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The Ecological Ramifications Of Disease And Density In The Caribbean Spiny Lobster, Panulirus Argus, Donald C. Behringer Jr. Apr 2003

The Ecological Ramifications Of Disease And Density In The Caribbean Spiny Lobster, Panulirus Argus, Donald C. Behringer Jr.

Biological Sciences Theses & Dissertations

In 1999, I discovered the first virus known to be pathogenic to any species of lobster. HLV-PA is a pathogenic herpes-like virus that infects juvenile Caribbean spiny lobster, Panulirus argus, in the waters off south Florida (USA), and it alters the behavior and ecology of this species in fundamental ways. Gross signs of HLV-PA infection are lethargy, morbidity, cessation of molting, and discolored, “milky” hemolymph that does not clot. HLV-PA infects the hemocytes of host lobsters, specifically the hyalinocytes and semi-granulocytes, but not the granulocytes. When hemolymph from infected donors was injected into healthy juvenile lobsters, 90% of the …


The Glycemic Index, Pauline Williams, Wendy Stubbs Apr 2003

The Glycemic Index, Pauline Williams, Wendy Stubbs

All Current Publications

The glycemic index is a ranking of carbohydrate containing foods. Foods are ranked according to their immediate effect on blood sugar levels. The higher a food raises blood sugar, the higher its glycemic index


High Dietary Level Of Synthetic Vitamin E On Lipid Peroxidation, Membrane Fatty Acid Composition And Cytotoxicity In Breast Cancer Xenograft And In Mouse Host Tissue, Ivan L. Cameron, Jesus Munoz, Christopher J. Barnes, W. Elaine Hardman Mar 2003

High Dietary Level Of Synthetic Vitamin E On Lipid Peroxidation, Membrane Fatty Acid Composition And Cytotoxicity In Breast Cancer Xenograft And In Mouse Host Tissue, Ivan L. Cameron, Jesus Munoz, Christopher J. Barnes, W. Elaine Hardman

Biochemistry and Microbiology

Background

d-α-tocopherol is a naturally occurring form of vitamin E not previously known to have antitumor activity. Synthetic vitamin E (sE) is a commonly used dietary supplement consisting of a mixture of d-α-tocopherol and 7 equimolar stereoisomers. To test for antilipid peroxidation and for antitumor activity of sE supplementation, two groups of nude mice bearing a MDA-MB 231 human breast cancer tumor were fed an AIN-76 diet, one with and one without an additional 2000 IU/kg dry food (equivalent to 900 mg of all-rac-α-tocopherol or sE). This provided an intake of about 200 mg/kg body weight per day. The mice …


Pregnancy, Drug Testing, And The Fourth Amendment: Legal And Behavioral Implications, Brian H. Bornstein Mar 2003

Pregnancy, Drug Testing, And The Fourth Amendment: Legal And Behavioral Implications, Brian H. Bornstein

Department of Psychology: Faculty Publications

In its efforts to protect the health of unborn children, the government is increasingly attempting to regulate pregnant women’s conduct. As with other policies affecting pregnant women’s autonomy, these policies have constitutional overtones. In Ferguson v. City of Charleston (2001), the Supreme Court struck down a South Carolina hospital’s policy of testing pregnant women for cocaine and turning positive results over to law enforcement for prosecution. This article discusses the basis of the decision and its legal and behavioral implications. Although the decision came down on the side of pregnant women’s rights, it left unresolved the issue of whether a …


A Cost-Effectiveness Analysis Of A Community-Based Health Promotion Intervention For Adults With Mobility Impairments: Living Well With A Disability, Craig Ravesloot Ph.D., Tom Seekins Ph.D., Catherine Ipsen M.A., Steve Seninger Ph.D., Colleen Murphy-Southwick Ph.D., Lisa Brennan M.L.S., Rita K. Fjeld M.A., Glen W. White Ph.D., Ann Branstetter Ph.D., Vivian Chapman M.A., Amanda Jay M.A., James A. Bovaird M.A., Janet Marquis Ph.D., University Of Montana Rural Institute Mar 2003

A Cost-Effectiveness Analysis Of A Community-Based Health Promotion Intervention For Adults With Mobility Impairments: Living Well With A Disability, Craig Ravesloot Ph.D., Tom Seekins Ph.D., Catherine Ipsen M.A., Steve Seninger Ph.D., Colleen Murphy-Southwick Ph.D., Lisa Brennan M.L.S., Rita K. Fjeld M.A., Glen W. White Ph.D., Ann Branstetter Ph.D., Vivian Chapman M.A., Amanda Jay M.A., James A. Bovaird M.A., Janet Marquis Ph.D., University Of Montana Rural Institute

Health and Wellness

This document reports on research conducted by the University of Montana and the University of Kansas for the Office of Disability and Health at the Centers for Disease Control and Prevention. The research project, conducted between August 1,1997 and July 31, 2001, was conducted in four separate but related studies. The research was conducted in eight States. We contracted with nine centers for independent living (CIL) to conduct 34 Living Well with a Disability health promotion workshops and to collect outcome measures. These programs included 246 individuals. In the first study, we evaluated the effectiveness and cost outcomes of the …


Flight Physician - March, 2003, Civil Aviation Medical Association Mar 2003

Flight Physician - March, 2003, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A twenty page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


What's Happening: March, 2003, Maine Medical Center Mar 2003

What's Happening: March, 2003, Maine Medical Center

What's Happening

No abstract provided.


"Are You Beginning To See A Pattern Here?" Family And Medical Discourses Shape The Story Of Black Infant Mortality, Elaine R. Cleeton Mar 2003

"Are You Beginning To See A Pattern Here?" Family And Medical Discourses Shape The Story Of Black Infant Mortality, Elaine R. Cleeton

The Journal of Sociology & Social Welfare

Postmodern and poststructuralist theorizations of the interrelations of the particular and the universal have identified women's bodies to be the last frontier for scientific discovery leading to and satisfying the modern compulsion to stabilize and control life from birth to death. This institutional ethnography of one city's response to an elevated infant mortality rate among the babies of African American urban, impoverished women explores their discursive transformation from single mothers who cannot begin prenatal care before the second trimester because too few physicians will treat Medicaid patients, into sexually-immoral, illegaldrug- using women who deliberately harm their babies. The study locates …


A Child's Death: Lessons From Health Care Providers' Texts, Nancy M. Bell, Marie L. Campbell Mar 2003

A Child's Death: Lessons From Health Care Providers' Texts, Nancy M. Bell, Marie L. Campbell

The Journal of Sociology & Social Welfare

This article originates from a research study that explores 'what happened' to a 10-year-old child with Rett syndrome, who died from "severe malnutrition" according to a Coroners Service inquest jury. The inquest evidence analyzed, using institutional ethnography, shows that approximately one week prior to this child's death three health care providers (an emergency physician, a hospice volunteer and a home care nurse) conducted individual assessments of the child. Child protection workers were also involved. Textual analysis of the health care providers' records shows how the child was officially and textually constructed as 'dying from a terminal illness' in contrast to …


Oncolog, Volume 48, Number 03, March 2003, David Galloway, Ann Sutton, Katie Prout Matias, Donna R. Copeland Phd Mar 2003

Oncolog, Volume 48, Number 03, March 2003, David Galloway, Ann Sutton, Katie Prout Matias, Donna R. Copeland Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

  • Pediatric Oncologists Search for More Effective Drugs to Treat an ‘Orphan Disease’
  • Collaborative Studies Lead to Better Survival Rates in Young Patients with Rhabdomyosarcoma
  • Protecting the Heart and Gastrointestinal Tract from Treatment-Associated Damage Is an Important Element of Cancer Care
  • House Call: Conquering the Pain of Cancer
  • DiaLog: Recognizing and Treating Cognitive Dysfunctions in Survivors of Childhood Cancers, by Donna R. Copeland, PhD, Professor, Department of Pediatrics


Effect Of Ca(Oh)2 On Survival Ability Of A Bacterial Mixture: An In Vitro Study, Nishan Antranik Odabashian Mar 2003

Effect Of Ca(Oh)2 On Survival Ability Of A Bacterial Mixture: An In Vitro Study, Nishan Antranik Odabashian

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this in vitro investigation was to evaluate the antibacterial effect of calcium hydroxide on a mixture of nine bacteria associated with endodontic infections at different time intervals and to examine the survival of the same bacteria when in mixture. A total of 102 teeth were used in the first part of the experiment. Eighty teeth were used in eight experimental groups of 10 each, 16 teeth were used for positive and negative controls, and six teeth were used for scanning electron microscopy (SEM). Nine species of bacteria were used in both experiments. These consisted of Enterococcus faecalis, …


Jefferson Alumni Bulletin – Volume 52, Number 2, March 2003 Mar 2003

Jefferson Alumni Bulletin – Volume 52, Number 2, March 2003

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 52, Number 2, March 2003 Dean's Column by Dean Thomas J. Nasca ’75, page 4 Ushering in the Modern Era in Surgery: the Heart-Lung Machine, Developed Here, 50 Years Ago, page 8 One of the "Seven Greatest Doctors in America", page 9 Pulmonary/Critical Care Fellows Win National Competition, Besting 88 Other Medical Schools, page 10 Two Medical Students Win AOA National Awards , page 11 Laparoscopic Radical Prostatectomy Is First in the Delaware Valley, page 12 Jefferson Surgeons Perform Philadelphia’s First Incompatible Kidney Transplant, page 12 Chinese Health Information Center Receives $1.5 Million to Expand, …


In Utero Indomethacin Alters O₂ [Oxygen] Delivery To The Fetal Ductus Arteriosus : Implications For Persistent Postnatal Patency, Seth Hamlin Goldbarg Feb 2003

In Utero Indomethacin Alters O₂ [Oxygen] Delivery To The Fetal Ductus Arteriosus : Implications For Persistent Postnatal Patency, Seth Hamlin Goldbarg

Yale Medicine Thesis Digital Library

Exposure of the fetus to indomethacin produces constriction of the fetal ductus arteriosus (DA) and hypoxia in the avascular muscle media of the vessel wall. Hypoxia induces cell death, which increases the incidence of patent DA in the newborn period. We used a fetal sheep model to determine the factors that were responsible for indomethacin-induced hypoxia at various degrees of DA constriction. Indomethacin produced DA constriction in all fetuses studied in vivo. Cell death in the DA wall was directly related to the degree of indomethacin-induced DA constriction and was present at both moderate (pressure gradient across DA <16 >mmHg) and …


Ada News - 02/03/2003, American Dental Association, Publishing Division Feb 2003

Ada News - 02/03/2003, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.


Estradiol Effects On The Growth Hormone/Insulin-Like Growth Factor-1 Axis In Amenorrheic Athletes, Debra L. Waters, Richard I. Dorin, Clifford R. Qualls, Brent Ruby, Richard N. Baumgartner, Robert A. Robergs Feb 2003

Estradiol Effects On The Growth Hormone/Insulin-Like Growth Factor-1 Axis In Amenorrheic Athletes, Debra L. Waters, Richard I. Dorin, Clifford R. Qualls, Brent Ruby, Richard N. Baumgartner, Robert A. Robergs

Integrative Physiology and Athletic Training Faculty Publications

Disruption of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis has been reported and studied in menopause, hypothalamic amenorrhea, and anorexia nervosa, but not in weight-stable amenorrheic athletes. We investigated the effects of short-term transdermal estradiol on basal and exercise-stimulated serum GH, IGF-1, and associated binding proteins (IGFBP-1 and IGFBP-3) in seven weight-stable female amenorrheic athletes with percentage body fats greater that 12%. Each subject received a 72h placebo patch followed by 144h of transdermal estradiol. Serum samples for GH, IGF-1, IGFBP-1, and IGFBP-3 were obtained at baseline (t1), 72hr (0), 144hr (6), and during three 90-minute trials of aerobic exercise. …


Escape From New York: Analyzing The State's Relative Interests In Proscribing The Withdrawal Of Life Support And Physician-Assisted Suicide, Colin Miller Feb 2003

Escape From New York: Analyzing The State's Relative Interests In Proscribing The Withdrawal Of Life Support And Physician-Assisted Suicide, Colin Miller

William & Mary Bill of Rights Journal

This Note argues that states cannot consistently prohibit physician assisted suicide for terminally ill patients while they continue to allow the withdrawal of life support for even non-terminal patients. All of the state interests identified by the Supreme Court in rejecting a right to assisted suicide are implicated to a higher degree by withdrawal of life support. The primary reason for this difference is that withdrawal of life support often involves incompetent patients and surrogate decision making while assisted suicide by definition requires a competent patient choosing to hasten her death


Hiv Protease Inhibitors Promote Atherosclerotic Lesion Formation Independent Of Dyslipidemia By Increasing Cd36-Dependent Cholesteryl Ester Accumulation In Macrophages, James Dressman, Jeanie Kincer, Sergey V. Matveev, Ling Guo, Richard N. Greenberg, Theresa Guerin, David Meade, Xiang-An Li, Weifei Zhu, Annette M. Uittenbogaard, Melinda E. Wilson, Eric J. Smart Feb 2003

Hiv Protease Inhibitors Promote Atherosclerotic Lesion Formation Independent Of Dyslipidemia By Increasing Cd36-Dependent Cholesteryl Ester Accumulation In Macrophages, James Dressman, Jeanie Kincer, Sergey V. Matveev, Ling Guo, Richard N. Greenberg, Theresa Guerin, David Meade, Xiang-An Li, Weifei Zhu, Annette M. Uittenbogaard, Melinda E. Wilson, Eric J. Smart

Physiology Faculty Publications

Protease inhibitors decrease the viral load in HIV patients, however the patients develop hypertriglyceridemia, hypercholesterolemia, and atherosclerosis. It has been assumed that protease inhibitor–dependent increases in atherosclerosis are secondary to the dyslipidemia. Incubation of THP-1 cells or human PBMCs with protease inhibitors caused upregulation of CD36 and the accumulation of cholesteryl esters. The use of CD36-blocking antibodies, a CD36 morpholino, and monocytes isolated from CD36 null mice demonstrated that protease inhibitor–induced increases in cholesteryl esters were dependent on CD36 upregulation. These data led to the hypothesis that protease inhibitors induce foam cell formation and consequently atherosclerosis by upregulating CD36 and …


Utilization Of Algal And Bacterial Extracellular Polymeric Secretions (Eps) By The Deposit-Feeding Brittlestar Amphipholis Gracillima (Echinodermata), D. L. Hoskins, S. E. Stancyk, Alan W. Decho Feb 2003

Utilization Of Algal And Bacterial Extracellular Polymeric Secretions (Eps) By The Deposit-Feeding Brittlestar Amphipholis Gracillima (Echinodermata), D. L. Hoskins, S. E. Stancyk, Alan W. Decho

Faculty Publications

Like many deposit-feeding organisms, the burrowing brittlestar Amphipholis gracillima feeds on particulate organic matter in surface sediments. Microbial exopolymeric secretions (EPS) are carbohydrate-enriched polymers produced by microalgae and bacteria that bind aggregates and form dense biofilms near the sediment-water interface. EPS are assimilable by some benthic infauna and may be utilized as a significant carbon source. EPS are absorbed by some deposit-feeders, including a holothurian, and may be supplemental sources of nutrition. The burrowing brittlestar A. gracillima is a deposit-feeder that was used in a mass balance approach to model the incorporation of radiolabeled EPS by bottom feeders. Brittlestars were …


Radiologic Feeding Gastrostomy Placement: Experience In 23 Patients, T U. Haq, S M F Mosharraf, B Ahmad, K Munir, J Yaqoob, U Usman Feb 2003

Radiologic Feeding Gastrostomy Placement: Experience In 23 Patients, T U. Haq, S M F Mosharraf, B Ahmad, K Munir, J Yaqoob, U Usman

Department of Radiology

Objective: To evaluate the safety, efficacy and complications of percutaneous gastrostomy catheter placementunder flouro guidance for long-term enteral feeding.MATERIALS AND Methods: Between April 1998 to May 2002, 23 patients who had percutaneous gastrostomy catheter placement were retrospectively reviewed. Clinical indications for catheter placement included patients with neurologic disease, head and neck malignancy, and pulmonary disease patients. Placement of 12 - 14 Fr gastrostomy catheter was then accomplished with the Seldinger technique. The technical success, procedural complications were recorded.Results: Twenty seven procedures, including revisions, were performed. The success rate for catheter placement was 100%. Revision was necessary in 7 (30%) instances …


Stage Based Interventions For Low Fat Diet With Middle School Students, Marilyn Frenn, Shelly Malin, Naveen K. Bansal Feb 2003

Stage Based Interventions For Low Fat Diet With Middle School Students, Marilyn Frenn, Shelly Malin, Naveen K. Bansal

College of Nursing Faculty Research and Publications

Preventing obesity and cardiovascular disease at early ages is important; however, few effective interventions for early adolescents have been reported. In this study, low-income, culturally diverse students from an urban middle school (n = 60) received four classroom interventions with the use of a combined Health Promotion/Transtheoretical Model to control fat in diet and increase physical activity. A control group (n = 57) received the usual classroom education. Pretest percentage fat in diet was regressed on demographics, access to low-fat foods, perceived self-efficacy, benefits/barriers, and stage of change with results as proposed by the model [F(9,64) …


Healthnet News V.18:No.4 Winter 2003, Judith S. Kronick, Alberta Richetelle Jan 2003

Healthnet News V.18:No.4 Winter 2003, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.


Physical Wellness: The Relationship Between Motor Skill, Fitness And Physical Activity In Young Children, Beth P. Hands, Helen Parker Jan 2003

Physical Wellness: The Relationship Between Motor Skill, Fitness And Physical Activity In Young Children, Beth P. Hands, Helen Parker

Health Sciences Conference Papers

The health benefits of adequate physical activity levels for children are well reported. However, we cannot assume that children will choose to be sufficiently active of their own accord. Motor competence and fitness are increasingly highlighted as key co-determinants of physical activity in young children (Hands, Parker, & Larkin, 2001) and where possible strategies to enhance these factors should be included in early childhood settings. However few studies have adopted an integrated view of the collective effects of these three factors on developing healthy children. This presentation explores interrelationships between measures of motor skill competence, fitness, and weekly physical activity …


The Value Of Multidisciplinary Care In Parkinson's Disease, Miriam Hirsch, Mark Baron Jan 2003

The Value Of Multidisciplinary Care In Parkinson's Disease, Miriam Hirsch, Mark Baron

Case Studies from Age in Action

Educational Objectives

1. To recognize the signs and symptoms of Parkinson's disease (PD).

2. To identify key treatment and management strategies for PD.

3. To discuss the importance of multidisciplinary care and the need for individualized treatment of PD.


Current Trends In Athletic Training Education And Certification In Japan, Yuriko Ohashi Jan 2003

Current Trends In Athletic Training Education And Certification In Japan, Yuriko Ohashi

Theses, Dissertations and Capstones

Athletic trainer is a well-established profession in the U.S., but its definition is unclear in Japan because of no certification until recently. Japan Amateur Sports Association (JASA) has started in curriculum to prepare, educate and certify athletic trainers since 1994. This study researched the current trends in athletic training education and certification in Japan. It defines the historical and present athletic training situation, and clarifies education and certification with questionnaires. Questionnaires were sent to 43 sports medicine professors at JASA athletic trainer accredited and non-accredited program schools, and 26 (61%) responses were returned. The current problems include lack of clinical …


The Characterization Of Two Differentially Expressed Plasma Proteins In Obese Versus Lean Rats In Two Rodent Models Of Obesity, Roger D. Boggs Jan 2003

The Characterization Of Two Differentially Expressed Plasma Proteins In Obese Versus Lean Rats In Two Rodent Models Of Obesity, Roger D. Boggs

Theses, Dissertations and Capstones

Zucker fa and La/N faf rats are widely studied models of genetic obesity and its complications. These two rodent models of obesity were utilized to search for a circulating protein marker for obesity. Plasma samples from both of these models of obesity were collected and analyzed via SDS-PAGE analysis. Two proteins were found which demonstrate differential expression between lean and obese rats. Both proteins demonstrated increased expression in the obese rats compared to the lean. One differentially expressed protein migrated on SDS-PAGE gels at 116 KD while the second migrated at 22 KD compared to molecular weight markers. The 22 …


Expanding Self-Direction In Services For The Aged And People With Disabilities, Ruth A. Burgess Jan 2003

Expanding Self-Direction In Services For The Aged And People With Disabilities, Ruth A. Burgess

Theses, Dissertations and Capstones

Medicaid-funded long-term care services are traditionally delivered in nursing homes. States may apply for waivers which allow them to provide home and community based services with Medicaid funds. Because these services are by definition an alternative to nursing home care, waiver services are generally based upon a medical model which emphasizes medical deficits and tends to restrict consumers’ movements to inside the home. Recent developments such as the Olmstead Decision and federal New Freedom Initiatives have caused states to recognize that consumers desire and have a legal right to be part of a community rather than institutionalized or homebound. These …


Profile: University Of Minnesota School Of Public Health Around The World In 10 Minutes Jan 2003

Profile: University Of Minnesota School Of Public Health Around The World In 10 Minutes

International Journal of Global Health

What does the phrase "global health" mean to you? Does it mean doing HIV/AIDS education in Mysore? Working to improve air quality in Manila? Or marrying eastern and western health practices for the Hmong in Minneapolis? If you answered "all of the above," you're right. Global health is all this and more. At the University of Minnesota School of Public Health, we ascribe to the philosophy whereby public health challenges are exchanged equally between developed and developing countries, and together we share the responsibility for finding solutions to these challenges.


Increased Morbidity And Mortality In Single Parent Families: A Review, Katie Steneroden Jan 2003

Increased Morbidity And Mortality In Single Parent Families: A Review, Katie Steneroden

International Journal of Global Health

American families have changed dramatically in composition in recent decades. Increasing proportions of children are being raised in single parent households, reflecting both rising divorce rates, the growing percentage of births to unmarried women and adoption by single parents. As fewer children grow up in traditional families, there is increasing concern about the impact of alternative family structures on children's health and well-being. Many believe that there is a vital connection between family structure and youth well-being, with the nuclear family constituting the optimal structure for fostering "normal" development. Some say the change in the typical nuclear family is one …


The Educational Interaction Between Physical Therapy And Occupational Therapy Students, Kimberly K. Cleary, Dana M. Howell Jan 2003

The Educational Interaction Between Physical Therapy And Occupational Therapy Students, Kimberly K. Cleary, Dana M. Howell

Occupational Science and Occupational Therapy Faculty and Staff Research

The objectives of this study were to identify the prevalence of shared learning in U.S. physical therapy (PT) and occupational therapy (OT) education programs; determine what terminology is used for these courses; and identify perceived barriers, benefits, and challenges of the educational interactions. A survey, designed to collect information about the educational interaction between PT and OT students, was mailed to all program directors (n = 206) at each of the academic institutions (N = 103) in the United States with accredited or developing entry-level programs in PT and OT. A census study was conducted, and the entire study population …


Equilibrative Nucleoside Transporter Family Members From Leishmania Donovani Are Electrogenic Proton Symporters, Alex Stein, Gayatri Vaseduvan, Nicola S. Carter, Buddy Ullman, Scott M. Landfear, Michael Kavanaugh Jan 2003

Equilibrative Nucleoside Transporter Family Members From Leishmania Donovani Are Electrogenic Proton Symporters, Alex Stein, Gayatri Vaseduvan, Nicola S. Carter, Buddy Ullman, Scott M. Landfear, Michael Kavanaugh

Biomedical and Pharmaceutical Sciences Faculty Publications

Leishmania donovani express two members of the equilibrative nucleoside transporter family; LdNT1 encoded by two closely related and linked genes, LdNT1.1 and LdNT1.2, that transport adenosine and pyrimidine nucleosides and LdNT2 that transports inosine and guanosine exclusively. LdNT1.1, LdNT1.2, and LdNT2 have been expressed in Xenopus laevis oocytes and found to be electrogenic in the presence of nucleoside ligands for which they mediate transport. Further analysis revealed that ligand uptake and transport currents through LdNT1-type transporters are proton-dependent. In addition to the flux of protons that is coupled to the transport reaction, LdNT1 transporters mediate a variable constitutive proton …