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Sperm Morphology In The Eastern Narrow-Mouthed Frog, Gastrophryne Carolinensis (Anura: Microhylidae), S. E. Trauth Jun 2026

Sperm Morphology In The Eastern Narrow-Mouthed Frog, Gastrophryne Carolinensis (Anura: Microhylidae), S. E. Trauth

Journal of the Arkansas Academy of Science

Studies by Scheltinga et al. (2002) and Scheltinga and Jamieson (2003) provide the most comprehensive analysis and only review of sperm morphology in Narrow-Mouthed Frogs (family Microhylidae). Of the 490+ species known to occur in this anuran family (Vitt and Caldwell 2014), only 3 are distributed in the United States (Powell et al. 2016), and 2 of these occur in Arkansas (Trauth et al. 2004). Surprisingly, sperm studies on only 12 microhylid species have been conducted (Scheltinga and Jamieson 2003), and no sperm studies are available on any North American species.


Multiple Nuclear Configurations And Microtubular Arrangements In Spermatozoa Of The Western Siren, Siren Nettingi (Caudata: Sirenidae), S. E. Trauth Jun 2026

Multiple Nuclear Configurations And Microtubular Arrangements In Spermatozoa Of The Western Siren, Siren Nettingi (Caudata: Sirenidae), S. E. Trauth

Journal of the Arkansas Academy of Science

I examined the ultrastructure of spermatozoa of the Western Siren, Siren nettingi, using transmission electron microscopy. My primary objective in this study was to elucidate, for the first time, the unique morphological complexity of biflagellated sperm in this species. This study also represents my fifth addition in a series of investigations that highlight the novel nature of all aspects of spermatogenesis in this salamander I show the basic sperm transverse and sagittal design which includes a nucleus, 2 axial fibers supporting 2 undulating membranes which have 2 axonemes residing at their terminal ends, several circular mitochondria, and several electron-dense masses. …


Binucleation And Seasonal Cycle Of Sertoli Cells In The Western Lesser Siren, Siren Nettingi (Caudata: Sirenidae), S. E. Trauth Jun 2026

Binucleation And Seasonal Cycle Of Sertoli Cells In The Western Lesser Siren, Siren Nettingi (Caudata: Sirenidae), S. E. Trauth

Journal of the Arkansas Academy of Science

I examined binucleation and the seasonal cycle of Sertoli cells in the Western Siren (Siren nettingi) using light microscopy and transmission electron microscopy. My primary objective in this study was to report, for the first time, the presence of double nuclei in Sertoli cells in a salamander. This study also represents the sixth contribution in a series of investigations that highlight the novel nature of all aspects of spermatogenesis in this unique salamander. My findings add to a growing list of extraordinary morphological and reproductive features that distinguish this salamander from all other vertebrates.


Distal Urogenital Anatomy And Epithelial Morphology In The Male Eastern Narrow-Mouthed Frog, Gastrophryne Carolinensis (Anura: Microhylidae), S. E. Trauth Jun 2026

Distal Urogenital Anatomy And Epithelial Morphology In The Male Eastern Narrow-Mouthed Frog, Gastrophryne Carolinensis (Anura: Microhylidae), S. E. Trauth

Journal of the Arkansas Academy of Science

I investigated the microanatomy of the distal urogenital system in male Eastern Narrow-Mouthed Frogs (Gastrophryne carolinensis) from a small sample (n = 5) collected in central Arkansas in April, May, and July (2021) and May 2022. Specifically, my primary goals were to elucidate the histology of the following: (1) the paired Wolffian (urogenital) ducts caudally from the kidneys to their merging with the urodeum of the cloaca, (2) the structure of seminal vesicles, and (3) the epithelial morphologies among the distal urogenital tract, the posterior alimentary canal, and the cloaca. My histological analysis confirmed the presence of …


Academy Presidents And Institutional Members, Academy Editors Jun 2026

Academy Presidents And Institutional Members, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.


Table Of Contents, Academy Editors Jun 2026

Table Of Contents, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.


Journal Of The Arkansas Academy Of Science Volume 79, Academy Editors Jun 2026

Journal Of The Arkansas Academy Of Science Volume 79, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.


A Scoping Review Of Sycophancy In Large Language Models: Operational And Theoretical Recognition, Kallen Zhou, Manning Littlejohn, Isabella Garrard Jun 2026

A Scoping Review Of Sycophancy In Large Language Models: Operational And Theoretical Recognition, Kallen Zhou, Manning Littlejohn, Isabella Garrard

Endeavors: Mississippi State Undergraduate Research Journal

As large language models (LLMs) usage grows across different domains, sycophancy, the tendency for output to align with users, is increasingly being recognized as a primary issue arising from applying LLMs into critical areas. Current research has provided a variety of theoretical definitions, mitigation techniques, and quantification for sycophancy. However, there is little to no consistency across different papers. This scoping review seeks to connect different works on LLM sycophancy by identifying themes in theoretical definitions, measurement methods, and inducement techniques of sycophancy. By analyzing 26 papers (preprints, conference proceedings, and journal articles) from arXiv, ACL Anthology, and Scopus, this …


Novel Connotations Of Green Exploration Oriented To Mine Ecological Restoration, Hu Zhenqi, Zhang Fan, Zhao Yanling, Liang Yusheng Jun 2026

Novel Connotations Of Green Exploration Oriented To Mine Ecological Restoration, Hu Zhenqi, Zhang Fan, Zhao Yanling, Liang Yusheng

Coal Geology & Exploration

Background Mineral resource exploitation inevitably causes ecological damage, while its green solution is rooted in green exploration. Currently, green exploration refers to activities aimed at avoiding, eliminating, or mitigating ecological pollution and damage caused by exploration operations, as well as those intended for the restoration of the ecosystem damaged in the exploration process. However, besides focusing on the exploration process, green exploration should provide geological guarantees for ecological restoration following resource exploitation. [Methods] In this study, the novel connotations of green exploration are proposed first. In other words, green exploration, which should be oriented to the demand for mine …


Advances In Research On Techniques For Petrographic Analysis And Tests Of Coals And Their Applications In China, Song Xiaozhong, Zhang Qun, Fan Zhangqun, Jiang Wenping Jun 2026

Advances In Research On Techniques For Petrographic Analysis And Tests Of Coals And Their Applications In China, Song Xiaozhong, Zhang Qun, Fan Zhangqun, Jiang Wenping

Coal Geology & Exploration

Background Techniques for petrographic analysis and tests of coals are critical to the accurate characterization of coals, oil, and gas, providing pivotal geological bases for coalfield exploration, formation condition investigation of coal deposits, clean and efficient coal utilization, and hydrocarbon resource evaluation. China's coal petrology commenced nearly a century ago, having progressively evolved into a key field serving the national energy strategy from the early-stage component identification and genetic investigation of coals. A standardization system suitable for the petrographic analysis and tests of coals with distinctive Chinese characteristics has been established. This system has found applications in industrial fields including …


Algorithmic Monocultures In Hiring, Rishi Bommasani, Sarah H. Bana, Kathleen A. Creel, Dan Saul Jurafsky, Percy Liang Jun 2026

Algorithmic Monocultures In Hiring, Rishi Bommasani, Sarah H. Bana, Kathleen A. Creel, Dan Saul Jurafsky, Percy Liang

Economics Faculty Articles and Research

Many employers screen job applicants with algorithms built by the same few algorithm vendors. We hypothesize that algorithmic monoculture leads to the same individuals and members of the same racial groups facing rejection. We acquire and analyze a novel dataset of 3 million applicants submitting 4 million applications where all the applications are screened by algorithms built by the same vendor. We find clear racial disparities in applicant outcomes. Of all applications submitted by Asian and Black applicants, 14.74% and 25.87% are submitted to positions that adversely impact Asian and Black applicants, respectively, according to U.S. employment discrimination standards. Individuals …


Managing Prairie Dogs On Agricultural Lands, Cory Farnsworth, S. Nicole Frey Jun 2026

Managing Prairie Dogs On Agricultural Lands, Cory Farnsworth, S. Nicole Frey

All Current Publications

While prairie dogs are an important species in the region because their burrows provide shelter for many wildlife species, they are also preyed upon by many mammals and birds. However, because of the damage they can cause to cropping and range systems, their populations may occasionally need to be controlled. After you have identified which prairie dog species you are in conflict with and the scope of the damage, you will want to decide how to manage them. This fact sheet provides information on control options and the general ecology of the three prairie dog species in Utah.


The Soil Crisis In Modern Food Systems: Rethinking Agricultural Land Use, Antonia Moure Richard Jun 2026

The Soil Crisis In Modern Food Systems: Rethinking Agricultural Land Use, Antonia Moure Richard

Journal of Food Law & Policy

Feeding a larger world while preserving the resource that makes agriculture possible—soil—poses a governance problem. By 2050, food systems must support 9.8 billion people even as prevailing practices continue to degrade soils that are non-renewable on human timescales. Technological fixes (e.g., vertical farming, hydroponics) may complement production, but they cannot substitute for soil at scale. The question that follows is simple: are current uses of soil compatible with the future needs of food systems? This article argues that without a shift in governance, short-run productivity gains are achieved by drawing down the soil asset, thereby undermining long-run food security and …


Movement Ecology And Population Dynamics Of Box-Nesting Black-Bellied Whistling-Ducks (Dendrocygna Autumnalis) In Louisiana, Katie E. Miranda Jun 2026

Movement Ecology And Population Dynamics Of Box-Nesting Black-Bellied Whistling-Ducks (Dendrocygna Autumnalis) In Louisiana, Katie E. Miranda

LSU Master's Theses

Understanding demographic and behavioral processes underlying population dynamics is essential for effective wildlife management, especially for species subject to harvest pressure or experiencing population shifts. Black-bellied Whistling-Ducks (Dendrocygna autumnalis) are currently undergoing a notable northward range expansion and are increasing in abundance across the southeastern United States, raising management concerns for both ecological and economic reasons. As a result, there is growing public support for a special Black-bellied Whistling-Duck-specific harvest season, yet little research has been conducted on this species, particularly within newly-established populations. To address this gap, I conducted this study with the goal of evaluating seasonal …


Re: Conditional Approval Letter For Butte Priority Soils Operable Unit Draft Final Leak Detection Monitoring Plan (Dated May 13, 2026), Emma Rott Jun 2026

Re: Conditional Approval Letter For Butte Priority Soils Operable Unit Draft Final Leak Detection Monitoring Plan (Dated May 13, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Advancing Data Usability, Activity Modeling, And Stability Optimization In Computational Enzyme Design, Spencer Gardiner Jun 2026

Advancing Data Usability, Activity Modeling, And Stability Optimization In Computational Enzyme Design, Spencer Gardiner

Theses and Dissertations

A grand challenge of computational biology is to computationally design, in a single pass, a protein sequence that catalyzes an arbitrary chemical reaction at a high rate under specified conditions [1]. This work details advances in three essential areas on the path to that goal: data quality, activity prediction and modeling, and stability optimization. The structure and implementation of the Allotrope Simple Model (a FAIR data format for many scientific instruments) was examined in [2], setting the stage for training deep learning models on high-quality experimental datasets from diverse sources. In [3], the limits of physics-based and deep learning tools …


Re: Conditional Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Clark Tailings Consolidated Waste Management Area (Ctcwma) Site Investigation Quality Assurance Project Plan (Qapp) (Dated June 1, 2026), Emma Rott Jun 2026

Re: Conditional Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Clark Tailings Consolidated Waste Management Area (Ctcwma) Site Investigation Quality Assurance Project Plan (Qapp) (Dated June 1, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Where Evidence-Based Medicine Meets Ai: Promise, Pitfalls, And Practice, Sangil Lee, Joshua Davis, Ken Milne, Christina Shenvi, Lars K. Beattie, Martin Wegman, Laura Melville, Richard D. Shih, Bryan Kane Jun 2026

Where Evidence-Based Medicine Meets Ai: Promise, Pitfalls, And Practice, Sangil Lee, Joshua Davis, Ken Milne, Christina Shenvi, Lars K. Beattie, Martin Wegman, Laura Melville, Richard D. Shih, Bryan Kane

Department of Emergency Medicine Faculty Papers

No abstract provided.


Integration Of Intraoperative Data In Interpretable Machine Learning Models To Predict Postoperative Aki In Noncardiac Surgery Patients, Justin Do, Karan H. Shah, Melissa Xu, Andrew Hyunwoo Kim, Vivaswat Suresh, Nidhir Guggilla, Michael Li, Rishi Kothari Jun 2026

Integration Of Intraoperative Data In Interpretable Machine Learning Models To Predict Postoperative Aki In Noncardiac Surgery Patients, Justin Do, Karan H. Shah, Melissa Xu, Andrew Hyunwoo Kim, Vivaswat Suresh, Nidhir Guggilla, Michael Li, Rishi Kothari

Department of Anesthesiology Faculty Papers

OBJECTIVES: We aimed to (1) quantify changes in discrimination when adding intraoperative data to preoperative data and (2) compare tabular machine learning with feature engineering against a time-aware LSTM-based model.

MATERIALS AND METHODS: Retrospective cohort of 46 204 adults undergoing 57 055 eligible noncardiac surgery in the INSPIRE database. We extracted 38 preoperative and 49 intraoperative variables; acute kidney injury (AKI) was defined by KDIGO serum creatinine criteria and modeled as stage 2/3 postoperative AKI. Models were trained on preoperative-only and combined pre- and intraoperative data. Intraoperative series were summarized using eight statistical features for tabular models or integrated directly …


Artificial Intelligence Empowers Particle Physics And Nuclear Physics: From Fundamental Research To Major Applications, Yifang Wang, Yuan He, Yao Huang, Wanbing He, Yi Jiao, Congqiao Li, Ke Li, Beijiang Liu, Yingqi Ma, Yugang Ma, Longgang Pang, Fazhi Qi, Sichao Tan, Chunpeng Wang, Meng Wang, Xiaoheng Xu, Xing Xu, Zhentang Zhao, Yingxun Zhang, Zhengde Zhang, Hongwei Zhao, Lina Zhao Jun 2026

Artificial Intelligence Empowers Particle Physics And Nuclear Physics: From Fundamental Research To Major Applications, Yifang Wang, Yuan He, Yao Huang, Wanbing He, Yi Jiao, Congqiao Li, Ke Li, Beijiang Liu, Yingqi Ma, Yugang Ma, Longgang Pang, Fazhi Qi, Sichao Tan, Chunpeng Wang, Meng Wang, Xiaoheng Xu, Xing Xu, Zhentang Zhao, Yingxun Zhang, Zhengde Zhang, Hongwei Zhao, Lina Zhao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Particle physics and nuclear physics are core foundational disciplines for exploring the fundamental structure of matter and the origin of the universe. The deep integration of artificial intelligence (AI) technology is providing entirely new pathways to address systemic challenges such as the processing of massive amounts of multimodal data, the realization of extreme experimental conditions, bottlenecks in theoretical calculations, and the intelligent control of large-scale scientific facilities. The article systematically elaborates on how AI deeply empowers particle physics and nuclear physics, particularly in major application scenarios such as research on the fundamental structure and origin of mass of matter, the …


Consolidating Chemical Substance Creation Capability Through Ai For Science-Enabled Innovation Equity, Mengchu Jin, Wandong Wang, Jun Zhang, Yi Luo, Zaiku Xie, Jinlong Yang, Jun Jiang Jun 2026

Consolidating Chemical Substance Creation Capability Through Ai For Science-Enabled Innovation Equity, Mengchu Jin, Wandong Wang, Jun Zhang, Yi Luo, Zaiku Xie, Jinlong Yang, Jun Jiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

AI for Science (hereinafter referred to as AI4S) is driving profound changes in the paradigm of scientific research. Chemistry, as a central discipline for creating new substances and supporting major national strategic needs such as energy, health, dual carbon goals, advanced manufacturing, and ecological governance, is an important application scenario of AI4S. At present, innovation in the discipline of chemistry by young researchers still faces knowledge silos, capability silos, and resource silos: the accumulation of professional knowledge requires years of effort, frontier knowledge is highly differentiated, experimental capabilities are difficult to reuse, and high-end resources are difficult to coordinate, which …


Artificial Intelligence Empowered Biological Research: Paradigm Shifts, Application Scenarios, And Strategic Layout, Xinguang Zhu, Yiming Bao, Zhenong Jin, Xin Li, Sijia Wang, Yueming Wang, Yungui Yang, Cao Xu, Yan Xiong, Bin Han Jun 2026

Artificial Intelligence Empowered Biological Research: Paradigm Shifts, Application Scenarios, And Strategic Layout, Xinguang Zhu, Yiming Bao, Zhenong Jin, Xin Li, Sijia Wang, Yueming Wang, Yungui Yang, Cao Xu, Yan Xiong, Bin Han

Bulletin of Chinese Academy of Sciences (Chinese Version)

Life related processes are characterized by high dimensionality and multi-scale properties. Understanding mechanisms underpinning life processes helps promote national healthcare, agricultural development, sustainable ecological civilization, and national security. Current life science research is confronted with an enormous challenge of dimensionality stemming from data explosion and data fragmentation, for which the recent rapid advancement of artificial intelligence (AI) provides novel solutions. AI will catalyze a paradigm shift in life science research from the current experiment based empirical induction to a new closed-loop knowledge acquisition including large scale data collection, model building, model prediction, experimental validation, and iterative of these procedures. Life …


Artificial Intelligence–Driven Paradigm Transformation In Biopharmaceutical R&D: Applications And Emerging Scenarios, Lili Liu, Mingyue Zheng, Ye Yuan, Xutong Li, Rong Fan, Wei Wei, Jinxin Zhao, Guobin Qi, Hua Yue, Likun Gong, Songping Zhang, Jiachen Li, Yuchen Sun, Xiaoyan Chen, Yao Chen, Xin Liu, Xiao Zhang, Yuehong Gao, Jianfeng Li, Kaixian Chen, Guanghui Ma, Jianmin Yue Jun 2026

Artificial Intelligence–Driven Paradigm Transformation In Biopharmaceutical R&D: Applications And Emerging Scenarios, Lili Liu, Mingyue Zheng, Ye Yuan, Xutong Li, Rong Fan, Wei Wei, Jinxin Zhao, Guobin Qi, Hua Yue, Likun Gong, Songping Zhang, Jiachen Li, Yuchen Sun, Xiaoyan Chen, Yao Chen, Xin Liu, Xiao Zhang, Yuehong Gao, Jianfeng Li, Kaixian Chen, Guanghui Ma, Jianmin Yue

Bulletin of Chinese Academy of Sciences (Chinese Version)

The biopharmaceutical industry is a critical domain underpinning national scientific and technological innovation development and public health. With the rapid advancement of artificial intelligence (AI) and its deep integration with the life sciences, biomedicine research is undergoing a paradigm shift from traditional experience-driven trial-and-error approaches to data-driven and predictive validation-based models. This study systematically examines the pathways for reshaping research in biomedicine paradigms under the convergence of data-driven, mechanism-driven, and intelligence-driven approaches. It focuses on recent advances in the application of AI across key stages, including drug discovery and design, druggability evaluation, delivery system design and optimization, nonclinical and clinical …


Artificial Intelligence Empowering Space Science—Case Study Of Space Weather, Chi Wang, Hui Li, Bingxian Luo, Fang Shen, Jingjing Wang, Lingqian Zhang, Yi Yang, Dong Zhao Jun 2026

Artificial Intelligence Empowering Space Science—Case Study Of Space Weather, Chi Wang, Hui Li, Bingxian Luo, Fang Shen, Jingjing Wang, Lingqian Zhang, Yi Yang, Dong Zhao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Space science is currently confronted with a triple challenge: the explosive growth of observational data, the strongly coupled cross-scale nature of physical processes, and the increasingly urgent national strategic demands. The limitations of traditional research paradigms in analytical efficiency, forecast accuracy, and autonomous capability hinder their effectiveness in meeting critical requirements such as safeguarding on-orbit satellites and ensuring the successful execution of major space missions. This study proposes a three-layer “perception–cognition–decision-making” architecture for intelligent space science. Taking space weather—a domain with strong operational relevance—as a representative case, the four-dimensional paradigm transformation driven by artificial intelligence is systematically examined across key …


Relay Selection And User Scheduling In Reconfigurable Intelligent Surface Assisted Millimeter-Wave D2d Communication, Lakshmikanta Sau Jun 2026

Relay Selection And User Scheduling In Reconfigurable Intelligent Surface Assisted Millimeter-Wave D2d Communication, Lakshmikanta Sau

Doctoral Theses

Reconfigurable intelligent surface (RIS) assisted millimeter wave (mmWave) device to device (D2D) communication has recently been proposed as a viable solution to support the overwhelming data traffic in fifth-generation (5G) and beyond wireless networks. However, due to the substantial propagation and penetration losses of mmWave, a direct line of sight (LoS) link between a pair of proximity devices is required for effective communication. Static obstacles like trees and buildings can easily obstruct the direct LoS connectivity between a device pair. In such cases, RISs help to establish an indirect LoS link between an obstructed device pair by reflecting the signals …


The Ecotoxicological Implications Of Switching From Fluorescent To Light Emitting Diode Lighting For Zooplankton Culturing And Whole Effluent Toxicity Testing, Orithea Z. Regn Jun 2026

The Ecotoxicological Implications Of Switching From Fluorescent To Light Emitting Diode Lighting For Zooplankton Culturing And Whole Effluent Toxicity Testing, Orithea Z. Regn

Student Theses and Dissertations

In the global transition toward light emitting diode (LED) lighting, an understudied area is the impact on the culturing and testing of Whole Effluent Toxicity (WET) testing organisms, more specifically, the zooplankton species. Without comparison to the current lighting used for culturing and testing, it is unknown if there will be an impact on performance, which could affect effluent, regulatory, and product safety decisions. This dissertation investigated if culturing and reference toxicity testing using sodium chloride for Ceriodaphnia dubia, Daphnia magna, and D. pulex under LED lighting was comparable to fluorescent. Comparisons were made between two laboratories and by season, …


Knowledge, Attitude, And Practice Regarding Vitamin D Among Adults In Western Libya: Assessment And Socio-Demographic Influences, Abdounasser Albasher Omar, Kawther Adaila, Mofida M. Alfaid, Abdurrahman M Sweidan, Ruqayah Kasheem, Samia Emhemmed Abadi, Abdulnabi Ali Abushita, Hafsa A. Alemam Jun 2026

Knowledge, Attitude, And Practice Regarding Vitamin D Among Adults In Western Libya: Assessment And Socio-Demographic Influences, Abdounasser Albasher Omar, Kawther Adaila, Mofida M. Alfaid, Abdurrahman M Sweidan, Ruqayah Kasheem, Samia Emhemmed Abadi, Abdulnabi Ali Abushita, Hafsa A. Alemam

Al-Bahir

Vitamin D deficiency is a widespread public health concern, necessitating a clear understanding of knowledge, attitudes, and practices (KAP) among populations. Therefore, this study was conducted to assess Libyan citizens' knowledge, attitude, and practice (KAP) regarding vitamin D in the western region of Libya. This study was carried out between June and September of 2021. A questionnaire was distributed across the study area and the complete responses were 314, with 62.7% were females and 37.3% were males.  The scores were calculated as percentages and statistically tested. Additionally, the impact of some socio-demographic factors (age, gender, education level, job, and salary) …


Alcohol-Based Microextraction Of Rhodamine 6g From Soft Drink, Food, And Cosmetic Samples, Mustafa Soylak, Esra Yamaner, Özgür Özalp Jun 2026

Alcohol-Based Microextraction Of Rhodamine 6g From Soft Drink, Food, And Cosmetic Samples, Mustafa Soylak, Esra Yamaner, Özgür Özalp

Turkish Journal of Chemistry

By using alcohol-based solvent extraction without tetrahydrofuran, a liquid–liquid microextraction technique was developed for the separation–enrichment of trace levels of Rhodamine 6G from complex matrices, including soft drinks, food, cosmetics, hygiene products, and natural waters. Numerous experimental parameters were tuned, including pH, alcohol volume, ultrasonication time, and sample and eluent volume. The enrichment factor (EF), limit of detection (LOD), and limit of quantification (LOQ) were used to assess the analytical performance of the suggested approach. The LOD and LOQ were 6.92 ng mL−1 and 23 ng mL−1, respectively, and the EF was 14. Through the use of the standard addition …


Production, Purification, And Crystallization Of The Recombinant Her2 Tyrosine Kinase Domain (Her2-Tkd), Edanur Topalan, Hali̇li̇brahi̇m Çi̇ftçi̇, Hasan Demi̇rci̇ Jun 2026

Production, Purification, And Crystallization Of The Recombinant Her2 Tyrosine Kinase Domain (Her2-Tkd), Edanur Topalan, Hali̇li̇brahi̇m Çi̇ftçi̇, Hasan Demi̇rci̇

Turkish Journal of Chemistry

The human epidermal growth factor receptor 2 tyrosine kinase domain (HER2-TKD) is an important therapeutic target in oncology. In this study, we developed a practical and cost-effective approach for producing soluble recombinant HER2-TKD in Escherichia coli as a basis for structure-based drug discovery. The gene encoding HER2-TKD was cloned into a pET28a(+) expression vector and expressed in E. coli. Since the protein was initially obtained as inclusion bodies, solubilization with 1.5% sarcosyl was applied to recover it in soluble form. The purified protein was obtained through size-exclusion chromatography, followed by tag removal using reverse affinity purification. Crystallization trials were performed …


Quantum Engineered Mxene–Graphene–Plasmonic Nanocomposites For Next-Generation Transparent And Flexible Space Photovoltaics, Arash Vaghef-Koodehi Jun 2026

Quantum Engineered Mxene–Graphene–Plasmonic Nanocomposites For Next-Generation Transparent And Flexible Space Photovoltaics, Arash Vaghef-Koodehi

Turkish Journal of Chemistry

This study presents a quantum‑engineered, tricomponent heterostructure comprising Ti3C2T MXene quantum dots (2–5 nm), single‑layer graphene, and plasmonic gold nanoparticles (15 ± 3 nm) uniformly embedded within electrospun polyacrylonitrile nanofibers. This integrated architecture demonstrates a remarkable combination of optical transparency (89.3 ± 1.1%) and power conversion efficiency (19.7 ± 0.4%) under AM0 solar illumination, representing 340% enhancement over state‑of‑the‑art transparent photovoltaic devices. A multiscale computational framework, bridging density functional theory and device‑level drift-diffusion modeling, identifies optimal interlayer spacing (3.4 ± 0.1 Å) as the key to achieving 89.3% charge‑transfer efficiency. Concurrently, localized surface plasmon resonances at 532 nm generate electromagnetic …