Digital Commons Network^™

What Factors Influence Health Professions Trainees’ Preferences For Employment In Rural Appalachia? A Qualitative Study To Inform The Design Of A Discrete Choice Experiment, Chris Gillette, Jan Ostermann Ph.D., Aylin A. Aguillar, Sarah O'Neal, Chris Everett, Dawn Caviness, Esita Patel, Laiton Steele, Dawn Goel, Quazi Minhaz Tabassum

Faculty Publications

Optimizing the geographic allocation of health care providers has the potential to improve health care access and health outcomes for rural populations. To inform the design of a discrete choice experiment (DCE) survey to elicit health professions trainees' preferences for rural practice, this formative research aimed to: (1) elicit factors that influence job selection among health profession trainees, including medical residents physician assistant (PA) and nurse practitioner (NP) students, (2) identify how these trainees evaluate trade-offs for rural job placement and (3) inform attribute selection for inclusion into a future DCE to identify health professions trainees’ preferences for rural practice. …

Recent Progress In Nanogel Technology: From Molecular Design To Biomedical Applications, Fatima Raed Al-Ahmed, Mohammed Sabar Al-Lami

Maaen Journal for Medical Sciences

Nanogels, a hydrophilic polymer network at the nanoscale, combine the structural flexibility of hydrogels with the dynamic behavior of nanoparticles, offering unprecedented control over drug loading and release. Their large surface area, tunable porosity, high water content, biocompatibility, and stimuli-responsive behavior enable transport across biological barriers. This review critically examines nanogels’ unique properties, classifications, diverse methods of preparation, drug release mechanisms, characterization techniques, and various applications in therapeutic areas, such as cancer therapy, wound healing, transdermal and ocular drug delivery, and theranostics. Highlights are shed on nanogels’ potential to target specific sites, both by functionalization and stimuli-responsive behavior, therefore improving …

Evaluation Of Nurses' Leadership Self-Efficacy In Belize, Ruth Rosalee Reina Jones

Walden Dissertations and Doctoral Studies

Nursing leadership in Belize is lacking but crucial to the well-being of patients, families, and the healthcare team. The purpose of this non-experimental, descriptive, comparative study was to a) determine the difference in leadership self-efficacy for current nurse leaders with three years or less of leadership experience compared to current nurse leaders with more than three years of leadership experience in Belize, and b) examine the differences in leadership self-efficacy between nurses in a leadership position and nurses not in a leadership position in Belize. The theories supporting the study were Burns’ transformational leadership theory and leadership self-efficacy, based on …

Investigation Of Molecular Footprints In Ultra-High Diluted Homoeopathic Solutions Of Arnica Montana And Rhus Toxicodendron Through Combined Infrared And Impedance Spectroscopy, Sharbadeb Kundu, Usha Rani Dash, Chirasree Roychaudhuri, Aindrila Roy, Sanatan Chattopadhyay, Rathin Chakravarty, Debadatta Nayak, Subhash Kaushik, Amit Roy Chowdhury, Ananya Barui, Subhadip Chakraborty

Indian Journal of Research in Homoeopathy

Background: The study of ultra-high diluted (UHD) solutions is a compelling and controversial domain in modern science. Despite numerous investigations and hypotheses, there is a lack of rigorous, reproducible empirical evidence supporting the existence of molecular footprints beyond the Avogadro's limit. Objective: This study conducted a detailed investigation of the molecular and electrical properties, focusing on hydrogen bonding and impedance to understand the fundamental nature of UHD solutions. Materials and methods: Combined impedance and infrared spectroscopic investigations were performed to probe the structural behaviour of relevant water networks at the molecular level of UHD alcoholic extract of Arnica montana (AM) …

Panic Disorder Treated With Individualised Homoeopathic Medicines: A Case Series, Hima Bindu Ponnam, Gr Kiranmayee Rompicherla

Indian Journal of Research in Homoeopathy

Introduction: Panic disorder is one category of generalised anxiety disorder that is commonly reported in a majority of the outpatient departments of primary care hospitals, especially in the COVID-19 post-pandemic era. Although its prevalence is lower compared to other anxiety disorders, panic disorder remains a serious concern, as it often leads to cardiorespiratory emergencies; therefore, prompt recognition and timely management are crucial. Since the first-line pharmacological interventions of modern medicine are expensive and associated with certain undesirable side effects, the homoeopathic system of medicine appears to be a safer and more economical alternative in such cases. Keeping this in view, …

Incidence Of Autoimmune Diseases In Children With Atopy Treated With Dupilumab, Stanislaw J Gabryszewski, Kathryn Hirabayashi, Morgan Botdorf, Mitchell Maltenfort, Christopher B Forrest, Theresa W Guilbert, Madeline Schutt, Hiroki Morizono, Gerardo Vazquez Garcia, Anna Cristina Garza-Mayers, Joseph Demetrius Hernandez, Sara Anvari, Suchitra Rao, Jonathan M Spergel

Faculty, Staff and Students Publications

Background: The type 2 inflammation-blocking agent dupilumab has gained traction as an effective treatment of multiple atopic diseases. New-onset autoimmune manifestations have been infrequently reported in dupilumab-treated atopic patients, primarily among adults. Autoimmune outcomes in atopic children on dupilumab are less clear.

Objective: We aimed to determine if dupilumab treatment of atopic children is associated with increased autoimmune or autoinflammatory disease diagnosis risk.

Methods: Using a multi-institutional electronic health record database composed of 10 PEDSnet academic health systems, we performed a retrospective cohort study of children aged 6-17 with atopy (ie, moderate-to-severe atopic dermatitis and/or persistent asthma, as defined by …

Multi-Modal Tensor Fusion For Alzheimer’S Disease Recognition, Mason Li, Tiffany Le, Jiajing Huang, Yuxin Wen

Engineering Faculty Articles and Research

Accurate and early diagnosis of Alzheimer’s disease (AD) is critical for effective intervention, disease monitoring, and patient care. Traditional diagnostic approaches rely on a single modality, such as clinical assessments, neuroimaging, or genetic markers, which may fail to capture the complex, multifaceted nature of AD. Multimodal learning has therefore been explored to integrate complementary information across data sources. However, conventional fusion strategies, including early feature concatenation and late decision-level fusion, often model modalities independently and fail to capture high-order cross-modal interactions. To address these limitations, we propose a multimodal tensor fusion network (MTFN) that integrates heterogeneous data sources, including visual …

Spatial Narrative Beyond The Proscenium: Set Design As A Tool For Wellness, Christina Griffey

LSU Master's Theses

Inspired by a health crisis that led to spending time in medical settings, this thesis examines how our surroundings impact our well-being. By developing a framework that explores the topics of storytelling, space, place, theatre, and expanded scenography, I propose that set design can be used as a tool for wellness. I explore several disciplines through the lens of set design and highlight the disciplines, professionals, and designers that are contributing to the creation of therapeutic environments using scenographic practices.

The Psychology Of Offensive And Defensive Intergroup Violence: Preregistered Insights From 58 Countries, Jonas R. Kunst, Tomasz Besta, Michał Jaśkiewicz, Et Al, Lauren E. Duncan

Psychology: Faculty Publications

Historically, intergroup violence has been motivated by both offensive and defensive goals, often blending narratives of protection with ambitions of domination. In a preregistered study spanning 58 countries, we show that defensive and offensive extremist intentions are positively correlated yet psychologically distinct, relating differently to individual and societal factors. Defensive extremist intentions were far more common and primarily linked to narcissism and Machiavellianism, whereas offensive extremist intentions were primarily associated with social dominance orientation and religious fundamentalism, were lower in more democratic and developed societies, and higher in those experiencing violence and conflict. This global evidence suggests that violent extremist …

“For Us, Drones Mean Health”: How Medical Drone Delivery Affects Healthcare Outcomes, Accessibility, And Trust In Remote Regions Of Madagascar, Brianne O'Sullivan, Christallin Lydovick Rakotoasy, Lorie Donelle Phd, Rn, Fcan, Nicole Haggerty, Elysée Nouvet

Faculty Publications

Medical drone delivery (MDD), defined as the use of uncrewed aerial vehicles to transport medical products, is an emerging technological innovation responding to persistent health supply chain challenges in rural and low-resource settings. Within sub-Saharan Africa, MDD systems have demonstrated large-scale success in improving key health outcomes, health supply chain efficiency, and reductions in medical product stockouts and wastage. However, the existing evidence base on the effectiveness of this technology is dominated by quantitative, performance-based evaluations, with limited emphasis on the community-driven mechanisms that shape such outcomes. Drawing on original qualitative research, this article presents a qualitative secondary analysis (QSA) …

Drug Procurement Methods And Challenges In Asian Low And Lower-Middle-Income Countries: A Systematic Review, Ferina Septiani Damanik, Anna Wahyuni Widayanti, Muhammad Qowiyul Amin

The Thai Journal of Pharmaceutical Sciences

Background: Pharmaceutical procurement plays a pivotal role in healthcare within Asian low and lower-middle-income countries (LLMICs), ensuring accessibility to essential, cost-effective, and high-quality medicines. Tailored approaches are imperative due to specific challenges inherent in these countries.
Objectives: This review examines several drug procurement systems in Asian countries with LLMICs while identifying and evaluating any potential challenges that might arise within the systems.
Materials and Methods: This review using the preferred reporting items for systematic reviews and meta-analyses guidelines and three search engines (PubMed, Science Direct, and Research Gate) employing Boolean search terms. The search focuses on drug procurement, medicine procurement, …

Efficacy And Safety Of Stem Cell-Based Interventions For Burn Wound Healing: A Systematic Review And Meta-Analysis Of Pre-Clinical And Early Clinical Evidence, Prayuth Poowaruttanawiwit, Patsanan Kulla, Naveeya Pakpoomkamonlert

The Thai Journal of Pharmaceutical Sciences

Background: Burn injuries remain a major therapeutic challenge, with conventional treatments often failing to achieve complete functional skin regeneration. Stem cell-based interventions, including mesenchymal stem cells (MSCs) and exosome derivatives, have demonstrated regenerative and immunomodulatory potential, yet their translation to clinical practice remains limited.
Objectives: To systematically evaluate the efficacy and safety of stem cell-based therapies for burn wound healing across pre-clinical and clinical studies.
Materials and Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines, four databases (PubMed, Embase, Scopus, and Cochrane) were searched through April 2025. Eligible studies included randomized controlled trials and controlled pre-clinical …

Bacteriophage Therapy For Antibiotic-Resistant Infections, Shiva Pariyar

Best Integrated Writing

Pariyar examines bacteriophage therapy as a promising alternative to antibiotics for treating multidrug-resistant infections, highlighting its targeted mechanism, ability to disrupt biofilms, and synergy with antibiotics. While challenges such as regulation, immune response, and limited clinical trials remain, the study argues that advances in biotechnology and global collaboration position phage therapy as a future cornerstone in combating antimicrobial resistance.

Whole-Genome Crispr Screening Identifies Genetic Modifiers Of Stem Cell-Derived Islet Transplantation, Marlie M Maestas, Kameron Bradley, Mira Shunkarova, Noyonika Mukherjee, Matthew Ishahak, James Lu, Jeffrey R Millman

2020-Current year OA Pubs

INTRODUCTION: Genetically engineering human pluripotent stem cell (hPSC)-derived islets is a promising strategy for improving transplantation for diabetes cell therapy; however, genetic perturbations that modulate transplantation outcomes have yet to be systematically explored.

METHODS: To identify potential targets, we performed an unbiased whole-genome CRISPR-activation screen in transplanted stem cell-derived islets (SC-islets). Specifically, we created a stem cell line with CRISPR-activation components (HUES8-VPR) and then transduced these stem cells with a lentiviral guide RNA library targeting the whole human genome. Following transduction, the stem cells were differentiated into SC-islets, which were subsequently transplanted into NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (NSG) immunodeficient mice. After transplantation, SC-islets …

Γδ T Cells At The Interface Of Innate And Adaptive Immunity In Cancer, Arnau Solé Casaramona, Martin F Bachmann, Eva Sevick-Muraca, Mona O Mohsen

The Brown Foundation: Institute of Molecular Medicine

γδ T cells are unconventional lymphocytes that bridge innate and adaptive immunity by combining recognition of stress-induced ligands independently of classical major histocompatibility complex molecules with the capacity to undergo clonal expansion and long-term adaptation. Their unusual ability to detect malignant transformation using semi-invariant T-cell receptors, butyrophilin recognition and natural killer-like receptors positions them as powerful effector cells in tumors that evade classical immune escape mechanisms. Furthermore, distinct γδ subsets have distinct phenotyping and specific tissue-residencies, which could be leveraged to modulate immunological responses. We evaluate engineered therapies and different experimental platforms for studying γδ T cell biology. We conclude …

Assessment Of Early Breast Cancer Response To Chemotherapy With Ultrasound Radiomics, Swapnil Dolui, Basak Dogan, Corinne Wessner, Jessica Porembka, Priscilla Machado, Bersu Ozcan, Nisha Unni, Maysa Abu-Khalaf, Flemming Forsberg, Kibo Nam, Kenneth Hoyt

Department of Medical Oncology Faculty Papers

Objective: This prospective study investigated the use of H-scan ultrasound (US) imaging as a novel component of a multiparametric radiomic analysis framework for characterizing human breast cancer response to neoadjuvant chemotherapy (NAC) before and early after treatment initiation. Methods: Thirty breast cancer patients scheduled for NAC were scanned using a clinical US system (Logiq E9, GE HealthCare) equipped with a 9L-D linear array transducer. Radiofrequency (RF) data was obtained at baseline (pre-NAC) and after 10% and 30% of the complete dose of chemotherapy. The RF data was analyzed by a bank of 256 frequency-shifted bandpass filters to form H-scan US …

Aquifer Characteristics And Groundwater Flow Modeling For Sustainable Water Resources Development And Planning Using Modflow Software In India, Ravi Sharma

AUIQ Complementary Biological System

MODFLOW is one of the most commonly used numerical models for simulating groundwater flow. Its structured data design and compatibility with GIS tools make it suitable for groundwater assessment and planning. Groundwater forms an important part of the hydrological cycle and occurs within the pore spaces of sedimentary rocks or within fractures in hard rock terrains. Although its distribution beneath the surface is not always uniform or predictable, it is still considered one of the cleanest, most accessible, and quickly available freshwater sources. Numerical groundwater models help convert complex subsurface processes into simplified relationships that describe flow behavior. Even though …

Health Effects Of Cadmium And Manganese Exposure On Luteinizing Hormone Levels: A Pilot Study Of Female Infertility, Shatha F. Alhous, Anees A. Al-Hamzawi, Murtadha Sh. Aswood

Al-Bahir

Female infertility occurs for many reasons, some unknown. Exposure to heavy metals is a risk factor that negatively impacts on female reproductive system. Therefore, this study aimed to evaluate the effect of cadmium Cd and manganese Mn on luteinizing hormone LH levels for females’ infertility. This study included a healthy group (n = 20), primary infertile females (n = 40), and secondary infertile females (n = 20) collected from Al-Zahraa hospital in Najaf center, Iraq. The Atomic Absorption Spectroscopy (AAS) was used to measure the cadmium and manganese concentrations and LH levels were measured by a Maglumi 800 from Snibe …

Chatgpt Versus Uptodate In Preclinical Medical Education: Cross-Sectional Analysis Using Term Frequency-Inverse Document Frequency Cosine Similarity, Shankar S. Thiru, Nicholas E. Aksu, Matthew Chiang, Daniel O. Gallagher, Mary Furlong, Elizabeth R. Prevou, Akhil Jay Khanna

Rothman Institute Papers

BACKGROUND: Generative artificial intelligence tools such as ChatGPT are increasingly used by medical students for self-directed learning. Although these models demonstrate linguistic fluency, their reliability as supplementary resources for preclinical education remains uncertain. In particular, comparisons with evidence-based references such as UpToDate are lacking.

OBJECTIVE: This study evaluated the similarity between responses generated by ChatGPT (with GPT-4o mini) and those from UpToDate to preclinical medical education questions to assess ChatGPT's potential as an adjunctive learning tool.

METHODS: We conducted a cross-sectional comparison study using 150 first-order questions derived from a preclinical question bank at a single allopathic institution under the …

Receptor-Mediated Drug Delivery: Redefining Targeted Drug Conjugates In Oncology, Keon Niles Jafari, Charlene Chai, Shelby Kim, Kamaljit Kaur

Pharmacy Faculty Articles and Research

Targeted drug delivery (TDD), specifically through targeting ligand–drug conjugates, has reshaped oncology by enabling selective delivery of cytotoxic payloads to cancer cells while minimizing uptake by normal tissues. A key approach relies on exploiting overexpressed cell surface receptors (CSRs) to enable selective uptake of drug conjugates via receptor-mediated endocytosis. This review delineates four clinically validated CSRs (HER2, Trop-2, Nectin-4, and SSTR2) with several FDA-approved drug conjugates. Furthermore, emerging CSRs (EGFR, DLL3, and keratin 1) that may support next-generation TDD platforms for cancer treatment are also highlighted. We discuss how CSR type, density on cancer cells, and its mechanism of endocytosis, …

Self-Clustering Of Three Cbx2 Molecules Drives Prc2 To Promote Facultative Heterochromatinization Of Polycomb Target Genes, Steven Ingersoll, Abby Trouth, J Carlos Angel, Xinlong Luo, Axel Espinoza, Joey Wen, Chengjie Zhu, Joseph Tucker, Kalkidan Astatike, Christopher J Phiel, Hatim Sabaawy, Tatiana G Kutateladze, Tao P Wu, Tingting Yao, Chao Lu, Srinivas Ramachandran, Xiaojun Ren

Faculty, Staff and Students Publications

Phase separation is increasingly recognized in facultative heterochromatinization of Polycomb target genes; however, the mechanisms underlying this process remain obscure. Using single-molecule imaging and tracking, we show that individual condensates in mouse embryonic stem cells (mESCs) contain approximately 3 CBX2 molecules and numerous Polycomb repressive complex (PRC)1 and PRC2 subunits and indicate that the composition and dynamics of condensates are developmentally regulated. We reveal that CBX2 clusters PRC2 and controls the spatial distribution of both PRC2 and H3K27me3. Using genomic approaches, we demonstrate that CBX2 binds to condensate initiation sites, which are enriched for PRC2 nucleation sites. CBX2 deletion causes …

Documenting For Success: A Case Study Of A Graduate Writing Retreat, Elliott Rose, Denise Wetzel, Sara C. Kern, Katie O'Hara-Krebs, Laurin Davis, Salah Seoudi, Carmen Cole

Transforming Libraries for Graduate Students

Graduate students often find themselves balancing the demands of research and writing while managing complex academic and personal needs. Writing retreats provide an intentional space for graduate students to focus on their academic goals while supporting community-building, institutional belonging, and a welcoming environment. This proposal outlines a model for academic librarians and staff to plan and implement an effective graduate writing retreat designed to support graduate student academic activities through intentional collaboration and documentation.

Penn State University’s (PSU) Graduate Student Writing Retreat started as an event housed within the University Library’s Science, Technology, Engineering, and Math (STEM) department. The retreat …

On-Resin Diamsar-Conjugated Cd38-Targeted Peptides And Their Inverso And Dimeric-Inverso Analogs For Pet Imaging Of Multiple Myeloma, Amit Kumar Sharma, Rui Tang, Alexander Zheleznyak, Brad Manion, Erin Teubner, Julie L Prior, Tommy Bauer, Michael Riley Dyer, Stephen Lees, Kimberly Kelly, Monica Shokeen

2020-Current year OA Pubs

CD38 is an established biomarker of multiple myeloma (MM), and peptide-based radiopharmaceuticals targeted to this receptor offer a route to molecularly specific imaging. In this work, we identified a novel CD38-targeted peptide sequence (HAPWFRGGGGS) through phage display and synthesized it using automated solid-phase peptide synthesis. The peptide was modified by introducing a PEG

Role Of Plants And Phytochemicals In Promoting Proliferation And Osteogenic Differentiation Of Dental Mesenchymal Stem Cells: A Comprehensive Review, Hala El-Zahar, Essam Abdel-Sattar, Marwa Yousry Moustafa Issa, Shereen N. Raafat, Noha Swilam

Dentistry

Abstract Objectives Dental mesenchymal stem cells (MSCs) represent a promising source for regenerative medicine due to their accessibility and capacity to differentiate into osteoblasts and other lineages. Osteogenic differentiation of dental MSCs is essential for bone formation and is regulated by multiple signaling pathways, cytokines, growth fac‑ tors, and transcription factors. This review aims to summarize the effects of plant-derived extracts and phytochemicals on the proliferation and osteogenic differentiation of dental MSCs. Methods In this review, an extensive literature search was conducted covering studies from the past 10 years, using different online databases (SCOPUS, Google Scholar, PubMed, Web of Science, …

Redesigning Outpatient Chemotherapy Scheduling: A Management Approach To Site-Integrated Operations, Dominick J. Morrone

MUSC Theses and Dissertations

Outpatient infusion centers face persistent scheduling complexity driven by variable treatment durations, coordination between clinics, pharmacy lead times, and constrained staffing. This doctoral project develops and reviews a comprehensive framework for infusion scheduling transformation that integrates workforce role redesign, site‑level communication pathways, and data‑informed workqueue governance. Using a multi‑phase case at a large cancer center as an anchor, the framework specifies responsibilities across central schedulers, on‑site teams, medical coordinators, and nursing; details communication and escalation design (secure messaging and in‑basket use); and outlines training and proficiency tiers. The project synthesizes evidence from scheduling science and time-driven activity-based costing principles to …

Development And Validation Of The Emergency Department Transitions Measure, Sara Beachy, Danielle M. Mccarthy, Julianna Lenoir, Alexzandra Gentsch, Richard W. Hass, Marissa Witmer, Paula Ostroff, Melissa Tupas, Lindsey Shughart, Hailey Shughart, Kristin L. Rising

Jefferson Center for Connected Care Faculty Papers

BACKGROUND: Transitions of care are high-risk periods for patient safety in the emergency department (ED), particularly for patients who are still in the diagnostic process and are discharged with diagnostic uncertainty. Care transitions must be improved for these patients, as one third of discharged ED patients have diagnostic uncertainty. Yet there are no validated measures that assess the quality of care transitions from the ED, limiting the ability to assess the impact of interventions. Thus, we developed and validated the ED Transitions (EDT) measure.

METHODS: This mixed methods study was conducted across a large healthcare system in three phases: item …

Food Insecurity’S Influence On Obesity, Hypertension, And Diabetes In Rural Vermont And Adirondack New York, Lindsay Morse

Walden Dissertations and Doctoral Studies

Food insecurity (FI) is a persistent public health challenge in the United States and disproportionately affects rural communities. Guided by syndemic theory, this quantitative cross-sectional study examined associations between FI and chronic disease outcomes among rural residents of Vermont and the Adirondack region of New York. Social determinants of health screenings and electronic medical records from 35 rural primary care sites were analyzed. Secondary data from n = 72,505 adults were used to evaluate these relationships. Binary logistic regression models assessed obesity, hypertension (HTN), and diabetes (DM), and a multinomial logistic regression model evaluated the combined presence of obesity and …

Genomic Medicine In Pediatrics: What Pediatricians Need To Know Now, Michael Smith, Scott T. Younger

Pediatrics in Practice: A CME Podcast

Genomic medicine is playing an increasingly important role in pediatric care, but it can feel complex for general pediatricians. In this episode of Pediatrics in Practice, Scott Younger, PhD, discusses how genomics is already influencing pediatric diagnosis and care today, common scenarios where genetic insights may be helpful, and why genomic testing can be valuable even when it doesn’t lead to a targeted therapy. This conversation offers practical guidance on when to consider genomics, when to refer, and how pediatricians can partner with genetics and subspecialty teams to support patients and families.

Click here to stream the podcast episode.

Assessing Misidentification Potential When Using Percent Developmental Delay As An Early Intervention Eligibility Criterion, Allison Gladfelter, Sarah Thomas, Christine Nguyen, Sarah O'Connor

CISLL Publications

Purpose:

Method:

Whole-Blood, Concentrated, And Micro–Dose Del Nido Cardioplegia In Adult Cardiac Surgery: A Scoping Review, Christian Iulianelli

Student Works

1. A.     Background/Introduction: Del Nido cardioplegia was originally developed for pediatric cardiac surgery to provide prolonged myocardial protection with a single-dose strategy. Its adoption in adult cardiac surgery has led to multiple modified formulations, including whole-blood, concentrated, and bloodless strategies. Given expanding clinical use and variation in technique, a structured mapping of the adult evidence base is warranted.
2. B.     Methodology: This scoping review followed PRISMA-ScR guidance. PubMed and CINAHL were searched, yielding 88 records. After duplicate removal and screening, 18 studies met inclusion criteria. Data were charted on study design, cardioplegia formulation, patient population, myocardial biomarkers, arrhythmias, renal outcomes, transfusion requirements, …