentations

Electronic nicotine delivery system manufacturers, such as Charlie's Holdings Inc., ECBlend, Outlaw, and NicRiver, have recently introduced nicotine analogs, such as 6-methyl nicotine, 6-MN ("Metatine"), and nicotinamide, NA ("Nixamide," "Nixodine," or "Nixotin-free base and salt") in products to circumvent the U.S. FDA's premarket tobacco product application (PMTA) requirements. Marketed as "tobacco-free," "PMTA-exempt," or "FDA-approved," these compounds now appear in oral nicotine pouches and disposable bars/vapes from brands such as Outlaw Dip, Kumi-Six, SBX, Katchmi, and Spree Bar under proprietary labels including "NoNic6," "Metatine," or "NIC-SAFE." These products often mimic the appeal of conventional nicotine delivery systems, with extensive use of …


A Systematic Review Of Mathematical Interpretations Of The Weton Marriage Tradition Within Islamic Cultural Contexts, Ratna Damayanti, Surya Sari Faradiba Mar 2026

A Systematic Review Of Mathematical Interpretations Of The Weton Marriage Tradition Within Islamic Cultural Contexts, Ratna Damayanti, Surya Sari Faradiba

Jurnal Pendidikan Sains

This study is grounded in the limited integration of mathematics, culture, and religion within academic discussions of local traditions, particularly the weton marriage calculation practice. It aims to explore the mathematical concepts embedded in weton calculations and to analyse these practices from an Islamic law perspective within an interdisciplinary framework. The study employs a Systematic Literature Review (SLR) method following the six-stage PRISMA 2020 protocol, including the formulation of research questions, development of a search strategy, application of inclusion and exclusion criteria, study selection, quality assessment, and thematic synthesis. Data were collected from Google Scholar and Garuda using the keywords …


Design And In Silico Modeling Of Heterocyclic-Based Xanthone Derivatives As Potential Anticancer Agents Through Tyrosine Kinase Inhibition, Yehezkiel Steven Kurniawan, Ervan Yudha, Nela Fatmasari, Radite Yogaswara, Harno Dwi Pranowo, Eti Nurwening Sholikhah, Jumina Jumina Mar 2026

Design And In Silico Modeling Of Heterocyclic-Based Xanthone Derivatives As Potential Anticancer Agents Through Tyrosine Kinase Inhibition, Yehezkiel Steven Kurniawan, Ervan Yudha, Nela Fatmasari, Radite Yogaswara, Harno Dwi Pranowo, Eti Nurwening Sholikhah, Jumina Jumina

Makara Journal of Science

Cancer is one of the deadliest diseases nowadays, and tyrosine kinase receptors play crucial roles in cancer cell survival, differentiation, proliferation, and migration. This study designed and developed a new inhibitor from heterocyclic-based xanthone derivatives to target two tyrosine kinase receptors, epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR), through in silico screening. Eighteen heterocyclic-based xanthones were evaluated through molecular docking for both receptors. All heterocyclic-based xanthones gave the root mean square deviation (RMSD) value lower than 2.00 Å. Xanthone with isobenzothiazole substituent (iBzThio) was found as the most potent inhibitor with binding energies of -10.60 and …


Anthrone-Based Dummy Molecularly Imprinted Polymer For The Selective Detection Of Fluorene And Phenanthrene In Simulated River Water, Aria Pinandita, Nurrahmi Handayani, Muhammad Iqbal, Untung Triadhi, Rusnadi Rusnadi, Samitha Dewi Djajanti, Muhammad Bachri Amran, Muhammad Ali Zulfikar Mar 2026

Anthrone-Based Dummy Molecularly Imprinted Polymer For The Selective Detection Of Fluorene And Phenanthrene In Simulated River Water, Aria Pinandita, Nurrahmi Handayani, Muhammad Iqbal, Untung Triadhi, Rusnadi Rusnadi, Samitha Dewi Djajanti, Muhammad Bachri Amran, Muhammad Ali Zulfikar

Makara Journal of Science

A dummy-template molecularly imprinted polymer (DMIP) was synthesized via precipitation polymerization using anthrone as a template analog for the selective analysis of low-molecular-weight polycyclic aromatic hydrocarbons (PAHs), specifically fluorene and phenanthrene. Styrene, benzoyl peroxide, and ethylene glycol dimethacrylate were employed as the functional monomer, radical initiator, and crosslinking agent, respectively. The synthesized polymers were characterized by Fourier-transform infrared spectroscopy, scanning electron microscopy, and particle size analysis. The imprinting factors were 1.16 and 1.09 for fluorene and phenanthrene, respectively, indicating enhanced affinity of the imprinted sites. High-performance liquid chromatography analysis following DMIP-based solid-phase extraction yielded recoveries of 91.49% ± 3.87% for …


Axial Sulfur-Coordination Engineering Boosting Fe–N–C Catalysts For High-Performance Proton Exchange Membrane Fuel Cells, Lin Lin, Xiu-Xuan Hou, Zhe-Chen Fan, Yi-Xuan Yin, Wei-Yi Zhao, Kai Wei, Yu-Die Zhou, Li-Na Hou, Ying Wang, Hao Wan, Jun-Jie Ge Mar 2026

Axial Sulfur-Coordination Engineering Boosting Fe–N–C Catalysts For High-Performance Proton Exchange Membrane Fuel Cells, Lin Lin, Xiu-Xuan Hou, Zhe-Chen Fan, Yi-Xuan Yin, Wei-Yi Zhao, Kai Wei, Yu-Die Zhou, Li-Na Hou, Ying Wang, Hao Wan, Jun-Jie Ge

Journal of Electrochemistry

Fe-N-C catalysts have long suffered from kinetically sluggish oxygen reduction reaction (ORR) due to excessive adsorption strength toward oxygen intermediates and low site utilization. Heteroatom doping effectively accelerates ORR reaction kinetics through electronic structure modulation of metal sites for optimal intermediate adsorption, while chemical vapor deposition (CVD) enhances the turnover frequency (TOF) of active sites. Herein, we developed an FeSNC catalyst featuring abundant FeS1N4 sites via a dual-precursor CVD strategy. Experimental and theoretical analyses revealed that S incorporation disrupts the symmetric coordination of active sites, which optimizes OH* adsorption energies from 0.212 eV to 1.194 eV. Moreover, …


Association Between The Dietary Index For Gut Microbiota (Di-Gm) And Colorectal Cancer In The Plco Cohort, Bezawit E. Kase, Angela D. Liese Ph.D., Jiajia Zhang Ph.D., Elizabeth Angela Murphy, Susan E. Steck Phd, Mph, Rd Mar 2026

Association Between The Dietary Index For Gut Microbiota (Di-Gm) And Colorectal Cancer In The Plco Cohort, Bezawit E. Kase, Angela D. Liese Ph.D., Jiajia Zhang Ph.D., Elizabeth Angela Murphy, Susan E. Steck Phd, Mph, Rd

Faculty Publications

Objectives: The study aimed to examine the association between a dietary index for gut microbiota (DI-GM) and the risk of incident colorectal cancer (CRC). Clarifying the role of diet-induced alterations in the composition and function of gut microbiota on the development of CRC can contribute to prevention efforts. Methods: Participants from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening trial enrolled in the intervention arm and who completed baseline assessments were included in the analysis (n = 55,685). The DI-GM is a literature-derived index used to score diet quality in terms of maintaining healthy gut microbiota. A time-dependent Cox model …


Association Between The Dietary Index For Gut Microbiota (Di-Gm) And Colorectal Cancer In The Plco Cohort, Bezawit E. Kase, Angela D. Liese, Jiajia Zhang, Elizabeth Angela Murphy, Susan E. Steck Mar 2026

Association Between The Dietary Index For Gut Microbiota (Di-Gm) And Colorectal Cancer In The Plco Cohort, Bezawit E. Kase, Angela D. Liese, Jiajia Zhang, Elizabeth Angela Murphy, Susan E. Steck

Faculty Publications

Objectives: The study aimed to examine the association between a dietary index for gut microbiota (DI-GM) and the risk of incident colorectal cancer (CRC). Clarifying the role of diet-induced alterations in the composition and function of gut microbiota on the development of CRC can contribute to prevention efforts. Methods: Participants from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening trial enrolled in the intervention arm and who completed baseline assessments were included in the analysis (n = 55,685). The DI-GM is a literature-derived index used to score diet quality in terms of maintaining healthy gut microbiota. A time-dependent Cox model …


Design, Synthesis, And Bioevaluation Of Moxifloxacin Hydrazide Metal Complexes: Integrated Spectroscopic, Computational, Antimicrobial, And Anticancer Investigations, Abbas Mamdoh Abbas, Sara Reda Fisal, Ibrahim A.I. Ali, W. Christropher Boyd, Haitham F. Kalil, Adel Sayed Orabi Mar 2026

Design, Synthesis, And Bioevaluation Of Moxifloxacin Hydrazide Metal Complexes: Integrated Spectroscopic, Computational, Antimicrobial, And Anticancer Investigations, Abbas Mamdoh Abbas, Sara Reda Fisal, Ibrahim A.I. Ali, W. Christropher Boyd, Haitham F. Kalil, Adel Sayed Orabi

Chemistry Faculty Publications

This study reports the synthesis, spectroscopic characterization, and biological evaluation of a novel moxifloxacin hydrazide derivative (MOX-H) and its metal complexes with Co(II), Ni(II), Cu(II), VO(IV), and Gd(III). The ligand was synthesized by hydrazinolysis of moxifloxacin hydrochloride, and the resulting hydrazide was subsequently complexed with the respective metal salts. The interaction between MOX-H and the metal ions yielded the corresponding complexes, formulated as [Co(H2O)Cl(MOX-H)2]Cl & centerdot;2.5H2O, [Ni(H2O)Cl(MOX-H)2]Cl.4.5H2O, [VO(MOX-H)2]SO4.3.5H2O, [Gd (H2O)(MOX-H)2(NO3)2]NO3.2H2O, and [Cu(MOX-H)2(H2O)Cl]Cl & centerdot;xH2O (where x = 2, 2.5, 0.5, for products synthesized via template, microwave-assisted, and hydrothermal methods, respectively). The synthesized analogues were characterized by elemental analysis (CHN), FT-IR, …


Objective Conditioning Via Latent-Factor Modeling, Kalman-Smoothing, And Hidden Markov Clustering: An Application To Empirical Asset Pricing, Melanie R. Neller Mar 2026

Objective Conditioning Via Latent-Factor Modeling, Kalman-Smoothing, And Hidden Markov Clustering: An Application To Empirical Asset Pricing, Melanie R. Neller

Theses and Dissertations

Empirical asset pricing relies heavily on conditioning sets--industry groupings, size buckets, valuation screens, and other researcher-defined partitions--to structure cross-sectional tests and portfolio construction. While intuitive, such partitions risk blending heterogeneous firms, masking latent exposures, and introducing omitted-variable bias. This thesis develops an objective, mathematically grounded conditioning pipeline that replaces subjective groupings with latent-factor extraction, Kalman-based data techniques, and probabilistic clustering via Gaussian hidden Markov models (HMMs). Using CRSP monthly returns, the framework stabilizes noisy return data, extracts systematic structure through principal component analysis (PCA), identifies homogeneous stock cohorts through HMM clustering, and models regime persistence using Markov transition matrices. These …


Advances In Research On Mechanisms And Prevention And Control Technologies For Solid-Phase Production In Hydraulically Fractured Coalbed Methane Wells, Zhang Fengsan, Wu Jinqiao, Lin Jin, Li Yu, Zhang Ying, Li Bing, Zhang Guobiao, Sun Ying, Gan Yuke Mar 2026

Advances In Research On Mechanisms And Prevention And Control Technologies For Solid-Phase Production In Hydraulically Fractured Coalbed Methane Wells, Zhang Fengsan, Wu Jinqiao, Lin Jin, Li Yu, Zhang Ying, Li Bing, Zhang Guobiao, Sun Ying, Gan Yuke

Coal Geology & Exploration

Background The effective coalbed methane (CBM) exploitation using hydraulic fracturing wells is severely constrained by two major solid-phase production issues: coal fines blockage and proppant flowback. The mechanisms behind both issues are associated with complex interplays between geological conditions and engineering disturbances. This study presents a systematic review of the current status of domestic and international research on the mechanisms of the solid-phase production, as well as relevant prevention and control methods. Furthermore, future research directions are proposed.Advances The solid-phase production in hydraulically fractured CBM wells essentially arises from flow-solid-chemical multi-field coupling processes under interplays between geological conditions and …


Positive And Negative Pressure Distributions And Gas Migration Mechanisms Under Gas Drainage From Coal Seams Using Ultra-Long Directional Boreholes, Li Quanxin, Zhao Yuechen, Mou Quanbin, Wang Liang, Fang Jun, Wang Chenghao Mar 2026

Positive And Negative Pressure Distributions And Gas Migration Mechanisms Under Gas Drainage From Coal Seams Using Ultra-Long Directional Boreholes, Li Quanxin, Zhao Yuechen, Mou Quanbin, Wang Liang, Fang Jun, Wang Chenghao

Coal Geology & Exploration

Background Gas drainage via ultra-long directional boreholes plays a significant role in gas control in coal mines. To ensure safe and efficient gas drainage using these boreholes, it is critical to determine the mechanisms behind positive- negative pressure coupling, as well as the dominant mechanisms governing gas migration. However, the evolutionary patterns of positive-negative pressure zoning within the boreholes and the primary factors influencing gas drainage efficiency have yet to be accurately characterized. Methods Under the engineering background of the Shendong Baode Coal Mine, this study developed a multi-field coupling model integrating diffusion, seepage, and in-borehole flow fields based on …


Mechanisms Behind The Controlling Effects Of Temperature-Pressure Conditions On The Dynamic Ch4–H2O Production From Bituminous Coal, Zhang Hewei, Shen Jian, Li Kexin, Wu Caifang Mar 2026

Mechanisms Behind The Controlling Effects Of Temperature-Pressure Conditions On The Dynamic Ch4–H2O Production From Bituminous Coal, Zhang Hewei, Shen Jian, Li Kexin, Wu Caifang

Coal Geology & Exploration

Background For deep coalbed methane (CBM) exploitation, the temperature-pressure synergistic effect in the CH4-H2O two-phase flow remains poorly understood, restricting the establishment of efficient CBM production systems.Methods This study investigated the No.13 coal seam in the Guanjiaya Coal Mine along the eastern margin of the Ordos Basin. Using low-field nuclear magnetic resonance (LF-NMR) and nuclear magnetic resonance imaging (NMRI) techniques, this study explored the dynamic process of CH4 displacing water and associated gas-water production mechanisms under different displacement pressures (2‒8 MPa) and temperatures (25 ℃ and 60 ℃).Results and Conclusions The sample used …


Mechanisms Behind The Control Of Floor Failure In Deep Coal Mines By Hydraulic Fracturing Based On Power-Law Fracture Networks, Duan Hongfei, Ye Dayu, Zhao Lijuan, Zeng Yifan, Zou Junpeng, Yu Guofeng, Meng Xiang Mar 2026

Mechanisms Behind The Control Of Floor Failure In Deep Coal Mines By Hydraulic Fracturing Based On Power-Law Fracture Networks, Duan Hongfei, Ye Dayu, Zhao Lijuan, Zeng Yifan, Zou Junpeng, Yu Guofeng, Meng Xiang

Coal Geology & Exploration

Objective Hydraulic fracturing of coal seam floors represents an important technical approach to mitigating damage to the floor rock masses through proactive pressure relief and to improving seepage pathways. However, there is a lack of systematic, quantitative insights into the evolutionary characteristics of floor fracture networks, as well as their impacts on the stress redistribution and rock stability of coal seam floors, during hydraulic fracturing.Methods This study aims to address the challenge that is prone to cause severe damage to the floor rock masses. First, a coal seam floor was considered a saturated porous medium containing multi-scale fractures based …