Digital Commons Network^™

The Polymerized Protein Response (Ppr) Is Activated By Genetic Variants That Polymerize In The Er And Is Mediated By Nfκbp50, Admire Munanairi, David A Rudnick, Jiansheng Huang, David H Perlmutter

2020-Current year OA Pubs

In previous studies we have shown that accumulation of the polymerogenic variant ATZ that causes α1-antitrypsin deficiency (ATD) activates NFκB DNA binding. Here we discovered that this response, which we are naming the polymerized protein response (PPR), is characterized by NFκB p50 homodimers, distinct from the p50/p65 heterodimers in the canonical NFκB inflammatory response and the unfolded protein response (UPR). The PPR is also activated by other disease associated variants that polymerize in the ER whereas disease-associated variants that do not form polymers activate p50/p65 heterodimers and UPR. The PPR elicits a unique gene expression profile, including changes that stabilize …

How Survivors Of Exploitation Who Use Drugs Navigate Systems Of Care: An Analysis Of Survivor Insights Using The Intersectional Risk Environment, Theresa Anasti, Hilary Thibodeau, Nathaniel A Dell, Kathleen Preble, Lauren Grimes, Lindsay B Gezinski

2020-Current year OA Pubs

BACKGROUND: Drug-related risks such as adverse health outcomes, overdose, and violent victimization vary across populations due to the marginalization of identities, structural inequities, and differing environments. Discrimination and criminalization exacerbate drug-related risks specifically for survivors of sexual exploitation who use drugs. This study aims to understand how survivors who are not currently utilizing intensive treatment services perceive their risk environment, including available resources, and identify possible mechanisms to address health equity. Emphasizing the role of harm reduction and the expertise of lived experience, this paper encourages innovative approaches to supporting survivors.

METHODS: A research team conducted seventeen semi-structured interviews with …

Embedding Social Determinants Of Health Into Maternal Simulation Scenarios: Enhancing Nursing Staff Awareness Of Equity-Based Education, Sherina Evans

Doctor of Nursing Practice Projects

Despite growing evidence emphasizing the importance in addressing disparities in maternal health outcomes, maternal health simulations often lack integration of social determinants of health (SDOH) and cultural considerations. The purpose of this Doctor of Nursing Practice quality improvement project was to enhance nursing faculty cultural awareness through simulation scenarios that incorporate SDOH and culturally responsive elements. This project was guided by Lewin’s Change Theory and the Jeffries Simulation Framework. The aim was to strengthen faculty awareness and skills to support the development of culturally inclusive simulation experiences. Descriptive statistics were utilized to analyze results which was a limitation. Nursing faculty …

An Evaluation Of Total Navicular Implants: A Scoping Review, James Mcclure Hughes, Nicholas Belardo Obias, Amanda Killeen

School of Podiatric Medicine - Student Research

The aim of this study is to determine the efficacy and safety profile of total navicular implants based on current literature.

Navicular insults such as high-energy trauma, osteonecrosis, and Muller-Weiss syndrome may result in avascular necrosis or a critical sized bone defect, conditions that are highly difficult to manage given current treatment modalities. Total navicular implants may offer a solution to these problems. While 3D printing of implants remains investigational, its use in highly individualized cases involving the talus has had promising results with conditions like avascular necrosis, tumors, trauma, and arthritis. The navicular is unique in its attachments to …

A Novel Guide‑Free Internal Device Fixation For Transverse Tri‑Planar Distal Metatarsal Osteotomy: A Retrospective Review​, Maya D. Kaafarani, Brittney White, Graham A. Hamilton, Shannon M. Rush

School of Podiatric Medicine - Student Research

Introduction: Minimally invasive surgery (MIS) for bunion correction has gained popularity due to favorable outcomes and reduced recovery times. However, most MIS techniques rely on commercial instrumentation for osteotomy, reduction, and fixation. This retrospective study evaluates patients treated with a novel tri-planar distal metatarsal osteotomy performed without specialized MIS guides, using only standard surgical tools and a novel device.

Methods: A retrospective review was conducted on 28 patients (31 procedures, including 3 bilateral cases) who underwent MIS bunion correction from 2021 to 2024. The technique involved a 2–3 cm medial incision, transverse osteotomy at the distal surgical neck of the …

Improving Monitoring And Documentation Of Long-Acting Injectable Antipsychotic Adherence In Patients With Schizophrenia Through Staff Education And Refill History Review, Stacy Ann Bruce

Doctor of Nursing Practice Projects

Schizophrenia is a chronic psychiatric disorder associated with relapse, hospitalization, and poor outcomes when medication adherence is suboptimal. Nonadherence increases morbidity and healthcare utilization (World Health Organization, 2022; Zhao et al., 2025). Long-acting injectable (LAI) antipsychotics improve adherence and reduce hospitalization, but inconsistent monitoring and documentation in outpatient settings hinder early identification of missed doses (Lieslehto et al., 2022). This Doctor of Nursing Practice (DNP) quality improvement project aimed to evaluate whether staff education and structured refill-monitoring processes improve identification and documentation of nonadherence to LAI antipsychotics. Using Kotter’s Change Management Model and the Plan-Do-Study-Act framework, the project focused on …

Quality Improvement Project: Emergency Preparedness In Urgent Care: Impacting Competency Among Medical Assistants, Sarah Pettyjohn

Doctor of Nursing Practice Projects

Urgent care settings present significant challenges, including limited staffing and resources, unpredictable patient acuity, and training deficiencies. These factors contribute to a competency gap among medical assistants, limiting their ability to recognize and respond to medical emergencies. The purpose of this quality improvement project is to impact emergency medical preparedness through a formal educational intervention. Grounded in Lewin’s Change Model and the Kirkpatrick Model, the project aims to improve emergency medical competency, consistent with evidence supporting structured training approaches. Using American Heart Association guidelines, medical assistants participated in a six-week educational program implemented through the Plan-Do-Study-Act framework, with assessments administered …

Intouch Week Of April 27, 2026, New York Medical College

InTouch

• Tracey Milligan, M.D., FAAN, and Sarah Parauda, M.D., Honored on National Stage with Top Neurology Awards
• White Coat Ceremony Ushers SLP Class of 2027 into Clinical Training
• D.P.T. Class of 2028 Steps into Clinical Education
• SOM Class of 2028 Marks Milestone as Clinical Training Begins
• NYMC Celebrates Earth Day with Campus Sustainability Initiatives
• A Pawsitive Break for the NYMC Community
• Student Spotlight: Ashley Abing-Mesropyan Follows a Path Towards Meaningful Care

From Charcuterie Board To Clinical Ward: Pediococcus Pentosaceus As An Emerging Wound Pathogen - A Scoping Review, Jessica Sima, Mariana Rodriguez, Stephanie Campbell, Amanda Killeen

School of Podiatric Medicine - Student Research

Currently, there are 12 known species of Pediococcus, with P. Acidilactici and P. pentosaceus being the most well-known. P. pentosaceus is a Gram-positive, lactic acid bacterium, and is most often recognized for its wide usage as a probiotic and fermenter of wines and cheeses. It is also studied for its anti-inflammatory effects and antimicrobial properties against many common pathogens, such as Salmonella, Clostridium difficile, E.coli, etc.  However, the Pediococcus species can be an opportunistic pathogen in immunocompromised patients, and its resistance to glycopeptides and tetracycline limits treatment options.

We conducted a scoping review using Google Scholar and PubMed with the …

Improving Identification And Referral Of Xylazine‑Associated Wounds In Homeless Healthcare, Ramon A. Gambino

Doctor of Nursing Practice Scholarly Projects

Background: Xylazine-adulterated fentanyl is linked to distinctive necrotic wounds and complex care needs in unsheltered populations. This quality improvement (QI) project implemented a brief survey and referral log at Albuquerque Health Care for the Homeless (AHCH) to track suspected xylazine-associated wounds and referrals to advanced care. Methods: Final data were exported from Qualtrics, cleaned to retain finished responses, standardized categories, and de-identified. The analytic sample included 18 encounters. Results: Results showed that 55.6% (n = 10) documented suspected xylazine-associated wounds; 5.6% (n = 1) reported no suspicion; 38.9% (n = 7) were uncertain. Referrals were rarely documented overall at AHCH …

Cross-Sectional Associations Of Metabolically Healthy Obesity, Lifestyle Factors, And Steatotic Liver Disease In Adults From The Fels Longitudinal Study, Ariana L. Garza, Audrey C. Choh, John Blangero, Cici X. Bauer, Stefan A. Czerwinski, Miryoung Lee

School of Medicine Publications

Objective: To examine the associations of metabolic health and obesity phenotypes with liver fat accumulation and hepatic steatosis in adults. Methods: We analyzed 676 non-Hispanic white adults (18–95 years; 55.8% female) from the Fels Longitudinal Study using a cross-sectional design. Participants were classified into metabolically healthy normal weight (MHNW), metabolically healthy obesity (MHO), metabolically unhealthy normal weight (MUNW), and metabolically unhealthy obesity (MUO) phenotypes. Metabolically unhealthy status was defined as the presence of ≥1 metabolic dysfunction, consistent with prior epidemiological definitions; secondary analyses using ≥2 were also performed. Obesity was defined using DXA-derived body fat percentage. Liver fat (%) was …

Olanzapine-Based Vs Neurokinin-1 Receptor Antagonist Antiemetic Regimens In Highly Emetogenic Chemotherapy: Systematic Review And Meta-Analysis Of Efficacy And Safety, Advaitha Mv, Nikhilesh Anand, Biacin Babu, Ayoola Awosika, Uttam Udayan, Jacqueline Mendoza, Alissa Lopez, Brahmaiahchari Rangachari, Sabyasachi Maity, Bharathi Gadad

School of Medicine Publications

Background: Chemotherapy-induced nausea and vomiting is common in patients who receive highly emetogenic chemotherapy (HEC). Olanzapine acts on multiple neurotransmitters and effectively reduces delayed-phase nausea.

Aim: To compare the safety and efficacy of olanzapine-based vs neurokinin-1 receptor antagonist-based antiemetic regimens in adults receiving HEC.

Methods: This review followed Preferred Reporting Items for Systematic Reviews and Meta-analyses 2020 guidelines and searched various databases like PubMed, Scopus, etc., between 2020-2025. 14 studies were included in the systematic review with 11 meeting the criteria for meta-analysis. Primary outcomes were complete response (no vomiting, no rescue medication) and nausea control during acute (0-24 hours), …

Peace Counseling For Grief Recovery: A Study Of Its Effectiveness In Families Of Coal Mine Drowning Victims In East Kalimantan, Siti Nurul Hajirotul Qudsiyah, Wahyu Nanda Eka Saputra, Hardi Santosa

Buletin Konseling Inovatif

This study examines the psychological impact of prolonged grief among families of coal mining pit drowning victims and evaluates the effectiveness of peace counseling as an intervention strategy. The study aims to assess whether structured counseling can reduce grief loss and support adaptive psychological adjustment. A quantitative quasi-experimental approach was employed using a Single Subject Research (SSR) A–B–A design involving two participants who were mothers of the victims. Data were collected using the Grief Losing Scale administered repeatedly across baseline (A1), intervention (B), and post-intervention (A2) phases. The intervention consisted of six structured peace counseling sessions focusing on emotional processing, …

Literature Review: Trauma Care For Psychological Strengthening Of Adolescent Survivors Of Sexual Violence, Ahmad Tubagus Darodjat, Otto Fajarianto, Awalya Siska Pratiwi

Buletin Konseling Inovatif

Sexual violence, both physically and psychologically, can be a traumatic stressor that triggers trauma in an individual's life. Trauma is a common condition that has a complex impact on an individual's life. This study aims to collect and analyze articles related to trauma care for psychological strengthening of adolescent survivors of sexual violence. The method used is a literature review. The author summarizes, makes a critical and in-depth analysis of previous literature. Based on the articles collected, it was found that sexual violence can leave a severe traumatic impact on victims. Victims may experience stress due to traumatic events, both …

2026 - The Thirtieth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the 30th Annual Symposium of Student Scholars, held on April 22-24, 2026. Includes abstracts from the presentations and posters.

Nurses’ Attitudes Toward Physical Examination, Nazan Çaylı, Cansu Nirgiz, Merve Kıymaç Sarı

Makara Journal of Health Research

Background: This descriptive, cross-sectional study was conducted to determine the attitudes of nurses working in clinical settings toward conducting physical examinations.

Methods: The sample surveyed consisted of 364 nurses currently working at 14 branches of a private hospital with facilities in seven cities, who participated voluntarily. Data was collected online via a survey created through Google Forms, applying descriptive characteristics form and the Physical Examination Attitude and Practice Scale in Nursing. The data were analyzed using the Mann–Whitney U test, Kruskal–Wallis test, Spearman’s rank-order correlation coefficient, and multiple regression analysis.

Results: It was found that nurses had …

From Novice To Effective: Strengthening Clinical Education In Nursing, Stephanie Campbell

Doctor of Nursing Practice Projects

The professional transition from clinician to educator is often complicated by a lack of formal training and professional development. This gap in training and support compromises the delivery of nursing education and leads to feelings of inadequacy, diminished confidence, and higher rates of attrition. This quality improvement (QI) project seeks to improve the quality of clinical education by evaluating the impact of a structured onboarding process on a novice nurse educator’s self-efficacy and perceived support. Guided by Lewin’s Change Theory and Bandura’s Social Cognitive Theory, the project aims to enhance the onboarding process for novice nurse educators. The Find, Organize, …

The Big Five Personality Traits And Perceptions Of Generative Ai In Higher Education: A Canonical Correlation Analysis For Sustainable Digital Education, Mei Jiang, Shifang Tang, Qingwei Wang

Faculty Publications

The purpose of this study was to examine the multivariate relationship between college students’ Big Five personality traits and their perceptions of generative artificial intelligence (AI). Guided by sustainable digital education and expectancy-value theory, this study investigated whether personality profiles were associated with students’ knowledge of AI, attainment value, intrinsic value, utility value, perceived cost, and intention to use AI. Using a cross-sectional survey design, data were collected from 375 students enrolled at a Southwestern doctoral-granting public university. Participants completed an adapted measure of generative AI perceptions and the Big Five Inventory, and canonical correlation analysis (CCA) was conducted to …

Improving Cultural Competence Among Healthcare Professionals Through A Targeted Staff Training Program, Oyindamola Akinkugbe

Doctor of Nursing Practice Projects

Limited culturally competent care for Hispanic patients worsens existing health disparities, creates misunderstandings, leads to poor health outcomes, and reduces satisfaction with the quality of care. In an outpatient clinic, more than 70% of patients are Hispanic, yet healthcare providers reported a lack of confidence in caring for culturally diverse patients. Extensive literature supports staff training to improve provider cultural competence, but implementation remains inconsistent across healthcare settings. This quality improvement project addressed this gap by implementing a targeted staff training program grounded in the Culturally and Linguistically Appropriate Services (CLAS) in Nursing framework. The purpose of this project was …

Enhancing Shared Decision-Making In Mental Health Care: A Quality Improvement Initiative, Joanna L. Hysler

Doctor of Nursing Practice Projects

Shared decision-making (SDM) is an evidence-based approach that enhances patient engagement, treatment adherence, and clinical outcomes in psychiatric care. Despite strong support in the literature, SDM remains inconsistently implemented in mental health settings due to limited provider training, time constraints, and organizational barriers. The purpose of this Doctor of Nursing Practice quality improvement project was to implement and evaluate an educational intervention designed to improve SDM utilization and provider confidence within a private outpatient psychiatric practice. The project was guided primarily by the Plan-Do-Study-Act framework to support structured practice change, with Lewin’s Change Theory providing additional conceptual support. The intervention …

Quality Improvement Project: Reimplementation Of Bedside Reporting, Veronicah Banga

Doctor of Nursing Practice Projects

Communication breakdown during nursing shift handoffs is a major patient safety challenge in healthcare today. At the project site, 85% of handovers occurred at the central nursing station, and most staff nurses expressed dissatisfaction with the quality of the bedside reporting. In psychiatric nursing, unique barriers exist that make bedside reporting challenging, including patient confidentiality and an individual's diagnosis. Such barriers eroded bedside reporting (BSR) over time, leading to measurable safety risks and nursing dissatisfaction. The purpose of this quality improvement project was to reintroduce bedside handoffs using the Situation, Background, Assessment, and Recommendation (SBAR) framework and to maintain BSR …

Eeg Studies Of Pre-Stimulus Activity During Turn-Taking In Naturalistic Conversation, Seyedmohamadreza Manzourolajdad

Student Works (2020-2029)

This study integrates conversational analysis principles and neural activity to investigate natural cognition and examine event-related brain changes. A wireless electroencephalography (EEG) device was used in an ecological validity setting to analyse pre-stimulus brain activity preceding conversational turns. This study aims to identify aspects of the conversation that reflect its naturalness in the aspect of listening and the corresponding brain activity by analysing the signals before and after a turn in a conversation. This research contributes to an ecologically valid understanding of natural conversation as a social action that enables seamless communication. Seven Malaysian participants (aged 19–22, M=20.46) engaged in …

Food Reintroduction After Negative Ofcs In Pediatrics: Dietary Frequency And Caregiver Attitudes, Olivia Pietrantozzi

Honors Projects

Food allergies in pediatric populations have been gradually increasing in prevalence and present significant nutritional risks requiring strict dietary management and psychosocial challenges. Oral food challenges (OFCs) serve as a gold standard in diagnosing food allergies and determining whether allergenic foods can be safely reintroduced to an individual's diet. However, caregivers of children may still experience anxiety and barriers that delay the reintroduction of foods, which can limit diet diversity and increase the child's risk of future allergy development. This study looked to evaluate the dietary frequency of allergenic food reintroduction following negative OFCs, as well as to assess changes …

Association Between Maternal Factors And Stunting Based On The Indonesia Family Life Survey 5 (Ifls-5), Charissa Otniel Sukamto, Siti Nur Fatimah, Noormarina Indraswari

Makara Journal of Health Research

Background: Stunting remains a major issue in Indonesia. Maternal factors during pregnancy are one of the key determinants in preventing stunting. This study aimed to analyze the association between maternal history during pregnancy (age, height, parity, and inter-pregnancy interval) and stunting, with a comparison between urban and rural areas.

Methods: This analytical cross-sectional study used data from 3,639 children aged 1-5 years old from the household survey of Indonesia Family Life Survey 5, conducted between late October 2014 and August 2015 within 13 provinces in Indonesia. Data was analyzed using chi-square and binary logistic regression methods.

Results: …

Self-Efficacy And Health Promotion: The Roles Of Family Health And Health Literacy, Müjdat Yeşildal, Yunus Emre Öztürk

Makara Journal of Health Research

Background: Chronic noncommunicable diseases are the leading causes of death globally and in Türkiye, emphasizing the need to explore how individual, familial, and informational factors shape health-promoting behaviors. This study examined whether family health and health literacy sequentially mediate the relationship between general self-efficacy and health-promoting behaviors among adults in Türkiye.

Methods: A cross-sectional correlational study was conducted with 1,240 adults in Konya Province, Türkiye, between November and December 2022. Participants completed the Turkish versions of the General Self-Efficacy, Family Health, Health Literacy, and Health-Promoting and Protective Behaviors Scales. Data were analyzed using descriptive statistics, Pearson correlation, and …

Examining The Psychometric Properties Of The Big Three Perfectionism Scale–Short Form (Btps-Sf) Among Malaysian Chinese Students At A Private University, Kam-Fong Lee, Ashraf Sadat Ahadzadeh, Shin Ling Wu

Makara Journal of Health Research

Background: Perfectionism is increasingly prevalent among young adults and is a significant predictor of pathological and behavioral outcomes. Despite its relevance, validated and reliable measures of perfectionism tailored to university students, particularly within the Malaysian cultural and academic context, are lacking. This study addresses this gap by examining the psychometric properties of the BTPS-SF among Chinese students at a private university in Malaysia.

Methods: Data were collected using a cross-sectional design with convenience and snowball sampling from 380 students aged 18–25 years, predominantly from a Chinese student population.

Results: The results of the exploratory factor analysis, conducted …

Organizational Governance Capacity And Organizational Resilience In Hospitals: A Cross-Sectional Study, Leyla Afşar, Selim Yazıcı

Makara Journal of Health Research

Background: This study aims to examine the relationship between organizational governance capacity (OGC) and organizational resilience (OR) in hospitals, with a focus on cross-institutional differences.

Methods: A cross-sectional study was conducted among 1,143 employees from six hospital types in Istanbul, including university, Ministry of Health (state, training and research, and city), and private hospitals. Validated scales were used to measure OGC and OR. Data were analyzed using descriptive statistics, nonparametric tests, and structural equation modeling (SEM) to assess the relationships between these dimensions.

Results: Private hospitals demonstrated the highest levels of both OGC and OR (70%), followed …

Knowledge Of Parents And Guardians Of Computed Tomography Examinations And Radiation Risks In Children In Malaysia, Nur Maisarah Ali Wahab, Nur Hamizah Mohd Zainudin

Makara Journal of Health Research

Background: Early exposure to computed tomography (CT) imaging during childhood increases cancer risk, emphasizing the critical need to minimize unnecessary imaging in pediatric patients. This study aimed to assess parents and guardians’ knowledge about CT examinations and their associated risk following pediatric CT.

Methods: A cross-sectional survey was conducted among parents and guardians who accompanied their children to a private hospital radiology department for CT examinations. The survey enquired about their socio-demographic, knowledge of CT examinations, and their radiation risks. Data were analyzed using descriptive analysis and the Kruskal-Wallis test.

Results: A total of 144 responses were …

Frailty And Fall Risk In Older Adults With Type 2 Diabetes: A Cross-Sectional Study, Hatice Yılmaz, Nazmiye Çıray

Makara Journal of Health Research

Background: This study aimed to examine the effect of frailty on the risk of falls in older adults aged 65 years with type 2 diabetes.

Methods: The study is cross-sectional and correlational. The sample included 146 individuals aged 65 years who had type 2 diabetes and visited the internal medicine outpatient clinic of a state hospital in Türkiye. The participants were assessed based on a personal information form, the Mini-Mental State Examination, Edmonton Frail Scale, Morse Fall Scale, and Katz Index of Independence in Activities of Daily Living. IBM SPSS Statistics version 22.0 was used for data analysis. …

Examination Of Health-Seeking Behavior In Individuals With Chronic Diseases, Dilan Aktepe Coşar, Hatice Demirağ, Aynur Cin

Makara Journal of Health Research

Background: Chronic illnesses are long-term, noncommunicable diseases that significantly affect daily life. In addition to physical symptoms, they can reduce quality of life by causing psychological effects such as anxiety and depression. Patients often seek health information to better manage their condition.

Methods: This study aimed to examine the level of health information-seeking behavior among individuals with chronic diseases and the factors influencing this behavior. The sample group for this descriptive study consisted of 306 individuals with chronic illnesses who visited X Hospital in northeastern Türkiye between April 1, 2024, and February 1, 2025. All individuals completed a …