Digital Commons Network^™

Multidisciplinary Survivorship Care, Sue N. Gardner Rn, Msn, Crnp, Aocnp, Gregory Harper Md, Phd, Dorothy Morrone Rnc, Ms, Ocn, Jennifer Brennan Rd, Cso, Andrea Geshan Rn, Msw, Diane Brong Lcsw, Jennifer Roeder Mspt, Mba

Department of Medicine

No abstract provided.

Effect Of Exogenous Leptin On Thrombotic And Metabolic Profiles Of Fvb/B6 Lipodystrophic Mice, Hoda Chaouki Kadouh

Wayne State University Theses

Lipodystrophy caused by fat deficiency contributes to metabolic disease for which several treatment modalities have been implemented, with leptin therapy being the most effective to date. In addition to playing a role in energy homeostasis and metabolism, leptin was also shown to play a pro-thrombotic role in mice. This role was not examined in fatless mice, neither was thrombosis measured. The AZIP/F-1 (FVB) lipodystrophic mouse appeared to have a prolonged arterial occlusion time (p〈0.05) in a trial done in our lab, with clotting factors being normal. The present study was designed to observe the thrombotic and metabolic characteristics of fatless …

Beliefs And Attitudes Toward Vegetarian Lifestyle Across Generations, Peter Pribis, Rose C. Pencak, Tevni Grajales

Faculty Publications

The objective of the study was to examine whether reasons to adopt vegetarian lifestyle differ significantly among generations. Using a Food Frequency Questionnaire (FFQ), we identified that 4% of the participants were vegans, 25% lacto-ovo-vegetarians, 4% pesco-vegetarians and 67% non-vegetarian. Younger people significantly agreed more with the moral reason and with the environmental reason. People ages 41-60 significantly agreed more with the health reason. There are significant differences across generations as to why people choose to live a vegetarian lifestyle. © 2010 by the authors; licensee MDPI, Basel, Switzerland.

Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 11 2010, Several Authors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Cardiovascular Disease Risk Factors And Associations With Indicators Of Body Fat, Diet, And Physical Activity In U.S. Children Ages 6–11, Melissa A. Masters

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Research was conducted to determine the prevalence of cardiovascular disease risk factors in U.S. children ages 6-11 and associations with body fat, diet, and physical activity. Data for 685 children ages 6-11 was obtained from the National Health and Nutrition Examination Survey (NHANES). NHANES data was examined to determine the prevalence of cardiovascular disease risk factors in these children, the impact of indicators of body fat on cardiovascular disease risk factors, the association between cardiovascular disease risk factors and dietary components, and the relationship between physical activity and cardiovascular disease risk factors among U.S. children. Children were also evaluated for …

Protection Against Endothelial Inflammation By Green Tea Flavonoids, Yuanyuan Zheng

University of Kentucky Doctoral Dissertations

Endothelial inflammation is a pivotal early event in the development of atherosclerosis. Long term exposure to cardiovascular risk factors will ultimately exhaust those protective anti-inflammatory factors such as the heme oxygenase (HO) system. The HO system plays a critical role in cellular and tissue self-defense against oxidative stress and inflammation. Caveolae are membrane domains and are particularly abundant in endothelial cells, where they are believed to play a major role in the regulation of endothelial vesicular trafficking as well as the uptake of lipids and related lipophilic compounds, possibly including bioactive food components such as flavonoids. Research in this dissertation …

Effectiveness Of Weight Control Through Weight Watch Programs, V. A. Black, P. Boumtje

Journal of the Arkansas Academy of Science

Linear probability estimation and survey data are employed to quantify the influence of the lifestyles of individuals on the change in their body mass index (BMI). The analysis also explores the effects of demographic characteristics (age, gender, and ethnicity) in weight management. Results suggest evidence of association between changes in lifestyle and changes in the BMI of individuals.

The Effect Of Heating On The Antioxidants Content In Edible Oil., Premanand Krishnan

Student Works (2010-2019)

There are many types edible oils with various brand found in the market. The types of oils involved in the analysis for the antioxidants content were palm oil, olive oil, canola oil, sunflower oil, soy bean oil, corn oil, gingerly oil, rice bran oil, mixed oil and ayurvedic oil. The method used to evaluate the amount antioxidants in this study was 2, 2-diphenyl-1-picrylhydrazyl (DPPH). In this test, the scavenging of the DPPH radicals was followed by monitoring the decrease in absorbance at 515 nm. Heating the oil samples to various temperatures shows negative effect on the antioxidants content. The antioxidants …

Liver Injury In Acute Fatty Liver Of Pregnancy: Possible Link To Placental Mitochondrial Dysfunction And Oxidative Stress, Sathish Kumar Natarajan, Kavitha R. Thangaraj, C. E. Eapen, Anup Ramachandran, Ashis Mukhopadhya, Mathews Mathai, Lakshmi Seshadri, Abraham Peedikayil, Banumathi Ramakrishna, Kunnissery A. Balasubramanian

Department of Nutrition and Health Sciences: Faculty Publications

Acute fatty liver of pregnancy (AFLP) is a rare disorder which is fatal if not recognized and treated early. Delivery of the feto-placental unit results in dramatic improvement in maternal liver function, suggesting a role for the placenta. However, the mechanisms by which defects in the fetus or placenta lead to maternal liver damage are not well understood and form the focus of this study. Placenta and serum were obtained at delivery from patients with AFLP, and placental mitochondria and peroxisomes were isolated. Placental mitochondrial function, oxidative stress, and fatty acid composition as well asserumantioxidants, oxidativeandnitrosative stress markers,andfatty acid analysis …

Current Perceptions Regarding The Importance And Safety Of Fish Consumption And Omega-3 Fatty Acid Supplementation Among Pregnant Women, Jessica L. Ess

Master's Theses and Doctoral Dissertations

Background: Previous studies suggest many pregnant women are under-consuming fatty fish and are deficient in omega-3 (ω-3) fatty acids.

Background: Previous studies suggest many pregnant women are under-consuming fatty fish and are deficient in omega-3 (ω-3) fatty acids.

Methods: A 10-question survey distributed to expectant mothers via an online survey and via paper form through 3 obstetric clinics over a 2-month period.

Results: Of the 104 participants, 82% consumed less than 2-3 servings of fish per week, and at least 30% were confused about mercury content. Over 60% of doctors did not provide recommendations regarding ω-3 intake. One-third of participants …

Fruit And Vegetable Consumption In Four Elementary Schools After Implementation Of Nutrition Education Programs, Lori Nelson

Master's Theses and Doctoral Dissertations

Nutrition education programs in schools often promote fruits and vegetables with the goal of increasing consumption among children. This study determined whether nutrition education programs increased fruit and vegetable intake in four elementary schools in Florida from October 2008 to October 2009. School A offered the U.S.D.A. Fresh Fruit & Vegetable Program; School B had a Student Wellness Advisory Council, OrganWise Guys and CATCH; School C had OrganWise Guys and CATCH; School D had no nutrition education programs. Students’ favorite fruits and vegetables at breakfast and lunch were compiled. An increase in fruit intake was observed in three out of …

Health Impact Of Brief Interventions By A Registered Dietitian During Exercise Sessions In A Phase 2 Cardiac Rehabilitation Setting, Terrie Holewinski

Master's Theses and Doctoral Dissertations

Weight management is integral to cardiovascular risk reduction. However, minimal weight loss is achieved during participation in many cardiac rehabilitation (CR) programs. The objective of the present study was to establish if brief interventions by a registered dietitian (RD) during cardiac rehabilitation sessions improved the health status of patients with cardiovascular disease. An RD provided individualized nutrition counseling, answered nutrition questions, and reviewed weekly progress in a CR program for a four-month period. At baseline and upon completion of 19 CR sessions, nutrition knowledge was assessed using a 38-question test, and body weight was measured. Upon completing CR, patients rated …

Targeted Deletion Of Hepatocyte Abca1 Leads To Very Low Density Lipoprotein Triglyceride Overproduction And Low Density Lipoprotein Hypercatabolism, Soonkyu Chung, Jenelle M. Timmins, Myngan Duong, Chiara Degirolamo, Shunxing Rong, Janet K. Sawyer, Roshni R. Singaraja, Michael R. Hayden, Nobuyo Maeda, Lawrence L. Rudel, Gregory S. Shelness, John S. Parks

Department of Nutrition and Health Sciences: Faculty Publications

Loss of ABCA1 activity in Tangier disease (TD) is associated with abnormal apoB lipoprotein (Lp) metabolism in addition to the complete absence of high density lipoprotein (HDL). We used hepatocyte-specific ABCA1 knock-out (HSKO) mice to test the hypothesis that hepatic ABCA1 plays dual roles in regulating Lp metabolism and nascent HDL formation. HSKO mice recapitulated the TD lipid phenotype with postprandial hypertriglyceridemia, markedly decreased LDL, and near absence of HDL. Triglyceride (TG) secretion was 2-fold higher in HSKO compared with wild type mice, primarily due to secretion of larger TG-enriched VLDL secondary to reduced hepatic phosphatidylinositol 3-kinase signaling. HSKO mice …

Nutrition-Related Practices And Attitudes Of Kansas Skipped-Generation(S) Caregivers And Their Grandchildren, Mary Meck Higgins, Bethany J. Murray

Department of Nutrition and Health Sciences: Faculty Publications

Despite growing numbers, the nutrition practices and attitudes of skipped-generation(s) kinship caregivers regarding feeding the dependent children in their care have not been examined. In this qualitative study, transcriptions of semi-structured interviews with 19 female and four male skipped-generation(s) Kansas caregivers (ages 47 to 80, 92% non-Hispanic whites, 83% female, 78% grandparents and 22% great-aunt or great-grandparent caregivers; caring for a range of one to four children, ages three to 18, for an average of nine years) were content analyzed for how their nutrition-related practices and attitudes had changed since parenting the first time. Sub-themes regarding practices included: being more …

Predicting Successful Aging In A Population-Based Sample Of Georgia Centenarians, Jonathan Arnold, Jianliang Dai, Lusine Nahapetyan, Ankit Arte, Mary Ann Johnson, Dorothy Hausman, Willard L. Rodgers, Robert Hensley, Peter Martin, Maurice Macdonald, Adam Davey, Ilene C. Siegler, S. Michal Jazwinski, Leonard W. Poon

Department of Nutrition and Health Sciences: Faculty Publications

Used a population-based sample (Georgia Centenarian Study, GCS), to determine proportions of centenarians reaching 100 years as (1) survivors (43%) of chronic diseases first experienced between 0–80 years of age, (2) delayers (36%) with chronic diseases first experienced between 80–98 years of age, or (3) escapers (17%) with chronic diseases only at 98 years of age or older. Diseases fall into two morbidity profiles of 11 chronic diseases; one including cardiovascular disease, cancer, anemia, and osteoporosis, and another including dementia. Centenarians at risk for cancer in their lifetime tended to be escapers (73%), while those at risk for cardiovascular disease …

Dvd Multimedia Nutrition Education Curriculum For Self-Study, J. Tawzer, Heidi Leblanc, Nedra K. Christensen, Janet Anderson, Jennie Murri

Nutrition, Dietetics, and Food Sciences Faculty Publications

The State of Utah has one of the highest food insecurity rates in the nation. It is ranked in the top 4% in the nation of being food insecure and 34% of the state is considered low-income, defined as at or below 185% of poverty level (LeBlanc, Christofferson, & Christensen, 2008). These trends place Utah’s low-income population at increased risk of obesity and chronic disease. The Center of Hunger and Poverty reported a high rate of obesity among low-income individuals, with hunger, poverty, and obesity frequently occurring at the same time (USDA, 2009). With limited income, quantity is often more …

Endocrine Disruptors And Obesity: An Examination Of Selected Persistent Organic Pollutants In The Nhanes 1999-2002 Data, Mai A. Elobeid, Miguel A. Padilla, David W. Brock, Douglas M. Ruden, David B. Allison

Psychology Faculty Publications

Recent evidence suggests that endocrine disrupting chemicals (EDCs) may cause perturbations in endogenous hormonal regulation that predispose to weight gain. Using data from NHANES (1999-2002), we investigated the association between body mass index (BMI), waist circumference (WC) and selected persistent organic pollutants (POPs) via multiple linear regressions. Consistent interaction was found between gender, ln oxychlordane and ln p,p' DDT. Also, we found an association between WC and ln oxychlordane and ln hpcdd in subjects with detectable levels of POPs, whereas an association between WC and ln p,p' DDT was observed in all subjects. Furthermore, ln Ocdd showed an increase with …

Obesity And Food Choices Among Faculty And Staff At A Large Urban University, Marjorie Freedman, Rebecca Rubinstein

Faculty Publications

Objective: In order to address increasing health care costs associated with obesity, this study sought to determine prevalence of overweight and obesity and examine eating behaviors, food choices, health beliefs, and attitudes of university employees. Participants and Methods: An online survey was distributed to > 3,800 faculty and staff at a large public metropolitan university in Winter 2008. Results: Almost half (48%) of 806 respondents were classified as overweight or obese. Compared to those with normal weights, overweight and obese respondents consumed fewer fruits and vegetables (p < .05), were less confident in making healthful food choices (p < .001), and were more influenced by food choices available in on-campus dining facilities (p < .05). Conclusions: Obesity among university employees warrants attention. Because these employees have less self-efficacy and consume less healthful diets than their normal weight colleagues, universities need to improve on-campus access to healthful foods.

Development, Evaluation, And Validation Of Environmental Assessment Tools To Evaluate The College Nutrition Environment, Marjorie Freedman

Faculty Publications

Objective: To develop, evaluate, and validate 2 nutrition environment assessment tools (surveys), for specific use in combating overweight on college/university campuses.Participants and Methods: Invitations to complete surveys were e-mailed to food service and health center directors at 47 universities, Winter 2008. Overall response rate was 48%. Responses from the 39 individuals who completed tool evaluations at the end of each survey were analyzed. Follow-up interviews and site visits performed through Summer 2008 validated responses. Results: The majority of respondents (64%) indicated tools were effective at assessing their nutrition environments; 78% believed these types of assessment tools to be important to …

Sodexo Leading Environmental Change At Lehigh Valley Health Network, Andrew Barsky Cdm, Cfpp

Clinical Nutrition Service

No abstract provided.

Polychlorinated Biphenyl-Induced Endothelial Cell Dysfunction And Its Modulation By Dietary Lipids, Zuzana Majkova

University of Kentucky Doctoral Dissertations

Cardiovascular diseases are the number one cause of death in Western societies. Endothelial dysfunction is an early event in the pathology of atherosclerosis, which is an underlying cause in the majority of cardiovascular events. Exposure to persistent environmental pollutants, such as polychlorinated biphenyls (PCBs), is a risk factor for the development of atherosclerosis.

First, we tested a hypothesis that coplanar PCBs, dioxin-like chemicals with affinity for aryl hydrocarbon receptor (AhR), can stimulate up-regulation of monocyte chemoattractant protein-1 (MCP-1), an endothelium-derived chemokine that attracts monocytes into sub-endothelial space in early stages of atherosclerosis. Coplanar PCBs 77 and 126 increased expression of …

Survival And Inflammation In Patients With Heart Failure: The Impact Of Overweight, Obesity, Diabetes And Fruit And Vegetable Consumption, Heather Payne-Emerson

University of Kentucky Doctoral Dissertations

Overweight and obesity are paradoxically associated with better survival in patients with heart failure (HF). This association is poorly understood, in part because the impact of diabetes (DM) on survival of overweight and obese HF patients has not been considered. Inflammation may contribute to worse survival in overweight and obese HF patients with DM, and levels of inflammation may be associated with fruit and vegetable consumption. However, neither of these relationships has been investigated in patients with HF.

The purposes of this dissertation were to a) examine the effect of DM on survival of overweight and obese patients with HF, …

Role Of Group X Secretory Phospholipase A2 In Murine Adipocytes, Xia Li

University of Kentucky Doctoral Dissertations

The secretory phospholipase A₂ (sPLA₂) family is a group of enzymes that catalyze the hydrolysis of glycerophospholipids at the sn-2 position, generating free fatty acids and lysophospholipids. The sPLA₂ family has been implicated in various physiological and pathological activities. Eleven sPLA₂’s have been identified in mammals, and the function of each isoform likely reflects its tissue distribution and substrate specificity. Studies in vitro indicate that Group X (GX) sPLA₂ potently releases arachidonic acid (AA) and lysophosphatidylcholine from mammalian cell membranes. Interestingly, some of the biological effects mediated by GX sPLA₂ in vitro …

Penyebab Keberhasilan Dan Kegagalan Praktik Pemberian Asi Eksklusif, Sandra Fikawati, Ahmad Syafiq

Kesmas

Target cakupan ASI eksklusif oleh Depkes RI sebesar 80% masih sulit dilaksanakan. Berbagai studi menunjukkan cakupan ASI eksklusif di Indonesia masih sangat rendah. Ada berbagai faktor yang mempengaruhi keberhasilan dan kegagalan pelaksanaan ASI eksklusif. Penelitian ini bertujuan untuk menggali berbagai faktor predisposisi, pemungkin, dan pendorong yang berhubungan dengan keberhasilan atau kegagalan pelaksanaan ASI eksklusif di Puskesmas Kecamatan Jagakarsa, Jakarta Selatan. Disain studi adalah studi kualitatif dengan 14 informan yaitu ibu bayi yang berusia >6-24 bulan yang dibagi berdasarkan keberhasilan pelaksanaan ASI eksklusifnya. Data dikumpulkan melalui wawancara mendalam dan dilakukan triangulasi sumber data mencakup bidan puskesmas dan suami serta triangulasi analisis …

Prevalence Of Childhood Obesity: A Study On Bowling Green, Ky Middle School Students, Emily Jensen

Masters Theses & Specialist Projects

No abstract provided.

Computational Prediction Of The Agregated Structure Of Denatured Lysozyme, Pongsathorn Chotikasemsri

Masters Theses & Specialist Projects

Mis-folded proteins and their associated aggregates are a contributing factor in some human diseases. In this study we used the protein lysozyme as a model to define aggregation structures under denaturing conditions. Sasahara et al. (2007), Frare et al. (2009, 2006), and Rubin et al. (2008) observed conditions where heat denatured lysozyme formed fibril structures that were observed to be 8-17 nanometers in diameter under the electron microscope. Even though the crystal structure of lysozyme is known, the denatured form of this protein is still unknown. Therefore, we used Rosetta++ protein folding and blind docking software to create in silico …

Brain Food, Winston J. Craig

Lake Union Herald

No abstract provided.

The Malawi Project: From Conventional To Holistic Decision Making, Grace Wetmore

Animal Science

How the Cal Poly Malawi Appropriate Technologies Team, and other development groups, can use Holistic Management to aid developing countries in an effort towards a sustainable future.

School Breakfast Program: Efficacy And Impact, Amber Ward

Food Science and Nutrition

The primary goals of the school breakfast program are to reduce food-insecurity among low-income students and to decrease the growing habit of breakfast skipping. Consumption of school breakfast has been associated with improved health and academic performance. The purpose of this review was to investigate these alleged beneficial outcomes and to evaluate the program’s success in promoting accessibility and participation for all students. Results showed that children who ate a school breakfast were more likely to have a healthier BMI and a broader daily nutrient intake. Participation also helped students achieve higher math and reading grades. Their teachers reported improvements …

Pillow Talk, Winston J. Craig

Lake Union Herald

No abstract provided.