Digital Commons Network^™

Exploring Stunting In South Kalimantan Province Using R Programming-Based Data Visualization, Muhammad Hudaya, Wahyudin Nor, Mellani Yuliastina, Muhammad Nordiansyah

Kesmas

South Kalimantan Province continues to face the challenge of relatively high stunting prevalence despite being endowed with abundant coal resources that could serve as a source of funding for public health. Therefore, this study aimed to examine differences in stunting prevalence among cities, mining districts, and non-mining districts in South Kalimantan to raise stakeholder awareness of disparities across these regional types. This study was conducted between April and December 2024, using secondary data obtained from the Indonesian Ministry of Health and the South Kalimantan Provincial Government. R programming was used to process the data, generate visualizations, and perform analysis of …

Assessment Of The Dietary Supplements Effects On Maternal Underweight In Nigeria, Chukwuebuka Jude Chiobi, Uzoamaka Angela Chiobi, Ambrose Nnaemeka Omeje, Ikechukwu Andrew Mobosi, Michael Okike Ugwu, Nnamdi Simeon Ugwu

Kesmas

Maternal underweight continues to rise and, if not properly managed, will lead to increased mortality. This contradicts the United Nations Sustainable Development Goal of reducing maternal mortality by 2050. Therefore, this study aimed to determine the probable effect of dietary supplements on maternal underweight in Nigeria. This study employed probit estimation using the maximum likelihood technique in 2022, with the 2018 Nigeria Demographic Health Survey data as the basis for analysis. The results showed a statistically significant effect of dietary supplements on maternal underweight in Nigeria. The likelihood of dietary supplements impacting maternal underweight was approximately 0.4% lower, on average, …

An Investigation Into The Potent Anticancer, Antimicrobial, And Anti-Inflammatory Activities Of A Punica Granatum Nanoemulgel, Ahmad M Eid, Murad Abualhasan, Yara Khaliliya, Zeina Sinan, Aya Khaliliya

BioMedicine

Purpose: The objective of this study is to formulate a nanoemulgel using Punica granatum (P. granatum) seed oil and study the antibacterial, anticancer, and anti-inflammatory properties. Methods: The process to formulate a nanoemulsion from P. granatum seed oil involved using the self-nanoemulsifying technique, with Span 80 and Tween 80 serving as the emulsifying agents. Carbopol hydrogel was combined with the nanoemulsion to produce the nanoemulgel. The particle size, polydispersity index (PDI), rheological behavior, antibacterial, cytotoxic, and anti-inflammatory properties were subsequently examined.

Results: The nanoemulsion formulation with a PDI of 0.229 and a particle size of 189.44 nm was …

Quality Of Life Among Type Ii Diabetes Mellitus Patients, Duaa Dhia Hameed Al-Baghdadi, Rajha Abdul Hassan Hamza

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

Background: Type 2 diabetes mellitus (T2DM) is a significant public health concern Approximately 90% of people with diabetes worldwide have diabetes mellitus type 2. Methods: A cross-sectional study was conducted from October 23, 2023, to March 2, 2025, in Al-Najaf Al-Ashraf City to assess the quality of life among individuals with T2DM. A non-probability sampling technique (purposive sampling) was used to select 167 T2DM patients. Data were collected through a questionnaire, which consisted of three parts: Part I covered sociodemographic information, Part II focused on clinical data, and Part III addressed the quality of life among T2DM patients by using …

Using Dexcom G7 In Critically Ill Infant With Hyperinsulinemia On High Frequency Oscillatory Ventilation Support, Chad E. Ward, Timothy Clark, Eric Velezquez

HCA Healthcare Journal of Medicine

Introduction

Life threatening hypoglycemia can occur during critical illness in infants with underlying hyperinsulinemia or metabolic conditions, such as glycogen storage diseases. Using a continuous glucose monitor (CGM) can provide insight into glycemic trends with this high-risk patient population in the intensive care setting. Barriers to usage of CGMs in the intensive care unit include familiarity with CGMs devices among staff, safety, and cost.

Case Presentation

We describe the first reported case of safely utilizing the newest Dexcom G7 continuous glucose monitor in an infant with hyperinsulinemia undergoing high frequency oscillatory ventilator (HFOV) support for acute respiratory distress syndrome (ARDS) …

A Hard Problem: Managing Constipation In The Geriatric Population, William G. Jones, Veeraen Jonnalagadda, Alexandra E. Thomson, Victoria Grumbles, Chase Cottle, Christian Robertson, Maulikkumar Patel

HCA Healthcare Journal of Medicine

Constipation is a common condition among geriatric patients with different presenting symptoms and potential serious complications. Additionally, the condition causes a significant burden on our healthcare system. Here, we summarized recommendations from several societies, including the American College of Gastroenterology, American Geriatrics Society, and American Academy of Family Physicians to provide guidance on managing constipation with geriatric patients. Our aim was to emphasize the importance of prevention of constipation in this population and methods to do so. We also give recommendations on how to manage constipation when it does develop and how to manage it across different healthcare settings. These …

Low Economic Level And The Risk Of Overweight Among Indonesian Junior And Senior High School Students, Ariyanto Nugroho, Purwo Setiyo Nugroho, Amarin Yudhana, Sri Sunarti

Kesmas

Overweight and obesity among Indonesian adolescents have emerged as a pressing public health issue, reflecting global trends. This study examines the relationship between economic status and overweight prevalence among junior and senior high school students in Indonesia, using secondary data from the Global School-based Health Survey (GSHS). This study analyzed data from 9,977 students aged 11–18 years through a cross-sectional design and binary logistic regression, adjusting for dietary habits, physical activity, and sedentary behavior. Overall, 14.7% of students were overweight; the prevalence was notably higher among low-income students (27.4%) compared to high-income groups (14.2%). Students from lower economic backgrounds were …

Decreasing The Incidence Of Healthcare Associated Presure Injuries In The Acute Care Setting, Amanda R. Nichols

Doctoral Dissertations and Projects

Healthcare-associated pressure injuries (HAPIs) can cause great harm to vulnerable patients. Acquiring a HAPI during hospitalization can result in delayed wound treatment, prolonged hospitalization, risk for infection, reimbursement issues for the facility, and delayed patient discharge. Avoiding these injuries is essential to improve patient outcomes. Research reveals that the implementation of nurse education and two registered nurse skin assessments on admission, instead of one nurse skin assessment, can decrease the incidence of healthcare-associated pressure injuries. Using the Iowa model, the goal of this scholarly project is to implement evidence-based research to change the current process and decrease the incidence of …

Evaluating Inclusion Rates Of Oral-Systemic Health Connection Coursework In Dental And Medical Professional Programs' Admissions Requirements, Wendy Marie Carry

Doctoral Dissertations and Projects

Oral systemic health connections (OSHC) are bidirectional, life-threatening, and a significant public health concern. Studies have identified over 200 OSHCs; however, the prevalence of foundational OSHC education in dental and medical professional programs remains unknown. This quantitative descriptive comparative pilot study aimed to explore the prevalence of predictor variables, dental and medical professional programs in the United States, and the criterion variable, including an OSHC admissions requirement for the 2025 academic year. The point-in-time count methodology served as the theoretical framework guiding this study and the development of the PiT-PARCI instrument. The proposed testing was replaced with alternative testing based …

The Impact Of Resistance Training On Obese Perimenopause African American Women In San Antonio, Letesha Nicole Butler

Doctoral Dissertations and Projects

This quantitative randomized controlled trial investigated the impact of resistance training on body fat in obese African American perimenopausal women in San Antonio, Texas. The study aimed to support the World Health Organization's efforts to combat obesity and address the underrepresentation of African American women in research, a population with over half being overweight or obese. Eleven eligible participants completed an intake survey and had their body fat percentage measured using an InBody 270 before and after the intervention. Participants were divided into two groups: one utilizing weights (e.g., dumbbells, barbells, machines, resistance bands) and the other using body weight …

Associations Between Factors Of Unhealthy Lifestyle, Mental Health Issues, Chronic Illnesses, Environmental Health Risks, And Infertility In Females: A Cross-Sectional Study, Richard L. Huang

Doctoral Dissertations and Projects

Infertility has risen rapidly in recent decades and has become the third-largest public health concern in the world. It has significantly threatened individuals’ psychological, physical, and social well-being, and it could be an early sign of severe health problems in the future. Furthermore, it also threatens the continuation of life and human civilization. The purpose of this study was to examine the relationship between individuals’ daily lifestyle behaviors, mental health status, chronic conditions, environmental health factors, and infertility by using cross-sectional quantitative methods. It benefits the public as the study raised awareness of potential risks and provided guidance to avoid …

The Impact Of Cold-Water Immersion On Mental Health: A Qualitative Study, Marcus Jean-Francois

Doctoral Dissertations and Projects

Historically, Cold Water Immersion (CWI) was used for physical therapy and is now a potential non-pharmacological intervention for mental health illnesses such as depression, stress and anxiety. In this study in Kota Kinabalu, Sabah, Malaysia, we examined the personal experiences on the psychological impact of CWI on mental health. We examined twelve participants between 20-35 years of age that had a self-diagnosed mental illness to participate in six CWI sessions over the span of three weeks. This study predicts that CWI will have a significant reduction in their mental health illness compared to baseline levels. Employing a Hermeneutic Phenomenological approach, …

Enhancing Parental Knowledge Of Functional Medicine Interventions For Adhd: An Educational Initiative To Improve Caregiver Competency, Julie Gammer

Doctoral Dissertations and Projects

Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent pediatric psychiatric condition often managed with stimulant medications that carry potential side effects and may not address underlying causes. Research findings indicate a significant gap in caregiver knowledge and confidence in treating their child's ADHD with functional medicine strategies. This project develops an evidence-based educational initiative designed to enhance caregiver knowledge and confidence in applying functional medicine interventions—such as dietary modifications, targeted supplementation, and gut health restoration—as natural, root-cause approaches to managing ADHD symptoms. The project utilized a 30-minute audiovisual presentation and was evaluated using pre- and post-intervention competency tests, as well as a …

Investigating “Sled Head” Phenomenon And Diurnal Patterns In Team Usa Bobsleigh And Luge Athletes: A Virtual Research Study, Garrett R. Augsburger

Doctoral Dissertations and Projects

This study investigated the relationship between training time, performance, and concussion symptoms among Team USA bobsleigh and luge athletes during a four-week training season. Recognizing the high physical demands and potential risks associated with sledding sports, the study aimed to understand the prevalence of concussion-related experiences and how training schedules might influence athletic performance and symptomology. Repeated measures quantitative design was employed using session-level survey data submitted by athletes following daily training sessions. Data was collected through a structured questionnaire assessing variables such as performance rating, fatigue, alertness, training intensity, sleep quality, and concussion symptoms. A total of 156 sessions …

The Effects Of The Menstrual Cycle On Movement Velocity In Female Athletes, Casey M. Krolikowski

Doctoral Dissertations and Projects

This study examined the psychological and physiological impacts of menstrual cycle phase and hormonal contraceptive (HC) use on barbell back squat and bench press velocity, handgrip strength, and countermovement jump height. The aim was to determine whether HC use and premenstrual syndrome (PMS) symptoms affected performance during menstruation, the late follicular phase (LFP), or the mid-luteal phase (MLP). Fourteen college-aged female athletes (N = 14) were divided into HC users (n = 7), and naturally menstruating, eumenorrheic individuals (n = 7). Movement velocity data was assessed using RepOne linear position transducers, jump height with the Just Jump mat, and grip …

An Analysis Of Sport Science Practices And Standards In Collegiate Football, Corey F. Fitzgerald

Doctoral Dissertations and Projects

This dissertation presents the findings of a survey that identifies the sport science practices and standards utilized in National Collegiate Athletic Association (NCAA) football programs. In total a fifty-two item survey instrument was administered that examines seven sections, including (i) demographics, (ii) current sport science practices, (iii) advanced technology, (iv) decision-making processes, (v) health and wellness, (vi) budget and resources, and (vii) comments. All generated numerical data was organized into a statistical analysis program, SPSS Statistics v 29.0.2.0 (© IBM Corporation). Correlations were conducted on data gathered from Likert Scale questions, using Spearman test. Additionally, comprehensive non-numerical subjective data was …

Government Health Spending And Life Expectancy: Evidence From Cities And Districts In Indonesia, Kurnia Sari, Budi Hidayat, Amal Chalik Sjaaf, Mardiati Nadjib

Kesmas

Life expectancy is widely recognized as a fundamental indicator of population health, and its improvement is often linked to government health spending, particularly in decentralized health systems. This study aimed to investigate the relationship between local government health expenditures and life expectancy in decentralized Indonesia. Data from 492 cities and districts, spanning from 2015 to 2019, were analyzed using a two-way fixed effects regression model to control for time-invariant district characteristics and common temporal shocks. The findings indicated that a 10% increase per capita in government health expenditure was associated with a 0.01% increase in life expectancy. This association was …

Mortality And Heart Failure Exacerbations With Incretin-Mimetic Drugs For Weight Loss In Patients With Obesity-Related Heart Failure With Preserved Ejection Fraction, Leila Humphreys, Salvatore Carbone, Syed Imran Ahmed

Cardiovascular Research Symposium

Research has shown that incretin-mimetic agents approved and used for weight loss may help treat heart failure by improving their quality of life and functional capacity. Whether differences exist between these agents in the HFpEF population has not been tested before. Our study set out to see if these agents affected risk of all-cause mortality and further heart failure related hospitalizations in patients with obesity-related HFpEF and whether differences exist among them.

Staff Education On Perinatal Opioid Use Disorder, Mukisha Livingston Gunter

Walden Dissertations and Doctoral Studies

Perinatal Opioid Use Disorder (POUD) constitutes a significant public health issue with important ramifications for both mothers and their newborns. The gap in practice identified for this Doctor of Nursing Practice staff education project was the perinatal nurses’ lack of knowledge regarding POUD. The problem was the need for POUD education for the nurses. The practice focus questions were: Will there be a change in knowledge by perinatal nurses following the delivery of the education as shown by a pretest/posttest? Will the participants evaluate the education as having met the program objectives related to the curriculum presented? Guided by the …

Editorial: Endocrine Imbalances Of Mineral Ions And Vitamins In Chronic Disease Pathogenesis, Mor-Li Hartman, Hosam G. Abdelhady, Mohammed S. Razzaque

School of Medicine Publications

No abstract provided.

A Protective Role Of Src-1 Against Aging Associated Cognitive Decline, Hesong Liu, Yongjie Yang, Jonathan C Bean, Yang He, Hailan Liu, Rambabu Majji, Chen Liang, Nan Zhang, Meng Yu, Longlong Tu, Qingzhuo Liu, Yue Deng, Kristine M Conde, Na Yin, Mengjie Wang, Yongxiang Li, Junying Han, Sanika Vattakuzhiyil Jossy, Megan Elyse Burt, Hari Krishna Yalamanchili, Chunmei Wang

Duncan NRI Faculty and Staff Publications

Introduction: Research indicates a strong correlation between obesity and the risk of dementia, both are linked to steroid receptor coactivator-1 (SRC-1), a transcriptional coactivator.

Methods: We used RNA sequencing analysis (RNA-Seq) to investigate the transcriptome of SRC-1-KO mice, and identified S100 calcium-binding protein A6 (S100A6), an AD associated gene, as one target of SRC-1. We tested cognitive behaviors in SRC-1-KO mice and mice with a humanized SRC-1 mutation (SRC-1L1376P), and performed promoter luciferase assays on S100A6.

Results: Loss of SRC-1 caused alterations in gene signatures that are commonly associated with neurodegenerative diseases, including AD, and diminished the neural plasticity of …

Loss Of Dihydroceramide Desaturase Drives Neurodegeneration By Disrupting Endoplasmic Reticulum And Lipid Droplet Homeostasis In Glial Cells, Yuqing Zhu, Kevin Cho, Haluk Lacin, Yi Zhu, Jose T Dipaola, Beth A Wilson, Gary Patti, James B Skeath

2020-Current year OA Pubs

Dihydroceramide desaturases convert dihydroceramides to ceramides, the precursors of all complex sphingolipids. Reduction of DEGS1 dihydroceramide desaturase function causes pediatric neurodegenerative disorder hypomyelinating leukodystrophy-18 (HLD-18). We discovered that

Biosorption Of Crystal Violet Onto Fenugreek Seed Powder: Comprehensive Optimization Through Response Surface Methodology And Elucidation Of Dye Uptake Mechanism, Hasan M. Agha, Zaher Mundher Yaseen, Wafaa Raji Alfatlawi, Khansaa Al-Essa, Abdallah Reghioua, Hussein A. Kazem, Lee D. Wilson

AUIQ Complementary Biological System

This work investigates the efficacy of fenugreek seed powder (FSP), an agricultural product, as an economical and sustainable biosorbent for the extraction of crystal violet (CV) dye from aqueous environments. The biosorbent was analyzed using XRD, FTIR, and SEM-EDX, validating its amorphous structure, surface functional groups, and porous shape. Batch biosorption tests were adjusted utilizing a Box–Behnken design (BBD), incorporating three independent variables: FSP dose (0.02–0.1 g/100 mL), pH (4–10), and time (5–60 min). The model exhibited exceptional prediction accuracy (R² = 0.99, CV = 2.12%) and recognized all three variables as statistically significant (p < 0.05). The maximum CV removal attained was 91.8% efficiency at an FSP dose of 0.1 g/100 mL, pH 7, and a time of 60 minutes. FTIR examination indicated changes in the –OH, C=O, and C–O functional groups, signifying their participation in dye interaction, whilst SEM pictures validated dye deposition on the biosorbent surface. The biosorption process was ascribed to electrostatic forces, hydrogen bonding, π–π stacking, and pore filling. These findings underscore FSP as a viable, economical biosorbent for the removal of cationic dyes in wastewater treatment applications.

Pfkfb3 Activates Cad To Enhance De Novo Pyrimidine Synthesis For Cell Growth, Qingen Da, Yongfeng Cai, Qian Ma, Qiuhua Yang, Yapeng Cao, Yaqi Zhou, Dingwei Zhao, Zhiping Liu, Jiean Xu, Junming Quan, Liang Zhang, Rui Wang, Xuejun Jiang, Xiao Liu, Kunfu Ouyang, Zhen Han, Jikui Liu, Tao Wang, Chunxiang Zhang, Neal L Weintraub, David J R Fulton, Jun Zhao, Mei Hong, Zigang Li, Yuqing Huo

Faculty, Staff and Students Publications

Aerobic glycolysis, termed the Warburg effect, is one of the aberrant metabolic pathways in highly proliferating cells. Glycolysis provides glycolytic metabolites to support the generation of biomass, such as nucleotides, amino acids, and lipids. Research on the direct interactions between glycolysis and other metabolic pathways is an emerging field that has garnered significant interest. Phosphofructokinase-2/fructose-2,6-bisphosphatase 3 (PFKFB3) activates glycolysis by synthesizing fructose-2,6-bisphosphate (F2,6BP), which allosterically activates the rate-limiting enzyme 6-phosphofructo-1-kinase (PFK-1). In this study, we found that PFKFB3 directly interacts with and regulates the phosphorylation of carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD), the enzyme catalyzing the first three …

Partner Collective Impact Survey Final Evaluation Report, Courtney A. Fitzgerald, Theresa H. Cruz, Havana Maisano

Reports & Documents

The Healthy Here coalition, based in Bernalillo and Santa Fe Counties, brings together over 30 organizations working across four key areas: healthy eating, active living, family healthy weight, and vaccinations. In summer 2025, the coalition conducted a PARTNER Collective Impact Survey to evaluate its network structure, contributions, and effectiveness. The survey, completed by 29 organizations (87.9% response rate), provided insights into how member organizations collaborate, the resources they contribute, and how trust and value are perceived across the network.

Findings show that coalition members most frequently contributed community connections, content expertise, and information sharing, with Presbyterian Community Health and the …

Ifit3 Activation Significantly Contributes To Hiv-1-Associated Neurodegenerative Disorder-Mediated Neuroinflammation, Ranjit Kumar Das, Nirakar Sahoo, Deepa Roy, Chun Xu, Jose Galarza, Maria Camila Mejia Garza, Hansapani Rodrigo, Asim K. Duttaroy, Upal Roy

Health & Biomedical Sciences Faculty Publications

Introduction: The advent of effective combination antiretroviral therapy (cART) has significantly improved HIV-1 treatment, saving millions of lives. However, HAND remains a concern, particularly among aging individuals with HIV-1. The mechanisms underlying HAND are not well understood.

Methods: This study investigated the role of interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) and its upstream regulator, signal transducer, and activator of transcription 1 (STAT1), in HAND pathology. Using the SH-SY5Y neuroblastoma cell line and HIV-infected humanized mice, we examined the effects of the cART drugs, HIV Tat protein, and HIV-1 virus on STAT1 and IFIT3 expression.

Results: The results showed that …

Exploring Effective Weight Loss Interventions Among Three Fqhc-Based Clinical Programs In Central And Southern Illinois, Patrick Bruch, Oluwaseun Adeleke, Mia Lambert, Taylor Sutton, Georgia Luckey, Rebecca M. Hoffman Md,Msph

SIU Journal of Medical Science Scholarly Works

Background: Obesity affects 1 in 3 United States adults is associated with several chronic diseases. Disparities in obesity are seen in many vulnerable populations such as low-income groups, racial and ethnic minorities, and rural residents. Although primary care is often presented as a solution to the obesity crisis, management of obesity is complex and numerous challenges in helping patients achieve weight loss are still present. The U.S. Preventive Services Task Force recommended in 2018 that primary care providers screen for obesity and offer obese patients to intensive, multicomponent behavioral obesity treatment. However, there is little research involving primary care physicians …

The Association Between Malnutrition And Gingivitis Among Residents In St. Louis, Missouri, Alyssa Detrick

Walden Dissertations and Doctoral Studies

Malnutrition and gingivitis are common diagnoses in primary medical and dental care. The purpose of this quantitative study was to understand the association between malnutrition and gingivitis among residents in St. Louis, Missouri. The study was based on the social ecological model (SEM). The cross-sectional design involved secondary data (N = 2,553) from a Federally Qualified Health Center in St. Louis, Missouri that included de-identified patient demographic and diagnosis information of St. Louis City residents with a medical and dental visit in 2024. This study examined the relationship between malnutrition and gingivitis while controlling for ethnicity, preferred language, race, and …

Hepcidin, Incident Heart Failure, And Cardiac Dysfunction In Older Adults: The Aric Study, Iman A F Aboelsaad, Brian L Claggett, Victoria Lamberson, Pranav Dorbala, Kunihiro Matsushita, Pamela Lutsey, Bing Yu, Brandon W Lennep, Youssef M K Farag, Amil M Shah, Leo F Buckley

Faculty, Staff and Student Publications

Aims: Hepcidin regulates plasma and tissue iron levels. We studied the association of hepcidin levels with the risk of incident heart failure (HF) and cardiac dysfunction in older adults.

Methods and results: We included adults from the ongoing, longitudinal Atherosclerosis Risk in Communities (ARIC) study, who were free from prevalent anaemia and HF at Visit 5 (2011-13) and had available hepcidin and covariate data. Associations of plasma hepcidin levels with overall adjudicated incident HF, HF with reduced ejection fraction (HFrEF), and HF with preserved ejection fraction (HFpEF) were assessed using multivariable Cox proportional hazards regression models. Cross-sectional associations of hepcidin …

Family Healthy Weight Program: Smart Movestm Pilot Project Evaluation Report, Camille Velarde, Theresa H. Cruz Dr., Elena Martinez

Reports & Documents

The Smart Moves™ Family Healthy Weight Program is an evidence-based, family-centered intervention designed to address childhood overweight and obesity through nutrition education, physical activity, social-emotional learning, and caregiver engagement. In spring 2025, Presbyterian Community Health piloted Smart Moves™ in a South Valley community health clinic as part of the Healthy Here initiative, with evaluation conducted by the University of New Mexico Prevention Research Center.

The pilot, adapted from a 12-lesson curriculum to 8 core lessons plus orientation and celebration, included bilingual instruction, cooking in a teaching kitchen, and family-based incentives. Evaluation methods combined quantitative and qualitative data, including pre/post BMI …