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What's Happening: January 28, 1981, Maine Medical Center Jan 1981

What's Happening: January 28, 1981, Maine Medical Center

What's Happening

No abstract provided.


The Gay Nineties: Oscar Wilde Reconsidered, Frederick J. Spencer Jan 1981

The Gay Nineties: Oscar Wilde Reconsidered, Frederick J. Spencer

MCV/Q, Medical College of Virginia Quarterly

Sex and hypocrisy have always been bedmates, but never more than in Victorian England. In the “Gay Nineties” promiscuity was widely accepted in all social classes, although the aristocracy hid its lust behind a strict code of propriety. Country house parties catered to infidelities with the approval of the Prince of Wales, himself a notorious womanizer.


Biomedical Research And Animal Welfare: Traditional Viewpoints And Future Directions, Franklin M. Loew Jan 1981

Biomedical Research And Animal Welfare: Traditional Viewpoints And Future Directions, Franklin M. Loew

Experimentation Collection

It has been twenty years since C.P. Snow first presented the concept of "The Two Cultures"; referring to the "culture" of scientists and the "culture" of literary intellectuals (mainly writers), Snow said (1969):

... constantly I felt I was moving among two groups- comparable in intelligence, identical in race, not grossly different in social origin, earning about the same incomes, who had almost ceased to communicate at all, who in intellectual, moral and psychological climate had so little in common ...

In some ways, "Two Cultures" goes far to characterize the current state of affairs surrounding those whose scientific endeavors …


Mcv/Q, Medical College Of Virginia Quarterly, Vol. 15 No. 3 Jan 1981

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 15 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.


Football Media Guide 1981, Indiana State University Jan 1981

Football Media Guide 1981, Indiana State University

Intercollegiate Athletics

No abstract provided.


1981 Transactions, American Dental Association Jan 1981

1981 Transactions, American Dental Association

ADA Transactions

This item is part of the Transactions of the ADA, a serial publication of the annual activities of the ADA House of Delegates (HOD)/Board of Trustees (BOT). It is from the Transactions section, one of three subtitles that make up the full publication. Generally, the ADA Transactions are published in multiple volumes throughout the year. Pages from the Annual Reports and the Transactions are numbered consecutively (e.g. Annual Reports volume ends pg. 500 and Transactions volume starts at pg. 501). NOTE: All three subtitles are collectively known as the Transactions of the ADA or, alternatively, the ADA Transactions. Transactions refers …


Kronos [1981], State University Of New York At Stony Brook, School Of Medicine Jan 1981

Kronos [1981], State University Of New York At Stony Brook, School Of Medicine

Kronos (School of Medicine)

This edition of Kronos, published in 1981, is the official yearbook of the State University of New York at Stony Brook, School of Medicine. Hard-bound.


Role Of The Arachidonic Acid Metabolites, Thromboxane A2 And Prostacyclin, In Shock Induced By Intraabdominal Sepsis, Robert Raymond Butler Jan 1981

Role Of The Arachidonic Acid Metabolites, Thromboxane A2 And Prostacyclin, In Shock Induced By Intraabdominal Sepsis, Robert Raymond Butler

MUSC Theses and Dissertations

A rat fecal peritonitis model of acute intraabdominal sepsis was investigated in order to evaluate the potential role of arachidonic acid metabolites in septic shock. Immunoreactive (i) Thromboxane (Tx) B2, the stable metabolite of TXA2' and i6-keto-PGF1α, the stable metabolite of prostacyclin, were measured by radioimmuonassay. plasma levels of iTXB2 rapidly increased from non-detectable (ND< 200 pg/ml) to 1,066 -/+ 194 pg/ml (N=14) 1 hour after feces injection. iTxB2 then increased to 1,695 -/+ 218 pg/ml (N=16) at 4 hours and remained unchanged through 6 hours. Plasma i6-keto-PGF1α increased from ND to 3,777 -/+ 414 pg/ml (N=16) at 1 hour. Four hours after feces, i6-keto-PGF1α levels rose to 6,945 -/+ 732 pg/ml (N=16) then continued to rise to 9,465 -/+ 792 pg/ml (N=7) at 6 hours. Either essential fatty acid deficiency (arachidonic acid depletion) or indomethacin pretreatment (cyclooxygenase inhibition) significantly decreased (P< 0.01) the elevations of plasma iTxB2 and i6-keto-PGF1α associated with fecal peritonitis. Thrombocytopenia occurred within 6 hours after injection of feces and was significantly improved (P< 0.05) by indomethacin. Elevated fibrin degradation products at 6 hours (18 -/+ 3 µg/ml) were significantly reduced in essential fatty acid deficient (7 -/+ 2 µg/ml; P< 0.05) and indomethacin treated (4 -/+ 0.7 µg/ml; P< 0.01) rats. Survival time (8.6 -/+ 0.2 hours) was significantly enhanced by essential fatty acid deficiency (10.2 -/+ 0.4 hrs; P< 0.01) or indomethacin pretreatment (13.3 -/+ 0.6 hrs; P< 0.01). These studies show that fecal peritonitis is associated with increased synthesis of thromboxane A2 and prostacyclin and suggest that these arachidonic acid metabolites may play a role in the pathophysiology of septic shock. To evaluate the pathogenic role of thromboxane (Tx) and prostacyclin (PGI2) in septic shock, the protective efficacy of the Tx synthetase inhibitor, 7(l-imidazolyl) heptanoic acid (7-IHA) and the cyclooxygenase inhibitor, ibuprofen, were assessed during fecal peritonitis in the rat. 7-IHA (60 mg/kg) administered ip 30 minutes prior to feces significantly reduced the plasma level of iTxB2 to ND (P< 0.01) at 1 hour and to 508 -/+ 56 pg/ml (P< 0.01) at 4 hours after injection of feces. In contrast, the levels of i6-keto-PGF1α, the stable metabolite of PGI2 were significantly elevated by 7-IHA pretreatment from septic control levels to 5,185 -/+ 467 pg/ml (P< 0.05) at 1 hour. Plasma i6-keto-PGF1α at 4 hours in 7-IHA treated rats (5,503 -/+ 665 pg/ml) was not different from untreated controls. Ibuprofen (5 mg/kg) administered ip 30 minutes prior to feces significantly decreased both iTxB2 and i6-keto-PGF1α plasma levels to 729 -/+ 99 pg/ml and 1,327 -/+ 251 pg/ml, respectively (P< 0.05) at 4 hours. Survival associated with fecal peritonitis was not altered by 7-IGA pretreatment, but was significantly improved (P< 0.05) in ibuprofen treated rates. Fibrin degradation products were also significantly decreased (P< 0.05) by 7-IHA pretreatment. These results suggest that TxA2 may contribute to the coagulopathies seen in septic shock and that PGI2 may be associated with terminal pathophysiologic events. The final phase of this project investigated the possible synergistic benefit between an antibiotic, gentamicin (GENT), and reduction of arachidonic acid metabolism by pre-administration of indomethacin (INDO) or essential fatty acid (EFA) deficiency. GENT significantly increased mean survival time to 23.8 -/+ 2.6 hours (N=16; P< 0.01). GENT + INDO or GENT + EFA deficiency further improved mean survival time and produced long term survivals (>48 hrs) of 35% (N=17) and 30% (N=7) respectively (P< 0.01 compared to GENT). GENT pretreatment did not significantly alter plasma iTxB2 levels, however, it selectively decreased i6-keto-PGF1α. For example, i6-keto-PGF1α decreased from 9,465 -/+ 792 pg/ml (N=7) to 2,096 -/+ 1174 pg/ml (N=5; P< 0.01) at 6 hours after induction of fecal peritonitis. GENT + INDO pretreatment significantly decreased both iTxB2 and i6-keto-PGF1α to ND (P< 0.01). Pretreatment with GENT alone did not reduce fibrin degradation products. These findings are consistent with the concept that TxA2 may play a role in consumptive coagulopathies and PGI2 may be associated with the terminal hypotension seen during septic shock. The effect of GENT on TxA2 and PGI2 production was investigated further. GENT had no observable effect on in vitro endotoxin stimulated production of these arachidonic acid metabolites by cultured rat peritoneal macrophages. GENT significantly reduced the plasma levels of iTxB2 and i6-keto-PGF1α during endotoxin induced shock in rats. These observations support a complex interaction of bacteria, endotoxin, host tissues, and gentamicin with the possible involvement of undescribed mediated factors.


An Analysis Of The Needs Of Re-Entry Nurses As Perceived By Re-Entry Nurses, Nurse Educators, And Nurse Administrators, Jean Phyllis Ruxton Jan 1981

An Analysis Of The Needs Of Re-Entry Nurses As Perceived By Re-Entry Nurses, Nurse Educators, And Nurse Administrators, Jean Phyllis Ruxton

University of the Pacific Theses and Dissertations

Purpose. The purpose of this study was to determine if differences existed in the perceptions of re-entry nurses, nurse educators, and nurse administrators with regard to the needs of women who wish to become re-employed in the nursing field. Specific barriers to re-entry and perceived needs in terms of skills and knowledge were examined. Procedure. The sample for the study included inactive nurses, nurse educators and nurse administrators from 13 counties within California. The inactive nurse (re-entry) group was selected from the rosters of three continuing education programs. The nurse educator and nurse administrator groups were randomly selected from a …


A Concurrent And Retrospective Evaluation Of The Effects Of Intrinsic And Extrinsic Motivating Factors On Nurse Performance In Home Health Care Settings., Marcia Kay Stanhope Jan 1981

A Concurrent And Retrospective Evaluation Of The Effects Of Intrinsic And Extrinsic Motivating Factors On Nurse Performance In Home Health Care Settings., Marcia Kay Stanhope

All ETDs from UAB

No abstract provided.


Baseball Media Guide 1981, Indiana State University Jan 1981

Baseball Media Guide 1981, Indiana State University

Intercollegiate Athletics

No abstract provided.


Systems Approach To St. Louis State Hospital's Referral Program, Reza Vahidi Jan 1981

Systems Approach To St. Louis State Hospital's Referral Program, Reza Vahidi

Theses

This thesis presents a systems approach to analyzing and redesigning referral and billing processes at St. Louis State Hospital in Missouri. Recognizing the growing complexity of hospital operations, the study applies systems theory to evaluate inefficiencies in the hospital’s referral program, particularly in its interactions with external agencies and community physicians. The hospital historically relied on manual procedures and fragmented communication methods that contributed to delays, inaccuracies, and underutilization of available resources.

The study examines the referral workflow from intake to admission, identifying systemic bottlenecks and proposing structured changes to improve coordination. Emphasis is placed on streamlining communication between hospital …


Synthesis And Biological Evaluation Of Sparsomycin Analogues, Scherer Preston Sanders Jan 1981

Synthesis And Biological Evaluation Of Sparsomycin Analogues, Scherer Preston Sanders

Theses and Dissertations

In 1962, Owen, Dietz, and Camiener reported the isolation of a new antitumor antibiotic from the culture filtrate of Streptomyces sparsogenes. The structure of the crystalline antibiotic, named sparsomycin, remained elusive until 1970, when Wiley and MacKellar reported results of spectroscopic and degradation studies which elucidated the structure. In addition to the molecular structure, investigators have examined the mechanism of action, toxicity, and related analogues, striving to establish sparsomycin or a synthetic analogue's usefulness as an effective chemotherapeutic agent.

The initial pharmacological evaluation of sparsomycin revealed it possessed activity against KB human epidermoid carcinoma cells, a variety of gram-negative and …


1981 Annual Reports And Resolutions, American Dental Association Jan 1981

1981 Annual Reports And Resolutions, American Dental Association

ADA Transactions

This item is part of the Annual Reports and Resolutions subtitle of the ADA Transactions, a serial publication of the annual activities of the ADA House of Delegates (HOD)/Board of Trustees (BOT) made up of three separate subtitles: Annual Reports and Resolutions, Supplements, and Transactions. Generally, the ADA Transactions are published in multiple volumes throughout the year. Older versions include reports from all departments as subsections, while more recent versions include only those of councils, commissions, and committees.


A Simulated Diet Interview For Use In Home Economics 306, Methods Of Home Economics Education, Patricia G. Shevac Jan 1981

A Simulated Diet Interview For Use In Home Economics 306, Methods Of Home Economics Education, Patricia G. Shevac

Theses, Dissertations and Capstones

The necessity for nutrition education of the patient is becoming increasingly important in the health care system. This kind of education can aid the patient to select and practice a more desirable nutritional behavior in order to produce a favorable change in his health status. The dietitian's role in health care education is the application of nutritional knowledge to the individual situation of the patient. A dietitian must first establish rapport with the patient through verbal and non-verbal communication. He or she must be able to understand others' feelings and be warm, friendly, and put the patient at ease. The …


J Am Coll Dent 1981 48 3 Jan 1981

J Am Coll Dent 1981 48 3

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.


Men's Basketball Media Guide 1981-1982, Indiana State University Jan 1981

Men's Basketball Media Guide 1981-1982, Indiana State University

Intercollegiate Athletics

No abstract provided.


Women's Basketball Media Guide 1981-1982, Indiana State University Jan 1981

Women's Basketball Media Guide 1981-1982, Indiana State University

Intercollegiate Athletics

No abstract provided.


Some Observations On The Development Of Pharmacy And Recommendations For Improving The Allocation Of Resources At St. Joseph's Hospital, Ivy Ann D. Lee-Sharpe Jan 1981

Some Observations On The Development Of Pharmacy And Recommendations For Improving The Allocation Of Resources At St. Joseph's Hospital, Ivy Ann D. Lee-Sharpe

Theses

It is the intent of this paper to trace the developmental history of pharmacy alluding to the profession as an integral part of medicine when treatment was simple, magically connected and filled with superstitions. It separated when medical knowledge expanded, technology advanced and regulations formalized pharmacy. Social and environmental factors established the needs for specialists to handle, compound, prepare and dispense drugs and medicines. The institutionalization of care and the entrance of the pharmacists in these institutions were influential in this separation and will be discussed. Although formally separated, pharmacy stayed intimately linked with medicine in literature and formal education …


In Vitro Percutaneous Penetration Of Methotrexate, Rajaram Vaidyanathan Jan 1981

In Vitro Percutaneous Penetration Of Methotrexate, Rajaram Vaidyanathan

University of the Pacific Theses and Dissertations

This research project was designed to investigate the effects of various physical and chemical parameters on percutaneous penetration of methotrexate. The potential of propylene glycol in water as a vehicle for topical delivery of methotrexate has been examined. A detailed examination of solubility, partition coefficient and pH parameters in the range of 2 to 6 pH units has been conducted with the goal of correlating their effects on skin penetration of methotrexate. The importance of physiochemical parameters such as solubility and partition coefficient and their aid in the development of a suitable delivery system for topical application has been explained. …


Virginia Dental Journal (Vol. 58, No. 6, 1981) Jan 1981

Virginia Dental Journal (Vol. 58, No. 6, 1981)

Virginia Dental Journal

No abstract provided.


Jefferson Alumni Bulletin – Volume Xxx, Number 2, Winter 1981 Jan 1981

Jefferson Alumni Bulletin – Volume Xxx, Number 2, Winter 1981

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXX, Number 2, Winter 1981

Diverse specialties harmonize, Page 2

The Navstar: a Pre-Columbian crossing, Page 8

President Cleveland’s lesion: new evidence uncovered, Page 15

Class notes, Page 23


The Effects Of Tissue Culture Medium (T199) On Perichondrium Of The Mandibular Condyle In Rabbits, Augustin Lopez Oteo Jan 1981

The Effects Of Tissue Culture Medium (T199) On Perichondrium Of The Mandibular Condyle In Rabbits, Augustin Lopez Oteo

Master's Theses

No abstract provided.


The Effect Of Local Tetracycline Therapy On The Subgingival Microflora And Various Clinical Parameters In Juvenile Periodontitis, Frank Anthony Riccoboni Jan 1981

The Effect Of Local Tetracycline Therapy On The Subgingival Microflora And Various Clinical Parameters In Juvenile Periodontitis, Frank Anthony Riccoboni

Master's Theses

No abstract provided.


The Effects Of Occlusal Trauma On Periapical Healing Following Endodontic Therapy In The Rhesus Monkey, Dennis Mckay Byrne Jan 1981

The Effects Of Occlusal Trauma On Periapical Healing Following Endodontic Therapy In The Rhesus Monkey, Dennis Mckay Byrne

Master's Theses

No abstract provided.


The Effects Of Achromycin V (Tetracycline) On The Percentage Anaerobic, Facultative And Tetracycline-Resistant Organisms, And On Selected Clinical Parameters In Advanced Periodontal Disease, Eric J. Coontz Jan 1981

The Effects Of Achromycin V (Tetracycline) On The Percentage Anaerobic, Facultative And Tetracycline-Resistant Organisms, And On Selected Clinical Parameters In Advanced Periodontal Disease, Eric J. Coontz

Master's Theses

No abstract provided.


A Comparative Radiographic And Histologic Analysis Of Experimentally Produced Pulpo-Periapical Lesions In The Dog, Lance W. Crawford Jan 1981

A Comparative Radiographic And Histologic Analysis Of Experimentally Produced Pulpo-Periapical Lesions In The Dog, Lance W. Crawford

Master's Theses

No abstract provided.


Identification Of Igg, Igm, C1q And C4 On Bacterial Plaque Organisms In Periodontitis, Jacobo Nazari Chisikovsky Jan 1981

Identification Of Igg, Igm, C1q And C4 On Bacterial Plaque Organisms In Periodontitis, Jacobo Nazari Chisikovsky

Master's Theses

No abstract provided.


An Analysis Of The Effect Of Immediate Corrective Feedback Administered As A Study Aid To Undergraduate Medical Technology Students, Constance Anne Bak Jan 1981

An Analysis Of The Effect Of Immediate Corrective Feedback Administered As A Study Aid To Undergraduate Medical Technology Students, Constance Anne Bak

Theses and Dissertations

Twenty-six undergraduate medical technology students at Virginia Commonwealth University were provided with a Hemestasis Study Guide to use during this unit and in preparing for an exam in this area. The study guide contained fifty objective-related questions in multiple-choice format. Answers were printed in latent image and included positive reinforcement for correct selections and remediation for incorrect ones. Thus the student received immediate feedback concerning his response to each question.

An examination grade continuum was plotted for this class utilizing all exam grades in the Hematology course. A similar continuum was plotted for each of the three previous classes. (These …


Release Of Cortisol From Propylene Glycol Monostearate--Ethoxylated Stearyl Alcohol Films, Conway Ko-Huri Chou Jan 1981

Release Of Cortisol From Propylene Glycol Monostearate--Ethoxylated Stearyl Alcohol Films, Conway Ko-Huri Chou

University of the Pacific Theses and Dissertations

In the present study, propylene glycol monostearate (PGM), ethoxylated stearyl alcohol (ESA) and combination thereof have been investigated for their film-forming potential. The wettability, strength, and integrity of the films were evaluated by measuring the contact angles and modulus of elasticity. The films of mixed composition had smaller contact angles than the films of either component. The modulus of elasticity of all films tested was in the range of 0.19 - 0.40 Kg/cm2. A series of experiments were conducted in vitro to study the effect of changes in film composition, drug concentration and rate of agitation on cortisol …