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Articles 5521 - 5550 of 96355
Full-Text Articles in Entire DC Network
The Latest In Resuscitation Research: Highlights From The 2024 American Heart Association's Resuscitation Science Symposium, Gabriela M Galli, Aarthi Kaviyarasu, Sachin Agarwal, Catherine R Counts, Tommaso Scquizzato, Betty Yang, Clark G Owyang, Ryan Coute, Simon Orlob, Lindsay Shepard, Saleem Halablab, James Horowitz, Sarah Perman, Ryan Morgan, Anne Grossestreuer, Jacob Vine, Nicholas Johnson, Luke Andrea, Ari Moskowitz, Benjamin Abella, Cameron Dezfulian, Walid H Farooqi, Felipe Teran
The Latest In Resuscitation Research: Highlights From The 2024 American Heart Association's Resuscitation Science Symposium, Gabriela M Galli, Aarthi Kaviyarasu, Sachin Agarwal, Catherine R Counts, Tommaso Scquizzato, Betty Yang, Clark G Owyang, Ryan Coute, Simon Orlob, Lindsay Shepard, Saleem Halablab, James Horowitz, Sarah Perman, Ryan Morgan, Anne Grossestreuer, Jacob Vine, Nicholas Johnson, Luke Andrea, Ari Moskowitz, Benjamin Abella, Cameron Dezfulian, Walid H Farooqi, Felipe Teran
Faculty, Staff and Students Publications
No abstract provided.
Phosphorylation Of Ryr1 At Ser2902 Decreases Ca2+ Leak In Skeletal Muscle And Susceptibility To Malignant Hyperthermia And Heat Stroke, Rachel Sue Zhen Yee, Chang Seok Lee, Ting Chang, Sung Yun Jung, Omar Yousif, Courtney Cavazos, John Colyer, Filip Van Petegem, George G Rodney, Susan L Hamilton
Phosphorylation Of Ryr1 At Ser2902 Decreases Ca2+ Leak In Skeletal Muscle And Susceptibility To Malignant Hyperthermia And Heat Stroke, Rachel Sue Zhen Yee, Chang Seok Lee, Ting Chang, Sung Yun Jung, Omar Yousif, Courtney Cavazos, John Colyer, Filip Van Petegem, George G Rodney, Susan L Hamilton
Faculty, Staff and Students Publications
The ryanodine receptor 1 (RYR1) is the sarcoplasmic reticulum (SR) Ca2+ release channel required for both skeletal muscle contraction and Ca2+ leak. Mutations in RYR1 cause malignant hyperthermia susceptibility (MHS) and enhanced sensitivity to heat stroke (ESHS), which can result in death due to excessive skeletal muscle thermogenesis upon exposure to volatile anesthetics or heat. Here, we investigated the molecular and physiological functions of phosphorylation of RYR1 at Ser2902 by the kinase SPEG (striated muscle preferentially expressed protein). Muscle from SPEG-deficient mice expressing RYR1 with a Ser2902 →Asp2902 (S2902D) point mutation to mimic phosphorylation by SPEG showed decreased SR Ca2+ …
Biliverdin Reductase A Is A Major Determinant Of Protective Nrf2 Signaling, Chirag Vasavda, Ruchita Kothari, Navneet Ammal Kaidery, Suwarna Chakraborty, Sunil Jamuna Tripathi, Ryan S Dhindsa, Cristina Ricco, Shruthi Shanmukha, Samaneh Saberi, Julia E Lefler, Priyanka Kothari, Kalyani Chaubey, Adele M Snowman, Michael C Ostrowski, Eugenio Barone, Lakshminarayan M Iyer, L Aravind, Sudarshana M Sharma, Andrew A Pieper, Bobby Thomas, Solomon H Snyder, Bindu D Paul
Biliverdin Reductase A Is A Major Determinant Of Protective Nrf2 Signaling, Chirag Vasavda, Ruchita Kothari, Navneet Ammal Kaidery, Suwarna Chakraborty, Sunil Jamuna Tripathi, Ryan S Dhindsa, Cristina Ricco, Shruthi Shanmukha, Samaneh Saberi, Julia E Lefler, Priyanka Kothari, Kalyani Chaubey, Adele M Snowman, Michael C Ostrowski, Eugenio Barone, Lakshminarayan M Iyer, L Aravind, Sudarshana M Sharma, Andrew A Pieper, Bobby Thomas, Solomon H Snyder, Bindu D Paul
Duncan NRI Faculty and Staff Publications
Biliverdin reductase A (BVRA), the terminal enzyme in heme catabolism, generates the neuroprotective and lipophilic antioxidant bilirubin. Here, we identify a nonenzymatic role for BVRA in redox regulation. Through phylogenetic, genetic, biochemical, and enzymatic assays, we found that BVRA exerts critical nonenzymatic antioxidant activity. Transcriptomic analyses further revealed that BVRA physically and genetically interacts with nuclear factor erythroid-derived factor-like 2 (NRF2), a major transcriptional regulator of cellular redox signaling. ChIP-seq and RNA-seq analyses reveal that BVRA and NRF2 coordinate the expression of antioxidant genes, many of which are typically dysregulated in neurodegenerative conditions such as Alzheimer's disease. Thus, this noncanonical …
Keys For Success When Using An Integrative Interprofessional Teaching Model: A Synergistic Approach, Hon-Vu Quang Duong, Nina Marcellus, Sandip Thanki
Keys For Success When Using An Integrative Interprofessional Teaching Model: A Synergistic Approach, Hon-Vu Quang Duong, Nina Marcellus, Sandip Thanki
Journal of Educational Research and Practice
This study presents a longitudinal analysis of the qualitative experiences and quantitative outcomes associated with integrative, interdisciplinary teaching in the context of a specific nursing course, Pathophysiology (NURS 337), at a public, 4-year, state college (now university). Spanning an 8-year period, from 2014–2022, the research compares two distinct student cohorts: one exposed to collaborative interdisciplinary teaching methods, the other to traditional non-collaborative instructional approaches. The findings reveal that integrative, interdisciplinary teaching yielded significant benefits across multiple metrics. Notably, integrative, interdisciplinary teaching contributed to a more normalized distribution of grades, higher student retention rates, and an elevated cumulative GPA at the …
Alloplastic Implants For Rhinoplasty: A Systematic Review And Meta-Analysis Of Clinical Outcomes And Complications, Rafeni Bunga Cikita, Beta Subakti Nataadmaja
Alloplastic Implants For Rhinoplasty: A Systematic Review And Meta-Analysis Of Clinical Outcomes And Complications, Rafeni Bunga Cikita, Beta Subakti Nataadmaja
Folia Medica Indonesiana
Alloplastic implants emphasize the importance of a comprehensive understanding of both clinical and histological aspects, which are attributed to enhancing patient satisfaction and surgical success rates. The study aims to assess the viability of different implant materials and their related risks over time. A systematic literature search was conducted across multiple databases, including PubMed, Cochrane, and EBSCOhost, to identify 79 records. After eliminating duplicates and applying specific inclusion and exclusion criteria, four new studies were included for evaluation, focusing on postoperative outcomes related to alloplastic implants in rhinoplasty. Late-onset inflammation in non-healthy capsules required removal and showed histological damage. One …
10.06.2025 Ored Connect, Liz Williamson
10.06.2025 Ored Connect, Liz Williamson
ORED Newsletter
- Field Fest
- AAAS Membership
- MIG Application Opportunity
- Contest to Promote Safe Lab Practices
Examining Student Resource Choice, Perception, And Self-Regulation In A Flipped Undergraduate Microbiology Lecture Course, Sarah Sletten
Examining Student Resource Choice, Perception, And Self-Regulation In A Flipped Undergraduate Microbiology Lecture Course, Sarah Sletten
Biomedical Sciences Faculty Publications
This study examines student resource choice, perceptions, and self-regulated learning (SRL) in preparation for a flipped undergraduate microbiology course. Drawing on Expectancy-Value Theory, the investigation explored whether students prefer video lectures or complete note sets for pre-class preparation, how SRL strategies evolve over time, and the relationship between flipped classroom perceptions and in-class engagement. Data were collected across multiple course units using surveys—including a modified Motivated Strategies for Learning Questionnaire—and analysis of resource selection and classroom participation. The results indicate a strong and increasing preference for slides over video lectures. Additionally, significant increases in higher-order cognitive strategies were observed alongside …
Intouch Week Of October 6, 2025, New York Medical College
Intouch Week Of October 6, 2025, New York Medical College
InTouch
- NYMC Goes Pink for Breast Cancer Awareness Month
- Summer Research Fellowships Empower Medical Students to Explore, Innovate, and Lead
- International Symposium on Adolescent and Young Adult NHL Has Far Reach
- A Look Inside NYMC with the 2025-2026 Social Media Ambassadors
- SOM Welcomes New Faculty
- Pet the Stress Away Brings Joy to NYMC
- Stay Warm with Savings on Hoodies
- In The Community: College Joins Forces at Westchester Heart Walk to Fight Heart Disease and Stroke
- In The Community: SHSP Students and Faculty Partner with the White Plains Youth Bureau for Community Health and Wellness Day
- Faculty Spotlight: Christopher Whitehurst, Ph.D., Cracks …
Perceptions Of Whole Plant-Based Diets And Weight Among Hispanics In Miami, Florida, Zoraida Powell
Perceptions Of Whole Plant-Based Diets And Weight Among Hispanics In Miami, Florida, Zoraida Powell
Walden Dissertations and Doctoral Studies
Being overweight or obese poses major public health concerns and contributes to the development of chronic illnesses. While researchers have explored how a total plant-based diet impacts excess body weight or obesity, there is still a lack of clarity about how Hispanics living in Miami, FL, perceive or understand this diet concerning overweight and obesity. Using a generic qualitative approach, this study was conducted on how Hispanics in Miami, FL, understand and view a whole plant-based diet (WPBD) for preventing and reducing overweight and obesity. Through interviews with 14 diverse Hispanic participants, the study revealed that they see WPBD as …
Rurality’S Impact On Alaska Native Elders’ Levels Of Physical Activity And Obesity, Jessie Doherty
Rurality’S Impact On Alaska Native Elders’ Levels Of Physical Activity And Obesity, Jessie Doherty
Walden Dissertations and Doctoral Studies
While there have been studies on obesity levels and physical activity levels across many populations and age groups, few studies have focused on Alaska Native Elders. The purpose of this study was to examine rurality (urban vs. rural counties), physical activity, and obesity level while controlling for sex, self-reported loneliness, and self-reported stress. The theoretical foundation for this study was based on the socio-ecological model (SEM), and the research questions in this study explored how rurality impacted obesity levels and how rurality impacted physical activity levels in Alaska Native Elders. The methodology of this study was a quantitative cross-sectional design …
Phytochemisty And Antioxidant Activity Of Ethanol, Ethyl Acetate, And N-Hexane Extracts Of Suruhan Leaves (Peperomia Pellucida), Ade Arsianti, Steven Gill, Diyah Kristanty
Phytochemisty And Antioxidant Activity Of Ethanol, Ethyl Acetate, And N-Hexane Extracts Of Suruhan Leaves (Peperomia Pellucida), Ade Arsianti, Steven Gill, Diyah Kristanty
Indonesian Journal of Medical Chemistry and Bioinformatics
Background: Free radicals are natural byproducts of cellular metabolism, in which, their excessive accumulation can lead to oxidative stress, which plays a key role in the development of various chronic diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions. Antioxidants are compounds capable of scavenging free radicals and minimizing oxidative damage. Peperomia pellucida, commonly known as Suruhan leaves, is a tropical herb traditionally used in folk medicine that contain bioactive compounds correlated with a strong radical-scavenging activity, suggesting its potential as a natural antioxidant source. This study aims to conduct a phytochemical analysis and evaluate the antioxidant activity of ethanol, …
Atg16l1 Controls Mammalian Vacuolar Proton Atpase, Thabata L A Duque, Masroor Paddar, Einar Trosdal, Ruheena Javed, Lee Allers, Michal H Mudd, Prithvi Akepati, Soumya R Mishra, Michelle Salemi, Brett Phinney, Shawn B Bratton, Thomas Wileman, Vojo Deretic
Atg16l1 Controls Mammalian Vacuolar Proton Atpase, Thabata L A Duque, Masroor Paddar, Einar Trosdal, Ruheena Javed, Lee Allers, Michal H Mudd, Prithvi Akepati, Soumya R Mishra, Michelle Salemi, Brett Phinney, Shawn B Bratton, Thomas Wileman, Vojo Deretic
Faculty, Staff and Student Publications
The mechanisms governing mammalian proton pump V-ATPase function are of fundamental and medical interest. The assembly and disassembly of cytoplasmic V1 domain with the membrane-embedded V0 domain of V-ATPase is a key aspect of V-ATPase localization and function. Here, we show that the mammalian protein ATG16L1, primarily appreciated for its role in canonical autophagy and in noncanonical membrane atg8ylation processes, controls V-ATPase. ATG16L1 knockout elevated V-ATPase activity, increased V1 presence on endomembranes, and increased the number of acidified intracellular compartments. ATG16L1's ability to efficiently bind V-ATPase was required for its inhibitory role in endolysosomal acidification and for control of Mycobacterium …
Exploring The Correlation Between Pupil Distance And Myopia Prevalence: An Observational Bioanthropology Study In Surabaya, Anggitha Hayuning Kinasih, Dwi Martha Nur Aditya, Y Adhimas Setyo Wicaksono
Exploring The Correlation Between Pupil Distance And Myopia Prevalence: An Observational Bioanthropology Study In Surabaya, Anggitha Hayuning Kinasih, Dwi Martha Nur Aditya, Y Adhimas Setyo Wicaksono
Folia Medica Indonesiana
Bioanthropology integrates biological and cultural perspectives, thereby enhancing our understanding of human health across populations. Myopia is a significant refractive error affecting potentially 2.5 billion people globally by the end of the decade. Bioanthropological theories suggest that pupil diameter and distance contribute to axial elongation and the progression of myopia. Nevertheless, current literature lacks empirical validation through rigorous hypothesis testing, highlighting a gap in comprehension. The research explores the relationship between pupil distance and the incidence of myopia via empirical assessments in Surabaya. An observational cross-sectional study was conducted, which involved pupil distance measurements and eye refraction assessments. Inclusion criteria …
Practicing With Intent: How To Teach An Old Dogma New Tricks, Matthew C Phillips, Kusha Davar, Sarah Freling, Steven Y C Tong, Todd C Lee, Emily G Mcdonald, Travis B Nielsen, Noah Wald-Dickler, Alfredo J Mena Lora, Rachael A Lee, Fergus Hamilton, Daniel M Musher, Rodrigo P L Costa, Bassam Ghanem, Rachel Baden, Brad Spellberg
Practicing With Intent: How To Teach An Old Dogma New Tricks, Matthew C Phillips, Kusha Davar, Sarah Freling, Steven Y C Tong, Todd C Lee, Emily G Mcdonald, Travis B Nielsen, Noah Wald-Dickler, Alfredo J Mena Lora, Rachael A Lee, Fergus Hamilton, Daniel M Musher, Rodrigo P L Costa, Bassam Ghanem, Rachel Baden, Brad Spellberg
Faculty, Staff and Students Publications
Clinicians are constantly bombarded with an onslaught of newly published data, yet they must make clinical decisions despite a dearth of clinical data. Sometimes, they may fall back on clinical practices entrenched by experience, unaware that they are upheld by dogmatic tradition rather than robust evidence. Ideally, the totality of evidence must be assessed and utilized for clinical decision-making, irrespective of entrenched orthodoxy. Here, we explore the questions, how much evidence is needed to revise established clinical practices and, more fundamentally, can data alone truly catalyze such shifts.
Strain-Specific Variability In Viral Kinetics, Cytokine Response, And Cellular Damage In Air-Liquid Cultures Of Human Nasal Organoids After Infection With Sars-Cov-2, Gina M Aloisio, Trevor J Mcbride, Letisha Aideyan, Emily M Schultz, Ashley M Murray, Anubama Rajan, Erin G Nicholson, David Henke, Laura Ferlic-Stark, Amal Kambal, Hannah L Johnson, Elina A Mosa, Fabio Stossi, Sarah E Blutt, Pedro A Piedra, Vasanthi Avadhanula
Strain-Specific Variability In Viral Kinetics, Cytokine Response, And Cellular Damage In Air-Liquid Cultures Of Human Nasal Organoids After Infection With Sars-Cov-2, Gina M Aloisio, Trevor J Mcbride, Letisha Aideyan, Emily M Schultz, Ashley M Murray, Anubama Rajan, Erin G Nicholson, David Henke, Laura Ferlic-Stark, Amal Kambal, Hannah L Johnson, Elina A Mosa, Fabio Stossi, Sarah E Blutt, Pedro A Piedra, Vasanthi Avadhanula
Faculty, Staff and Students Publications
SARS-CoV-2 variants have demonstrated distinct epidemiological patterns and clinical presentations throughout the COVID-19 pandemic. Understanding variant-specific differences at the respiratory epithelium is crucial for understanding their pathogenesis. Here, we utilized human nasal organoid air-liquid interface (HNO-ALI) cell cultures to compare the viral replication kinetics, innate immune response, and epithelial damage of six different strains of SARS-CoV-2 (B.1.2, WA, Alpha, Beta, Delta, and Omicron). All variants replicated efficiently in HNO-ALIs, but with distinct replication kinetic patterns. The Delta variant exhibited delayed replication kinetics, achieving a steady state at 6 days post-infection compared to 3 days for other variants. Cytokine analysis revealed …
Improved Allele Frequencies In Gnomad Through Local Ancestry Inference, Pragati Kore, Michael W Wilson, Grace Tiao, Katherine Chao, Philip W Darnowsky, Nicholas A Watts, Jessica Honorato Mauer, Samantha M Baxter, Genome Aggregation Database Consortium, Heidi L Rehm, Mark J Daly, Konrad J Karczewski, Elizabeth G Atkinson
Improved Allele Frequencies In Gnomad Through Local Ancestry Inference, Pragati Kore, Michael W Wilson, Grace Tiao, Katherine Chao, Philip W Darnowsky, Nicholas A Watts, Jessica Honorato Mauer, Samantha M Baxter, Genome Aggregation Database Consortium, Heidi L Rehm, Mark J Daly, Konrad J Karczewski, Elizabeth G Atkinson
Faculty, Staff and Students Publications
The Genome Aggregation Database (gnomAD) is a foundational resource for allele frequency data, widely used in genomic research and clinical interpretation. However, traditional estimates rely on individual-level genetic ancestry groupings that may obscure variation in recently admixed populations. To improve resolution, we applied local ancestry inference (LAI) to over 27 million variants in two admixed groups: Admixed American (n = 7612) and African/African American (n = 20,250), deriving ancestry-specific allele frequencies. We show that 78.5% and 85.1% of variants in these groups, respectively, exhibit at least a twofold difference in ancestry-specific frequencies. Moreover, 81.49% of variants with LAI information would …
Atg Conjugation-Dependent/Independent Mechanisms Underlie Lysosomal Stress-Induced Tfeb Regulation, Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, Mengying Cui, Jlenia Monfregola, Kohei Nishino, Andrea Ballabio, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura
Atg Conjugation-Dependent/Independent Mechanisms Underlie Lysosomal Stress-Induced Tfeb Regulation, Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, Mengying Cui, Jlenia Monfregola, Kohei Nishino, Andrea Ballabio, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura
Duncan NRI Faculty and Staff Publications
TFEB, a master regulator of autophagy and lysosomal biogenesis, is activated by several cellular stresses including lysosomal damage, but its underlying mechanism is unclear. TFEB activation during lysosomal damage depends on the ATG conjugation system, which mediates lipidation of ATG8 proteins. Here, we newly identify ATG conjugation-independent TFEB regulation that precedes ATG conjugation-dependent regulation, designated Modes I and II, respectively. We reveal unique regulators of TFEB in each mode: APEX1 in Mode I and CCT7 and/or TRIP6 in Mode II. APEX1 interacts with TFEB independently of the ATG conjugation system, and is required for TFEB stability, while both CCT7 and …
The Donut Hole Fall 2025, Medicare Donations & Design Committee
The Donut Hole Fall 2025, Medicare Donations & Design Committee
Donut Hole Newsletter
- 🗓 Fall 2025 Event Calendar – 11 total events (nine in-person across six cities and two virtual events).
- 🌞 Oak Park Summer Event – Experiences and outcomes from our Summer Medicare Health Fair.
- 💆 Class Wellness Activities – Highlights of faculty- and staff-led sessions and student experiences.
- 🤝 Mentor-Mentee Program – CV review, mock interviews, and longitudinal mentorships based on shared interests, including interviews with current participants.
- 👩🏫 New Medicare Faculty Introductions
- …and much more!
Causal Ai-Based Clinical And Radiomic Analysis For Optimizing Patient Selection In Combined Immunotherapy And Sabr In Early-Stage Nsclc: A Secondary Analysis Of The Phase Ii I-Sabr Trial, Maliazurina B Saad, Eman Showkatian, Vivek Verma, Qasem Al-Tashi, Muhammad Aminu, Xinyan Xu, Muhamed Qayati Mohamed, Morteza Salehjahromi, Sheeba J Sujit, Yuliya Kitsel, Steven H Lin, Zhongxing Liao, Saumil Gandhi, David Qian, David Jaffray, Caroline Chung, Natalie I Vokes, Jianjun Zhang, J Jack Lee, John V Heymach, Jia Wu, Joe Y Chang
Causal Ai-Based Clinical And Radiomic Analysis For Optimizing Patient Selection In Combined Immunotherapy And Sabr In Early-Stage Nsclc: A Secondary Analysis Of The Phase Ii I-Sabr Trial, Maliazurina B Saad, Eman Showkatian, Vivek Verma, Qasem Al-Tashi, Muhammad Aminu, Xinyan Xu, Muhamed Qayati Mohamed, Morteza Salehjahromi, Sheeba J Sujit, Yuliya Kitsel, Steven H Lin, Zhongxing Liao, Saumil Gandhi, David Qian, David Jaffray, Caroline Chung, Natalie I Vokes, Jianjun Zhang, J Jack Lee, John V Heymach, Jia Wu, Joe Y Chang
Faculty, Staff and Student Publications
Background: The recent phase II randomized stereotactic ablative radiotherapy with and without immunotherapy (I-SABR) trial has shown improved event-free survival (EFS) when adding immunotherapy to stereotactic ablative radiotherapy (SABR) for early-stage inoperable non-small cell lung cancer (NSCLC). However, optimizing patient selection thereof is critical, because not every patient benefits from immunotherapy. Leveraging the powerful use of artificial intelligence, this secondary analysis of the I-SABR trial developed a modeling system (named "I-SABR-SELECT") based on clinical and radiomic factors to address which patients should receive additional immunotherapy.
Methods: The discovery/validation cohorts were from the I-SABR trial, with external validation from the single-arm …
Bridging The Gap: Awareness Of Healthy Menstrual Practices Among Married And Single Women In Baghdad Teaching Hospital: A Cross-Sectional Study, Ban Yousif Yaaqoob
Bridging The Gap: Awareness Of Healthy Menstrual Practices Among Married And Single Women In Baghdad Teaching Hospital: A Cross-Sectional Study, Ban Yousif Yaaqoob
Al-Nisour Journal for Medical Sciences
Background: Menstruation is a natural biological process that significantly impacts women’s physical and emotional well-being. Despite its universality, misconceptions and unhealthy practices surrounding menstruation persist, particularly in low- and middle-income countries (LMICs). This study aimed to assess the knowledge and practices of married and single women regarding healthy menstrual habits in Baghdad, Iraq.
Methods: A cross-sectional study was conducted from December 20, 2022, to February 25, 2023, involving 100 women divided into two groups: 50 single females from the College of Health and Medical Techniques and 50 married employees from Baghdad Teaching Hospital. Data were collected through structured interviews and …
Enhancing Automated Lung Disease Detection From Chest Radiography: An Interpretable Deep Learning Approach With Integrated Preprocessing And Ensemble Modeling, Ahmed Mohammed Abdulkarem, Jamal Kamil K. Abbas, Qamar Ali Abdulridha
Enhancing Automated Lung Disease Detection From Chest Radiography: An Interpretable Deep Learning Approach With Integrated Preprocessing And Ensemble Modeling, Ahmed Mohammed Abdulkarem, Jamal Kamil K. Abbas, Qamar Ali Abdulridha
Al-Nisour Journal for Medical Sciences
In this study, we tackled the problem of early pulmonary disease detection in chest radiography by developing and evaluating a sophisticated deep learning framework. Our goal was to improve diagnostic precision for conditions like cancer and pneumonia. To do this, we combined insights from current literature with a rigorous experimental protocol using a 5,000-image sample from the well-known NIH Chest X-ray dataset. A core component of our work was the implementation of a multi-stage preprocessing pipeline, featuring both lung segmentation and targeted contrast enhancement, designed to focus the model’s attention on relevant clinical features.
We assessed our models, which were …
Assessment Of Some Cardiac Markers (Ck-Mb, Myoglobin And Troponin) In Iraqi Type-2 Diabetic Patients With Metabolic Syndrome, Hayder Bassim Najeb
Assessment Of Some Cardiac Markers (Ck-Mb, Myoglobin And Troponin) In Iraqi Type-2 Diabetic Patients With Metabolic Syndrome, Hayder Bassim Najeb
Al-Nisour Journal for Medical Sciences
Cardiovascular diseases in the context of diabetes represent a main cause of morbidity and mortality with a two to three times higher risk of cardiovascular diseases in T2DM patients than in people without the condition (normoglycemia). The current study aimed to assess some Cardiac markers (CK-MB, myoglobin and troponin) in Iraqi type two diabetic patients with metabolic syndrome. The study was carried out on (60) patients with type-2 Diabetes mellitus who were divided into 2 groups: (30) subjects having metabolic syndromes and (30) subjects without metabolic syndromes. Venous blood samples were taken from patients who visited the Medical City Hospital-Baghdad …
The Impact Of Storage Duration And Elevated Temperature On The Biological And Chemical Characteristics Of Whole Milk Powder, Hussein Ali Shaghati, Rawia Mahmood Yousif, Asmaa Ali Awad
The Impact Of Storage Duration And Elevated Temperature On The Biological And Chemical Characteristics Of Whole Milk Powder, Hussein Ali Shaghati, Rawia Mahmood Yousif, Asmaa Ali Awad
Al-Nisour Journal for Medical Sciences
A total of 45 Whole milk powder(WMP) samples from the same brand and batch were collected and tested pre and post-storage under closed conditions at 45–50 °C. during 60, 90, 120, and 150-day intervals. For the chemical indicators of the WMP, there were no significant differences in the content of fat during the different storage intervals, as the fat value was 30.00–29.99%, while the protein percent was 23.23% and did not change significantly during the storage at 60, 90, 120, and 150 days respectively. On the other hand, significant differences occurred in the moisture content, where the moisture value ranged …
Nanoseal-X: A Theoretical Design For A Phase-Aligned Multifunctional Wound Dressing Based On Chitosan–Ha–Nanoparticle Composite, Mohammed Mahdi Salman Ghadban
Nanoseal-X: A Theoretical Design For A Phase-Aligned Multifunctional Wound Dressing Based On Chitosan–Ha–Nanoparticle Composite, Mohammed Mahdi Salman Ghadban
Al-Nisour Journal for Medical Sciences
Chronic wounds pose major clinical and economic challenges, especially in patients with comorbidities or impaired healing responses. This study presents NanoSeal-X™, a bioinspired multifunctional wound dressing engineered to address distinct biological demands at each phase of healing. The theoretical construct integrates a dual-layer matrix: a hyaluronic acid-based hydrogel embedded with silver nanoparticles, amoxicillin, and lidocaine, supported by a chitosan-based scaffold. Each component is strategically selected to provide hemostasis, infection control, tissue regeneration, and pain relief. This work presents a theoretical design framework to guide the development of multifunctional wound dressings. NanoSeal-X™ integrates pharmacological and bioactive components aligned with distinct healing …
Shohani Hormonal Guard (Shg): A Multifunctional Nutraceutical Approach To Treating Polycystic Ovary Syndrome Through Metabolic, Hormonal, And Anti-Inflammatory Pathways, Mohammed Mahdi Salman Ghadban
Shohani Hormonal Guard (Shg): A Multifunctional Nutraceutical Approach To Treating Polycystic Ovary Syndrome Through Metabolic, Hormonal, And Anti-Inflammatory Pathways, Mohammed Mahdi Salman Ghadban
Al-Nisour Journal for Medical Sciences
Polycystic Ovary Syndrome (PCOS) is a complex endocrine-metabolic disorder affecting women of reproductive age. It is characterized by ovarian dysfunction, insulin resistance, and hyperandrogenism, often accompanied by an overactive hypothalamic-pituitary-adrenal (HPA) axis. “Shohani Hormonal Guard” (SHG) is a nutraceutical formulation designed to target PCOS pathophysiology via multiple ingredients. We present a comprehensive review of SHG’s components – including inositols, N-acetylcysteine (NAC), berberine, ashwagandha, omega-3 fatty acids, and micronutrients (zinc, magnesium, vitamin B6, vitamin D3/K2, resveratrol, chromium, probiotics, etc.) – and their mechanistic roles and clinical benefits in PCOS. The literature demonstrates that SHG’s ingredients improve insulin sensitivity, modulate cortisol and …
Correlation Of Immunological Biomarkers And Severity Of Pneumonia In Pediatric Patients, Dhifaf Abdulrhaman, Mohammed B Hassan
Correlation Of Immunological Biomarkers And Severity Of Pneumonia In Pediatric Patients, Dhifaf Abdulrhaman, Mohammed B Hassan
Al-Nisour Journal for Medical Sciences
Among children under five, pneumonia stands as a major contributor to both illness and death, creating a significant challenge for global health efforts. This study aimed to evaluate the correlation between radiological severity, clinical parameters (such as fever and oxygen saturation), and laboratory markers (including CRP levels, white blood cell count, and the neutrophil-to-lymphocyte ratio) in pediatric patients with pneumonia. A retrospective analysis was conducted on 51 hospitalized children with severe pneumonia admitted to Al Mansour Pediatric Hospital in Baghdad from July 2024 to February 2025. The results revealed a strong association between radiologic severity and clinical indicators, with higher …
The Role Of Regulatory T Cells In Ischemic Heart Disease Patients, Duha Alaa Hassan, Hayfaa Mahmood Fahad, Saad Fadhel Nassar
The Role Of Regulatory T Cells In Ischemic Heart Disease Patients, Duha Alaa Hassan, Hayfaa Mahmood Fahad, Saad Fadhel Nassar
Al-Nisour Journal for Medical Sciences
Background: Regulatory T cells (Tregs) represent 5–10% of the total T cell population and are known as potent suppressors of the immune system. They are crucial for managing immune activation, ensuring peripheral tolerance, and supporting tissue repair and overall homeostasis. These cells are characterized by the expression of specific biomarkers, including CD4+, FOXP3+, and CD25+. While CD4 and CD25 were initially used for their identification, the discovery of CD25 on other T cell types led to a more precise evaluation of Tregs through the assessment of the intracellular Foxp3 transcription factor.
Objective: The primary goal of this study was to …
Lived Experiences Of Obese Women In Mississippi Concerning The Role Of Psychosocial Factors In The Development Of Obesity, Temitope Olabode
Lived Experiences Of Obese Women In Mississippi Concerning The Role Of Psychosocial Factors In The Development Of Obesity, Temitope Olabode
Walden Dissertations and Doctoral Studies
One of the highest rates of obesity in the United States is in Mississippi, where middle- aged obese women deal with a variety of social, cultural, and personal issues, including shame, discrimination, and stigma based on weight, mental anguish, cultural norms, financial limitations, and restricted access to healthcare. This study investigated the psychosocial factors that contribute to obesity in women aged 40- 60 years, and the effects of obesity on body image, self-esteem, health behaviors, and quality of life. A qualitative phenomenological study using the social ecological model (SEM) framework looked at the individual, interpersonal, and policy levels of the …
Alternative And Traditional Schooling On Sexual Risk Behaviors Among Alaska Native Youth In The Lower Kuskokwim, Nathaniel Hebert
Alternative And Traditional Schooling On Sexual Risk Behaviors Among Alaska Native Youth In The Lower Kuskokwim, Nathaniel Hebert
Walden Dissertations and Doctoral Studies
Alaska Native youth experience disproportionately high rates of sexual risk, yet disaggregated data and school-contextual analyses remain limited. Understanding how school type (alternative vs. traditional) and individual factors influence sexual risk among Alaska Native youth is essential for informing targeted, culturally responsive health interventions and addressing ongoing health disparities. This quantitative study aimed to examine the association between three behaviors (condom use, multiple sexual partners, and substance use) by school type, controlling for gender, grade level, body mass index, and afterschool activity. Guided by the social-ecological model, this cross-sectional study provided new insights into the relationship between school type and …
The Great Escape: A Case Series On Ddx3x Craniofacial Phenotypes In Females, Ellen Wang, Kylie Swiekatowski, Danielle Sobol, Matthew Greives, Emily Hansen-Kiss