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Articles 1831 - 1860 of 57448
Full-Text Articles in Entire DC Network
Small-Molecule Correlates Of Infection Precede Infection Diagnosis In Breast Implant Reconstruction Patients, John A. Wildenthal, Margaret A. Olsen, Hung D. Tran, John I. Robinson, Terence M. Myckatyn, David K. Warren, Keith E. Brandt, Marissa M. Tenenbaum, Joani M. Christensen, Thomas H. Tung, Justin M. Sacks, Rachel A. Anolik, Katelin B. Nickel, Hideji Fujiwara, Peter J. Mucha, Jeffrey P. Henderson
Small-Molecule Correlates Of Infection Precede Infection Diagnosis In Breast Implant Reconstruction Patients, John A. Wildenthal, Margaret A. Olsen, Hung D. Tran, John I. Robinson, Terence M. Myckatyn, David K. Warren, Keith E. Brandt, Marissa M. Tenenbaum, Joani M. Christensen, Thomas H. Tung, Justin M. Sacks, Rachel A. Anolik, Katelin B. Nickel, Hideji Fujiwara, Peter J. Mucha, Jeffrey P. Henderson
2020-Current year OA Pubs
BACKGROUNDInfection is an important complication of implanted devices and prosthetics. Identifying infections sufficiently early to salvage implants and avoid reconstructive failure is a persistent medical challenge.METHODSTwo cohorts of women 21 years and older undergoing breast implant reconstruction were recruited. Seroma fluid (82 breasts, 70 patients) was collected upon implant removal for infectious or noninfectious causes. Postimplantation drain fluid (100 samples, 44 breasts, 32 patients) was collected at routine visits prior to implant removal. A liquid chromatography/mass spectrometry-based metabolomic approach was used to identify infection correlates.RESULTSIn seroma fluid specimens, infection was associated with a diverse set of small molecules, including acetylated …
Intouch Week Of February 16, 2026, New York Medical College
Intouch Week Of February 16, 2026, New York Medical College
InTouch
- HeLa Conference Explores Ethics, Equity, and Innovation in a Changing Health Care Landscape
- Kupersmith Lecture Explores Federal Tax Incentives for Living Kidney Donation: Ethical, Economic, and Halachic Considerations
- Medical Students Celebrate in Style at Annual NYMC Formal
- Faculty Spotlight: From Pupil to Professor: Randy Goldberg, M.D. '97, M.P.H. '13, FACP, FHM
Automated Quantification Of Movement Qualities In The Human Upper Extremity After Stroke Using A Wearable Robot., Yoon No Gregory Hong, Kyoungsoon Kim, Sheng Li, Marcia K O'Malley, Ashish D Deshpande, Jinsook Roh
Automated Quantification Of Movement Qualities In The Human Upper Extremity After Stroke Using A Wearable Robot., Yoon No Gregory Hong, Kyoungsoon Kim, Sheng Li, Marcia K O'Malley, Ashish D Deshpande, Jinsook Roh
Faculty, Staff and Student Publications
Background: Stroke is a leading cause of long-term adult disability, with approximately 80% of survivors experiencing upper extremity (UE) motor impairments. Conventional tools like the Fugl-Meyer Assessment (FMA) are widely used but limited by ordinal scales and subjective visual observation. While wearable robotics offer high-resolution data, their clinical translation is hindered by a lack of standardized protocols and limited interpretability for clinical decision-making.
Objective: This study aimed to develop an objective, standardized, and clinically interpretable method to quantify UE motor qualities by integrating wearable robotic technology with traditional clinical assessment tasks.
Methods: Ten healthy individuals and ten stroke survivors performed …
Emotional Intelligence And Problem-Solving Correlations And Impact On Employability: A Case Study From The Uae, Ganka Ivanova, Rakan Alhrhasheh
Emotional Intelligence And Problem-Solving Correlations And Impact On Employability: A Case Study From The Uae, Ganka Ivanova, Rakan Alhrhasheh
All Works
In this study, we aim to address questions about how UAE Leadership Development Plans and Employability connect with current students in UAE classrooms by evaluating the correlation between the employability of UAE university students and their emotional intelligence (EI) and problem-solving skills. Moreover, we cover what must be considered in the curricula of UAE Universities to prepare future leaders to lead the workforce. To that end, we employed an employability test developed by AQR International UK and collected data from 310 undergraduate students aged 17 to 55. Both EI and problem-solving skills were strongly positively correlated with employability (p < .001). Even though male participants scored higher than female participants for EI and problem-solving skills, analysis of variance revealed nonsignificant gender differences (p > .05 …
Eye Of The Beholder: Exploring Correlates Of Subjective Cognition In Older Adults With And Without Insomnia, Amy N. Costa
Eye Of The Beholder: Exploring Correlates Of Subjective Cognition In Older Adults With And Without Insomnia, Amy N. Costa
USF Tampa Graduate Theses and Dissertations
It is unclear how subjective cognition is related to current objective cognitive functioning in older adults, but subjective cognitive complaints are a risk factor for future cognitive decline. A lack of awareness of even subtle changes in objective cognitive performance could lead to missed opportunities for early intervention. Given past work and known associations between sleep, cardiac autonomic functioning, and cognition (both subjective and objective), it is plausible to hypothesize these factors may influence subjective cognition. Understanding how and when the subjective and objective cognition relationship diverges may inform clinicians on how to best assess cognitive functioning and factors (i.e., …
Mutant Kras In Brain Endothelial Cells Promotes Vascular Inflammation And Impairs Vascular Integrity In Brain Arteriovenous Malformation, Jung-Eun Park, Bridger H Freeman, Hyejin Park, Sehee Kim, Adrian E Bafor, Ohnmar Myint, Song Gao, Zhen Xu, Jakob Körbelin, Jaroslaw Aronowski, Peng Roc Chen, Eunhee Kim, Eun S Park
Mutant Kras In Brain Endothelial Cells Promotes Vascular Inflammation And Impairs Vascular Integrity In Brain Arteriovenous Malformation, Jung-Eun Park, Bridger H Freeman, Hyejin Park, Sehee Kim, Adrian E Bafor, Ohnmar Myint, Song Gao, Zhen Xu, Jakob Körbelin, Jaroslaw Aronowski, Peng Roc Chen, Eunhee Kim, Eun S Park
Faculty, Staff and Student Publications
Somatic KRAS (KRASG12V) mutation in endothelial cells (EC) induces brain arteriovenous malformation (bAVM) that could lead to vascular instability and ultimately bleeding. However, the causes of bAVM instability remain unclear. Here we demonstrate that KRASG12V expressing cultured ECs (KRAS-G12V-EC) have increased expression of pro-inflammatory mediators and reduced expression of blood-brain-barrier (BBB) junction constituents. The conditioned medium from KRAS-G12V-EC can activate BV2-microglia (BV2-MG) and conditioned media from this primed BV2-MG can compromise the expression of EC-junction constituents when added to wild-type ECs. In an in vitro BBB model, KRAS-G12V-EC form a dysfunctional EC barrier that is further disrupted, leading to lower …
Sting-Induced Blood-Brain Barrier Opening Combined With Radiotherapy Potentiates Antitumor Response In A High-Grade Glioma Model, Shashwat Tripathi, Hinda Najem, Lisa Hurley, Ruochen Du, Crismita Dmello, Heba Ali, Kathleen Mccortney, Karl J Habashy, Peng Zhang, Craig M Horbinski, Lara Leoni, Ryan J Avery, Rimas V Lukas, Timothy L Sita, David R Raleigh, Sean Sachdev, Roger Stupp, Maciej S Lesniak, David M Ashley, Daniele Procissi, Michael A Curran, Irina Balyasnikova, Amy B Heimberger
Sting-Induced Blood-Brain Barrier Opening Combined With Radiotherapy Potentiates Antitumor Response In A High-Grade Glioma Model, Shashwat Tripathi, Hinda Najem, Lisa Hurley, Ruochen Du, Crismita Dmello, Heba Ali, Kathleen Mccortney, Karl J Habashy, Peng Zhang, Craig M Horbinski, Lara Leoni, Ryan J Avery, Rimas V Lukas, Timothy L Sita, David R Raleigh, Sean Sachdev, Roger Stupp, Maciej S Lesniak, David M Ashley, Daniele Procissi, Michael A Curran, Irina Balyasnikova, Amy B Heimberger
Faculty, Staff and Student Publications
Radiation therapy (RT) is the standard of care for glioblastoma but is not curative. Triggering the cGAS/stimulator of interferon genes (STING) pathway with potent agonists, such as 8803, exerts activity across high-grade glioma preclinical models. To determine if the combination of 8803 with RT warrants consideration in the up-front treatment setting and to clarify the underlying mechanisms of therapeutic activity, C57BL/6J mice harboring intracerebral CT-2A or QPP8v gliomas were treated with RT, intratumoral 8803, or both. The treatment with the combination resulted in 80% long-term survival in the CT-2A model but not in the radiation-resistant QPP8v model. This therapeutic effect …
Addressing Saintly Corrections: An Integrative, Developmental Approach To Counselor Bias Management, Travis Walker, Jennifer M. Cook
Addressing Saintly Corrections: An Integrative, Developmental Approach To Counselor Bias Management, Travis Walker, Jennifer M. Cook
Journal of Counselor Preparation and Supervision
No person is without biases, even the most culturally adept among us. Managing biases is critical to counselors’ continued journey of understanding clients contextually and holistically. In this article, we describe two novel bias management concepts: A specific type of bias called saintly corrections and the more clinically fruitful approach of realistic corrections. We define and illustrate saintly and realistic corrections, outline a multifold approach (i.e., cognitive complexity, cultural identity development, and the multicultural orientation model) for remediating saintly corrections, and offer recommendations counselor educators can use during planned and contextual learning opportunities, including an example of a contextual …
Counselors’ Experiences Of The Alliance In Videoconference Supervision: The Role Of Nonverbals, John E. Trenery, Azra Karajic Siwiec, Randall L. Astramovich
Counselors’ Experiences Of The Alliance In Videoconference Supervision: The Role Of Nonverbals, John E. Trenery, Azra Karajic Siwiec, Randall L. Astramovich
Journal of Counselor Preparation and Supervision
The role of nonverbal immediacy and intimacy in shaping the supervisory alliance during videoconference-based clinical supervision is understudied. Using a generic qualitative research design, data were collected from 15 practicing counselors through semi-structured interviews. Thematic analysis identified six primary themes, highlighting both the perceived barriers and the essential role of nonverbal cues, as well as the need for amplified behaviors in video-based interactions. The findings point to significant gaps in telesupervision training and introduce a novel framework to strengthen telepresence in videoconference supervision. This study offers actionable insight for educational institutions and governing bodies, emphasizing the importance of targeted curricula …
Artificial Intelligence Literacy In Counselor Education: The Developmental Ai Literacy Framework, Leo Gonzalez Jr.
Artificial Intelligence Literacy In Counselor Education: The Developmental Ai Literacy Framework, Leo Gonzalez Jr.
Journal of Counselor Preparation and Supervision
Artificial intelligence (AI) is transforming counselor education, yet frameworks for preparing counselors-in-training (CITs) to use AI remain limited. This article introduces the developmental AI literacy framework (DALF), a conceptual model integrating developmental theory, professional identity formation, and AI literacy. The DALF reframes AI literacy as a developmental competency comprising intentional AI use, critical evaluation, ethical engagement, and awareness of professional identity. The framework outlines three stages, including foundational awareness, reflective application, and integrated professionalization, that parallel CITs’ growth from dependence to autonomy. Pedagogical, developmental, and research implications are provided to guide ethical and reflective AI integration in counselor education.
Stumping The Federal Effort: Southern States’ Contributions To The United States’ Leading Maternal Mortality Rate, Natalie A. Snook
Stumping The Federal Effort: Southern States’ Contributions To The United States’ Leading Maternal Mortality Rate, Natalie A. Snook
Arkansas Law Review
Maternal care has reached a terrifying deficit in the United States. Masses of women throughout this nation are dying preventable deaths resulting from extremely lacking prenatal, birthing, delivery, and postnatal care. This is a silent epidemic. Why is the United States failing so miserably in comparison to its fellow developed countries? Why does the gap appear to be widening more and more each day? Various factors lend themselves to an explanation: general factors like the overall shortage of maternal care providers, as well as specific ones such as the not-so surprising fact that the United States is the only developed …
Ruptured Sinus Of Valsalva Aneurysm In A Patient With Mixed Connective Tissue Disease: Case Report, Kenzo Adhi Wiranata, Pramadya Vardhani Mustafiza, Enrico Ananda Budiono
Ruptured Sinus Of Valsalva Aneurysm In A Patient With Mixed Connective Tissue Disease: Case Report, Kenzo Adhi Wiranata, Pramadya Vardhani Mustafiza, Enrico Ananda Budiono
Journal of the Saudi Heart Association
Sinus of Valsalva aneurysm is a rare cardiac anomaly, affecting approximately 0.09% of the population. Its rupture represents a life-threatening event that can rapidly lead to heart failure. We report a 32-year-old woman with mixed connective tissue disease presenting with right-sided heart failure. Echocardiography demonstrated a ruptured right coronary cusp sinus of valsalva aneurysm into the right ventricle with moderate aortic regurgitation. Surgical repair was successfully performed, and histopathology supported an autoimmune-mediated etiology. To our knowledge, this is the first reported case of ruptured sinus of valsalva aneurysm occurring in a patient with autoimmune mixed connective tissue disease.
Feasibility And Form Factor Validation Of Reflective Shoulder-Mounted Pulse Oximeter In Patients With Suspected Sleep Apnea, Katie N. Kanter, Aaron Wang, David Gordon, Adina Singer, Jacob S. Brenner, Indira Gurubhagavatula, Anush Lingamoorthy, Olumuyiwa Oni, Cameron M. Baston
Feasibility And Form Factor Validation Of Reflective Shoulder-Mounted Pulse Oximeter In Patients With Suspected Sleep Apnea, Katie N. Kanter, Aaron Wang, David Gordon, Adina Singer, Jacob S. Brenner, Indira Gurubhagavatula, Anush Lingamoorthy, Olumuyiwa Oni, Cameron M. Baston
SKMC Student Presentations and Publications
The shoulder may be an effective central site for continuous oxygen saturation (SpO2) monitoring but studies of shoulder-mounted pulse oximetry technology are limited. We hypothesized that an alternative location would be similar in function and user acceptance to a standard FDA-cleared finger-based pulse oximeter. We conducted a quantitative and descriptive pilot study of two prototype biosensor designs in patients with clinical suspicion of hypoxic episodes at an outpatient sleep center. Participants wore two prototype biosensors-the primary a shoulder-mounted adhesive and the secondary a combination ring-bracelet-in addition to a control FDA-approved finger-based pulse oximeter. We assessed the comfort of the devices …
Evaluating Website Resources Shared Online Amongst Women With Intimate Partner Violence Experiences: Analysis Of An Online Health Community, Vivian Hui, Lidan Tian, Malavika Eby, Bohan Zhang, Rose E. Constantino
Evaluating Website Resources Shared Online Amongst Women With Intimate Partner Violence Experiences: Analysis Of An Online Health Community, Vivian Hui, Lidan Tian, Malavika Eby, Bohan Zhang, Rose E. Constantino
SKMC Student Presentations and Publications
INTRODUCTION: Intimate partner violence (IPV) affects around one in four women globally, posing substantial health risks. IPV survivors often consult online health communities for anonymous assistance rather than formal services. Though online health community members frequently share websites to answer questions, no studies have investigated the characteristics and relevance of websites shared in IPV online health communities. This study aims to identify the categories of websites shared in IPV online health communities and evaluate associations between post characteristics and website relevance to survivors' help-seeking needs.
METHODS: Data were extracted from posts and comments on the r/domesticviolence, a subreddit (topic-specific community) …
Hubungan Marketing Mix Dan Hospital Brand Image Dengan Minat Kunjungan Ulang Pasien Di Rsi Sultan Agung Banjarbaru, Fitriani Fitriani, M. Noor Ifansyah, Zubaidah Zubaidah
Hubungan Marketing Mix Dan Hospital Brand Image Dengan Minat Kunjungan Ulang Pasien Di Rsi Sultan Agung Banjarbaru, Fitriani Fitriani, M. Noor Ifansyah, Zubaidah Zubaidah
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
Hospitals are required to provide high-quality services to increase patient visits. Over the past six months, RSI Sultan Agung Banjarbaru has experienced a decline in the number of patient visits. This study aimed to analyze the relationship between the marketing mix and hospital brand image with revisit intention. The study employed a correlational analytic design, involving an outpatient population of 107,146 patients. A total of 100 respondents were selected using purposive sampling, and data were collected through questionnaires. Data analysis was conducted using the Spearman’s Rho test. The results showed that the marketing mix and hospital brand image variables were …
Evolving Strategies In Prostate Cancer: Emerging Approaches And Unmet Needs From The Bridging The Gaps In Prostate Cancer Expert Panel, Rana Mckay, Benjamin Maughan, Alicia Morgans, Neal Shore, Evan Yu, Ravi Madan, Jacob Berchuck, Bradley Carthon, Steven Finkelstein, Leonard Gomella, Michael Gorin, Andrew Hahn, Stacy Loeb, Vivek Narayan, Daniel Petrylak, Charles Ryan, Karine Tawagi, Phuoc Tran, Tanya Dorff
Evolving Strategies In Prostate Cancer: Emerging Approaches And Unmet Needs From The Bridging The Gaps In Prostate Cancer Expert Panel, Rana Mckay, Benjamin Maughan, Alicia Morgans, Neal Shore, Evan Yu, Ravi Madan, Jacob Berchuck, Bradley Carthon, Steven Finkelstein, Leonard Gomella, Michael Gorin, Andrew Hahn, Stacy Loeb, Vivek Narayan, Daniel Petrylak, Charles Ryan, Karine Tawagi, Phuoc Tran, Tanya Dorff
Department of Urology Faculty Papers
BACKGROUND: The expansion of treatment options for prostate cancer (PC) has improved disease-specific and overall survival outcomes but has also raised questions about the optimal level of treatment needed for patients based on their individual prognosis and accounting for potential toxicity, incorporating quality of life considerations.
METHODS: A panel of experts met to discuss current controversies in the care of patients with PC across the disease continuum. Multidisciplinary experts review advances and persistent uncertainties in biomarker-guided assessment, imaging, and systemic therapy for prostate cancer. The discussion outlines priority gaps in evidence that must be addressed to optimize individualized patient care. …
Facebook Interaction As A Potential Marker Of Cognitive Decline: Pilot Study, Esraa M. Qansuwa
Facebook Interaction As A Potential Marker Of Cognitive Decline: Pilot Study, Esraa M. Qansuwa
Theses and Dissertations
One of the critical challenges in brain disorder research is the early identification of individuals with mild cognitive impairment (MCI) who may later develop Alzheimer’s disease (AD) or other dementias. MCI in older adults is frequently associated with diminished social engagement and observable behavioral changes. With the rapid expansion of social media platforms and advances in Machine Learning (ML), digital traces from online activity present a novel and scalable avenue for mental health screening. In particular, predictive ML approaches have demonstrated strong potential in building reliable classifiers for early detection of neurocognitive decline. This study introduces an innovative framework that …
Safety Of Carotid Endarterectomy In The Elderly And Octogenarian Population: A Nationwide Study Including 80,000 Patients, Victor Gabriel El-Hajj, Joanna Roy, Basel Musmar, Wi Jin Kim, Michael Rizzuto, Nathaniel Ellens, Rabab Alshahrani, Victor Staartjes, Adrian Elmi-Terander, Ramachandra Tummala, Stavropoula Tjoumakaris, Michael Gooch, Robert Rosenwasswer, Ziad Khabbaz, Pascal Jabbour
Safety Of Carotid Endarterectomy In The Elderly And Octogenarian Population: A Nationwide Study Including 80,000 Patients, Victor Gabriel El-Hajj, Joanna Roy, Basel Musmar, Wi Jin Kim, Michael Rizzuto, Nathaniel Ellens, Rabab Alshahrani, Victor Staartjes, Adrian Elmi-Terander, Ramachandra Tummala, Stavropoula Tjoumakaris, Michael Gooch, Robert Rosenwasswer, Ziad Khabbaz, Pascal Jabbour
Department of Neurosurgery Faculty Papers
INTRODUCTION: Carotid endarterectomy (CEA) is an established procedure for stroke prevention in patients with carotid artery stenosis. While CEA is considered safe in younger patients, perioperative risks in octogenarians remain debated, with current guidelines classifying the procedure as "high-risk" in this patient population. This study aimed to evaluate short-term outcomes of CEA across age groups and to assess whether comorbidity burden better predicts outcomes than chronological age.
METHODS: The ACS-NSQIP database (2013-2020), was used to identify patients eligible for inclusion. The cohort was stratified based on age < 60, 60-80, and > 80 years. Propensity score matching and multivariable logistic regression were used to compare …
Face And Content Validation Analysis Of The Professional Pain Preparation Questionnaire For Use In Physical Therapist Education, Rodiel Kirby Baloy
Face And Content Validation Analysis Of The Professional Pain Preparation Questionnaire For Use In Physical Therapist Education, Rodiel Kirby Baloy
Journal of Innovation in Health Sciences Education
Introduction: Physical therapy educational preparation for the management of individuals in pain may be determined based on the themes of: (1) level of academic preparation, (2) educational hours spent studying pain, including postgraduate training and certification, and (3) clinical experience. This study assessed the face and content validity of a tool, the Professional Pain Preparation Questionnaire (PPP-Q), to assess expert perception as to the value and relevance of each of the identified domains.
Methods: Twelve respondents were enlisted for face validity, and five experts were recruited for content validity. Descriptive statistics, specifically frequency and percentage, were used to describe …
Penguatan Pengendalian Persediaan Obat Melalui Integrasi Abc-Ven, Eoq, Dan Rop Di Rumah Sakit Rujukan Nasional, Rasendah Rasendah, Helen Andriani, Dendhi Bagus Andriyanto
Penguatan Pengendalian Persediaan Obat Melalui Integrasi Abc-Ven, Eoq, Dan Rop Di Rumah Sakit Rujukan Nasional, Rasendah Rasendah, Helen Andriani, Dendhi Bagus Andriyanto
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
Drug inventory control is a critical component of pharmaceutical management in referral hospitals with high service complexity. This study aimed to evaluate pharmaceutical inventory control performance at the Pharmacy Installation of RSUP Persahabatan and to formulate improvement strategies using an Operational Research approach. A mixed-methods design with a sequential explanatory approach was applied. Quantitative analysis was conducted on 2,291 drug items recorded in the inventory system during October 2025 using ABC-VEN classification to identify priority medicines, followed by calculations of Economic Order Quantity (EOQ) and Reorder Point (ROP). Qualitative data were obtained through in-depth interviews with key informants to strengthen …
Health Science Students’ Knowledge, Attitude, And Readiness Toward Health Management Learning In The Gulf Cooperation Council Region: A Multi-Institutional Study, Ali Artaman, Amjad Abu Elsamen, Hillani Tadesse Bekele, Heba Hijazi, Ghada Moh Samir Elhessewi, Fatima Al-Ghadban, Mohaimen Mansur
Health Science Students’ Knowledge, Attitude, And Readiness Toward Health Management Learning In The Gulf Cooperation Council Region: A Multi-Institutional Study, Ali Artaman, Amjad Abu Elsamen, Hillani Tadesse Bekele, Heba Hijazi, Ghada Moh Samir Elhessewi, Fatima Al-Ghadban, Mohaimen Mansur
All Works
Background: Health management represents a core competency for healthcare professionals, especially in systems experiencing rapid reform and resource constraints. While traditionally overlooked in undergraduate curricula, it is vital for promoting efficiency, patient safety, and interprofessional collaboration. Methods: Four universities were partner sites for this classroom-based research: Zayed University (ZU), with two campuses, the University of Sharjah (US), Princess Noura Bint Abdul Rahman University (PNU), and Kuwait University. A total of 307 health science students were recruited from each university through email and in-class invitations from August 2022 to January 2024. Following the data check, score variables were created for general …
Perceptions Of Ischaemic Heart Disease Risk Among Indian Migrants In Australia: A Qualitative Study, Kunwar Kaur, Ma'en Zaid Abu-Qamar, Amineh Rashidi, Nilufeur Mckay, Rosemary Saunders
Perceptions Of Ischaemic Heart Disease Risk Among Indian Migrants In Australia: A Qualitative Study, Kunwar Kaur, Ma'en Zaid Abu-Qamar, Amineh Rashidi, Nilufeur Mckay, Rosemary Saunders
Research outputs 2022 to 2026
Background: Ischaemic heart disease (IHD) is a global health issue, with people of Indian origin facing earlier onset and more severe cases, leading to higher mortality at younger ages compared to Western countries. Indian migrants maintain similar risks post-migration. Managing modifiable risk factors and improving risk knowledge and health-seeking behaviours are essential, but research on IHD risk perceptions among Indian migrants is limited. Aim: This study explores how first-generation Indian migrants perceive their IHD risk and the factors influencing these perceptions. Methods: As a component of a mixed- method study, a qualitative descriptive study design was employed to examine study …
Mandibular Extension As A Trigger Of The Proprioceptive Trigeminocardiac Reflex, Massimo Conti, Giovanna Traina, Daniele Tonlorenzi
Mandibular Extension As A Trigger Of The Proprioceptive Trigeminocardiac Reflex, Massimo Conti, Giovanna Traina, Daniele Tonlorenzi
Turkish Journal of Medical Sciences
The trigeminocardiac reflex (TCR) is a physiological response characterized by a reduction in heart rate and arterial blood pressure following stimulation of any branch of the fifth cranial nerve. This review presents a novel mechanism of TCR induction through proprioceptive activation of the trigeminal nerve via mandibular extension (ME). Accordingly, it is referred to as the “proprioceptive trigeminocardiac reflex” (pTCR). An overview of the existing literature on ME-evoked TCR in humans and animals is presented, with particular emphasis on evidence of cerebral microcirculatory alterations. The magnitude of cardiovascular responses appears to depend on the duration of ME, with repeated applications …
Heavy Metals As Endocrine Disruptors, Arzu Or Koca
Heavy Metals As Endocrine Disruptors, Arzu Or Koca
Turkish Journal of Medical Sciences
Heavy metals are widely recognized as endocrine-disrupting agents primarily originating from anthropogenic sources and persisting in soil, air, and water. This review aims to present an updated and comprehensive synthesis of current evidence regarding the endocrine-disrupting effects of heavy metals, with particular emphasis on their roles in the pathogenesis of common endocrine and metabolic disorders. The toxicological impact of these elements depends on the level and duration of exposure, their chemical form, and the biological susceptibility of target tissues. Chronic exposure, even at low doses, has been implicated in the development of diabetes mellitus, obesity, autoimmune thyroiditis, thyroid cancer, pubertal …
Canakinumab Treatment In Patients With Colchicine-Resistant Familial Mediterranean Fever: A Multicenter Observational Study, Emrah Koç, Mete Pekdi̇ker, Mete Kara
Canakinumab Treatment In Patients With Colchicine-Resistant Familial Mediterranean Fever: A Multicenter Observational Study, Emrah Koç, Mete Pekdi̇ker, Mete Kara
Turkish Journal of Medical Sciences
Background/aim: Anti-interleukin-1 agents have known beneficial effects in the treatment of colchicine-resistant familial Mediterranean fever (cr-FMF); however, studies to date have tended to have small sample sizes and to be based on pooled data. The present study investigates the efficacy of Canakinumab (CAN) in a homogeneous cohort of cr-FMF cases.
Materials and methods: The study included patients who underwent treatment in three tertiary rheumatology departments, whose electronic medical records were reviewed retrospectively. The inclusion criteria were presence of colchicine resistant disease activity or persistent proteinuria secondary to AA-amyloidosis, and treatment with CAN for at least 6 months. Clinical and laboratory …
Prevalence Of Gout In The Sincan District Of Ankara, Türkiye: A Primary Care-Based Cross-Sectional Study, Riza Can Kardaş, Yasemi̇n Ünsal, Derya Yildirim, Hakan Tüzün, Mustafa Necmi̇ İlhan, Hami̇t Küçük, Abdurrahman Tufan, M. Aki̇f Öztürk
Prevalence Of Gout In The Sincan District Of Ankara, Türkiye: A Primary Care-Based Cross-Sectional Study, Riza Can Kardaş, Yasemi̇n Ünsal, Derya Yildirim, Hakan Tüzün, Mustafa Necmi̇ İlhan, Hami̇t Küçük, Abdurrahman Tufan, M. Aki̇f Öztürk
Turkish Journal of Medical Sciences
Background/aim: Gout, the most prevalent form of inflammatory arthritis, has shown a global increase in prevalence; however, data from Türkiye remain scarce, inconsistent, and largely confined to western regions. This study aimed to estimate the prevalence of gout among adults in the Sincan district of Ankara, Türkiye, and to provide updated data from a previously understudied region.
Materials and methods: This cross-sectional, community-based study employed a multistage design. Adults aged ≥18 years who presented to selected family health centers in Sincan between February and June 2023 were screened using a structured questionnaire. Individuals with suspected gout underwent comprehensive clinical evaluation, …
Evaluation Of The Relationship Between Pan-Immune Inflammation Value And Prognostic Factors In Germ-Cell Testicular Cancer: Analysis Of Stage, Lymph Node Involvement, And Metastasis, Erdi̇nç Di̇nçer, Orkunt Özkaptan, Cengi̇z Çanakçi, Osman Murat İpek, Alper Coşkun, Ahmet Hali̇l Sevi̇nç
Evaluation Of The Relationship Between Pan-Immune Inflammation Value And Prognostic Factors In Germ-Cell Testicular Cancer: Analysis Of Stage, Lymph Node Involvement, And Metastasis, Erdi̇nç Di̇nçer, Orkunt Özkaptan, Cengi̇z Çanakçi, Osman Murat İpek, Alper Coşkun, Ahmet Hali̇l Sevi̇nç
Turkish Journal of Medical Sciences
Background/aim: To evaluate the association between the preoperative pan-immune inflammation value (PIV) and prognostic factors, including stage, lymph node involvement, and metastasis, in patients who underwent radical orchiectomy for germ cell testicular tumors.
Materials and methods: Data from 178 patients who underwent radical orchiectomy for testicular tumors between January 2014 and January 2024 were retrospectively reviewed. Preoperative serum tumor markers, hematologic parameters, and histopathological findings were recorded. Tumor staging was determined based on radiological imaging and serum tumor markers. The PIV was calculated using the formula: (monocyte count × neutrophil count × platelet count) / lymphocyte count. Optimal cut-off values …
Sarcopenia In Atrial Fibrillation: A Prospective Study, Mehmet Aki̇f Topçuoğlu, Ezgi̇ Yilmaz, Di̇nç Doğan Öge, Ali̇ Nai̇m Ceren, Ridvan Muhammed Adin, Ethem Murat Arsava
Sarcopenia In Atrial Fibrillation: A Prospective Study, Mehmet Aki̇f Topçuoğlu, Ezgi̇ Yilmaz, Di̇nç Doğan Öge, Ali̇ Nai̇m Ceren, Ridvan Muhammed Adin, Ethem Murat Arsava
Turkish Journal of Medical Sciences
Background/aim: The link between atrial fibrillation (AF) and lean body mass is unclear. This study presents the effects of AF on sarcopenia indices, including ultrasonographic muscle architecture.
Materials and methods: In this study conducted in neurology units, 72 subjects with AF (mean age: 71 ± 11years, 49% female) were compared with 538 without AF (mean age:66±12years; 53% female) in terms of sarcopenia indices [anthropometry; Short Physical Performance Battery (SPPB); hand grip strength (HGS); bioimpedance analysis (BIA) indices; skeletal muscle mass index (SMMI) normalized to weight, height and body mass index (BMI); and phase angle (PhA)]; muscle ultrasonography [thickness, cross-section area …
Validity Of The Turkish Version Of The Oral Frailty Index-8 And Its Relationship With Frailty, Malnutrition, And Sarcopenia In Older Adults, Süleyman Emre Koçyi̇ği̇t, Bi̇lal Kati̇poğlu, Yilmaz Önal, Kübra Bahar Baykan, İlknur Şeker Kaya, Fatma Sena Dost, Özge Dokuzlar, Esra Ateş Bulut, Ali̇ Ekrem Aydin, Derya Kaya, Ahmet Turan Işik
Validity Of The Turkish Version Of The Oral Frailty Index-8 And Its Relationship With Frailty, Malnutrition, And Sarcopenia In Older Adults, Süleyman Emre Koçyi̇ği̇t, Bi̇lal Kati̇poğlu, Yilmaz Önal, Kübra Bahar Baykan, İlknur Şeker Kaya, Fatma Sena Dost, Özge Dokuzlar, Esra Ateş Bulut, Ali̇ Ekrem Aydin, Derya Kaya, Ahmet Turan Işik
Turkish Journal of Medical Sciences
Background/aim: The Oral Frailty Index-8 (OFI-8) is a reliable screening for oral frailty. In our study, while presenting the Turkish reliability and validity study of the OFI-8, we also aimed to establish a cut-off value for oral frailty in Turkish population.
Materials and methods: Patients who presented to the outpatient clinic between January 2024 and January 2025 were evaluated. The test’s internal consistency and test–retest reliability were assessed. Divergent validity was evaluated using frailty scores, muscle strength, and nutritional status. A receiver operating characteristic (ROC) curve was generated to determine the optimal cut-off values for identifying frailty, malnutrition, and probable …
Preference Of Mechanical Ventilation Modes Among Intensivists In Türkiye: A National Wide, Point Prevalence Study, Süleyman Yildirim, Nurhayat Kilinç Özgün, Özcan Alpdoğan, Hüseyi̇n Uçar, İmren Taşkiran, Adnan Ata, Özhan Özcan, Kivanç Öncü, Saba Mukaddes Acarbay, Temel Güner, Pinar Özgün, Zerri̇n Özçeli̇k, Ayşegül Çinaroğlu, Gi̇zem Kurada, L. Serap Avlaği, Onur Gökçe, Özkul Yilmaz Çolak, Fatma Ülger, Melda İşevi̇, Özgür Kiliç, Rahi̇me Aydin Kayali, Meti̇n Yarici, Berkay Küçük, Fatma Yildirim, Kami̇l Gönderen, Bi̇şar Ergün, Kutlay Aydin, Kamuran Uluç, Sevda Onuk, Mi̇ne Altinkaya Çavuş, Yelda Balik, Ahmet Sari, Hayri̇ye Cankar Dal, Şeri̇fe Gökbulut Bektaş, Sema Turan, Ferhan Demi̇rer Aydemi̇r, Türkay Akbaş, Hamza Gülteki̇n, Kani̇ye Aydin, Seli̇n Eyüpoğlu, Havva Kocayi̇ği̇t, Gürhan Taşkin, Kazim Rollas, Mensure Çakirgöz, Cenk Kirakli
Preference Of Mechanical Ventilation Modes Among Intensivists In Türkiye: A National Wide, Point Prevalence Study, Süleyman Yildirim, Nurhayat Kilinç Özgün, Özcan Alpdoğan, Hüseyi̇n Uçar, İmren Taşkiran, Adnan Ata, Özhan Özcan, Kivanç Öncü, Saba Mukaddes Acarbay, Temel Güner, Pinar Özgün, Zerri̇n Özçeli̇k, Ayşegül Çinaroğlu, Gi̇zem Kurada, L. Serap Avlaği, Onur Gökçe, Özkul Yilmaz Çolak, Fatma Ülger, Melda İşevi̇, Özgür Kiliç, Rahi̇me Aydin Kayali, Meti̇n Yarici, Berkay Küçük, Fatma Yildirim, Kami̇l Gönderen, Bi̇şar Ergün, Kutlay Aydin, Kamuran Uluç, Sevda Onuk, Mi̇ne Altinkaya Çavuş, Yelda Balik, Ahmet Sari, Hayri̇ye Cankar Dal, Şeri̇fe Gökbulut Bektaş, Sema Turan, Ferhan Demi̇rer Aydemi̇r, Türkay Akbaş, Hamza Gülteki̇n, Kani̇ye Aydin, Seli̇n Eyüpoğlu, Havva Kocayi̇ği̇t, Gürhan Taşkin, Kazim Rollas, Mensure Çakirgöz, Cenk Kirakli
Turkish Journal of Medical Sciences
Background/aim: Invasive mechanical ventilation (IMV) is a fundamental intervention for patients with respiratory failure in intensive care units (ICUs). This nationwide, multicenter point-prevalence study aimed to describe current mechanical ventilation mode preferences (conventional, adaptive, and biphasic) in Turkish ICUs and to report associated clinical outcomes descriptively, without assessing causal relationships.
Materials and methods: A nationwide, multicenter point-prevalence study was conducted on 17 April 2024 and included adult patients (≥18 years) who had been receiving IMV for more than 24 h. Data on patient demographics, ventilation mode distribution, ventilatory parameters, and descriptive clinical outcomes on day 28 (weaning status, tracheostomy, and …