Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Physical Sciences and Mathematics

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 811 - 840 of 40887

Full-Text Articles in Entire DC Network

Assessing Hyperlocal And Local Air Quality Through Passive Samplers And Low-Cost Monitors, Yan He Apr 2026

Assessing Hyperlocal And Local Air Quality Through Passive Samplers And Low-Cost Monitors, Yan He

McKelvey School of Engineering Graduate Student Theses & Dissertations

Air pollution is a major environmental health concern and has been associated with respiratory disease, cardiovascular morbidity, metabolic disorders, premature mortality, and additional adverse health outcomes. Air pollution often exhibits substantial variability at fine spatial scales, yet conventional regulatory monitoring networks are too sparse to resolve neighborhood-level exposure gradients that may exist in many urban and rural communities. Hyperlocal differences in pollutant concentrations—driven by local emission sources, land use characteristics, atmospheric chemistry, and meteorological conditions—can lead to systematic differences in long-term exposure among populations living only short distances apart. Improving exposure characterization therefore requires dense monitoring strategies and spatial modeling …


Revisiting Visualization Literacy: What Standardized Assessments Reveal And Conceal Across Instruments, Cultures, And Ai Systems, Saugat Pandey Apr 2026

Revisiting Visualization Literacy: What Standardized Assessments Reveal And Conceal Across Instruments, Cultures, And Ai Systems, Saugat Pandey

McKelvey School of Engineering Graduate Student Theses & Dissertations

Data visualizations are now a primary medium for public communication, scientific reasoning, and decision-making. By transforming complex data into accessible graphical forms, visualizations are widely assumed to make information comprehensible to broad audiences. Yet the ability to accurately read, interpret, and critically evaluate a visualization, what researchers call visualization literacy, is neither uniform nor universal. It is a learned, multidimensional skill shaped by prior exposure, educational opportunity, and context. While the field has developed standardized instruments to measure visualization literacy, these tools were built under narrow assumptions: participants are typically paid, English-speaking, and recruited from Western online panels. When any …


Artificial Intelligence, Synthetic Media, And The Criminal Justice System, Jeffrey J. Jacobs Apr 2026

Artificial Intelligence, Synthetic Media, And The Criminal Justice System, Jeffrey J. Jacobs

Doctoral Dissertations and Projects

Artificial intelligence (AI) technologies continue to evolve at an exponential pace, and their utilization of synthetic media in criminal activity presents both unprecedented opportunities and significant challenges for criminal justice systems. This dissertation explores the intersection of AI-driven synthetic media crime and the U.S. criminal justice system, identifying how such technologies are being utilized in criminal activity and evaluating the system’s capacity to adapt. This study uses a longitudinal, mixed-methods research design; it also collects and analyzes data from law enforcement agencies, AI developers, and cybersecurity experts to forecast future crime trends and assess the efficacy of current justice system …


Drug Risk Knowledge Discovery For Western Medicines Based On Knowledge Graph Link Prediction, Jianxiang Wei, Ma Hengyuan Ma, Yuehong Sun, Wenwen Du, Letian Hu Apr 2026

Drug Risk Knowledge Discovery For Western Medicines Based On Knowledge Graph Link Prediction, Jianxiang Wei, Ma Hengyuan Ma, Yuehong Sun, Wenwen Du, Letian Hu

Journal of Scientific Information Research

[Purpose/significance] The risk information contained in drug instructions is usually incomplete, and some new adverse reactions can only be discovered in actual clinical use. This paper proposes an information organization and knowledge discovery method for pharmacovigilance, in order to timely and accurately identify missing risk knowledge in drug instructions. [Method/process] Drug instructions of 8 152 Western medicines are collected as the research data; On the basis of ontology construction, data annotation, and model training, the UIE model is used to jointly extract entity and relationship triplets from the research data; A new knowledge graph link prediction method CompGCN-RotatE, is proposed, …


Coexistence Of“Emotion”And“Rationality”:Analysis Of The Impact Mechanism Of Frequent Reversal Events On The Evolution Of Online Public Opinion, Liqiang Wang, Xueqi Li, Yixian Wang Apr 2026

Coexistence Of“Emotion”And“Rationality”:Analysis Of The Impact Mechanism Of Frequent Reversal Events On The Evolution Of Online Public Opinion, Liqiang Wang, Xueqi Li, Yixian Wang

Journal of Scientific Information Research

[Purpose/significance] In recent years, frequent reversal events have negatively impacted the online media environment, leading to an increasing number of skeptical voices during the evolution of public opinion.These doubts are no longer merely emotional outbursts but also involve rational understanding of the event's authenticity. This study aims to gain a deeper understanding of this phenomenon and attempts to reveal the impact mechanism of frequent reversal events on the evolution of online public opinion. [Method/process] Through surveys and computer simulation experiments, the study analyzes various elements such as individuals, media environment, and evolution patterns in online public opinion,then according to the …


Research On Temporal Knowledge Graph Completion Method For Emergent Events Based On Bigru And Graph Contrastive Learning, Peng Wu, Zhenyu Lu, Xuechen Zhang Apr 2026

Research On Temporal Knowledge Graph Completion Method For Emergent Events Based On Bigru And Graph Contrastive Learning, Peng Wu, Zhenyu Lu, Xuechen Zhang

Journal of Scientific Information Research

[Purpose/significance] During emergencies, social media short texts contain critical information but are heavily interfered with by noise. Traditional static knowledge graph completion techniques struggle to effectively address their dynamic evolution and data sparsity issues, making it imperative to introduce temporal modeling methods. [Method/process] This study proposes a dynamic completion framework that combines the temporal feature capture capability of Bidirectional Gated Recurrent Units (BiGRU) with the noise-resistant representation learning advantages of Graph Contrastive Learning (GCL). At the completion level, the ConBiTE method is introduced, which captures temporal dependencies through self-attention mechanisms and BiGRU, while leveraging GCL to enhance the completion of …


Intermediate-Scale Outflow Dynamics Of Eta Carinae, Edmund J. Garcia, Matthew C. Fleenor Apr 2026

Intermediate-Scale Outflow Dynamics Of Eta Carinae, Edmund J. Garcia, Matthew C. Fleenor

Departmental Honors & Graduate Capstone Projects

η Carinae (η Car) is a binary system, with the larger star being an extremely massive, luminous blue variable (LBV) beyond the Eddington Limit. Surrounding the η Car system, numerous multi-wavelength imaging campaigns reveal axisymmetric structures with the expanding bipolar Homunculus Nebula (¡1 pc). In combination with the episodic eruptive history of the η Car system, our initial intermediate-scale imaging revealed further axisym- metric structures (1-5 pc). To gain a more expansive view of how the small scale structure connects to panoramic imaging of the η Car region, we constructed a deep, optical, narrowband mosaic of 189 images utilizing the …


Ticking Toward Security: Practical Source Authentication For The Precision Time Protocol, Alexander Gebhard Apr 2026

Ticking Toward Security: Practical Source Authentication For The Precision Time Protocol, Alexander Gebhard

Dissertations (1934 -)

The convergence of Information Technology (IT) and Operational Technology (OT) in Industry 4.0 environments has greatly expanded the attack surface of critical infrastructure systems. Legacy industrial protocols originally intended for use only in isolated networks are now exposed across interconnected systems. This interconnectivity enables adversaries to target power grids, manufacturing plants, and other critical systems with increasing sophistication. Although vendors have retroactively introduced security extensions to industrial protocols such as EtherNet/IP and OPC Unified Architecture (OPC UA), the adequacy and practical feasibility of these security measures remain understudied. This dissertation advances the security of industrial protocols through three main contributions. …


Insertion Of Noble Metal Free Cathodic Catalyst Layer With Fe-N-C Catalyst For Boosted Performance Of Pemfc, Shi Zhou, Muhammad Tariq, Asif Nadeem Tabish, Muhammad Salman, Fan-Di Ning, Muhammad Rayyan Tayyab, Ran-Ran Peng, Meng-Geng Hao, Wen-Mu Li, Xiao-Chun Zhou Apr 2026

Insertion Of Noble Metal Free Cathodic Catalyst Layer With Fe-N-C Catalyst For Boosted Performance Of Pemfc, Shi Zhou, Muhammad Tariq, Asif Nadeem Tabish, Muhammad Salman, Fan-Di Ning, Muhammad Rayyan Tayyab, Ran-Ran Peng, Meng-Geng Hao, Wen-Mu Li, Xiao-Chun Zhou

Journal of Electrochemistry

Economical Fe-N-C catalysts are considered as promising alternatives to platinum group metal catalysts for proton exchange membrane fuel cells (PEMFCs). Despite exhibiting robust activity on rotating disk electrodes, their performance within membrane electrode assemblies often experiences limitations, such as decreased O2 diffusion, high H2O2 formation, low proton conduction, and a lower electron transfer number. In this study, key factors, including proton transport, electron conduction, and gas diffusion within air-breathing PEMFCs, have been investigated by adjusting cathode catalyst layer (CCL) compositions. From the experimental results, the optimal peak power density was obtained when the loading of Fe-N-C …


Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc. Apr 2026

Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Final Unreclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc. Apr 2026

Final Unreclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Solarvale: Exploring Australian Ecology And Culture Through Serious Game Design, Ping-I (Adam) Ho, Elliot Birch Apr 2026

Solarvale: Exploring Australian Ecology And Culture Through Serious Game Design, Ping-I (Adam) Ho, Elliot Birch

Imaginings: creative practice and inquiry

This research examines how a serious game (Gee, 2007): Solarvale: Tale of the Sun Root (Birch et al., 2024), developed by students from SAE University College addresses the importance of ecological conservation and cultural awareness specifically in relation to the Australian landscape. While some Australian serious games, such as Catchment Detox (2008), Paperbark (2018), and Bleached Az (2019) engage with similar themes, few titles integrate storytelling with interactive ecological environments and cultural awareness in a way that encourages players to reflect on their own role and actions—which is the central focus of Solarvale. Drawing on the concepts from serious …


Isolation, Identification And Antibiotic-Resistance Profiling Of Bacteria Isolated From Mobile Phone Surfaces In Karbala., Kawkab Abdullah Alsaadi, Zahraa Raheem Murshidy, Dhuha Ali Hussein, Sura Abd Ali Kadhim, Kawakib Aboudi Hanoon Apr 2026

Isolation, Identification And Antibiotic-Resistance Profiling Of Bacteria Isolated From Mobile Phone Surfaces In Karbala., Kawkab Abdullah Alsaadi, Zahraa Raheem Murshidy, Dhuha Ali Hussein, Sura Abd Ali Kadhim, Kawakib Aboudi Hanoon

Karbala International Journal of Modern Science

Due to the diverse environments that mobile phones are exposed to via human handling they become reservoirs of microorganisms. The objective of the current study was to determine the level and character of bacterial contamination on mobile phones by identifying bacterial strains, and the degree of antimicrobial susceptibility. A cross-sectional study was conducted from April to July 2025 where phones belonging to 115 individuals were randomly chosen from various departments and units at Kerbala University and swabbed. The VITEK 2 automated system was used to identify bacterial taxa and test for antimicrobial susceptibility, and 50 of the swabs exhibited bacterial …


The Intersection Of Visual Communications, User Experience, & Design Theory: A Case Study With The Dog Spaw, Jessica Miltner Apr 2026

The Intersection Of Visual Communications, User Experience, & Design Theory: A Case Study With The Dog Spaw, Jessica Miltner

Honors Projects

This project explored the intersection of visual communication, user experience, and design theory, focusing on researching design and UX principles and applying them in a real-world case study with The Dog Spaw from Celina, Ohio. The project resulted in a redesigned website that aims to influence user behavior by improving perceptions of trust, professionalism, brand consistency, and ease of use, and by examining how these perceptions, in turn, influence user action.


Writing As A Process Of Inquiry In Autoethnography For Meaning-Making: Reflections And Some Points For Consideration, Niroj Dahal Apr 2026

Writing As A Process Of Inquiry In Autoethnography For Meaning-Making: Reflections And Some Points For Consideration, Niroj Dahal

The Qualitative Report

This article explores writing as a process of inquiry and meaning-making in the autoethnographic tradition, offering reflections on the recursive, emergent, and dialogical/dialectical nature of writing, along with some points for consideration. Drawing on perspectives from qualitative research and narrative inquiry (Riessman, 2008), I argue that autoethnographic writing serves as a method of inquiry and/or discovery, generating ontological, epistemological, and axiological-driven cultural meaning that functions as a site of reflection, interrogation, and re-storying of lived experiences. This recursive, often messy, and reflexive act allows researchers to excavate, analyze, and interpret their lived experiences. Rather than viewing writing as a final-stage …


Programmable Metal−Organic Complex Arrays With Precisely Controlled Metal Sequences As Tunable Multinuclear Scaffolds, Ahmed Alzamly, Sajid Ali Apr 2026

Programmable Metal−Organic Complex Arrays With Precisely Controlled Metal Sequences As Tunable Multinuclear Scaffolds, Ahmed Alzamly, Sajid Ali

Faculty Scholarship

Metal−Organic Complex Arrays (MOCAs) offer a modular framework for creating multinuclear systems with precise control over metal ion identity and sequencing at the molecular scale. This structural accuracy allows researchers to investigate how specific metal arrangements dictate cooperative phenomena, such as catalytic efficiency, electronic interactions, and photophysical responses. Recent breakthroughs in synthetic strategies  including orthogonal protection and periodic metalation have enabled the fabrication of highly predictable heterometallic structures. This Review explores the fundamental principles of MOCAs’ sequence control, contemporary fabrication techniques, and the relationship between metal placement and emergent properties. Additionally, it examines applications of MOCA in catalysis, sensing, and …


2026 - The Thirtieth Annual Symposium Of Student Scholars Apr 2026

2026 - The Thirtieth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the 30th Annual Symposium of Student Scholars, held on April 22-24, 2026. Includes abstracts from the presentations and posters.


Table Of Contents, The Editors Apr 2026

Table Of Contents, The Editors

Coal Geology & Exploration

No abstract provided.


Evaluation And Research Progress Of Co2 Sequestration In Deep Coal Seams, Xiong Yucan, Xu Shi’Ang, Zhang Pingsong, Lu Haifeng, Jia Yunzhong, Ge Binbin, Li Baiqiang, Liu Chang, Lei Jian, Fu Wenyu Apr 2026

Evaluation And Research Progress Of Co2 Sequestration In Deep Coal Seams, Xiong Yucan, Xu Shi’Ang, Zhang Pingsong, Lu Haifeng, Jia Yunzhong, Ge Binbin, Li Baiqiang, Liu Chang, Lei Jian, Fu Wenyu

Coal Geology & Exploration

Background With increasing pressure for global carbon emission reduction, geologic CO2 sequestration has emerged as a critical technical approach to achieving the goals of peak carbon dioxide emissions and carbon neutrality. Owing to their high CO2 adsorption capacity and favorable sealing conditions, deep coal seams are considered one of the most promising media for CO2 sequestration, following saline aquifers and depleted hydrocarbon reservoirs. Therefore, the exploitation and utilization of deep coal seams hold significant strategic importance for the green, low-carbon transformation of the coal industry. Methods Based on literature analysis and a review of outcomes from cutting-edge …


Mine Data Fusion Technology Based On Multi-Feature Joint Decision Making, Han Shanshan, Zhang Jifeng, Fan Tao, Liu Qiang, Song Xiaojiao, Qi Zhipeng, Zheng Hangzhou Apr 2026

Mine Data Fusion Technology Based On Multi-Feature Joint Decision Making, Han Shanshan, Zhang Jifeng, Fan Tao, Liu Qiang, Song Xiaojiao, Qi Zhipeng, Zheng Hangzhou

Coal Geology & Exploration

Background In the field of geological exploration of coal mines, methods such as in-seam seismic exploration, the transient electromagnetic method, and audio-frequency electrical penetration offer unique technical advantages. However, each of these methods can only reflect a single physical property of a medium, suffering from limitations including the one-sidedness of information and the multiple solutions of interpretations, thus failing to adapt to the new situations of current coal mine exploration. Multi-source data fusion promotes a technological development by leaps from one-sided detection to comprehensive analysis through mechanisms of information complementation, feature enhancement, and field-source integration. Therefore, this technology can enhance …


Exploring The Vertical Heterogeneity Of Extremely Thick Aquifers In Coal Mines Through Layered Fine-Scale Pumping Tests, Guo Xiaoming Apr 2026

Exploring The Vertical Heterogeneity Of Extremely Thick Aquifers In Coal Mines Through Layered Fine-Scale Pumping Tests, Guo Xiaoming

Coal Geology & Exploration

Objective Extremely thick aquifers in mining areas typically exhibit strong heterogeneity and high water yield. Therefore, they are prone to cause severe water inflow in mines and induce water disasters, representing a major factor affecting the mining safety of numerous mines in China. However, the vertical heterogeneity of these aquifers remains poorly understood, emerging as a primary bottleneck in the prevention and control of such water hazards. Methods To scientifically reveal the vertical heterogeneity characteristics of extremely thick aquifers, this study investigated the extremely thick Luohe Formation aquifer in a coal seam roof of a representative coal mine in the …


Exploring Water Migration Patterns In Reconstructed Soil Layers For Waste Dumps Of Open-Pit Coal Mines Based On Ct Scanning, Fan Tingyu, Zhang Xinghui, Lu Akang, Yang Changde, Wang Shun, Wang Xingming, Sun Xueliang, Ji Quancai Apr 2026

Exploring Water Migration Patterns In Reconstructed Soil Layers For Waste Dumps Of Open-Pit Coal Mines Based On Ct Scanning, Fan Tingyu, Zhang Xinghui, Lu Akang, Yang Changde, Wang Shun, Wang Xingming, Sun Xueliang, Ji Quancai

Coal Geology & Exploration

Objective In the arid regions of western China, the ecological restoration of waste dumps within open-pit coal mines plays a key role in green mine construction, while creating a suitable soil profile structure serves as a prerequisite for the ecological restoration.Methods This study investigated the reconstructed soils with a three-layer sponge-like structure consisting of the topsoil, sandy-soil, and mudstone layers for the waste dump of the Hongshaquan open-pit coal mine in Xinjiang. Using computed tomography (CT) scanning, a three-dimensional (3D) pore network model (PNM), and water migration simulation, this study systematically analyzed the pore structures and water migration characteristics …


Joint Inversion For Heat Transfer Parameters Of Porous Media With Geothermal-Seepage Coupling Based On A Physics-Informed Neural Network, Zhang Xiao, Yang Duoxing, Cong Lin, Cheng Yimei, Zhang Lianzhong Apr 2026

Joint Inversion For Heat Transfer Parameters Of Porous Media With Geothermal-Seepage Coupling Based On A Physics-Informed Neural Network, Zhang Xiao, Yang Duoxing, Cong Lin, Cheng Yimei, Zhang Lianzhong

Coal Geology & Exploration

Background The thermal diffusivity and vertical seepage velocity of porous media are critical to characterizing the mechanisms underlying subsurface heat transfer. These two parameters are typically determined through inversion using temperature data since they are difficult to measure directly. Fiber-optic distributed temperature sensing (FO-DTS) can yield high-resolution, continuous temperature profiles, providing data for parameter identification. However, conventional numerical inversion suffers from limitations such as mesh dependency and sensitivity to initial values when used to process continuous monitoring data. Methods This study proposed a joint geothermal parameter inversion method that integrates FO-DTS data with a physics-informed neural network (PINN). Specifically, the …


Program And Proceedings, The Nebraska Academy Of Sciences 1880–2026: 146th Anniversary Year, One Hundred-Thirty-Sixth Annual Meeting Apr 2026

Program And Proceedings, The Nebraska Academy Of Sciences 1880–2026: 146th Anniversary Year, One Hundred-Thirty-Sixth Annual Meeting

Nebraska Academy of Sciences: Programs and Proceedings

Program and abstracts of the proceedings for the Nebraska Academy of Sciences 136th annual meeting, 2025

Sessions

Aeronautics and Space Science

Anthropology

Biological and Medical Sciences

Earth Sciences

Ecology, Sustainability, and Environmental Science

Physics and Engineering

General Poster Session

2026 Maiben Lecture: Shifting Extremes: Understanding Nebraska’s Changing Climate and Preparing for What Lies Ahead, Deborah Bathke

2026 Friends of Science Awards: Julie Shaffer and Irina Filina

2026 C. Bertrand and Marian Othmer Schultz Colleaguate Schoalrship Award: Piper Ryschon and Bryce Reeson

In Memoriam: Paul Royster


Click Reactions With Surface-Bound Phosphonate Films Toward An Electrocatalytic System For Carbon Dioxide Reduction, Iaroslavna Kovalenko, Emma J. Goehner, K. Nicole Crowder Apr 2026

Click Reactions With Surface-Bound Phosphonate Films Toward An Electrocatalytic System For Carbon Dioxide Reduction, Iaroslavna Kovalenko, Emma J. Goehner, K. Nicole Crowder

Research and Creativity Symposium

One way to electrochemically reduce CO2 is to use modified electrode surfaces with bound transition-metal electrocatalysts. Optimal conditions for modifying copper surfaces with a 1.0 mM solution of (2-azidoethyl) phosphonic acid in acetone have been identified, forming a self-assembled monolayer (SAM) via the tethering by aggregation and growth (T-BAG) method. The SAM protects the copper electrodes from oxidation or side reactions on the copper surface. The copper-catalyzed azide-alkyne cycloaddition (CuAAC) click reaction between the terminal azide group on the phosphonate and the terpyridine ligand has been successfully carried out on the copper surface. This terpyridyl ligand was then used …


Sustainable Ethanol Production From Agricultural Waste, Eva Shealy, Bre Venditti, Muath Alharbi, Jacob Dymock Apr 2026

Sustainable Ethanol Production From Agricultural Waste, Eva Shealy, Bre Venditti, Muath Alharbi, Jacob Dymock

Chemistry and Chemical Engineering Student Publications

This project presents a commercial-scale process which converts waste corn stover into fuel grade ethanol through syngas fermentation. By integrating thermochemical conversion with microbial processing, the design explores an innovative pathway for ethanol production, resulting in a lower-impact alternative to traditional processes.


Plant Growth Promoting Phenotypes Of Fungal Isolates From The International Space Station, Shane Doyle, Frances A. Edmonson Apr 2026

Plant Growth Promoting Phenotypes Of Fungal Isolates From The International Space Station, Shane Doyle, Frances A. Edmonson

Ocean Engineering and Marine Sciences Student Publications

  • In situ (on site) space crop production is vital for sustainability and dietary health of astronauts. 
  • We hypothesize that International Space Station (ISS) derived fungal isolates will stimulate plant growth and express PGP phenotypes.
  • Eleven space-viable fungi were screened via phenotypic testing to identify plant growthpromoting (PGP) activity.
  • Prior research has been conducted solely with ISS derived bacteria, while ISS fungi are unexplored, which could reveal new or improved symbiotic relationships and growth factors.


Repurposing An Old Pc Into A Self-Hosted Cloud And Media Server, Riley Biggins Apr 2026

Repurposing An Old Pc Into A Self-Hosted Cloud And Media Server, Riley Biggins

Honors Theses

Commercial cloud platforms rely heavily on subscription models, so everyday users fall into a "cloud trap" summarized by perpetual fees, forfeited privacy, and a lack of true asset ownership. At the same time, functioning consumer electronics get discarded as e-waste when they fail to meet the hardware requirements of modern operating systems. This project presents a sustainable and cost-effective alternative to both issues by repurposing a 2017 HP Pavilion laptop into a personal cloud and media server.

Despite severe hardware constraints, my software architecture rivals the utility of paid services. By replacing Windows with a headless installation of Ubuntu Server, …


Draft Uniform Federal Policyquality Assurance Project Plan Addendum, Hydrogeologic, Inc. Apr 2026

Draft Uniform Federal Policyquality Assurance Project Plan Addendum, Hydrogeologic, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Investigating The Bioactivity Of Novel Β-Diketonate Complexes, Celeste Remolina, Dylan Wolfe Apr 2026

Investigating The Bioactivity Of Novel Β-Diketonate Complexes, Celeste Remolina, Dylan Wolfe

Research & Creative Achievement Day

Ruthenium β-diketonate complexes have emerged as promising chemotherapeutics due to their selective bioactivity against tumors. We assessed the bioactivity of novel synthesized ruthenium β-diketonate complexes on human cancer cells as well as wild-type cells. Using cell growth assays, we screened candidate ruthenium complexes and determined the IC50 value for effective candidates. Here we present a model for ruthenium-mediated growth inhibition