Digital Commons Network^™

Hypergraph Association With Lie Algebra Of Upper Triangular Matrices And Its Application To Wireless Networks, Supriya S

Theses and Dissertations

A hypergraph is a generalized graph characterized by edges spanning more than one vertices describing multiple relationships among them. It provides a mathematical framework for comprehending and learning about a wide range of real-world challenges. On the other side, the theory of non-associative algebras, such as Jordan, Octonions, Malcev, and Lie, has found significant impetus in recent years. These structures proved intriguing from an algebraic standpoint; they generated novel concepts and approaches that aided in solving specific classic algebraic problems, also progressing towards application.

A preeminent observation that galvanizes this thesis is that hypergraph association is still unexplored in Lie …

Stochastic Games Of Parental Vaccination Decision Making And Bounded Rationality, Andras Balogh, Tamer Oraby

School of Mathematical & Statistical Sciences Faculty Publications

Vaccination is an effective strategy to prevent the spread of diseases. However, hesitancy and rejection of vaccines, particularly in childhood immunizations, pose challenges to vaccination efforts. In that case, according to rational decision-making and classical utility theory, parents weigh the costs of vaccination against the costs of not vaccinating their children. Social norms influence these parental decision-making outcomes, deviating their decisions from rationality. Additionally, variability in values of utilities stemming from stochasticity in parents' perceptions over time can lead to further deviations from rationality. In this paper, we employ independent white noises to represent stochastic fluctuations in parental perceptions of …

The Integrated Monitoring Of Karst Systems (Miks) Model, Applied In Karst Studies In Bulgaria, Petar Stefanov, Dilyana Stefanova, Peter Nojarov

International Journal of Speleology

Karst is a widespread natural phenomenon that is highly sensitive and very vulnerable to both natural and various anthropogenic impacts. This is due to the complex structure of karst territories, which comprise both surface forms and complex systems of underground cavities. Therefore, the study of karst requires a geosystem approach and integrated monitoring, which gives a real idea of the state of karst geosystems and the impacts of global changes on karstogenesis. The article presents a model of this approach, which is applied in karst studies in Bulgaria. The methodological basis is the original ProKARSTerra paradigm, based on the geosystem …

Comparing In-Person, Standard Telehealth, And Remote Musculoskeletal Examination With A Novel Augmented Reality Exercise Game System: Pilot Cross-Sectional Comparison Study, Richard Wu, Keerthana Chakka, Sara Belko, Ninad Khargonkar, Kevin Desai, Balakrishnan Prabhakaran, Thiru Annaswamy

SKMC Student Presentations and Publications

BACKGROUND: Current telemedicine technologies are not fully optimized for conducting physical examinations. The Virtual Remote Tele-Physical Examination (VIRTEPEX) system, a novel proprietary technology platform using a Microsoft Kinect-based augmented reality game system to track motion and estimate force, has the potential to assist with conducting asynchronous, remote musculoskeletal examinations.

OBJECTIVE: This pilot study evaluated the feasibility of the VIRTEPEX system as a supplement to telehealth musculoskeletal strength assessments.

METHODS: In this cross-sectional pilot study, 12 study participants with upper extremity pain and/or weakness underwent strength evaluations for four upper extremity movements using in-person, telehealth, VIRTEPEX, and composite (telehealth plus VIRTEPEX) …

Classification Of Schizophrenia, Bipolar Disorder And Major Depressive Disorder With Comorbid Traits And Deep Learning Algorithms, Xiangning Chen, Yimei Lu, Joan Manuel Cue, Mira V Han, Vishwajit L Nimgaonkar, Daniel R Weinberger, Shizhong Han, Zhongming Zhao, Jingchun Chen

Faculty, Staff and Student Publications

Many psychiatric disorders share genetic liabilities, but whether these shared liabilities can be utilized to classify and differentiate psychiatric disorders remains unclear. In this study, we use polygenic risk scores (PRSs) of 42 traits comorbid with schizophrenia (SCZ), bipolar disorder (BIP), and major depressive disorder (MDD) to evaluate their utilities. We found that combining target specific PRS with PRSs of comorbid traits can improve the classification of the target disorders. Importantly, without inclusion of PRSs from targeted disorders, we can still classify SCZ (accuracy 0.710 ± 0.008, AUC 0.789 ± 0.011), BIP (accuracy 0.782 ± 0.006, AUC 0.852 ± 0.004), …

A Review Of Artificial Intelligence, Algorithms, And Robots Through The Lens Of Stakeholder Theory, Michael J. Matthews, Su Runkun, Lindsey Yonish, Shawn Mcclean, Joel Koopman, Kai Chi Yam

Management Faculty Publications

With the arrival of the Fourth Industrial Revolution, intelligent machines are affecting the daily lives of multiple organizational stakeholders. However, despite the continued expansion of intelligent machines in society, management scholarship has generally lagged, and current frameworks are under-equipped to offer meaningful guidance regarding the intersection of intelligent machines and organizations. We address this issue via a multidisciplinary review and a novel framework of intelligent machines and value creation. First, we discuss the characteristics of intelligent machines (i.e., autonomy, learning, inscrutability, and materiality) and how variation in these characteristics impacts their affordances and, subsequently, the value offered to stakeholders. We …

Discovery And Functional Characterization Of Biomarkers In Clear Cell Renal Cell Carcinoma, Wagma Caravan

Arts & Sciences Graduate Student Theses and Dissertations

Not all tumors are created equally, nor should they be treated as such. Modern research has uncovered a multitude of genetic aberrations, genomic dysregulation, and epigenetic modifications that contribute to cancer. While cancers are classified based on their tissue of origin and may share common features or pathways, the tumor microenvironment is far from uniform. It comprises a dynamic network of cell populations with divergent genomic profiles, all of which collectively drive tumor progression—with some tumors more efficient and aggressive than others. The heterogeneity within these tumors makes it notoriously harder to treat, as standard therapies fail to address the …

Optimized Hiv/Aids Resource Allocation In Ohio: A Linear Programming Approach, Godfred Ahenkroa Kesse

Data Science and Data Mining

This study employs a linear and integer programming approach to optimize HIV resource allocation in Ohio, aiming to minimize new infections and enhance the impact of limited resources. With the advances in HIV prevention and treatment, Ohio faces challenges in addressing disparities in access to healthcare, particularly among high-risk populations. The proposed model integrates data on infection rates, transmission patterns, demographic factors, and cost-effectiveness to provide a decision-support framework for policymakers. Using epidemiological data and equity constraints, the model prioritizes high-risk regions and populations while ensuring fair resource distribution. Results indicate that increased funding allocations significantly enhance the potential to …

Impacts Of Changing Temperatures On The Water Budget In The Great Salt Lake Basin, Grace Affram, Jihad Othman, Reza Morovati, Saddy Pineda Castellanos, Sajad Khoshnoodmotlagh, Diana Dunn, Braedon Dority, Katherine Osorio Diaz, Cody Ratterman, Wei Zhang

Plants, Soils and Climate Student Research

Quantifying the water budget in the Great Salt Lake (GSL) basin is a nontrivial task, especially under a changing climate that contributes to increasing temperatures and a shift towards more rainfall and less snowfall. This study examines the potential impacts of temperature thresholds on the water budget in the GSL, emphasizing the influence on snowmelt, evapotranspiration (ET), and runoff under varying climate warming scenarios. Current hydrological models such as the Variable Infiltration Capacity (VIC) model use a universal temperature threshold to partition snowfall and rainfall across different regions. Previous studies have argued that there is a wide range of thresholds …

Exploring Single Cell Microbial Protein As A Sustainable Fishmeal Alternative In Yellowtail Kingfish (Seriola Lalandi) Diets: Impacts On Health And Gut Microbiome, Luke Pilmer, Lindsey Woolley, Alan Lymbery, Chinh Dam, Abigail Elizur, Md Javed Foysal, Gavin Partridge

Fisheries Research Articles

Background

With the global expansion of aquaculture and the increasing demand for fish meal, identifying appropriate and sustainable alternative protein sources for aquafeeds has become essential. Single-cell protein (SCP), derived from methanotrophic bacteria, presents a promising alternative by converting methane into protein, potentially addressing both the need for alternative protein sources and reducing industrial greenhouse gas emissions. This study aimed to evaluate the effects of different levels of SCP inclusion (0%, 25%, 50%, and 75% fish meal replacement) on the health, gene expression, and gut microbiome of yellowtail kingfish (YTK, Seriola lalandi) following a 35-day growth trial.

Results

The …

Icipe Monthly Digest – Volume 1, Issue 2, February 2025, International Centre Of Insect Physiology And Ecology (Icipe)

icipe Newsletters

No abstract provided.

Operationalizing And Measuring Climate Change Adaptation Success, Henry A. Bartelet, Michele L. Barnes, Lalu A.A. Bakti, Graeme S. Cumming

Quantitative Methods and Information Technology Faculty Publications

In a context of rapid global change, understanding whether and how adaptation to climate change can be considered successful has become an important research gap within the climate change adaptation literature. Although definitions of adaptation success have been formulated, it remains unclear how they can be operationalized and tested empirically. To address this gap, we operationalized one of the most prominent definitions of successful adaptation within the academic literature, which describes success as adaptations that support reductions in risk and vulnerability without compromising sustainability. Specifically, drawing on data collected from 209 coral reef tourism operators across 28 locations and eight …

Confronting Catastrophic Risk: The International Obligation To Regulate Artificial Intelligence, Bryan Druzin, Anatole Boute, Michael Ramsden

Michigan Journal of International Law

While artificial intelligence (“AI”) holds enormous promise, many experts in the field are warning that there is a non-trivial chance that the development of AI poses an existential threat to humanity. Existing regulatory initiatives do not address this threat but instead merely focus on discrete AI-related risks such as consumer safety, cybersecurity, data protection, and privacy. In the absence of regulatory action to address the possible risk of human extinction by AI, the question arises: What obligations, if any, does public international law impose on states to regulate its development?

At present there is no scientific consensus as to the …

Environmental Monitoring Report: For Work To Be Performed: July 1, 2023 Through June 30, 2024, Tennessee. Department Of Environment And Conservation

Environmental Monitoring Reports

This FY2024 EMR presents results for independent projects, originally defined in TDEC’s FY2024 Environmental Monitoring Plan (EMP) and subsequently completed over the course of FY2024 period of performance.

Zombie-Auras: Genai And Hybrid Text Production, Joshua Nieubuurt

English Faculty Publications

This paper explores the iterative evolutions of textual production and their impact on the “aura” of texts, as conceptualized by Walter Benjamin. The study identifies three key phases of textual production: the natural, the mechanized, and the digitized, each progressively displacing the “cult value” of texts. This cult value is lost through increased ease of creation, reproduction, dissemination, and dislocation of creators and audiences in time and space. The advent of Generative AI (GenAI) marks the latest evolution, transforming the “aura” into a memetic “zombie” form—familiar yet opaque, evoking both the sublime and fear. By examining Benjamin’s notion of “aura” …

The Role Of Secondary And Tertiary Structure In The Cap-Independent Translation Of Fgf-9 And Hif-1-Alpha, Amanda Michelle Whittaker

Dissertations, Theses, and Capstone Projects

Under normoxic conditions, eukaryotes initiate translation of RNA through eIF4E recognition of the 5’ cap. However, under cellular stress, eukaryotic translation must be initiated through a 4E-independent, or “cap-independent” mechanism, involving eukaryotic initiation factor 4G (eIF4G) binding directly to the 5’ untranslated regions (5’ UTR) of the RNA. eIF4G binding then recruits the ribosome to the transcript. While this mechanism is useful for translation of apoptotic transcripts and transcripts involved in cell survival, cap-independent translation is also utilized by oncogenic RNA for tumorigenesis. Previous work by our lab and others has categorized this recruitment and initiation mechanism as either internal-ribosome-entry-site …

Studies On The Synthesis, Function, And Properties Of Troponoids, John-Charles A. Baucom

Dissertations, Theses, and Capstone Projects

Troponoids are a unique class of non-benzenoid aromatic compounds with a wide range of demonstrated applications in pharmaceuticals and molecular sensing. The cycloheptatrienone scaffold possesses a noteworthy degree of tunability as a function of ring oxygenation. This manuscript describes our efforts toward a better understanding of the physical consequences of the scaffold to better utilize the motif. Chapter the first discusses our efforts at elucidating the mechanism of troponoid inhibition of the Hepatitis B virus reverse transcriptase RNAse H enzymatic domain. Using homology modeling in conjunction with traditional in vitro assays we were able to establish the likely mechanism of …

Tracing The Sources Of Nitrogen In Submarine Groundwater Discharge And Primary Producers In The Great South Bay Estuary, Nia H. Rene

Dissertations, Theses, and Capstone Projects

The primary aim of this research was to elucidate the impact of submarine groundwater discharge (SGD) and septic effluent on coastal primary producers in the Great South Bay (GSB). The study focused on three main objectives: assessing the impact of precipitation patterns on SGD, tracing nitrogen sources into the GSB, and determining the impact of these nitrogen sources on coastal primary producers. The research revealed that current precipitation patterns significantly influence SGD across different seasons, highlighting the seasonal variability in groundwater discharge and its implications for nutrient loading in coastal waters. A suite of tracers was employed to identify and …

Taming Biological Complexity Through The Use Of Symmetries, Luis A. Álvarez-García

Dissertations, Theses, and Capstone Projects

The study of biological systems is, inherently, the study of very complex systems. This is essentially due to the fact that they are made up of numerous, often very complicated, interactions between an extensive number of components. Often necessitating an abundance of quantitative parameters and details for a precise description. The human brain for ex- ample, consisting of ∼ 80 billion neurons with ∼ 800 to 100 trillion connections between them, each of them depending on a large set of parameters. Even simpler examples such as bacterial organisms, such as E. coli and B. subtilis, which we focus on …

Development Of Soil Survey Methods For Urban Areas, Kohinoor Begum

Dissertations, Theses, and Capstone Projects

Urban soils are the foundation of urban ecosystems and play a vital role in long-term urban sustainability and resiliency. Accurate soil surveys of urban areas should be done at higher resolution since extensive human activities often result in urban soil being highly disturbed and spatially variable. Besides heterogeneity, one of the unique and challenging aspects of urban soil is the nature and properties of its organic carbon with a significant percentage of black carbon (a particulate product of incomplete combustion), which is less biologically active. Thus, in order to determine the ability of a soil to support biological activity and …

Novel Alchemical Methodologies For Modeling Molecular Binding, Solmaz Azimi

Dissertations, Theses, and Capstone Projects

Molecular recognition is fundamental to all biological and biochemical processes. Understanding the interactions between molecules is the foundation for drug discovery and development, for understanding biological processes, and for the design of biosensors and nanomaterials. There is tremendous interest in the development of computer models to predict molecular association equilibria. In structure-based drug discovery enterprises, predicting the strength and selectivity of a small molecule to a biological target can advance target identification, aid ligand design, and accelerate high-throughput screening of drug compounds. This work focuses on free energy models, a class of computational methodologies grounded on the fundamental physical and …

Quantified Lives: Data, Bias, And The Cost Of Categorization, Colin F. Geraghty

Dissertations, Theses, and Capstone Projects

This project critically examines how statistical methods and data visualization have historically been used to categorize, rank, and control human populations. By exploring the works of key figures like Francis Galton, Karl Pearson, and R.A. Fisher, it traces the evolution of categorization frameworks from their eugenic roots to modern applications in artificial intelligence and global metrics like the World Happiness Report. Through interactive visualizations and historical analysis, the project invites users to question the legitimacy of these frameworks and reflect on their impact on society. At its core, this work emphasizes the need to move beyond rigid classification systems, challenging …

Draft Final Bpsou Insufficiently Reclaimed Sites Josephine Shaft (Ir-37) Remedial Action Work Plan (Rawp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Assessing Vegetation Changes And Ecosystem Impacts Of Invasive Species In Florida's Water Conservation Area 3a (2004–2024) Using Landsat Data, Gideon Tandoh

Research, Papers & Creative Work

The spread of invasive species is a concrete problem, threatening biodiversity, ecosystem integrity, and the functional status of wetlands. As these species continue to advance, it is crucial to assess their spread as well as management success through the more sophisticated invasive monitoring methodologies. This research examines the change in vegetation communities and the spread of invasive plants in the Water Conservation Area 3A (WCA-3A) using Object-Based Image Analysis (OBIA) and Support Vector Machine (SVM) classifiers on time series Landsat images. Unlike traditional pixel-based methods, OBIA enhances classification accuracy by incorporating spatial, spectral, and contextual information, enabling precise differentiation between …

Analysis Of 26 Studies Of The Impact Of Coconut Oil On Lipid Parameters: Beyond Total And Ldl Cholesterol, Mary T. Newport, Fabian M. Dayrit

Chemistry Faculty Publications

Coconut oil (CNO) is often characterized as an “artery-clogging fat” because it is a predominantly saturated fat that ostensibly raises total cholesterol (TChol) and LDL cholesterol (LDL-C). Whereas previous analyses assessed CNO based on the relative effects on lipid parameters against other fats and oils, this analysis focuses on the effects of CNO itself. Here, we review the literature on CNO and analyze 984 lipid profile data sets from 26 CNO studies conducted over the past 40 years. This analysis shows considerable heterogeneity among CNO studies regarding participant selection, the amount consumed, and the study duration. The analysis reveals that, …

Project Title: Maximizing The Volume Of A Cardboard Box To Save Trees– An Application Of Polynomial Functions To Address Global Issues [Mathematics], Lucie Mingla

Open Educational Resources

MAT 115 College Algebra & Trigonometry/Precalculus

Project Title: Maximizing the Volume of a Cardboard Box to Save Trees– An Application of Polynomial Functions to Address Global Issues

Reflective Narrative:

This project was inspired by my participation in the "Designing and Implementation of STEM Co-Curricular Activities" CTL seminar in Spring 2023. I am grateful to Drs. Bukurie Gjoci, Daniel Gertner, Ingrid Veras, and Midas Tsai, along with fellow participants, for their invaluable feedback that helped shape its development. The project was implemented in two College Algebra and Trigonometry courses. I participated in two seminars to further develop this project. The Community …

Solvation Thermodynamic Mapping Approaches For Computer-Aided Drug Discovery, Vjay Molino

Dissertations, Theses, and Capstone Projects

The drug discovery process is inherently long and costly, prompting the development and integration of computational tools to mitigate these challenges. One of area explored in computer-aided drug discovery is to understand the role of solvation in protein-drug binding and to develop computational tools and methods that can be integrated in the drug discovery process. Grid Inhomogeneous Solvation Theory (GIST) is a tool that provides a framework for mapping solvation thermodynamiproperties of water molecules on the protein surface.This thesis explores the use of GIST in generating pharmacophore models and elucidates the role of solvation in protein structural fluctuations.

One of …

The Role Of Confined Hydration And Water Reorganization In Molecular Binding, Joe Z. Wu

Dissertations, Theses, and Capstone Projects

An important factor in guiding the development of drug discovery efforts is the comprehensive assessment of a ligand or drug’s ability to bind its receptor. The metric used to measure this interaction strength is by calculating the binding free energy (BFE). To achieve this accurately, we combine two concepts: (1) Grid Inhomogeneous Solvation Theory (GIST) returns the local water thermodynamic and structural contributions to free energy; and the (2) Alchemical Transfer Method (ATM) obtains the absolute (ABFE) and relative binding free energy (RBFE) estimates between ligand pairs. In this work, we employ Alchemical Water-Transfer to tether bridging water(s) during the …

Effectiveness Of Postoperative Cephalosporins In Reducing Urinary Tract Infections And Other Parameters Following Transurethral Resection Of The Prostate: A Systematic Review And Meta-Analysis, Wael Hafez, Feras Al-Obeidat, Asrar Rashid, Arun Kumar Venkatachalapathi, Amr Massaod, Ziad Albaha, Samy Kishk, Tesfalidet Emoshe, Samuel Tesfaye Tefera, Ismail A. Ibrahim, Mohammad Alkammar, Gowhar Rashid, Ahmed Fayed, Karim Soliman, Abdulqadir J. Nashwan, Alaaldeen Mohamed, Daniel Simancas-Racines, Ivan Cherrez-Ojeda

All Works

No abstract provided.

Childhood Sexual Trauma, Substance Use, And Antiretroviral Therapy Adherence Among Older Adults Living With Hiv: A Mediational Analysis, Monique J. Brown, Josie Zhang, Prince Nii Ossah Addo, Amandeep Kaur, Daniel Amoatika, Elizabeth L. Crouch Ph.D., Steven A. Cohen

Faculty Publications

Childhood sexual abuse (CSA) is linked to substance use and lower antiretroviral therapy (ART) adherence. However, studies examining the mediational role of substance use between CSA and ART adherence are lacking. Therefore, the aim of this study was to determine the potential mediational role of substance use between CSA and ART adherence among older adults living with HIV (OALH) (n = 91). Mediation analyses assessed the direct and indirect relationships between CSA, substance use, and ART adherence. Statistically significant differences existed in substance use by gender (male vs. female: 12.3 vs. 9.97) and ART adherence by race (Black vs. …