Digital Commons Network^™

How Is Our Mobility Affected As We Age? Findings From A 934 Users Field Study Of Older Adults Conducted In An Urban Asian City, Yi Zhen Tan, Ngoc Doan Thu Tran, Sapphire Lin, Fang Zhao, Yee Sien Ng, Dong Ma, Jeonggil Ko, Rajesh Krishna Balan

Research Collection School Of Computing and Information Systems

In this paper, we analyze the results of a large study involving 934 older adults living in an urban Asian city that collected their mobility patterns, in the form of logged GPS data, along with a multitude of demographic and health data. We show that mobility, in terms of average distance travelled per day, is greatly affected by age and by employment status. In addition, other factors such as type of day, household size, physical and financial conditions and the onset of retirement also play a significant role in determining the mobility of an individual. These results will have high …

Supporting South Korea’S Aging Population: How Ai And Iot Acceptance Connects The Young And Old, Bobby Im

Master's Projects and Capstones

In 2024, South Korea surpassed every other nation by becoming the country with the lowest fertility rate (below 0.7%). Population decline will hinder future ability to care for their aging population and although the government and private corporations are investing millions of dollars on developing Artificial Intelligence-Internet of Things (AI-IoT) devices to support the aging, the acceptance levels and the amount of family support required is undervalued. By examining AI-IoT’s current use and role in South Korea’s public health system this paper shows how intergenerational support helps optimize existing procedures and equipment, increases the level of acceptance and use, and …

Αb-Crystallin Phosphorylation Induces A Condensatopathy To Worsen Post-Myocardial Infarction Cardiomyopathy, Md Moydul Islam

Arts & Sciences Graduate Student Theses and Dissertations

Rare genetic mutations in proteins expressed in cardiomyocytes lead to proteotoxic cardiomyopathies which are characterized by widespread protein-aggregate pathology. However, the mechanistic link between proteotoxicity and protein-aggregates in the more common ischemic cardiomyopathy remains unclear. Our study revealed the mis-localization of desmin, actin, and α-actinin to protein-aggregates in the myocardium of patients with ischemic cardiomyopathy and in mouse hearts undergoing post-myocardial infarction ventricular remodeling. These findings mimic observations in autosomal-dominant cardiomyopathy resulting from the R120G mutation in the chaperone protein CRYAB where desmin is mis-localized into the aggregates. Importantly, we observed increased phosphorylation of CRYAB at serine-59 (pS59-CRYAB) and its …

Obesity: The Effects On Health And Healthcare, Nadia Abdulbaki

Posters - 2024

▪ In 2022, 1 in 8 people in the world were living with obesity.

▪ 2.8 million people die each year due to being overweight and obese.

▪ Obesity is a medical disease that raises the likelihood of developing various conditions and diseases that increase the chances of mortality for affected individuals.

▪ Obesity can be caused by several influences, whether behavioral, socioeconomic, environmental, hormonal, or genetic; however, the primary cause of obesity is mostly attributed to lifestyle. Specifically, it is the consumption of a high amount of calories in conjunction with a low amount of calories expended. This is …

For Those Who Don't Know (How) To Ask: Building A Dataset Of Technology Questions For Digital Newcomers, Evan Lucas, Kelly S. Steelman, Leo Ureel, Charles Wallace

Michigan Tech Publications

While the rise of large language models (LLMs) has created rich new opportunities to learn about digital technology, many on the margins of this technology struggle to gain and maintain competency due to lexical or conceptual barriers that prevent them from asking appropriate questions. Although there have been many efforts to understand factuality of LLM-created content and ability of LLMs to answer questions, it is not well understood how unclear or nonstandard language queries affect the model outputs. We propose the creation of a dataset that captures questions of digital newcomers and outsiders, utilizing data we have compiled from a …

Preserving Linguistic Diversity In The Digital Age: A Scalable Model For Cultural Heritage Continuity, James Hutson, Pace Ellsworth, Matt Ellsworth

Faculty Scholarship

In the face of the rapid erosion of both tangible and intangible cultural heritage globally, the urgency for effective, wide-ranging preservation methods has never been greater. Traditional approaches in cultural preservation often focus narrowly on specific niches, overlooking the broader cultural tapestry, particularly the preservation of everyday cultural elements. This article addresses this critical gap by advocating for a comprehensive, scalable model for cultural preservation that leverages machine learning and big data analytics. This model aims to document and archive a diverse range of cultural artifacts, encompassing both extraordinary and mundane aspects of heritage. A central issue highlighted in the …

Mentoring Graduate Students For Academic Careers In Grassland Science, L. E. Sollenberger

IGC Proceedings (1977-2023)

Effective mentorship enhances student productivity and career achievements, yet faculty generally do not receive mentorship training, nor does mentorship receive focused attention, evaluation, and recognition. The objectives of this paper are to 1) define mentorship and identify roles of a mentor, 2) highlight qualities and outcomes of effective mentoring, and 3) elaborate best mentoring practices, metrics for assessing mentoring, and challenges for mentoring the next generation of grassland scientists. Mentoring is a professional alliance where individuals work together to support the personal and professional growth, development, and success of the relational partners. Mentors should be altruistic discipline experts, have substantial …

Qiditangshen Granules Alleviates Diabetic Nephropathy Podocyte Injury: A Network Pharmacology Study And Experimental Validation In Vivo And Vitro, Fei Gao, Ying Zhou, Borui Yu, Huidi Xie, Yang Shi, Xianhui Zhang, Hongfang Liu

Faculty, Staff and Student Publications

BACKGROUND: QiDiTangShen granules (QDTS), a traditional Chinese medicine (TCM) compound prescription, have remarkable efficacy in diabetic nephropathy (DN) patients, and their pharmacological mechanism needs further exploration.

METHODS: According to the active ingredients and targets of the QDTS in the TCMSP database, the network pharmacology of QDTS was investigated. The potential active ingredients were chosen based on the oral bioavailability and the drug similarity index. At the same time, targets for DN-related disease were obtained from GeneCards, OMIM, PharmGKB, TTD, and DrugBank. The TCM-component-target network and the protein-protein interaction (PPI) network were constructed with the Cytoscape and STRING platforms, respectively, and …

Ageannomo: A Knowledgebase Of Multi-Omics Annotation For Animal Aging, Kexin Huang, Xi Liu, Zhaocan Zhang, Tiangang Wang, Haixia Xu, Qingxuan Li, Yuhao Jia, Liyu Huang, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

Aging entails gradual functional decline influenced by interconnected factors. Multiple hallmarks proposed as common and conserved underlying denominators of aging on the molecular, cellular and systemic levels across multiple species. Thus, understanding the function of aging hallmarks and their relationships across species can facilitate the translation of anti-aging drug development from model organisms to humans. Here, we built AgeAnnoMO (https://relab.xidian.edu.cn/AgeAnnoMO/#/), a knowledgebase of multi-omics annotation for animal aging. AgeAnnoMO encompasses an extensive collection of 136 datasets from eight modalities, encompassing 8596 samples from 50 representative species, making it a comprehensive resource for aging and longevity research. AgeAnnoMO characterizes …

Progression Magazine, 2023-2024, Coastal Carolina University

Progression Magazine

Magazine of the Gupta College of Science at Coastal Carolina University.

Outpatient Fall Prevention In Ambulatory Adults 65 Years Old And Over, Dorothy L. Osborne-White

Doctor of Nursing Practice (DNP) Scholarly Projects - Archive

Background: In the United States (U.S.), falls are the leading cause of injury among adults 65 and over, resulting in 36 million falls yearly (Moreland et al., 2020). According to the Centers for Disease Control and Prevention (CDC, 2023), one in four older adults experiences a fall each year. Falls are the world's second most prominent cause of accidental deaths (World Health Organization [WHO], 2021). Falls are the leading cause of both fatal and non-fatal injuries among older adults (Moreland et al., 2020).

Methods: A quality improvement project that included a fall bundle was implemented in a primary clinic. A …

Gerontovis: Data Visualization At The Confluence Of Aging, Zack While, R. Jordan Crouser, Ali Sarvghad

Computer Science: Faculty Publications

Despite the explosive growth of the aging population worldwide, older adults have been largely overlooked by visualization research. This paper is a critical reflection on the underrepresentation of older adults in visualization research. We discuss why investigating visualization at the intersection of aging matters, why older adults may have been omitted from sample populations in visualization research, how aging may affect visualization use, and how this differs from traditional accessibility research. To encourage further discussion and novel scholarship in this area, we introduce GerontoVis, a term which encapsulates research and practice of data visualization design that primarily focuses on older …

Cancer Survivorship And Subjective Cognitive Decline In The Us: Results From A Nationally Representative Sample, Monique J. Brown, Ally Hucek, Jingkai Wei, Loretta Anderson, Muzi Na

Faculty Publications

Cancer may be associated with objective cognitive decline. However, studies examining the link between cancer and subjective cognitive decline (SCD), which occurs earlier during cognitive trajectories, are lacking. In addition, research assessing risk factors for SCD among cancer survivors is scant. Therefore, this study aimed to examine the association between cancer and SCD in the past year, and assess the association between age of diagnosis, cancer treatment, and SCD among cancer survivors. Data were obtained from the 2021 Behavioral Risk Factor Surveillance System (N=15,447). Crude and adjusted logistic regression models, controlling for sociodemographic characteristics, were used to determine the association …

Study Of Human Circadian Protein (Hrory) And Lipid-Protein Interaction In Giant Virus (Pbcv-1), Laila Noor

Open Access Theses & Dissertations

Project 1: Circadian rhythm is a 24-hour cycle that regulates physical and behavioral changes such as sleep-wake patterns in humans, tailoring the daily light and dark changes. Long-term disruption in circadian rhythms can cause sleep disorders such as sleep apnea, insomnia, et al. Limited research has been done on potential drugs to treat against circadian related sleep disorders. Inside the cell at molecular level, the circadian rhythm is regulated by interlocked time-delayed feedback loops, which involve positive and negative transcriptional regulators. Experimental results showed transcriptional factors Retinoic Acid Receptor-Related Orphan Receptors (RORs) improve the stability and functionality of the circadian …

The Use Of Deception In Dementia-Care Robots: Should Robots Tell "White Lies" To Limit Emotional Distress?, Samuel R. Cox, Grace Cheong, Wei Tsang Ooi

ROSA Journal Articles and Publications

With projections of ageing populations and increasing rates of dementia, there is need for professional caregivers. Assistive robots have been proposed as a solution to this, as they can assist people both physically and socially. However, caregivers often need to use acts of deception (such as misdirection or white lies) in order to ensure necessary care is provided while limiting negative impacts on the cared-for such as emotional distress or loss of dignity. We discuss such use of deception, and contextualise their use within robotics.

Economic Equity And People With Disabilities: Development And Characterization Of A Novel Index, Bhavneet Walia, Katherine Mcdonald, Joy Hammel, Lex Frieden, Michael Morris, Barry Whaley, Vinh Nguyen

Faculty, Staff and Student Publications

Here we develop two new social indices: The ADA PARC Absolute Economic Opportunity Index and the ADA PARC Relative Economic Opportunity Index. These indices allow us novel examinations of economic equity between people with and without disabilities within a U.S. State and between people with disabilities in different states using aggregations of multiple component economic indicators. These represent the first efforts to offer U.S. indices of this focus, an important development given the distinct economic needs of people with disabilities and the value in accounting for distinct national policies. The indices rely on U.S. Census and other data on economic …

Environmental Loss, Displacement, And Anxiety In Portugal: Analyzing News Articles To Differentiate Manifestations Of Environmental Distress, Robin Greene

Independent Study Project (ISP) Collection

Expressions of environmental distress can take different forms, with different symptoms, causes, and treatments. Existing literature generally identifies three primary categories of environmental distress responses: environmental grief, solastalgia, and eco-anxiety. This paper explores these distinctions and identifies words typically associated with each category in Portuguese news articles using Latent Dirichlet Allocation (LDA). LDA is a Natural Language Processing (NLP) technique that groups words into topics and identifies connections between those words based on how often those words appear together in sequences. This paper uses a modified LDA algorithm called GuidedLDA to identify additional keywords within topics defined by a list …

Designing A Human-Centered Intelligent System To Monitor & Explain Abnormal Patterns Of Older Adults, Min Hun Lee, Daniel P. Siewiorek, Alexandre Bernardino

Research Collection School Of Computing and Information Systems

Older adult care technologies are increasingly explored to support the independent living of older adults by monitoring their abnormal activities and informing caregivers to provide intervention if necessary. However, the adoption of these technologies remains challenging due to several factors (e.g. lack of usability). In this work, we present a human-centered, intelligent system for older adult care. Our proposed designs of the system were created based on the findings from a focus group session with caregivers. This system monitors the abnormal activities of an older adult using wireless motion sensors and machine learning models. In addition, unlike previous work that …

Singapore's Hospital To Home Program: Raising Patient Engagement Through Ai, John Abisheganaden, Kheng Hock Lee, Lian Leng Low, Eugene Shum, Han Leong Goh, Christine Gian Lee Ang, Andy Wee An Ta, Steven M. Miller

Research Collection School Of Computing and Information Systems

Because of their complex care needs, many elderly patients are discharged from hospitals only to be readmitted for multiple stays within the following twelve months. John Abisheganaden and his fellow authors describe Singapore’s Hospital to Home program, a community care initiative fueled by artificial intelligence.

Enhancing Health Tweet Classification: An Evaluation Of Transformer-Based Models For Comprehensive Analysis, Foram Pankajbhai Patel

Computer Science and Engineering Theses - Archive

The task of health tweet classification entails identifying whether a given tweet is health-related or not. While existing research in this area has made significant progress in classifying tweets into specific sub-domains of health, such as mental health, COVID-19, or specific diseases, there is a need for a more comprehensive approach that considers a broader range of health-related topics. This thesis addresses this need by proposing a diverse and comprehensive dataset that includes various existing health-related datasets, data collected through a keyword-based approach, and manually annotated data. However, the use of health-related keywords in a figurative or non-health context poses …

Co-Designing Assistive Technology With And For Persons Living With Dementia, Dympna O'Sullivan, Jonathan Turner, Siobhan O'Neill, Micheal Wilson, Julie Doyle

Conference papers

Dementia is a chronic and progressive neurodegenerative illness, which can lead to significant difficulties in a person’s capacity to perform activities of daily living (ADLs) and engage in meaningful activities. There is an acute need, which digital health technologies can potentially fulfil, to provide proactive support for persons living with dementia (PLwD) and their caregivers. However, there is limited involvement of PLwD in the design of technology that could be used to support their personal plans for independent living at home. In this paper, we describe how we are employing a co-design methodology to support engagement in an assistive technology …

Air Temperature And Diet Are Not Associated With Oxygen Consumption Rate In Banded Crickets, Gryllodes Sigillatus, Nicole Bailey, Connor Oakes, Rachel Sleeth, Mallorie Smith

Butler Journal of Undergraduate Research

All living organisms acclimate to their environments, with ectothermic species particularly susceptible to environmental change, specifically temperature. Ectothermic insects like crickets directly alter their physiological processes depending on the environment in which they live. Temperature is vital in regulating processes such as metabolism, respiration, and reproduction, among other things. What remains unclear is how a change in the environment, specifically extreme temperature change and dietary alterations, affects physiological processes. In this study, we performed experiments on ectothermic banded crickets to examine the effects of temperature change and the interaction of temperature and diet on oxygen consumption. For both experiments, we …

Work-Life And Health Experiences Of Computer Science Faculty Parents Of Children With Developmental Disabilities During Covid-19, Molly Armstrong

Butler Journal of Undergraduate Research

Prior to the COVID-19 pandemic, parents of children with developmental disabilities (PCDD) had been shown to experience more stress than parents of children without developmental disabilities (non-PCDD). COVID-19 may have exacerbated difficulties for PCDD. To compare differences in COVID-19 experiences between PCDD and non-PCDD, 202 parents working as computer science (CS) faculty reported their experiences of mental health symptoms, physical health symptoms, work-life conflict levels as experienced during the pandemic, and any changes in their childcare responsibilities because of COVID-19. Participants completed surveys on their experiences during Fall 2020 and Spring 2021, the first academic year after the start of …

Longitudinal Changes In Alzheimer’S-Related Plasma Biomarkers And Brain Amyloid, Murat Bilgel, Abhay Moghekar, Henrik Zetterberg, Bruno Jedynak, Multiple Additional Authors

Mathematics and Statistics Faculty Publications and Presentations

Introduction Understanding longitudinal plasma biomarker trajectories relative to brain amyloid changes can help devise Alzheimer’s progression assessment strategies.

Methods We examined the temporal order of changes in plasma amyloid-β ratio (Aβ42/Aβ40), glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), and phosphorylated tau ratios (p-tau181/Aβ42, p-tau231/Aβ42) relative to 11C-Pittsburgh compound B (PiB) positron emission tomography (PET) cortical amyloid burden (PiB−/+). Participants (n = 199) were cognitively normal at index visit with a median 6.1-year follow-up.

Results PiB groups exhibited different rates of longitudinal change in Aβ42/Aβ40 (β = 5.41 × 10-4, SE = 1.95 × 10-4, p = 0.0073). …

Filling In The Gaps: A Multiple Imputation Approach To Estimating Aging Curves In Baseball, Quang Nguyen, Gregory J. Matthews

Mathematics and Statistics: Faculty Publications and Other Works

In sports, an aging curve depicts the relationship between average performance and age in athletes' careers. This paper investigates the aging curves for offensive players in the Major League Baseball. We study this problem in a missing data context and account for different types of dropouts of baseball players during their careers. In particular, the performance metric associated with the missing seasons is imputed using a multiple imputation model for multilevel data, and the aging curves are constructed based on the imputed datasets. We first perform a simulation study to evaluate the effects of different dropout mechanisms on the estimation …

Chacahoula 2022, Tram Phan

Chacahoula

Chacahoula 2022 includes the people and events that made the 2021-2022 school year at University of Louisiana at Monroe unique. Staff included

Tram Phan, Editor-in-Chief

Feature Writers:

Amir Alnajjar

Hanna Flynn

Alayna Pellegrin

Tram Phan

Evan Ranjitkar

Koshish Shrestha

Zoe Sissac

Tia Smith

Sports Writers:

Jonah Bostick

Cameron Jett

Designers:

Hanna Flynn

Tram Phan

Photographers:

Lanaya Bolden

Skylar Henry

Jeanette Robinson

Saugat Shrestha

Calli Sinclair

Paul Ware

The Influence Of Place Attachment On Farmers’ Succession Plans: A Mixed Methods Study, M. E. Burbach, S. M. Kennedy, S. J. Kunert

School of Natural Resources: Faculty Publications

No abstract provided.

A Growth Model For Arctica Islandica: The Performance Of Tanaka And The Temptation Of Von Bertalanffy—Can The Two Coexist?, John M. Klinck, Eric N. Powell, Kathleen M. Hemeon, Jillian R. Sower, Daniel R. Hennen

CCPO Publications

Organisms increase in size over time (age) due to excess assimilation over metabolic (respiration) energy demands. Most organisms reach a maximum size with increasing age as gain and loss balance. The von Bertalanffy length-at-age relationship, which is commonly used in fishery assessment calculations, imposes such a maximum size. However, some fished species, such as ocean quahogs, Arctica islandica, are long lived and continue to grow at old age. The Tanaka age-at-length relationship has continued growth at old age, but is rarely used in stock assessment models. A modified form of the von Bertalanffy model is presented, which mimics the …

Co-Design Of An Interactive Wellness Park: Exploring Design Requirements For A Multimodal Outdoor Physical Web Installation With Older Adults, Fatima Badmos

Academic Posters Collection

The global demographic landscape is experiencing a notable shift, characterised by a growing proportion of adults over 60. According to projections, the proportion of individuals aged 60 and above is expected to reach one-sixth of the global population by 2030. Furthermore, by 2050, this demographic is projected to exceed a staggering two billion people. Amidst this shift, there is an urgent need to develop interactive and innovative solutions to address older adults' unique challenges, particularly in outdoor physical activity.

A co-design methodology involving older adults’ participation from the idea generation to the application development process will be adopted to address …

Aging After Stroke: How To Define Post-Stroke Sarcopenia And What Are Its Risk Factors?, Sheng Li, Javier Gonzalez-Buonomo, Jaskiran Ghuman, Xinran Huang, Aila Malik, Nuray Yozbatiran, Elaine Magat, Gerard E Francisco, Hulin Wu, Walter R Frontera

Faculty, Staff and Student Publications

BACKGROUND: Sarcopenia, generally described as "aging-related loss of skeletal muscle mass and function", can occur secondary to a systemic disease.

AIM: This project aimed to study the prevalence of sarcopenia in chronic ambulatory stroke survivors and its associated risk factors using the two most recent diagnostic criteria.

DESIGN: A cross-sectional observational study.

SETTING: A scientific laboratory.

POPULATION: Chronic stroke.

METHODS: Twenty-eight ambulatory chronic stroke survivors (12 females; mean age=57.8±11.8 years; time after stroke=76±45 months), hand-grip strength, gait speed, and appendicular skeletal muscle mass (ASM) were measured to define sarcopenia. Risk factors, including motor impairment and spasticity, were identified using regression …