Digital Commons Network^™

Responding To American Indian Communities: Southwest American Indian Collaborative Network (Saicn) Cancer Educational Activities, Naomi A. Lane, Kathleen Evans, Agnes Attakai, Catherine Witte, Maylynn Riding In-Warne, Kathryn Coe

Journal of Health Disparities Research and Practice

Developing educational materials and providing trainings in American Indian communities is a highly rewarding activity. However, to do so successfully a number of complex issues must be faced and cultural-tailored strategies to promote awareness must be developed based on the unique traditions of each tribe. In this paper we describe the educational activities conducted over a four year period by the Southwest American Indian Collaborative Network, a project funded by the National Cancer Institute’s Center to Reduce Cancer Health Disparities. Activities fell into two broad areas: dissemination of cancer information through trainings and workshops and development of culturally-tailored educational materials.

Alternative Approaches For Medical Countermeasures To Biological And Chemical Terrorism And Warfare, Thomas Hartung, Joanne Zurlo

Biomedical Research and Alternative Methods Collection

The desire to develop and evaluate drugs as potential countermeasures for biological and chemical threats requires test systems that can also substitute for the clinical trials normally crucial for drug development. Animal models have limited predictivity for drug efficacy, as is well known from many disappointments in clinical trials. Traditional in vitro and in silico approaches are not really game changers here, but the substantial investment into novel tools now underway might bring about a second generation of alternative approaches. The avenue pursued focuses primarily on the development of a Human on a Chip, i.e., the combination of different three-dimensional …

Knowledge, Wisdom, And Service: The Meaning And Teaching Of Professionalism In Medicine, Matthew K. Wynia

Center for the Study of Ethics in Society Papers

Papers presented for the Center for the Study of Ethics in Society Western Michigan University. Presented September 29, 2011.

Challenges Of Being A Black Student Athlete On U.S. College Campuses, Wycliffe W. Njororai Simiyu

Health & Kinesiology Faculty Publications and Presentations

The purpose of this Literature review article is to examine the social, cultural, individual and institutional racist factors that pose challenges to many African American college athletes, both men and women, to develop skills outside sports that are necessary to succeed in college and life. The passion for athletics by Black youth has to be positioned within the wider racist environment that one is exposed to while growing up. The dominant presence of Blacks in the high profile sports of football, basketball and track and field while having lower graduation rates compared to White athletes deserves scholarly interrogation. This article …

The Rise And Fall Of The Doctor-Patient Relationship, Thoams R. Cole

Houston History of Medicine Lectures (2006-2012)

This talk will outline the history of the doctor-patient relationship in the West. It will touch briefly on medicine in Greek and Roman antiquity, using key texts from Hippocrates and Galen. It will also sketch the changing balance of the religious and the secular in medieval medicine. Finally, it will outline the rise of the modern personal doctor-patient relationship in the 18th century and analyze the chronic dissatisfaction that settled over relations between doctors and patients in the last quarter of the 20th century.

A First-Generation Multi-Functional Cytokine For Simultaneous Optical Tracking And Tumor Therapy, Shawn Hingtgen, Randa Kasmieh, Elizabeth Elbayly, Irina Nesterenko, Jose-Luiz Figueiredo, Rupesh Dash, Devanand Sarkar, David Hall, Dima Kozakov, Sandor Vajda, Paul B. Fisher, Khalid Shah

Human and Molecular Genetics Publications

Creating new molecules that simultaneously enhance tumor cell killing and permit diagnostic tracking is vital to overcoming the limitations rendering current therapeutic regimens for terminal cancers ineffective. Accordingly, we investigated the efficacy of an innovative new multi-functional targeted anti-cancer molecule, SM7L, using models of the lethal brain tumor Glioblastoma multiforme (GBM). Designed using predictive computer modeling, SM7L incorporates the therapeutic activity of the promising anti-tumor cytokine MDA-7/IL-24, an enhanced secretory domain, and diagnostic domain for non-invasive tracking. In vitro assays revealed the diagnostic domain of SM7L produced robust photon emission, while the therapeutic domain showed marked anti-tumor efficacy and significant …

Cognitive Effects Of One Season Of Head Impacts In A Cohort Of Collegiate Contact Sport Athletes, Thomas W. Mcallister,, Laura A. Flashman, Arthur C. Maerlender, Richard M. Greenwald, Jonathan G. Beckwith, Tor D. Tosteson, Joe Crisco, Per Gunner Brolinson, Stefan Duma, Ann-Christine Duhaime, M. R. Grove, John H. Turco

Center for Brain, Biology, and Behavior: Faculty Publications

Objective: To determine whether exposure to repetitive head impacts over a single season negatively affects cognitive performance in collegiate contact sport athletes.

Methods: This is a prospective cohort study at 3 Division I National Collegiate Athletic Association athletic programs. Participants were 214 Division I college varsity football and ice hockey players who wore instrumented helmets that recorded the acceleration-time history of the head following impact, and 45 noncontact sport athletes. All athletes were assessed prior to and shortly after the season with a cognitive screening battery (ImPACT) and a subgroup of athletes also were assessed with 7 measures from a …

Culture Ontogeny: Lifespan Development Of Religion And The Ethics Of Spiritual Counselling, Glen Milstein, Amy Manierre

Publications and Research

The counsellor has an ethical obligation to treat the whole person. Humans are cultural beings and the foundation of most cultures is religion. Religion and culture are received from our early relation~ ships and modified through later relationships across the lifespan. The paper introduces the term "culture ontogeny" to emphasize that this is a biological process wherein abstract ideas of culture and religion become material in the developing neurophysiology of each brain. A framework and methods are offered to examine the changing roles of religion in clients' emotional self~ structure, inclusive of those who describe themselves as spiritual, not religious. …

Blast-Induced Brain Injury: Influence Of Shockwave Components, Dexter V. Reneer

Theses and Dissertations--Neuroscience

Blast-induced traumatic brain injury (bTBI) has been described as the defining injury of Operations Enduring Freedom and Iraqi Freedom (OEF/OIF). Previously, most blast injury research has focused on the effects of blast on internal, gas filled organs due to their increased susceptibility. However, due to a change in enemy tactics combined with better armor and front-line medical care, bTBI has become one of the most common injuries due to blast. Though there has been a significant amount of research characterizing the brain injury produced by blast, a sound understanding of the contribution of each component of the shockwave to the …

Pre, Peri, And Post-Migration Perspectives Of Mexican National Refugees Related To Experiences Of Violence, Migration, And Resettlement Along The Texas-Mexico Border, Jana L. Mccallister

Open Access Theses & Dissertations

For the past six years, the war on drugs in Mexico has resulted in the out-migration of tens of thousands of Mexican nationals fleeing violence, many settling in El Paso, Texas. The historical context of being pulled to the U.S. for economic opportunity had changed. Mexican nationals were now refugees pushed out of their country for safety. Because the context of migration had changed, the close proximity and similarities between El Paso, Texas and Ciudad Juárez, and the availability of social support in the U.S., the experiences of this refugee cohort were unique. Because increasing numbers were seeking mental health …

Program And Proceedings: Nebraska Academy Of Sciences 1880–2012, 132nd Anniversary Year, One Hundred-Twenty-Second Annual Meeting

Nebraska Academy of Sciences: Programs and Proceedings

Program

Applied Science and Technology

Biological and Medical Sciences

Nebraska Wesleyan University Health and Sciences Graduate School Fair

Aeronautics and Space Science, Poster Session

Maiben Memorial Lecture: "The Status of Nebraska's Native Aspen," "Buffalo" Bruce McIntosh, Western Nebraska Resources Council

Aeronautics

Anthropology

Biological and Medical Sciences

Chemistry and Physics

Collegiate Academy: Biology

Collegiate Academy: Chemistry and Physics

Earth Science

History/Philosophy of Science

Junior Academy, Senior High Competition

Teaching of Science and Math

Junior Academy, Junior High Competition

Encounters With Witchcraft, Norman Miller

Dartmouth Scholarship

My first experience with witchcraft in Africa occurred in March 1960 in Mombasa, Kenya, just as I stepped off the gangway of the MS Inchanga following a voyage from India. Next to the ship in a dockside kiosk I saw a newspaper with the headline, “European Geologist Attacked in Gogoland: Witchcraft Suspected.” It was the story of a 22-year-old British geologist, William Hanning, who had been prospecting for minerals in a remote part of nearby Tanzania when by mistake he dug into a burial ground. He was believed to be a witch, disguised as a European, out to steal body …

The Yellow Flag Of Quarantine: An Analysis Of The Historical And Prospective Impacts Of Socio-Legal Controls Over Contagion, Peter Oliver Okin

USF Tampa Graduate Theses and Dissertations

Under the ancient threat of morbidity and mortality from infectious diseases, human societies have responded for thousands of years by imposing social containment measures. Even before theorists and laymen recognized the existence of pathogenic organisms, or fully understood the principles of contagion, many societies and individuals did empirically infer that such diseases were transmissible from human to human (as well as sometimes between animals and humans). Having few effective technological measures to prevent or treat contagions, they did devise a variety of socio-behavioral procedures for separating overtly ill persons or suspected disease-carriers from nominally uninfected people. These methods included various …

A Case Study For Large-Scale Human Microbiome Analysis Using Jcvi’S Metagenomics Reports (Metarep), Johannes Goll, Mathangi Thiagarajan, Sahar Abubucker, Curtis Huttenhower, Shibu Yooseph, Barbara A. Methe

Open Access Publications

No abstract provided.

The Role Of Animal-Assisted Therapy In Initial Psychotherapy Sessions With Adolescents, Erin B. Stromberg

Dissertations and Theses @ UNI

Animal-assisted therapy (AAT) is defined as "a goal directed intervention in which an animal, meeting specific criteria, is an integral part of the treatment process" (Nebbe, 1995, p. 40). Since its first introduction into the scientific community in the 1960s, AAT has grown in both recognition and application. This is primarily attributable to the characteristics of AAT that allow it to be appropriate for a wide range of populations. These qualities are shown to be especially effective in research with children (Menzies Inc., 2003). Interventions that exercise the advantageous qualities of AAT, and its service in promoting the well being …

A Bridge To One World: An Indigenous Wisdom-Based Approach To Designing A Transcultural Patient Family Advisory Council, Julie Lundberg

Theses and Graduate Projects

As health care organizations face increasing challenges to accommodate diverse patient populations amid growing concerns of persistent health disparities, there is urgent need to better understand and listen to diverse, unique patient experiences. This paper describes the design and implementation of a transcultural Patient Family Advisory Council (PFAC) as a concrete step towards ensuring that the voices of culturally diverse patients and families are effectively engaged to improve the patient experience at a large, Midwestern healthcare organization. Storytelling, ritual and dialogue provide a wisdom-based approach to the design of a Bridge to One World practice model grounded in Leininger's Culture …

Inhibition Of Cysteine Protease By Platinum (Ii) Diamine Complexes, Chaitanya Rapolu

Masters Theses & Specialist Projects

Chemotherapy is the first line of treatment used in cancer. Chemotherapy drugs such as cisplatin, carboplatin and oxaliplatin are used in treatment. Cisplatin enters the cell through copper transporter CTR1 by passive diffusion and bind to DNA and proteins. Cisplatin is found to inhibit several enzymes targeting cysteine, histidine and methionine residues, which are expected to be responsible for its anticancer activity. A better understanding of how the size and shape and leaving ligands of platinum complexes affect cysteine protease, papain enzyme are studied. This could give new ways to optimize anticancer activity. The activity of papain enzyme was measured …

The Role Of Cortisol In The Cycle Of Violence, Joshua Leigh Gowin

Dissertations and Theses (Open Access)

Child abuse and neglect are universal risk factors for delinquency, violence and aggression; this phenomenon is known as the cycle of violence. Despite a wide body of research demonstrating this phenomenon, the processes which mediate this relationship remain largely unknown. One potentially relevant result of abuse and neglect may be disruptions in the development of the body’s stress response, specifically the function of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA-axis, and its end-product, cortisol, may play a role in regulating aggressive behavior, but this function may be disrupted following abuse and neglect. Another risk factor for aggression, psychopathy, may mediate the …

Medicine Of The Future Facilitated By Dr. Michio Kaku, Multicultural Center

Multicultural Student Services Center

Dr. Michio Kaku, Henry Semat Professor, Theoretical Physics, City University of New York. During the 21st century, dramatic advances in science and technology will expand the capacity of health care to extend the human life span and improve the medical quality of life. Genomic medicine will enable physicians of the future to apply computer algorithms in organizing and analyzing genomic data to predict susceptibility to disease. Regenerative medicine will utilize stem cells to facilitate the repair, replacement, and re-growth of aging, damaged, or diseased organs, such as the heart, liver, lungs, pancreas, bladder, and ovaries, in patients suffering from cardiovascular …

Sir William Osler And The Muniments Of The Almshouse At Ewelme, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

No abstract provided.

The Historical Importance Of Transylvania University’S Medical Department (1799-1859), Focusing On The Little Known Secret Kappa Lambda Society Of Hippocrates And The Origin Of The American Medical Association's Principles Of Medical Ethics, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

No abstract provided.

Book Review: Lessons Of War, Ronald J. Koshes, Md

Jefferson Journal of Psychiatry

MILITARY PSYCHIATRY: A COMPARATIVE PERSPECTIVE

Richard A. Gabriel, editor

New York, The Greenwood Press 1986, 170 pages

Obstetrical Forceps: History, Mystery, And Morality, Ronald L. Young

Houston History of Medicine Lectures (2006-2012)

The history of obstetrical forceps has almost always been one cloaked in controversy after a long history of being shrouded in mystery. Forceps have a long history and have evolved from facilitating the delivery of dead fetuses to aiding in the delivery and survival of live babies. In the middle of all of this arises the story of the Chamberlain family whose contribution was enormous but whose behaviors pushed at the envelope of (at least) our present-day concepts of medical ethics. This lecture traces an interesting story that spans a millennium.

Mathematical Methods For Biosensor Models, Qi Wang

Doctoral

A biosensor is defined as a compact analytical device incorporating a biological sensing element integrated within a physico-chemical transducer whose aim is to produce optical or electronic signals proportional to the concentration of an analyte in a sample. Biosensors offer enormous potential to detect a wide range of analytes in health care, the food industry, environmental monitoring, security and defence. The beneficial impact on society as a result of the availability of such systems is immense, therefore investigating any strategy that could reduce development times and costs and reveal alternative designs is of utmost importance. In particular, mathematical modelling and …

Ada News - 06/20/2011, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Download The Full Pdf Of Jefferson Surgical Solutions Spring 2011, Volume 6, Number 1

Jefferson Surgical Solutions

No abstract provided.

News In Brief

Jefferson Surgical Solutions

No abstract provided.

Those Who Give: Making A Difference Now And Down The Road: The Howell Professorship In Pancreatic Cancer Research

Jefferson Surgical Solutions

No abstract provided.

Resident Update: Lieutenant Commander Daniel R. Grabo

Jefferson Surgical Solutions

No abstract provided.

Creating Second Chances For All Ages: The Live Donor Liver Transplant Program

Jefferson Surgical Solutions

No abstract provided.