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Body Mass Index Has No Impact On Complications And Mortality For Patients With Stage Iv Pancreatic Ductal Adenocarcinoma, Ren Bryant, Hannah Darnell, Megan Hall, Kelsey N. Karnik, Kristen J. Mcquerry, Ruben R. Plentz Jan 2026

Body Mass Index Has No Impact On Complications And Mortality For Patients With Stage Iv Pancreatic Ductal Adenocarcinoma, Ren Bryant, Hannah Darnell, Megan Hall, Kelsey N. Karnik, Kristen J. Mcquerry, Ruben R. Plentz

Biostatistics Faculty Publications

Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of United States (USA) cancer death. Overweight and obesity developing into a growing global medical and socio-economic problem, affecting approximately 42% of adults in the USA population. The aim of our analysis was to evaluate the influence of overweight and obesity on complications and clinical outcome in patients with stage IV PDAC.

Methods: We retrospectively reviewed electronic health records of patients diagnosed with stage IV PDAC (n=162) who followed with the University of Kentucky from January 2017–October 2024. Comparisons were based on the body mass index (BMI): low BMI …


Identifying New Programme Development Viability, Grant Goodwin Jan 2026

Identifying New Programme Development Viability, Grant Goodwin

ICT

Higher Education Institutions (HEIs) face the challenge of developing programmes that respond to changing labour market needs while providing graduates with relevant employment opportunities and ensuring institutional financial viability. Rapid technological and economic changes make it increasingly important for HEIs to use reliable data to identify emerging skills and workforce demands. This project explores the use of machine learning and nationally collected employment data to support evidence-based decision-making in higher education programme development. By analysing patterns and relationships within labour market data, machine learning models can help identify areas of growing demand and provide insights into the potential alignment between …


Machine Learning For Early Obesity Risk Prediction, Giuseppe Cutugno Jan 2026

Machine Learning For Early Obesity Risk Prediction, Giuseppe Cutugno

ICT

Obesity is a major global public health concern, with significant implications for individual health, healthcare systems, and wider economic outcomes. Early identification of obesity risk can support preventive strategies and encourage healthier lifestyle choices before health conditions become more severe. This project develops a machine learning framework for estimating obesity levels using data relating to individuals’ physical characteristics, eating habits, lifestyle behaviours, and demographic factors. Following the CRISP-DM framework, the project examines the structure and limitations of the dataset, including its mixture of objective measurements, survey-based variables, and synthetically generated observations. Two modelling approaches are considered, one including BMI as …


Design, Syntheses And Biological Applications Of Fluorescent Probes For Nad(P)H, Hsa And Cellular Microenvironment Sensing, Adenike M. Olowolagba Jan 2026

Design, Syntheses And Biological Applications Of Fluorescent Probes For Nad(P)H, Hsa And Cellular Microenvironment Sensing, Adenike M. Olowolagba

Dissertations, Master's Theses and Master's Reports

Fluorescent probes have emerged as powerful tools for investigating complex biological processes due to their high sensitivity, selectivity, and capability for real-time, non-invasive imaging. In particular, the detection of key biomolecules such as NAD(P)H, viscosity-related parameters, human serum albumin (HSA), and pH is essential for understanding cellular metabolism, redox homeostasis, and disease progression. In Chapter 2, three coumarin-based fluorescent probes (A–C) were designed, synthesized, and characterized for monitoring NAD(P)H levels in living cells. Probes A and B feature coumarin–cyanine hybrid structures linked via vinyl and thiophene bridges to 3-quinolinium acceptors, respectively, while probe C incorporates a dicyano moiety to replace …


Computational And Ai Frameworks For Identifying Key Regulatory Genes And Their Target Genes In Plants And Humans, Md Khairul Islam Jan 2026

Computational And Ai Frameworks For Identifying Key Regulatory Genes And Their Target Genes In Plants And Humans, Md Khairul Islam

Dissertations, Master's Theses and Master's Reports

This dissertation presents computational and AI-driven frameworks for identifying key regulatory genes and their downstream targets across plant and human biological systems. Three studies address distinct challenges in genomic regulation using advanced machine learning and bioinformatics approaches.

The first study introduces DyGAF (Dynamic Gene Attention Focus), a dual-attention transformer framework that identifies and ranks disease-relevant biomarker genes by simultaneously modeling independent molecular responses and interdependent regulatory network behavior. Two attention models provide complementary perspectives on gene importance and are fused through a novel combination metric. Applied to COVID-19 nasopharyngeal swab profiles, the attention-weighted representations achieved 94.23% classification accuracy, high sensitivity, …


Bayesian Analysis Of Nominal Outcomes With Missing Values Using Multinomial And Multivariate Multinomial Probit Models, Suwash Silwal Jan 2026

Bayesian Analysis Of Nominal Outcomes With Missing Values Using Multinomial And Multivariate Multinomial Probit Models, Suwash Silwal

Dissertations, Master's Theses and Master's Reports

Nominal outcomes frequently arise in health sciences, transportation, economics, market research, and related fields. These data often contain missing values, while longitudinal and panel studies generate multiple correlated nominal responses. Bayesian estimation of multinomial probit (MNP) and multivariate multinomial probit (MMNP) models provides a flexible framework for analyzing such data but remains computationally challenging due to high-dimensional likelihood integration, restrictive covariance identification constraints, and poor mixing of Markov chain Monte Carlo (MCMC) algorithms, particularly in the presence of missing data. This dissertation develops parameter-expanded data augmentation (PX-DA) methods for MNP and MMNP models with missing nominal outcomes by incorporating parameter …


Applied Forest Restoration And Conservation In Michigan: Advancing American Beech Restoration And Documenting A Historical Insect Collection, Thomas E. Panella Jan 2026

Applied Forest Restoration And Conservation In Michigan: Advancing American Beech Restoration And Documenting A Historical Insect Collection, Thomas E. Panella

Dissertations, Master's Theses and Master's Reports

Forest restoration and conservation require both practical management approaches and the preservation of biological resources that support future research. This dissertation presents applied research conducted in Michigan that advances American beech (Fagus grandifolia) restoration in response to beech bark disease (BBD) while documenting an important historical entomological resource. Chapters 1–3 focus on overcoming practical barriers to American beech restoration. Restoration protocols were developed and refined for identifying BBD-resistant trees, graft propagation, rootstock collection, container production, and the field establishment of grafted BBD-resistant trees. A greenhouse experiment evaluated the influence of growing media and fertilization on container stock quality, …


Predicting Loneliness Among Older Adults In Ireland Using Supervised Machine Learning, Ariadne Chaves Miranda Jan 2026

Predicting Loneliness Among Older Adults In Ireland Using Supervised Machine Learning, Ariadne Chaves Miranda

ICT

Over the last two decades, technology has grown exponentially and has facilitated communication that helps individuals remain connected. However, this has also contributed to social isolation and lack of physical interaction. One consequence of this phenomenon is loneliness, which is understood as an unpleasant subjective state of discrepancy between the desired amount of companionship or emotional support and what is available in the person’s environment (Prohaska and Burholt, 2020). In the European context, Ireland has emerged as the loneliest country in Europe with 20% of its population that have reported feeling lonely most or all the time (Schnepf et al., …


Designing Narrative-Based Ai Assistance For Sensemaking In Collaborative Environments: Case Studies In Education And Dementia Care, Dylan Edward Moore Jan 2026

Designing Narrative-Based Ai Assistance For Sensemaking In Collaborative Environments: Case Studies In Education And Dementia Care, Dylan Edward Moore

Dartmouth College Ph.D Dissertations

This thesis addresses a gap in the human-computer interaction literature regarding the design, development, and evaluation of narrative-based AI assistance for collaborative, complex problem solving. I explore this design space through three case studies across the domains of education and dementia care. This work encompasses multi-year industry partnerships and longitudinal fieldwork, user-centered design, dataset curation, model training, and system evaluation.

Specifically, the first case study considers a story-based web platform for teaching AI literacy through peer-generated, personalized narrative scaffolding. Learners on the platform showed significant knowledge gains and other learning-related outcomes. To describe the novel design of this system, I …


Dcmm-Transformer: Degree-Corrected Mixed-Membership Attention For Medical Imaging, Huimin Cheng, Xiaowei Yu, Shushan Wu, Luyang Fang, Chao Cao, Jing Zhang, Tianming Liu, Dajiang Zhu, Wenxuan Zhong, Ping Ma Jan 2026

Dcmm-Transformer: Degree-Corrected Mixed-Membership Attention For Medical Imaging, Huimin Cheng, Xiaowei Yu, Shushan Wu, Luyang Fang, Chao Cao, Jing Zhang, Tianming Liu, Dajiang Zhu, Wenxuan Zhong, Ping Ma

Computer Science Faculty Research & Creative Works

Medical images exhibit latent anatomical groupings, such as organs, tissues, and pathological regions, that standard Vision Transformers (ViTs) fail to exploit. While recent work like SBM-Transformer attempts to incorporate such structures through stochastic binary masking, they suffer from non-differentiability, training instability, and the inability to model complex community structure. We present DCMM-Transformer, a novel ViT architecture for medical image analysis that incorporates a Degree-Corrected Mixed-Membership (DCMM) model as an additive bias in self-attention. Unlike prior approaches that rely on multiplicative masking and binary sampling, our method introduces community structure and degree heterogeneity in a fully differentiable and interpretable manner. Comprehensive …


Adversarial Robustness In Biomedical Time-Series Models, Rohan Tiwari Jan 2026

Adversarial Robustness In Biomedical Time-Series Models, Rohan Tiwari

Bioengineering Theses

This study investigates adversarial vulnerabilities in deep learning models for biomedical time-series classification across two clinically important modalities: electrocardiography (ECG) and electroencephalography (EEG). Using the MIT-BIH Arrhythmia and CHB-MIT seizure datasets, I evaluate time-domain attacks (FGSM, PGD), Fourier-domain constrained attacks, and learned spectral perturbations designed to reveal modality-specific sensitivity patterns. Across both tasks, a consistent trend emerges low-frequency components (0–5 Hz) constitute a dominant axis of adversarial vulnerability, with perturbations in this range producing the steepest degradation in classification performance. In ECG models, protecting the physiologically relevant QRS band (5–20 Hz) significantly improves robustness, whereas EEG models remain highly sensitive …


Artificial Intelligence–Enabled Revenue Cycle Management And Financial Performance In Healthcare Organizations, K’Reesa Webster Jan 2026

Artificial Intelligence–Enabled Revenue Cycle Management And Financial Performance In Healthcare Organizations, K’Reesa Webster

Theses, Dissertations and Capstones

The purpose of this review was to examine how artificial intelligence–enabled revenue cycle management (AI-enabled RCM) systems have been associated with financial performance outcomes in healthcare organizations. A literature review following a systematic process consistent with PRISMA 2020 guidelines was conducted to identify quantitative studies published between 2015 and 2026. Eligible studies were required to report at least one financial outcome related to claim denial rate, days in accounts receivable, or operating margin. Twenty-seven studies met all inclusion criteria. Findings across these studies indicated that AI-enabled RCM systems have been associated with lower denial rates, shorter accounts receivable timelines, and …


Distilling The Complexity Of Agent-Based Simulations Into Textual Explanations Via Large Language Models, Noé Y. Flandre, Philippe J. Giabbanelli Jan 2026

Distilling The Complexity Of Agent-Based Simulations Into Textual Explanations Via Large Language Models, Noé Y. Flandre, Philippe J. Giabbanelli

VMASC Publications

Communicating the design and results of agent-based models (ABMs) to subject matter experts is challenging, which hinders participation and limits trust in simulation-based decision support. Large language models (LLMs) can communicate ABMs as textual summaries, thus complementing traditional disclosure through statistical and visualization techniques. While prior work translated the structure of conceptual models into narratives via LLMs, our extension covers the dynamics of simulation models via an automated simulation-to-text method that extracts contextual information from NetLogo ABMs, performs repeated simulations, and generates narrative descriptions (including the model’s purpose, parameters, and simulation dynamics) using mutimodal LLMs. Furthermore, four summarization algorithms spanning …


Federated Data Engineering And Learning For Edge Intelligence Systems, Afsaneh Mahanipour Jan 2026

Federated Data Engineering And Learning For Edge Intelligence Systems, Afsaneh Mahanipour

Theses and Dissertations--Computer Science

The rapid proliferation of Internet of Things (IoT) devices and cyber–physical systems (CPS) in domains such as smart healthcare, intelligent transportation, and industrial automation has led to unprecedented volumes of heterogeneous data. While advances in deep learning and large-scale foundation models have enabled powerful data-driven decision making, their deployment in real-world distributed environments remains fundamentally constrained by limited computation, communication bandwidth, energy resources, and data privacy requirements. This dissertation addresses these challenges by developing novel federated learning frameworks and efficient federated data-processing pipelines that make large-scale artificial intelligence practical, scalable, and trustworthy in resource-constrained settings. This dissertation identifies data preprocessing …


Multi-Objective Optimization Of Energy Costs And Ev Battery Health In V2g Enabled Homes, Dzifa M. Hodey Jan 2026

Multi-Objective Optimization Of Energy Costs And Ev Battery Health In V2g Enabled Homes, Dzifa M. Hodey

Theses and Dissertations--Computer Science

Electric vehicles (EVs) and rooftop solar photovoltaic (PV) systems are increasingly being integrated into residential settings, creating new opportunities for vehicle-to-grid (V2G) and vehicle-to-home (V2H) operations. In these systems, the EV battery functions as a controllable energy storage unit that can charge from the grid or PV and discharge energy to supply household load or export to the grid for a profit. By intelligently scheduling this bidirectional power exchange, households can reduce electricity costs and enhance PV utilization. Realizing these benefits requires optimization strategies that balance cost reduction with EV battery health preservation. However, existing V2G/V2H studies largely emphasize cost …


A Literature Review On Ethics In Medical Diagnostic Ai & Analysis Therein, Connor J. Turetzky Jan 2026

A Literature Review On Ethics In Medical Diagnostic Ai & Analysis Therein, Connor J. Turetzky

Master's Theses

Artificial Intelligence presents a very promising future in medicine. Being able to diagnose and recommend treatments quickly is vital in ensuring positive patient outcomes. However, the new technology is not without risk. In this narrative literature review, the risks of AI in terms of bias, ethics, and environmental impact will be explored through existing research. This paper will focus on research published between 2019 and 2026, highlighting the major ethical and systematic problems currently facing diagnostic AI. Historical bias in medical data has led to AI that share those biases, and humans inherit that bias creating a potential negative feedback …


Differences In Biologic Clinical Trials For Chronic Rhinosinusitis With Nasal Polyps—Are We Comparing Apples With Oranges?, Marjolein Cornet, Peter W. Hellings, Martin Desrosiers, Martin Wagenmann, Richard Follows, Laura Walrave, Luz Adriana Jimenez, Lee Tombs, Dawn Edwards, Peter Howarth, Joseph K. Han Jan 2026

Differences In Biologic Clinical Trials For Chronic Rhinosinusitis With Nasal Polyps—Are We Comparing Apples With Oranges?, Marjolein Cornet, Peter W. Hellings, Martin Desrosiers, Martin Wagenmann, Richard Follows, Laura Walrave, Luz Adriana Jimenez, Lee Tombs, Dawn Edwards, Peter Howarth, Joseph K. Han

Department of Otolaryngology (ENT) Faculty Publications

In recent years, several biologics targeting Type 2 inflammation have been developed for treating chronic rhinosinusitis with nasal polyps (CRSwNP). These have been studied in registrational randomized controlled trials (RCTs), which vary in their patient populations, trial design, endpoints, geography, timing, or data-handling processes. While (in)direct treatment comparisons and meta-analyses have been carried out to compare efficacy results from RCTs, often these fail to properly account for these between-study differences. Here, we summarize the key between-study differences that can influence trial outcomes and highlight the resulting challenges faced when comparing outcomes from different Phase III RCTs of biologics in CRSwNP.


A Comprehensive Survey Of Prompt Engineering Techniques In Large Language Models, Tonmoy Debnath, Md Nurul Absar Siddiky, Muhammad Enayetur Rahman, Prosenjit Das, Antu Kumar Guha, Muhammad Rezaur Rahman, H. M. Dipu Kabir Jan 2026

A Comprehensive Survey Of Prompt Engineering Techniques In Large Language Models, Tonmoy Debnath, Md Nurul Absar Siddiky, Muhammad Enayetur Rahman, Prosenjit Das, Antu Kumar Guha, Muhammad Rezaur Rahman, H. M. Dipu Kabir

Electrical & Computer Engineering Faculty Publications

Prompt engineering has arisen as a pivotal discipline in optimizing the performance of Large Language Models (LLMs) by structuring inputs to enhance coherence, accuracy, and task alignment. This paper comprehensively surveys various prompting techniques, systematically categorizing them according to their application domains and methodological foundations. Fundamental approaches like zero-shot and few-shot prompting are examined along with advanced strategies, including chain-of-thought reasoning, retrieval-augmented generation, and self-consistency mechanisms. A rigorous qualitative analysis is conducted to evaluate each technique's strengths, limitations, and optimal use cases, offering a structured framework for selecting the most effective prompting strategies. Theoretical insights and empirical findings are consolidated …


Physics-Informed Temperature Prediction Of Lithium-Ion Batteries Using Decomposition-Enhanced Lstm And Bilstm Models, Seyed Saeed Madani, Yasmin Shabeer, Michael Fowler, Satyam Panchal, Carlos Ziebert, Hicham Chaoui, François Allard Jan 2026

Physics-Informed Temperature Prediction Of Lithium-Ion Batteries Using Decomposition-Enhanced Lstm And Bilstm Models, Seyed Saeed Madani, Yasmin Shabeer, Michael Fowler, Satyam Panchal, Carlos Ziebert, Hicham Chaoui, François Allard

Electrical & Computer Engineering Faculty Publications

Accurately forecasting the operating temperature of lithium-ion batteries (LIBs) is essential for preventing thermal runaway, extending service life, and ensuring the safe operation of electric vehicles and stationary energy-storage systems. This work introduces a unified, physics-informed, and data-driven temperature-prediction framework that integrates mathematically governed preprocessing, electrothermal decomposition, and sequential deep learning architectures. The methodology systematically applies the governing relations to convert raw temperature measurements into trend, seasonal, and residual components, thereby isolating long-term thermal accumulation, reversible entropy-driven oscillations, and irreversible resistive heating. These physically interpretable signatures serve as structured inputs to machine learning and deep learning models trained on temporally …


Markov Chain Wave Generative Adversarial Network For Bee Bioacoustic Signal Synthesis, Kumudu Samarappuli, Iman Ardekani, Mahsa Mohaghegh, Abdolhossein Sarrafzadeh Jan 2026

Markov Chain Wave Generative Adversarial Network For Bee Bioacoustic Signal Synthesis, Kumudu Samarappuli, Iman Ardekani, Mahsa Mohaghegh, Abdolhossein Sarrafzadeh

Electrical & Computer Engineering Faculty Publications

This paper presents a framework for synthesizing bee bioacoustic signals associated with hive events. While existing approaches like WaveGAN have shown promise in audio generation, they often fail to preserve the subtle temporal and spectral features of bioacoustic signals critical for event-specific classification. The proposed method, MCWaveGAN, extends WaveGAN with a Markov Chain refinement stage, producing synthetic signals that more closely match the distribution of real bioacoustic data. Experimental results show that this method captures signal characteristics more effectively than WaveGAN alone. Furthermore, when integrated into a classifier, synthesized signals improved hive status prediction accuracy. These results highlight the potential …


Mtl_Tx: A Multi-Task Transformer Model For Improved Radiation Time-Series Estimation, Hongfang Zhang, Adam Stavola, Hal Ferguson, Bence Budavari, Hongyi Wu, Chiman Kwan, Jiang Li Jan 2026

Mtl_Tx: A Multi-Task Transformer Model For Improved Radiation Time-Series Estimation, Hongfang Zhang, Adam Stavola, Hal Ferguson, Bence Budavari, Hongyi Wu, Chiman Kwan, Jiang Li

Electrical & Computer Engineering Faculty Publications

Controlling radiation doses at potential radioactive facilities is critical to ensuring the safety of both personnel and the public. At the Thomas Jefferson National Accelerator Facility (JLab), multiple sensors are deployed around the three experimental halls to monitor key parameters, including single-beam current, energy levels, current leakage, and radiation values during accelerator operations. In this study, we developed a Multi-task Transformer model, MTL_TX, to accurately estimate radiation doses at sensor locations based on historical data, with the aim of enhancing safety in accelerator facilities and surrounding public areas. To improve estimation accuracy, we integrated two innovative components into the proposed …


Machine Learning-Based Lifetime Prediction Of Lithium Batteries: A Comparative Assessment For Electric Vehicle Applications, Abdelilah Hammou, Raffaele Petrone, Demba Diallo, Boubekeur Tala-Ighil, Philippe Makany Boussiengue, Hicham Chaoui, Hamid Gualous Jan 2026

Machine Learning-Based Lifetime Prediction Of Lithium Batteries: A Comparative Assessment For Electric Vehicle Applications, Abdelilah Hammou, Raffaele Petrone, Demba Diallo, Boubekeur Tala-Ighil, Philippe Makany Boussiengue, Hicham Chaoui, Hamid Gualous

Electrical & Computer Engineering Faculty Publications

This paper evaluates and compares four data-driven methods (Gaussian Process Regression (GPR), echo state network (ESN), gated recurrent unit (GRU), and long short-term memory (LSTM)) for lithium-ion capacity prognostics adapted to electric vehicle conditions. This comparison aims to find the most efficient prognosis method considering two constraints: the limitation of computational power and the unavailability of on-board capacity measurement that requires full charge and discharge conditions. The machine learning models are trained using capacity values estimated under vehicle conditions. The ageing data is collected from cycling tests of two battery chemistries, Lithium Fer Phosphate (LFP) and Nickel Manganese Cobalt (NMC), …


Digital Twin Technologies For Battery Systems: Advancements, Applications, And Future Directions, Seyed Saeed Madani, Yasmin Shabeer, Michael Fowler, Satyam Panchal, Carlos Ziebert, Hicham Chaoui, François Allard Jan 2026

Digital Twin Technologies For Battery Systems: Advancements, Applications, And Future Directions, Seyed Saeed Madani, Yasmin Shabeer, Michael Fowler, Satyam Panchal, Carlos Ziebert, Hicham Chaoui, François Allard

Electrical & Computer Engineering Faculty Publications

The relationships among deep learning, edge computing, artificial intelligence (AI), and the most recent advancements in digital twin (DT) technology for battery energy storage systems are discussed in this paper. The study highlights the need for improved cloud-edge coordination, AI model development, and stronger cybersecurity features by demonstrating real-world applications of digital twin technology in electric vehicles (EVs), aircraft, and grid storage. It also described DT-based structures for fault detection, real-time monitoring, and optimization through standardization and battery management system (BMS) fusion. Because DT-based solutions for distributed energy resources (DERs) offer improved energy management systems, various studies have been conducted …


Interpretable Battery Soh Prediction: A Comparative Interpretability Framework For Multi-Architecture Ml Models, Shafiyee Islam, Gon Namkoong Jan 2026

Interpretable Battery Soh Prediction: A Comparative Interpretability Framework For Multi-Architecture Ml Models, Shafiyee Islam, Gon Namkoong

Electrical & Computer Engineering Faculty Publications

This work introduces a unified interpretability-efficiency framework for lithium-ion battery state of health (SOH) prediction using hybrid deep learning architectures. We comparatively analyze four hybrid models: CNN LSTM MultiHead, CNN Feature Extractor LSTM, DNN LSTM, and DNN BiLSTM to disentangle how network topology, feature composition, and computational design influence both predictive fidelity and physical interpretability. By integrating Monte Carlo Shapley (MC Shapley), background occlusion SHAP (BoSHAP), and ablation analysis, we quantify the contribution and robustness of five electrochemical feature groups: time, capacity, voltage, dQ/dV and peaks of dQ/dV from NASA battery dataset. The results reveal a consistent dominance of differential …


Standardization Of Neuromuscular Reflex Analysis—Role Of Fine-Tuned Vision-Language Model Consortium And Openai Gpt-Oss Reasoning Llm-Enabled Decision Support System, Eranga Bandara, Ross Gore, Sachin Shetty, Ravi Mukkamala, Christopher K. Rhea, Brittany S. Samulski, Amin Hass, Atmaram Yarlagadda, Shaifali Kaushik, Malith De Silva, Andriy Maznychenko, Inna Sokolowska, Kasun De Zoysa Jan 2026

Standardization Of Neuromuscular Reflex Analysis—Role Of Fine-Tuned Vision-Language Model Consortium And Openai Gpt-Oss Reasoning Llm-Enabled Decision Support System, Eranga Bandara, Ross Gore, Sachin Shetty, Ravi Mukkamala, Christopher K. Rhea, Brittany S. Samulski, Amin Hass, Atmaram Yarlagadda, Shaifali Kaushik, Malith De Silva, Andriy Maznychenko, Inna Sokolowska, Kasun De Zoysa

VMASC Publications

Background/Objectives: Accurate assessment of neuromuscular reflexes, such as the Hoffmann reflex (H-reflex), plays a critical role in sports science, rehabilitation, and clinical neurology. Conventional interpretation of H-reflex electromyography (EMG) waveforms is subject to inter-rater variability and interpretive bias, limiting reliability and standardization. This study aims to develop an automated, interpretable, and robust agentic AI–driven framework for H-reflex waveform analysis. Methods: We propose a fine-tuned Vision–Language Model (VLM) consortium combined with a reasoning Large Language Model (LLM)–enabled decision support system for automated H-reflex interpretation. Multiple VLMs were fine-tuned on curated datasets of H-reflex EMG waveform images annotated with expert clinical observations, …


Machine Learning Classification Of Prostate Cancer Genomic Sequences Using K-Mer And Sequence-Derived Features, Kuldeep Rawat, Hirendra Nath Banerjee, Jamie Noble, Saa Naudia Deloatch, Satyendra Banerjee, Sachin Shetty, Soumya Banerjee Jan 2026

Machine Learning Classification Of Prostate Cancer Genomic Sequences Using K-Mer And Sequence-Derived Features, Kuldeep Rawat, Hirendra Nath Banerjee, Jamie Noble, Saa Naudia Deloatch, Satyendra Banerjee, Sachin Shetty, Soumya Banerjee

VMASC Publications

Prostate cancer disproportionately impacts African American men, who experience significantly higher mortality rates and earlier disease onset than other populations. Current diagnostic approaches, including prostate-specific antigen testing and biopsy, lack sufficient specificity and sensitivity, underscoring the need for accurate, molecular-level classification tools. This paper presents a machine learning framework for binary classification of genomic DNA sequences as cancerous or healthy. A dataset of 1684 FASTA-formatted sequences obtained from the National Library of Medicine - GenBank was analyzed, with 1662 sequences retained after quality control filtering. Feature engineering yielded 67 attributes, including GC content, Shannon entropy, sequence length, and trinucleotide k-mer …


Modeling Rank Distribution And The Relative Importance Factor Index In Discrete Power-Law Models: Application To Social Resilience Using The Scopus Database, Brian Llinas, Jose Padilla, Humberto Llinas, Erika Frydenlund, Katherine Palacio Jan 2026

Modeling Rank Distribution And The Relative Importance Factor Index In Discrete Power-Law Models: Application To Social Resilience Using The Scopus Database, Brian Llinas, Jose Padilla, Humberto Llinas, Erika Frydenlund, Katherine Palacio

VMASC Publications

Prior research on power-law distributions has primarily focused on modeling frequency patterns, with less attention given to rank distributions and how ranked positions reflect relative importance among elements. In discrete power-law distributions, frequency-based metrics often provide limited discrimination in the tail, where elements may exhibit similar counts but differ in relative dominance. These patterns are especially evident, for instance, in academic publishing, where keywords, affiliations, and citations commonly exhibit power-law behavior. To address this limitation, we introduce the Relative Importance Factor (RIF) Index, a statistical measure derived from the estimated discrete power-law rank distribution rather than an additional independent parameter. …


Cybersecurity Center For Offshore Wind Energy (Final Project Round), Sachin Shetty Jan 2026

Cybersecurity Center For Offshore Wind Energy (Final Project Round), Sachin Shetty

Center for Secure and Intelligent Critical Systems (CSICS) Publications

This project establishes a Cybersecurity Center for Offshore Wind Energy with the objective of designing and operating a cyber-physical testbed for wind energy farms (WEFs) that enables comprehensive cybersecurity research. The testbed incorporates a Supervisory Control and Data Acquisition (SCADA) system connected to turbine models via industrial-grade programmable logic controllers (PLCs) and remote terminal units (RTUs). It supports side-channel data acquisition, implementation and analysis of various cyberattack scenarios, and development of attack detection, mitigation, and best-practice guidance tailored to wind energy systems. During the project, the team expanded the number and fidelity of mathematical turbine models (MTMs), integrated these models …


Recent Advances In Triboelectric Nanogenerators For Biomedical And Cardiovascular Monitoring, Amit Sarode, Jegan Rajendran, Gymama Slaughter Jan 2026

Recent Advances In Triboelectric Nanogenerators For Biomedical And Cardiovascular Monitoring, Amit Sarode, Jegan Rajendran, Gymama Slaughter

Center for Bioelectronics Publications

Triboelectric nanogenerators (TENGs) have emerged as versatile self-powered platforms for wearable and implantable biomedical sensing, offering an alternative to battery-dependent electronic devices. By converting biomechanical energy from physiological motion into electrical signals, TENGs enable simultaneous energy harvesting and active sensing within flexible, lightweight, and biocompatible architectures. This review summarizes recent advances from 2020 to 2025 in triboelectric nanogenerator (TENG)-based cardiovascular monitoring. The discussion focuses on material systems, device configurations, sensing mechanisms, and applications including pulse detection and cuffless blood pressure estimation. Representative studies are compared to highlight emerging trends in wearable and self-powered sensing technologies. However, differences in experimental conditions, …


Hydrogeochemical And Redox Controls On Nitrate And Arsenic Co-Occurrence In The Western Kansas High Plains Aquifer (Usa): A Composite Health Risk Assessment And The Case For Risk-Informed Private Well Governance, Jonathan Kuffour Owusu Jan 2026

Hydrogeochemical And Redox Controls On Nitrate And Arsenic Co-Occurrence In The Western Kansas High Plains Aquifer (Usa): A Composite Health Risk Assessment And The Case For Risk-Informed Private Well Governance, Jonathan Kuffour Owusu

Master's Theses or Doctor of Nursing Practice

Fifty-one private domestic wells across western Kansas were sampled to quantify nitrate and arsenic occurrence, identify geochemical controls, and evaluate carcinogenic and non-carcinogenic health risks for adult and child receptors in a region where groundwater serves as the primary drinking water source with no routine regulatory oversight. Samples were analyzed for major ions, nutrients, and trace elements by ICP-MS, ion chromatography, and UV-Vis spectrophotometry. Shapiro-Wilk testing confirmed non-normal distributions for both contaminants; inter-county comparisons were therefore conducted using Kruskal-Wallis tests with Dunn's post-hoc correction. Health risk was quantified via chronic daily intake (CDI), hazard quotient (HQ), HQ-based Water Quality Index …