Digital Commons Network^™

Regulation Of Obesity And Metabolic Complications By Gamma And Delta Tocotrienols, Lu Zhao, Xiefan Fang, Maurice R. Marshall, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Tocotrienols (T3s) are a subclass of unsaturated vitamin E that have been extensively studied for their anti-proliferative, anti-oxidative and anti-inflammatory properties in numerous cancer studies. Recently, T3s have received increasing attention due to their previously unrecognized property to attenuate obesity and its associated metabolic complications. In this review, we comprehensively evaluated the recent published scientific literature about the influence of T3s on obesity, with a particular emphasis on the signaling pathways involved. T3s have been demonstrated in animal models or human subjects to reduce fat mass, body weight, plasma concentrations of free fatty acid, triglycerides and cholesterol, as well as …

Successfully Changing The Landscape Of Information Distribution: Extension Food Website Reaches People Locally And Globally, Alice Henneman, Lisa Franzen-Castle, Kayla Colgrove, Vishal Singh

Department of Nutrition and Health Sciences: Faculty Publications

The goal of the Food website was to develop Internet-based content that was relevant and reached the general public and multiplier groups, such as educators, health professionals, and media outlets. The purpose of this paper was to examine whether a multi-modal approach to information delivery through increases in and changes to content, electronic mailing list creation, and social media posting impacted user access, traffic channels, and referrals from 2010 to 2014. When comparing 2010-2011 versus 2013-2014, there was a 150% increase in total pageviews, 197% increase in unique pageviews, and a 39% increase in average time spent on a page. …

Public Health Leaders' Perceptions Of And Attitudes Concerning Eating Disorders, Karin L. Lightfoot

Walden Dissertations and Doctoral Studies

Eating disorders are associated with high mortality rates. Most eating disorder prevention research is conducted within the fields of psychology and psychiatry, not in public health. This gap in public health research can lead to insufficient attention to the root causes of eating disorders and minimal upstream prevention efforts. The purpose of this phenomenological study was to identify public health leaders' perceptions of and attitudes concerning eating disorders as a public health issue. Objectification theory was used to describe how societal expectations have created an environment in which people's self-worth is based on their outward physical appearance. Ecological theory was …

Food Labeling And Consumer Associations With Health, Safety, And Environment, Joanna K. Sax, Neal Doran

Faculty Scholarship

The food supply is complicated and consumers are increasingly calling for labeling on food to be more informative. In particular, consumers are asking for the labeling of genetically modified organisms (GMO) food based on health, safety and environmental concerns. At issue is whether the labels that are sought would accurately provide the information desired. The present study examined consumer (n = 181) perceptions of health, safety and the environment for foods labeled organic, natural, fat free or low fat, GMO, or non-GMO. Findings indicated that respondents consistently believed that foods labeled GMO are less healthy, safe and environmentally-friendly compared to …

Effect Of Maternal Diet On Select Fecal Bacteria In Mares And Their Foals, Morgan Brewer Pyles

Theses and Dissertations--Animal and Food Sciences

The process of microbial colonization in the gastrointestinal tract of foals and the factors influencing this process are not well understood. The objectives were to determine the effect of starch source in pelleted concentrates in the maternal diet on select fecal bacterial groups in mares and their foals and to evaluate changes in these bacterial groups over time. Thoroughbred foals (n=19) were from dams fed one of two concentrates: an oat-based (OB) or corn and wheat middling-based (CWB) pelleted concentrate. Fecal samples were collected from mares at 324 d of gestation, pre-foaling, 1 d, 14 d, and 28 d after …

The Influence Of Time On Food Intake Patterns: Age, Period, Cohort Differences, Karina L. Christopher

Theses and Dissertations--Gerontology

The impact of diet and exercise on overall health and chronic disease risk has been well examined. Multiple studies show that Americans eat more now than they did fifty years ago. What isn’t known is how much of an impact time has on food intake patterns of individuals in terms of different age groups, historic periods of structural influences, and birth cohorts.

In order to identify the impact of time on food intake this study examined time from multiple perspectives. The first aim of this study was to determine food intake patterns among age groups across five time periods using …

A Qualitative Analysis Of Barriers To And Facilitators Of Successful Weight Loss, Alyson Drooger

Electronic Theses and Dissertations

Background: Along with the United States obesity epidemic comes extensive weight loss attempts. One way people are attempting to lose weight is through meal replacement programs. Much work has been done to study strategies of structured weight loss programs and examine their success. Limited work has been done to study the specific barriers and facilitators of the real life participants who join weight loss programs. The purpose of this study is to identify, through qualitative research methods, the barriers to and facilitators of weight loss while participating in a meal replacement program.

Methods: Twenty-nine members of a meal replacement program …

Icook 4-H: Report Of Accelerometer Derived Physical Activity In 9-10 Year Old Children From Baseline, Post, And Follow-Up, Chase Merfeld

Electronic Theses and Dissertations

To examine the relationship between baseline, post, and follow-up accelerometer derived physical activity (PA) in 9-10 year old children participating in iCook 4-H, a 16-week, 5- state, randomized control family centered childhood obesity prevention program. This family focus intervention was designed to promote PA through lifestyle modifications. Between group differences in minutes-per-day and intensity of PA were determined on accelerometer compliant participants. All subjects wore an accelerometer (Actigraph GT3X+) for 7 days at baseline, post, and follow-up intervention assessment. Mean daily minutes of accelerometer derived sedentary time (ST) and PA including light (LPA), moderate (MPA), vigorous (VPA) and moderate-to-vigorous (MVPA) …

Influencers And Barriers To Consumption Of Healthful Diets In Rural Youth In Context Of The Bioecological Model, Megan Bren

Electronic Theses and Dissertations

The purpose of this study is to determine influencers and barriers to healthful dietary intake in rural youth in context of the bioecological model. Four focus groups as part of Ignite, a tri-state, five-year, community based partipatory research (CBPR) intervention were conducted with 6th to 8th grade adolescents from an economically disadvantaged community of rural South Dakota. Results were categorized into the context of the bioecological model. Within the model, the process, person, context and time (PPCT) design with the three types of personal characteristics were used to describe the framework in which the systems are embedded. Focus group content …

Contents, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 17 2016, Several Authors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Bumpers College Students In Action, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Genotoxic Effects Of Magnesium Deficiency In The Cardiovascular System And Their Relationships To Cardiovascular Diseases And Atherogenesis, Burton M. Altura, Nilank C. Shah, Gatha J. Shah, Bella T. Altura

The School of Health Sciences Publications and Research

The authors present evidence for a novel, new hypothesis whereby magnesium deficiency (MgD) acts as a genotoxic agent which probably causes numerous, hertofore, unrecognized consequences, even over a short-term, on the physiological, molecular and biochemical machinery of cardiovascular tissues and cells. The end result of these genotoxic effects of MgD probably plays important roles in the etiology and generation of diverse cardiovascular diseases, atherosclerosis, inflammation, and strokes via alterations in the epigenome of cardiovascular tissues and cells. The importance of adequate water-borne and dietary levels of Mg is emphasized.

The Expression Of Platelet-Activating Factor Is Induced By Low Extracellular Mg2+ In Aortic, Cerebral And Neonatal Coronary Vascular Smooth Muscle; Cross Talk With Ceramide Production, Nf–Kb And Proto-Oncogenes: Possible Links To Atherogenesis And Sudden Cardiac Death In Children And Infants, And Aging: Hypothesis, Review And Viewpoint, Burton M. Altura, Wenyan Li, Aimin Zhang, Tao Zheng, Nilank C. Shah, Gatha J. Shah, Bella T. Altura

The School of Health Sciences Publications and Research

An attempt is made, herein, to reconcile, and integrate, various phenomena associated with magnesium deficiency (MgD) in cardiovascular health, disease, and aging as well as reasons for the high incidence of sudden cardiac death in infants and young adults. With new experiments, we demonstrate, for the first time, that very low concentrations of platelet-activating factor (PAF), when added to primary cultured cerebral, neonatal coronary, and aortic vascular smooth muscle (VSM) cells (from three different mammals) promote rapid rises in free intracellular Ca2+ ions and a significant, concomitant reduction in free intracellular Mg2+ ions; these actions of PAF being curtailed with …

Potential Roles Of Magnesium Deficiency In Inflammation And Atherogenesis: Importance And Cross-Talk Of Platelet-Activating Factor And Ceramide, Burton M. Altura, Asefa Gebrewold, Nilank C. Shah, Gatha J. Shah, Bella T. Altura

The School of Health Sciences Publications and Research

Epidemiologic studies in North America and Europe have shown that people consuming Western-type diets are low in magnesium (Mg) content (i.e., < 30 - 65% of the RDA for Mg); most such diets in the USA show that 60 - 80% of Americans are consuming only 185 - 235 mg/day of Mg. Low Mg content in areas of soft-water, and Mg-poor soil, is associated with high incidences of ischemic heart disease (IHD), coronary artery disease, hypertension, and sudden cardiac death (SCD). It is clear that the leading underlying cause of death worldwide is atherosclerosis. Importantly, both animal and human studies have shown an inverse relationship between dietary intake of Mg and atherosclerosis. The myocardial level of Mg has consistently been observed to be lower in subjects dying from IHD and SCD in soft-water areas than those in hard-water areas. Over the past 20 years, our laboratories, using several types of primary cultured vascular smooth muscle (VSM) cells, and myocardial cells, demonstrated that declining levels of extracellular Mg ([Mg2+]0) activated several enzymatic pathways to produce increases in cellular sphingolipids, particularly ceramides which are known to exert numerous types of cardiovascular manifestations including inflammatory effects; the latter play important roles in atherogenesis and cardiovascular diseases. Approximately 20 years ago, we reported that low [Mg2+]0 caused formation of platelet-activating factor (PAF) as well as other types of PAF-like molecules and suggested that these molecules might be causative agents in low Mg2+- induced IHD and SCD. Herein, we review results and data from our labs which strongly support roles for ceramides, PAF and PAF-like lipids in low [Mg2+]0-induced IHD and SCD.

Successful Weight Management: Barriers And Facilitators To Maintaining Weight After Weight Loss Via A Meal Replacement Program, Hope D. Kleine

Electronic Theses and Dissertations

Purpose: Meal replacement programs (MRPs) facilitate weight loss. Unfortunately, a large percentage of individuals that lose weight through MRP are not successful at maintaining their weight. Weight regain one year following weight loss via meal replacements has been as high as 40-50%, demonstrating a critical need to improve weight maintenance in MRP participants. Therefore, the purpose of this study is to identify barriers and facilitators of weight maintenance after reaching a goal weight in MRP participants.

Methods: Seven focus groups of ≤8 clients were conducted to discuss barriers and facilitators of weight maintenance prior to reaching a point of …

The Healthfulness Of Entrées And Students’ Purchases In The Campus Dining Environment, Krista Leischner

Electronic Theses and Dissertations

The purpose of this study is to determine the availability of “more” versus “less healthful” entrée items in the campus dining environment and also to determine if students’ purchases are reflective of what is offered.
Entrée items were categorized as either “more” or “less healthful” according to the American Heart Association guidelines. Students’ entrée purchases from the 2014- 2015 school year were analyzed at a Midwestern university. The relationship between students’ demographics and food purchases was also analyzed in this observational study. Significant differences between more healthful and less healthful purchased and available items were determined using a Chi-square test. …

Differences In Running Mechanics Between Overweight/Obese And Healthy Weight Children, Kristen Roles

Electronic Theses and Dissertations

Background/Purpose: Physical activity is commonly prescribed to reduce childhood obesity. However, due to differences in mechanics during low-impact activities, such as walking, obese children may be more prone to negative physical complications during high-impact activities, such as running. Therefore, this study analyzed the mechanical differences in running mechanics between healthy weight (HW) and overweight/obese (OV/OB) children. We hypothesized that when compared to HW children, OV/OB children would display higher vertical loading, greater joint moments and greater joint angular impulses during running. We also expect decreased sagittal plane range of motion and increased frontal plane range of motion of the hip, …

Icook 4-H: 0 To 24-Month Accelerometer-Derived Physical Activity And Sedentary Time In Youth, Emily Hofer

Electronic Theses and Dissertations

To assess accelerometer-derived physical activity and sedentary time from 0 to 24- months in youth in the iCook 4-H program. The iCook 4-H Program was a 5-state, randomized, control-treatment, family-based childhood obesity prevention intervention promoting cooking, eating and playing together. Youth, 9-10 years old, and their main adult meal preparer, participated in the 12-week program followed by monthly newsletters and bi-yearly booster sessions until 24-months. Physical activity and sedentary time were determined for youth who wore an Actigraph GT3X+ accelerometer for 7 days at 0, 4, 12, and 24-months and met defined accelerometer compliance standards. Mean daily minutes of sedentary …

Relationships Between Behavioral Measures And Productivity In Finishing Beef Cattle, Jasmyn Mimiko

Theses and Dissertations--Animal and Food Sciences

The relationship between measures of temperament, growth performance, and social hierarchy in finishing beef cattle were explored in two experiments. In experiment 1, high OCS (objective chute score) steers had periods of significantly higher ADG (P < 0.01), but OCS had no relationship with dominance ranking (P > 0.47). Conversely, slow exit velocity (EV) correlated with higher ranking (P ≤ 0.06), but EV had no relationship with performance (P > 0.37) in a competitive environment. Rank showed no relationship with performance (P > .58). In experiment 2, steers with fast EV had periods of decreased growth (P ≤ .06), intake (P ≤ .06), and gain:feed (G:F; P = 0.02). There were no interactions between …

Postprandial Paraoxonase 1 Activity Following Consumption Of Recommended Amounts Of Mixed Meals In Healthy Males, Noriko Kameyama, Chizuko Maruyama, Kazuhiko Kotani, Russell Caccavello, Alejandro Gugliucci, Sadako Matsui, Taro Maruyama

Faculty Publications & Research of the TUC College of Osteopathic Medicine

Aim: Postprandial lipid level increases induce oxidative stress, which is involved in atherogenesis. The antioxidant properties of paraoxonase 1 (PON1) have attracted attention. However, changes in postprandial PON1 levels differ across prior studies, and changes in PON1 lactonase activity, potentially relevant to PON1 physiology, after the consumption of ordinary meals are unknown. Herein we evaluated postprandial serum lipid levels and PON1 changes following mixed-meal consumption of the amounts recommended for ordinary meals.
Methods: Nine healthy male volunteers consumed three different meals in a randomized cross-over design. The test meals were as follows: S, white rice; SMF, S with …

A Study Of The Effectiveness Of Front-Of-Package Nutrition Labels In The Us, Emily Lauren Irvin

Electronic Theses and Dissertations

American weight trends have steadily increased over the past years. In efforts to better inform consumers of their food consumption, increasingly front-of-package (fop) food labels are displayed on packaged food items. Fop nutrition labels have become more prevalent in the US to help consumers identify healthier options at the point-of-purchase. This study aimed to evaluate the effectiveness of two current fop labels, the facts up front and the facts up front extended labels. In addition, a generic binary label was created to represent a non-brand associated symbol, which does not currently exist in the US. Participants were randomized to one …

Predisposing Risk Factors Associated With Stress Fracture Development In Division I Cross Country Runners, Kaci Griffin

Electronic Theses and Dissertations

The purpose of this study was to explore potential factors that could be associated with increased stress fracture development in division one collegiate cross country runners. Participants for this study consisted of 42 collegiate cross country runners at the University of Mississippi. A nutritional assessment consisting of a 3-day food record and measurements of whole body, lumbar spine and hip bone mineral densities using a Dual-Energy X-ray Absorptiometry (DXA) was conducted on each athlete. Each athlete was also asked to answer a demographic questionnaire with questions regarding ethnicity, hometown, smoking status, vitamin/mineral intake, previous stress fracture history, birth control usage …

Female Natural Bodybuilding Competition Preparation: A 6-Week Case Study, Samantha G. Gwazdauskas

College of Graduate Studies: Theses & Dissertations

Bodybuilding is unlike any other sport. Competitors are judged on appearance rather than performance, where muscle size and definition are keys to achieving success. This case study tracked four, drug-free, female bodybuilders for 6-weeks leading up to their competitions. The purpose of this project was to examine the physiological and psychological experiences of female bodybuilders as they prepare for competition. Each competitor reported for testing at three occasions to evaluate cardiovascular measures, body composition, resting metabolic rate, performance measures of strength, power, muscular endurance, and maximal oxygen consumption, mood state, social physique anxiety, and overall experience. Each subject in this …

Histological Evidence Of The Effect Of Oil Palm Phenolics In Atherogenic Diet Induced Rat Model Of Alzheimer’S Disease, Kenechukwu Monplaisir Monplaisir

Wayne State University Theses

BACKGROUND: Alzheimer’s disease (AD) is a neurodegenerative disease with the clinical presentation of memory loss and cognitive impairment. Alzheimer's disease pathology is the accumulation of beta amyloid plaques and neurofibrillary tangles.

METHOD: In this study atherogenic diet was used to induce AD in aged Brown Norway rats. The rats were assigned to the following four groups fed isocaloric diets; control group (C ),high cholesterol diet (H), high cholesterol + oil palm phenolics group (HP), high cholesterol + curcumin group (HC). The impact of oil palm phenolics (OPP) on neuronal health and its effect on amyloid deposition was evaluated using histology …

Relationships Of Dietary Protein And Phosphorus With Protein Energy Wasting In Hemodialysis Patients, Dina Angela Tallman

Wayne State University Theses

Both higher dietary phosphorus intake and a greater dietary phosphorus to protein ratio are associated with increased death risk in hemodialysis (HD) patients even after adjustments for serum phosphorus, type of phosphate binder used, and dietary protein, energy, and potassium intake. Furthermore, dietary phosphorus restriction to control serum phosphorus is often associated with a reduction in protein intake, which is associated with muscle wasting and poor survival. One highly prevalent complication of end stage renal disease is protein energy wasting (PEW), a state of decreased body protein and fat mass, which is strongly associated with increased morbidity and mortality in …

Success Stories And Emerging Themes In Conservation Physiology, Christine L. Madliger, Steven J. Cooke, Erica J. Crespi, Jennifer L. Funk, Kevin R. Hultine, Kathleen E. Hunt, Jason R. Rohr, Brent J. Sinclair, Cory D. Suski, Craig K. R. Willis, Oliver P. Love

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The potential benefits of physiology for conservation are well established and include greater specificity of management techniques, determination of cause–effect relationships, increased sensitivity of health and disturbance monitoring and greater capacity for predicting future change. While descriptions of the specific avenues in which conservation and physiology can be integrated are readily available and important to the continuing expansion of the discipline of ‘conservation physiology’, to date there has been no assessment of how the field has specifically contributed to conservation success. However, the goal of conservation physiology is to foster conservation solutions and it is therefore important to assess whether …

Implementing Pasteurized Donor Human Milk Programs In Level One And Two Nurseries: Policies, Barriers, And Successes, Rebecca Phipps Smeltzer

Honors Theses and Capstones

Pasteurized donor human milk (PDHM) as feeding supplementation has been shown to prevent and lower rates of gastrointestinal infection and increase exclusive human milk consumption (EHM) in critically-ill, low birthweight and premature infants. Policies/ procedures for the use of PDHM in “well” newborns and low birth weight newborns with non-life-threatening illness, level I and II nurseries, respectively, have not been established. The objective of this research is to gather and summarize policies/procedures and experiences from four hospitals in the northeast US that use PDHM in level I/II nurseries. Data was collected from interviews with hospital administrators and each hospital’s PDHM …

A Dietary Approach To Cardiovascular Disease And Cancer: Does A Plant Based Diet Help Prevent And Reverse Cardiovascular Disease And Cancer?, Chana Wircberg

The Science Journal of the Lander College of Arts and Sciences

Modern Western societies seem to suffer from a veritable epidemic of serious diseases, two of the most serious of which are cardiovascular disease and cancer. In contrast, hunter and gatherer groups have a very low incidence of such diseases. Despite the diversity of hunter and gather diets, they all share the same characteristic: the absence of a Western diet. This suggests that there is something uniquely inflammatory about a Western diet, which is high in both fats and carbohydrates. Departures from a Western diet appear to result in better health. Experimental studies have shown that heart disease can be reversed …

Letter From The Dean, Lona Robertson

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.