Decitabine-Cedazuridine In Patients With Mds And Tp53 Mutations, Samuel Urrutia, Koji Sasaki, Alex Bataller, Hagop Kantarjian, Guillermo Montalban-Bravo, James Mccloskey, Elizabeth A Griffiths, Karen Yee, Amer Zeidan, Michael Savona, Aram Oganesian, Yuri Sano, Harold N Keer, Guillermo Garcia-Manero

Faculty, Staff and Student Publications

No abstract provided.

Trends In County-Level Childhood Vaccination Exemptions In The Us, Mustafa Fattah, Lauren A Stoffel, Kate M Bubar, Samantha J Bents, Yvonne Maldonado, Peter J Hotez, Mathew V Kiang, Nathan C Lo

Faculty, Staff and Students Publications

This study examines US county-level trends in nonmedical and medical exemptions to childhood vaccination requirements.

Outcomes Following Matched Sibling Donor Transplantation For Severe Combined Immunodeficiency: A Report From The Pidtc, Ahmad Rayes, Jeffrey J Bednarski, Et Al.

2020-Current year OA Pubs

The Primary Immune Deficiency Treatment Consortium performed a retrospective analysis of 133 patients with severe combined immunodeficiency (SCID) receiving matched sibling donor (MSD) hematopoietic cell transplantation (HCT) between 1980 and 2023 at 30 North American institutions. In this largest cohort of MSD outcomes in patients with SCID to date, we examined the impact of conditioning regimen and graft-versus-host disease (GVHD) prophylaxis on survival and immune recovery. Outcomes after MSD HCT for SCID were excellent. Patients without an active infection or failure to thrive (FTT) at the time of HCT had 5-year overall survival superior to those with infection or FTT. …

Smoldering Multiple Myeloma In The United States: A Population-Based Analysis, Shi-Yi Wang, Rong Wang, Martin Schoen, John H Huber, Eric J Feuer, Jennifer Ruhl, Natalia Neparidze, Xiaomei Ma, Amy J Davidoff, Su-Hsin Chang

2020-Current year OA Pubs

No abstract provided.

Decitabine-Cedazuridine In Patients With Mds And Tp53 Mutations, Samuel Urrutia, Koji Sasaki, Alex Bataller, Hagop Kantarjian, Guillermo Montalban-Bravo, James Mccloskey, Elizabeth A Griffiths, Karen Yee, Amer Zeidan, Michael Savona, Aram Oganesian, Yuri Sano, Harold N Keer, Guillermo Garcia-Manero

2020-Current year OA Pubs

No abstract provided.

Data Management Plans For Grant Proposals, Rubab Shahzad

Day Family Research Lab Workshop Series

Fundamentals of research data management and how to create effective Data Management Plans (DMPs) and Data Management Sharing Plans (DMSP)

Immune-Mediated Necrotizing Myopathy In Association With Statin Exposure, Charlie E. Babcock, Phebie Rossi, Jennifer Hasvold

Aesculapius Journal (Health Sciences & Medicine)

Statins are first-line therapy for hyperlipidemia and are widely prescribed in primary care. Although generally safe, they carry rare but serious risks that must be considered on an individual basis. One such complication is immune-mediated necrotizing myopathy (IMNM), an autoimmune condition characterized by persistent muscle weakness and elevated creatine kinase (CK) despite discontinuation of the statin. We describe an 87-year-old man with a history of atorvastatin intolerance who was reinitiated on the medication five years later. Shortly thereafter, he developed progressive weakness, recurrent hospitalizations, and ultimately was diagnosed with IMNM confirmed by biopsy and HMG-CoA reductase antibodies. Despite treatment with …

Utility Of The Wasi–Ii 2-Subtest Full Scale Iq For Identifying Impaired Cognitive Functions, Joseph J. Ryan, David S. Kreiner, Samuel T. Gontkovsky

Archives of Assessment Psychology

This study focused on how accurately the WASI–II 2FSIQ predicts the 4FSIQ. If two subtests can identify intellectual disability, a low score might prompt a switch to the WAIS–IV or WISC–V prior to completing the four WASI–II subtests. Participants were 94 individuals with psychiatric or neurological disorders (age M = 49.04 yrs, education M = 13.48 yrs) seem for clinical evaluation. The correlation between the 2FSIQs and 4FSIQs in the total sample was high, r(92) = .96, p < .001, but the former cannot be relied upon to predict 4FSIQs. It overestimated 4FSIQs in 69.1% of the cases, with only 50% of the 2FSIQs falling within + 3 points of the 4FSIQs. However, classification accuracy statistics indicated that the 2FSIQ effectively screened for the presence of intellectual disability. A 2FSIQ standard score cutoff of ≤ 79 yielded a high probability that the 4FSIQ was also at or below the cut score.

Potential Mediators In The Relationship Between Racial Identity And Neuropsychological Performance In A Retired Nfl Cohort, Claire Stafford, Charles Golden, Ryan Bennett

Archives of Assessment Psychology

Historically, Black Americans have consistently performed more poorly than White Americans on various neuropsychological tests, with debates surrounding the causes of these differences ranging from genetic to societal factors. These differences have been documented across various cognitive domains, including memory, attention, executive function, and processing speed. Findings from previous research suggest that individuals with higher levels of education and stable marital relationships tend to exhibit better cognitive functioning, while certain football positions are linked to differences in cognitive abilities. However, the specific effects of these factors on neuropsychological performance require further investigation. The present archival study was derived from a …

Syllabus Design And Clinical Competency: A Review Of Dysphagia Training Graduate Speech-Language Pathology Programs Across North Carolina, R. Jordan Hazelwood, Kasey M. Clift, Paige H. Bradford

Appalachian Student Healthcare Research Review

Background

Despite the critical role of dysphagia management in speech-language pathology education, limited research has examined how graduate-level curriculum design and learning experiences influence clinical preparedness and competency development. The purpose of this study is to examine the relationships between instructor characteristics, syllabus design features, and the inclusion of dysphagia management competencies in graduate speech-language pathology (SLP) dysphagia course syllabi across North Carolina (NC).

Method

Instructor information and dysphagia syllabi from all accredited graduate SLP programs across NC were collected and rated. The New Dale-Chall Readability Calculator was used to evaluate syllabus readability and content complexity. The Four Dimensions of …

Phytic Acid (Insp6) Activates Hdac3 Epigenetic Axis To Maintain Intestinal Barrier Function, Sujan Chatterjee, Zachery Sin, Nguyen Tran, Loretta Vierra, Anuj Shukla, Tam Tran, George Koshkaryan, Kevin Ritter, Xue Bessie Sue, Saharat Jolak Ragsac, Seungman Park, Qian Liu, Richard Van, Katherine Huang, Kayci Huff-Hardy, Richard Rood, Anas Gremida, Martin Gregory, Chien-Huan Chen, Mira V. Han, Parakkal Deepak, Adikfi Saiardi, Henning J. Jensen, Prasun Guha

Life Sciences Faculty Research

HDAC inhibition shows promise in cancer treatment but pan-HDAC inhibitors cause gastrointestinal issues in 48% of patients. Understanding HDAC activation mechanisms is crucial to treating diverse diseases beyond cancer. Our study reveals that inositol polyphosphate multikinase (IPMK) and inositol hexakisphosphate (InsP6 or phytic acid), enriched in vegan diets, play essential roles in activating the HDAC3 epigenetic axis and maintaining intestinal barrier integrity. IPMK binds to HDAC3 and drives InsP6 synthesis, which selectively activates HDAC3 at a 10 nM concentration by recruiting the DAD domain of its corepressor protein. IPMK deletion diminishes HDAC3 activation, leading to histone hyperacetylation and MMP gene …

The Wear-Bot Checklist: A Risk Of Bias Tool For Evaluating Validity And Reliability Research In Wearable Technology, Bryson Carrier, Jennifer A. Bunn, Chris Eschbach, Joel D. Reece, Gregory J. Welk, Brett A. Dolezal, James W. Navalta

Kinesiology and Nutrition Sciences Faculty Research

This paper proposes an innovative tool designed to standardize the evaluation of validity and reliability studies in the rapidly evolving field of wearable technology. We introduce the WEArable Technology Risk of Bias and Objectivity Tool (WEAR-BOT), a tool that addresses the need for a comprehensive and systematic way to assess bias in studies examining consumer-grade and research-grade wearable devices. This is the first tool designed to evaluate the risk of bias in validation and reliability studies. Other risk of bias tools like the Cochrane ROB, COSMIN, or the many other risk of bias tools are designed for different study methodologies …

Abortions In The Mountain West, 2022-2025, Olivia K. Cheche, Caitlin J. Saladino, William E. Brown Jr.

Health

This fact sheet presents data on the number of abortions provided annually in the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah between July 2022 and June 2025. The data are retrieved from the Society of Family Planning’s #WeCount report,  which includes data on abortion volume across all 50 U.S. states and Washington, D.C. This fact sheet focuses on the administration of both in-person and telehealth abortions in the Mountain West.

Tumor Necrosis Factor Alpha Inhibition Improves Fetal Growth In A Rat Model Of Preeclampsia, Laura E. Coats, Nathan Campbell, Dylan Solise, Gabrielle M. Chamoun, Adam Z. Rawls, Alexandra Demesa, Ty Turner, Baoying Zheng, Barbara T. Alexander, Babbette Lamarca

Physiology & Biophysics

Introduction

Oral Health Related Quality Of Life In A Group Of Egyptian Preschool Children With Early Childhood Caries: A Cross-Sectional Study, Sara Adel Botros, Sara Magdy, Asmaa Abou Bakr, Ola Abdel Geleel

Dentistry

No abstract provided.

Staff Education To Enhance Self-Care Support For Nurses, Charisma Olive

Walden Dissertations and Doctoral Studies

Background: High stress and burnout among maternity unit nurses negatively impact both nurse well-being and patient care quality. Research indicates that nurse burnout is associated with impaired cognitive function, reduced emotional connection with patients, and suboptimal job performance, all of which directly impact patient safety. Purpose: The purpose of this quality improvement project was to implement a comprehensive staff education program teaching evidence-based self-care strategies while assessing organizational support systems for nurse wellness. Methods: This three-phase quality improvement project utilized Lewin’s change management model combined with the ADDIE instructional design framework. Phase I (baseline assessment) involved 17 participating maternity nurses …

The Racial Politics Of Early Dentistry And The Terrible “Toothache Blues”, Bronwen Mcveigh Phd

Journal of the American College of Dentists

In interwar America, the relatively young profession of dentistry was developing rapidly. As the government, health institutions, and social organizers focused more intently on notions of national wellness, questions about how to achieve a healthy smile—and what a healthy smile should look like—proliferated. Groups like the National Dental Association worked to establish rigorous standards of technique, define ethical behavior, and encourage dentists to develop business acumen, yet the surprising proliferation of blues songs about dubious dentists tricking unassuming clients, or about fraught love affairs allegorized by disastrous dental exams, highlights the equivocal nature of many developments in early dentistry.

This …

Integrating Zotero With Your Writing: From Research To Publication – Hslic Workshop Feb 2026, Evelyn Wang

HSLIC Faculty and Staff Instructional Resources

This HSLIC workshop presentation provides a practical, step‑by‑step guide to integrating Zotero into the research and writing workflow. Topics include installing and configuring Zotero and the Zotero Connector, collecting references from databases and web pages, organizing items with collections, subcollections, tags, and PDF attachments, inserting citations and generating bibliographies in Microsoft Word and Google Docs, managing and annotating PDFs, handling title case versus sentence case, detecting and merging duplicate records, and using advanced features such as Zotero sync, group libraries, collaboration tools, custom citation styles, and ZoteroBib.

The Dental Phantom As A Tool For Exploring Fear, The Face, And Dental Education, Christine Slobogin Phd

Journal of the American College of Dentists

Dental phantoms have been used in dental education since the late nineteenth century. These pedagogical objects – particularly those from the first half of the twentieth century – have today enjoyed a resurgence of interest in the art and film worlds. After first outlining the history and pedagogical purposes of the dental phantom, this article examines what the artistic and filmic attractions to the aesthetics of these objects can tell us about fear, the mouth and the face, and dental education. How and why can a dental teaching tool be scary? Arriving at some answers to this question – reached …

A Dental Clinical Humanities Program At Uthealth Houston School Of Dentistry: The First Ten Years And Future Directions, Angela P. Gomez Edd, Mba, Ms, Deborah R. Franklin Dds, Lpc, Ctts, Nathan Carlin Phd, Joelle Robertson-Preidler Phd, Hec-C

Journal of the American College of Dentists

The Dental Clinical Humanities Certificate Program was implemented 10 years ago at the UTHealth Houston School of Dentistry to expose dental students to dental humanities content and engage them in educational experiences exploring oral health care through humanities lenses, providing insight into the human condition and patient-centered approaches. With more than 30 students having graduated from the program, we conducted a retrospective analysis of the exit surveys previously distributed at the end of each academic year. The exit survey focused on their general program feedback, including the effects of dental humanities as an academic enterprise, cultivating their self-knowledge and serving …

The Pent-Up Demand For Humanities And Ethics In Dentistry, Nathan Carlin, Nanette Elster, Catherine Flaitz, Nicholas Mercado Drph, Ms, Laurie Munro, Chelsey Patten, Joelle Robertson-Preidler, Margie Hodges Shaw Jd, Ma, Phd, Christine Slobogin Phd, Matthew Wynia, Michael Yunker Dds

Journal of the American College of Dentists

The Editorial is a feature in each issue of the JACD. It includes commentary on issue content, relevant topics, or other items of interest to the fellowship.

The Vipeholm Experiments: A Case Study Of Unethical Dental Research, Lainie Ross Md, Phd

Journal of the American College of Dentists

Modern-day research ethics training often begins with a discussion of the medical research atrocities committed by Nazi health care professionals and the resulting 10-principle Nuremberg Code, which is often considered to be the beginning of modern-day medical research regulations. It is occasionally mentioned that Nazi dentists also conducted unethical research in the concentration camps, and a few were brought to trial. In this manuscript, I compare two studies (one medical and one dental) conducted after World War II that violated the Nuremberg Code.

I describe and compare the well-known Willowbrook Hepatitis studies conducted by infectious disease doctors on vulnerable institutionalized …

Information Distortion As A Source Of Overconfidence In Managerial Decisions, Peter Boyle, Pete Nye

All Faculty Scholarship for the College of the Sciences

Managers confronting important strategic decisions often receive diagnostic information sequentially over time. As new information becomes available, they may need to update their understanding of the situation and possibly revise their preferences. During a decision, as a preference develops for one alternative course of action, a nonconscious goal of maintaining consistency between that preference, however tentative, and the new information can lead to an interpretation of that information so as to support the current preference. This tendency to bias or distort information to support the currently preferred option can in turn lead to even greater confidence in that leading option, …

The Mouth As A Mirror: A Parent- Hygienist’S Ethical Reflections On Oral Healthcare And Pompe Disease, Anika Atkins Ma, Rdh

Journal of the American College of Dentists

This reflective narrative explores the ethical tensions and emotional realities of a dental hygienist who is also the parent of a child with Pompe disease. Drawing from personal experience and care ethics philosophy, the author examines how traditional clinical frameworks—centered on autonomy, beneficence, and protocol— often fall short when addressing the needs of medically fragile children. The piece weaves in the work of care ethicists and pastoral ministry to embrace the philosophy of caregiving as presence, to suggest that oral healthcare must evolve to include responsiveness, context, and relationship-based decision-making. Through the dual lens of provider and parent, the narrative …

Restoring Trust: A Fair Chance At A Bright Smile And The Human Side Of School-Based Dentistry, Rubin Sorrell Ii, Mph, Dds

Journal of the American College of Dentists

The Fair Chance at a Bright Smile (FCAABS) program represents a humanistic, community- centered approach to dentistry that redefines access, education, and dignity in oral health. Developed and refined through a year-long pilot partnership with the San Francisco Unified School District, FCAABS integrates preventive dental care, oral health education, and career exposure for students from pre-kindergarten through high school. This manuscript argues that beyond clinical outcomes, FCAABS reveals a deeper truth: oral health is intrinsically social, emotional, and moral. It examines the program through the lens of the humanities and ethics, exploring how narrative, empathy, and cultural context inform both …

Hydroxypropyl Methylcellulose As A Mucoadhesive Polymer In Ethanol-Free Buprenorphine Gel For Neonatal Sublingual Delivery, Sanskruti Dave, Viren Soni, Samarth A. Shah, Walter K. Kraft, Gagan Kaushal

College of Pharmacy Faculty Papers

Buprenorphine (BUP) is widely used in the treatment of neonatal opioid withdrawal syndrome (NOWS). However, the most compounded formulation contains 30% ethanol, despite regulatory and clinical concerns regarding ethanol exposure in pediatric patients. Thus, this research aimed to develop an ethanol-free sublingual (SL) gel formulation of BUP that would be safe, stable, and suitable for NOWS. Multiple polymers were screened as gelling agents, with hydroxypropyl methylcellulose (HPMC) emerging as the ideal base polymer for the formulation due to its optimal pH, rheological characteristics, and stability. The formulated gels were stored at room temperature and refrigerated conditions for 30 days and …

Development Of A Comfort Care Clinical Practice Guideline And Standardized Comfort Care Kits In Adult Home Hospice, Kelly Miller

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project focused on the development and expert appraisal of a clinical practice guideline (CPG) to improve home-based comfort care in hospice settings. Terminally ill patients frequently experience distressing symptoms such as pain, dyspnea, and nausea, yet inconsistent symptom management and documentation practices persist across hospice care (Henson et al., 2020). A CPG was developed to evaluate a comfort care kit for patients. The CPG was independently reviewed by a three-member expert panel using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument, which consists of 23 items that are organized into …

Developing A Comprehensive Program Plan For Postpartum Mental Health Assessment And Follow-Up Care, Kimberly Osborne

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice project was an executive leadership proposal to develop an evidence-based program plan for standardized postpartum mental health screening and structured referral processes within an obstetric clinic. The practice problem was inconsistent postpartum mental health screening and follow up. Internal organizational data demonstrated elevated no-show and cancellation rates among obstetric patients referred for mental health services, reflecting gaps in care coordination, particularly for rural and underserved populations. The purpose of this project was to develop a comprehensive program plan guided by the following practice-focused question: Will a standardized postpartum mental health screening and structured referral program …

Staff Education Of Fall Prevention Intervention In The Emergency Department, Jonathan Jaramillo

Walden Dissertations and Doctoral Studies

Patient falls remain a significant patient safety concern in emergency departments (EDs) despite the routine use of fall risk screening tools. At the project site, continued fall events suggested a gap in staff knowledge, confidence, and consistent application of evidence-based fall prevention strategies. This Doctor of Nursing Practice (DNP) quality improvement project evaluated whether a targeted staff education intervention would improve ED nursing staff's knowledge, confidence, and intent to identify fall risk, implement prevention strategies, and respond appropriately to patient falls. Guided by the Analyze, Design, Develop, Implement, and Evaluate (ADDIE) instructional design model, an evidence-based educational intervention was developed …

Development Of An Evidence-Based Educational Intervention Designed To Increase Staff Knowledge And Competence In Comprehensive Fall-Prevention Practices, Jacqueline U. Becerra

Walden Dissertations and Doctoral Studies

Inpatient falls continue to represent a significant nurse-sensitive quality indicator associated with patient injury, extended hospital stays, and increased healthcare costs. Despite the presence of established fall-prevention protocols, inconsistent completion of fall-risk assessments and uneven application of prevention strategies contributed to ongoing fall events at the project site. The practice problem addressed in this Doctor of Nursing Practice (DNP) project was the lack of consistent staff knowledge and application of evidence-based fall-prevention practices. The purpose of this evidence-based quality improvement project was to implement and evaluate a structured fall-prevention staff education program to increase inpatient staff knowledge related to fall-prevention …