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Articles 1231 - 1260 of 40616
Full-Text Articles in Entire DC Network
Staff Education To Improve Provider Knowledge In Addressing Sdoh-Related Barriers Affecting Medication Adherence, Andrea Latimore
Staff Education To Improve Provider Knowledge In Addressing Sdoh-Related Barriers Affecting Medication Adherence, Andrea Latimore
Walden Dissertations and Doctoral Studies
This Doctoral of Nursing Practice (DNP) project focused on improving provider knowledge in addressing social determinants of health (SDOH) that contribute to medication nonadherence. There is a gap in provider knowledge in addressing SDOH-related barriers that contributes to poor health outcomes. Increasing provider awareness of SDOH improves patient outcomes. The practice-focused question guiding this doctoral project asked whether an educational module on SDOH improved provider knowledge in addressing SDOH-related barriers to medication adherence among adult patients with chronic illnesses. The program consisted of a pretest, an educational module delivered via a PowerPoint presentation, and a posttest. A total of 20 …
Protecting ‘Punks’: The Shortcomings Of The Prison Rape Elimination Act, Rachel Goldsmith
Protecting ‘Punks’: The Shortcomings Of The Prison Rape Elimination Act, Rachel Goldsmith
Binghamton University Undergraduate Journal
Prisoner-on-prisoner sexual abuse is widespread in US male prisons, with inmates “turning each other out” by sexually assaulting each other. While the Prison Rape Elimination Act (PREA) received unanimous support in Congress in 2003, motivated by the Human Rights Watch Report “No Escape: Male Rape in Prisons,” scholars argue that the PREA fails to protect prisoners from prison rape: for example, its standards may be ineffective or criminalize consensual sex between prisoners. This essay will examine the shortcomings of the PREA, drawing on current legal scholarship, and propose solutions to enhance the law's effectiveness in protecting prisoners. The US government …
Online Decision Support For Implementing Evidence-Based Hpv Vaccination Strategies In Texas Safety-Net Pediatric Clinics: Impact On Hpv, Mcv, And Tdap Initiation, Laura C Thormaehlen, Travis A Teague, Catherine Mary Healy, Hina Azam, Aadeel Khawaja, Laura Aubree Shay, Dale S Mantey, Sally W Vernon, Lara S Savas
Online Decision Support For Implementing Evidence-Based Hpv Vaccination Strategies In Texas Safety-Net Pediatric Clinics: Impact On Hpv, Mcv, And Tdap Initiation, Laura C Thormaehlen, Travis A Teague, Catherine Mary Healy, Hina Azam, Aadeel Khawaja, Laura Aubree Shay, Dale S Mantey, Sally W Vernon, Lara S Savas
Faculty, Staff and Students Publications
Introduction: HPV vaccination rates for adolescents in the United States are below recommended levels. The Adolescent Vaccination Program (AVP) guides pediatric clinics on how to implement evidence-based strategies to increase HPV vaccination rates. These strategies comprise the adoption of (1) immunization champions, (2) provider assessment and feedback, (3) continuing education, and (4) prompts, (5) parent reminders, and (6) parent education. The AVP systems-based intervention has demonstrated increased HPV vaccination rates in large urban pediatric clinic networks. The purpose of this study was to assess the feasibility of using an online decision support tool, the AVP Implementation Tool (AVP-IT), to …
Exploring The Theoretical Foundation With Rupture And Delayed Rupture Experiments, Shi-Qing Wang, Junpeng Wang, Asal Y. Siavoshani, Cheng Liang
Exploring The Theoretical Foundation With Rupture And Delayed Rupture Experiments, Shi-Qing Wang, Junpeng Wang, Asal Y. Siavoshani, Cheng Liang
University Research
We carry out uniaxial continuous and step stretching of various cross-linked polymer networks to demonstrate how characteristics of rupture during continuous stretching and delayed rupture after step stretching can be used to probe the structure of the emergent kinetic activation theory of bond dissociation (KATBD) for elastomeric failure. Based on delayed rupture experiments, we show that the network lifetime tntw, taken as the incubation time tdel-rupt for delayed rupture, depends on temperature in an Arrhenius like manner and is exponentially sensitive to the degree of network stretching (depicted by the step-stretch ratio λss). Rupture at λb during continuous stretching for …
Ai Applications In Assessing Risk For Periodontal Disease: A Systematic Review, Grant O. Korte, Claudia M. Tellez Freitas
Ai Applications In Assessing Risk For Periodontal Disease: A Systematic Review, Grant O. Korte, Claudia M. Tellez Freitas
Annual Research Symposium
Objectives:
The goal of this systematic review is to examine the impact of using artificial intelligence (AI) to predict a patient’s risk level for periodontal disease by analyzing proven systemic health diseases linked to periodontitis. This is being done by primarily focusing on prevention and early diagnosis using machine learning programs that have been proven effective in other fields of periodontitis research.
Methods:
To conduct this study, a comprehensive literature review of journals published after 2020 was performed through four databases: PubMed, Scopus, Web of Science and Dentistry and Oral Science Source. The search was completed in adherence …
Recent Advances In The Pharmacological Properties Of Scutellarin: Mechanistic Insights And Therapeutic Potential, Hind A. Satar, Emad Yousif, Ahmed Ahmed, Muna Bufaroosha
Recent Advances In The Pharmacological Properties Of Scutellarin: Mechanistic Insights And Therapeutic Potential, Hind A. Satar, Emad Yousif, Ahmed Ahmed, Muna Bufaroosha
AUIQ Complementary Biological System
Scutellarin, a flavonoid glycoside primarily derived from Scutellaria baicalensis, has garnered increasing scientific interest for its multifaceted pharmacological properties. This review summarizes recent advances in our understanding of scutellarin's therapeutic effects, including its antioxidant, anti-inflammatory, neuroprotective, cardioprotective and anticancer activities. Emphasis is placed on elucidating its molecular mechanisms of action, such as modulation of the NF-κB, Nrf2, and PI3K/Akt pathways, and its role in regulating oxidative stress, inflammation, and apoptosis. Additionally, we discuss formulation innovations, including nanoparticle and liposomal delivery systems, aimed at overcoming scutellarin's poor oral bioavailability and enhancing therapeutic performance. Key limitations in current research …
Biomarkers In Alzheimer's Disease Clinical Trials: 2025, Amanda M. Leisgang Osse, Yadi Zhou, Jefferson W. Kinney, Andrew Hooyman, Ayan Sengupta, Jorge Fonseca, Aaron H. Burstein, Laura Nisenbaum, Howard M. Fillit, Feixiong Cheng, Jeffrey L. Cummings
Biomarkers In Alzheimer's Disease Clinical Trials: 2025, Amanda M. Leisgang Osse, Yadi Zhou, Jefferson W. Kinney, Andrew Hooyman, Ayan Sengupta, Jorge Fonseca, Aaron H. Burstein, Laura Nisenbaum, Howard M. Fillit, Feixiong Cheng, Jeffrey L. Cummings
Physical Therapy Faculty Articles and Research
Biomarkers play an important role in Alzheimer's disease (AD) clinical trials in several contexts of use, including defining trial eligibility and serving as outcome measures. Utilizing clinicaltrials.gov, a registry of clinical trials, we assessed biomarker usage across all active AD disease-targeted therapeutic (DTT) trials. Biomarkers are widely used in AD DTT trials, with 84% including a fluid, imaging, and/or digital biomarker, either as an inclusion criterion or as an outcome measure. In DTT trials, biomarkers were included in 83% of Phase 3 trials, 91% of Phase 2 trials, and 72% of Phase 1 trials. Biomarkers were used for trial inclusion …
Search Techniques In Pubmed, Kristin Kroger
Search Techniques In Pubmed, Kristin Kroger
Library Learn - Complete Video Collection
This recording provides an overview of essential PubMed search techniques to develop a structured search strategy, integrate MeSH terms with keywords, refine and manage results, access full‑text articles, and make use of key My NCBI features to streamline ongoing research.
Chemical And Structural Characterization Of Ramie-Based Epoxy Composites Reinforced With Macadamia Nut Shell Biochar, Dawit Tafesse Gebreyohannes
Chemical And Structural Characterization Of Ramie-Based Epoxy Composites Reinforced With Macadamia Nut Shell Biochar, Dawit Tafesse Gebreyohannes
Faculty, Staff and Students Publications
This study examined the effect of biochar by macadamia nut shell waste on the mechanical behaviour of ramie fibre reinforced epoxy composite. Controlled pyrolysis was used to prepare biochar at 350 °C, followed by ball milling to produce a mesoporous carbon structure with a crystallinity index of 40.5%, a crystallite size of 1.6 nm, a Brunauer–Emmett–Teller (BET) surface area of 326 m2/g and an average pore size of 3.8 nm. Fourier Transform Infrared Spectroscopy (FTIR) and X-ray diffraction (XRD) analyses confirmed partial graphitization and the presence of oxygen-containing functional groups, while surface roughness analysis (Ra = 0.2382 µm, Rq = …
Engineering Chimeric Antigen Receptor Cd4 T Cells For Alzheimer's Disease, Pavle Boskovic, Rotem Shalita, Wenqing Gao, Hailey Vernon, Yu Lin Deng, Marco Colonna, Robbie G Majzner, Ido Amit, Jonathan Kipnis
Engineering Chimeric Antigen Receptor Cd4 T Cells For Alzheimer's Disease, Pavle Boskovic, Rotem Shalita, Wenqing Gao, Hailey Vernon, Yu Lin Deng, Marco Colonna, Robbie G Majzner, Ido Amit, Jonathan Kipnis
2020-Current year OA Pubs
Alzheimer's disease (AD) is the prevailing cause of age-associated dementia worldwide. Current standard of care relies on antibody-based immunotherapy. However, antibody-based approaches carry risks for patients, and their effects on cognition are marginal. Increasing evidence suggests that T cells contribute to AD onset and progression. Unlike the cytotoxic effects of CD8
Larval Zebrafish Minimize Energy Consumption During Hunting Via Adaptive Movement Selection, Thomas Darveniza, Robert Wong, Shuyu I Zhu, Zac Pujic, Biao Sun, Matthew Levendosky, Ramesh Agarwal, Michael H Mccullough, Geoffrey J Goodhill
Larval Zebrafish Minimize Energy Consumption During Hunting Via Adaptive Movement Selection, Thomas Darveniza, Robert Wong, Shuyu I Zhu, Zac Pujic, Biao Sun, Matthew Levendosky, Ramesh Agarwal, Michael H Mccullough, Geoffrey J Goodhill
2020-Current year OA Pubs
Animals must balance behavioral goals with the energetic costs of movement. How such trade-offs are implemented algorithmically during natural behavior, and how they adapt to changing energetic constraints, remains poorly understood. Here we show that larval zebrafish adjust their motor strategies during prey hunting to minimize energy expenditure. Using high-speed video tracking and 3D computational fluid dynamics simulations, we quantified the energy costs (in Joules) of different movement types across three developmental stages. While the structure of discrete movement types ("bouts") remained stable with age, their selection probabilities changed depending on their energetic cost, such that more expensive bouts were …
Txa In Dentistry, Valeria Coronilla, Jaime Cabrera-Pardo
Txa In Dentistry, Valeria Coronilla, Jaime Cabrera-Pardo
Annual Research Symposium
No abstract provided.
Strspy2.0: Unlocking The Potential Of Long Reads For Forensic Dna Profiling, Bupe Kapema, Nicole R Phillips, Fritz J Sedlazeck, Roxanne R Zascavage
Strspy2.0: Unlocking The Potential Of Long Reads For Forensic Dna Profiling, Bupe Kapema, Nicole R Phillips, Fritz J Sedlazeck, Roxanne R Zascavage
Faculty, Staff and Students Publications
Forensic human identification relies on length-based differences in short tandem repeats (STRs) across autosomal and Y chromosomes, which require separate reactions and provide limited resolution. While next-generation sequencing offers greater discriminatory power, most platforms are expensive and restricted to traditional lab settings. Nanopore sequencing has the potential to change this with the real-time, portable MinION sequencer. However, forensic-specific tools that generate STR profiles compatible with established length-based databases are lacking. To address this, we developed STRspy2.0, which simultaneously profiles autosomal and Y-STRs using nanopore reads. STRspy2.0 produced accurate profiles for 54 multiplexed control libraries and 41 mock casework samples (blood, …
Emotional Intelligence And Problem-Solving Correlations And Impact On Employability: A Case Study From The Uae, Ganka Ivanova, Rakan Alhrhasheh
Emotional Intelligence And Problem-Solving Correlations And Impact On Employability: A Case Study From The Uae, Ganka Ivanova, Rakan Alhrhasheh
All Works
In this study, we aim to address questions about how UAE Leadership Development Plans and Employability connect with current students in UAE classrooms by evaluating the correlation between the employability of UAE university students and their emotional intelligence (EI) and problem-solving skills. Moreover, we cover what must be considered in the curricula of UAE Universities to prepare future leaders to lead the workforce. To that end, we employed an employability test developed by AQR International UK and collected data from 310 undergraduate students aged 17 to 55. Both EI and problem-solving skills were strongly positively correlated with employability (p < .001). Even though male participants scored higher than female participants for EI and problem-solving skills, analysis of variance revealed nonsignificant gender differences (p > .05 …
Competencies And Preparation For Addressing Poverty In Counselor Education: A Q Methodological Study, Seneka Rachel Gainer
Competencies And Preparation For Addressing Poverty In Counselor Education: A Q Methodological Study, Seneka Rachel Gainer
Journal of Counselor Preparation and Supervision
This study explored the competencies needed to prepare counselors to address the systemic and relational impacts of poverty within counselor education. Using Q methodology, expert participants identified critical knowledge, skills, and awareness factors required for effective practice. Two distinct factors emerged: (1) the centrality of relational competencies such as empathy, cultural humility, and trust-building, and (2) the necessity for curriculum-wide integration of poverty-specific training and systemic advocacy. Findings highlight the need for counselor education programs to embed poverty-related competencies across curricula, foster interdisciplinary collaboration, and develop experiential and advocacy-based training models. Implications for counselor education, accreditation standards, and professional development …
The Feminist Impostor Phenomenon Approach (Fipa): A Feminist Approach To Addressing Impostor Phenomenon In Novice Counselors, Isabel Springer, Kelly Emelianchik-Key
The Feminist Impostor Phenomenon Approach (Fipa): A Feminist Approach To Addressing Impostor Phenomenon In Novice Counselors, Isabel Springer, Kelly Emelianchik-Key
Journal of Counselor Preparation and Supervision
Impostor Phenomenon (IP) is known to affect new professionals in health professions, yet there is little to no academic literature available on how it affects early career counselors and how it can be addressed. Novice counselors (NC) frequently experience extreme anxiety and feelings of fraudulence around their professional performance. Feminist mentorship and interventions can help alleviate IP and foster self-efficacy and confidence in new counseling professionals. The Feminist Impostor Phenomenon Approach (FIPA) consists of a three-hour workshop educating participants through a feminist lens about IP and relevant coping strategies, and subsequent weekly consciousness-raising groups where coping strategies are reinforced, and …
Artificial Intelligence Literacy In Counselor Education: The Developmental Ai Literacy Framework, Leo Gonzalez Jr.
Artificial Intelligence Literacy In Counselor Education: The Developmental Ai Literacy Framework, Leo Gonzalez Jr.
Journal of Counselor Preparation and Supervision
Artificial intelligence (AI) is transforming counselor education, yet frameworks for preparing counselors-in-training (CITs) to use AI remain limited. This article introduces the developmental AI literacy framework (DALF), a conceptual model integrating developmental theory, professional identity formation, and AI literacy. The DALF reframes AI literacy as a developmental competency comprising intentional AI use, critical evaluation, ethical engagement, and awareness of professional identity. The framework outlines three stages, including foundational awareness, reflective application, and integrated professionalization, that parallel CITs’ growth from dependence to autonomy. Pedagogical, developmental, and research implications are provided to guide ethical and reflective AI integration in counselor education.
Feasibility And Form Factor Validation Of Reflective Shoulder-Mounted Pulse Oximeter In Patients With Suspected Sleep Apnea, Katie N. Kanter, Aaron Wang, David Gordon, Adina Singer, Jacob S. Brenner, Indira Gurubhagavatula, Anush Lingamoorthy, Olumuyiwa Oni, Cameron M. Baston
Feasibility And Form Factor Validation Of Reflective Shoulder-Mounted Pulse Oximeter In Patients With Suspected Sleep Apnea, Katie N. Kanter, Aaron Wang, David Gordon, Adina Singer, Jacob S. Brenner, Indira Gurubhagavatula, Anush Lingamoorthy, Olumuyiwa Oni, Cameron M. Baston
SKMC Student Presentations and Publications
The shoulder may be an effective central site for continuous oxygen saturation (SpO2) monitoring but studies of shoulder-mounted pulse oximetry technology are limited. We hypothesized that an alternative location would be similar in function and user acceptance to a standard FDA-cleared finger-based pulse oximeter. We conducted a quantitative and descriptive pilot study of two prototype biosensor designs in patients with clinical suspicion of hypoxic episodes at an outpatient sleep center. Participants wore two prototype biosensors-the primary a shoulder-mounted adhesive and the secondary a combination ring-bracelet-in addition to a control FDA-approved finger-based pulse oximeter. We assessed the comfort of the devices …
P-15 Peptide Enhanced Bone Graft In Transforaminal Lumbar Interbody Fusion: A Randomized, Controlled, Investigational Device Exemption Study Demonstrating Improved Composite Clinical Success, James Harrop, John E. O'Toole, Michael P. Steinmetz, Rick C. Sasso, Christopher D. Chaput, K. Brandon Strenge, Greg Maislin, Jeffrey P. Mullin, Thomas B. Freeman, Anthony Guanciale, Howard Lantner, Michael E. Janssen, David G. Schwartz, John M. Small, Wellington K. Hsu, Paul M. Arnold
P-15 Peptide Enhanced Bone Graft In Transforaminal Lumbar Interbody Fusion: A Randomized, Controlled, Investigational Device Exemption Study Demonstrating Improved Composite Clinical Success, James Harrop, John E. O'Toole, Michael P. Steinmetz, Rick C. Sasso, Christopher D. Chaput, K. Brandon Strenge, Greg Maislin, Jeffrey P. Mullin, Thomas B. Freeman, Anthony Guanciale, Howard Lantner, Michael E. Janssen, David G. Schwartz, John M. Small, Wellington K. Hsu, Paul M. Arnold
Department of Orthopaedic Surgery Faculty Papers
STUDY DESIGN: Prospective, multicenter, single-blind, randomized, controlled pivotal study.
OBJECTIVE: To evaluate whether P-15L (PearlMatrix P-15 Peptide Enhanced Bone Graft) is noninferior in effectiveness to local autograft when applied in single-level instrumented transforaminal lumbar interbody fusion (TLIF).
SUMMARY OF BACKGROUND DATA: P-15L, an FDA-designated Breakthrough Drug-Device, is a composite drug-device combination bone graft containing P-15, a 15-amino acid polypeptide, which enhances cell binding, proliferation, and differentiation, resulting in bone formation.
MATERIALS AND METHODS: Skeletally mature patients, aged 22 to 80 years, with degenerative disc disease (DDD) were randomized 1:1 to P-15L (investigational) or to the local autograft (control) during single-level …
Hubungan Marketing Mix Dan Hospital Brand Image Dengan Minat Kunjungan Ulang Pasien Di Rsi Sultan Agung Banjarbaru, Fitriani Fitriani, M. Noor Ifansyah, Zubaidah Zubaidah
Hubungan Marketing Mix Dan Hospital Brand Image Dengan Minat Kunjungan Ulang Pasien Di Rsi Sultan Agung Banjarbaru, Fitriani Fitriani, M. Noor Ifansyah, Zubaidah Zubaidah
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
Hospitals are required to provide high-quality services to increase patient visits. Over the past six months, RSI Sultan Agung Banjarbaru has experienced a decline in the number of patient visits. This study aimed to analyze the relationship between the marketing mix and hospital brand image with revisit intention. The study employed a correlational analytic design, involving an outpatient population of 107,146 patients. A total of 100 respondents were selected using purposive sampling, and data were collected through questionnaires. Data analysis was conducted using the Spearman’s Rho test. The results showed that the marketing mix and hospital brand image variables were …
Prephiral Bacterial Infectious Agent Triggers Neuroinflammatory Responses And Neurobehavioral Impairment In Wild-Type Mice, Hadeer Atalah
Prephiral Bacterial Infectious Agent Triggers Neuroinflammatory Responses And Neurobehavioral Impairment In Wild-Type Mice, Hadeer Atalah
Theses and Dissertations
Neurodegenerative diseases, including Alzheimer's and Parkinson's, present an increasing global challenge, with chronic neuroinflammation identified as a principal factor alongside genetic, environmental, and infectious influences (Boyd et al., 2022). Epidemiological data associate bacterial infections with a 40% heightened risk of Parkinson's disease; however, the mechanisms—especially the direct connection between peripheral sepsis and the silent onset of central nervous system pathology absent acute meningitis—are inadequately investigated (Smeyne et al., 2021), particularly concerning common pathogens like Klebsiella pneumoniae in high-burden areas such as Egyptian ICUs, where it constitutes 30% of cases (Alkompoz et al., 2023). This study filled the gap by creating …
Investigating Tau Pathology In The Retina And Anterior Segment Structures Of The Eye In A 3-Nitropropionic Acid–Induced Tauopathy Mouse Model, Mohamed Sayed Ahmed Abdel-Kader Qasem
Investigating Tau Pathology In The Retina And Anterior Segment Structures Of The Eye In A 3-Nitropropionic Acid–Induced Tauopathy Mouse Model, Mohamed Sayed Ahmed Abdel-Kader Qasem
Theses and Dissertations
Background and Objectives: Alzheimer's disease, the most prevalent neurodegenerative disorder in older adults, is characterized by accumulation of hyperphosphorylated tau and amyloid-beta (Aβ) plaques in the central nervous system. Given the retina's shared embryological origin with the brain, its direct neural connectivity via the optic nerve, and similarities in vasculature and age-related degeneration patterns, retinal pathology may serve as an early, non-invasive biomarker for Alzheimer's disease. This study employed 3-nitropropionic acid (3NP) as a pathway-specific tauopathy model driven by mitochondrial dysfunction. The study particularly aimed to investigate whether retinal and corneal tau pathology reflects underlying tau-related neurodegeneration triggered by …
Global Public Health Feasibility: Digital Dentistry In Geriatric Population, Merna Amr Saleh
Global Public Health Feasibility: Digital Dentistry In Geriatric Population, Merna Amr Saleh
Theses and Dissertations
Oral health is a critical yet often overlooked determinant of well-being among older adults in Egypt, where mobility limitations, geographic barriers, and low awareness of preventive practices exacerbate dental disparities. DentalPal, a teledentistry-based mobile application, was developed to provide older adults with remote dental consultations, oral hygiene advice, and triage guidance. The platform enables users to submit oral photographs or radiographs for assessment, seek second opinions, and initiate follow-up chats directly with the healthcare provider. This flexible design allows users to access dental consultations on demand while ensuring continuity of care The question that guided this study was how older …
Facebook Interaction As A Potential Marker Of Cognitive Decline: Pilot Study, Esraa M. Qansuwa
Facebook Interaction As A Potential Marker Of Cognitive Decline: Pilot Study, Esraa M. Qansuwa
Theses and Dissertations
One of the critical challenges in brain disorder research is the early identification of individuals with mild cognitive impairment (MCI) who may later develop Alzheimer’s disease (AD) or other dementias. MCI in older adults is frequently associated with diminished social engagement and observable behavioral changes. With the rapid expansion of social media platforms and advances in Machine Learning (ML), digital traces from online activity present a novel and scalable avenue for mental health screening. In particular, predictive ML approaches have demonstrated strong potential in building reliable classifiers for early detection of neurocognitive decline. This study introduces an innovative framework that …
Perceptions Of Healthcare Access Barriers Among Eritrean, Sudanese, And Somali Refugees And Asylum Seekers In Cairo., Ayan Musa Mohamed
Perceptions Of Healthcare Access Barriers Among Eritrean, Sudanese, And Somali Refugees And Asylum Seekers In Cairo., Ayan Musa Mohamed
Theses and Dissertations
As the world witnesses an increase in different displacements of individuals for various reasons, ranging from wars, civil conflicts, human rights violations, and natural disasters, refugees and asylum seekers, who are among those forcibly displaced, continue to face challenges in access to health care services in host countries. The topic of barriers to health care has been widely researched, with a large body of literature on refugees' interactions with health care systems. However, there is limited literature on the perceptions of Eritrean, Sudanese, and Somali refugees and asylum seekers' experience with healthcare access in host countries. Therefore, this thesis aims …
Uncovering Potential Therapeutic Targets For Spinal Cord Injury; Insights From Single-Cell And Cross-Species Transcriptomics, Sara Samy Abouzekry
Uncovering Potential Therapeutic Targets For Spinal Cord Injury; Insights From Single-Cell And Cross-Species Transcriptomics, Sara Samy Abouzekry
Theses and Dissertations
Central nervous system (CNS) injury remains a devastating healthcare problem. Despite years of research, it remains almost impossible to achieve meaningful functional repair following traumatic brain injury (TBI) and spinal cord injury (SCI). Spinal cord injury (SCI), a highly devastating subset of CNS trauma, is considered a challenge due to the extremely limited regenerative capacity of the nervous system in adult mammals. In contrast, certain species display remarkable repair abilities followed by moderate regenerative ability in neonatal mammals, indicating that regeneration is shaped by the evolutionary context as well as the developmental age.
To uncover the core molecular mediators of …
Optimizing Electrode Placement And Information Capacity For Local Field Potentials In Cortex, Jace A Willis, Christopher E Wright, Ruoqian Zhu, Yilan Ruan, Joshua Stallings, Takfarinas Medani, Arjun Ramakrishnan, Charles E Schroeder, Anand A Joshi, Nitin Tandon, Richard M Leahy, John C Mosher, John P Seymour
Optimizing Electrode Placement And Information Capacity For Local Field Potentials In Cortex, Jace A Willis, Christopher E Wright, Ruoqian Zhu, Yilan Ruan, Joshua Stallings, Takfarinas Medani, Arjun Ramakrishnan, Charles E Schroeder, Anand A Joshi, Nitin Tandon, Richard M Leahy, John C Mosher, John P Seymour
Faculty, Staff and Student Publications
Recent neurosurgery advancements include improved stereotactic targeting and increased density and specificity of electrophysiological evaluation. This study introduces a subject-specific, in silico modeling tool for optimizing electrode placement and maximizing coverage with a variety of devices. The basis for optimization is the Shannon-Hartley information capacity of field potentials derived from dipolar sources. The approach integrates subject-specific MRI data with finite element modeling (FEM) used to simulate the sensitivity of subdural and intracortical devices. Sensitivity maps, or lead fields, from these models enable the comparison of different electrode placements, contact sizes, contact configurations, and substrate properties, which are often overlooked factors. …
Pediatric Inflammatory Bowel Disease Tissue Classification From Pathology Slide Images: Detecting Phenotypes Using Computer Vision, Chloe Martin-King, Ali Nael, Louis Ehwerhemuepha, Blake Calvo, Quinn Gates, Jamie Janchoi, Elisa Ornelas, Melissa Perez, Andrea Venderby, John Miklavcic, Peter Chang, Aaron Sassoon, Brian Rubio, Ghislaine Barrigan, Kenneth Grant
Pediatric Inflammatory Bowel Disease Tissue Classification From Pathology Slide Images: Detecting Phenotypes Using Computer Vision, Chloe Martin-King, Ali Nael, Louis Ehwerhemuepha, Blake Calvo, Quinn Gates, Jamie Janchoi, Elisa Ornelas, Melissa Perez, Andrea Venderby, John Miklavcic, Peter Chang, Aaron Sassoon, Brian Rubio, Ghislaine Barrigan, Kenneth Grant
Food Science Faculty Articles and Research
Background and Aims
With the advent of computer vision algorithms, we hypothesize that histopathology images from endoscopic biopsies may be utilized for automated classification of histologic phenotypes, thus guiding Crohn’s disease and ulcerative colitis diagnosis and treatment. The aim of our study is to assess whether artificial intelligence can be used to improve pediatric inflammatory bowel disease outcomes by aiding pathologists with accurate detection of abnormal tissue sections.Methods
Three two-dimensional (2D) convolutional neural networks with multiple instance learning were developed to classify histopathology tissue sections as normal vs abnormal and as containing active inflammation and/or chronic changes/architectural distortion.Results …
Penguatan Pengendalian Persediaan Obat Melalui Integrasi Abc-Ven, Eoq, Dan Rop Di Rumah Sakit Rujukan Nasional, Rasendah Rasendah, Helen Andriani, Dendhi Bagus Andriyanto
Penguatan Pengendalian Persediaan Obat Melalui Integrasi Abc-Ven, Eoq, Dan Rop Di Rumah Sakit Rujukan Nasional, Rasendah Rasendah, Helen Andriani, Dendhi Bagus Andriyanto
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
Drug inventory control is a critical component of pharmaceutical management in referral hospitals with high service complexity. This study aimed to evaluate pharmaceutical inventory control performance at the Pharmacy Installation of RSUP Persahabatan and to formulate improvement strategies using an Operational Research approach. A mixed-methods design with a sequential explanatory approach was applied. Quantitative analysis was conducted on 2,291 drug items recorded in the inventory system during October 2025 using ABC-VEN classification to identify priority medicines, followed by calculations of Economic Order Quantity (EOQ) and Reorder Point (ROP). Qualitative data were obtained through in-depth interviews with key informants to strengthen …
Finding Research Datasets And Evaluating Data Quality, Ibis Anette Moreno-Lozano Phd.
Finding Research Datasets And Evaluating Data Quality, Ibis Anette Moreno-Lozano Phd.
Day Family Research Lab Workshop Series
No abstract provided.