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Unidirectional Calcium And Nucleotide Fluxes In Sarcoplasmic Reticulum. I. Interpretation Of Flux Ratios For Different Reaction Schemes, J. J. Feher

Physiology and Biophysics Publications and Presentations

The relation between unidirectional calcium and nucleotide fluxes was examined for different ATPase reaction schemes of the sarcoplasmic reticulum. The schemes considered differed in the order of sorption and desorption of calcium, ATP, and ADP. The results suggest that the theoretical relation between calcium and nucleotide fluxes depends on the reaction scheme and that experimental measurements can distinguish among them. The results obtained are generally valid and do not depend on assumptions of equilibrium or pseudoequilibrium between intermediate states of the pump.

Potential And K+ Activity In Skinned Muscle Fibers. Evidence Against A Simple Donnan Equilibrium, R.E. Godt, C.M. Baumgarten

Physiology and Biophysics Publications and Presentations

ABSTRACT

It has been suggested that potentials measured with conventional microelectrodes in chemically or mechanically skinned muscle fibers arise from a Donnan equilibrium due to myofilament fixed charges. This hypothesis was tested in mechanically skinned frog (Rana pipiens) semitendinosus fibers by measuring the distribution potential (Ed) between fiber and bath with 3 M KCI-filled microelectrodes and the K+ activity gradient (a'K/a) with K+ ion-selective microelectrodes (KISE). If skinned fibers are a Donnan system, Ed should become more positive as pH is decreased, altering the fixed charge on the myofilaments. Consistent with this expectation, Ed was -4.4, -0.6, and +4.8 mV …

Undirectional Calcium And Nucleotide Fluxes In Cardiac Sarcoplasmic Reticulum. Ii. Experimental Results, J. J. Feher, F. N. Briggs

Physiology and Biophysics Publications and Presentations

Unidirectional calcium influx and efflux were evaluated in cardiac sarcoplasmic reticulum (SR) by 45Ca-"0Ca exchange at steady state calcium uptake in the absence of calcium precipitating anions. Calcium efflux was partitioned into a pump-mediated efflux and a parallel passive efflux by separately measuring passive efflux referable to the steady state. Unidirectional and net ATP-ADP fluxes were measured using [3H]-ATP -- ADP and [3H]- ADP -- ATP exchanges. Methods are presented that take into account changing specific activities and sizes of the nucleotide pools during the measurement of nucleotide fluxes. The contribution of competent and incompetent vesicles to the unidirectional and …

Effect Of Membrane Filtration Of Antimalarial Drug Solutions On In Vitro Activity Against Plasmodium Falciparum, J. Kevin Baird, C. Lambros

United States Public Health Resources

Antimalarial activities ofchloroquine, mefloquine, amodiaquine, and quinine in vitro against Plasmodium falciparum were diminished as a consequence ofmembranefiltration. Filtered drug solutions gave ID₅₀ values up to 25-fold greater than those of non-filtered (ethanol-sterilized) drug solutions. Loss ofactivity byfiltration was overcome by increasing the drug concentration prior to filtration. Water solutions filtered through Millex-GSfilter units consistently showed an absorbance maximum at 277 nm, accompanied by a lesser peak at 225 nm. Water filtrates from Nucleopore and Millex-G Vfilters showed no absorbance at 277 nm and only slight absorbance was evidentfor the Gelmanfilter unit. Activity losses were attributed to extractable contaminating …

The University Of Health Sciences Journal: 1984 Edition, University Of Health Sciences College Of Osteopathic Medicine, James F. Ryan

University of Health Sciences Journal (1981-1985)

Contents: Finding an Internship -- Academics: Maintaining the Standards of Education -- Building the Foundation of Osteopathic Medicine -- UHS/COM Board of Trustees -- Recording the Impact of DRG's -- Commencement 1984 -- Breaking the Stereotype -- Alumni Album -- The Faces of 1984 at UHS -- COMments -- People -- In Memoriam.

The Bush Tick, R B. Besier

Journal of the Department of Agriculture, Western Australia, Series 4

A newly discovered livestock parasite has focused attention on farms in the Walpole district in the south-west of Western Australia. Ticks submitted to the Department of Agriculture in December 983 were identified as the bush tick, Haemaphysalis longicornis. An intensive campaign to locate areas of infestation and to limit spread was started in January 1984.

The bush tick is a pest of livestock in some areas of New South Wales and Queensland. It is important in a narrow coastal strip from Sydney to Brisbane where total summer rainfall can exceed 1000 mm. In this area heavy tick infestation causes …

Protecting Off-Shears Sheep In Adverse Weather, T M. Ellis

Journal of the Department of Agriculture, Western Australia, Series 4

In January 2982 in the Narrogin-Darkan area of Western Australia, about 14,500 sheep up to 40 days off-shears died after a 48-hour period of heavy soaking rain that followed a thunderstorm three days previously. An estimated 100,000 sheep died throughout the South-West at the time.

P. G. Buckman - at the time Department of Agriculture District Veterinary Officer, Narrogin - surveyed 17 properties in the area. He found that losses in unshedded sheep 0 to 40 days off-shears ranged from 0 to 84 per cent of sheep on the property with an overall average of 27.9 per cent. Rainfall in …

Dispelling Some Myths About 'Dermo', J R. Edwards

Journal of the Department of Agriculture, Western Australia, Series 4

There are a lot of misconceptions and myths about dermatophilosis, a disease which can kill young lambs, affect wool quality, make shearing difficult and make sheep susceptible to fly strike.

One misconception is perpetuated by the incorrect use of the name mycotic dermatitis, which implies that a fungus causes the disease. This is not so.

The disease is caused by the bacteria Dermatophilus congolensis, which attacks the sheep's skin and eventually forms a lesion or scab in the wool, and so is better called dermatophilosis, 'dermo' or 'lumpy wool'.

Veterinary Epidemiologist at the Albany Regional Office, J.R. Edwards, discusses …

New Developments In Footrot Control, R B. Richards, L. J. Depiazzi, R. V. R. Gwynn

Journal of the Department of Agriculture, Western Australia, Series 4

The eradication policy for footrot in sheep adopted by the Western Australian Department of Agriculture has produced an overall decline in the number of properties with the disease.

Our knowledge of the disease has improved substantially as a result of the research conducted at the Slabany Regional Veterinary Laboratory in recent years. Laboratory tests now sssist stock inspectors and veterinary officers to distinguish between different forms of footrot and to quarantine and eradicate accordingly.

The recent discovery of more effective foot-bathing solutions by officers of the Victorian Department of Agriculture will greatly assist further eradication procedures.

Western Australia's sheep industry …

Sexuality, Privacy And The New Biology, George P. Smith Ii, Roberto Iraola

Scholarly Articles

This Article investigates two alternative methods of human conception: Specifically, the artificial insemination of unmarried women for either their own personal purposes of pregnancy without the benefit of marriage or as surrogates for infertile women. Surrogation is evaluated, then, as an analytic complement to the sexual privacy of women who are expressing their sexual freedom through unconventional means to become pregnant.

The conclusion drawn is that an unmarried woman’s fundamental right to privacy or procreation does not encompass a right to either artificial insemination or surrogation. To allow unfettered access to these two methods of conception would - quite simply …

The Insulin-Like Activity Of Human Serum, Melvin E. Klegerman

Dissertations

No abstract provided.

Detection Of Morphine And Its Analogues Using Enzymatic Hydrolysis, Joan Combie, Jerry W. Blake, Thomas E. Nugent, Thomas Tobin

Veterinary Science Faculty Patents

The invention relates to a method for hydrolyzing drug glucuronic acid conjugates present in mammalian body fluids, the conjugates being derived from a narcotic analgesic, antagonist, or agonist-antagonist whose metabolism includes conjugation with glucuronic acid. The method comprises incubating the body fluid sample at from about 60 to about 70° C., for at least about 1 hour, with 3-glucuronidase derived from Patella vulgata, and substantially increases the sensitivity of chromatographic techniques for the detection of morphine and its analogues.

Improving The Effectiveness Of Floodplain Management In Western State High-Risk Areas: Alluvial Fans, Mudflows, Mud Floods, Association Of State Floodplain Managers, United States. Federal Emergency Management Agency, California. Department Of Water Resources

FMHI Publications

No abstract provided.

Pleiochaeta Soil Survey, M Sweetingham

Experimental Summaries - Plant Research

1. Pleiochaeta soil survey - Moora District, March 1984. 2. Lupin root rot trials - 84A40, 84BA26, 84GE50, 84GE56, 84MO82, 85NO59, 84WH28. 3. Fungicides for Rhizoctonia patch control - 84E25, 84E28. 4. 83WH29 : Effect of rotation on wheat diseases. 5. Root disease in long term wheat-lupin rotation trials - 68E5, 79GE37, 80TS2, 81LG29, 82M26.

Foliar Disease Of Wheat, A. G. P. Brown

Experimental Summaries - Plant Research

Wheat leaf diseases were at much reduced levels in 1984. This may have been caused by prolonged summer rain prematurely setting off dispersal of spores and also initiating microbiological breakdown of stubble residues. No survey was carried out in 1984 but a good indication of the seasonal effect can be gained by noting that in the spray-timing experiment at Badgingarra disease levels were extremely low until the end of August some 90 days after sowing. Timing of fungicide for Septoria and Yellow Spot control. 84BA32, 84GE59. Effect of Yellow-spot at Merredin (with S. Trevenen) 84ME57. Yellow-spot is common though not …

Control Of Black Spot; Peas, Potatoes, Lettuce, Eleanor M. Carter

Experimental Summaries - Plant Research

Please find attached summaries for all experiments completed as at February 1, 1985. Crop Trial number Title Status Peas - 84MT49 Control of black spot Completed. Potatoes - 84PE25 Varietal susceptibility - Powdery scab Completed 84MD46 Varietal susceptibility to soft rot Erwinia Completed 84PE31 Yield loss and disease damage of potatoes due to Erwinia species Aborted 84MD37, 84PE32, 84PE33: Incidence of soft rot Erwinia in potato/cauliflower rotations Completed 84MN31 Yield loss and disease damage of potatoes due to Erwinia species Continuing 84MN32 Varietal susceptibility to soft rot Erwinia Continuing 84MN33 Incidence of soft rot Erwinia in potato crops Continuing Lettuce …

Take-All Of Cereals. Rhizoctonia Patch Of Cereals, G C. Macnish

Experimental Summaries - Plant Research

Part 1. A. Take all of cereals: Effect of nitrogen sources on take-all. 76LG25 (N = 50kg/ha) 82NE34. 77E4 (N = 25kg/ha). 77MT19 (N = 45 kg/ha). B. RHIZOCTONIA PATCH OF CEREALS: Rhizoctonia patch on lupins - 82E17. Abbreviations used: D - Drilled with seed G.S. - Growth stage based on H. Fisher scale NA - Not available N – Nitrogen P - Phosphorus TA - Take-all TD - Topdressed D.D. - Direct drilled T.D.D. - Triple disc drill As - Ammonium sulphate An - Ammonium nitrate (Agran 34) Sn - Sodium nitrate Ag1 - Agras No. 1 Ag2 - …

Oncolog, Volume 29, Number 03, July-September 1984, Jesus E. Medina Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Clinician Relates Thickness of Stage I Melanoma to Prognosis and Treatment
• Researcher Associates High Potassium, Low Sodium Intake with Decreased Cancer Rates
• Gene Probes Used in Leukemia Diagnosis
• MOPP Chemotherapy Proves Effective for Infants and Children with Brain Tumors

Oncolog, Volume 29, Number 01, January-March 1984, Isaiah J. Fidler Dvm, Phd, Donna R. Copeland Phd, Jack M. Fletcher Phd, Betty Pfefferbaum-Levine Md, Norman Jaffe Md, Hubert L. Ried Md, Moshe H. Maor Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Researcher Describes Early Success with Macrophages in Treating Metastasis
• Home Hyperalimentation Promotes Self-Care
• CNS Irradiation of Children Found to Impair Arithmetic-Related Abilities

A Validation Study Of The Screening Test For Developmental Apraxia Of Speech, Deborah L. Thorsen

Dissertations and Theses

The term "developmental apraxia of speech" (DAS) has been a confusing one since Morley, Court and Miller (1954) first applied it to articulatory patterns of a specific group of children. Until recently, the differentiation of diagnostic features of DAS in children as compared to other articulatory disorders has been difficult. One evaluation tool, developed by Blakeley (1980), to assist in differential diagnosis of DAS is the Screening Test for Developmental Apraxia of Speech (STDAS). This study examined the validity of this tool by comparing its results with the evaluations by three Speech-Language Pathologists knowledgeable in the area of developmental and/or …

Survey Of Language Acquisition Techniques Provided By Parents Of Talented And Gifted Children, Sharon Engen

Dissertations and Theses

Most of the studies on language acquisition techniques provided by parents have been addressed to the training of parents for prevention of language disabilities and disorders (Latzke, 1975). Few investigations have involved language acquisition of the superior functioning child (Patterson, 1981). Hence, the purpose of this study was to survey language acquisition techniques provided by parents of talented and gifted children (TAG) who were enrolled in the Beaverton School District Number 48 TAG program. The first question dealt with what materials and/or equipment did the parents use in aiding their child's language development. The second question dealt with which particular …

The Psychological Intervention Of Group Therapy For Women Coping With Genital Herpes, Susan D. Ferguson

Dissertations and Theses

Three groups of women who had been diagnosed as having genital herpes completed a series of psychological assessments over the course of the four-month research period. One group received two-hour weekly group psychotherapy sessions for eight consecutive weeks as a mode of treatment intervention. Two control groups were used for efficacy of treatment comparison. One control group consisted of regular members of a local self-help chapter for herpes victims. The second control group was formed from those volunteers willing to participate, but who did not choose, or desire, any form of treatment, Outcome measures reflected a greater improvement in psychological …

Normative Data For The Tennessee Test Of Rhythm And Intonation Patterns (T-Trip), Ray Drommond

Dissertations and Theses

Prosody is the flow of speech created by controlling elements such as pitch, rate, loudness, and stress (Tiffany and Carrell, 1977). Prosody is vital to intelligibility of speech and also communicates meaning. Despite the importance of prosody, however, few tests for the adequacy of prosodic ability in young children have been published (Koike and Asp, 1981a). To remedy this paucity of tools, Koike and Asp published the Tennessee Test of Rhythm and Intonation Patterns (T-TRIP). The clinical usefulness of the T-TRIP has been limited by a lack of normative data against which to compare individual children's performance.

The purpose of …

Process Of Goal Fulfillment: Mothers Of Children With Sleep Problems., Diana Patterson Smith

All ETDs from UAB

No abstract provided.

University Of Texas At Tyler Catalog, 1984-1986, University Of Texas At Tyler

Catalogs

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The Use Of Academic Performance As A Predictor Of Success Of The National Council Licensing Examination, Patricia O. Dardis

Electronic Theses and Dissertations

The purpose of this study was to determine the relationship between a baccalaureate nursing student's academic performance and scores received on the National Licensing Examination for Registered Nurses (NCLEX-RN); and to develop an equation to predict NCLEX-RN scores.
The sample consisted of 25 generic students who graduated in 1982 and 1983 from a small private baccalaureate liberal arts college located in the Midwest. An Ex Post Facto research design, using twenty independent variables that relate to academic performance (ACT, CPA, and NLN scores), and one dependent variable (NCLEX-RN), was utilized. Statistical analysis using Pearson's - r and Multiple Regression Analysis …

Cenobium 1984, Louisiana State University And Agricultural And Mechanical College, School Of Veterinary Medicine, Marilyn Moore

Cenobium Yearbook

Cenobium began publication in 1977 and continued through 1990. Produced by students, the yearbooks are a chronicle of the daily life and the special events experienced by veterinary students at the LSU School of Veterinary Medicine.

Observations On Relationships Between Limb Measurements And Mode Of Locomotion In Malaysian Turtles, Duayne Nyckel

Masters Theses

Twelve Genera (spanning three Families) of Malaysian Turtles were studied to determine whether bone lengths could be correlated to mode of locomotion. Ulna, humerus, tibia, femur, coracoid (among others) were measured and results were presented graphically. Five of the genera were observed singly in a large aquarium. Data were recorded on the amount of time each spent in different locomotor modes. Both limb length data and aquarium observations suggest that turtles can be grouped into three main locomotor habits (i.e. terrestrial walking, bottomwalking, and swimming). The terrestrial group includes the genera, Geochelone, Kinixys, and Gopherus. Bottomwalkers include …

Local Norms Of Personality Assessment For Rosebud Sioux, Richard H. Dana, Rodger Hornby, Tom Hoffmann

Regional Research Institute for Human Services

Measures of life stress, locus of control, world view, and values were administered to 91 Rosebud Sioux. The results provide some limited norms for local use of these measures and descriptive data for this tribe. These measures provide examples of culturally relevant, non-discriminatory instruments for assessment of Native Americans

Mental Hospital Drugging - Atomistic And Structural Remedies, Sheldon Gelman

Law Faculty Articles and Essays

Thirty years have passed since the discovery of Thorazine, a neuroleptic drug, and the drugging of American state mental patients has become commonplace. Part I distinguishes between two approaches to remedy--"structural" and "atomistic"--and, as a basis for testing the two, describes a state hospital's handling of the most serious drug side effect. This account also provides a sense of the dimensions of the drugging problems in state hospitals. Part II explores a family of atomistic remedies. These would address drugging problems by seeking to ensure that state doctors are knowledgeable about drugs and/or reasonably careful in administering them. I reject …