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Articles 3601 - 3630 of 47817
Full-Text Articles in Entire DC Network
Factors Associated With The Severity Of Erythema Nodosum Leprosum Reactions, Ita Anggraini, Prima Kartika Esti, Eka Komarasari
Factors Associated With The Severity Of Erythema Nodosum Leprosum Reactions, Ita Anggraini, Prima Kartika Esti, Eka Komarasari
Journal of General - Procedural Dermatology and Venereology Indonesia
Background: Leprosy is a chronic infection caused by Mycobacterium leprae. Leprosy reactions, including erythema nodosum leprosum (ENL), are induced by immune responses. ENL can cause neurological damage and deformities that result in disabilities. This study aimed to identify factors associated with the severity of ENL to help control the leprosy reactions.
Methods: This was an analytical study on 148 patients with ENL reactions, who were divided into two groups based on the severity of their reactions. A retrospective cross–sectional study was conducted in the medical record unit of Sitanala Hospital, Tangerang, Banten, Indonesia, from May 2022 to …
Dietary Organic Selenium Supplementation Improved Some Gross Morphological Parameters And Biochemical Characteristics Of Testes In Young Male Kids, Nadia Rahim, Moolchand Malhi, Asma Babar, Muhammad Awais Soomro, Shazia Rahim
Dietary Organic Selenium Supplementation Improved Some Gross Morphological Parameters And Biochemical Characteristics Of Testes In Young Male Kids, Nadia Rahim, Moolchand Malhi, Asma Babar, Muhammad Awais Soomro, Shazia Rahim
Journal of Bioresource Management
Selenium (Se) plays a vital role in improving reproductive health in ruminants. This study evaluated the impact of Se supplementation on testicular health in young male goats. Twenty goats (2–3 months old, 8.5–10 kg) were randomly assigned to two groups: Control (C, n=10) receiving a basal diet (0.037 mg Se/kg) and Se-Yeast (SY, n=10) supplemented with 0.3 mg Se/kg diet. The trial lasted eight weeks. Results showed that testis weight was significantly higher in the SY group (26.8 ± 2.5 g) compared to C (22.4 ± 2.1 g, p < 0.05). Testis length, width, and circumference also increased significantly in SY goats (4.5 ± 0.3 cm, 2.9 ± 0.2 cm, and 7.4 ± 0.4 cm, respectively) compared to control (3.9 ± 0.4 cm, 2.5 ± 0.3 cm, and 6.7 ± 0.5 cm; p < 0.05). Serum cholesterol was higher in SY (135.27 ± 2.34 mg/dl) than in C (121.15 ± 8.74 mg/dl, p = 0.02), while triglycerides were lower (95.99 ± 1.37 vs. 114.38 ± 1.84 mg/dl, p = 0.0003). HDL increased (51.97 ± 2.10 vs. 45.02 ± 1.32 mg/dl, p = 0.03), and LDL decreased (54.23 ± 1.81 vs. 61.27 ± 1.56 mg/dl, p = 0.02) in SY group. Total serum protein rose significantly (8.14 ± 0.79 vs. 5.25 ± 0.06 mg/dl, p = 0.03), as did testosterone levels (1.95 ± 0.08 vs. 1.43 ± 0.06 ng/ml, p = 0.002). In conclusion, selenium supplementation significantly improved testicular morphology, lipid profile, protein levels, and testosterone, indicating enhanced reproductive health in goats.
Management Of Leiomyoma And Ovarian Cyst With Homoeopathic Medicine Thuja Occidentalis: An Evidence-Based Case Report, Bharti Wadhwa, Sujata Madhukar, Shweta Singh Kureel
Management Of Leiomyoma And Ovarian Cyst With Homoeopathic Medicine Thuja Occidentalis: An Evidence-Based Case Report, Bharti Wadhwa, Sujata Madhukar, Shweta Singh Kureel
Indian Journal of Research in Homoeopathy
Introduction: Leiomyoma (Uterine Fibroid [UF]) is the most prevalent benign solid tumour arising from the neoplastic transformation of smooth muscle cells of myometrium in the reproductive age of females. Fibroids are rare before puberty, increase in prevalence during the reproductive years, and usually reduce in size after menopause.
Case Summary: A 34-year-old woman presented with a complaint of hypogastric pain, and heavy bleeding during her menstrual periods since 3–4 months. Her menstrual cycle was irregular. She was diagnosed with an intramural UF and a right ovarian cyst on ultrasonography. Thuja occidentalis (in different potencies) was prescribed based on …
Role Of Individualised Homoeopathic Treatment In A Case Of Secondary Infertility With Uterine Fibroid Treated Through Psychosomatic Approach: A Case Report, Neha Swarup, Mahesh Gupta, Maneesh Mishra, Sanjay Gupta
Role Of Individualised Homoeopathic Treatment In A Case Of Secondary Infertility With Uterine Fibroid Treated Through Psychosomatic Approach: A Case Report, Neha Swarup, Mahesh Gupta, Maneesh Mishra, Sanjay Gupta
Indian Journal of Research in Homoeopathy
Introduction: Infertility is the inability of a couple to conceive even after being sexually active for a period of one year. It is a fact that the inability to have one’s own child is a grave concern worldwide. Infertility is a globally prevalent condition, with 8–12% of the world population suffering from it. Infertility in females can be due to several causes, one of them is a uterine anomaly like uterine fibroid. Uterine fibroids are generally considered a structural pathology and mostly managed as a surgical condition. A vast literature review emphasises the importance of psychological factors which can lead …
Evaluating The Utilization Of Icd-10 Z-Codes For Documenting Social Determinants Of Health And The Association With Frequent Emergency Department Visits Among Medicaid Beneficiaries, Sofia L. Gomez
Doctoral Dissertations and Projects
This study assesses the use of ICD-10 Z-codes for documenting social determinants of health (SDoH) and examines their relationship with frequent emergency department (ED) visits among Arizona Medicaid-eligible beneficiaries. This retrospective cohort study utilizes claims data from a major Arizona Medicaid payor to explore the frequency of ICD-10 Z-codes use for documenting SDoH, associations between variables, and factors most strongly linked to higher ED utilization. The study sample (N = 53,368) includes Medicaid beneficiaries with ED visits in 2023, including 47,153 individuals without documented SDoH and 6,215 individuals with documented SDoH. Descriptive and statistical analyses, such as binomial tests, chi-square …
Evaluating Patient Readiness For Spine Surgery: A Cross-Sectional Study, Lindsay D. Orosz
Evaluating Patient Readiness For Spine Surgery: A Cross-Sectional Study, Lindsay D. Orosz
Doctoral Dissertations and Projects
Spinal conditions effect millions of Americans each year and surgery for these conditions continues to be on the rise. Historically, spine surgery was associated with negative outcomes and fear, often considered a last resort by both patients and physicians. In the last 20 years, spine surgery has become one of the most rapidly advancing surgical fields and is at the forefront of technological advances and ongoing innovation. Today, spine patients have minimally invasive options that are performed in under half the time and are associated with less muscle weakening and adjacent level irritation, as well as more reliable spinal alignment …
Pulse: Full Issue Download
Quill & Scope
Dear Readers,
I am the soothing beat you hear when your head hits the pillow at night.
I am louder in the silence when you want to be alone with your thoughts.
I am not just a measurement made up of red pixels on a screen.
I keep you alive.
Steady. Persistent.
Who am I?
Pulse. It is one of the first things we check for life. It’s the subtle thrill beneath the surface that reminds us we are here, and we are moving forward. In medicine, the pulse is not just a vital sign; it’s a symbol of …
Core State Injury Prevention Program Listening Sessions Report June 2025 Report, Camille Velarde, Yvonnie Baik, Elena Martinez, Theresa Cruz
Core State Injury Prevention Program Listening Sessions Report June 2025 Report, Camille Velarde, Yvonnie Baik, Elena Martinez, Theresa Cruz
Reports & Documents
Background: Injury and violence remain pressing public health challenges in New Mexico, particularly in rural and underserved communities. To inform prevention strategies, the University of New Mexico Prevention Research Center partnered with the New Mexico Department of Health and local organizations to conduct community listening sessions focused on upstream approaches addressing shared risk and protective factors.
Methods: Four listening sessions were conducted in 2025 with stakeholders from county health councils and community organizations. Using a rapid qualitative analysis approach, researchers analyzed participant perspectives on local injury and violence concerns, familiarity with upstream frameworks, and communication preferences.
Results: Participants identified overlapping …
Acute Pancreatitis Associated With Scrub Typhus: Report Of Two Cases With A Brief Review Of Literature, Atanu Chandra, Rupak Chatterjee, Nandini Chatterjee, Sugata Dasgupta
Acute Pancreatitis Associated With Scrub Typhus: Report Of Two Cases With A Brief Review Of Literature, Atanu Chandra, Rupak Chatterjee, Nandini Chatterjee, Sugata Dasgupta
Sultan Qaboos University Medical Journal
Acute pancreatitis is an exceptionally rare complication of scrub typhus. We report 2 cases of scrub typhus-associated acute pancreatitis from a tertiary care centre in Kolkata, India. The first case was a 27-year-old male patient, who presented in 2023, with severe epigastric pain a few days after the onset of fever. Laboratory investigations confirmed acute pancreatitis associated with scrub typhus. He had no additional organ involvement and recovered fully with intravenous doxycycline. The second case, reported in 2024, was a 42-year-old female patient who presented with fever, abdominal pain, vomiting and systemic complications, including acute kidney injury, hepatic dysfunction and …
Determination Of The Anti-Inflammatory Activity Of The Methanolic Leaf Extract Of Strelitzia Reginae (Strelitziaceae), Lyannah Deign Hearty Delantar Hinol, Miflor De La Cerna, Decethree Gocela, Aymah Macalonto, Junnin Gay Garay
Determination Of The Anti-Inflammatory Activity Of The Methanolic Leaf Extract Of Strelitzia Reginae (Strelitziaceae), Lyannah Deign Hearty Delantar Hinol, Miflor De La Cerna, Decethree Gocela, Aymah Macalonto, Junnin Gay Garay
Pacific Journal of Health
Inflammation is a biological response that, if unregulated, can contribute to various health disorders. The search for new anti-inflammatory agents has led researchers to explore the medicinal potential of Strelitzia reginae, commonly known as the Bird of Paradise. This study aimed to determine the phytochemical composition and anti-inflammatory activity of the methanolic leaf extract of S. reginae. Phytochemical screening confirmed the presence of alkaloids, flavonoids, terpenoids, phenols, saponins, and steroids, while tannins were absent. The Croton Oil-Induced Ear Edema Assay in Swiss albino mice was used to assess anti-inflammatory activity, with Indomethacin as a positive control. Acute oral …
Impact Of Military-Related Moves On Spousal Perinatal Depression Screening And Mental Health Services, Chambraia Jones
Impact Of Military-Related Moves On Spousal Perinatal Depression Screening And Mental Health Services, Chambraia Jones
Walden Dissertations and Doctoral Studies
Maternal depression, including perinatal depression (PND), poses significant public health risks to women, infants, and families. Although routine PND screening is recommended, limited research has examined screening and referrals among military spouses, an underserved population affected by frequent relocations and deployments. This study examined how permanent change of station (PCS) frequency affects PND screening and referrals to mental health services. Grounded in Bronfenbrenner’s socioecological model and the CDC’s social ecological model of health, eight research questions explored associations between PCS frequency, PND screening, referrals, and the moderating roles of military branch and deployment status. A quantitative cross-sectional design was used …
Association Of Anthropometric Indices With Rs9939609 Fto Gene Polymorphism Among Overweight/Obese Women With Breast Cancer: A Case-Control Study, Huma Naqeeb, Bismillah Sehar, Sami Siraj, Ali Madi Almajwal, Bibi Hajira, Moez Al Islam Faris, Sharifa Alblooshi, Ali Saad R. Alsubaie, Mahpara Safdar, Iftikhar Alam, Falak Zeb
Association Of Anthropometric Indices With Rs9939609 Fto Gene Polymorphism Among Overweight/Obese Women With Breast Cancer: A Case-Control Study, Huma Naqeeb, Bismillah Sehar, Sami Siraj, Ali Madi Almajwal, Bibi Hajira, Moez Al Islam Faris, Sharifa Alblooshi, Ali Saad R. Alsubaie, Mahpara Safdar, Iftikhar Alam, Falak Zeb
All Works
Background/objectives: Fat mass and obesity associated (FTO) gene and anthropometric measurements might be associated with breast cancer (BC) risk. This study aimed to assess the interactions between single nucleotide polymorphism (SNP) rs9939609 of the FTO gene, anthropometric indices, and BC risk among pre- and post-menopause women with overweight/obesity in Pakistan. Methods: This retrospective case–control study conducted on a convenience sample of 200 women divided into two groups: a case group comprised of 100 women diagnosed with BC, and control group comprised of 100 (age and menopausal status matched healthy women). Physical activity was assessed using validated questionnaire. Data on body …
Molecular Landscape Of Sex- And Modality-Specific Exercise Adaptation In Human Skeletal Muscle Through Large-Scale Multi-Omics Integration, Macsue Jacques, Shanie Landen, Adam P. Sharples, Andrew Garnham, Ralf Schittenhelm, Joel Steele, Aino Heikkinen, Elina Sillanpää, Miina Ollikainen, James Broatch, Navabeh Zarekookandeh, Ola Hanson, Ola Ekström, Olof Asplund, Séverine Lamon, Sarah E. Alexander, Cassandra Smith, Carlie Bauer, Mary N. Woessner, Itamar Levinger, Andrew E. Teschendorff, Linn Gillberg, Ida Blom, Jørn Wulff Helge, Nicholas Harvey, Larisa M. Haupt
Molecular Landscape Of Sex- And Modality-Specific Exercise Adaptation In Human Skeletal Muscle Through Large-Scale Multi-Omics Integration, Macsue Jacques, Shanie Landen, Adam P. Sharples, Andrew Garnham, Ralf Schittenhelm, Joel Steele, Aino Heikkinen, Elina Sillanpää, Miina Ollikainen, James Broatch, Navabeh Zarekookandeh, Ola Hanson, Ola Ekström, Olof Asplund, Séverine Lamon, Sarah E. Alexander, Cassandra Smith, Carlie Bauer, Mary N. Woessner, Itamar Levinger, Andrew E. Teschendorff, Linn Gillberg, Ida Blom, Jørn Wulff Helge, Nicholas Harvey, Larisa M. Haupt
Research outputs 2022 to 2026
We investigated the molecular mechanisms of exercise adaptations in human muscle by integrating genome, methylome, transcriptome, and proteome data from over 1,000 participants (2,340 muscle samples). We identified distinctive signatures associated with maximal oxygen consumption (VO2max), and multi-omics integration uncovered five key genes as robust exercise markers across layers, with transcription factors functioning as activators, synergizing with DNA methylation to regulate gene expression. Minimal sex differences were observed, while modality-specific analysis highlighted distinct pathways for aerobic and resistance exercise, contrasting with muscle disuse patterns. Finally, we created a webtool, OMAx, featuring our individual omics and integration analysis. These findings provide …
The Relationship Between Prenatal Stressful Life Events And Breastfeeding Initiation Among Mississippi Mothers, Candon Garbo, Katie C. Hall, Disha Jhaveri, Jung Hye S. Lee, Deanna Howington, Mina Qobadi, Mary Wesley
The Relationship Between Prenatal Stressful Life Events And Breastfeeding Initiation Among Mississippi Mothers, Candon Garbo, Katie C. Hall, Disha Jhaveri, Jung Hye S. Lee, Deanna Howington, Mina Qobadi, Mary Wesley
Journal of Public Health in the Deep South
Background: Early initiation of breastfeeding increases the likelihood of exclusive breastfeeding, which can be linked to improving both the mother’s and infant’s health. However, breastfeeding rates in Mississippi continue to be one of the lowest in the United States, with infant mortality and morbidity rates at the highest. Purpose: This study aims to explore the impact SLEs may have on initiating breastfeeding, as research is limited. Methods: Analyzed data from 2016 to 2021 Pregnancy Risk Assessment and Monitoring System (PRAMS) was used to determine a correlation between life stressor experiences during pregnancy and initiation of exclusive breastfeeding with a sample …
Healthy Moms/Healthy Babies Of Mississippi Initial Provider Engagement And Student Feedback Loop Project, Corban Jackson Mph, Jillian Harper-Peavy Lmsw, Imh-E, Starica Harper, Vernesia Wilson Phd, Mph
Healthy Moms/Healthy Babies Of Mississippi Initial Provider Engagement And Student Feedback Loop Project, Corban Jackson Mph, Jillian Harper-Peavy Lmsw, Imh-E, Starica Harper, Vernesia Wilson Phd, Mph
Journal of Public Health in the Deep South
Background Between 2017 and 2022, 83% of maternal deaths in Mississippi were preventable. Unfortunately, there is a persistent shortage of OB-GYNs in Mississippi, feeding the rise of maternal care deserts and the lapse in collaboration between providers and state maternal health organizations. Purpose Healthy Moms/Healthy Babies of Mississippi, a care management program for high-risk mothers and infants, has partnered with the Mississippi Alliance for Innovation on Maternal Health initiative (AIM) to improve maternal health outcomes through building healthcare networks with existing providers. Methods 33 medical students from the University of Mississippi Medical Center School of Medicine and William Carey University …
Hypertensive Disorders Of Pregnancy And Perinatal Outcomes: Two Prospective Cohort Studies Of Nulliparous Women In India And Tanzania, Andrea B. Pembe, Pratibha Dwarkanath, Amani Kikula, John Michael Raj, Nandita Perumal Phd, Heavenlight A. Paulo, Rajalakshmi M, Christopher P. Duggan, Honorati M. Masanja, Nandini Chopra, Mary M. Sando, Tinku Thomas, Cara A. Yelverton, Alfa Muhihi, Anura V. Kurpad, Wafaie E. Fawzi, Blair J. Wylie, Christopher R. Sudfeld
Hypertensive Disorders Of Pregnancy And Perinatal Outcomes: Two Prospective Cohort Studies Of Nulliparous Women In India And Tanzania, Andrea B. Pembe, Pratibha Dwarkanath, Amani Kikula, John Michael Raj, Nandita Perumal Phd, Heavenlight A. Paulo, Rajalakshmi M, Christopher P. Duggan, Honorati M. Masanja, Nandini Chopra, Mary M. Sando, Tinku Thomas, Cara A. Yelverton, Alfa Muhihi, Anura V. Kurpad, Wafaie E. Fawzi, Blair J. Wylie, Christopher R. Sudfeld
Faculty Publications
Introduction Hypertensive disorders of pregnancy (HDP) have been linked with increased risk for maternal and offspring complications in high-income settings. However, in resource-limited settings, studies with robust measurement of HDP, including severity and timing, and perinatal outcomes are limited.
Methods We analysed data from two prospective cohorts of nulliparous women in India (n=10 570 pregnancies) and Tanzania (n=10 299 pregnancies) who were enrolled in calcium supplementation trials and had blood pressure and proteinuria assessments throughout pregnancy and at the time of labour and delivery. Generalised estimating equations were used to assess the relationship between HDP severity categories (gestational hypertension, preeclampsia …
Resveratrol And Il-6 Modulation Of Cxcl1 Expression And Viability In Human Breast Cancer Cell Lines, Entkhab M. A. Alanisi, Aida H. Alobaidi, Khalid Alyodawi
Resveratrol And Il-6 Modulation Of Cxcl1 Expression And Viability In Human Breast Cancer Cell Lines, Entkhab M. A. Alanisi, Aida H. Alobaidi, Khalid Alyodawi
AUIQ Complementary Biological System
This study aims to investigate, through in vitro methods, the molecular, immunofluorescent, and immunohistochemical effects of resveratrol and IL-6 on CXCL1 gene/protein expression in human breast cancer cells (MCF-7). MCF-7 and MCF-10A cell lines were cultured and divided into four groups: control, IL-6-treated, resveratrol-treated, and a combination-treated group. CXCL1 gene expression was assessed by real-time PCR (RT-PCR), while CXCL1 protein levels were analyzed using immunofluorescence and immunohistochemistry. Cell viability was quantified by MTS assay using ELISA. CXCL1 gene/protein was overexpressed in MCF-7 cells, especially in the IL-6-treated group, but reduced in both resveratrol and combination-treated groups. MTS assay showed increased …
Expert Opinion On Clinical Presentation, Diagnosis And Treatment Of Infantile Onset Pompe Disease: A Delphi Study In Türkiye, Eki̇n Özsaydi Aktaşoğlu, Asli İnci̇, Ridvan Murat Öktem, Gürsel Bi̇beroğlu, İlyas Okur, Fati̇h Süheyl Ezgü, Fi̇li̇z Başak Cengi̇z Ergi̇n, Abdurrahman Akgün, Nur Arslan, Hali̇l İbrahi̇m Aydin, Ayşe Ergül Bozaci, Mahmut Çoker, Fatma Tuba Emi̇noğlu, Meli̇ke Ersoy, Emi̇ne Göksoy, Banu Kadioğlu Yilmaz, Mehtap Kağnici, Mustafa Kiliç, Nesli̇han Önenli̇ Mungan, Burcu Öztürk Hişmi̇, Pembe Soylu Üstkoyuncu, Ayşegül Tokatli, Ayşe Çi̇ğdem Aktuğlu Zeybek, Berrak Bi̇lgi̇ner Gürbüz, Sevi̇l Dorum, Di̇lek Güneş, Çi̇ğdem Seher Kasapkara, Sebi̇le Kilavuz, Erdoğan Soyuçen, Peli̇n Teke Kisa, Özlem Ünal Uzun, Fatma Derya Bulut, Songül Gökay, Selen Has Özhan, Deni̇z Kor, Aynur Küçükcongar Yavaş, Fi̇gen Özçay, Yilmaz Yildiz, Harun Yildiz, Leyla Tümer
Expert Opinion On Clinical Presentation, Diagnosis And Treatment Of Infantile Onset Pompe Disease: A Delphi Study In Türkiye, Eki̇n Özsaydi Aktaşoğlu, Asli İnci̇, Ridvan Murat Öktem, Gürsel Bi̇beroğlu, İlyas Okur, Fati̇h Süheyl Ezgü, Fi̇li̇z Başak Cengi̇z Ergi̇n, Abdurrahman Akgün, Nur Arslan, Hali̇l İbrahi̇m Aydin, Ayşe Ergül Bozaci, Mahmut Çoker, Fatma Tuba Emi̇noğlu, Meli̇ke Ersoy, Emi̇ne Göksoy, Banu Kadioğlu Yilmaz, Mehtap Kağnici, Mustafa Kiliç, Nesli̇han Önenli̇ Mungan, Burcu Öztürk Hişmi̇, Pembe Soylu Üstkoyuncu, Ayşegül Tokatli, Ayşe Çi̇ğdem Aktuğlu Zeybek, Berrak Bi̇lgi̇ner Gürbüz, Sevi̇l Dorum, Di̇lek Güneş, Çi̇ğdem Seher Kasapkara, Sebi̇le Kilavuz, Erdoğan Soyuçen, Peli̇n Teke Kisa, Özlem Ünal Uzun, Fatma Derya Bulut, Songül Gökay, Selen Has Özhan, Deni̇z Kor, Aynur Küçükcongar Yavaş, Fi̇gen Özçay, Yilmaz Yildiz, Harun Yildiz, Leyla Tümer
Turkish Journal of Medical Sciences
Background/aim: Pompe disease (acid maltase deficiency, glycogen storage disease type II, OMIM #606800) is an autosomal recessive disorder characterized by lysosomal acid-α-glucosidase deficiency. The infantile-onset type of the disease is mainly characterized by cardiomegaly, hypotonia, and a high mortality rate. This study aimed to create a national consensus about infantile-onset Pompe disease (IOPD) to raise awareness among clinicians and standardize diagnosis and treatment approaches in Türkiye.
Materials and methods: The Gazi University Division of Metabolic Diseases and Nutrition developed this expert opinion consensus and expanded it to include metabolism specialists across Türkiye. A systematic literature review was performed, and the …
The Role Of The Hemoglobin-Albumin-Lymphocyte-Platelet (Halp) Score In Deep Neck Infections And Its Relationship With Clinical Parameters, Ayşe Seçi̇l Kayali Di̇nç, Nagi̇han Gülhan Yaşar, Agah Yeni̇çeri̇, Çeti̇n Şahutoğlu, İbrahi̇m Sevi̇m, Meli̇h Çayönü
The Role Of The Hemoglobin-Albumin-Lymphocyte-Platelet (Halp) Score In Deep Neck Infections And Its Relationship With Clinical Parameters, Ayşe Seçi̇l Kayali Di̇nç, Nagi̇han Gülhan Yaşar, Agah Yeni̇çeri̇, Çeti̇n Şahutoğlu, İbrahi̇m Sevi̇m, Meli̇h Çayönü
Turkish Journal of Medical Sciences
Background/aim: Deep neck infections (DNI) are suppurative infections of the cervical spaces, which may lead to life-threatening complications. The HALP score is a laboratory parameter reflecting a patient’s nutritional and inflammatory status. The aim of this study was to compare the HALP scores of patients with DNI with those of a control group. A secondary objective was to investigate the potential relationship between the HALP score and clinical parameters, and to assess its role in determining disease severity.
Materials and methods: The study retrospectively included patients who were hospitalized and treated for DNI. Data were extracted from the hospital’s electronic …
Investigation Of The Relationship Between Triglyceride Glucose Index And Metabolic And Hematological Parameters In Obese Individuals, Özge Baş Aksu, Feri̇de Özkara, Rifat Emral, Volkan Genç, Demet Çorapçioğlu, Mustafa Şahi̇n
Investigation Of The Relationship Between Triglyceride Glucose Index And Metabolic And Hematological Parameters In Obese Individuals, Özge Baş Aksu, Feri̇de Özkara, Rifat Emral, Volkan Genç, Demet Çorapçioğlu, Mustafa Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: This research examined the association between the triglyceride-glucose (TyG) index and metabolic, hepatic, and hematologic variables in a population of severely obese subjects, with a focus on the assessment of glycemic control.
Materials and methods: This retrospective study included 315 adult patients with a body mass index (BMI) ≥ 35 kg/m² who were evaluated for bariatric surgery. Participants were grouped according to HbA1c levels: those with HbA1c ≥ 6.5% and those with HbA1c < 6.5%. TyG, atherogenic index of plasma (AIP), fibrosis-4 (FIB-4), aspartate aminotransferase-to-platelet ratio index (APRI), and hematological inflammation markers were assessed and compared between groups. To investigate associations, correlation and regression analyses were conducted.
Results: Individuals with HbA1c ≥ 6.5% had significantly higher TyG, AIP, APRI, and FIB-4 values than those with lower HbA1c. The TyG index showed a strong …
Health Impacts And Medical Assistance After Libyan Flood Disaster: Emergency Medical Teams’ Responses, Hakan Güner, Okan Maden, Muhammed Saltuk Deni̇z, Kerem Dost Bi̇lmez, Şükrü Yorulmaz, Mehmet Enes Gökler
Health Impacts And Medical Assistance After Libyan Flood Disaster: Emergency Medical Teams’ Responses, Hakan Güner, Okan Maden, Muhammed Saltuk Deni̇z, Kerem Dost Bi̇lmez, Şükrü Yorulmaz, Mehmet Enes Gökler
Turkish Journal of Medical Sciences
Background/aim: Floods are the most frequent natural disasters and pose direct and indirect health risks, some well-documented and others poorly understood. Epidemiological studies help bridge these gaps and guide effective public health responses.In September 2023, Storm Daniel caused severe flooding in Libya, damaging infrastructure, including healthcare facilities. The disaster affected 250,000 people, displaced 48,000, and claimed 15,000 lives, making it the second deadliest natural disaster of the year. This study aims to assess the characteristics of flood-affected patients to improve disaster preparedness.
Materials and methods: This descriptive study examined disaster victims who visited three clinics established as part of an …
Nosocomial Sepsis Triggered By Pluralibacter Gergoviae In A Pediatric Intensive Care Unit: A Case Report And Literature Review, Abdulrahman Özel, Nurettin Onur Kutlu, Servet Yüce, Cenk Özdalgiçoğlu, Meltem Erol
Nosocomial Sepsis Triggered By Pluralibacter Gergoviae In A Pediatric Intensive Care Unit: A Case Report And Literature Review, Abdulrahman Özel, Nurettin Onur Kutlu, Servet Yüce, Cenk Özdalgiçoğlu, Meltem Erol
Journal of Pediatric Infectious Diseases
Pluralibacter gergoviae is a rare opportunistic gram-negative bacillus in humans and exhibits resistance to preservatives in cosmetic products. In this case report, we present nosocomial P. gergoviae sepsis that developed through contamination from a cleaning product in a previously healthy child without known chronic diseases, pediatric intensive care unit care. Contamination with the same microorganism was detected even in unused samples of the cleaning product, leading to a recall of these items. This report highlights the case of hospital-acquired P. gergoviae sepsis to emphasize the importance of adherence to antiseptic protocols by health care work as well as the necessity …
Comparison Of Delta Neutrophil Index And Inflammatory Markers In The Diagnosis Of Late-Onset Neonatal Sepsis In Preterm Infants, Aybuke Yazici, Hayriye Gozde Kanmaz Kutman, Gulsum Kadioglu Simsek, Betul Siyah Bilgin, Fuat Emre Canpolat, Bedia Dinc, Serife Suna Oguz
Comparison Of Delta Neutrophil Index And Inflammatory Markers In The Diagnosis Of Late-Onset Neonatal Sepsis In Preterm Infants, Aybuke Yazici, Hayriye Gozde Kanmaz Kutman, Gulsum Kadioglu Simsek, Betul Siyah Bilgin, Fuat Emre Canpolat, Bedia Dinc, Serife Suna Oguz
Journal of Pediatric Infectious Diseases
Objective: To assess the performance of the relatively new hematological marker delta neutrophil index (DNI) and other inflammatory markers in proven sepsis of the very preterm infant.
Methods: Infants with a gestational age of <32 weeks and examined for suspected late-onset sepsis (LOS) were evaluated retrospectively. Demographic characteristics, laboratory findings, and neonatal morbidity and mortality were compared between infants with blood culture-confirmed sepsis and clinical sepsis.
Results: The study included 358 infants, 90 with proven sepsis and 268 with clinical sepsis. The mean gestational ages in these groups were 28.2±2 and 28.2±2.1 weeks, and the mean birth weight was 1139±372 and 1148±370 g, respectively (p>0.05). The proven sepsis group had higher DNI (median 7.1% [range, 0.1-74] vs. 0.6% [range, 0.1-24.7%], p<0.01], CRP (median 5 [range, 1-38] mg/L vs. 1 [range, 1-15] mg/L, p<0.001), interleukin 6 (median 620 [range, 6.9-5500] pg/mL vs. 42.2 [range, 2.2-5500] pg/mL, p<0.01), and procalcitonin (median 6.2 [range, 0.26-86] μg/L vs. 0.6 [range, 0.06-25.7] μg/L, p=0.002). According to ROC analysis, interleukin 6 had the highest area under the curve (AUC) at 0.74 (95% CI 0.60-0.88, p<0.01). The AUC values were 0.73 (95% CI 0.59-0.88, p=0.01) for procalcitonin, 0.62 (95% CI 0.44-0.80, p=0.18) for DNI, and 0.66 (95% CI 0.50-0.82, p=0.05) for CRP.
Conclusion: The delta neutrophil index showed a statistically significant elevation …
0.01],>32>Evaluation Of Gastrointestinal Pathogens In Children With Inflammatory Bowel Disease Using Multiplex Polymerase Chain Reaction, Yeliz Çağan Appak, Özgür Appak, Betül Aksoy, Büşra Emi̇r, Ayça Arzu Sayiner, Maşallah Baran
Evaluation Of Gastrointestinal Pathogens In Children With Inflammatory Bowel Disease Using Multiplex Polymerase Chain Reaction, Yeliz Çağan Appak, Özgür Appak, Betül Aksoy, Büşra Emi̇r, Ayça Arzu Sayiner, Maşallah Baran
Journal of Pediatric Infectious Diseases
Objective: Impaired gastrointestinal mucosa and immunosuppressant therapies increase the risk of secondary infection in patients with inflammatory bowel disease (IBD). This study evaluated the detection of pathogens in children with IBD using a gastrointestinal panel (GP). This is the first study to compare this method with clinical data from pediatric IBD patients.
Methods: Children with newly diagnosed IBD or experiencing disease flares were included. Demographic data, clinical and laboratory findings, treatments, treatment durations, and disease activity were analyzed. Stool samples were assessed using multiplex real-time polymerase chain reaction with QIAstat-Dx GP®. Results were compared between groups.
Results: Thirty-five patients with …
Holistic Care For Breastfeeding Patients: Supporting Lactation In Critical Care, Marisa Francis Dnp, Rn, Cne, Clc, Adreanne Cordova Msn, Rn, Cne, Chse, Clc
Holistic Care For Breastfeeding Patients: Supporting Lactation In Critical Care, Marisa Francis Dnp, Rn, Cne, Clc, Adreanne Cordova Msn, Rn, Cne, Chse, Clc
Nursing Research and Scholarship
This poster emphasizes the critical need for support for breastfeeding patients in critical care units, such as Adult ICUs and Emergency Departments. Many breastfeeding patients experience disrupted breastfeeding during hospitalization, leading to issues like engorgement, mastitis, decrease in milk supply, and loss of the breastfeeding bond. Despite this, the importance of maintaining breastfeeding during hospitalization is often overlooked, and patients are often told to "pump and dump" (discard expressed milk), a practice that can harm both the infant's nutrition and the breastfeeding relationship.
Research indicates that continued breastfeeding for patients in critical care areas is safe and beneficial for both …
Implementation And Effectiveness Of A Nurse-Enabled, Shared-Care Follow-Up Model For Early Breast Cancer Survivors (The Ibis-Survivorship Study): Protocol For A Stepped-Wedge Cluster Randomised Trial, Raymond J. Chan, Fiona Crawford-Williams, Bogda Koczwara, G. Bruce Mann, Elizabeth Eakin, Jane Turner, Meinir Krishnasamy, Louisa G. Collins, Helen Skerman, Karla Hemming, Nicolas H. Hart, Jon Emery, Bethany Crowe, Kerry Patford, Jane Mahony, Caroline Kristunas, Gillian Blanchard, Laura Healey, Jasotha Sanmugarajah, Rhea Liang, Paul Craft, Amy Shorthouse, Ruth Mccaffery, Mary Azer, Patsy Yates
Implementation And Effectiveness Of A Nurse-Enabled, Shared-Care Follow-Up Model For Early Breast Cancer Survivors (The Ibis-Survivorship Study): Protocol For A Stepped-Wedge Cluster Randomised Trial, Raymond J. Chan, Fiona Crawford-Williams, Bogda Koczwara, G. Bruce Mann, Elizabeth Eakin, Jane Turner, Meinir Krishnasamy, Louisa G. Collins, Helen Skerman, Karla Hemming, Nicolas H. Hart, Jon Emery, Bethany Crowe, Kerry Patford, Jane Mahony, Caroline Kristunas, Gillian Blanchard, Laura Healey, Jasotha Sanmugarajah, Rhea Liang, Paul Craft, Amy Shorthouse, Ruth Mccaffery, Mary Azer, Patsy Yates
Research outputs 2022 to 2026
Introduction Breast cancer is the most commonly diagnosed cancer among women worldwide. Survivors often experience physical and psychological effects arising from breast cancer and its treatment, which can last months and years, adversely impacting quality of life. As the number of early breast cancer survivors increases, models of specialist-led follow-up care in hospital settings are not sustainable and evidence suggests that they may not meet survivors’ needs. Nurse-enabled, shared-care, follow-up models between cancer specialist and primary care teams have potential to address this need. Methods and analysis The proposed research is a multicentre, prospective, pragmatic, stepped-wedge cluster-randomised trial designed to …
Navigating Care And Loss Through Aging, Disease, And Decision-Making In The Covid Era, Michael Predi, Do
Navigating Care And Loss Through Aging, Disease, And Decision-Making In The Covid Era, Michael Predi, Do
The Medicine Forum
There is only one of the loved one you know.
Often it can be hard to let go.
Five years old the world became cold.
Lost my mother to breast cancer.
A cold wound that can’t be answered
Father raised you in a foreign land.
Drove you to school, combed your hair, gave you a life you could have never planned.
Taught me that I would catch a cold from the wind.
No arguing about modern medicine, my dad was thick skinned,
Here comes college, first generation, what an exciting time.
Get to medical school so exciting; here comes the …
Investigating The Link Between Ulcerative Colitis And Papillary Thyroid Carcinoma: A Case Report, Sonali Shah, Md, Emily Chiacchiaro, Md, Priya Sehgal, Md
Investigating The Link Between Ulcerative Colitis And Papillary Thyroid Carcinoma: A Case Report, Sonali Shah, Md, Emily Chiacchiaro, Md, Priya Sehgal, Md
The Medicine Forum
Inflammatory bowel diseases (IBD) are chronic inflammatory conditions that primarily involve the gastrointestinal tract, but also cause widespread systemic inflammation. There have been multiple studies investigating the link between ulcerative colitis (UC) and crohn’s disease (CD) and thyroid diseases, as the incidence is greater than the general population.1 In addition, patients with IBD have been found to be at increased risk of developing both intestinal malignancies and extra-intestinal malignancies.2 Literature review suggests a possible connection between ulcerative colitis and papillary thyroid cancer, with most studies concluding there is a higher risk of PTC in patients with UC, but …
When Access Is Not Enough: The Role Of Utilization Barriers In Nutrition Security And Cardiometabolic Risk, Maha Almohamad, Ruosha Li, Natalia I Heredia, Jayna M Dave, Eric E Calloway, Anjail Z Sharrief, Shreela V Sharma
When Access Is Not Enough: The Role Of Utilization Barriers In Nutrition Security And Cardiometabolic Risk, Maha Almohamad, Ruosha Li, Natalia I Heredia, Jayna M Dave, Eric E Calloway, Anjail Z Sharrief, Shreela V Sharma
Faculty, Staff and Student Publications
Background: Food and nutrition security are key social determinants of cardiometabolic health. While food security reflects access to sufficient food, nutrition security incorporates the quality, consistency, and usability of food that supports long-term health. However, few studies have examined how household-level barriers to food utilization shape these relationships. Objective: This study assessed whether tangible (e.g., equipment, storage) and intangible (e.g., time, knowledge) food utilization barriers modify the associations between food and nutrition security and cardiometabolic outcomes in low-income adults.
Methods: A cross-sectional survey was conducted among 486 low-income adults across five U.S. states. Participants reported household food security (USDA …
Exploring The Interplay Between Kidney Dysfunction And Cardiovascular Disease, Rajesh Yadav, Aqsa Kaim Abubakar, Richa Mishra, Saurabh Gupta, Neelesh Kumar Maurya, Vivek Kashyap, Sarvesh Rustagi, Deependra Pratap Singh, Sanjay Kumar
Exploring The Interplay Between Kidney Dysfunction And Cardiovascular Disease, Rajesh Yadav, Aqsa Kaim Abubakar, Richa Mishra, Saurabh Gupta, Neelesh Kumar Maurya, Vivek Kashyap, Sarvesh Rustagi, Deependra Pratap Singh, Sanjay Kumar
School of Medicine Publications
This article reveals the various types of complications that are associated with dialysis and kidney-associated disease, including left ventricular hypertrophy, heart failure, vascular heart disease, arrhythmias, diabetes mellitus, intradialytic hypertension, and coronary heart disease. The molecular mechanisms underlying the development of cardiovascular disease in patients with chronic kidney disease (CKD), including the role of nitric oxide (NO) signaling, have been extensively studied. Patients suffering from CKD need treatment with hemodialysis at the end stages. The kidney is considered the chief excretory organ in humans, which excretes various types of waste materials from the body and balances the acid–base ratio, due …