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Paleoparasitological Studies On Mummies Of The Joseon Dynasty, Korea, Min Seo, Adauto Araújo, Karl J. Reinhard, Jong Yil Chai, Dong Hoon Shin

Karl Reinhard Publications

Paleoparasitology is the application of conventional or molecular investigative techniques to archeological samples in order to reveal parasitic infection patterns among past populations. Although pioneering studies already have reported key paleoparasitological findings around the world, the same sorts of studies had not, until very recently, been conducted in sufficient numbers in Korea. Mummified remains of individuals dating to the Korean Joseon Dynasty actually have proved very meaningful to concerned researchers, owing particularly to their superb preservation status, which makes them ideal subjects for paleoparasitological studies. Over the past several years, our study series on Korean mummies has yielded very pertinent …

Urinary Estrogen Metabolites And Self-Reported Infertility In Women Infected With Schistosoma Haematobium, Julio Santos, Maria Joao Gouveia, Nuno Vale, Maria De Lurdes Delgado, Ana Goncalves, Gabriel Rinaldi, Paul J. Brindley, +10 Additional Authors

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Background

Schistosomiasis is a neglected tropical disease, endemic in 76 countries, that afflicts more than 240 million people. The impact of schistosomiasis on infertility may be underestimated according to recent literature. Extracts of Schistosoma haematobium include estrogen-like metabolites termed catechol-estrogens that down regulate estrogen receptors alpha and beta in estrogen responsive cells. In addition, schistosome derived catechol-estrogens induce genotoxicity that result in estrogen-DNA adducts. These catechol estrogens and the catechol-estrogen-DNA adducts can be isolated from sera of people infected with S. haematobium. The aim of this study was to study infertility in females infected with S. haematobium and its …

Gut Helminths Of Two Species Of Light Geese In Illinois, Evan C. Boone

Undergraduate Honors Theses

Parasite burdens in lesser snow geese (Chen caerulescens caerulescens) and Ross’s geese (Chen rossii) migrating through central Illinois were determined and compared to documented parasite burdens on the breeding grounds in northern Canada and the wintering grounds in southern Texas. The digestive tracts of 48 snow geese (38 lesser snow geese and 10 Ross’s geese) were collected from 4 February to 3 March, 2012, in Raymond, Illinois. Eight helminth taxa (two species of Trematoda, four species of Nematoda, and two species of Cestoda) were recovered. Five of the eight helminth taxa were common in both species …

Suppression Of Basophil Histamine-Release And Other Ige-Dependent Responses In Childhood Schistosoma Mansoni Hookworm Co-Infection, Angela Pinot De Moira, Colin M. Fitzsimmons, Frances M. Jones, Shona Wilson, Pierre Cahen, Edridah Tukahebwa, Harriet Mpairwe, Joseph K. Mwatha, Jeffrey M. Bethony, Per S. Skov, Narcis B. Kabatereine, David W. Dunne

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Background. The poor correlation between allergen-specific-IgE (asIgE) and clinical signs of allergy in helminth infected populations suggests that helminth infections could protect against allergy by uncoupling asIgE from its effector mechanisms. We investigated this hypothesis in Ugandan schoolchildren coinfected with Schistosoma mansoni and hookworm.

Methods. Skin prick test (SPT) sensitivity to house dust mite allergen (HDM) and current wheeze were assessed pre-anthelmintic treatment. Non-specific (anti-IgE), helminth-specific and HDM-allergen-specific basophil histamine release (HR), plus helminth- and HDM-specific IgE and IgG4 responses were measured pre- and post-treatment.

Results. Non-specific- and helminth-specific-HR, and associations between helminth-specific-IgE and helminth-specific-HR increased post-treatment. Hookworm infection appeared …

Genetic And Morphological Diversity Of Trisetacus Species (Eriophyoidea: Phytoptidae) Associated With Coniferous Trees In Poland: Phylogeny, Barcoding, Host And Habitat Specialization, Mariusz Lewandowski, Anna Skoracka, Wiktoria Szydło, Marcin Kozak, Tobiasz Druciarek, Don A. Griffiths

Harold W. Manter Laboratory of Parasitology: Library Materials

Eriophyoid species belonging to the genus Trisetacus are economically important as pests of conifers. A narrow host specialization to conifers and some unique morphological characteristics have made these mites interesting subjects for scientific inquiry. In this study, we assessed morphological and genetic variation of seven Trisetacus species originating from six coniferous hosts in Poland by morphometric analysis and molecular sequencing of the mitochondrial cytochrome oxidase subunit I gene and the nuclear D2 region of 28S rDNA. The results confirmed the monophyly of the genus Trisetacus as well as the monophyly of five of the seven species studied. Both DNA sequences …

Histopathologic Aspects In Plagioscion Squamosissimus (Heckel, 1940) Induced By Neoechinorhynchus Veropesoi, Metacestodes And Anisakidae Juveniles = Aspectos Histopatólogicos Em Plagioscion Squamosissimus Induzidos Por Neoechinorhynchus Veropesoi, Metacestódeos E Juvenis Da Família Anisakidae, Francisco Tiago De Vasconcelos Melo, Rogério Antonio Ribeiro Rodrigues, Elane Guerreiro Giese, Scott Lyell Gardner, Jeannie Nascimento Dos Santos

Scott L. Gardner Publications

Abstract

Plagioscion squamosissimus (Heckel 1840), a fish endemic to the Amazon Basin and commonly known as the “silver croaker,” plays an important role in the ecology and economy of Pará State, Brazil. Knowledge of host-parasite relationships is important to understanding the role of parasites in the control of natural host populations. This work describes histopathological aspects caused by several common intestinal parasites found during a helminthological survey of fish in northern Brazil. We observed a high prevalence of helminth infection, especially by J₃ nematode juveniles of the family Anisakidae and metacestodes of the family Protocephalidae (both with 100% prevalence). …

Pathogenic Mechanisms And Signaling Pathways In Plasmodium Falciparum, Jennifer L. Sedillo

USF Tampa Graduate Theses and Dissertations

Plasmodium falciparum is a human intracellular parasite that is the causative agent of a deadly form of malaria. This species alone is responsible for 200 million cases of malaria annually resulting in over 1 million deaths worldwide. The excessive mortality due to P. falciparum infection is due to its ability to cause severe pathogenesis through hyperparasitemia and cytoadherence defined as the ability of infected red blood cells to adhere to host vasculature. Cytoadherence is mediated through the export of parasite proteins to the surface of the infected red blood cell (RBC). Exported proteins have been identified but the pathway for …

An Immunomics Approach To Schistosome Antigen Discovery: Antibody Signatures Of Naturally Resistant And Chronically Infected Individuals From Endemic Areas, Soraya Gaze, Patrick Driguez, Mark S. Pearson, Tiago Mendes, Denise L. Doolan, Jeffrey M. Bethony, +14 Additional Authors

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Schistosomiasis is a neglected tropical disease that is responsible for almost 300,000 deaths annually. Mass drug administration (MDA) is used worldwide for the control of schistosomiasis, but chemotherapy fails to prevent reinfection with schistosomes, so MDA alone is not sufficient to eliminate the disease, and a prophylactic vaccine is required. Herein, we take advantage of recent advances in systems biology and longitudinal studies in schistosomiasis endemic areas in Brazil to pilot an immunomics approach to the discovery of schistosomiasis vaccine antigens. We selected mostly surface-derived proteins, produced them using an in vitro rapid translation system and then printed them to …

Molecular Evidence For Vector Implication Of Onchocerca Lupi In Los Angeles County, Ca, Shanna June Bolcen

USF Tampa Graduate Theses and Dissertations

Onchocerca is a genus of roundworm most commonly associated with the human infection onchocerciasis, or river blindness. While typically a zoonotic infection of ungulate populations, canine cases (Onchocerca lupi) have been identified in the United States and Greece. In 2012, Los Angeles County, Veterinary Public Health Program identified 3 cases of Onchocerca spp. infections in domestic canines. Samples from the ensuing blackfly collections were sent to the Global Health Infectious Disease Research Unnasch Laboratory for parasite isolation and vector species identification. Species-specific primers were designed and optimized for O. lupi using a non- specific cytochrome oxidase (COI) gene target (689bp) …

Hymenolepis Robertrauschi N. Sp. From Grasshopper Mice Onychomys Spp. In New Mexico And Nebraska, U.S.A., Scott Lyell Gardner, Brent A. Luedders, Donald W. Duszynski

Harold W. Manter Laboratory of Parasitology: Faculty Publications

From 1989 through 1998, a total of 358 grasshopper mice were collected and examined for helminth and protistan parasites from several habitat types on the Sevilleta Long Term Ecological Research (LTER) site in New Mexico, U.S.A. Of these, 205 individuals were identified as Onychomys leucogaster (Wied-Neuwied 1841) and 153 individuals were classified as O. arenicola Mearns 1896. Many individuals of Onychomys were infected with a new species of Hymenolepididae (Hymenolepis robertrauschi), which is herein described, illustrated, and compared with all species of Nearctic Hymenolepis s. str. Hymenolepis robertrauschi was found in 26% of the individuals of O. arenicola …

Chagas Disease In The 21st Century: A Public Health Success Or An Emerging Threat?, Kevin M. Bonney

Publications and Research

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major public health burden in Latin America and a potentially serious emerging threat to a number of countries throughout the world. Although public health programs have significantly reduced the prevalence of Chagas disease in Latin America in recent decades, the number of infections in the United States and non-endemic countries in Europe and the Western Pacific Region continues to rise. Moreover, there is still no vaccine or highly effective cure available for the approximately 10 million people currently infected with T. cruzi, a third of which will develop potentially …

Genome Of The Human Hookworm Necator Americanus, Yat T. Tang, Xin Gao, Bruce A. Rosa, Sahar Abubucker, Kymberlie Hallsworth-Pepin, Peter J. Hotez, Jeffrey M. Bethony, +23 Additional Authors

Microbiology, Immunology, and Tropical Medicine Faculty Publications

The hookworm Necator americanus is the predominant soil-transmitted human parasite. Adult worms feed on blood in the small intestine, causing iron-deficiency anemia, malnutrition, growth and development stunting in children, and severe morbidity and mortality during pregnancy in women. We report sequencing and assembly of the N. americanus genome (244 Mb, 19,151 genes). Characterization of this first hookworm genome sequence identified genes orchestrating the hookworm's invasion of the human host, genes involved in blood feeding and development, and genes encoding proteins that represent new potential drug targets against hookworms. N. americanus has undergone a considerable and unique expansion of immunomodulator proteins, …

Phages Of Non-Diary Lactococci: Isolation And Characterization Of Phi L47, A Phage Infecting The Grass Isolate Lactococcus Lactis Ssp Cremoris Dpc6860, Daniel Cavanagh, Caitríona M. Guinane, Horst Neve, Aidan Coffey, R. Paul Ross, Gerald F. Fitzgerald, Olivia Mcauliffe

Department of Biological Sciences Publications

Lactococci isolated from non-dairy sources have been found to possess enhanced metabolic activity when compared to dairy strains. These capabilities may be harnessed through the use of these strains as starter or adjunct cultures to produce more diverse flavor profiles in cheese and other dairy products. To understand the interactions between these organisms and the phages that infect them, a number of phages were isolated against lactococcal strains of non-dairy origin. One such phage, ΦL47, was isolated from a sewage sample using the grass isolate L. lactis ssp. cremoris DPC6860 as a host. Visualization of phage virions by transmission electron …

Suppression Of Aquaporin, A Mediator Of Water Channel Control In The Carcinogenic Liver Fluke, Opisthorchis Viverrini, Sirikanda Thanasuwan, Supawadee Piratae, Paul J. Brindley, Alex Loukas, Sasithorn Kaewkes, Thewarach Laha

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Background

Opisthorchiasis and Opisthorchis viverrini-associated bile duct cancer represent major public health threats in Thailand and Laos. The tegument of this food borne fluke plays pivotal roles in parasite metabolism, homeostasis and osmoregulation. Excretory/secretory products also pass from the fluke to the biliary environment, products that likely underlie pathogenesis of liver fluke infection. Aquaporins (AQPs), belong to the major intrinsic protein superfamily of integral plasma membrane channel proteins that selectively transport water across cell membranes. AQPs play key roles as water and ion transport channels through the tegument of helminth parasites.

Methods

Here, two forms of AQP mRNAs from the …

Schistosomes And Snails: A Molecular Encounter, Matty Knight, Halime D. Arican-Goktas, Wannaporn Ittiprasert, Edwin C. Odoemelam, Andre N. Miller, Joanna M. Bridger

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Biomphalaria glabrata snails play an integral role in the transmission of Schistosoma mansoni, the causative agent for human schistosomiasis in the Western hemisphere. For the past two decades, tremendous advances have been made in research aimed at elucidating the molecular basis of the snail/parasite interaction. The growing concern that there is no vaccine to prevent schistosomiasis and only one effective drug in existence provides the impetus to develop new control strategies based on eliminating schistosomes at the snail-stage of the life cycle. To elucidate why a given snail is not always compatible to each and every schistosome it encounters, B. …

Schistosome And Liver Fluke Derived Catechol-Estrogens And Helminth Associated Cancers., José M. Correia Da Costa, Nuno Vale, Maria J. Gouveia, Mónica C. Botelho, Banchob Sripa, Lúcio L. Santos, Júlio H. Santos, Gabriel Rinaldi, Paul J. Brindley

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Infection with helminth parasites remains a persistent public health problem in developing countries. Three of these pathogens, the liver flukes Clonorchis sinensis, Opisthorchis viverrini and the blood fluke Schistosoma haematobium, are of particular concern due to their classification as Group 1 carcinogens: infection with these worms is carcinogenic. Using liquid chromatography-mass spectrometry (LC-MS/MS) approaches, we identified steroid hormone like (e.g., oxysterol-like, catechol estrogen quinone-like, etc.) metabolites and related DNA-adducts, apparently of parasite origin, in developmental stages including eggs of S. haematobium, in urine of people with urogenital schistosomiasis, and in the adult stage of O. viverrini. Since these kinds of …

Helminth.Net: Expansions To Nematode.Net And An Introduction To Trematode.Net, John Martin, Bruce A. Rosa, Philip Ozersky, Kymberlie Hallsworth-Pepin, Xu Zhang, Veena Bhonagiri-Palsikar, Rahul Tyagi, Qi Wang, Young-Jun Choi, Xin Gao, Samantha N. Mcnulty, Paul J. Brindley, Makedonka Mitreva

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Helminth.net (http://www.helminth.net) is the new moniker for a collection of databases: Nematode.net and Trematode.net. Within this collection we provide services and resources for parasitic roundworms (nematodes) and flatworms (trematodes), collectively known as helminths. For over a decade we have provided resources for studying nematodes via our veteran site Nematode.net (http://nematode.net). In this article, (i) we provide an update on the expansions of Nematode.net that hosts omics data from 84 species and provides advanced search tools to the broad scientific community so that data can be mined in a useful and user-friendly manner and (ii) we …

Resurrection And Redescription Of Varestrongylus Alces (Nematoda: Protostrongylidae), A Lungworm Of The Eurasian Moose (Alces Alces), With Report On Associated Pathology, Guilherme G. Verocai, Eric P. Hoberg, Turid Vikøren, Kjell Handeland, Bjørnar Ytrehus, Andrew M. Rezansoff, Rebecca K. Davidson, John S. Gilleard, Susan J. Kutz

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Background: Varestrongylus alces, a lungworm in Eurasian moose from Europe has been considered a junior synonym of Varestrongylus capreoli, in European roe deer, due to a poorly detailed morphological description and the absence of a type-series.

Methods: Specimens used in the redescription were collected from lesions in the lungs of Eurasian moose, from Vestby, Norway. Specimens were described based on comparative morphology and integrated approaches. Molecular identification was based on PCR, cloning and sequencing of the ITS-2 region of the nuclear ribosomal DNA. Phylogenetic analysis compared V. alces ITS-2 sequences to these of other Varestrongylus species …

Modulation Of Vaccine-Induced Responses By Anthelmintic Treatment In Ponies, Emily Rubinson

Theses and Dissertations--Medical Sciences

Vaccines and anthelmintics induce an inflammatory response in equids. Since they are commonly given concurrently, it is practical to study any interaction between them. This study evaluated whether IVM and PYR would modulate the acute phase inflammatory response, the systemic gene expression of pro-inflammatory cytokines, and vaccine-specific titers induced by WNV, EHV, and KLH vaccines. Naturally-infected, yearling ponies were sorted by gender, then fecal epgs. They were randomly assigned to three treatment groups: IVM, PYR, and control. All ponies received vaccinations intramuscularly on days 0 and 29. Whole blood, serum, and plasma samples were collected 1, 3, and 14 days …

Some Aspects Of The Biology Of Monogenean (Platyhelminth) Parasites Of Marine And Freshwater Fishes, Graham C. Kearn

Harold W. Manter Laboratory of Parasitology: Library Materials

Müller was the first to describe a monogenean, collected from the skin of the halibut (Hippoglossus hippoglossus). However, he regarded the parasite as a leech and named it Hirudo hippoglossi. It was not until 1858 that its status as a monogenean was established by van Beneden and named Epibdella (now Entobdella) hippoglossi. Van Beneden published a detailed and accurate description of the parasite and one of his excellent illustrations is reproduced here. Entobdella hippoglossi is one of the largest monogeneans, measuring up to 2 cm in length. It has a smaller relative, measuring 5 to …

Pentastomids Of Wild Snakes In Australia, Crystal Kelehear, David M. Spratt, Denis O'Meally, Richard Shine

Harold W. Manter Laboratory of Parasitology: Library Materials

Pentastomids are endoparasites of the respiratory system of vertebrates, maturing primarily in carnivorous reptiles. Adult and larval pentastomids can cause severe pathology resulting in the death of their intermediate and definitive hosts. The study of pentastomids is a neglected field, impaired by risk of zoonoses, difficulties in species identification, and life cycle complexities. We surveyed wild snakes in the tropics of Australia to clarify which host species possess these parasites, and then sought to identify these pentastomids using a combination of morphological and molecular techniques. We detected pentastomid infections in 59% of the 81 snakes surveyed. The ubiquity of pentastomid …

Seussapex, A New Genus Of Lecanicephalidean Tapeworm (Platyhelminthes: Cestoda) From The Stingray Genus Himantura (Myliobatiformes: Dasyatidae) In The Indo-West Pacific With Investigation Of Mode Of Attachment, Kirsten Jensen, Shelbi L. Russell

Harold W. Manter Laboratory of Parasitology: Library Materials

A new lecanicephalidean genus, Seussapex gen. n., is erected for specimens collected from stingrays from the Indo-West Pacific resembling the little known species Tenia [sic] narinari MacCallum, 1917 from the spotted eagle ray, Aetobatus narinari (Euphrasen). Members of this new genus are unique in their possession of a multi-tiered apical structure comprising a bipartite apical modification of the scolex proper, and an externally bipartite apical organ with anterior and posterior glandular compartments internally. The appearance of the scolex varies dramatically depending on state of protrusion and/or evagination of these different parts which appear to be able to function independently. Seussapex …

Announcement: Transfer Of The U. S. National Parasite Collection, Eric P. Hoberg, Anna J. Phillips

Harold W. Manter Laboratory of Parasitology: Library Materials

In 2013 an agreement was articulated between the United States Department of Agriculture, Agricultural Research Service (USDA/ARS) and the Smithsonian Institution to transfer the United States National Parasite Collection (USNPC) in its entirety (fluid specimens, slide specimens, frozen tissues and reprints) to the National Museum of Natural History (NMNH) in Washington, DC. Current collections staff, including senior curator Dr. Eric P. Hoberg and support scientists/managers from the ARS will be transferred with the collection and with adjunct appointments in the NMNH will provide continuity and assistance for curation and accessibility during and after the relocation. New curatorial controls will be …

On The Helminth Fauna Of Small Mammals In Hustai National Park, Mongolia, Sumiya Ganzorig, Nyamsuren Batsaikhan, Katsuro Hagiwara, Scott Lyell Gardner, Kenji Baba, Buho Hoshino

Scott L. Gardner Publications

Introduction

The Hustai National Park is one of the special protected areas in Mongolia. The park is famous by the successful re-introduction of the wild horse (takhi), and its well-managed protection work. The park has a rich and diverse mammal fauna and flora. Of these, the takhi, and other large mammal species are objects of intensive research by the international researchers, but the parasitic helminth fauna in Hustai National Park is remained unknown. Species diversity of wildlife and its abundance, especially high density of both the prey and predators, might allow the presence of various parasitic and symbiotic organisms on …

Why American Higher Education Needs Parasitologists, John J. Janovy Jr.

John J. Janovy, Jr. Publications

Addresses four topics that characterize the discipline of parasitology and are largely missing from our national conversation in the United States about education, especially at the college and university level. Those topics are the production of transferable skills; our perceptions of the world, especially the natural world; access to reasonably difficult problems in natural settings; and intellectual epidemiology, or the movement of ideas, innovations, and cultural items through populations. These topics have been a part of the author's discussions with fellow parasitologists for at least half a century, beginning with his choice to pursue a graduate degree under the supervision …

Redescription Of Oligacanthorhynchus Microcephalus (Rudolphi, 1819) Schmidt 1972 (Syn. Oligacanthorhynchus Tortuosa (Leidy, 1850) Schmidt 1972) (Acanthocephala: Oligacanthorhynchidae), Dennis J. Richardson, Scott Lyell Gardner, Jonathan W. Allen Jr.

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Oligacanthorhynchus microcephalus (Rudolphi, 1819) Schmidt, 1972 was originally described from the philander opossum Caluromys philander from Brazil. Oligacanthorhynchus tortuosa (Leidy, 1850) Schmidt, 1972 was originally described from the Virginia opossum (Didelphis virginiana) in North America. Six years after describing O. tortuosa, Leidy indicated the synonomy of O. tortuosa with O. microcephalus. This taxonomic view persisted for decades until Van Cleave, in 1924, recognized the validity of O. tortuosa, apparently without examining the type material of O. microcephalus. Subsequent workers have recognized two species of Oligacanthorhynchus from New World opossums: O. microcephalus from South American …

Varestrongylus Eleguneniensis Sp. N. (Nematoda: Protostrongylidae): A Widespread, Multi-Host Lungworm Of Wild North American Ungulates, With An Emended Diagnosis For The Genus And Explorations Of Biogeography, Guilherme G. Verocai, Susan J. Kutz, Manon Simard, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Background: A putative new species of Varestrongylus has been recently recognized in wild North American ungulates based on the ITS-2 sequences of larvae isolated from feces during a wide geographic survey. No taxonomic description was provided, as adult specimens were not examined. Methods: Lungworm specimens were collected in the terminal bronchioles of muskoxen from Quebec, and a woodland caribou from central Alberta, Canada. The L3 stage was recovered from experimentally infected slugs (Deroceras spp.). Description of specimens was based on comparative morphology and integrated approaches. Molecular identity was determined by PCR and sequencing of the ITS-2 region of …

Air Sac Nematode Monopetalonema Alcedinis In A Belted Kingfisher (Megaceryle Alcyon) In Maryland, Usa, Ellen Bronson, Kathleen Kelly, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Sporadic and geographically widespread reports of parasites affecting the Belted Kingfisher (Megaceryle alcyon) have been published but few have described details of the pathology. A female, adult kingfisher was found dead in a heavily wooded area of a zoo in Maryland, USA. At necropsy, numerous sexually dimorphic, 4.4–40.5-cm adult Monopetalonema alcedinis nematodes were found tightly wound within the coelomic cavity between organs and completely filling the caudal thoracic and abdominal air sacs. Abundant, 30–60-mm diameter, larvated, thick-walled ova were found in the bronchi and parabronchi, within the mesentery, and in the serosa of multiple coelomic organs. Monopetalonema alcedinis …

In Memoriam: Robert Lloyd Rausch—A Life In Nature And Field Biology, 1921–2012, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

During his distinguished career, Robert Rausch, a man of great integrity and principles, served in his lifetime as a singular ambassador for parasitology in a broad international arena. Robert was a friend to many, was honored to be considered an equal among the nomadic bands of Nunamiut traversing the Brooks Range 60 years ago, and will be long remembered for the strength of his science and his perceptive views of the natural world.

Finding Them Before They Find Us: Informatics, Parasites, And Environments In Accelerating Climate Change, Daniel R. Brooks, Eric P. Hoberg, Walter A. Boeger, Scott Lyell Gardner, Kurt E. Galbreath, David Herczeg, Hugo H. Mejía-Madrid, S. Elizabeth Rácz, Altangerel Tsogtsaikhan Dursahinhan

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Parasites are agents of disease in humans, livestock, crops, and wildlife and are powerful representations of the ecological and historical context of the diseases they cause. Recognizing a nexus of professional opportunities and global public need, we gathered at the Cedar Point Biological Station of the University of Nebraska in September 2012 to formulate a cooperative and broad platform for providing essential information about the evolution, ecology, and epidemiology of parasites across host groups, parasite groups, geographical regions, and ecosystem types. A general protocol, documentation–assessment–monitoring–action (DAMA), suggests an integrated proposal to build a proactive capacity to understand, anticipate, and respond …