Digital Commons Network^™

Teen Obesity: Tips To Take Control Of Your Diet And Make A Difference Every Day, Zachary York

All Student-Created Educational Resources

This handout provides an overview of obesity and includes tips designed to motivate and assist teenagers toward making healthy choices to support overall health and well-being. Topics range from identifying nutritious foods, knowing when to eat, how to become more physically active, and having fun with food. The goal of the handout is to provide accessible and easy to understand information to empower overweight adolescents to make important connections eating well, exercising, and how they look and feel on a day-to-day basis.

Choline: Exploring The Growing Science On Its Benefits For Moms And Babies, Hunter W. Korsmo, Xinyin Jiang, Marie A. Caudill

Publications and Research

The importance of ensuring adequate choline intakes during pregnancy is increasingly recognized. Choline is critical for a number of physiological processes during the prenatal period with roles in membrane biosynthesis and tissue expansion, neurotransmission and brain development, and methyl group donation and gene expression. Studies in animals and humans have shown that supplementing the maternal diet with additional choline improves several pregnancy outcomes and protects against certain neural and metabolic insults. Most pregnant women in the U.S. are not achieving choline intake recommendations of 450 mg/day and would likely benefit from boosting their choline intakes through dietary and/or supplemental approaches.

Decomposing Trends In Child Obesity, Ashley Wendell Kranjac, Robert L. Wagmiller

Sociology Faculty Articles and Research

We unravel the absolute level and relative prominence of two demographic processes that are relevant for childhood obesity, and that will ultimately determine the long-term course and pace of change in child obesity rates. We leverage data from the National Health and Nutrition Examination Survey to decompose change in child obesity from 1971 to 2012. We partition change into that attributable to (1) healthier, more nutritionally and economically advantaged cohorts in the population being replaced by cohorts of children who are less advantaged (between-cohort change), and (2) the health habits, nutrition, and social and economic circumstances of all cohorts of …

Effects Of Multivitamin-Mineral Supplementation On Mental Health Among Young Adults, Ya-Hsuan Chang

Graduate Theses and Dissertations

The percentage of young adults who had mental illnesses has increased from 2008 to 2015. However, few existing studies investigating the potential benefits of multivitamin-mineral (MVM) supplementation on mental health focused on young adults (18-24 years of age), whose eating behaviors are often unhealthy. The purpose of this study was to examine the effects of a MVM supplement on mental health in young adults. One hundred and thirty-three college students (Mage=20.59, SD=1.77; 80.15% female) participated in this randomized, double-blind, placebo-controlled trial. Participants consumed either a MVM supplement or a placebo for 30 days. The supplement contained B Vitamins, Vitamin C, …

Incorporating Technology Into The Icook 4-H Program, A Cooking Intervention For Adults And Children: Randomized Controlled Trial, Sarah Colby, Lauren Moret, Melissa D. Olfert, Kendra Kattelmann, Lisa Franzen-Castle, Kristin Riggsbee, Magen Payne, Ainsley Ellington, Cary Springer, Chelsea Allison, Sanearlda Wiggens, Rochelle Butler, Douglas Mathews, Adrienne A. White

Health and Nutritional Sciences Faculty Publications

Background: Families who cook, eat, and play together have been found to have more positive health outcomes. Interventions are needed that effectively increase these health-related behaviors. Technology is often incorporated in health-related interventions but is not always independently assessed.
Objective: The objective of this study was to describe challenges and facilitators to incorporating technology into the iCook 4-H intervention program.
Methods: Dyads (n=228) composed of children (mean 9.4, SD 0.7 years old) and an adult primary meal preparer (mean 39.0, SD 8 years) were randomly assigned to a control (n=77) or treatment group (n=151). All treatment group dyads participated in …

Oxygenation And Activation Of The Vastus Lateralis During Dynamic Constant External Resistance Leg Extension Muscle Actions In Older Women With And Without Sarcopenia, Brianna D. Mckay

College of Education and Human Sciences: Dissertations, Theses, and Student Research

The purpose of the present study was to compare muscle strength, size, activation, and oxygenation between older women with and without sarcopenia during dynamic fatiguing leg extension bouts with high (5-repetition maximum[5-RM]) and low (30% of estimated 1-RM[30%1-RM]) loads. Eleven women (n = 6 non-sarcopenic [mean ± SE; age = 75.8 ± 2.6y] and n = 5 sarcopenic [age = 74.5 ± 3.1y]) were screened for eligibility and sarcopenic status. Descriptive assessments including demographics (age, height, and weight), body composition by dual-energy x-ray absorptiometry (fat mass[FM], fat-free mass[FFM] and percent body fat[BF%]), muscle size by ultrasonography (leg extensor muscle cross-sectional …

3-Hydroxy Fatty Acids Induce Retinal Pigment Epithelial Cell Lipoapoptosis, Mona Hadidi

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Mitochondrial fatty acid oxidation (FAO) plays an important role in maintaining metabolic homeostasis, especially during catabolic stress. Genetic mutation in gene that encodes for mitochondrial FAO enzymes could result in metabolic stress especially during fasting or hypoglycemic condition. Mutation in the active site residue (1528G>C) of long chain 3-hydroxy acyl CoA dehydrogenase (LCHAD) results in the loss of LCHAD enzyme activity. Children’s with LCHAD mutation were known to accumulate 3-hydroxy fatty acids such as 3-hydroxy palmitic acid and 3-hydroxy myristic acids, long chain free fatty acids, acyl carnitine and 3-hydroxy dicarboxylic acid due to their defective enzyme activity. These …

Inhibitory Effects Of Shiitake-Derived Exosome-Like Nanoparticles On Nlrp3 Inflammasome Activation, Yizhu Lu

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

The NLRP3 inflammasome is a critical mediator of inflammation and consists of the sensor NOD-like receptor family, pyrin domain containing 3 (NLRP3), the adaptor apoptotic speck protein containing a caspase recruitment domain (ASC), and the effector caspase-1. Dysregulated or excessive activation of the NLRP3 inflammasome contributes to pathogenesis of diverse inflammatory diseases such as Type 2 diabetes and atherosclerosis. Therefore, the NLRP3 inflammasome is a promising therapeutic target for treating these diseases. Extracellular vesicles (EVs) are membrane-enclosed tiny particles released by almost any type of cells and they are involved in the intercellular communication by transferring their cargos including RNAs, …

Transport And Distribution Of Bovine Milk Exosomes And Mir-34a Cargo In Murine Cerebral Cortex Endothelial Bend.3 Cells And Bv2 Microglia, Pearl Ebea

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

The blood-brain barrier (BBB) poses an obstacle in the delivery of drugs to the brain. Bovine milk exosomes (BME) are explored for delivering antisense oligonucleotides to tumors, because BME are bioavailable and protect RNA cargos against degradation in the gastrointestinal tract. This study had the following objectives: 1) assess the transport kinetics of BME and their RNA cargos and secretion of RNA across the apical membrane in murine cerebral cortex endothelial bEnd.3 cells and 2) determine whether murine brain BV2 microglia have the potential to accumulate and, therefore, eliminate BME that crossed the BBB. The uptake of BME labeled with …

The Effects Of Branched Chained Amino Acid Supplementation On Acute Markers Of Fatigue And Performance, Joseph Walters

Electronic Theses and Dissertations

The purposes of this dissertation were to investigate the acute effects of branched-chain amino acids on psychological, physiological, and subsequent performance changes following high volume resistance training. The rationale for this study design was based on abrupt or contiguous training/ competitions that specific athletes encounter in a competitive season. This study design also sought to fill some gaps in the scientific literature concerning the efficacy of BCAAs for subjective fatigue in a resistance training paradigm. To address the purposes of this dissertation, a one-week study was conducted on resistance trained males, in which half of the subjects were randomly selected …

Leaf Fiber Strength And Fruit Nutrient Content Of Yucca Species Native To The Navajo Nation, Anna Therese Bartlett

Theses and Dissertations

The strength of leaf fibers and the nutritional value of the edible fruit of several yucca species native to the U.S. southwest were studied to aid in the determination of species best suited for commercial cultivation by the Navajo Nation. The leaves were softened in an autoclave to facilitate the removal of the leaf matrix, conditioned in environmentally controlled chambers, and the fibers were broken using a texture analyzer. The fibers were frozen and cross sectioned and photographed to determine cross sectional area. Official methods were used to determine the nutritional content of the fruit. The mean tensile strength of …

Influences Of Autism Spectrum Disorder On Sensory And Emotional Responses To Smell And Taste Cues, Asmita Singh

Graduate Theses and Dissertations

Autism spectrum disorder (ASD) is a developmental disability that causes social, communication, behavioral and sensory challenges. The prevalence has been on a rise, with the latest reports stating 1 in 59 children is diagnosed with ASD. These challenges play a significant role in feeding behavior, leading to reduced nutrition among individuals. Much research in this field has been attributed to children, however, this study was focused on the adult population, in an attempt to improve their quality of life. Building on previous findings and knowledge gaps, the objectives of this thesis were two-fold: To better understand the sensory experiences of …

Prediction And Evaluation Of Breast Myopathy, Barbara De Almeida Mallmann

Graduate Theses and Dissertations

Broiler breast myopathies, including woody breast, white striping, and spaghetti breast, negatively impact the industry. Therefore, evaluation, prediction, and frequency of these muscle abnormalities on modern birds are important for decision making. Modern broilers are not highly active and often sit with the breast of the bird resting on the floor. Therefore, the first experiment was to promote bird movement and explore the impact on the breast myopathies. The movement was stimulated by human interaction (walking through pen) and higher light intensity so that birds walked around the pen more often throughout the day. The control group had normal low …

Retrospective Evaluation Of A Dietitian-Led Corporate Wellness Program, Catherine Johnston

Graduate Theses

BACKGROUND: Despite national health and wellness standards, many adults are not compliant with a healthy lifestyle, especially in the southeastern region of the United States. Effective corporate wellness programs are a mutually beneficial method of promoting health among this population. OBJECTIVE: The aim of this study was to evaluate effectiveness of a Registered Dietitian (RD) developed 12-week corporate wellness program for improved health parameters, nutrition knowledge scores and comparable retention rates.

Diets And Irritable Bowel Syndrome, Zahra Darabi, Amin Mokari-Yamchi, Masoomeh Hajizadehoghaz, Arezoo Rezazadeh

Department of Nutrition and Health Sciences: Faculty Publications

Introduction: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, which is characterized by the presence of abdominal pain or discomfort associated with altered bowel habits. This systematic review aimed to assess the nutritional factors (dietary patterns and food groups) associated with IBS.

Methods: Articles were collected via searching in databases such as Medline, EMBASE, CINAHL, ProQuest, PubMed, Scopus, ScienceDirect, and Google Scholar using relevant keywords and phrases, including irritable bowel syndrome, pattern, intake, behavior, habit, meal, nutrition, food, lifestyle, and prevalence. The articles were confined to the original human studies that were published in English since 2010. …

Inter- And Intra-Individual Differences In Emg And Mmg During Maximal, Bilateral, Dynamic Leg Extensions, John Paul V. Anders, Cory M. Smith, Joshua L. Keller, Ethan C. Hill, Terry J. Housh, Richard Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

The purpose of this study was to compare the composite, inter-individual, and intra-individual differences in the patterns of responses for electromyographic (EMG) and mechanomyographic (MMG) amplitude (AMP) and mean power frequency (MPF) during fatiguing, maximal, bilateral, and isokinetic leg extension muscle actions. Thirteen recreationally active men (age = 21.7 2.6 years; body mass = 79.8 11.5 kg; height = 174.2 12.7 cm) performed maximal, bilateral leg extensions at 1801 until the torque values dropped to 50% of peak torque for two consecutive repetitions. The EMG and MMG signals from the vastus lateralis (VL) muscles of both limbs were recorded. Four …

Prioritization Of Variants For Investigation Of Genotype-Directed Nutrition In Human Superpopulations, Pascal D. Nilsson, Jacklyn M. Newsome, Henry M. Santos, Martin R. Schiller

Life Sciences Faculty Research

Dietary guidelines recommended by key health agencies are generally designed for a global population. However, ethnicity affects human disease and environment-gene interactions, including nutrient intake. Historically, isolated human populations with different genetic backgrounds have adapted to distinct environments with varying food sources. Ethnicity is relevant to the interaction of food intake with genes and disease susceptibility; yet major health agencies generally do not recommend food and nutrients codified by population genotypes and their frequencies. In this paper, we have consolidated published nutrigenetic variants and examine their frequencies in human superpopulations to prioritize these variants for future investigation of population-specific genotype-directed …

Gut Microbiome: Profound Implications For Diet And Disease, Ronald D. Hills Jr., Benjamin A. Pontefract, Hillary R. Mishcon, Cody A. Black, Steven C. Sutton, Cory R. Theberge

Pharmaceutical Sciences Faculty Publications

The gut microbiome plays an important role in human health and influences the development of chronic diseases ranging from metabolic disease to gastrointestinal disorders and colorectal cancer. Of increasing prevalence in Western societies, these conditions carry a high burden of care. Dietary patterns and environmental factors have a profound effect on shaping gut microbiota in real time. Diverse populations of intestinal bacteria mediate their beneficial effects through the fermentation of dietary fiber to produce short-chain fatty acids, endogenous signals with important roles in lipid homeostasis and reducing inflammation. Recent progress shows that an individual’s starting microbial profile is a key …

Cooking And Meal Planning As Predictors Of Fruit And Vegetable Intake And Bmi In First-Year College Students, Andrea J. Hanson, Kendra Kattelmann, Lacey A. Mccormack, Wenjun Zhou, Onikia N. Brown, Tanya M. Horacek, Karla P. Shelnutt, Tandalayo Kidd, Audrey Opoku-Acheampong, Lisa Franzen-Castle, Melissa D. Olfert, Sarah E. Colby

Department of Nutrition and Health Sciences: Faculty Publications

The objective was to determine if cooking skills and meal planning behaviors are associated with greater fruit and vegetable intake and lower body mass index (BMI) in first-year college students who are at risk for excessive weight gain. A cross-sectional analysis was conducted using baseline data from a multi-state research project aimed at preventing weight gain in first-year college students. Cooking type, frequency and confidence, self-instruction for healthful mealtime behavior intention, self-regulation of healthful mealtime behavior, and cup equivalents of fruits and vegetables (FV) were measured using validated surveys. BMI was calculated from measured height and weight. First-year students (n …

Pregnant Women In Four Low-Middle Income Countries Have A High Prevalence Of Inadequate Dietary Intakes That Are Improved By Dietary Diversity, Rebecca L. Lander, K Michael Hambidge, Jamie E. Westcott, Gabriela Tejeda, Tshilenge S. Diba, Shivanand C. Mastiholi, Umber S. Khan, Ana Garcés, Sumera Aziz Ali, Sarah Saleem, On Behalf Of The Women First Preconception Nutrition Trial Group

Community Health Sciences

Background: Up-to-date dietary data are required to understand the diverse nutritional challenges of pregnant women living in low-middle income countries (LMIC). To that end, dietary data were collected from 1st trimester pregnant women in rural areas of Guatemala, India, Pakistan, and Democratic Republic of the Congo (DRC) participating in a maternal lipid-based nutrient supplement (LNS) Randomized Controlled Trial to examine dietary diversity (DD), usual group energy and nutrient intakes, and prevalence of inadequate dietary intakes.
Methods: Two 24-h dietary recalls were conducted in ~240 pregnant women/site (total n = 966) prior to 12-week gestation. Adequate DD was assessed, i.e., ≥5 …

The Impact Of Framing On Acceptance Of Cultured Meat, Christopher Bryant, Courtney Dillard

University Studies Faculty Publications and Presentations

Cultured meat can be produced from growing animal cells in-vitro rather than as part of a living animal. This technology has the potential to address several of the major ethical, environmental, and public health concerns associated with conventional meat production. However, research has highlighted some consumer uncertainty regarding the concept. Although several studies have examined the media coverage of this new food technology, research linking different frames to differences in consumer attitudes is lacking. In an experimental study, we expose U.S. adults (n = 480) to one of three different frames on cultured meat: “societal benefits,” “high tech,” and “same …

Photo Elicitation Study 2018-2019, Lisa Armstrong, Kaela Edwards, Violetta Feshchenko, Kimberly Kullmann, Alexandre Martinez, Rebecca Mercier, Nicole Murray, Pamela Myers, Priyanka Prasad, Victoria Ramos, Nicholas Salter, Madalene Zale, Amy Henderson Riley, Drph, Rosemary Frasso, Phd, Adrea Cope, Nataki Duncan, Rachel Ewalt, Catherine Freeland, Nichole Holmes, Laura Slifer, April Smith, Sabina Spigner, Simal Thind, Eliza Whiteman Kinsey, Phd

JCPH at APHA 2019

Photographer and researcher John Collier first named photo elicitation in a paper published in 1957. Photo elicitation involves a qualitative interview stimulated and guided by participant photographs. This method can help break down barriers between researchers and participants and can promote rich and collaborative discussions (Harper, 1994).

Student Perspectives on Work-Life Balance: A Photo Elicitation Study

Each student in Qualitative Research Methods (PBH 512, Summer 2018) recruited a study participant (n=12) from across the colleges of Thomas Jefferson University. Students trained participants in the appropriate and ethical use of this method. Study participants were asked to define and explore the …

Cooking And Meal Planning As Predictors Of Fruit And Vegetable Intake And Bmi In First-Year College Students, Andrea Hanson, Kendra K. Kattelmann, Lacey A. Mccormack, Wenjun Zhou, Onika N. Brown, Tanya M. Horacek, Karla P. Shelnutt, Tandalayo Kidd, Audrey Opoku-Acheampong, Lisa Franzen-Castle, Melissa D. Olfert, Sarah E. Colby

Health and Nutritional Sciences Faculty Publications

The objective was to determine if cooking skills and meal planning behaviors are associated with greater fruit and vegetable intake and lower body mass index (BMI) in first-year college students who are at risk for excessive weight gain. A cross-sectional analysis was conducted using baseline data from a multi-state research project aimed at preventing weight gain in first-year college students. Cooking type, frequency and confidence, self-instruction for healthful mealtime behavior intention, self-regulation of healthful mealtime behavior, and cup equivalents of fruits and vegetables (FV) were measured using validated surveys. BMI was calculated from measured height and weight. First-year students (n …

Food And Culture Fact Sheet Vietnam, Une Applied Nutrition Program

All Student-Created Educational Resources

This handout describes Vietnamese cultures and traditional diet. Vietnamese dishes are often built around rice, broth, and layers of flavor. The Vietnamese people have several nutritional and health beliefs stemming from Chinese traditional medicine. Vietnam has one of the most famous market and street food culture of the world.

Development, Validation, And Testing Of The Eating And Food Literacy Behaviors Questionnaire With Young Adult University Students, Kwadernica Rhea

LSU Doctoral Dissertations

The Eating and Food Literacy Behaviors Questionnaire (EFLBQ) was developed, and its validity, reliability, and ability to measure construct changes was established. Items related to the originally proposed domains of food literacy were included in the initial questionnaire, however five, new components were discovered. The second version of the EFLBQ was tested with 257 young adult university students using exploratory factor analysis, and a five-factor model (R²=57.4%) was returned. Cronbach’s alpha coefficients were calculated (health and nutrition=0.89, taste=0.72, food preparation=0.77, planning /decision-making=0.64, and convenience=0.63). A confirmatory factor analysis, with 923 new responses provided evidence of an adequate fit …

Food And Culture In Ghana, Une Applied Nutrition Program

All Student-Created Educational Resources

This handout discusses food behavior in Ghana and the influence of Ghanaian culture and religious beliefs on food traditions. Ghanaian staple foods, traditional eating patterns, food preparation, and dining practices are discussed. This handout also includes a brief description of traditional health beliefs and the current food practices of Ghanaians living in the United States.

The Role Of Nr4a1 In Β-Cell Growth And Onset Of Type 2 Diabetes, Adam Wynn, Jeffery Tessem, Ph.D.

Journal of Undergraduate Research

Progression to type 2 diabetes (T2D) includes a loss of functional pancreatic beta cells (β-cells), which are responsible for secreting insulin and maintaining healthy blood sugar levels. Nr4a1 is a gene that has been shown to be involved in fuel utilization in the liver, muscles, and adipose tissues,1, 2, 3, 4 but not much is known about its role in the β-cell and T2D progression. We therefore set out to further define Nr4a1’s role in the β- cell during T2D progression. We hypothesized that the loss of Nr4a1 in the pancreata of mice would result in decreased β-cell maintenance and …

The Evolution Of Food Labeling, University Of New England Applied Nutrition Program

All Student-Created Educational Resources

The infographic displays the timeline pertaining to the regulation created by the Food and Drug Administration to keep food manufacturers accountable for what is labeled on the food they produce. The evolution of nutrition labeling was not solely driven on the decisions made by the government, but also the interests of consumers. The process began in 1969 and has been evolving until present day. As scientists began to uncover the link between diet and food, consumers began to take note. The publishing of both The Surgeon General’s Report on Nutrition and Health and the National Research Council’s report and the …

The Effects Of Hyperlipidemia On Β-Cells, Andrew Barlow, Trevor Lloyd, Mason Poffenbarger, Austin Ricks, Dr. Jeffery Tessem

Journal of Undergraduate Research

Diabetes’ prevalence is increasing at an alarming rate. Normally, insulin-secreting β-cells in the pancreas regulate proper glucose absorption and storage. Type 1 and Type 2 diabetes are characterized by decreased functional β-cell mass and insulin production (1). Diabetes also results in increased circulating glucose and fatty acid levels, which damage and destroy β-cells over time (2). Our study sheds further light on the palmitate and oleate-induced effects of gradually worsening hyperlipidemia and the mechanisms behind those effects; ultimately, promoting investigation into methods by which existing β-cells could be protected from harmful hyperlipidemia.

Nf Κb As A Mediator In Iron Regulation, Erik D. Marchant, Chad Hancock

Journal of Undergraduate Research

Doxorubicin (DOX) is a commonly used chemotherapy drug. Although it is very effective in treating many different types of cancer, it has also been shown to induce oxidative stress in multiple tissues, partially due to severe iron-dysregulation. The effects of DOX have mostly been studied in heart tissue, because DOX has been shown to increase the risk of cardiomyopathy and other heart diseases. Besides causing damage to the heart, DOX has also been shown to contribute to muscle wasting. For this purpose, we decided to investigate how DOX causes iron-dysregulation in C2C12 myotubes, which are immortalized cells from mouse skeletal …