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Brain Uptake, Retention, And Efflux Of Aluminum And Manganese, Robert A. Yokel

Pharmaceutical Sciences Faculty Publications

My colleagues and I investigated the sites and mechanisms of aluminum (Al) and manganese (Mn) distribution through the blood-brain barrier (BBB). Microdialysis was used to sample non-protein-bound Al in the extracellular fluid (ECF) of blood (plasma) and brain. Brain ECF Al appearance after intravenous Al citrate injection was too rapid to attribute to diffusion or to transferrin-receptor-mediated endocytosis, suggesting another carrier-mediated process. The brain:blood ECF Al concentration ratio was 0.15 at constant blood and brain ECF Al concentrations, suggesting carrier-mediated brain Al efflux. Pharmacological manipulations suggested the efflux carrier might be a monocarboxylate transporter (MCT). However, the lack of Al …

The Flame, Fall 2002, Mennonite College Of Nursing

The Flame (1985-present)

The Flame is a newsletter of Illinois State University's Mennonite College of Nursing

Effects Of Daily Oral Care With 0.12% Chlorhexidine Gluconate And A Standard Oral Care Protocol On The Development Of Nosocomial Pneumonia In Intubated Patients- A Pilot Study, Michelle Lynn Bopp

Dental Hygiene Theses & Dissertations

The initial purpose of the study was to determine if a difference existed between nosocomial pneumonia rates for intubated patients who received twice daily oral hygiene care with 0.12% chlorhexidine gluconate and those who received the standard oral care while in the critical care unit (CCU). Over seven months (February - August), participants were identified through screening and consent procedures, and randomized into one of two groups. Over the seven months, only five subjects were enrolled. While in the study, twice-daily oral hygiene care consisting of brushing the cheeks, teeth and endotracheal tube with a suctioning toothbrush using an FDA …

Consumer Health Information For Asians (Chia): A Collaborative Project, Deborah D. Halsted, Beatriz Varman, Marsha Sullivan, Lynne Nguyen

Library Staff Publications

According to the 2000 United States Census, the Asian population in Houston, Texas, has increased more than 67% in the last ten years. To supplement an already active consumer health information program, the staff of the Houston Academy of Medicine-Texas Medical Center Library worked with community partners to bring health information to predominantly Asian neighborhoods. Brochures on health topics of concern to the Asian community were translated and placed in eight informational kiosks in Asian centers such as temples and an Asian grocery store. A press conference and a ribbon cutting ceremony were held to debut the kiosks and to …

What's Happening: September 11, 2002, Maine Medical Center

What's Happening

No abstract provided.

Flexor Tendon Repair And Rehabilitation: State Of The Art In 2002, Martin I. Boyer, James W. Strickland, Drew R. Engles, Kavi Sachar, Fraser J. Leversedge

Open Access Publications

No abstract provided.

Ipr : Pharmaceuticals, Rupa Chanda

IIMB Management Review

In the introductory panel of the Conference on IPR, the speakers included S Chandrasekaran, Deputy Controller of Patents & Designs, Govt of India; M D Nair, Consultant to the Pharmaceutical Industry, Chennai; P P Prabhu, former Commerce Secretary, Government of India; K Raghavendra Rao, MD, Orchid Chemicals & Pharmaceuticals and Jayashree Watal, Consultant to the WTO Secretariat. S Chandrasekaran clarified what constitutes intellectual property, what a patent is, and how an invention may qualify for a patent.He pointed out that as a participant in the TRIPS Agreement, India is obliged to modify her statutes to make her IPR regime TRIPS …

Inside Unlv, Diane Russell

Inside UNLV

No abstract provided.

Update - September 2002, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Just Put Me to Sleep . . . PLEASE!: Ethical Issues in Palliative and "Terminal" Sedation
-- Terminal Sedation: A Jewish Perspective
-- Terminal Sedation: A Catholic Perspective
-- Announcing the Center for Christian Bioethics Nation Conference in 2003: "Promise and Peril of the New Genetics"
-- Center news . . .

Jefferson Alumni Bulletin – Volume 51, Number 4, September 2002

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 51, Number 4, September 2002 Dean's Message by Dean Thomas J. Nasca ’75, page 4 Achievement Award Winner Charles Francis ’65, page 6 Jim Bagian ’77 Receives an Honorary Doctorate, page 7 Reunions and Annual Giving, page 12 Class notes attached as supplemental file.

Comparative Study--Efficacy, Safety And Compliance Of Intravenous Iron Sucrose And Intramuscular Iron Sorbitol In Iron Deficiency Anemia Of Pregnancy, A Wali, A Mushtaq, Nilofer

Department of Obstetrics & Gynaecology

Objective: (1) To determine an alternative iron supplementation with better efficacy, compliance & safety in treatment of iron deficiency anemia during pregnancy, (2) to reduce blood transfusion during pregnancy, labor and puerperium.
Material and Method: A prospective comparative study. A total number of 60 pregnant women with the gestational age of 12 - 34 weeks were included in the study who were suffering from iron deficiency anemia. They were divided in 3 groups (A, B and C). Group A (n15) received intravenous iron sucrose according to recommended dose containing 500 mg of iron sucrose for storage, in group B (n=20) …

What's Happening: August 28, 2002, Maine Medical Center

What's Happening

No abstract provided.

Ada News - 08/05/2002, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Information Interface - Volume 30, Issue 4 - August/September 2002, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

Nuclear Transformation Of Chlamydomonas Reinhardtii To Allow For Studies On Circadian Expression Of The Β-Tubulin Gene, Mohammed Khan

Masters Theses & Specialist Projects

Circadian rhythms are rhythms that are capable of free-running in constant conditions with a period of approximately 24 hours, that are able to compensate temperature effects on their periods, and that have the ability to entrain to daily light-dark and/or temperature cycle. In order to explore the circadian output pathway that regulates β-tubulin gene expression in Chlamydomonas reinhardtii, a nuclear transformation of the organism was performed with a β-tubulin promoter:reporter gene construct. To increase the efficiency of the selection, a cotransformation procedure was adapted with ble, an antibiotic resistance gene. To achieve maximum transformation efficiency, a cell wall-less mutant of …

The Relationship Of Demographic Characteristics To Consumer Knowledge Of Diet And Health Relationships To Intake Of Soy Foods And Soy Supplements, Ashlyn K. Hosokawa

All-Inclusive List of Electronic Theses and Dissertations

In 1999, the FDA approved a health claim for a relationship between intake of 25 grams of soy protein per day and reduced risk of heart disease. Literature suggests that consumers are increasingly krtowledgeable about diet and disease risk factors. While gender, age, race, and family history cannot be altered, diet may be changed to decrease risks. This study explored the relationship of demographic characteristics to consumer knowledge and use of some of the more popular soy products and supplements. Surveys were completed by a random sample of 100 attendees at area festivals and 100 nutrition professionals at a national …

Family Nurse Practitioners' Perceptions Of Bereavement Care, Joy Young Loden

MSN Research Projects

Studies have shown that long-term effects of bereavement increase health problems among many individuals. There is an increased need for bereavement care among family nurse practitioners to lessen physical and mental anguish among those who have experienced a loss. The purpose of this study was to describe and explore family nurse practitioners' perceptions of bereavement care. This study's importance was to find out what is being done to address patients' bereavement issues by the family nurse practitioner. Orlando's Nursing Process Theory was the theoretical framework that guided this study. The research question for this study was as follows : What …

Plagiocephaly: Developmental And Medical Outcomes, José Leonardo Fuentes

Loma Linda University Electronic Theses, Dissertations & Projects

Plagiocephaly, a condition that is observed by deformation of the head, comes as the result of different etiologies. The most serious involving premature fusion of one or more of the cranial sutures, a condition referred to as craniosynostosis. While children with craniosynostosis may be considered for developmental screening to determine whether they fall at risk for developmental delay, children with plagiocephaly are typically not seen as being at risk, their condition typically treated as a cosmetic problem. This study consisted of 85 children, 37 with plagiocephaly, 9 with craniosynostosis, and 39 nonclinical subjects. Results of this study suggest that children …

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 2002), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 2002 Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Opening Remarks
• PCOM Updates
• Alumnus Marks 100th Birthday
• Cover Story: College Moves Forward with Strategic Plan
• Aging and the Immune Response
• Class Notes
• In Memoriam
• My Turn
• 2003 Annual Fund
• PCOM Events

Optimisation Of Bile Production During Normothermic Preservation Of Porcine Livers., Charles J. Imber, Shawn D. St Peter, Inigo Lopez De Cenarruzabeitia, Hugh Lemonde, Mike Rees, Andrew Butler, Peter T. Clayton, Peter J. Friend

Manuscripts, Articles, Book Chapters and Other Papers

Machine perfusion of livers may provide a mechanism for extended preservation of marginal donor organs before transplantation, as well as a method for viability assessment. It has proved possible in a series of experimental porcine liver perfusions to maintain liver viability for up to 72 h. However, a reduction in bile production with associated histological evidence of cholestasis was seen after 10 h of perfusion, damaging the biliary canaliculi during the preservation period and leaving these organs in an unacceptable condition for transplantation. It was proposed that reduction in bile production was the result of a relentless depletion of available …

The Relationship Between Perceived Self-Efficacy, Regimen Adherence, And Glycemic Control In Adolescents With Type 1 Diabetes Mellitus: A Pilot Study, Antonieta Pelias Alteza

Theses and Dissertations - UTB/UTPA

This pilot study examined the relationship between perceived self-efficacy and regimen adherence on glycemic control among adolescents, aged 11 to 18 years, with Type 1 Diabetes Mellitus. Thirty-six adolescent-parent dyads participated in this study. Bivariate analysis using Pearson product moment-correlations identified no significant relationships among the variables. Regarding treatment regimen, adolescents on insulin pumps had a mean glycosylated hemoglobin level of 8.09% whereas adolescents on daily insulin injections had a mean glycosylated hemoglobin level of 9.26%. Bandura's theory of self-efficacy provided the theoretical framework for this study. The Self-Efficacy for Diabetes scale and Questionnaire of Self-Care Behaviors scale were used …

Regulation Of Retinoic Acid Receptor Α By Protein Kinase C In B16 Mouse Melanoma Cells, Goran Boskovic, Dinakar Desai, Richard M. Niles

Biochemistry and Microbiology

We have previously found that retinoic acid stimulates the expression of protein kinase Cα (PKC) in B16 mouse melanoma cells. Because it has been reported that PKC can phosphorylate retinoic acid receptor (RAR) and alter its function, we determined whether changes in the level and/or activity of PKC could affect the expression or function of the RAR in B16 melanoma. Using in vivophosphorylation and band shift techniques, we could not demonstrate that altering PKC activity and/or protein level changed thein vivo phosphorylation of RARα. However activation of PKC resulted in increased RARα protein. Increased receptor protein correlated with …

Role Of Lipid Peroxidation And Antioxidant Enzymes In Omega 3 Fatty Acids Induced Suppression Of Breast Cancer Xenograft Growth In Mice, W. Elaine Hardman, Jesus Munoz Jr., Ivan L. Cameron

Biochemistry and Microbiology

Background:

Supplementing mice with high levels of dietary n-3 polyunsaturated fatty acids (PUFAs) increases the n-3 PUFAs in cell membranes, increases the susceptibility of the cells for lipid peroxidation (LPO) and decreases the growth rate of mammary and other tumors. However, the results of an earlier study indicated that a factor in addition to LPO was involved in the reduction in tumor growth in n-3 PUFAs fed mice. Athymic mice bearing MDA-MB-231 human breast carcinoma xenografts, were fed fish oil concentrate (FOC) or control diets, with and without supplemental Vitamin E (2000 IU /kg diet) and were sacrificed both before …

What's Happening: July 17, 2002, Maine Medical Center

What's Happening

No abstract provided.

Aha Guidelines For Primary Prevention Of Cardiovascular Disease And Stroke: 2002 Update - Consensus Panel Guide To Comprehensive Risk Reduction For Adult Patients Without Coronary Or Other Atherosclerotic Vascular Diseases, Thomas A. Pearson, Steven N. Blair, Stephen R. Daniels, Robert H. Eckel, Joan M. Fair, Stephen F. Fortmann, Barry A. Franklin, Larry B. Goldstein, Philip Greenland, Scott M. Grundy, Yuling Hong, Nancy Houston-Miller, Ronald M. Lauer, Ira S. Ockene, Ralph L. Sacco, James F. Sallis, Sidney C. Smith Jr., Neil J. Stone, Kathryn A. Taubert

Faculty Publications

No abstract provided.

What's Happening: July 3, 2002, Maine Medical Center

What's Happening

No abstract provided.

Healthnet News V.17:No.2 Summer 2002, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.

Jefferson Medical College Annual Report, 2002, Thomas J. Nasca

Jefferson Medical College Administrative Documents and Reports

No abstract provided.

Challenges, Strategies, And Tools For Research Scientists: Using Web-Based Information Resources, Danielle Bodrero Hoggan

E-JASL: Electronic Journal of Academic and Special Librarianship (1999-2009, Volumes 1-10)

Scientists face many challenges in harnessing web-based resources. Information overload, misinformation, fees, poorly designed navigation, and loss of browsability all hamper the scientist searcher. In addition, many scientists rely on only one or two databases and often miss unique information that is available through other sources. Librarians can team up with scientists to develop strategies to overcome the challenges of web-based information. For example, a librarian can teach effective information seeking techniques, including how to use controlled vocabularies, how to evaluate information on the web, and how to complement web-based resources with print resources. Librarians can also help scientists to …

In-Home Prenatal Nutrition Intervention Increased Dietary Iron Intakes And Reduced Low Birthweight In Low-Income African-American Women, Chiquita Briley, Nicole L. Flanagan, Nancy M. Lewis

Department of Nutrition and Health Sciences: Faculty Publications

Low birthweight (LBW), defined as an infant weighing less than 2,500 grams (1), is a major determinant of infant mortality and contributes to infant and childhood morbidity and increased healthcare costs (2-4). LBW occurs due to preterm delivery (length of gestation less than 37 weeks), growth retardation, or both (2). In the United States, higher rates of LBW occur in urban areas with high concentrations of low-income ethnic minorities (5). Results of the 1997 Pediatric Nutrition Surveillance indicate that the rate of LBW in the United States was 13% for African-American infants, and 8% for whites (6). Healthy People 2010 …