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Articles 2641 - 2670 of 91781
Full-Text Articles in Entire DC Network
The Colorado River: Searching For Solutions In The Face Of Uncertainty: Conference Summary, Emilia Endara, Douglas Kenney
The Colorado River: Searching For Solutions In The Face Of Uncertainty: Conference Summary, Emilia Endara, Douglas Kenney
Books, Reports, and Studies
The Colorado River is facing unprecedented change and uncertainty. Average annual flows continue to decline, and negotiations to craft post-2026 guidelines to manage the river have repeatedly bogged down in disagreements about delivery obligations, sharing shortages, and mandatory conservation. While some clarity may emerge in the coming months, the ability to sustain many existing municipal and agricultural water users is already being compromised. Meanwhile, there is growing recognition that a durable resolution must also address the water rights of sovereign Tribal Nations and better integrate environmental values into river management. All sovereigns, stakeholders, and sectors must work together now more …
Thirst For Data: State Responses To Data Center Water Use, Daniel Anderson, Sydney Stellato
Thirst For Data: State Responses To Data Center Water Use, Daniel Anderson, Sydney Stellato
Books, Reports, and Studies
No abstract provided.
The Influence Of Scale In Modeling Social Vulnerability And Disaster Assistance, Sina Razzaghi Asl, Oronde Drakes, Eric Tate, Samuel Brody, Wesley Highfield, Kayode Atoba
The Influence Of Scale In Modeling Social Vulnerability And Disaster Assistance, Sina Razzaghi Asl, Oronde Drakes, Eric Tate, Samuel Brody, Wesley Highfield, Kayode Atoba
Political Science & Geography Faculty Publications
Understanding how social vulnerability relates to disaster impacts is critical for addressing social equity, yet the role of spatial scale in this relationship is often overlooked. Most studies use aggregated data, risking ecological fallacy-misinterpreting individual outcomes from group-level data. This study examines how spatial scale influences the relationship between social vulnerability and federal disaster assistance after Hurricane Harvey. Using spatial econometric models at both household and census tract levels, we assessed the strength of key vulnerability indicators in explaining disaster assistance. Results show that disability, housing tenure, household size, and income predict assistance at the household level, but their influence …
Synthesis Of The Naga(S1−Xsex)2 Solid Solution From Mechanically Activated Precursors, Louisiane Verger, Julien Trébosc, Santhoshkumar Sundaramoorthy, Amitava Choudhury, Olivier Hernandez, Eric Furet, Sébastien Chenu, David Le Coq, Laurent Calvez, Olivier Lafon
Synthesis Of The Naga(S1−Xsex)2 Solid Solution From Mechanically Activated Precursors, Louisiane Verger, Julien Trébosc, Santhoshkumar Sundaramoorthy, Amitava Choudhury, Olivier Hernandez, Eric Furet, Sébastien Chenu, David Le Coq, Laurent Calvez, Olivier Lafon
Chemistry Faculty Research & Creative Works
NaGaS2 and NaGaSe2 are two recently discovered compounds that crystallize in the same structure type. In this work, NaGa(S1−xSex)2 (x = 0.5, 0.75 and 1) are prepared using an alternative synthesis route, mechanochemistry followed by heat treatment. Na2S, Na2Se, Ga2S3 and Ga2Se3 are milled in stoichiometric proportions. Differential scanning calorimetry, X-ray diffraction and solid-state nuclear magnetic resonance (23Na and 71Ga) show that the compounds after milling are composed of crystalline NaGa(S1−xSex)2 with an amorphous part. …
Driving Into The Past: Road Logs And The History And Geology Of The Eastern Sierra Of California, Char Miller
Driving Into The Past: Road Logs And The History And Geology Of The Eastern Sierra Of California, Char Miller
Eastern Sierra History Journal
Road Logs are a pedagogical tool that geologists use on field trips with their students. Dee Trent's 1982 Road Log, which reproduced in this issue of ESHJ, also functions as a cultural artifact; it demonstrates what was known then, and how that scientific knowledge and the human geography of the region has changed over time.
Last Glacial Maximum And Late Glacial Aeolian Sand Activity, South-Central Indiana, Usa, H. M. Loope, J. L. Antinao, P.R. Hanson, P. M. Jacobs, D. A. Grimley
Last Glacial Maximum And Late Glacial Aeolian Sand Activity, South-Central Indiana, Usa, H. M. Loope, J. L. Antinao, P.R. Hanson, P. M. Jacobs, D. A. Grimley
Conservation and Survey Division: Faculty and Staff Publications
No abstract provided.
Enhanced Hydrophilicity And Self-Cleaning Properties Of Tio₂ Thin Films On Glass For Photovoltaic Applications: Influence Of Precursor Concentration And Light Irradiation, Fatma Refaat, Hany Hashem, Mohamed Mahmoud Gouda, Ibrahim Ahmed, Khaled Abdelwahed, Ahmed Bakr El Basaty
Enhanced Hydrophilicity And Self-Cleaning Properties Of Tio₂ Thin Films On Glass For Photovoltaic Applications: Influence Of Precursor Concentration And Light Irradiation, Fatma Refaat, Hany Hashem, Mohamed Mahmoud Gouda, Ibrahim Ahmed, Khaled Abdelwahed, Ahmed Bakr El Basaty
Trends in advanced sciences and technology
This study investigates the modification of glass substrates with TiO₂ thin films to enhance surface hydrophilicity and self-cleaning behavior. The films were deposited on glass by spin coating using different precursor concentrations, followed by thermal treatment. Structural and optical properties were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and UV–Vis spectroscopy, while surface wettability was evaluated through water contact angle measurements. XRD confirmed the formation of pure anatase TiO₂, while FTIR spectra verified the presence of Ti–O and Ti–O–Ti bonds. Wettability analysis showed that films prepared with the lowest precursor concentration exhibited the …
Arrangements Of N Planes Resulting In One Bounded Tetrahedral Chamber, Ava Knight
Arrangements Of N Planes Resulting In One Bounded Tetrahedral Chamber, Ava Knight
Williams Honors College, Honors Research Projects
This paper investigates the combinatorial geometry of plane arrangements in three-dimensional space, focusing on configurations that produce exactly one bounded tetrahedral chamber. We define T(n) as the number of face-combinatorial equivalence classes of arrangements of n planes in ℝ³ containing exactly one bounded tetrahedral chamber. Known values — T(3) = 0, T(4) = 1, and T(5) = 2 — are established through direct construction, while T(6) remains an open problem. This paper contributes experimental evidence toward resolving T(6) by systematically extending the two valid 5-plane arrangements and verifying, through a plane removal argument, that each yields a valid plane configuration …
Machine Learning For Recession Prediction, Ethan Reusser
Machine Learning For Recession Prediction, Ethan Reusser
Williams Honors College, Honors Research Projects
Macroeconomic predictions present challenges in machine learning due to the rarity of economic recessions, the constantly-changing matter of global markets, and severe class imbalance in historical data. This project focuses on predicting the onset of United States economic recessions within a 12-month window using Python and Jupyter Notebook. A machine learning pipeline was developed utilizing multiple models: Logistic Regression, Random Forest, XGBoost, and Long Short-Term Memory (LSTM) neural networks. For class imbalance, the Synthetic Minority Over-sampling Technique (SMOTE) was applied strictly to training data, paired with Platt scaling for calibration on thresholds. The resulting models were evaluated in the 2005 …
Overview And Methods Of Molecular Paleontology: A Review, Shelby Touchstone
Overview And Methods Of Molecular Paleontology: A Review, Shelby Touchstone
Williams Honors College, Honors Research Projects
Molecular paleontology—the study of ancient biomolecules preserved in fossils and sediments, including ancient DNA, lipids, and proteins—has motivated researchers since the 1950s, inspiring both scientific inquiry and broader cultural imagination. Think Jurassic Park. This honors thesis presents a comprehensive review of the history, current state, and methods of the field of molecular paleontology. Drawing on peer-reviewed literature and scholarly resources accessed through databases such as EBSCO and Bierce library, this review examines key techniques such as Next Generation Sequencing and amino acid racemization and will go over limitations and controversies in the field. It will also explore potential new …
Computer-Aided Molecular Design To Identify More Environmentally Friendly Pfas, Melvin M. Keita
Computer-Aided Molecular Design To Identify More Environmentally Friendly Pfas, Melvin M. Keita
Williams Honors College, Honors Research Projects
The goal of this project is to inversely design alternatives to per- and polyfluoroalkyl substances (PFAS) using Computer-Aided Molecular Design (CAMD). PFAS, also described as “forever chemicals”, have been used in industry and consumer products since the 1940s. PFAS can be found in drinking water, food, food packaging, waste sites, and other sources. Exposure to different PFAS can lead to increased risks of some cancers, immune effects, and reproductive effects. Pulling from existing data, this project will use quantitative structure-property relationships (QSPRs) to design PFAS alternatives that possess optimal properties to prevent adsorption into drinking water and other potential sources …
A Decade Of Programming Languages: Trends In Popularity And Influence, Jonathan C. Erb
A Decade Of Programming Languages: Trends In Popularity And Influence, Jonathan C. Erb
Williams Honors College, Honors Research Projects
Programming languages play a central role in open-source software ecosystems, yet their adoption, visibility, and influence shift over time as technologies, developer communities, and industry practices evolve. The study aims to investigate long-term trends in programming-language usage on GitHub from 2014 through 2024, focusing on ten major languages that represent diverse domains and ecosystems. Using repository metadata, engagement metrics such as stars and forks, and language-level code statistics measured with cloc, the analysis will examine changes in repository creation, code contribution volume, and popularity. Since popularity remains an unsettled and multidimensional concept, part of this research involves determining how it …
Land Cover Classification Using Optimized Imagery Resolution And Machine Learning Algorithms For A Long-Term Monitoring And Restoration Project, Jessica R. Suoja
Land Cover Classification Using Optimized Imagery Resolution And Machine Learning Algorithms For A Long-Term Monitoring And Restoration Project, Jessica R. Suoja
Cal Poly Humboldt theses and projects
Ecosystem services and functions are prone to water resource exploitation resulting in cascading effects that include decrease of biodiversity and loss of riparian vegetation, a keystone habitat in desert riparian ecosystems. Mono Lake is a prime example of overexploitation of water resources leading to legal action and eventually a legally mandated long-term monitoring and restoration project. Monitoring and restoration projects can benefit from techniques such as remote sensing and machine learning algorithms to generate accurate land cover classification maps for calculating land cover change over time. However, the spatial resolution of remote sensing imagery and the machine learning algorithms chosen …
Self-Calibrating Uav Navigation: Reinforcement Learning Approaches For Horizontal Trajectory Estimation, Shirin Nasr-Esfahani, S. Jagannathan
Self-Calibrating Uav Navigation: Reinforcement Learning Approaches For Horizontal Trajectory Estimation, Shirin Nasr-Esfahani, S. Jagannathan
Electrical and Computer Engineering Faculty Research & Creative Works
Accurate unmanned aerial vehicle (UAV) trajectory estimation is essential for autonomous navigation, particularly in GPS-denied environments. Visualodometry and simultaneous localization and mapping (SLAM) approaches require precise camera intrinsic parameters, which are typically obtained through predefined or offline calibration. Instead, in this work, we propose a reinforcement learning (RL)-based self-calibration framework that estimates camera intrinsic parameters directly from monocular video sequences, without requiring prior knowledge of the camera, environment, or calibration targets. This intrinsic parameter estimation is then leveraged to achieve robust UAV trajectory estimation using only video data. We formulate the problem as a sequential decision-making task, where an RL …
Automated Writer And Acquisition-Condition Classification Of Digitally Captured Handwriting Using Statistical Dynamic Features And Support Vector Machines, Long-Huang Tsai, Hsiang-Ju Lai, Wen-Chao Yang, Jiajun Jiang, Chung-Hao Chen
Automated Writer And Acquisition-Condition Classification Of Digitally Captured Handwriting Using Statistical Dynamic Features And Support Vector Machines, Long-Huang Tsai, Hsiang-Ju Lai, Wen-Chao Yang, Jiajun Jiang, Chung-Hao Chen
Electrical & Computer Engineering Faculty Publications
Digitally captured handwriting preserves pen trajectories and dynamic signals, but it also records hardware- and input-dependent properties that can confound forensic interpretation. This study revises a support vector machine (SVM) screening framework using 16,500 samples from 30 writers, 11 writing-content categories, and five acquisition conditions spanning three tablets and stylus or finger input. Twenty-four raw and derived time-series variables were summarized by maximum, minimum, mean, median, and standard deviation, yielding 120 features; the mode statistic was removed. Writing direction and angular velocity were recalculated with atan2-based vector formulas. Unavailable device/API channels were encoded as zero, and Z-score parameters were estimated …
Regulating Galaxy Growth: Ionized Gas Conditions, Star Formation Histories, And Environmental Effects, Shweta Jain
Regulating Galaxy Growth: Ionized Gas Conditions, Star Formation Histories, And Environmental Effects, Shweta Jain
University of Kentucky Doctoral Dissertations
Understanding galaxy formation and evolution requires tracing how baryons cycle between stars, gas, and the interstellar medium (ISM) across cosmic time. The efficiency of star formation, the buildup of metals, and the regulation of gas inflows and outflows are governed by evolving physical conditions within galaxies and their environments. My thesis investigates how the ionized ISM, star formation histories, and environmental processes have shaped galaxy evolution over the past ∼ 12 Gyr. The primary focus of this work is the evolution of the physical conditions of ionized gas in galaxies, including gas-phase metallicity and ionization state. Using new and archival …
Standardization Of Neuromuscular Reflex Analysis—Role Of Fine-Tuned Vision-Language Model Consortium And Openai Gpt-Oss Reasoning Llm-Enabled Decision Support System, Eranga Bandara, Ross Gore, Sachin Shetty, Ravi Mukkamala, Christopher K. Rhea, Brittany S. Samulski, Amin Hass, Atmaram Yarlagadda, Shaifali Kaushik, Malith De Silva, Andriy Maznychenko, Inna Sokolowska, Kasun De Zoysa
Standardization Of Neuromuscular Reflex Analysis—Role Of Fine-Tuned Vision-Language Model Consortium And Openai Gpt-Oss Reasoning Llm-Enabled Decision Support System, Eranga Bandara, Ross Gore, Sachin Shetty, Ravi Mukkamala, Christopher K. Rhea, Brittany S. Samulski, Amin Hass, Atmaram Yarlagadda, Shaifali Kaushik, Malith De Silva, Andriy Maznychenko, Inna Sokolowska, Kasun De Zoysa
VMASC Publications
Background/Objectives: Accurate assessment of neuromuscular reflexes, such as the Hoffmann reflex (H-reflex), plays a critical role in sports science, rehabilitation, and clinical neurology. Conventional interpretation of H-reflex electromyography (EMG) waveforms is subject to inter-rater variability and interpretive bias, limiting reliability and standardization. This study aims to develop an automated, interpretable, and robust agentic AI–driven framework for H-reflex waveform analysis. Methods: We propose a fine-tuned Vision–Language Model (VLM) consortium combined with a reasoning Large Language Model (LLM)–enabled decision support system for automated H-reflex interpretation. Multiple VLMs were fine-tuned on curated datasets of H-reflex EMG waveform images annotated with expert clinical observations, …
Distilling The Complexity Of Agent-Based Simulations Into Textual Explanations Via Large Language Models, Noé Y. Flandre, Philippe J. Giabbanelli
Distilling The Complexity Of Agent-Based Simulations Into Textual Explanations Via Large Language Models, Noé Y. Flandre, Philippe J. Giabbanelli
VMASC Publications
Communicating the design and results of agent-based models (ABMs) to subject matter experts is challenging, which hinders participation and limits trust in simulation-based decision support. Large language models (LLMs) can communicate ABMs as textual summaries, thus complementing traditional disclosure through statistical and visualization techniques. While prior work translated the structure of conceptual models into narratives via LLMs, our extension covers the dynamics of simulation models via an automated simulation-to-text method that extracts contextual information from NetLogo ABMs, performs repeated simulations, and generates narrative descriptions (including the model’s purpose, parameters, and simulation dynamics) using mutimodal LLMs. Furthermore, four summarization algorithms spanning …
Machine Learning Classification Of Prostate Cancer Genomic Sequences Using K-Mer And Sequence-Derived Features, Kuldeep Rawat, Hirendra Nath Banerjee, Jamie Noble, Saa Naudia Deloatch, Satyendra Banerjee, Sachin Shetty, Soumya Banerjee
Machine Learning Classification Of Prostate Cancer Genomic Sequences Using K-Mer And Sequence-Derived Features, Kuldeep Rawat, Hirendra Nath Banerjee, Jamie Noble, Saa Naudia Deloatch, Satyendra Banerjee, Sachin Shetty, Soumya Banerjee
VMASC Publications
Prostate cancer disproportionately impacts African American men, who experience significantly higher mortality rates and earlier disease onset than other populations. Current diagnostic approaches, including prostate-specific antigen testing and biopsy, lack sufficient specificity and sensitivity, underscoring the need for accurate, molecular-level classification tools. This paper presents a machine learning framework for binary classification of genomic DNA sequences as cancerous or healthy. A dataset of 1684 FASTA-formatted sequences obtained from the National Library of Medicine - GenBank was analyzed, with 1662 sequences retained after quality control filtering. Feature engineering yielded 67 attributes, including GC content, Shannon entropy, sequence length, and trinucleotide k-mer …
Dyno : Dynamic Neurosymbolic Orchestrator For Multi-Agent Systems, Ritvik Garimella, Chathurangi Shyalika, Renjith Prasad, Amit Sheth
Dyno : Dynamic Neurosymbolic Orchestrator For Multi-Agent Systems, Ritvik Garimella, Chathurangi Shyalika, Renjith Prasad, Amit Sheth
Publications
Large Language Model (LLM)-based multi-agent systems (LaMAS) represent an emerging paradigm for tackling complex, multi-step reasoning and decision-making problems. As these systems scale, orchestration, which is the ability to coordinate, manage, and evaluate the interactions among diverse agents, becomes central to their success. While recent orchestrators such as AgentFlow have demonstrated promise in managing communication and task delegation, they remain limited in their ability to understand task semantics, coordinate heterogeneous agent types (e.g., reactive vs. cognitive), and adaptively align outputs with human-defined goals. In this position paper, we introduce the DYNO (Dynamic Neurosymbolic Orchestrator), a system developed as part of …
Using Nmr Spectroscopy And Linear Discriminant Analysis To Molecular Profile Varietal Honey, Taylor Mac
Using Nmr Spectroscopy And Linear Discriminant Analysis To Molecular Profile Varietal Honey, Taylor Mac
Master's Theses and Doctoral Dissertations
In recent years, varietal honey has been a massive target of adulteration through mislabeling and the addition of other sugars. Unethical companies do this to cut production costs while still charging the consumer full price. Previous studies have used nuclear magnetic resonance (NMR) to unravel possible adulteration in honey, but currently, there are no standard rapid methods to authenticate varietal honey. In our research, we collected NMR signatures (“fingerprints”) and combined them with linear discriminant analysis (LDA) to predict the varietal, country, and region of varietal honey. As a part of the project, we investigated whether an adjustment to the …
Time Series Decomposition And Forecasting Of Alzheimer’S Disease Mortality Using A Kolmogorov-Zurbenko Filter, Jack D. Farrell
Time Series Decomposition And Forecasting Of Alzheimer’S Disease Mortality Using A Kolmogorov-Zurbenko Filter, Jack D. Farrell
Electronic Theses & Dissertations (2024 - present)
Alzheimer’s disease mortality has substantially risen in recent history, placing a significant burden on public health infrastructure and highlighting the need for improved analytical methods to better understand mortality data patterns and offer reliable predictions. Time series methods often struggle to balance both accuracy and interpretability, which hinders the ability to gather meaningful insights from time series data. To address these limitations, this study applies the Kolmogorov-Zurbenko (KZ) filter to monthly U.S. Alzheimer’s mortality data spanning from 1999 to 2023 and decomposes the series into long-term trend, seasonal, and noise components on a logarithmic scale. Long-term trend accounts for 86.49% …
Solving High-Dimensional Differential Equations Using Recurrent And Residual Neural Network Architectures, Hind Khaled Kolaib
Solving High-Dimensional Differential Equations Using Recurrent And Residual Neural Network Architectures, Hind Khaled Kolaib
Knowledge Engineering and Data Science
High-dimensional Partial Differential Equations (PDEs) form the foundation of complex process modeling in various scientific and engineering applications, including finance, physics, and optimal control. However, classical numerical methods are adversely affected by the curse of dimensionality, making them inapplicable for large-scale problems. Recently, however, deep learning-based approaches have provided a new toolbox for these high-dimensional PDEs, including methods such as the Deep Backward Stochastic Differential Equation (Deep BSDE) method. Our approach draws on a more sophisticated deep learning backbone, using neural networks (in our case, a Residual Neural Network and a Long Short-Term Memory network (LSTM) integrated into the Deep …
Innovative Methods In Intact Rock Deformation Detection, Ali Abdullah M Alzahrani
Innovative Methods In Intact Rock Deformation Detection, Ali Abdullah M Alzahrani
Doctoral Dissertations
"An accurate assessment of intact rock deformation is imperative in engineering activities carried out either in or above rock masses. However, instruments used for post-peak deformation are easily debonded and cannot record the whole process of post-peak deformation required in the failure modeling of rocks. This dissertation focuses on the investigation of the performance of two non-contact measuring systems (Laser Displacement Sensor (LDS) and Inductive Proximity Sensor (IPS)) compared to the contact type instrument (conventional Strain Gauge System (SGS)) in monitoring intact rock deformations. Subsequently, an IPS was installed in a high-pressure triaxial testing system before investigating its performance in …
The Spacetime Finite Element Method For Investigations Into Physics Ghost Systems And Time Parallel Preconditioning, Jax Wysong
Electronic Theses and Dissertations
This work operates on two fronts, focusing on interesting physical phenomena before turning our attention to an interesting numerical math problem. First, using the spacetime finite element method (FEM), we investigate a PDE system consisting of two Klein Gordon equations, which are coupled nonlinearly through the potential energy. The system contains a ghost (negative kinetic energy term). Systems such as these are generally deemed physically unstable, resulting in infinite energy in finite time. However, recent work has shown that this is not always the case. We investigate multiple scenarios arising from different initial conditions to characterize if/when a ghost system …
To Print A Remake: An Analysis Of Hollywood Remakes And Their Cultural Value, Connor F. Seaton
To Print A Remake: An Analysis Of Hollywood Remakes And Their Cultural Value, Connor F. Seaton
Honors Undergraduate Theses
In recent years, audiences and movie critics have expressed concern that Hollywood’s growing reliance on remakes, sequels, franchises, and similar adaptations has led to a broader worry that originality is fading from modern cinema and that the industry is instead focused on using adaptations to maximize profits. Although adaptation is often seen as a commercially driven framework for reproducing existing intellectual property in a new media format, this thesis argues that it should be recognized as an autonomous cultural category with its own artistic, historical, and social significance and merit. By analyzing adaptation scholarship and reviewing its complex historical development, …
A Comparative Evaluation Of Data Imbalance Handling Techniques In Machine Learning Models For One-Year Mortality Prediction In Liver Cirrhosis, Sumiya Hasan Trisha
A Comparative Evaluation Of Data Imbalance Handling Techniques In Machine Learning Models For One-Year Mortality Prediction In Liver Cirrhosis, Sumiya Hasan Trisha
UNF Graduate Theses and Dissertations
Liver cirrhosis is associated with substantial morbidity and mortality, making one-year mortality prediction a clinically relevant problem. Using a liver cirrhosis dataset as the motivating application, this thesis evaluates five machine learning classifiers—Logistic Regression, Random Forest, XGBoost, LightGBM, and CatBoost—under five class-imbalance handling strategies: Baseline learning, Random Oversampling, SMOTE-NC, ADASYN, and Cost-Sensitive Learning. Hyperparameter tuning was conducted using randomized search, and predictive performance was assessed over 200 iterations of Monte Carlo Cross-Validation using Accuracy, Precision, Recall, Fl-score, and ROC-AUC.
The results suggest that imbalance-handling strategies can materially affect predictive performance, particularly recall. Because the outcome of interest is death within …
Variance Shrinkage In Dunnett-Type Multiple Comparisons With Missing Data, Md Habibullah
Variance Shrinkage In Dunnett-Type Multiple Comparisons With Missing Data, Md Habibullah
UNF Graduate Theses and Dissertations
Dunnett’s procedure is widely used for comparing multiple treatments with a control, but its application becomes challenging in the presence of missing data and multiple com- parisons. An improved Dunnett-type procedure addresses this by using multiple imputation under Rubin’s framework and constructing unified confidence intervals based on a multi- variate t distribution, allowing valid simultaneous inference while controlling the family-wise error rate (FWER). This work further extends the method by incorporating shrinkage-based variance estimation. Specifically, individual group variances are shrunk toward a common value to improve stability. This approach is particularly effective when group variances are similar or moderately different, …
Ridit-Based Adaptive Allocation In Two-Stage Clinical Trials With Binary Outcomes, Dewan Fahim
Ridit-Based Adaptive Allocation In Two-Stage Clinical Trials With Binary Outcomes, Dewan Fahim
UNF Graduate Theses and Dissertations
This study explores better ways to assign patients to treatments in clinical trials with binary outcomes, such as success or failure. Adaptive methods are used to learn from early results and adjust treatment assignments during the trial, helping more patients receive better performing treatments while maintaining reliable conclusions. We focus on trials comparing multiple treatments using a two-stage design. In the first stage, several treatments are tested to identify the most promising one; in the second stage, that treatment is compared with a control. Unlike traditional equal assignment, we use adaptive allocation in the second stage to make better use …
A Comparative Study Of Classification Methods For Healthcare Analytics, Xueting Zhao
A Comparative Study Of Classification Methods For Healthcare Analytics, Xueting Zhao
UNF Graduate Theses and Dissertations
This thesis presents a comparative study of logistic regression, Linear Discriminant Analy- sis (LDA), and Quadratic Discriminant Analysis (QDA) for binary classification in healthcare analytics, integrating theoretical derivation, simulation, and real-data application. A facto- rial simulation study crosses the covariance structure (equal vs. unequal), predictor correla- tion (ρ ∈ {0, 0.5, 0.9}), dimensionality (p ∈ {2, 5, 10}) and sample size (n ∈ {50, 100, 200}) across 54 scenarios with 1,000 Monte Carlo replicates each. Three main findings emerge. Logistic regression and LDA are nearly interchangeable when the assumption of equal-covariance holds. QDA achieves substantially better discrimi- nation when class-specific …