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Male Infertility: A Retrospective Review Of Laboratory Charts At A Tertiary Teaching Hospital In Nairobi City County, Festus Mulakoli, Doris Machaki, Abednego Ongeso, Maureen Akolo, Ruth Wagathu May 2024

Male Infertility: A Retrospective Review Of Laboratory Charts At A Tertiary Teaching Hospital In Nairobi City County, Festus Mulakoli, Doris Machaki, Abednego Ongeso, Maureen Akolo, Ruth Wagathu

School of Nursing & Midwifery, East Africa

Background: Globally, approximately 50 million couples experience one form of infertility, and 10 million cases of subfertility have been reported in sub-Saharan Africa. Infertility is characterized by a lack of clinical conception among couples who live together for more than one year with regular coitus, without the use of contraception. Factors related to fertility vary by sex and geographical region. These factors include age, lifestyle, infectious diseases, and genetic disorders. In African culture, children are considered a simple inheritance and a measure of masculinity, so efforts are needed to address the growing problem of male infertility in this context. …


Stillbirth Mortality By Robson Ten-Group Classification System: A Cross-Sectional Registry Of 80 663 Births From 16 Hospital In Sub-Saharan Africa, Claudia Hanson, Kristi Annerstedt, Maria Alsina, Muzdalfat Abeid, Hussein Kidanto, Helle Alvesson, Andrea Pembe, Peter Waiswa, Jean-Paul Dossou, Effie Chipeta May 2024

Stillbirth Mortality By Robson Ten-Group Classification System: A Cross-Sectional Registry Of 80 663 Births From 16 Hospital In Sub-Saharan Africa, Claudia Hanson, Kristi Annerstedt, Maria Alsina, Muzdalfat Abeid, Hussein Kidanto, Helle Alvesson, Andrea Pembe, Peter Waiswa, Jean-Paul Dossou, Effie Chipeta

Centre of Excellence in Women and Child Health

Objective To assess stillbirth mortality by Robson ten-group classification and the usefulness of this approach for understanding trends.

Design Cross-sectional study.

Setting Prospectively collected perinatal e-registry data from 16 hospitals in Benin, Malawi, Tanzania and Uganda.

Population All women aged 13–49 years who gave birth to a live or stillborn baby weighting >1000 g between July 2021 and December 2022.

Methods We compared stillbirth risk by Robson ten-group classification, and across countries, and calculated proportional contributions to mortality.

Main outcome measures Stillbirth mortality, defined as antepartum and intrapartum stillbirths.

Results We included 80 663 babies born to 78 085 women; …


Modeling The Transmission Dynamics Of Tuberculosis In Humans, Farida Kisinda, Joshua A. Mwasunda, Mbwiga S. Aloni Apr 2024

Modeling The Transmission Dynamics Of Tuberculosis In Humans, Farida Kisinda, Joshua A. Mwasunda, Mbwiga S. Aloni

Tanzania Journal of Science

Tuberculosis (TB) is a major threat to human health particularly in most of developing countries. In this article, we formulate and analyze a deterministic model for the transmission dynamics of pulmonary and extra-pulmonary tuberculosis. The next generation method is employed to find the basic reproduction number which helps to determine whether TB clears or persists in the human population. Global stability of model equilibria is done through Lyapunov functions whereas the normalized forward sensitivity index method is adopted to determine parameters that drive tuberculosis. Analysis shows that both TB free and endemic equilibria exist. The TB free equilibrium is globally …


Prevalence And Predictors Of Cesarean Delivery In A Tertiary Hospital In Taraba State, Nigeria, Olateju Alao Bamigbala, Ayodeji Oluwatobi Ojetunde, Maza Tanko Apr 2024

Prevalence And Predictors Of Cesarean Delivery In A Tertiary Hospital In Taraba State, Nigeria, Olateju Alao Bamigbala, Ayodeji Oluwatobi Ojetunde, Maza Tanko

Tanzania Journal of Science

A cesarean section (CS) is a surgical technique in which a baby is delivered through an abdomen and uterine incision following fetal viability. It is imperative to identify the factors that influence the use of CS to reduce the needless use of this life-saving procedure and increase its availability for those who need it most. Therefore, this study assesses the prevalence and predictors of cesarean delivery in a tertiary hospital in Taraba state, Nigeria. Information of pregnant women who came for delivery to Federal Medical Center, Jalingo, Taraba state Nigeria from August 2021 to August 2023 was collected. Binary Logistic …


Modelling The Combined Use Of Long-Lasting Insecticidal Nets And Insecticides Zooprophylaxis Against The Resilience Of Anopheles Arabiensis For Effective Malaria Control, Watson Levens Apr 2024

Modelling The Combined Use Of Long-Lasting Insecticidal Nets And Insecticides Zooprophylaxis Against The Resilience Of Anopheles Arabiensis For Effective Malaria Control, Watson Levens

Tanzania Journal of Science

Malaria is a significant public health concern, especially in tropical regions. It remains endemic in many areas where malaria mosquitoes are prevalent. This study investigates the viability of insecticide zooprophylaxis (IZ) in conjunction with Long Lasting Insecticidal Nets (LLINs) as a strategic approach to combat malaria transmission, particularly in regions dominated by zoophagic vectors. Through the presentation and analysis of a mathematical model that integrates IZ and LLINs for the control of Anopheles arabiensis (An. arabiensis), the research underscores IZ's role in reducing zoophagic vector populations and enhancing malaria control efforts. Notably, the study reveals that achieving comprehensive coverage of …


Dispelling The Malaria-Typhoid Co-Infection Myth In Nigeria. A Literature Review, Olawale Akinola Apr 2024

Dispelling The Malaria-Typhoid Co-Infection Myth In Nigeria. A Literature Review, Olawale Akinola

Dartmouth Library Staff Publications

Malaria and typhoid fever are public health concerns in Nigeria, with high prevalence rates. The perception of a widespread co-infection between these diseases may be misleading, due to limitations in diagnostic methods, particularly the Widal test for typhoid fever. This literature review examines the prevalence of malaria-typhoid co-infection in Nigeria and identifies factors contributing to misdiagnosis, including non-specific symptoms, limited diagnostic resources, and the diagnostic accuracy of tests employed. Additionally, the review discusses the implications of misdiagnosis, such as the overuse of broad-spectrum antibiotics leading to a rising incidence of antimicrobial resistance. Strategies to address this issue are explored, emphasizing …


Incidental Actinomycosis In A 44-Year-Old Female During Total Abdominal Hysterectomy For Abnormal Uterine Bleeding: A Case Report, Willbroad Kyejo, Ally Zain Ismail, Abduel Kitua, Gregory Ntiyakunze, Munawar Kaguta, Ally Mwawnga Apr 2024

Incidental Actinomycosis In A 44-Year-Old Female During Total Abdominal Hysterectomy For Abnormal Uterine Bleeding: A Case Report, Willbroad Kyejo, Ally Zain Ismail, Abduel Kitua, Gregory Ntiyakunze, Munawar Kaguta, Ally Mwawnga

Family Medicine, East Africa

Actinomycosis, a rare chronic bacterial infection caused by Actinomyces species, presents diagnostic challenges due to diverse clinical presentations. This report presents a case of peritoneal actinomycosis incidentally discovered during a total abdominal hysterectomy in a 44-year-old female with refractory abnormal uterine bleeding and a history of long-term intrauterine contraceptive device use. The patient presented with persistent abnormal uterine bleeding despite conservative management. Intraoperative findings during total abdominal hysterectomy revealed peritoneal involvement, prompting histopathological evaluation confirming actinomycosis. This case highlights diagnostic complexities associated with actinomycosis, emphasizing the significance of histopathological confirmation. Postoperative management with antibiotics demonstrated favorable outcomes, supporting their efficacy …


Incidental Actinomycosis In A 44-Year-Old Female During Total Abdominal Hysterectomy For Abnormal Uterine Bleeding: A Case Report, Willbroad Kyejo, Allyzain Ismail, Abduel Kitua, Brenda Moshi, Gregory Ntiyakunze, Munawar Kaguta, Ally Mwanga Apr 2024

Incidental Actinomycosis In A 44-Year-Old Female During Total Abdominal Hysterectomy For Abnormal Uterine Bleeding: A Case Report, Willbroad Kyejo, Allyzain Ismail, Abduel Kitua, Brenda Moshi, Gregory Ntiyakunze, Munawar Kaguta, Ally Mwanga

Internal Medicine, East Africa

Actinomycosis, a rare chronic bacterial infection caused by Actinomyces species, presents diagnostic challenges due to diverse clinical presentations. This report presents a case of peritoneal actinomycosis incidentally discovered during a total abdominal hysterectomy in a 44-year-old female with refractory abnormal uterine bleeding and a history of long-term intrauterine contraceptive device use. The patient presented with persistent abnormal uterine bleeding despite conservative management. Intraoperative findings during total abdominal hysterectomy revealed peritoneal involvement, prompting histopathological evaluation confirming actinomycosis. This case highlights diagnostic complexities associated with actinomycosis, emphasizing the significance of histopathological confirmation. Postoperative management with antibiotics demonstrated favorable outcomes, supporting their efficacy …


Leveraging Ai And Machine Learning To Develop And Evaluate A Contextualized User-Friendly Cough Audio Classifier For Detecting Respiratory Diseases: Protocol For A Diagnostic Study In Rural Tanzania, Kahabi Isangula, Rogers John Haule Apr 2024

Leveraging Ai And Machine Learning To Develop And Evaluate A Contextualized User-Friendly Cough Audio Classifier For Detecting Respiratory Diseases: Protocol For A Diagnostic Study In Rural Tanzania, Kahabi Isangula, Rogers John Haule

School of Nursing & Midwifery, East Africa

Background:

Respiratory diseases, including active tuberculosis (TB), asthma, and chronic obstructive pulmonary disease (COPD), constitute substantial global health challenges, necessitating timely and accurate diagnosis for effective treatment and management.

Objective:

This research seeks to develop and evaluate a noninvasive user-friendly artificial intelligence (AI)–powered cough audio classifier for detecting these respiratory conditions in rural Tanzania.

Methods:

This is a nonexperimental cross-sectional research with the primary objective of collection and analysis of cough sounds from patients with active TB, asthma, and COPD in outpatient clinics to generate and evaluate a noninvasive cough audio classifier. Specialized cough sound recording devices, designed to be …


Mushroom Composition Across An Elevational Gradient During The 2024 Wet Season In Mazumbai Forest Reserve, Tanzania, Christopher Brady Apr 2024

Mushroom Composition Across An Elevational Gradient During The 2024 Wet Season In Mazumbai Forest Reserve, Tanzania, Christopher Brady

Independent Study Project (ISP) Collection

Mushrooms are key bioindicators that contribute greatly to ecological health, and their diversity is indicative of a healthy ecosystem. However, even with the vital role they play in ecological health, there are few studies which measure the diversity of mushrooms in Mazumbai Forest Reserve (MFR), Tanzania, Africa, and none which focus on diversity along the elevational gradient within the reserve (1300-1900m). This study measures the diversity and equitability of mushrooms growing in six elevational zones within MFR during the rainy season of 2024. A species checklist of mushrooms growing in MFR during the 2024 rainy season was created, tracking the …


Viral Epitope Scanning Reveals Correlation Between Seasonal Hcovs And Sars-Cov-2 Antibody Responses Among Cancer And Non-Cancer Patients, Salum J. Lidenge, Dicle Yalcin, Sydney J. Bennett, Owen Ngalamika, Brenda B. Kweyamba, Chacha J. Mwita, For Yue Tso, Julius Mwaiselage, John T. West, Charles Wood Mar 2024

Viral Epitope Scanning Reveals Correlation Between Seasonal Hcovs And Sars-Cov-2 Antibody Responses Among Cancer And Non-Cancer Patients, Salum J. Lidenge, Dicle Yalcin, Sydney J. Bennett, Owen Ngalamika, Brenda B. Kweyamba, Chacha J. Mwita, For Yue Tso, Julius Mwaiselage, John T. West, Charles Wood

School of Medicine Faculty Publications

Seasonal coronaviruses (HCoVs) are known to contribute to cross-reactive antibody (Ab) responses against SARS-CoV-2. While these responses are predictable due to the high homology between SARS-CoV-2 and other CoVs, the impact of these responses on susceptibility to SARS-CoV-2 infection in cancer patients is unclear. To investigate the influence of prior HCoV infection on anti-SARS-CoV-2 Ab responses among COVID-19 asymptomatic individuals with cancer and controls without cancers, we utilized the VirScan technology in which phage immunoprecipitation and sequencing (PhIP-seq) of longitudinal plasma samples was performed to investigate high-resolution (i.e., epitope level) humoral CoV responses. Despite testing positive for anti-SARS-CoV-2 Ab in …


Abdominal Wall Endometriosis In Cesarean Scar: A Case Report, Willbroad Kyejo, Brenda Moshi, Euphraim Massanga, Gregory Ntiyakunze, Miriam Mgonja, Munawar Kaguta, Ernest Mdachi Mar 2024

Abdominal Wall Endometriosis In Cesarean Scar: A Case Report, Willbroad Kyejo, Brenda Moshi, Euphraim Massanga, Gregory Ntiyakunze, Miriam Mgonja, Munawar Kaguta, Ernest Mdachi

Family Medicine, East Africa

Abdominal wall endometriosis refers to the presence of endometrial tissue within surgical scars, most commonly occurring following gynecological procedures such as cesarean sections. This case report presents a rare case of abdominal wall endometriosis in a cesarean scar. The patient, a 32-year-old woman with a history of two previous cesarean sections, presented with cyclic pain and swelling in the lower abdominal region. Physical examination revealed a tender, well-defined mass within the cesarean scar. Surgical excision of the mass was performed, and histopathological examination confirmed the presence of endometrial tissue. This case highlights the importance of considering abdominal wall endometriosis in …


Entrance Surface Air Kerma To Patients During Digital Radiographic Examinations In Tanzania, Atumaini Makoba, Ahmed Jusabani, Wilbroad Muhogora, Abdallah Kileo, Musa Ndukeki, Huruma Mammba, Hilda Makungu, Haika Maro, Erick Onoka, Miguta Ngulimi Mar 2024

Entrance Surface Air Kerma To Patients During Digital Radiographic Examinations In Tanzania, Atumaini Makoba, Ahmed Jusabani, Wilbroad Muhogora, Abdallah Kileo, Musa Ndukeki, Huruma Mammba, Hilda Makungu, Haika Maro, Erick Onoka, Miguta Ngulimi

Imaging & Diagnostic Radiology, East Africa

The aim of this study was to determine the entrance surface air kerma (ESAK) in adult patients during digital radiography and to evaluate the optimisation potential in five common X-ray examinations in Tanzania. Based on a sample of 240–610 patients, ESAK was estimated using X-ray tube output measurements, patient information and backscatter factors. The results show that the mean ESAK values were higher or comparable to data from the literature. The diagnostic reference values of ESAK for digital radiography were 0.31 mGy (chest PA), 4 mGy (lumbar spine AP), 5.4 mGy (lumbar spine LAT), 3.8 mGy (abdomen AP) and 2.4 …


A Case Of Parkinsonian Symptoms Secondary To Chronic Subdural Hematoma, Willbroad Kyejo, Frank Swai, Clement Mugisha, Philip Adebayo Mar 2024

A Case Of Parkinsonian Symptoms Secondary To Chronic Subdural Hematoma, Willbroad Kyejo, Frank Swai, Clement Mugisha, Philip Adebayo

Internal Medicine, East Africa

Chronic subdural hematoma is a known neurosurgical entity often associated with a spectrum of neurological manifestations. While primarily recognized for its characteristic accumulation of blood between the dura mater and arachnoid membrane, emerging literature suggests a rare association between chronic subdural hematoma and Parkinsonian symptoms. This report aims to underscore this unique neurological relationship by presenting a case of a 70-year-old male who developed Parkinsonism following chronic subdural hematoma post-head trauma. This case underscores the rare association between chronic subdural hematoma and Parkinsonian symptoms, emphasizing the importance of timely diagnosis and intervention in managing such cases.


Dental Caries In Children With Sickle Cell Disease And Its Association With The Use Of Hydroxyurea And Penicillin Prophylaxis In Dar Es Salaam, Irene Kida Minja, Evarist Mulyahela Wilson, Ferdinand M. Machibya, Agnes Jonathan, Fortunata Cornel, Paschal Ruggajo, Julie Makani, Ferdinand M. Machibya Mar 2024

Dental Caries In Children With Sickle Cell Disease And Its Association With The Use Of Hydroxyurea And Penicillin Prophylaxis In Dar Es Salaam, Irene Kida Minja, Evarist Mulyahela Wilson, Ferdinand M. Machibya, Agnes Jonathan, Fortunata Cornel, Paschal Ruggajo, Julie Makani, Ferdinand M. Machibya

Internal Medicine, East Africa

Purpose.

This comparative study sets out to report dental caries status among individuals with Sickle Cell Disease (HbSS) against those with sickle cell trait (HbSA) and those without the disease (HbAA) as controls. The study further assessed the impact of penicillin chemoprophylaxis and hydroxyurea use on dental caries among Sickle Cell Disease participants.

Methods.

This was a comparative cross-sectional study in which 93 children aged 30 to 60 months were recruited. There were 60 participating children who had SCD (HbSS), 17 with SCD trait (HbAS) and 16 were without SCD or SC trait (HbAA). A questionnaire was used to record …


National Non-Communicable Diseases Conferences- A Platform To Inform Policies And Practices In Tanzania, Davis E. Amani, Harrieth P. Ndumwa, Jackline E. Ngowi, Belinda J. Njiro, Castory Munishi, Erick A. Mboya, Doreen Mloka, Amani I. Kikula, Emmanuel Balandya, Paschal Ruggajo Mar 2024

National Non-Communicable Diseases Conferences- A Platform To Inform Policies And Practices In Tanzania, Davis E. Amani, Harrieth P. Ndumwa, Jackline E. Ngowi, Belinda J. Njiro, Castory Munishi, Erick A. Mboya, Doreen Mloka, Amani I. Kikula, Emmanuel Balandya, Paschal Ruggajo

Internal Medicine, East Africa

Background:

Non-communicable diseases (NCDs) arise from diverse risk factors with differences in the contexts and variabilities in regions and countries. Addressing such a complex challenge requires local evidence. Tanzania has been convening stakeholders every year to disseminate and discuss scientific evidence, policies, and implementation gaps, to inform policy makers in NCDs responses. This paper documents these dissemination efforts and how they have influenced NCDs response and landscape in Tanzania and the region.

Methods:

Desk review was conducted through available MOH and conference organizers’ documents. It had both quantitative and qualitative data. The review included reports of the four NCDs conferences, …


Abdominal Wall Endometriosis In Cesarean Scar: A Case Report, Willbroad Kyejo, Brenda Moshi, Euphraim Massanga, Gregory Ntiyakunze, Miriam Mgonja, Munawar Kaguta, Ernest Mdachi Mar 2024

Abdominal Wall Endometriosis In Cesarean Scar: A Case Report, Willbroad Kyejo, Brenda Moshi, Euphraim Massanga, Gregory Ntiyakunze, Miriam Mgonja, Munawar Kaguta, Ernest Mdachi

Obstetrics and Gynaecology, East Africa

Abdominal wall endometriosis refers to the presence of endometrial tissue within surgical scars, most commonly occurring following gynecological procedures such as cesarean sections. This case report presents a rare case of abdominal wall endometriosis in a cesarean scar. The patient, a 32-year-old woman with a history of two previous cesarean sections, presented with cyclic pain and swelling in the lower abdominal region. Physical examination revealed a tender, well-defined mass within the cesarean scar. Surgical excision of the mass was performed, and histopathological examination confirmed the presence of endometrial tissue. This case highlights the importance of considering abdominal wall endometriosis in …


Predictors Of Prior Hiv Testing And Acceptance Of A Community-Based Hiv Test Offer Among Male Bar Patrons In Northern Tanzania, Deng B. Madut, Preeti Manavalan, Antipas Mtalo, Timothy Peter, Jan Ostermann, Bernard Njau, Nathan M. Thielman Feb 2024

Predictors Of Prior Hiv Testing And Acceptance Of A Community-Based Hiv Test Offer Among Male Bar Patrons In Northern Tanzania, Deng B. Madut, Preeti Manavalan, Antipas Mtalo, Timothy Peter, Jan Ostermann, Bernard Njau, Nathan M. Thielman

Faculty Publications

Community-based HIV testing offers an alternative approach to encourage HIV testing among men in sub-Saharan Africa. In this study, we evaluated a community-based HIV testing strategy targeting male bar patrons in northern Tanzania to assess factors predictive of prior HIV testing and factors predictive of accepting a real-time HIV test offer. Participants completed a detailed survey and were offered HIV testing upon survey completion. Poisson regression was used to identify prevalence ratios for the association between potential predictors and prior HIV testing or real-time testing uptake. Of 359 participants analyzed, the median age was 41 (range 19–82) years, 257 (71.6%) …


Inequalities In Use Of Hospitals For Childbirth Among Rural Women In Sub-Saharan Africa: A Comparative Analysis Of 18 Countries Using Demographic And Health Survey Data., Manuela Straneo, Claudia Hanson, Thomas Van Den Akker, Bosede Afolabi, Anteneh Asefa, Alexandre Delamou, Mardieh Dennis, Luis Gadama, Nyika Mahachi, Welcome Mlilo Jan 2024

Inequalities In Use Of Hospitals For Childbirth Among Rural Women In Sub-Saharan Africa: A Comparative Analysis Of 18 Countries Using Demographic And Health Survey Data., Manuela Straneo, Claudia Hanson, Thomas Van Den Akker, Bosede Afolabi, Anteneh Asefa, Alexandre Delamou, Mardieh Dennis, Luis Gadama, Nyika Mahachi, Welcome Mlilo

Centre of Excellence in Women and Child Health

Introduction; Rising facility births in sub-Saharan Africa (SSA) mask inequalities in higher-level emergency care— typically in hospitals. Limited research has addressed hospital use in women at risk of or with complications, such as high parity, linked to poverty and rurality, for whom hospital care is essential. We aimed to address this gap, by comparatively assessing hospital use in rural SSA by wealth and parity.

Methods; Countries in SSA with a Demographic and Health Survey since 2015 were included. We assessed rural hospital childbirth stratifying by wealth (wealthier/poorer) and parity (nulliparity/high parity≥5), and their combination. We computed percentages, 95% CIs and …


Clinical Characteristics And Outcomes Of Patients With Idiopathic Intracranial Hypertension In East Africa: A Retrospective Cross-Sectional Study, Zian Muikamba Jan 2024

Clinical Characteristics And Outcomes Of Patients With Idiopathic Intracranial Hypertension In East Africa: A Retrospective Cross-Sectional Study, Zian Muikamba

Master of Internal Medicine

Introduction; Idiopathic intracranial hypertension (IIH) is a neurological condition characterized by elevated intracranial cerebrospinal fluid (CSF) pressure without demonstratable evident causes. The mechanisms leading to a particular predilection for women of childbearing age who are overweight and obese or who have recent rapid weight changes remain imprecisely described. The Modified Dandy criteria is used for diagnosis and includes-clinical symptoms, papilledema, lumbar puncture (LP) opening pressure, and neuroimaging. If undiagnosed, it can progress to disabling irreversible visual loss. Weight loss is useful in addition to medical therapy in treating the condition. Data in Sub-Saharan Africa is scarce.

Methods; This study described …


Mandatory Second Opinion To Reduce Caesarean Section Rate Among Low-Risk Pregnant Women At A Private Tertiary Hospital: An Analysis Using Who Robson Classification., Gregory Ntiyakunze Jan 2024

Mandatory Second Opinion To Reduce Caesarean Section Rate Among Low-Risk Pregnant Women At A Private Tertiary Hospital: An Analysis Using Who Robson Classification., Gregory Ntiyakunze

Master of Obstetrics and Gynecology

v> The caesarean section rate has increased globally, even among low-risk obstetric deliveries. Consequently, mothers and babies are exposed to potential complications associated with caesarean sections. Therefore, the World Health Organization has introduced measures to reduce unnecessary caesarean sections, including a globally accepted classification system for all deliveries Robson's system and recommended safe non-medical interventions, such as mandatory second opinions prior to caesarean sections


Knowledge And Perception Of Hand Hygiene And Associated Factors Among Final Year Medical And Nursing Students In Dar Es Salaam Tanzania, Anthony Baltazary Ngowi Jan 2024

Knowledge And Perception Of Hand Hygiene And Associated Factors Among Final Year Medical And Nursing Students In Dar Es Salaam Tanzania, Anthony Baltazary Ngowi

Master of Obstetrics and Gynecology

Hand hygiene, when practiced correctly and consistently is a simple and effective

method to prevent healthcare associated infections. These infections are acquired during a patients’ hospital stay and pose a major worldwide public health problem. The knowledge and practices related to hand hygiene among health workers need to be instilled early on during their training to develop a culture of correct and consistent practice. Existing literature has explored hand hygiene among health workers but very few studies have looked at it amongst medical and nursing students, who are the healthcare workers of tomorrow. This study aimed to assess hand hygiene …


Challenges In Post Graduate General Surgery Training In Tanzania: A Trainee’S Perspective, Shabbir Adamjee Jan 2024

Challenges In Post Graduate General Surgery Training In Tanzania: A Trainee’S Perspective, Shabbir Adamjee

Master of Surgery

v>

General Surgery residency training is a complex vigorous program which includes long working hours and complex surgical cases, in order to develop and attain the knowledge and the skills the trainee needs by the end of the program. Worldwide, general surgery programs have high attrition rates and residents have identified challenges which may be work related, related to social wellbeing and/or the residency program structure. Tanzania has public and private institutions providing general surgery residency training and although most have a quality assessment program the data is not readily available. Each institution has its personalized curriculum with its unique …


Microbial Profile And Antimicrobial Resistance Patterns Of Surgical Intra-Abdominal Infections At A Tertiary Hospital In Tanzania A Retrospective Cross-Sectional Study, Abduel Julius Kitua Jan 2024

Microbial Profile And Antimicrobial Resistance Patterns Of Surgical Intra-Abdominal Infections At A Tertiary Hospital In Tanzania A Retrospective Cross-Sectional Study, Abduel Julius Kitua

Master of Surgery

v>

Among infections of surgical importance, intra-abdominal infections prevail among the most common in surgical patients with considerable morbidity and mortality. The ever-rising microbial resistance to commonly available antibiotics and geographical variations in microbial profile and resistance patterns poses a challenge to the management of these surgical infections of abdominal origin. The aim of this study was to evaluate microbiological characteristics and antibiotic susceptibility of isolates from intra-abdominal infections at a tertiary hospital in Tanzania and how these influence early treatment outcomes.


Factors Associated With Antiretroviral Drug Resistance Mutations Among Plhiv Failing To Achieve Virological Suppression On Second Line Treatment In Tanzania., Mabula M. Mabelele Jan 2024

Factors Associated With Antiretroviral Drug Resistance Mutations Among Plhiv Failing To Achieve Virological Suppression On Second Line Treatment In Tanzania., Mabula M. Mabelele

Master of Internal Medicine

v> Human Immunodeficiency Virus / Acquired Immunodeficiency Syndrome (HIV/AIDS) is a major public health problem affecting an estimated 38.4 million people globally, with the (54%) of them being from the Eastern and Southern African regions. Despite progress in the availability of multiple classes of antiretroviral drugs and early initiation of treatment with cART, many patients still fail therapy in the first and second-line regimens due to drug resistance driven by continuous acquisition of drug resistance mutation (DRMs). DRMs are high among adults failing treatment regimens, ranging between 50-97%.


The Anthropometric Determinants Of Peak Expiratory Flow Rate Among Children In Dar Es Salaam, Tanzania, Willbroad Kyejo, Nancy Matillya, Neelam Ismail, Gloria Gachocha, Hajaj Salum, Rosebella Iseme, Mariam Noorani Jan 2024

The Anthropometric Determinants Of Peak Expiratory Flow Rate Among Children In Dar Es Salaam, Tanzania, Willbroad Kyejo, Nancy Matillya, Neelam Ismail, Gloria Gachocha, Hajaj Salum, Rosebella Iseme, Mariam Noorani

Family Medicine, East Africa

Background: Peak expiratory flow rate (PEFR) is an important tool for assessing lung function, which can be affected by environmental and physical factors such as altitude, nutrition, genetics, age, height, and weight. Conducting a study to assess the correlation between peak expiratory flow rate and anthropometric measurements in Tanzanian schoolchildren is crucial to derive a population-specific prediction formula and further simplify respiratory health assessment.

Methods: This cross-sectional study was conducted in a single center private primary and secondary school in Dar es Salaam, Tanzania using data from an asthma screening camp. Variables of interest were height, weight, Body Mass Index …


One Cime | Year In Review 2024, Cime Jan 2024

One Cime | Year In Review 2024, Cime

Centre for Innovation in Medical Education (CIME) Archives

  • Honouring Prince Karim Aga Khan IV Our Founding Chancellor
  • Hear from Our Directors
  • The Impact of SIMPACT
  • Gamified Learning at Simulation Week
  • Updates from Karachi
  • Updates from Nairobi
  • SeeMe Around the Globe
  • Research at CIME
  • The Dream Team


Manual Qualitative Data Coding Using Ms Word For Students And Early Career Researchers In Resource-Constrained Settings, Kahabi Isangula, Susan Kelly, Joyce Wamoyi Jan 2024

Manual Qualitative Data Coding Using Ms Word For Students And Early Career Researchers In Resource-Constrained Settings, Kahabi Isangula, Susan Kelly, Joyce Wamoyi

School of Nursing & Midwifery, East Africa

In recent years, the field of qualitative data collection, management, and analysis has undergone significant evolution, with researchers worldwide increasingly leveraging technological advancements to streamline and simplify their practices. Despite the advantages of using qualitative data coding software, several challenges persist, particularly in resource-constrained settings. Issues such as the high cost of software licenses, the time required to learn and use these tools, and the complexity of advanced features often hinder researchers, especially students and early career researchers in low-income contexts, and contribute to the generation of poor-quality research evidence. This paper aims to provide a simplified, step-by-step guide to …


A Qualitative Exploration Of Nurses’ And Midwives’ Experiences In Designated Covid-19 Healthcare Facilities In Rural And Urban Tanzania, Kahabi Isangula, Lucy Kisaka, Loveluck Mwasha Jan 2024

A Qualitative Exploration Of Nurses’ And Midwives’ Experiences In Designated Covid-19 Healthcare Facilities In Rural And Urban Tanzania, Kahabi Isangula, Lucy Kisaka, Loveluck Mwasha

School of Nursing & Midwifery, East Africa

Background:

Frontline healthcare providers, particularly nurses and midwives, are at higher risk of COVID-19 infection due to frequent patient contact. However, studies examining their experiences, particularly in low-income countries like Tanzania, are limited.

Objective:

This study aimed to explore the experiences of nurses and midwives providing care in COVID-19-designated healthcare facilities in selected regions of Tanzania.

Methods:

A qualitative descriptive approach was used to investigate the experiences of nurses and midwives in COVID-19 care. In-depth interviews were conducted with 20 purposefully selected participants from Dar es Salaam, Shinyanga, and Pwani regions. Data were coded with NVivo 12 software and analyzed …


Hpv Vaccination In Africa In The Covid-19 Era: A Cross-Sectional Survey Of Healthcare Providers' Knowledge, Training, And Recommendation Practices, Joel Fokom Domgue, Issimouha Dille, Sharon Kapambwe, Robert Yu, Freddy Gnangnon, Lameck Chinula, Gad Murenzi, Nomonde Mbatani, Mala Pande, Fatoumata Sidibe, Joseph Kamgno, Bangaly Traore, Hicham El Fazazi, Mamadou Diop, Pierre-Marie Tebeu, Mohenou Isidore Diomande, Fabrice Lecuru, Isaac Adewole, Marie Plante, Partha Basu, Jean-Marie Dangou, Sanjay Shete Jan 2024

Hpv Vaccination In Africa In The Covid-19 Era: A Cross-Sectional Survey Of Healthcare Providers' Knowledge, Training, And Recommendation Practices, Joel Fokom Domgue, Issimouha Dille, Sharon Kapambwe, Robert Yu, Freddy Gnangnon, Lameck Chinula, Gad Murenzi, Nomonde Mbatani, Mala Pande, Fatoumata Sidibe, Joseph Kamgno, Bangaly Traore, Hicham El Fazazi, Mamadou Diop, Pierre-Marie Tebeu, Mohenou Isidore Diomande, Fabrice Lecuru, Isaac Adewole, Marie Plante, Partha Basu, Jean-Marie Dangou, Sanjay Shete

Faculty, Staff and Student Publications

INTRODUCTION: Although the burden of cervical cancer in Africa is highest, HPV vaccination coverage remains alarmingly low in this region. Providers' knowledge and recommendation are key drivers of HPV vaccination uptake. Yet, evidence about providers' knowledge and recommendation practices about the HPV vaccine against a backdrop of emerging vaccine hesitancy fueled by the COVID-19 pandemic is lacking in Africa.

METHODS: A cross-sectional study was conducted in 2021-2022 among healthcare providers involved in cervical cancer prevention activities in Africa. They were invited to report prior training, the availability of the HPV vaccine in their practice, whether they recommended the HPV vaccine, …