Digital Commons Network^™

Azetukalner, A Novel Kv7 Potassium Channel Opener, In Adults With Major Depressive Disorder: A Randomized Clinical Trial, Noam N Butterfield, Constanza Luzon Rosenblut, Maurizio Fava, Christoph U Correll, Anthony J Rothschild, James W Murrough, Sanjay J Mathew, Gregory N Beatch, Celene Grayson, Cynthia Harden, Jenny Qian, Joe Mcintosh, Rostam Namdari, Christopher Kenney

Staff and Researcher Publications

Importance: Available antidepressants provide inadequate therapeutic responses in many patients with major depressive disorder (MDD), highlighting a substantial unmet need.

Objective: To evaluate the efficacy and safety of azetukalner, a novel, potent KV7 potassium channel opener, in participants with MDD.

Design, setting, and participants: X-NOVA was a multicenter, proof-of-concept, phase 2, randomized, double-blind, parallel-group, placebo-controlled clinical trial that evaluated azetukalner in participants (adults aged ≥18 to ≤65 years) with moderate to severe MDD in a current depressive episode. Participants were enrolled between April 2022 and October 2023, and data analysis occurred from January 2023 to January 2024.

Intervention: Participants were …

Useful Measures Of Adult Attachment And Object Relations In Psychotherapy, Matilde A. Torallas Huerta

Dissertations

This is a literature review of objective and projective measures of attachment and object relations in adults, with the objective of reviewing outstanding research to identify the key factors for adult attachment assessment considered within attachment and object relations theories, what measures of adult attachment styles and dysfunction work best, and to provide key themes of assistance in the measurement of attachment and object relations in adult clients in psychotherapy. Theoretical foundations of attachment and object relations theory are reviewed as well as objective and projective instruments grouped by format. The 10 themes found to be useful in the assessment …

The Effects Of Loving-Kindness Meditation (Lkm) On Relationship Satisfaction In Couple Therapy, Ruimeng Gao

Electronic Theses and Dissertations

This thesis explores the integration of loving-kindness meditation (LKM) into couple therapy sessions and its impact on relationship satisfaction. Meditation, historically rooted in religious practices, has increasingly been adopted in Western therapeutic contexts due to its demonstrated benefits for mental health and interpersonal well-being. Although mindfulness-based interventions have gained popularity in psychotherapy, research specifically examining the use of LKM in couple therapy remains limited. This study investigates whether incorporating LKM into therapy sessions enhances relationship satisfaction compared to standard therapy alone. Couples were randomly assigned to either a control group, which received standard therapy, or an experimental group, which practiced …

Experiences Of Women In The Labour Room: The Untold Story, Emmanuel Dziwornu, Belinda Kpodo, Ophelia Anarfi, Enyonam Afi Adzato, Anita Fafa Dartey

Patient Experience Journal

Background: Childbirth experiences are some of the most sensitive indicators of the utilisation of health facilities. Women who go through the child-birthing process are reported to be faced with a range of experiences. Aim: This study described women's experiences in the labour room. Methods: The study employed a qualitative research approach with a descriptive design. Purposive sampling was used in this study and data saturation was reached after the 18^th participant. In-depth interviews were used to obtain information from recently delivered women. Interviews were audio recorded and transcribed verbatim. Thematic content analysis (TCA) was done and the results were …

Evaluating Referral Rates For Positive Postpartum Depression Screenings At Telehealth And Well-Child Visits: A Scoping Review, Rachel Macklin Barber, Mph, Bsn, Rn, Damaris Amber Brooks, Bsn, Rn, Ashli-Emeria Gary, Bsn, Rn, Margaret Harvey, Phd, Acnp-Bc, Chfn, Kate Fouquier Phd, Aprn, Cnm, Pmh-C, Facnm

Doctor of Nursing Practice Projects

Purpose/Background

Postpartum depression (PPD) affects one in nine women. It has distressing impacts, including behavioral and attachment issues and toveruse of healthcare services. PPD occurs within 4 weeks to 12 months postpartum. A scoping review was conducted to compare referral rates to mental health providers after PPD screenings were conducted via telehealth versus those completed at well-child visits.

Methods

Peer-reviewed articles published within five years before the initial search, beginning September 2022 and ending November 2024, were selected. Articles were sourced from several publications using an online library database with various MeSH terms and Boolean operators. Search results were narrowed …

Use Of Interdisciplinary Rounds For The Identification Of Hospitalized Adults In Need Of Palliative Care, Brenda A. Blunt

Evidence-Based Practice Project Reports

Palliative care (PC) is specialized care that aims to provide relief from the stress and symptoms of living with a serious illness (Center to Advance Palliative Care, 2022). PC services are often underutilized in the hospital, leaving a significant number of patients with unmet needs (Haranis et al, 2023; Kawashima & Evans, 2023; Smith et al, 2019). The purpose of this evidence-based practice project was to improve processes for identifying hospitalized patients for referral to specialty inpatient PC. The intervention involved interdisciplinary rounds (IDR) for adult inpatients on two medical-surgical (MESG) units in an 84-bed community hospital in suburban Milwaukee, …

Exploring The Correlation Between Self-Esteem And Academic Success Among Special Needs Students In Kwara State, Nigeria, Florence Famolu

Jurnal Kajian Bimbingan dan Konseling

Special education has shifted from a position of delivering professional services to students with disabilities to a system that seeks to encompass the broad concept of promoting quality education for students. This study examined the correlation between self-esteem and academic success among special needs students in Kwara State, Nigeria. the study adopted a descriptive survey research type. special needs students in the three local government areas in Ilorin, Ilorin South, East, and West Local Governments Area constituted the total population for this research. The researcher designed questionnaire was entitled: self-esteem as correlate of academic success among special needs students’ questionnaire” …

Fatigue Level Associated With Quality Of Life For Prostate Cancer Patients: Results From The All Of Us Research Program, Hui-Yi Lin, Masuma Mannan, Yu-Wen Chiu, Ya-Hsin Li, Rajasree P. Chowdry, Tung-Sung Tseng

School of Public Health Faculty Publications

BACKGROUND/OBJECTIVES: Prostate cancer (PCa) patients frequently experience extended survivorship, highlighting the importance of quality of life (QoL) in cancer care. QoL has been shown to influence survival and PCa progression. For PCa patients, fatigue is a common issue due to cancer itself or its treatments. However, many QoL studies on PCa patients are limited by small sample sizes in clinic settings and often overlook the impact of fatigue and health-related behaviors. To fill this gap, this study aims to evaluate fatigue associated with QoL and related health measures among PCa patients. METHODS: This study used the All of Us cohort …

Evaluation Of Depression Screening Tools For Utilization In Adolescents: A Scoping Review, Helen Whitaker Bsn, Rn, Jade Bray Bsn, Rn, Tracy Mcclinton Dnp, Aprn, Agacnp-Bc, Hget-C, Ebp-C, Jacqueline Sharp Dnp, Aprn, Pmhp-Bc, Sharon Little Dnp, Fnp-Bc

Doctor of Nursing Practice Projects

Purpose/Background

Anxiety and depression are prevalent mood disorders among the adolescent population with significant impacts on academic performance, social interactions, and mental well-being. With depression rates continuing to rise and suicide among the leading causes of death in adolescents, there is an urgent need for effective screening and intervention. While depression screening is recommended in the primary care setting, many adolescents do not have regular access to healthcare, complicating early identification and treatment. The purpose of this scoping review is to compare the effectiveness of two depression screening tools, the Patient Health Questionnaire (PHQ-9) and the Beck Depression Inventory (BDI), …

Publication Trends In Counselling And Artificial Intelligence: A Bibliometric Analysis, Musthofa Hadi, Rachma Bhakti Utami, Ratnaning Palupi, Farika Nikmah, Eko Boedi Santoso

Jurnal Kajian Bimbingan dan Konseling

Current developments in counseling show significant improvements, especially with the increasingly deeper integration of artificial intelligence (AI). This research focuses on analyzing research development trends in counseling and artificial intelligence, with data collected from Scopus-indexed publications from the beginning of 1982 to 2024. From this period, 470 relevant articles were identified for further analysis. The analysis process is carried out using bibliometric methods with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework, with the help of R-Biblioshiny software, which allows in-depth analysis of patterns and trends in the literature. The analysis results show that this topic has experienced …

Enhancing Schizophrenia Treatment Outcomes: Integrating Cbt With Medication Therapy To Reduce Hospital Readmission, Kamauri Fleming Msn, Rn, Grace Adeniji-Ilesanmi Fnp-Bc, Zillah Anagho Tah Fnp-C, Alex Cook Msn, Rn, Margaret Harvey Phd, Acnp-Bc, Chfn, Sharon Little Dnp, Aprn, Fnp-Bc, Jacqueline Sharp Dnp, Aprn, Pmhnp-Bc

Doctor of Nursing Practice Projects

Purpose/Background Schizophrenia is a chronic mental illness that disrupts cognition, emotion, and social functioning, imposing significant personal and societal burdens. While antipsychotic medications are effective in alleviating psychotic symptoms, they are often associated with side effects, poor adherence, and relapse risk. Cognitive behavioral therapy (CBT) has shown promise as an adjunct to medication, addressing persistent symptoms and improving outcomes. This scoping review examines the integration of CBT with medication therapy to reduce hospital readmissions and improve quality of life for adult patients hospitalized with schizophrenia.

Methods A systematic search of databases, including PubMed, PsycINFO, Embase, and Cochrane Library, was conducted …

Improving Access To Mental Health Care Using Telehealth, Lavern Palmer

Doctor of Nursing Practice Projects

More than half of adults with mental illness in the United States live in mental health deserts—geographic areas with limited access to mental health services and persistent barriers to care. This study investigates the impact of telehealth implementation on patient no-show rates at a rural community clinic in Georgia. The aim was to determine whether the use of telehealth for psychiatric care would decrease the no-show rate of mental health appointments. A retrospective analysis was conducted using patient attendance logs collected 12 weeks before and after the implementation of telehealth services. Quantitative data were analyzed using a Pearson correlation to …

Design Solutions For Common Problems In Senior Living Facilities, Mary Schmidt

Senior Honors Theses

With the aging population of the United States, the prevalence of dementia rises along with its challenges for individuals in long-term care facilities. As cognitive function deteriorates, dementia patients face growing difficulties in performing daily activities. Common issues such as wayfinding, wandering, exit attempts, agitation, and a generally low quality of life plague most dementia patients at long-term care facilities. Design features can improve quality of life, safety, and coherence for residents with dementia at assisted living facilities. This paper examines existing research to present various design strategies that can enhance daily life for dementia patients in long-term care facilities. …

Solution-Focused Brief Group Counseling As An Effort To Reduce Phubbing Behavior Among High School Students, Awalya Siska Pratiwi, Arbin Janu Setiyowati, Im Hambali, Siti Syazwani Zulkuple

Jurnal Kajian Bimbingan dan Konseling

The act of phubbing has been observed to disengage from their surroundings, often finding greater comfort in solitude with their mobile phones. The research objective was to ascertain the efficacy of solution-focused brief group counseling to reduce phubbing behavior in high school students. This study employed a quasi-experimental quantitative research methodology with a pretest-posttest control group design. A total of 10 students, exhibiting a high level of phubbing behavior, were divided into two groups: the experimental group and the control group. The results of the Two-Independent-Sample Test-Mann-Whitney U test are presented in the Asymp .sig column, with a value of …

Rational Emotive Behavior Group Counseling To Reduce Toxic Masculinity In The Patriarchal Culture Of High School Students, Bakhrudin All Habsy, Rukhil Amania, Michael Adeniyi Omoyemiju

Jurnal Kajian Bimbingan dan Konseling

Toxic masculinity is a social construct in patriarchal societies, characterizing male attitudes that dominate and accentuate gender inequality with women in lower positions, influencing detrimental behavioral patterns. This research aims to examine the effectiveness of Rational Emotive Behavior Group Counseling in reducing toxic masculinity behaviors among high school students within the context of patriarchal culture. The study employed an experimental design with a pretest and posttest control group arrangement. From the Toxic masculinity inventory measurements, twelve students with high levels of toxic masculinity characteristics were identified. Subject selection was randomized, with six students in each experimental and control group. Data …

Social Media Usage And Peer Pressure As Predictors Of Substance Abuse Among In-School Adolescents In Kwara State, Nigeria, Mariam Bukola Alwajud-Adewusi, Olayemi Zainab Oduola, Bolanle Ifabiyi

Jurnal Kajian Bimbingan dan Konseling

Substance abuse among youngsters in Nigeria is worrisome. Its consequences include acute, chronic diseases as well as social and psychological ailments. Immediate intervention is essentially paramount to prevent the future of the younger generation. Thus, this study investigated social media usage and peer pressure as predictors of substance abuse among in-school adolescents in Kwara state, Nigeria. The study was a survey research. The population of this study comprised all in-school adolescents in Secondary Schools in Kwara State which estimated at 247,845. The sample size of 403 participated in the study. An instrument entitled “Social Media Usage, Peer Pressure and Substance …

Appreciation Ally, Robert H. Rice, Phoebe Brajdic

Fisher Showcase 2025

Appreciation Ally is an innovative gratitude-focused app developed from evidence-based mental health research.

It uniquely blends visual positivity and reflective journaling, guiding users toward enhanced self-discovery, mood and appreciation.

How Is The Psychological Well-Being Of The Prospective Counselor: The Perma-Profiler, Yessika Nurmasari, Moh. Khoerul Anwar, Muhsin Muhsin, Do Mai Lam

Jurnal Kajian Bimbingan dan Konseling

Well-being is one of the factors that prospective counselors continue to develop themselves and their profession. The research aims to provide an overview of the psychological well-being of prospective counselors. The study used the PERMA-Profiler measurement, distributed to Islamic Counseling Guidance students at UIN Sunan Gunung Djati Bandung. The data were analyzed by quantitative descriptive with simple random sampling. The attachment indicator (E) is the largest at 7.48, followed by the positive emotion indicator (P) at 7.44, the meaningfulness indicator (M) with a score of 7.39, the relationship indicator ® with a score of 7.21, the achievement indicator (A) with …

Factors Influence Homeless People’S Psychological Well-Being And Suicidal Ideation, Pi-Ming Yeh

Epsilon Sigma at-Large Research Conference

Introduction/Significance: About 582,462 individuals are experiencing homelessness in America. Homelessness is devastating, regardless of age. But for children, it can have serious physical, emotional, and psychological implications.

Purpose: The purpose of this study was to examine the influences of spiritual well-being, coping strategies, family interaction, and personality on psychological well-being, and suicidal ideation among people with homelessness.

Methods: Sixty people with homelessness were recruited in the Eastern Tennessee Downtown Day Center, USA. IRB was approved. This was a cross-sectional descriptive research design. Questionnaires were used to do data collection. SPSS 28.0 was used to do the data analysis. Descriptive …

Inside The Mad Mind: Medical Ethics In 19th Century Fiction, Danielle Dentremont

College Honors Program

The professionalization of medicine in mid-to-late 19th century America and Britain corresponded with heightened critical scrutiny of the ethics of doctor-patient relationships in contemporary fiction. With ethics frameworks of the century focused primarily on good fellowship between practitioners, it was difficult to charge practitioners with bad ethics. Yet, the broader debates of vivisection and women’s rights brought to light power imbalances between men and women that novelists began to suggest were present in medicine as well. Wilkie Collins’ Heart and Science weighs in on the danger of the doctor-scientist encroaching on women’s rights with the suggestion that women will be …

The Use Of Person-Centered Language In Scientific Research Articles Focused On Psychosis, Zach Monahan, Tanner Stone, Vinay Swami, Kelly Dunn, Micah Hartwell

Journal of Patient-Centered Research and Reviews

Purpose: Societal stigma of psychosis leads to delayed treatment for individuals experiencing early symptoms, for fear of being labeled “crazy” or “psychotic.” Delayed treatment can worsen the prognosis of individuals with psychosis. Proper adherence to person-centered language (PCL) guidelines can curb the widely held stigmatized preconceptions about psychotic conditions.

Methods: Our meta-epidemiological analysis began with a systematic search of literature in PubMed discussing psychosis from 2020-2022. From the 14,522 results, we randomly selected 500 articles in journals with at least 20 articles on psychosis (n = 9,775), of which 241 articles met the inclusion criteria. These papers were screened for …

Implementing A Six-Week Intermodal Expressive Arts Therapy Program For Individuals With Parkinson’S Disease: A Practitioner-Based Perspective, Sara Adams

Expressive Therapies Theses

Parkinson’s Disease (PD) is a neurodegenerative disorder that affects motor function, emotional well-being, and social engagement. While traditional rehabilitation approaches emphasize physical therapy and medication management, emerging research highlights the potential of creative arts therapies in addressing the multidimensional challenges of PD. This thesis explores the implementation of an intermodal expressive arts therapy intervention designed to support individuals with PD through dance, music, drama, and visual arts. Conducted over six weeks within a community support group in Nova Scotia, the program included guided visualization, Brain Dance exercises, creative movement, drama-based activities, and reflective art-making. A qualitative, practitioner-based method was used, …

Animal-Assisted Therapy With Children In Hospitals And Schools: A Systematized Review, Tantine Kendig

LSU Master's Theses

It has been demonstrated that animals can offer humans significant health benefits. Animal-assisted therapy (AAT) is a growing form of therapy used in various settings to enhance the health of children, encompassing both physical and mental wellness. The challenges of hospitalization and the school environment have been shown to pose different challenges for children, such as an increase in anxiety, stress, depression, and others that have the potential to affect their mental, physical, emotional, and social well-being. This study aimed to assess the effectiveness of animal-assisted therapy, specifically dog-assisted therapy, on children in hospital and school settings by conducting a …

Ua12/2/1 College Heights Herald, Vol. 100, No. 3, Wku Student Affairs

WKU Administration Documents

Magazine edition of the College Heights Herald for the period February 17 - April 20, 2025.

• Wilborn, Price. You Matter & You Are Not Alone
• Smith, Kane. Peggy Crowe Reflects on Counseling Center in Face of Staff Shortages
• Stafford, Hallie. Help with Horses – New Beginnings Therapeutic Horse Riding
• Hawkins, Kaylee. How a WKU Professor Helps Improve Student Mental Health – Jay Gabbard, National Alliance on Mental Illness Recovery Support Group
• McMahon, Jake. More Than a Coach – Brent Chumbley, Track & Field
• Simpson, Libby. WKU’s American Foundation for Suicide Prevention Brings Mental Health Into the Light
• Hardesty, Emma. Trans …

Psychological Treatment Behind The Walls:Insights From The Inside, Rogelio Serrano

Psychology Division Scholarship

Repeated eras of mass incarceration, criminalization of marginalized communities, and substance use policies have created a revolving door of justice involved populations. The ever-increasing prison population has repeatedly become the largest contingency of mental health clientele for an overburdened mental health system. Those who work with formerly incarcerated individuals in the community often don’t know the unique set of challenges faced by practitioners within the system. Increased understanding and coordination of care can offer opportunities for sustained recovery and reduced levels of recidivism. In this presentation participants will learn about the unique insights on mental health treatment that can be …

Staying Safe When Taking Prescription Opioids, Aaron Hunt, Gabriela Murza, Amy May, Jenna Hawks, Alyssa Ferrin

All Current Publications

Prescription opioids, such as oxycodone, morphine, codeine, and hydrocodone, are often used for short-term pain management, and it is important to know how to keep yourself safe when taking opioids prescribed by a doctor. This fact sheet reviews what opioids are, how they work in the body, and how people become dependent on or overdose on opioids. It also offers how to limit your risk of dependence and suggests alternative pain management options.

Addressing Pain Management Postoperatively From A Multimodal Approach In Response To The Opioid Epidemic, Victoria Pascoe

Best Integrated Writing

This review article explores the four-wave opioid epidemic across the United States and the postsurgical multimodal pain management approaches being implemented to help combat it. Breaking down the mechanistic approach to pain in the form of opioid-alternative analgesics, cryotherapeutic techniques, cognitive approaches, and more, this paper offers insight into how pain can be managed outside of the historical approach, while also exploring the future directions of the field as physicians and researchers alike search for ways to offer more comfort and quality of life to the patients who walk through their clinic doors.

Biopsychosocial-Based Exercise Model For Rheumatic Diseases Via Telerehabilitation: A Case Series With A One Year Follow Up, Nazlı Elif Nacar, Nur Banu Karaca, Zeynep Irem Bulut, Erkin Oguz Sarı, Senem Bulut, Yavuz Yakut, Sevim Oksüz, Sedat Kiraz, Edibe Unal

Internet Journal of Allied Health Sciences and Practice

Purpose: This study aims to examine the sustainability of the biopsychosocial exercise performed by telerehabilitation on individuals with rheumatic disease, with and without supervision, and investigate the effect of the biopsychosocial-based exercise model on biopsychosocial status, general health status, and anxiety-depression levels of individuals. Method: Twenty patients with rheumatic diseases performed a biopsychosocial-based exercise model Cognitive Exercise Therapy Approach via telerehabilitation with physiotherapist-supervised and unsupervised exercises who continued for three sessions per week for 12 months. Outcome measures were Health Assessment Questionnaire, Hospital Anxiety and Depression Scale, and Cognitive Exercise Therapy Approach -Biopsychosocial Questionnaire. Patients were assessed at baseline, 3rd, …

Comparison Of Cognitive Functions, Sleep Quality, Emotional State, Balance And Physical Activity Levels Of University Students According To Academic Success, Sevim Oksuz, Ozde Depreli, Aytül Ozdil, Gozde Iyigun, Ender Angın, Betül Fatma Bilgin, Ayşen Karaman

Internet Journal of Allied Health Sciences and Practice

Purpose: This study was planned to compare the level of attention, dual-task abilities, sleep quality, emotional state (anxiety, depression, stress), dynamic balance, and physical activity level in low and high-academic success university students. Method: A total of 134 international undergraduate students between the age of 18 and 25 (low academic success group n=67, high academic success group n=67) were recruited for this study. The Trail Making Test (TMT) – A and B was used for attention assessment, the TMT While Walking – A and B was utilized for dual-task performance, the Pittsburgh Sleep Quality Index (PSQI) was utilized to assess …

Evaluation Of An Occupational Therapy Intervention In Prisons To Prepare Incarcerated Individuals For Successful Community Reentry, Dalenna Bellum, Sue Dahl-Popolizio, R. Curtis Bay, Angela Zhu, Jeremiah Fine, Bruce Kotter, Abbey Glenn, Rebecca L. Wolf

The Open Journal of Occupational Therapy

Background: Literature suggests that to reduce recidivism and facilitate successful community reintegration, incarcerated individuals need life skills training before release. This study evaluated the effectiveness of such an occupational therapy (OT) program.

Methods: We provided and evaluated a 12-session pilot OT program with incarcerated men providing life skills education for community reentry. We used forced-choice and open-ended questions with pre/post Employee Self-Assessment Tool (ESAT), assessing interpersonal, self-management, analytical skills, and skills used in an organization, and Life Skills Program Daily Surveys (LSDS) assessing participants’ perceptions of program effectiveness.

Results: Ninety-three of the residents participated; 69 completed …