Digital Commons Network^™

The Effects Of Vaping On Oral Streptococci And Oral Inflammation, Matthew Caldwell

Honors Undergraduate Theses

E-cigarette (e-cig) use is rising, but much is unknown about the effects of its vapor. This vapor contains chemicals such as propylene glycol, a known antimicrobial, and nicotine, whose derivatives are carcinogenic. Here, we study the effects of vaping on resident bacteria of the oral cavity and on oral cell inflammation. Oral streptococci are major residents in the oral cavity, with S. mutans the primary cause of dental caries. Growth and biofilm formation have been shown to be enhanced upon exposure to traditional cigarette smoke in vitro. In this study, we analyzed the effects of e-cig vapor on growth …

Killing Them To Save Us’: Lessons From Politicide For Preventing And Countering Terrorism, Clark R. Mccauley

Psychology Faculty Research and Scholarship

This chapter reviews and extends the analysis of mass political murder advanced by Chirot and McCauley, then applies this analysis to understanding and countering terrorism. The justification for this application is that both politicide and terrorism target civilians in the context of asymmetric conflict. Three generalizations emerge. Politicide and terrorism cannot be understood or countered without (i) studying both sides in the conflict, (ii) separate studies of leaders, perpetrators, and mass sympathizers, and (iii) acknowledgment of the threats and grievances perceived by both sides. The chapter concludes with implications for fighting the war of ideas against jihadist and right-wing terrorists.

Indigenous Healing In New Zealand: An Anthropological Analysis Of "Traditional" And "Modern" Approaches To Well-Being, Lillian T. Brice

Honors Theses

Drawing on contemporary anthropological approaches used by scholars of well-being and medical anthropology (i.e. Michael Jackson and Lisa Stevenson), I explore how indigenous healers in New Zealand blend “traditional” and “modern” elements to establish a creative and inclusive system. Specifically, I explore the use of herbal treatments, ritual chanting, and ceremonies that encapsulate Māori cultural values. I also explore the impact of biomedicine and New-Age wellness approaches on indigenous healing. I argue that Māori healing moves beyond the binary of “tradition” and “modern” as healers merge the past and present and combine the foreign and native. My research is based …

The Interleukin-12 Family Of Cytokines And Receptor Signaling In Graft-Versus-Host Disease, David Bastian

MUSC Theses and Dissertations

Allogeneic hematopoietic stem cell transplantation (allo-HCT) is an effective means by which to treat a wide variety of diseases resulting from dysfunctional hematopoiesis due to a potent anti-tumor response known as the graft-versus-tumor (GVT) effect after chemotherapy and/or irradiation. The necessity of donor T cells to mediate GVT is offset by the consequential development of graft-versus-host disease (GVHD); a leading cause of mortality among allo- HCT recipients. The IL-12 family of cytokines signals through Janus Kinase 2 (JAK2) and is comprised of IL-12, IL-23, IL-27, IL-35 and IL-39. IL-12 (p35+p40) and IL-23 (p19+p40) have well documented proinflammatory functions responsible for …

Sin Papeles: The Experiences Of Undocumented Central American Immigrants In The United States, Elizabeth Jarquin

Department of Family Therapy Dissertations and Applied Clinical Projects

In the United States, the topic of immigration represents a source of intense debate, which has escalated in recent years. Research indicates that Latinx immigrants are negatively impacted by current immigration policies— they are feeling afraid, angry, exhausted, defeated, overwhelmed, and concerned about themselves and their family (Castrellón, Rivarola, & López, 2017; Wray-Lake et al., 2018). This research, however, has largely neglected the Central American subgroup and the experiences of undocumented immigrants. The purpose of this study was to understand the experiences of undocumented Central American immigrants and their families within the current sociopolitical context. I utilized interpretative phenomenological analysis …

The Hsp90 Inhibitor, Auy-922, Ameliorates The Development Of Nitrogen Mustard-Induced Pulmonary Fibrosis And Lung Dysfunction In Mice, Pavel Solopov, Ruben M.L. Colunga Biancatelli, Margarita Marinova, Christiana Dimitropoulou, John D. Catravas

Bioelectrics Publications

Increased levels of heat shock protein 90 (HSP90) have been recently implicated in the pathogenesis of pulmonary fibrosis and the use of HSP90 inhibitors constitutes a potential therapeutic approach. Similarly, acute exposure to nitrogen mustard (NM) is related to the development of chronic lung injury driven by TNF-α, TGF-β, ERK and HSP90. Thus, we developed a murine model of NM-induced pulmonary fibrosis by instilling C57BI/6J mice with 0.625 mg/kg mechlorethamine hydrochloride. After 24 h, mice began receiving AUY-922, a second generation HSP90 inhibitor, at 1 mg/kg 2 times per week or 2 mg/kg 3 times per week, for either 10 …

Evidence-Based Diagnosis Of Posttraumatic Stress Disorder Using Quantitative Electroencephalography, Roger Yoder

Walden Dissertations and Doctoral Studies

Diagnosing post-traumatic stress disorder (PTSD) is challenging and is currently, diagnosis through self-administered checklists. Because a diagnosis of PTSD can open up significant benefits to compensation, education, and medical care, people can tailor their responses to the checklist to help ensure a diagnosis of PTSD. The purpose of the study was to examine the utility of the quantitative electroencephalograph for diagnosing PTSD. Frequency and presence of biomarkers and alpha brain wave symmetry in the frontal and parietal lobes were examined. Research questions involved examining the presence of alpha wave imbalance across the frontal lobe and between the right and left …

The Impact Of Anterior Cruciate Ligament Ruptures On Subchondral Bone Density In Collegiate Populations, Zach Harbaugh

Electronic Theses and Dissertations

The purpose of this study was to determine whether anterior cruciate ligament (ACL) rupture and reconstruction would lead to any significant changes in subchondral bone at the proximal tibia within 1 to 5 years post-surgical repair. Fifteen individuals (3 male, 12 female), aged 18 to 29 years old, who had sustained an ACL rupture and subsequent repair within the last 5 years were recruited for this study. An age and sexmatched control was recruited to match each participant. Subchondral volumetric bone mineral density (vBMD) of the proximal tibia was measured using peripheral quantitative computed tomography (pQCT). Additionally, jump force and …

Spatially Fractionated Radiation Therapy: History, Present And The Future, Weisi Yan, Mohammad K. Khan, Xiaodong Wu, Charles B. Simone Ii, Jiajin Fan, Eric Gressen, Xin Zhang, Charles L. Limoli, Houda Bahig, Slavisa Tubin, Waleed F. Mourad

Department of Radiation Oncology Faculty Papers

No abstract provided.

The Impact Of The Nursing Shortage On The Quality Of Care Of Veterans, Brian Alexander Fainguersch

Honors College Theses

No abstract provided.

Integrating The Natural Healing Process For Post-Traumatic Stress Disorder Treatment In Veterans Through A Healing Garden., Taiwo A. Ajibade

Graduate Theses, Dissertations, and Problem Reports (ETD)

In 2002, several ex-service personnel brought a court case against the Ministry of Defense for the inability to identify PTSD issues at an early stage and to provide support and effective treatment (Langston et al. 2007). Also in recent times, reports have suggested that US marine and army infantry units returning from duty in Iraq and Afghanistan have a higher level of expected proportions of mental disorders and that about 10% of personnel are returning home are with symptoms of post-traumatic stress disorder (Smith et al., 2008). This discovery made it pertinent to look for natural ways to assist veterans …

Bioterrorism: Exploring Factors For Improving Nurse Preparedness, Policies, And Practices, Leone Okey Tom-James

Walden Dissertations and Doctoral Studies

Ebola virus release/attack in New Jersey could go unnoticed but have immediate and long-lasting effects on the broader population and security. The risk underscores the need to prepare and enhance the state’s efforts to deal with a release and treat the confirmed cases. This descriptive single case research explored factors for improving nurses’ preparedness, policies, and practices for a bioterrorism release/attack. The epidemiological triangle conceptual framework was used descriptively in exploring, and developing a knowledge base of Ebola virus pathogenicity, characteristics, routes of transmission, and infection. The unit of analysis was Summit Ridge Genesis Healthcare Center. The theory of robust …

Family Functioning During Deployment And Reintegration Of Military Members, Heather Graham

Walden Dissertations and Doctoral Studies

Military members and their families face unique stressors related to separation and reintegration. These life-changing events can lead to domestic violence, divorce, depression, suicide, and behavioral problems within the family. It was unknown whether the implementation of a nursing clinical practice guideline (CPG) would help nurses to identify family functioning concerns or psychosocial issues enabling earlier interventions. The purpose of this doctoral project was to create a CPG that can be used at military treatment facilities (MTFs) to screen military members and their families to identify family functioning concerns so that the provider can make referrals as needed. The circumplex …

Start Of Epidemy In A City: Short-Term Forecast Of Covid-19 With Gmdh-Based Algorithms And Official Medical Statistics, Anna Boldyreva, Mikhail Alexandrov, Olexiy Koshulko, Svetland Popova

Conference papers

The sudden onset and quick development of an unknown epidemic may lead to tragic consequences: panic of population due to victims and unpreparedness of authorities for effectively help to population. These circumstances define extremely high requirements to the tools for short-term operational forecast. Namely, such tools should provide reliable results when model of phenomenon is unknown (factors of disease spreading) and data are limited (time series of observations). GMDH-based algorithms just meet these requirements unlike modern differential or advanced statistical models. In this study we test different algorithms from GMDH Shell platform on the example of Covid-19 epidemic in Moscow …

Understanding Dynamics Of Pandemics, Levent Akin, Mustafa Gökhan Gözel

Turkish Journal of Medical Sciences

Along the centuries, novel strain of virus such as influenza produces pandemics which increase illness, death and disruption in the countries. Spanish flu in 1918, Asian flu in 1957, Hong Kong flu in 1968 and swine flu in 2009 were known pandemic which had various characteristics in terms of morbidity and mortality. A current pandemic is caused by novel corona virus originated from China. COVID-19 pandemic is very similar to Spanish, Hong Kong, Asian and swine influenza pandemics in terms of spreading to world by the mobilized people. Burden of pandemic is considered in terms of disease transmissibility and the …

The Ethical Justification Of Increasing Awareness Of Preventive Medicine Among Healthcare Professionals, Patients And The General Public In The United States, Karishma Ether Moazzam

Electronic Theses and Dissertations

While practiced for centuries, preventive medicine has received increased attention during the recent times. Preventive medicine has a distinct mission to protect, promote, and maintain health as well as to prevent diseases, disabilities, and premature deaths. It aims to fulfill its mission through the combined form of clinical intervention and health promotion. In the recent years, preventive medicine has begun to lean more towards the clinical interventions, taking away from the health promotion. This imbalance has caused preventive medicine to lose its effectiveness in fulfilling its mission. One of the leading causes for such imbalance is the lack of proper …

Progression Magazine, 2019 Fall/Winter, Coastal Carolina University

Progression Magazine

Magazine of the College of Science at Coastal Carolina University.

The Impact Of The 2010 Affordable Care Act On Reducing Racial/Ethnic Disparties In Primary Care Acess And The Delivery Of Diabetes Preventive Care In The United States, Adrianna Nava

Graduate Doctoral Dissertations

A key focus of the 2010 Patient Protection and Affordable Care Act (ACA) was to improve access to healthcare services in the United States (U.S.) (Stolberg & Pear, 2010). The research purpose was to assess the impact of the ACA’s Medicaid expansion and insurance subsidies on reducing racial/ethnic disparities in coverage, access and the delivery of primary care services, specifically diabetes prevention. Diabetes disproportionately affects minority populations, with inequities reported in the delivery of diabetes care to minorities (Chow, Foster, Gonzalez & McIver, 2012). The Modified Quality Health Outcomes Model was used to guide this research. Statistical analyses were conducted …

Preface For Special Section On Archaeoparasitology: A Global Perspective On Ancient Parasites And Current Research Projects, Jong Yil Chai, Min Sea, Karl Reinhard, Dong Hoon Shin

Karl Reinhard Publications

Archaeoparasitological research has rapidly developed in recent years, entering a new stage of improved understanding of our ancestors’ parasitic infections across the world. This progress is based on a variety of recently developed research techniques. During a period of rapid innovation since 2016, there has been no much opportunity for parasitologists to gather and share in-depth views about this novel research field. This was remedied by the 14th International Congress of Parasitology (ICOPA) held in Korea (Aug. 19-24, 2018; EXCO, Daegu). For archaeoparasitologists, ICOPA provided a unique opportunity to gather and exchange research and ideas. The participation was unprecedented in …

Pinworm Infection At Salmon Ruins And Aztec Ruins: Relation To Pueblo Iii Regional Violence, Karl Reinhard, Morgana Camacho

Karl Reinhard Publications

The study of coprolites has been a theme of archaeology in the American Southwest. A feature of archaeoparasitology on the Colorado Plateau is the ubiquity of pinworm infection. As a crowd parasite, this ubiquity signals varying concentrations of populations. Our recent analysis of coprolite deposits from 2 sites revealed the highest prevalence of infection ever recorded for the region. For Salmon Ruins, the deposits date from AD 1140 to 1280. For Aztec Ruins, the samples can be dated by artifact association between AD 1182-1253. Both sites can be placed in the Ancestral Pueblo III occupation (AD 1100-1300), which included a …

Improving Team-Based Decision Making Using Data Analytics And Informatics: Protocol For A Collaborative Decision Support Design, Don Roosan, Anandi Law, Mazharul Karim, Moom Roosan

Pharmacy Faculty Articles and Research

Background: According to the September 2015 Institute of Medicine report, Improving Diagnosis in Health Care, each of us is likely to experience one diagnostic error in our lifetime, often with devastating consequences. Traditionally, diagnostic decision making has been the sole responsibility of an individual clinician. However, diagnosis involves an interaction among interprofessional team members with different training, skills, cultures, knowledge, and backgrounds. Moreover, diagnostic error is prevalent in the interruption-prone environment, such as the emergency department, where the loss of information may hinder a correct diagnosis.

Objective: The overall purpose of this protocol is to improve team-based diagnostic …

Antibiotics Overuse And Bacterial Resistance, Mir Saleem, Brett Deters, Adam De La Bastide, Martha Korzen

Biology Faculty Articles

Antibiotic usage has become very widespread, as they are used to treat so many infectious diseases today. Antimicrobial agents exert their actions via different mechanisms including blockage of cell wall synthesis, interference of protein and/or nucleic acid synthesis, interruption of cell membrane structure, and inhibition of a metabolic pathway. The treatment of bacterial infections with antimicrobial agents has become more difficult due to the capability of bacteria to develop resistance to antibiotics. Erroneous diagnosing, misconceptions, and improper physician-patient dynamics have led to overuse of antibiotics and the emergence of drug-resistant bacteria. Bacterial colonies have been shown to confer advantageous genetic …

From The Human To The Planetary: Speculative Futures Of Care, Miriam Ticktin

Publications and Research

This is largely a theoretical, speculative essay that takes on the question of what ‘care’ looks like at a moment when climate change is increasingly taking center stage in public and political discussions. Starting with two new practices, namely, humanitarian care for nonhumans and One Health collaborations, I seek to determine what forms of political care can incorporate the well-being of future generations and future iterations of the earth. After an exploration of One Health as an approach to planetary care, I ask what its parts enable us to think, despite its limitations; I focus on the new human-nonhuman assemblages …

Legionnaires' Disease, A Rising Occurrence In The United States, Jennifer Harklerode, Olivia Henton, Myranda Smith, Rebecca Worden, Andrew Roecker

Pharmacy and Wellness Review

Legionella pneumophila, a microscopic bacterium usually responsible for a number of illnesses and fatalities, can eliminate a local population, a region or even a nation. In 1976, L. pneumophila was first discovered due to a number of cases presenting with pneumonia-like symptoms. These cases occurred in an isolated population attending an American Legion convention in Philadelphia, Pennsylvania, therefore lending to the name Legionella. Usually found in aquatic environments such as lakes, streams, cooling towers, air conditioning systems and hot tubs, its ability to thrive in artificial and natural environments makes it an ideal bacterium. L. pneumophila can be transmitted via …

Sisters Of The Caliphate: Media And The Women Of Isis, Kathleen German, Rosemary Pennington

Journal of Vincentian Social Action

Women have long been viewed as the “weaker sex”–more peace-loving and passive than men. However, clashes in Sri Lanka and Northern Ireland have shown that women are both willing and able to participate in violent conflict (Alison, 2004; Cheldelin & Eliatamby, 2011). We will specifically examine the recruitment to and roles of women in the Islamic State through an examination of the scholarship on female fighters, in order to contextualize the women of ISIS. We conclude with a suggestion that scholars and others interested in the experience of women in conflict move away from overly simplistic framings which suggest women …

Disinformation As Warfare In The Digital Age: Dimensions, Dilemmas, And Solutions, Minna Aslama Horowitz

Journal of Vincentian Social Action

Disinformation as warfare in the digital age may not be so different than any other type of warfare; wars are fought for power, and some benefit economically while the vulnerable suffer the most. The vast majority of conflicts today are not fought by nation states and their armies; increasingly, they are fought not with conventional weapons but with words. A specific sort of weaponry—“fake news” and viral disinformation—has been at the center of policy discussions, public debates, and academic analyses in recent years. Everyone who is active on digital platforms can be responsible in the simplest of ways: not lashing …

Introduction: Wars, Conflicts, And The Marginalization Of Dissent, Tuija Parikka, Basilio G. Monteiro, Sejal Singh

Journal of Vincentian Social Action

Conflicts, wars, and crisis, unfortunately, abound, transform, and become metastasized in unexpected ways. The vast majority of armed conflicts today are not fought by nation states and their armies but rather informal entities, such as gangs and warlords using small arms, improvised weapons, and media technologies. Few, usually poor resource regions, get global attention, thus deprived of political will and economic resources needed to resolve the conflicts. As women and other minorities are becoming primary targets and suffering unprecedented casualties, they are profoundly affected by practices and cultures of warring, yet often remain voiceless in the global arena.This special issue …

Toc

Journal of Vincentian Social Action

No abstract provided.

Human Ecology, Spring/Summer 2016, Issue 34

Sustain Magazine

No abstract provided.

Peripheral Vascular Injuries - Not To Miss Or Mess Them!, Zia Ur Rehman

Department of Surgery Docs

No abstract provided.