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Measurement Of Self-Care Agency In A Noninstitutionalized Elderly Population, Julie A. Nelson-Mcevers

Masters Theses

Major focus should be on the elderly's ability to initiate and perform self-care. Interventions to improve health in this age group are most appropriately based on an assessment of their ability to engage in self-care. Orem's framework guided this descriptive study of self-care ability of a convenience sample of 56 seniors residing within a midwestern community. A revision of the Exercise of Self-Care Agency Scale developed by Kearny and Fleischer (1979) was used to measure self-care agency. Relationships between self-care agency and age, gender, living pattern, education, income, and other variables were analyzed. A majority of the subjects perceived their …

A Descriptive Study Of The Needs Of Family Members Of Trauma Patients, Sally Laur Sutkowi

Masters Theses

This study examined the perceived needs of family members of trauma patients using Molter's (1979) Critical Care Family Needs Inventory. The ranking of needs of major and minor trauma patients family members were analyzed to determine differences between these two groups.; A convenience sample of 41 family members of trauma patients were surveyed. They included family members of 17 minor trauma patients and 24 major trauma patients. Minor trauma patients were those patients with Injury Severity Scores 12 or less. Major trauma patients had ISSs scores of 13 or greater. All 45 needs were considered very important by at least …

Perceived Needs Of Parents Of Critically Ill Children, Linda D. Scott

Masters Theses

The purpose of this study was to (a) identify the perceived needs of parents of critically ill hospitalized children, (b) identify parental needs as perceived by critical care nurses, and (c) identify the differences in these perceptions.; A descriptive research design with a non-probability convenience sample was used. The sample consisted of 30 parents or primary caretakers of critically ill children and the responses of 30 pediatric critical care nurses. Data were obtained by a structured interview technique. Data analysis included a comparison of the relationship of parental total scores and the nurses' total scores. No significant differences were found …

Outlook Magazine, Spring 1995

Outlook Magazine

No abstract provided.

The Gtp-Bound Form Of The Yeast Ran/Tc4 Homologue Blocks Nuclear Protein Import And Appearance Of Poly(A)+ Rna In The Cytoplasm., Gabriel Schlenstedt, Claudio Saavedra, Jonathan D. Loeb, Charles N. Cole, Pamela A. Silver

Dartmouth Scholarship

Ran/TC4, a Ras-like GTP-binding protein, and its nucleotide exchanger, RCC1, have been implicated in control of protein movement into the nucleus and cytoplasmic accumulation of mRNA. Saccharomyces cerevisiae contains two homologues of the mammalian Ran/TC4, encoded by the GSP1 and GSP2 genes. We have constructed yeast strains that overproduce either wild-type Gsp1 or a form of Gsp1 with glycine-21 converted to valine (Gsp1-G21V), which we show stabilizes the GTP-bound form. Cells producing Gsp1-G21V have defects in localization of nuclear proteins; nuclear proteins accumulate in the cytoplasm following galactose induction of Gsp1-G21V. Similarly, cells producing Gsp1-G21V retain poly(A)+ RNA in their …

Special Care Units: Specialization In Long-Term Care, Marilynn Anne Schaus

Theses

i99SThere were two purposes of this study. The first was to conduct a literature review of the research findings on special care units. These units are segregated areas of a nursing home specializing in the care of Alzheimer's and dementia related patients. The purpose of the research was to determine what constitutes a special care unit, what is "special'' about the units and the units effectiveness in the treatment of dementia patients.

The second purpose of the study was to compare existing special care units in the St. Louis Metropolitan area with the research findings. Eight nursing facilities with a …

Violence In The Womb, Violence In The World: The Effects Of Fetal Exposure To Alcohol, Drugs, And Nicotine, Aileen R. Wynne

Theses

This project will focus on prenatal substance abuse and the long term adverse effects of birth defects in the offspring of these women. The focus will discuss a relationship between the drug exposed fetus as a predictor of later development of behavior problems , running along the continuum from antisocial behavior to aggression and violence.

Research will show that of the three leading contributors to birth defects , Fetal Alcohol Syndrome is number one, greater than Downs Syndrome and Spina Bifida. The risk factors of prenatal substance abuse will be described as use of alcohol , other drugs , and …

Nsu Master's Program In Speech-Language Pathology 1995–1996 Catalog (Includes Application And Admission Forms), Nova Southeastern University

Abraham S. Fischler College of Education and School of Criminal Justice College Archive

No abstract provided.

The Rotational Orientation Of The T Cell Receptor Bound To Peptide: Mhc, Sangwook Tim Yoon

Yale Medicine Thesis Digital Library

The T cell receptor (TCR) is the multi-chained cell surface molecule that mediates the specific recognition of antigen by the T cell. The alpha and beta chains of the TCR are members of the immunoglobulin gene superfamily and form the antigen binding components of the TCR. Although the function of alphabeta-TCRs has been well characterized, less is known about their molecular structure. Current three-dimensional structural models of TCR are based on the similarities in primary sequence between the TCR with immunoglobulin genes. Models of the ternary structure of the TCR and MHC complex have also been proposed. These models, however, …

Doing More With Less: The Marie Stopes Clinics In Sierra Leone, Nahid Toubia, Grace Ebun Delano

Poverty, Gender, and Youth

This edition of Quality/Calidad/Qualité reports on the Marie Stopes Sierra Leone (MSSL) organization which pursues its goals with compassion and ambition, despite seemingly insurmountable economic hardships. MSSL has established a service model that many programs in richer countries should try to imitate. Several particularly important lessons emerged, including: creative, skillful management, well-organized and flexible financial administration, and human motivation and perseverance can enable an organization to overcome financial difficulties; family planning is an integral part of people's reproductive and general health concerns and can dovetail with concern for development in useful and practical ways; men appreciate being involved in the …

The Coletivo: A Feminist Sexuality And Health Collective In Brazil, Margarita Diaz, Debbie Rogow, Jose Barzelatto

Poverty, Gender, and Youth

This issue of Quality/Calidad/Qualité tells the story of a group of Brazilian women who came together in 1981 with the shared belief—not as widely understood then as it is now—that conventional approaches to women's health and family planning services were overly medicalized, incapable of dealing with the relationship between sexuality and contraception, and disempowering to clients. They started the Coletivo which runs a clinic, a training institute, and a public education program that has “given voice” to thousands of women, provided leadership to the Brazilian government and women’s health movement, and has been active in research and international policy affairs. …

Tuberculosis And The Power Of The State: Toward The Development Of Rational Standards For The Review Of Compulsory Public Health Powers, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

This article uses tuberculosis as the paradigm for exploring rational standards for the exercise of compulsory public health powers. Extant doctrine in disability and constitutional law provides a lens for examining judicial review of state interventions. The author first sets out the central epidemiological and biological aspects of tuberculosis to demonstrate the strength of the governmental interest in curtailing the epidemic. Second, he examines the interventions of testing, screening, and confinement of persons with tuberculosis, where he focuses on two congregate settings--correctional and health care facilities--that present substantial health risks and are principal foci for the exercise of state intervention. …

What We Do And Do Not Know About The Menstrual Cycle Or, Questions Scientists Could Be Asking, Sioban D. Harlow, Sara A. Ephross

Reproductive Health

The objective of this paper is to consider from a public health perspective the types of questions researchers might be asking about the relationship between menstrual function and women’s health, and to evaluate to the extent to which these questions have or have not been addressed by the scientific community. Based on the findings in this report, it is obvious that a comprehensive program of research is needed in order to begin filling the myriad gaps in scientific knowledge about the menstrual cycle. Given the lack of knowledge about many fundamental aspects of menstrual function and about linkages between the …

Sexual Coercion And Reproductive Health: A Focus On Research, Lori L. Heise, Kirsten Moore, Nahid Toubia

Reproductive Health

Gender-based violence is ignored or denied in most societies and neglected by health professionals and researchers, yet it persists in almost all societies, and, in some, it is on the increase. This report is aimed at those in the family planning/reproductive health field who desire to conduct research or implement programs to address sexual violence and its impact on women's reproductive health. Furthermore, it contributes to a better understanding of the context of sexual coercion as well as its causes and consequences. The ideas presented herein are derived largely from a two-day meeting jointly organized by the Ebert Program in …

Effects Of Eeg Biofeedback Treatment On Attention-Deficit Disorders And Learning Disabilities, Kathleen M. Randazzo

Theses

The goal of this study was to measure the effects of EEG biofeedback treatment on attention-deficit disordered and learning disabled subjects. The study was conducted in a private psychologist's office, located in St . Louis County, a suburban section of the mid-West. Subjects for the study were chosen from children and adolescents who had been referred for academic and behavioral problems . The treatment group was composed of thirty eight subjects, who had been diagnosed as having attention deficit disorder and/or a learning disability . A one-group pretest-posttest research design was used. The dependent variables were : theta to beta …

A 31p, 13c, And 1h Nmr Study Of The Direct Interaction Of Cocaine Hc1 And Magnesium Atp, Gene Lee Bangs, Roger M. Hawk, Debi Patangia

Journal of the Arkansas Academy of Science

In vivo 31P NMR studies recently have shown that cocaine causes an imbalance of the free magnesium in the brain which results in pH lowering, ischemia, and even death. This direct interaction with the free Mg+2 inthe brain also affects the Ca+2 balance which controls arterial and vascular contraction. This research has addressed the mechanism of the cocaine interaction withmagnesium adenosine 5-triphosphate (ATP) using 31P, 13C, and 1H NMR using a Bruker 200 MHz nuclear magnetic resonance (NMR) system. Data are presented and discussed which shows that cocaine and ATP form a complex species which directly affects the NMR spectra.

The Effect Of Eccentric And Concentric Training On The Size And Strength Of Human Skeletal Muscle, Haydn J. N. Mcdonald

Theses : Honours

The objective of this study was to determine if the high forces generated through eccentric contractions, and the subsequent damage sustained, contributes to greater growth and force increase in human skeletal muscle than other contraction types, and whether damage from eccentric exercise effects the increase in torque and muscle size expected after a progressive concentric strength training program. 20 healthy subjects were split into four groups which participated in 3 different training protocols, with one group serving as the control (C). Groups underwent either concentric training (CT), eccentric damage (ED), or a combination of the two protocols (DC) with the …

Localisation Of The Gene For A Novel Form Of Charcot-Marie-Tooth Disease In An Isolated Population, Kaite Honeyman

Theses : Honours

Localising the gene for a previously undescribed autosomal recessive form of CMT involved the use of a relatively new approach to rapid genome screening based on the identification of segments which are inherited identical by descent (IBD) from common founding ancestors. It is most feasible for populations which have been founded relatively recently (say less than 25 generations) and which have remained relatively isolated either geographically or culturally. The method is not suitable for highly inbred populations, that is with first and second cousin matings, as many segments will be inherited by chance. It appears to be a suitable screening …

Cellular Mechanisms Underlying Myogenic Reactivity In Isolated Arterioles, Hui Zou

Theses and Dissertations in Biomedical Sciences

The myogenic reactivity provides one of the principal mechanisms for blood flow autoregulation. The aims of the performed studies described in this dissertation were to test the role of [Ca²⁺]_i and MLC phosphorylation in arteriolar myogenic reactivity and further examine the source(s) of activator Ca²⁺ required to initiate and maintain myogenic vasoconstriction. In addition, the possible underlying mechanism of contractile protein expression was also addressed.

These studies used male Sprague Dawley rats of 200 ~ 350 grams body weight. Experiments were carried out using rat cremaster first order arterioles and mesenteric vessels. Gel electrophoresis and immunoblotting …

Faculty Publications 1994, Lsu Health Sciences Center New Orleans

Historical Faculty Publications

This Faculty bibliography contains 565 publications.

Nmda Receptor-Mediated Synaptic Plasticity In Developing Mammalian Visual Pathways, Gregory S. Perens

Theses and Dissertations

Precise connections in many mammalian nervous systems require a great deal of remodeling during development. In the visual system, many excess synapses are originally formed in the lateral geniculate nucleus and striate cortex. Only the correct set of axon terminals are retained during normal development, while imprecise ones withdraw. The mechanism by which only correct axons are retained requires neural activity, and may be regulated by specific receptors at synapses.

The transmission of neural signals at these synapses is carried out in part by the glutamate-activated NMDA receptor. It is hypothesized that NMDA receptor activation plays a crucial role in …

A Monoclonal Antibody To The Gp120-Cd4 Complex Has Differential Effects On Hiv-Induced Syncytium Formation And Viral Infectivity, Krystyna Konopka, Elizabeth Pretzer, F. Celada, Nejat Düzgüneş

All Dugoni School of Dentistry Faculty Articles

A murine monoclonal antibody (MAb F-91-55) raised against the complex of soluble CD4 and human immunodeficiency virus type 1 (HIV-1) gp120 had previously been found to inhibit syncytium formation without inhibiting the interaction of CD4 with gp120, and its binding site was localized within the first two domains (D1/D2) of CD4. We investigated whether this antibody inhibited the infectivity of HIV-1 in the CD4+ T cell lines A3.01, Sup-T1 and H9. We also examined the effect of the antibody on syncytium formation between these cells and chronically infected H9 cells. Syncytium formation was found to depend critically on the incubation …

Dissociation Of Centrosome Replication Events From Cycles Of Dna Synthesis And Mitotic Division In Hydroxyurea-Arrested Chinese Hamster Ovary Cells, Ron Balczon, Liming Bao, Warren E. Zimmer, Kevin Brown, Raymond P. Zinkowski, B. R. Brinkley

University Faculty and Staff Publications

Relatively little is known about the mechanisms used by somatic cells to regulate the replication of the centrosome complex. Centrosome doubling was studied in CHO cells by electron microscopy and immunofluorescence microscopy using human autoimmune anticentrosome antiserum, and by Northern blotting using the cDNA encoding portion of the centrosome autoantigen pericentriolar material (PCM)-1. Centrosome doubling could be dissociated from cycles of DNA synthesis and mitotic division by arresting cells at the G1/S boundary of the cell cycle using either hydroxyurea or aphidicolin. Immunofluorescence micros-copy using SPJ human autoimmune anticentrosome antiserum demonstrated that arrested cells were able to undergo numerous rounds …

Certain Canine Weakly Β-Hemolytic Intestinal Spirochetes Are Phenotypically And Genotypically Related To Spirochetes Associated With Human And Porcine Intestinal Spirochetosis, Gerald E. Duhamel, Nagaraja Muniappa, Michelle R. Mathiesen, J. L. Johnson, J. Toth, R. O. Elder, A. R. Doster

School of Veterinary and Biomedical Sciences: Faculty Publications

Four canine weakly β-hemolytic intestinal spirochetes associated with intestinal spirochetosis (IS-associated WBHIS) were compared with IS-associated human and porcine WBHIS and the type species for Serpulina hyodysenteriae and S. innocens by using phenotypic and genotypic parameters. The IS-associated canine, human, and porcine WBHIS belonged to a phyletic group distinct from but related to previously described Serpulina type species.

Cluster Analysis Of The Coprolites From Antelope House: Implications For Anasazi Diet And Cuisine, Mark Q. Sutton, Karl Reinhard

Karl Reinhard Publications

This paper reports on a cluster analysis of 155 coprolites from Antelope House, a prehistoric Anasazi site in Canyon de Chelly, Arizona. The analysis revealed three primary clusters; whole kernel maize, milled maize, and nonmaize, which we believe to represent seasonal- and preference-related cuisine. Protein residue analysis on a subsample of the specimens added depth to the analysis.

Survey Of Omega-3 Fatty Acids In Diets Of Midwest Low-Income Pregnant Women, Nancy M. Lewis, Anne C. Widga, Janet S. Buck, Andrea M. Frederick

Department of Nutrition and Health Sciences: Faculty Publications

The objectives of this project were to detennine the omega-3 fatty acid (ω-3 FA) consumption of low-income pregnant women, and to identify food sources of ω-3 FA in their diets. Thirty women provided three days of dietary intake that were analyzed using the Food Processor Plus computer program. Mean daily consumption of ω-3 FA was 1.060 ± 0.030 g/day. The major form of the ω-3 FA was α-linolenic acid (α-LNA; 93%), with less from eicosapentanoic acid (EPA; 2%), and docosahexanoic acid (DHA; 5%). Foods that provided the most α-LNA were fats, oils, salad dressings, and milk products. EPA …

The Immune System, Betty Bierut Gallucci, Donna O. Mccarthy

College of Nursing Faculty Research and Publications

Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being tested as pharmaceutical agents. Biotherapy connotes the administration of products (1) that are coded by the mammalian genome; (2) that modify the expression of mammalian genes; or (3) that stimulate the immune system. In this chapter the discussion of the immune system will be limited primarily to topics relevant to cancer or autoimmune diseases. Because understanding the new biological agents …

Perceptions Of Control And Satisfaction With Hospital Birth Experiences For First-Time Mothers, Clelia Tedeschi

Theses : Honours

Satisfaction with childbirth is associated with women's future emotional wellbeing. This study examined whether first- time mother's antenatal expectations, postnatal evaluations of control during labour and delivery, and the discrepancy between expectations and evaluations were significant predictors of women's satisfaction with their childbirth experiences. The effect of medical interventions (e.g., obstetrical interventions and pain relief medication) on women's perceptions of control and satisfaction was also examined. The purposive sample of eighty first-time mothers, mean age 26 years (excluding women who had caesareans) delivered at the public hospital where they attended antenatal classes. During their fourth antenatal class women completed a …

Long Term Restoration Of Peak Torque, Endurance And Muscle Activation Post Anterior Cruciate Ligament Reconstruction, Darryl Alan Turner

Theses : Honours

In recent years, Accelerated Rehabilitation (A.R.) protocols have been used following Anterior Cruciate Ligament (A.C.L.) reconstructions, the longer term effects of these programs are seldom analysed. This study examined musculoskeletal mechanisms that might affect long term functional restoration, the control subjects (n = 19) of mixed age and gender, had no previous knee deficiencies and were recreationally fit. The experimental subjects (n = 17) had undergone intra-articular A.C.L reconstruction, using bone patellar-tendon bone grafts performed by the same surgeon and had also participated in the A.R. protocol, similar to that described by Shelbourne and Nitz (1990). The experimental group attended …

Estimates Of Elderly At Nutritional Risk From The Determine Your Nutritional Health Checklist: The 1994 Northeast Florida Nutrition Screening Initiative, Lynn Marie Brokiewicz

UNF Graduate Theses and Dissertations

This study examined associations among the nutritional risks, the risk levels, and the ages of independently living elderly. The Checklist of the Nutrition Screening Initiative (NSI) was administered to a purposive sample of 1004 Northeast Florida elderly to estimate an age-profile at risk for malnutrition. Checklist nutritional scores (cumulative of ten risks) were grouped into risk levels of low (scores 0-2, 64.3%), moderate (3-5, 29.5%), and high (6 and greater, 24.2%). Within each level, Checklists were grouped by respondents' age into young-old (60-74), old-old (75-79), and fragile-old (80-102). Eight nutritional risks' distribution across risk levels was significantly greater in respondents …