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Addressing Sleep Health In The Fire Service: A Sleep Hygiene Education Program, Alyssa Elizabeth Neal May 2026

Addressing Sleep Health In The Fire Service: A Sleep Hygiene Education Program, Alyssa Elizabeth Neal

UNLV Theses, Dissertations, Professional Papers, and Capstones

This capstone project implemented an occupational therapy sleep hygiene program tailored to the unique occupational demands of Las Vegas Fire and Rescue (LVFR) firefighters. Guided by the Occupational Adaptation theory and the CALMS Framework, this project conceptualized sleep as a meaningful occupation essential to health, safety, and functional performance. The project’s aim was to assess the feasibility of a sleep hygiene program designed for the fire service using standardized measures, including the Sleep Hygiene Index. The methodology incorporated a structured educational session focused on educating firefighters on the importance of sleep, modifying routines and environments to support restorative sleep, implementing …


Movement-Based Program To Support Quality Of Life For Adults With Down Syndrome, Jillian Sanalila May 2026

Movement-Based Program To Support Quality Of Life For Adults With Down Syndrome, Jillian Sanalila

UNLV Theses, Dissertations, Professional Papers, and Capstones

This doctoral project focused on the development, implementation, and evaluation of a community-based movement program designed to support quality of life (QoL) among adults with Down syndrome and other intellectual and developmental disabilities at GiGi’s Playhouse Las Vegas. Adults with Down syndrome often experience significant health and participation disparities that negatively impact quality of life. These disparities include reduced physical activity, limited opportunities for social engagement, and barriers to engagement in meaningful occupations. Grounded in occupational therapy principles, this project introduced a structured intervention integrating dance, Pilates, and yoga to promote physical, emotional, and social well-being. A program development design …


Efficacy Of The Dorsal Application Of Kinesiotape For Carpal Tunnel Syndrome On Sleep, Alyanna San Pedro May 2026

Efficacy Of The Dorsal Application Of Kinesiotape For Carpal Tunnel Syndrome On Sleep, Alyanna San Pedro

UNLV Theses, Dissertations, Professional Papers, and Capstones

Carpal tunnel syndrome (CTS) is a common upper-extremity condition among university students who frequently engage in prolonged computer and device use. CTS symptoms, specifically in nocturnal pain, tingling, and numbness, often disrupt sleep quality, which can lead to negative effects on daytime functioning and participation in meaningful occupations. Despite growing interest in conservative management strategies, there is limited research on the potential role of kinesiotape (KT) in addressing sleep-related symptoms of CTS. This study aims to examine changes in sleep quality, nocturnal symptoms severity, and participation in meaningful activities in university students experiencing mild to moderate CTS symptoms. Participants were …


Examining Demographic And Contextual Differences In Stress-Related Sport Interference Among U.S. Collegiate Sport Participants, Heather Tran May 2026

Examining Demographic And Contextual Differences In Stress-Related Sport Interference Among U.S. Collegiate Sport Participants, Heather Tran

UNLV Theses, Dissertations, Professional Papers, and Capstones

Collegiate athletes experience a range of stressors that may interfere with sport performance; however less is known about how stress-related sport interference varies across demographic groups and contexts. Guided by the transactional model of stress and coping, this study examined differences in stress-related sport interference by gender, race/ethnicity, and year in school, as well as across situational contexts (training, competition, and life outside of sport). Data were drawn from a secondary dataset of 288 collegiate sport participants who completed the Sport Interference Checklist (SIC). Independent samples t-test and analyses of variance (ANOVA) were used to examined demographic differences, and a …


Examining The Effects Of Tailored Ergonomic Interventions On Reducing Musculoskeletal Disorders For Taxi Drivers, Amal Youssouf May 2026

Examining The Effects Of Tailored Ergonomic Interventions On Reducing Musculoskeletal Disorders For Taxi Drivers, Amal Youssouf

UNLV Theses, Dissertations, Professional Papers, and Capstones

Taxi drivers are frequently exposed to prolonged sitting, whole-body vibration, limited rest opportunities, and psychosocial stressors, placing them at increased risk for musculoskeletal disorders (MSDs). This can be mitigated with the use of ergonomics, which changes one's environment to match an individual's needs within the context and demands of the job. Although ergonomics is a recognized area of occupational therapy (OT) practice, current research is limited to office-based or computer-related settings, leaving a gap in OT-led ergonomic interventions tailored for professional drivers. This capstone project aimed to determine whether OT-based ergonomic strategies, along with an ergonomic checklist as a guideline …


College Of Fine Arts Outreach And Health Promotion For Injury Prevention: A Service Learning Project, Andrea Bejaran-Choto, Emily Horner, Marlene Quirarte, Shaye Robles, Dora Segura, Duc Tu, Trevor Williams May 2026

College Of Fine Arts Outreach And Health Promotion For Injury Prevention: A Service Learning Project, Andrea Bejaran-Choto, Emily Horner, Marlene Quirarte, Shaye Robles, Dora Segura, Duc Tu, Trevor Williams

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: This community-based academic initiative targeted a significant deficiency regarding rehabilitative care and wellness assets for Southern Nevada's fine arts practitioners. Despite possessing trauma frequency rates similar to those of collegiate-level athletes, this demographic lacks sufficient infrastructure for health support. The endeavor sought to bolster the University of Nevada, Las Vegas College of Fine Arts (CFA) and the regional performance art sector utilizing the UNLV College of Fine Arts Physical Therapy Clinic (CFA-PTC).

Description: The initiative focused on three essential objectives: (1) augmenting student consciousness and utilization of therapeutic care at the CFA-PTC, (2) broadening health-related guidance for the artistic …


Resilience Of Orthodontic Sealants Against Degradation And Microbial Adhesion: A Comparative Study, Michelle X. Cui May 2026

Resilience Of Orthodontic Sealants Against Degradation And Microbial Adhesion: A Comparative Study, Michelle X. Cui

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background:

White spot lesions are one of the most common complications encountered during orthodontic treatment. These lesions begin as demineralization of enamel around the appliance due to plaque buildup, resulting in compromised aesthetics. As they continue to develop, white spot lesions progress to cavitation, potentially threatening pulpal vitality, resulting in an increased financial burden for patients. Preventative strategies include patient education, consistent oral hygiene protocols, and the use of fluoride-releasing agents. Orthodontic sealants such as Opal® Seal™ (Ultradent) (OS) and L.E.D. Pro Seal® (Reliance) (PS) have been developed to release and recharge fluoride, thereby reducing the incidence of white spot …


An Occupation-Based Protocol For Mobile-Gaming Ergonomics, Lan Doan May 2026

An Occupation-Based Protocol For Mobile-Gaming Ergonomics, Lan Doan

UNLV Theses, Dissertations, Professional Papers, and Capstones

The increasing prevalence of mobile gaming has introduced unique ergonomic challenges that may contribute to musculoskeletal disorders (MSDs) and repetitive strain injuries (RSIs). The purpose of this feasibility study was to evaluate the practicality and preliminary effectiveness of an ergonomic protocol designed to improve posture, reduce pain, and maintain gaming performance among mobile gamers. A pre-post design was implemented with two participants aged 18–34 years. The six-week intervention included ergonomic education, postural training, scheduled breaks, and targeted stretching and strengthening exercises. Quantitative data on gaming performance using Call of Duty Mobile Scores, pain assessed through the Short-form McGill Pain Questionnaire …


Evaluating An Educational Intervention On Screen-Time And Behavior Change: A Pilot Study, Kayla L. Sweeney May 2026

Evaluating An Educational Intervention On Screen-Time And Behavior Change: A Pilot Study, Kayla L. Sweeney

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Excessive screen time among adolescents has been associated with negative health outcomes, including sleep disturbances, anxiety, and depression. Despite growing awareness, many parents lack sufficient understanding of these risks and their impact on adolescent well-being. This project evaluated whether a brief educational intervention improved parents’ knowledge of the health effects of excessive screen time. Methods: A pre-and post-survey design was used to assess changes in parents’ understanding following an educational video intervention. The educational intervention consisted of evidence-based content highlighting the impact of screen time on mental health and sleep. The survey measured knowledge, beliefs, behavioral intentions, and strategies …


Addressing Sexual Health For Older Veterans By Healthcare Providers: A Mixed Method Study, Andrew James White May 2026

Addressing Sexual Health For Older Veterans By Healthcare Providers: A Mixed Method Study, Andrew James White

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Older adults remain sexually active, yet sexual health is frequently under-discussed in healthcare settings, particularly within veteran populations. Sexual health is essential to overall quality of life, and prior studies have shown that older patients value these conversations. However, veterans often face unique factors such as military-related trauma, including military combat exposure and post-traumatic stress disorder, in addition to compounded stigma from these topics in regards to open discussions about sensitive health issues to their healthcare providers. This study is significant in its potential to uncover systemic, cultural, and interpersonal influences that shape these dynamics, with a particular emphasis …


Exploring Direct Support Professionals' (Dsps) Attitudes Regarding Trauma Informed Care And Its Impact On Turnover Intention, Lorraine D'Sylva-Lee May 2026

Exploring Direct Support Professionals' (Dsps) Attitudes Regarding Trauma Informed Care And Its Impact On Turnover Intention, Lorraine D'Sylva-Lee

Seton Hall University Dissertations and Theses (ETDs)

The relationship between Direct Support Professionals’ (DSPs’) attitudes toward trauma-informed care (TIC) and their turnover intention has remained empirically untested, despite DSPs’ exposure to primary and secondary trauma. An estimated 8.38 million Americans with intellectual and developmental disabilities (IDD) depend on this workforce, yet 2024 turnover rates reach 53.7%. This convergent mixed methods study examined TIC attitudes, turnover intention, and their relationship among 109 DSPs in IDD provider agencies in New Jersey. Grounded in the Theory of Planned Behavior (TPB), the cross-sectional design used the ARTIC-10, TIS-6, and two open-ended items. DSPs with more favorable TIC attitudes were significantly less …


Incivility In Nursing: The Experience Of Registered Nurses In The Emergency Department, Karen Voorhees May 2026

Incivility In Nursing: The Experience Of Registered Nurses In The Emergency Department, Karen Voorhees

Seton Hall University Dissertations and Theses (ETDs)

The American Association of Colleges of Nursing (AACN) predicts that due to the anticipated retirement of the “baby boomer” generation coupled with an expanded need for medical care across the United States, the need for nurses will expand 6% by 2032 (AACN, 2024). This need will be impeded by nurses leaving the profession due to feelings of a poor work environment, burnout and job dissatisfaction. Incivility in nursing has been shown to be a contributor to nurses leaving their current work environments or the profession of nursing entirely.

Incivility in nursing has roots in organizational psychology and has been shown …


Golden Steps: A Dance-Based Program To Improve Balance In Older Adults — A Feasibility And Acceptability Study, Ramyr Bognot, Sophia Botelho, Nolan Caberto, Lauren Valerio, Joshua Yu, Jason Zeidman May 2026

Golden Steps: A Dance-Based Program To Improve Balance In Older Adults — A Feasibility And Acceptability Study, Ramyr Bognot, Sophia Botelho, Nolan Caberto, Lauren Valerio, Joshua Yu, Jason Zeidman

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background

Falls are a leading cause of injury and loss of independence among older adults. Evidence-based programs such as Otago and Tai Ji Quan reduce fall risk, yet barriers to access and adherence remain. Dance-based interventions may offer a practical, enjoyable approach to engage older adults in balance training.

Purpose

This formative pilot study aimed to develop four dance routines grounded in evidence- based balance principles and evaluate their feasibility and acceptability among older adults, including factors influencing enjoyment and willingness to continue participation, to inform future clinical and community implementation.

Methods

Four routines (Polka, Country, Rockabilly, Salsa) were developed …


Effects Of A 12-Week Physical Therapy-Based Exercise Intervention On Gait In Adults With Down Syndrome, Samantha Betts, Stephen Kiraly, Paige Lucero, James Malabanan May 2026

Effects Of A 12-Week Physical Therapy-Based Exercise Intervention On Gait In Adults With Down Syndrome, Samantha Betts, Stephen Kiraly, Paige Lucero, James Malabanan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Individuals with Down Syndrome (Ds) frequently have sedentary lifestyles and Ds-specific physical impairments such as ligamentous laxity and hypotonia. These impairments often contribute to gait deviations that reduce the efficiency of ambulation. Purpose: The purpose of this study was to examine the effects of a 12-week exercise program on spatiotemporal characteristics of gait and kinematic variables at the hip, knee, and ankle in adults with Down syndrome (Ds). Methods: A randomized control trial of 40 participants was conducted with two groups: one group of adults with Ds who participated in a 12-week exercise program, and a control group who …


Evaluation Of Two Bioaerosol Sampling And Analysis Methods For The Collection Of Airborne Bacteria And Viruses, Elizabeth Detrick May 2026

Evaluation Of Two Bioaerosol Sampling And Analysis Methods For The Collection Of Airborne Bacteria And Viruses, Elizabeth Detrick

UNLV Theses, Dissertations, Professional Papers, and Capstones

Bioaerosols, defined as airborne particles of biological origin, include bacteria, fungi, viruses, and their byproducts. They are ubiquitous in both indoor and outdoor environments and can cause respiratory infections, allergic reactions, and toxin-mediated illnesses. Air sampling plays a vital role in bioaerosol monitoring by enabling the collection and analysis of airborne microorganisms to assess exposure risk and inform mitigation strategies. The objective of this study was to determine the relative collection efficiency of two air samplers, the MD8 Airscan, a filtration sampling method, and the SKC BioSampler, an impingement sampling method. Aerosolization tests were conducted in a controlled test chamber …


Efficacy Of Dorsal Application Kinesio® Tex Tape On Esports Performance, Charlie Moua May 2026

Efficacy Of Dorsal Application Kinesio® Tex Tape On Esports Performance, Charlie Moua

UNLV Theses, Dissertations, Professional Papers, and Capstones

This mixed-methods pilot study examined dorsal Kinesio® Tex Tape as a nonrestrictive occupational therapy intervention for adult PC gamers with carpal tunnel–type symptoms. As gaming participation increases, players may experience repetitive wrist and hand movements, prolonged postures, and high performance demands that contribute to discomfort, overuse symptoms, and reduced participation in meaningful gaming occupations. Four adult PC gamers completed five in-person sessions and were assigned to either dorsal wrist taping or sham scapular taping. Quantitative outcomes included the Boston Carpal Tunnel Questionnaire– Symptom Severity Scale, visual analog pain ratings, and Kovaak’s Aim Trainer performance scores and accuracy. Qualitative data were …


Exploring Lifestyle Habits Between Gamers And Non-Gamers: A Survey-Based Approach, Janavi Sathappan May 2026

Exploring Lifestyle Habits Between Gamers And Non-Gamers: A Survey-Based Approach, Janavi Sathappan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Video gaming is a prevalent and meaningful occupation for a growing number of young adults, yet its relationship to health behaviors is inconsistent and unclear in literature. This cross-sectional survey-based study examined the differences in nutritional pattens, sleep hygiene, and physical activity between self-identified gamers and non-gamers in a sample of young adults aged 18-34. Recruitment occurred primarily through the University of Nevada, Las Vegas and associated networks. Participants were asked to complete the Mini Eating Assessment Tool, Sleep Hygiene Index, and the International Physical Activity- Short Form. Data was analyzed using Mann-Whitney U tests and Pearson’s chi-square tests, and …


Impact Of Travel Time To Health Facilities On Perinatal Outcomes: A Systematic Review With Narrative Synthesis And Meta-Analysis, Sanam Roder-Dewan, Marwa Ramadan, Paul Ouma, Alexander Manu, Emelda A. Okiro, Natalie Strobel, Bibian N. Robert, Emily Odipo, Peter M. Macharia, Anthony Danso-Appiah, David C. Goodman, Queen Dube, Gagan Gupta, Hema Magge, Karen Edmond May 2026

Impact Of Travel Time To Health Facilities On Perinatal Outcomes: A Systematic Review With Narrative Synthesis And Meta-Analysis, Sanam Roder-Dewan, Marwa Ramadan, Paul Ouma, Alexander Manu, Emelda A. Okiro, Natalie Strobel, Bibian N. Robert, Emily Odipo, Peter M. Macharia, Anthony Danso-Appiah, David C. Goodman, Queen Dube, Gagan Gupta, Hema Magge, Karen Edmond

Research outputs 2022 to 2026

Background: Evidence-based global guidance on safe travel time for small or sick newborns who require transfer to health facilities after birth is lacking. A two-hour threshold is frequently cited in low- and middle-income countries (LMICs), while 30 minutes is commonly used in high-income countries (HICs). Although these thresholds are widely referenced, their empirical basis and consistency across levels of newborn care and journey types have not been systematically examined. This study synthesises the evidence linking travel time and perinatal outcomes. Methods: We conducted a systematic review with narrative synthesis and meta-analysis to assess the impact of travel time or distance …


Gut Dysbiosis And Microbial Metabolites In Atopic Dermatitis: Implications For Immune Regulation Along Gut-Skin Axis, Khushbakhat Alia, Hira Khan, Hamna Muzaffar, Nighat Perveen, Sara Alrashedi, Yusra Al Dhaheri, Yasir Waheed, Mohammed Tauqeer Alam, Muhammad Naseem, Khalid Muhammad May 2026

Gut Dysbiosis And Microbial Metabolites In Atopic Dermatitis: Implications For Immune Regulation Along Gut-Skin Axis, Khushbakhat Alia, Hira Khan, Hamna Muzaffar, Nighat Perveen, Sara Alrashedi, Yusra Al Dhaheri, Yasir Waheed, Mohammed Tauqeer Alam, Muhammad Naseem, Khalid Muhammad

All Works

Atopic dermatitis (AD) is a multifactorial skin disorder characterized by immune dysregulation, impaired epidermal barrier, and strong microbial imbalance. Although genetic susceptibility and environmental triggers are established AD drivers, growing evidence highlights the gut skin axis as an important but underexplored AD pathogenesis factor. Gut microbiota dysbiosis, loss of short-chain fatty acid (SCFA)-producing bacteria, and altered metabolite profiles, such as tryptophan derivatives and secondary bile acids, have been linked to systemic immune imbalance and skin inflammation. However, the precise mechanism by which gut microbial alterations influence cutaneous immunity remains unclear. This review synthesizes recent advances from clinical and experimental studies …


Neurodiversity Among Nurses: Consequences For Wellbeing And Burnout, Megan Pohlmann May 2026

Neurodiversity Among Nurses: Consequences For Wellbeing And Burnout, Megan Pohlmann

WUSM Theses and Dissertations – All Programs

Background/Introduction – Current research highlights three critical aspects of nurse wellbeing: the subjective personal perspective, multifaceted complexity, and variation across individuals. A particular gap in past research is a lack of understanding of how neurodivergence may impact nurses’ workplace wellbeing. Neurodiversity is the variation in human minds and neurocognitive functioning, and neurodivergence is the divergence from what society would consider the norm. Like wellbeing, it is difficult to capture, recognize, and define, which causes confusion among neurodivergent individuals and employers alike. With up to 20% of individuals displaying neurodivergent traits in the workplace, it is important to recognize that those …


Harnessing Mechanobiology Of Resident Stem Cells To Refine Cell Based Therapeutics, Dakota R. Kamm May 2026

Harnessing Mechanobiology Of Resident Stem Cells To Refine Cell Based Therapeutics, Dakota R. Kamm

WUSM Theses and Dissertations – All Programs

Mesenchymal stem cells (MSCs) are resident cells residing with many adult tissues such as adipose tissue and bone marrow that have the potency for multiple lineage differentiation as well as the capacity to secrete a litany of beneficial factors to maintain homeostasis and promote tissue repair. Since 1995, MSCs have been used therapeutically to treat a variety of conditions from osteoarthritis to heart disease to muscle pathologies. Great leaps have been made in improving MSC-based therapies through optimization of culture methods and select enrichment of cellular subpopulations. More recently, the physical microenvironment of tissue in vivo and culture conditions in …


Quantification Of Sarm1 Nadase Activity In Human Peripheral Blood Mononuclear Cells, Lila F Dabill, Ivana R Shen, Jennifer M Brazill, Alicia Neiner, Yo Sasaki, Erica L Scheller May 2026

Quantification Of Sarm1 Nadase Activity In Human Peripheral Blood Mononuclear Cells, Lila F Dabill, Ivana R Shen, Jennifer M Brazill, Alicia Neiner, Yo Sasaki, Erica L Scheller

2020-Current year OA Pubs

SARM1 (sterile α and TIR motif-containing protein-1) is an NADase enzyme that serves as the central executioner of Wallerian axon degeneration. Given this, SARM1 is of high interest as a candidate therapeutic target, and SARM1 inhibitors are currently in clinical trials for treatment of neurodegeneration. Beyond neuroscience, emerging studies reveal that SARM1 may also drive aspects of bone fragility, liver pathology, adipose expansion, and insulin resistance in metabolic disease. However, we lack methods to quantify SARM1 activation in humans to better define patients at high risk of SARM1-mediated tissue damage. Unlike neurons, peripheral blood mononuclear cells (PBMCs) represent an easily …


Male Pelvic Health In Saudi Arabia: Knowledge–Practice Gap In Pelvic Floor Muscle Exercises And Implications For Preventive Physiotherapy And Health Policy, Wael A. S. Alghamdi May 2026

Male Pelvic Health In Saudi Arabia: Knowledge–Practice Gap In Pelvic Floor Muscle Exercises And Implications For Preventive Physiotherapy And Health Policy, Wael A. S. Alghamdi

Saudi Medical Journal

No abstract provided.


Demographic Profiles, Clinical Characteristics, And Meteorological Context Of Heat-Related Illnesses Among Hajj Pilgrims In 2023, Ghadah Alsaleh, Majed Alsalamah, Fahad Alamri, Fatemah Alsaleh, Anas Khan May 2026

Demographic Profiles, Clinical Characteristics, And Meteorological Context Of Heat-Related Illnesses Among Hajj Pilgrims In 2023, Ghadah Alsaleh, Majed Alsalamah, Fahad Alamri, Fatemah Alsaleh, Anas Khan

Saudi Medical Journal

Objective: To describe the demographic profiles, clinical characteristics, and meteorological context of heat-related illnesses among Hajj pilgrims in 2023.

Methods: A retrospective cross-sectional study was conducted using data from 1,129 pilgrims diagnosed with HRIs across healthcare facilities in Mecca, Mina, and Arafat. Demographic and clinical data were extracted from the Hajj Health Information System, while temperature, humidity, wind speed, and rainfall records were obtained from the National Center for Meteorology.

Results: Heat exhaustion (48.2%) and heatstroke (37.4%) were the most common diagnoses, with 24.9% of the cases requiring hospitalization. Males represented 55.4% of cases and accounted for 51.2% of …


Obesity's Role In Stroke Incidence Among Smokers: An Assessment Of Confounding, Interaction, And Mediation Effects, Saeed Awad M. Alqahtani, Moutasem Salih Aboonq May 2026

Obesity's Role In Stroke Incidence Among Smokers: An Assessment Of Confounding, Interaction, And Mediation Effects, Saeed Awad M. Alqahtani, Moutasem Salih Aboonq

Saudi Medical Journal

Objectives: To examine the association between body mass index (BMI) category and history of stroke among current smokers, while assessing potential confounding, effect modification by age, and mediation by cardiovascular comorbidities. Methods: Data were analyzed from 53,939 current adult smokers participating in the 2021 Behavioral Risk Factor Surveillance System (BRFSS). Survey-weighted logistic regression estimated the association between BMI categories (underweight, normal, overweight, obese) and self-reported stroke history. The study assessed multicollinearity and adjusted for sociodemographic and health variables. Interaction terms were tested to evaluate effect modification by age, and exploratory decomposition analysis was used to assess mediation by conditions such …


Prevalence And Antimicrobial Susceptibility Patterns Of Nosocomial Bacteria Across Different Units At King Faisal Complex Hospital, Taif, Kingdom Of Saudi Arabia, Nahed Hawsawi, Renad N. Al-Jaiud, Layal L. Khyyat, Kholoud Alsulimany, Manhal Shabat May 2026

Prevalence And Antimicrobial Susceptibility Patterns Of Nosocomial Bacteria Across Different Units At King Faisal Complex Hospital, Taif, Kingdom Of Saudi Arabia, Nahed Hawsawi, Renad N. Al-Jaiud, Layal L. Khyyat, Kholoud Alsulimany, Manhal Shabat

Saudi Medical Journal

Objectives: Nosocomial infections significantly impact patient morbidity, mortality, and healthcare costs. To determine the prevalence, bacteriological profiles, antimicrobial susceptibility patterns, and resistance distribution of pathogens causing nosocomial infections at King Faisal Medical Complex, Taif, Kingdom of Saudi Arabia. Methods: This cross-sectional study was conducted between September 2023 and March 2024 at different hospital units following ethical approval. Samples (n = 667) were collected from patients (both genders; all ages) exhibiting infection symptoms ≥ 48 h post-admission and pre-antibiotic administration. Bacterial identification involved culture, Gram staining, and biochemical tests. Antimicrobial susceptibility was tested using the Phoenix100 system. Results: Of 667 patients, …


Barriers And Bridges: Exploring Factors That Shape Mental Health Service Utilization In Rural America, Margaret Wiwuga May 2026

Barriers And Bridges: Exploring Factors That Shape Mental Health Service Utilization In Rural America, Margaret Wiwuga

Educational Specialist, 2020-current

Despite disproportionately higher suicide mortality rates and comparable prevalence of mental illness across urban and rural communities in the United States, rural populations across the nation experience significantly lower access to and utilization of mental health services, naturally leading to worse comprehensive outcomes. This literature review examines multifaceted factors shaping mental health service use in rural America, taking note of both barrier and enabling factors that impede or enable these unique populations’ willingness and ability to access and use mental health services. Ten articles published prior to September 9, 2025, were selected from the James Madison University Libraries’ Psychology and …


Black Maternal Mental Health: Counseling Considerations For Prenatal Depression And Anxiety, Morgan Renee Williams May 2026

Black Maternal Mental Health: Counseling Considerations For Prenatal Depression And Anxiety, Morgan Renee Williams

Educational Specialist, 2020-current

The maternal mortality rate of Black women in the United States is four times higher than white women (Centers for Disease Control and Prevention, 2020). The CDC defines a maternal death as “the death of a woman while pregnant or within 42 days of termination of pregnancy… but not from accidental or incidental causes” (Centers for Disease Control and Prevention, 2024, para. 1). This statistic is a consequence of the inequality within and outside of the American healthcare system (National Academies of Sciences, Engineering, and Medicine, 2020). For the purposes of this research, Black women are defined as any women …


What’S Behind The Mask: The Diagnostic Divide In The Female Autism Phenotype, Shelley Gies Alston May 2026

What’S Behind The Mask: The Diagnostic Divide In The Female Autism Phenotype, Shelley Gies Alston

Educational Specialist, 2020-current

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by differences in social communication and restrictive, repetitive behaviors; however, women are diagnosed at significantly lower rates than men. This study examined whether DSM-5-TR diagnostic practices may contribute to the underdiagnosis and delayed identification of ASD in individuals assigned female at birth (AFAB), with attention to masking behaviors, gendered social expectations, and clinician interpretation of symptoms. Grounded in the Female Autism Phenotype (FAP), a retrospective mixed-methods study surveyed 12 AFAB individuals aged 18–24 who self-identified or were formally diagnosed with ASD. Participants completed a 44-item online survey including Likert-scale and open-ended …


Thrombin-Induced Myofibroblast Differentiation Is Regulated By Myocardin And Novel Effector Genes In Ipf Fibroblasts, Christiana Okeke May 2026

Thrombin-Induced Myofibroblast Differentiation Is Regulated By Myocardin And Novel Effector Genes In Ipf Fibroblasts, Christiana Okeke

Biotechnology Theses

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by fibroblast activation, excessive extracellular matrix (ECM) deposition, and irreversible respiratory decline. In this study, we investigated the role of myocardin and its downstream effectors, RGS5, DLGAP5, and TAGLN, in thrombin-induced myofibroblast differentiation and ECM remodeling using primary human IPF fibroblasts. Myocardin knockdown significantly attenuated thrombin-induced expression of profibrotic genes, including FN1, COL1A1, PAI-1, ACTA2, and CNN1, as well as the novel effectors RGS5, DLGAP5, and TAGLN, confirming myocardin as a central regulator of fibrotic signaling. Silencing RGS5 produced minimal effects on gene and protein expression despite minor downward …