Digital Commons Network^™

The Formulation And Physical Analyses Of Antibiotic Aerosol Foams For The Development Of Potential Topical Dermatologicals, Joseph Alexander Woelfel

University of the Pacific Theses and Dissertations

Within the last two decades the consumer market has been deluged with a diversity of aerosol products. The acceptability and utility of these products is reflected by the number found in the household and industry.

An antibiotic foam would obviate the necessity of manual application as is the case with the ointment or cream type products. Therefore, there would be less irritation to the already traumatized or infected sites by mechanical, chemical, or bacterial vectors.

Thus, the objective of this research will be to systematically develop suitable aerosol foam systems which contain therapeutically effective topical antibiotics with a subsequent evaluation …

Spectrophotometric And Microbiological Determination Of The Stability Of Sodium Ampicillin As Affected By Ph, Enrico Frank Raffanti

University of the Pacific Theses and Dissertations

The specific purpose of this investigation was to determine the effect of pH on the stability of ampicillin sodium for injection. Then, to correlate this information, a pH profile may be established to predict chemical stability with ampicillin sodium alone or when other drugs may be included in the admixture. With a pH profile the pharmacist could predict the length of time after which more than a 10 percent loss of activity would occur. Stability measurements were to be accomplished through a microbiological assay after adding ampicillin sodium to different buffer solutions. At the end of four hours, eight hours, …

The Thermal Rearrangement Of Triarylacetonitrile Oxides., Leslie Wayne Gibbs

University of the Pacific Theses and Dissertations

This research is a detailed study of the rearrangement of triarylacetonitrile oxides to the corresponding triarylmethylisocyanates. The kinetics of the rearrangement of triphenylacetonitrlle oxide was followed by infrared absorption spectroscopy using the peak due to the N-0 stretching (1307cm^-1). A study, both, using the differential method (i.e., a plot of the logs of the initial slopes vs. the log of the concentration) and a check of the integrated forms of the rate expressions to determine which gave a constant value for the rate constant showed that the reaction is first order.

From measurements of the rate constant, k, …

Synthesis And Reactions Of Benzyl 2-Bromo-2-Deoxy Hexoses, Terry Cady Tompkins

University of the Pacific Theses and Dissertations

The purpose of this study is to show that the method just proposed can be used for the synthesis of 2-halo benzyl glycosides. And these derivatives can be used to synthesize biologically interesting compounds which were not previously attainable using the 2-halo-2-deoxy methyl glycosides which are currently available.

Time Resolved Measurements Of Droplet Growth In A Wilson Cloud Chamber, Michael Anthony Vietti

Doctoral Dissertations

"The growth rates of water drops in a Wilson expansion cloud chamber are measured with air, argon and helium as the carrier gas, in the size range of .5 to 10 microns. The drops growing in the supersaturated chamber exhibit oscillations in the scattered intensity as predicted by Mie theory. Scattered intensity is measured at 30 degrees to the He-Ne laser beam. Supersaturation ratios during growth range from S =1.2 to S = 3.5 for all three gases. The initial temperature is measured and the pressure is monitored continuously so that droplet growth theory can be compared with experiment. Three …

A Study Of Some Complexometric Titrations In Nonaqueous Solvents, Ngo The Hung

Masters Theses

"Complexometric titrations of calcium, zinc and lead with polyaminocarboxylic acids: ethylenediaminetetraacetic acid (EDTA), 1,2-diaminocyclohexanetetraacetic acid (DCTA), ethyleneglycol-bis(2-aminoethylether)tetraacetic acid (EGTA) and tetraethylenepentamine (tetren) have been investigated and compared in the following organic solvents: methanol, dimethyl formamide, dimethyl sulfoxide and methyl ethyl ketone. Various end point detection methods have been used: direct visual titration with metallochromic indicators and instrumental detection by photometry, potentiometry (mercury electrode and lead ion selective electrode) and amperometry. Calcium, zinc and lead can be determined up to trace levels (ppm) under specific conditions. A concrete application of this thesis is the determination of zinc or calcium in a …

Studies On The Mechanism Of Action Of Nerve Growth Factor., D. (Daniel) B. Hier, B. G. Arnason, M. Young

Chemistry Faculty Research & Creative Works

No abstract provided.

The Scattering Of Elastic Waves By Void Cavities, Jerry Lee Davis

Doctoral Dissertations

"Elastodynamic multipole theory, the theory of least squares, and the theory of integral representation of solutions are employed in solving certain problems involving an elastic solid containing a source and a scatterer. Both the source and scatterer are of finite geometrical extent; they occupy non-intersecting regions. The source is separable, i.e., its mathematical specification consists of an arbitrary vector function of position multiplied by a time function, which is further assumed to be a sinusoid. The scatterer emphasized is a finite void cavity of arbitrary shape; however, scatterers composed of rigid material may also be treated. The calculation of a …

The Average Dissipation Curve Of An Attenuative Layered Earth Medium, Joong Hee Chun

Doctoral Dissertations

"A feasible method of estimating the attenuative properties of a layered earth medium from a reflection seismogram has been developed. An average attenuation factor of n layers in the least squares sense is designated as ß and its usefulness in real applications is investigated. Techniques of extracting dissipation factors from both noise free and noisy reflection seismic traces are discussed. In order to describe the change of the factors with an increase of depth, an average dissipation curve the form of which is similar to the average velocity of layered medium is also introduced. Both the ß and the average …

Capillary-Diffusion And Self-Diffusion Of Liquid Water In Unsaturated Soils, Ronald E. Phillips, V. L. Quisenberry Jr.

KWRRI Research Reports

Capillary-diffusion coefficients were measured by use of inflow and outflow methods. With both methods the capillary-diffusion coefficients decreased very rapidly with decreasing water content. The lighter textured soils were found to have the higher diffusion coefficients over the entire moisture content range studied, 0 to 1 bar tension.

Self-diffusion coefficients were measured over a moisture content range from air dryness to saturation using ³H as a tracer of water. Each of the soils gave the same diffusion characteristics when the self-diffusion coefficients were expressed as a function of either water content or average number of water layers on the …

The Reduction Of Carbonyl Compounds By Sodium Naphthalenide, James Stinnett

Masters Theses & Specialist Projects

The purpose of this investigation was to study the reactions of sodium naphthaienide with various aromatic carbonyl compounds, particularly aromatic aldehydes and ketones. Although sodium naphthalenide was first investigated in 1936 by Scott et al, the synthetic utility of this alkali metal adduct in organic chemistry has only recently been explored. It was thought that sodium naphthalenide might provide a synthetic advantage, as compared to sodium metal solutions, in the reduction of carbonyl functions to their respective glycols and/or alcohols.

The Ias Bulletin, V5n6, November 1971, Iowa Academy Of Science

IAS Bulletin

In this issue:

--- Officers, Directors, and Section Chairmen, 1971-72
--- An Open Letter from the President to the Members of the Iowa Academy of Science
--- Manuscripts for the Proceedings Invited
--- News from the Fall Directors' Meeting
--- Plans for 1972 Spring Meeting Shaping Up
--- Call for Papers for the 1972 Spring Meeting
--- Archeology Section Now Anthropology Section
--- What Ever Became of the Articulation Effort?
--- Future Meetings of the Academy
--- Geology Monograph Widely Distributed
--- New Officers of ISTS
--- Special Summer Study Opportunity Available
--- Do-It-Yourself Kit for Activists
--- 56% of …

Water Resources News, Volume 3, No. 9, November 1971

Water Current Newsletter

Program for the 1972 Interdisciplinary Seminar on Water Issues
Simulation of Groundwater Systems
Summer Short Course Planned
Recyling of Water
OSW Awards Freezing Plant Design Contract
Cloud-Seeding Program
Water Rights Study
"Turn-Key" Approach Proposed for Construction of Waste Treatment Plants
Water Quality Guidelines for Nation Being Updated by NAS for EPA
Nebraska Water Resources and Irrigation Development Seminar for the 1970s
EPA Names New Head of Solid Waste Programs Office
Symposium on Costs of Waster Pollution Control
Research Need
Symposium on Watershed Management
EPA Revising Regulations for Grants and Contracts
Internships in Science and Engineering

Ua77/1 Western Alumnus, Vol. 40, No. 2, Wku Alumni Relations

WKU Administration Documents

Quarterly magazine created for WKU alumni. Regular features are Hilltopics, Sports, Alumni Newsgrams and Notes and In Memoriam. This issue includes:

• Graduate School (College) is On Its Way
• Evening Class is Thataway
• The Hilltopper Hundred to the Rescue
• ETV - Keep Watching, It's All in Color
• Student Interns Learn How Government Works
• Significant Statements: The New Year Begins
• Good News for Fishermen: Reservoir Research
• There it Was! Your Homecoming - 1971
• Performing Arts Illuminate the Campus Scene
• Discovery 1 - Uncovering the Kentucky of Antiquity
• Discovery 2 - Reviving the Heritage of Kentucky
• Discovery 3 - The Intercultural Studies Program …

A Preliminary Ecological Study Of Areas To Be Impounded In The Salt River Basin Of Kentucky, Louis A. Krumholz

KWRRI Research Reports

This report covers work that is an extension of Project No. A-019-KY. A series of 25 sampling stations was established in the mainstream and tributaries of the Salt River that extend from the source of the stream in Boyle County to a few miles below the site of Taylorsville Darn in Spencer County. Sampling for water chemistry and biota was carried out semimonthly. Data on temperature, oxygen, depth, and discharge, along with analyses for cations (Ca, Mg, Fe, Mn) and anions (PO₄, NO₃, NO₂, CO₃, HCO₃) have been accumulated and …

A Study Of A Divalent Cation-Selective Electrode, William Stanhope Ryan Jr.

Master's Theses

The ion-selective membrane electrode, recently introduced commercially, has shown excellent promise as a tool for determining ionic activities and concentrations in solution. It was the intent of the author to study the Orion divalent cation-selective electrode with two objectives.

The first objective of this research was to characterize the response of the divalent cation-selective electrode to calcium and magnesium ions in aqueous solutions. The effect of anions, monovalent cations; and pH upon this response was investigated. An examination was made of the response of this electrode to other divalent cations and of the effect of organic solvents on the membrane …

A Kinetic Analysis Of The Iodination Of Pyruvic Acid And Pyruvate Esters, Mohamed M. Fahmi Hegazi

All Master's Theses

In the present work the relative rates of iodination of pyruvic acid and ethyl and methyl pyruvate have been compared at 25.0° C. These studies allow the determination of the respective free energies of activation for these processes. Measurements have also been carried out at various temperatures to determine the enthalpies and entropies of activation for the spontaneous and base catalysed iodinations of these pyruvate systems. The present thesis also includes a comparison of the solvent deuterium isotope effects associated with the spontaneous rate of iodination of pyruvic acid and the alkyl pyruvates. Also, the catalytic rate coefficients associated with …

Analysis Of Littoral Transport By Wave Energy: Cape Henry, Virginia To The Virginia, North Carolina Border, Zvi Henry Weinman

OES Theses and Dissertations

An investigation of the rate of littoral transport by an analysis of wave energy for the area from Cape Henry, Virginia to the Virginia, North Carolina border is made. Wave refraction diagrams are done by digital computer. Total upcoast (northerly) transport is determined to be 2.05 x 10⁶ yds³/year. Total downcoast (southerly) transport is determined to be 1.07 x 10⁶ yds³/year. Net transport is determined to be 9.8 x 10⁵ yds³/year in an upcoast (northerly) direction. The values obtained are compared with those of similar areas. The general efficacy of the …

Unsteady Flow Toward Partially Penetrating Artesian Wells, Y. H. Huang

KWRRI Research Reports

A numerical method programmed for a high-speed computer was developed for determining the drawdown around an artesian well. A salient feature of the program is that it can be used for both fully and partially penetrating wells in either infinite or finite aquifers. The method Involves the application of finite difference equations to the well-known heat equation using a graded network. A comparison of the finite difference solutions with those obtained from the close-form formulas of Muskat, Theis, and Hantush indicates the validity of the method. A comparison between the finite difference solutions and the drawdowns measured on a sand …

Water Resources News, Volume 3, No. 5, May 1971

Water Current Newsletter

Congratulations Doane College
OWRR Announces Fiscal Year 1972 Title II Water Resources Research Program
Economic Analysis of Water Projects
New Federal Department of Natural Resources
Research and Development Sources Sought
Water Quality Guidelines

A Calorimetric Study Of Metal Ion Cyclic Polyether Interaction :|Bi. Cation Binding Properties Of Macrocyclic Polyethers In Aqueous Solution As A Function Of Temperature ; Ii. Effect Of Solvent Dielectric Constant On The Binding Properties Of Cyclic Polyethers For Na[Superscript +] And K[Superscript +], Dennis Pershing Nelson

Theses and Dissertations

The complexation properties of the two isomers of the cyclic polyether dicyclohexyl-18-crown-6 are examined in aqueous solution for a series of metal ions at various reaction temperatures. The results are discussed in terms of size relationships and salvation characteristics of both polyether and metal ions. ΔCp° values are determined from the temperature dependence of the ΔH° values. A discussion of the errors involved in the determination of ΔH° from the temperature dependence of log K values is also included. Comparisons are made between the results of this study and those of a similar study by H. K. Frensdorff, E. I. …

A Comparison Of Various Teaching Methods For Patients With Chronic Obstructive Pulmonary Diseases, B. Carol Altizer, Nancy S. Bailey

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to find out whether patients with chronic obstructive pulmonary disease (C.O.P.D.) learn more from auditory or from visual teaching. Of the 30 patients in the sample, 10 used a programmed instruction booklet, 10 used a taped recording of the same programmed material and 10 were in a control group which received no specific teaching.

A pre-test was given to each of the patients who met the criteria for the study. One researcher gave the pre-test through an oral interview with the patient. After the pre-test, the patient received the teaching device assigned to him …

Using A Participating Relationship To Improve Teen-Age Unwed Mother's Self-Esteem, Linda Gail Reeves

Loma Linda University Electronic Theses, Dissertations & Projects

The study was to provide an approach to help teen-age unwed mothers increase their feelings of self-esteem and thereby attain a conceptual buffer for better coping with life. Self-esteem was defined as individual perception of the worth of oneself relative to that of significant others. The hypothesis tested was that the participating relationship a community health nurse has with a teen-age unwed mother will significantly increase the mother's self-esteem as measured by statistical Q-Sort analysis.

A convenience sample of twenty teen-age unwed mothers was obtained from referrals from San Bernardino County Health, Welfare, and Probation Departments. The girls were between …

The Effect Of Alternate Wetting And Drying On The Ammonium And Nitrite Nitrogen Transformation In Soils, Virupax C. Baligar

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Investigations were carried out to study the effect of alternate wetting and drying cycles on the mineralization, nitrification, and denitrification of soil nitrogen in two soils, in the presence or absence of added ammonium and nitrite. Soils were analyzed at the end of each drying cycle for total inorganic nitrogen, ammonium, and nitrite nitrogen. Gaseous products, i.e., ammonia, and the oxides of nitrogen (NO and NO₂) were collected in the course of drying for determination.

The drying cycles accelerated the rate of nitrogen mineralization in both soils and further increased the oxidation of applied and available ammonium. The …

Role Of Transition Metals In Nitrite Decomposition In Soil, J. S. Bajwa

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Iron and copper increased the decomposition of nitrite significantly during the first two hours of reaction when 150 parts per million (ppm) of nitrite and nitrogen was added to an acidic soil. Manganese was found to have a slight effect. There was no additional effect of the added metals after two hours reaction time.

The higher concentration of metals was not effective in catalyzing the decomposition of the added nitrite in nitrogen. All the added nitrite nitrogen was not recovered and the deficit could be due to the formation of nitrogen gas.

Influence Of Temperature Of Incubation And Type Of Growth Medium On Pigmentation In Serratia Marcescens, Robert P. Williams, Cora L. Gott, S M. Qadri, Randolph H. Scott

Faculty, Staff and Student Publications

Maximal amounts of prodigiosin were synthesized in either minimal or complete medium after incubation of cultures at 27 C for 7 days. Biosynthesis of prodigiosin began earlier and the range of temperature for formation was greater in complete medium. No prodigiosin was formed in either medium when cultures were incubated at 38 C; however, after a shift to 27 C, pigmentation ensued, provided the period of incubation at 38 C was not longer than 36 hr for minimal medium or 48 hr for complete medium. Washed, nonpigmented cells grown in either medium at 38 C for 72 hr could synthesize …

Synthesis Of Chromium Tricarbonyl Complexes Of 1,3-Diaryl-2-Propyl Methanesulfonates, Ashby French Johnson

Master's Theses

Various unsymmetrically substituted 1 , 3-dipheny l -2- propylmethanesulfonates were prepared and complexed with chromium hexacarbonyl. The major products obtained from this complexation contained one rr -complexed ring and the other ring substituted with more common groups.

Fisheries Report No 9 - The Fauna And Flora Of Monte Bello Islands, A. A. Burbidge Dr

Fisheries Research Reports

Two visits were made to the Monte Bello Islands in 1970 and 1971.

The aim of the visits was to examine the islands for the presence of native mammals and other fauna, and to explore the possibility of re-establishing fauna now extinct,

The first survey was carried out in conjunction with a more detailed examination of the Dampier Archipelago. The fisheries patrols vessel "Dampier" was used to reach the islands and as a base. Personnel were R. Johnstone (W.A. Museum), E.J. Little and J.D. Harman (crew of the "Dampier"), R.F. Dear and A.A, Burbidge, all from the Department of Fisheries …

A Study Of Productivity In Drosophila Immigrans, Lalita Helen Shenoy Waterman

University of the Pacific Theses and Dissertations

In this study it has been demonstrated that Drosophila immigrans females begin laying fertile eggs on the third or fourth day following eclosion, with productivity reaching a peak between the fifth and sixth days of adult life. A delay in mating of even four days decreases the rate as well as the volume of productivity. Based on the evidence in the literature, it is suggested that the stimulus to oviposition may be mechanical or chemical on the corpora allata via the ventral nerve cord.

The Ias Bulletin, V5n1, January 1971, Iowa Academy Of Science

IAS Bulletin

In this issue:

--- Officers, Directors, and Section Chairmen, 1970-71
--- Note from the Editor of the Proceedings
--- Survey of Interest in the Iowa Science Teachers Journal
--- 83rd Session Joint Meetings Planned
--- General Session Speakers Named
--- Governor's Budget Hearings Involve Academy Officers
--- Iowa Section of the American Association of Physics Teachers
--- Note from One of Our Older Members
--- The 137th Meeting of the AAAS, Chicago
--- ISTS Executive Committee Meeting
--- NSTA Meetings
--- Excellence in Teaching Awards
--- Action by the Social Implications Committee
--- AAAS Research Grant Funds Available
--- Questionnaire …