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Articles 2431 - 2460 of 23291
Full-Text Articles in Entire DC Network
The Relationship Of Online Learning And Information Technology With Cognitive, Affective, And Psychomotor Abilities, Sidik Awaludin, Usman Chatib Warsa, Soetrisno Soemardjo, Elly Nurachmah, Arum Atmawikarta, Dwi Novitasari
The Relationship Of Online Learning And Information Technology With Cognitive, Affective, And Psychomotor Abilities, Sidik Awaludin, Usman Chatib Warsa, Soetrisno Soemardjo, Elly Nurachmah, Arum Atmawikarta, Dwi Novitasari
Jurnal Keperawatan Indonesia
The COVID-19 pandemic had a significant impact on education in nursing programs. Changes in the learning system were followed by changes in learning methods and information technology as a means of support. In fact, mastery of learning methods and information technology support is still not optimal. To improve students’ cognitive, affective, and psychomotor capacities, lecturers must grasp numerous learning approaches and information technology. This study aimed to examine the relationship of mastery of online learning methods and information technology assistance with nursing students’ cognitive, emotional, and psychomotor capacities in Indonesia. The design of this study was a cross- sectional internet-based …
Development Of A New Peyronie’S Disease Self-Assessment Screening App, Gregory A Broderick, Jesse N Mills, Lisa Bathish, Christopher Davis, Mohit Khera
Development Of A New Peyronie’S Disease Self-Assessment Screening App, Gregory A Broderick, Jesse N Mills, Lisa Bathish, Christopher Davis, Mohit Khera
Faculty, Staff and Students Publications
Peyronie's disease (PD) is an underdiagnosed and undertreated fibroproliferative disorder associated with the formation of plaques that results in penile curvature and discourages some men from seeking medical consultation. The PD self-assessment app, a digital application (app), was developed to increase PD awareness, provide men with a self-screening and educational tool for PD, and help eliminate barriers to seeking consultation with a physician. Prior to deployment, 4 board-certified urologists provided qualitative reviews on the app's usability and utility as a screening tool. The PD self-assessment app features a questionnaire that addresses penile curvature, challenges with penetration, partner distress, and the …
Early Detection Of Risk Factor For Suicidal Ideation Among Senior High School Students In Jakarta: Updated Measurement, Nova R. Yusuf, Sabarinah Prasetyo, Byron J. Good
Early Detection Of Risk Factor For Suicidal Ideation Among Senior High School Students In Jakarta: Updated Measurement, Nova R. Yusuf, Sabarinah Prasetyo, Byron J. Good
Kesmas
The key strategy to address suicide in adolescents is school-based suicidal prevention by adapting a screening instrument to the local culture and policymakers’ perception of suicide. This study aimed to develop an instrument for the early detection of risk for suicidal ideation and identify influential risk factors for suicidal ideation among high school students in Jakarta, Indonesia. This study was conducted in 2018 with a mixed-method design (quantitative and qualitative approaches). It was found that 5% of students had suicidal ideation in July–November 2018, and 13.8% had a high-risk factor for suicidal ideation. The instrument developed in this study consisted …
Assessment Of Free Drinking Water Facilities And Its Potential Health Risks: A Study In The University X, Indah Actry Zane Lumbantobing, Bambang Wispriyono, Fitri Kurniasari, Sifa Fauzia, Muhammad Nur Ihsan Ayyasy, Alissa Siti Haura, Ghina Labibah, Muhammad Abiyyu Akmal, Kirana Mahadewi Heryadi, Firda Alfianti, Nuranida Fauziyah
Assessment Of Free Drinking Water Facilities And Its Potential Health Risks: A Study In The University X, Indah Actry Zane Lumbantobing, Bambang Wispriyono, Fitri Kurniasari, Sifa Fauzia, Muhammad Nur Ihsan Ayyasy, Alissa Siti Haura, Ghina Labibah, Muhammad Abiyyu Akmal, Kirana Mahadewi Heryadi, Firda Alfianti, Nuranida Fauziyah
Kesmas
University X offers free drinking water facilities. However, it has a significant problem in accessing safe drinking water. This study aimed to examine the microbial and chemical parameters of the free drinking water facilities at University X. The microbial quality was assessed by evaluating the total coliform bacteria, and the chemical parameter assessment, substances such as nitrate, iron, manganese, hexavalent chromium, and fluoride were analyzed across 12 water samples from various locations within the university. Among these, only total coliform and fluoride levels exceeded the guidelines of the World Health Organization (WHO) and the Indonesian Ministry of Health. An Environmental …
Telemedicine Adoption In Developing Economies: A Systematic Review On The Enablers And Barriers, Zaidbren Macabato, Lemuel Clark Velasco, Art Brian Escabarte, Mae-Lanie Ong Poblete, Armando Isla Jr., Rentor Cafino, Sarah Lizette Aquino-Cafino, Frevy Teofilo-Orencia
Telemedicine Adoption In Developing Economies: A Systematic Review On The Enablers And Barriers, Zaidbren Macabato, Lemuel Clark Velasco, Art Brian Escabarte, Mae-Lanie Ong Poblete, Armando Isla Jr., Rentor Cafino, Sarah Lizette Aquino-Cafino, Frevy Teofilo-Orencia
Kesmas
Telemedicine’s adoption has been effective in certain contexts despite being controversial in certain settings because of its tendency to cause misdiagnosis and concerns about data privacy. This study aimed to synthesize the research findings on the factors leading to the adoption of telemedicine among developing economies. The study utilized Preferred Reporting Items for Systematic Reviews and Meta-Analysis methodology to analyze 27 related literature and the Unified Theory of Acceptance and Use of Technology to map out the factors considered enablers and barriers in adopting telemedicine. Results showed that performance expectancy, effort expectancy, social influence, and facilitating conditions were significant predictors. …
De-Identification Is Not Enough: A Comparison Between De-Identified And Synthetic Clinical Notes, Atiquer Rahman Sarkar, Yao-Shun Chuang, Noman Mohammed, Xiaoqian Jiang
De-Identification Is Not Enough: A Comparison Between De-Identified And Synthetic Clinical Notes, Atiquer Rahman Sarkar, Yao-Shun Chuang, Noman Mohammed, Xiaoqian Jiang
Faculty, Staff and Student Publications
For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data generative models and the breakthroughs in large generative language models raise the question of whether synthetically generated clinical notes could be a viable alternative to real notes for research purposes. In this work, we demonstrated that (i) de-identification of real clinical notes does not protect records against a membership inference attack, (ii) proposed a novel approach to generate synthetic clinical notes using the current state-of-the-art large language models, (iii) evaluated …
Spatial Pattern And Differential Expression Analysis With Spatial Transcriptomic Data, Fei Qin, Xizhi Luo, Bo Cai Ph.D., Feifei Xiao, Guoshuai Cai
Spatial Pattern And Differential Expression Analysis With Spatial Transcriptomic Data, Fei Qin, Xizhi Luo, Bo Cai Ph.D., Feifei Xiao, Guoshuai Cai
Faculty Publications
The emergence of spatial transcriptomic technologies has opened new avenues for investigating gene activities while preserving the spatial context of tissues. Utilizing data generated by such technologies, the identification of spatially variable (SV) genes is an essential step in exploring tissue landscapes and biological processes. Particularly in typical experimental designs, such as case-control or longitudinal studies, identifying SV genes between groups is crucial for discovering significant biomarkers or developing targeted therapies for diseases. However, current methods available for analyzing spatial transcriptomic data are still in their infancy, and none of the existing methods are capable of identifying SV genes between …
Pediatric Renal Cell Carcinoma (Prcc) Subpopulation Environmental Differentials In Survival Disadvantage Of Black/African American Children In The United States: Large-Cohort Evidence, Laurens Holmes, Phatismo Masire, Arieanna Eaton, Robert Mason, Mackenzie Holmes, Justin William, Maura Poleon, Michael Enwere
Pediatric Renal Cell Carcinoma (Prcc) Subpopulation Environmental Differentials In Survival Disadvantage Of Black/African American Children In The United States: Large-Cohort Evidence, Laurens Holmes, Phatismo Masire, Arieanna Eaton, Robert Mason, Mackenzie Holmes, Justin William, Maura Poleon, Michael Enwere
College of Population Health Faculty Papers
OBJECTIVE: Renal cell carcinoma (RCC) is a rare but severe and aggressive pediatric malignancy. While incidence is uncommon, survival is relatively low with respect to acute lymphocytic leukemia (ALL), AML, lymphoma, ependymoma, glioblastoma, and Wilms Tumor. The pediatric renal cell carcinoma (pRCC) incidence, cumulative incidence (period prevalence), and mortality vary by health disparities' indicators, namely sex, race, ethnicity, age at tumor diagnosis, and social determinants of health (SDHs) as well as Epigenomic Determinants of Health (EDHs). However, studies are unavailable on some pRCC risk determinants, such as area of residence and socio-economic status (SES). The current study aimed at assessing …
Association Between Various Types Of Corticosteroids And Mortality For Severe Community-Acquired Pneumonia In Adults: A Systematic Review And Network Meta-Analysis, Peng Wang, Jun Wan, Qiaoyu You, Yuxin Zheng, Wenhao Xu, Jialing He, Liyuan Peng, Cuyubamba Dominguez Jorge Luis, Yuning Feng, Ping Xu, Xinrong Li, Weelic Chong, Yang Hai, Lu Jia, Fang Fang, Yu Zhang
Association Between Various Types Of Corticosteroids And Mortality For Severe Community-Acquired Pneumonia In Adults: A Systematic Review And Network Meta-Analysis, Peng Wang, Jun Wan, Qiaoyu You, Yuxin Zheng, Wenhao Xu, Jialing He, Liyuan Peng, Cuyubamba Dominguez Jorge Luis, Yuning Feng, Ping Xu, Xinrong Li, Weelic Chong, Yang Hai, Lu Jia, Fang Fang, Yu Zhang
Department of Medical Oncology Faculty Papers
OBJECTIVE: This study aims to conduct a systematic review and network meta-analysis to evaluate the efficacy and safety of specific corticosteroids, including but not limited to hydrocortisone, methylprednisolone, prednisolone, and dexamethasone, in the treatment of severe community-acquired pneumonia (SCAP). Efficacy will be assessed using specific outcomes, such as 30-day mortality and the requirement for mechanical ventilation. Safety evaluations will include adverse events like gastrointestinal bleeding and healthcare-associated infections. The study seeks to address the gaps identified in the latest guidelines regarding the optimal use of different corticosteroid types and to provide recommendations for clinical practice.
DATA SOURCES: This study conducted …
3d Reconstruction And Comparative Anatomical And Kinematic Analyses Of The Foot Of Archaeopteryx, Alexander M. Kirk
3d Reconstruction And Comparative Anatomical And Kinematic Analyses Of The Foot Of Archaeopteryx, Alexander M. Kirk
USF Tampa Graduate Theses and Dissertations
Research on the evolution of dinosaur flight has long been dominated by the wing, often overlooking the foot. The foot of Archaeopteryx, the “icon of evolution”, thus offers a unique opportunity to investigate this critical evolutionary stage. Chapter I of this dissertation integrates advanced 3D reconstruction techniques, combining photogrammetry with X-ray data, to create a high-resolution model of the foot of the Thermopolis specimen of Archaeopteryx for visualization and analysis. Driven by 3D coordinate axes derived from joint surface topology, the analyses in Chapter II reveal terrestrial adaptations -- such as a medially oriented hallux (81°), serially shorter phalanges on …
Cabotegravir Maintains Protective Efficacy In The Setting Of Bacterial Stis: A Secondary Analysis Of Hptn 083, Meredith E. Clement, Brett Hanscom, Daniel Haines, Jose A. Bazan, Nuntisa Chotirosniramit, Ryan Kofron, Sharon Mannheimer, Kenneth H. Mayer, Mayara Secco Torres Silva, Lydia Soto-Torres, Alex R. Rinehart, James F. Rooney, A Jennings, K Gomez-Feliciano, Marybeth Mccauley, Beatriz Grinsztejn, Raphael J. Landovitz, Et Al.
Cabotegravir Maintains Protective Efficacy In The Setting Of Bacterial Stis: A Secondary Analysis Of Hptn 083, Meredith E. Clement, Brett Hanscom, Daniel Haines, Jose A. Bazan, Nuntisa Chotirosniramit, Ryan Kofron, Sharon Mannheimer, Kenneth H. Mayer, Mayara Secco Torres Silva, Lydia Soto-Torres, Alex R. Rinehart, James F. Rooney, A Jennings, K Gomez-Feliciano, Marybeth Mccauley, Beatriz Grinsztejn, Raphael J. Landovitz, Et Al.
School of Medicine Faculty Publications
BACKGROUND: Sexually transmitted infections (STIs) have been shown to facilitate HIV transmission and acquisition. HPTN 083, a global clinical trial, demonstrated superiority of long-acting cabotegravir (CAB-LA) versus daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for HIV prevention among transgender women and cisgender men who have sex with men. This analysis assessed whether CAB-LA maintained protective efficacy when bacterial STIs (syphilis, rectal/urethral gonorrhea and chlamydia) were present. METHODS: STI events per 100 person-years (PY) were calculated, including by subgroups (age, race/ethnicity, gender, education, treatment arm, drug use, alcohol use, region/country, condom usage, partner number, marital status, baseline STI). Association between baseline factors …
Evaluating How Malaria Transmission Season, Residency, And Travel History Modify The Association Between Vector Control Method Use And P. Falciparum Infection In Accra, Ghana., Anna Beltrame
USF Tampa Graduate Theses and Dissertations
Background. Urbanization and population movements increase urban malaria risk, necessitating adjustments to traditional control strategies. Data on vector control methods in urban African settings and their association with malaria risk remain limited.
Objectives. To evaluate the association between vector control methods and Plasmodium falciparum infection in Accra, Ghana, and how this association varies by malaria transmission season, residency, and travel history.
Methods. This observation study utilized data from two cross-sectional household surveys conducted in March-April and June-July 2024 as part of the MUSE study. Participants were household members over six months old who gave consent, randomly selected from 13 health …
Evaluating Trauma-Informed Design In A Mental Health Setting: A Community-Based Research Case Study, Marie Spence
Evaluating Trauma-Informed Design In A Mental Health Setting: A Community-Based Research Case Study, Marie Spence
Electronic Theses and Dissertations
This case study utilized a community-based research framework to explore how the Trauma-Informed Design framework can be implemented in a mental health setting. This study focused on the site of Empower Therapy Practice, a private mental health practice in the Denver Metro Area, to engage clients and staff to participate in advisory boards and inform the interior design of a new office space. To explore the application of Trauma-Informed Design, participants engaged in a variety of research activities, including an evaluative questionnaire, Photovoice, and focus group. Advisory board members identified various aspects of Trauma-Informed Design which meaningfully translate to therapeutic …
The Impact Of Cumulative And Acute Loading On Achilles Tendon Health, Performance, And Reported Pain In Collegiate Gymnasts, Julio Serrano Samayoa
The Impact Of Cumulative And Acute Loading On Achilles Tendon Health, Performance, And Reported Pain In Collegiate Gymnasts, Julio Serrano Samayoa
Electronic Theses and Dissertations
Gymnasts are at a high risk of Achilles tendon (AT) injuries due to intense loads during takeoffs and landings. To better understand better the relationship between impact loading and its effects on tendon adaptation and athletic performance, this study uses Inertial Measurement Units (IMUs) to track AT loading across a collegiate gymnastics season. This data were compared against physiological and athletic performance metrics, obtained through force plates and ultrasound imaging, to explore how mechanical load influences reported pain and athletic performance. Results varied, with cumulative impacts being correlated with improved jump height (Spearman 0.362, Pearson 0.348), while peak power and …
Hurricane Evacuation: Navigating Uncertainty During Covid 19 And With Existing Communication Scales, And Considering Public And Expert Perception Of Alternative Scales, Leilani D. Paxton
Hurricane Evacuation: Navigating Uncertainty During Covid 19 And With Existing Communication Scales, And Considering Public And Expert Perception Of Alternative Scales, Leilani D. Paxton
USF Tampa Graduate Theses and Dissertations
This dissertation investigates the effectiveness of current hurricane warning products and communication strategies, exploring factors influencing public perception of risk and decision-making during evacuations. The study employs a mixed-methods approach, combining survey data, focus group discussions, and interviews with meteorologists and emergency managers. The first paper examines the impact of the COVID-19 pandemic on hurricane risk perception and evacuation decisions. Findings indicate that while COVID-19 concerns played a role in some individuals' decisions, particularly those with pets or concerns about shelter conditions, the majority of participants evacuated for Hurricane Ian. The study highlights the importance of providing clear, consistent, and …
Lengthening Atlantic Hurricane Seasons With Earlier Storm Formation Dates Including Implications From 2020, Barry D. Keim, L. C. Hamilton, V. M. Brown, P. J. Klotzbach, A. B. Lewis, D. T. Thompson
Lengthening Atlantic Hurricane Seasons With Earlier Storm Formation Dates Including Implications From 2020, Barry D. Keim, L. C. Hamilton, V. M. Brown, P. J. Klotzbach, A. B. Lewis, D. T. Thompson
School of Public Health Faculty Publications
This paper analyzes the formation dates of the nth storm in a sequence for all named North Atlantic tropical cyclones (TCs) and assesses whether the intraseasonal length of the Atlantic hurricane season has changed temporally. The record-breaking 2020 season, with 30 named storms, set records for the earliest third TC formation (Cristobal) and from the sixth TC (Fay) onward. Analysis of season length from 1851 to 2022 identifies only one statistically significant breakpoint detected in the early 1970s, roughly coinciding with the introduction of satellite observations. Since 1970, we also find a trend toward longer North Atlantic hurricane seasons. The …
Smartphone Haptics Can Uncover Differences In Touch Interactions Between Asd And Neurotypicals, Ivonne Monarca, Franceli L. Cibrian, Isabel López Hurtado, Monica Tentori
Smartphone Haptics Can Uncover Differences In Touch Interactions Between Asd And Neurotypicals, Ivonne Monarca, Franceli L. Cibrian, Isabel López Hurtado, Monica Tentori
Engineering Faculty Articles and Research
Utilizing touch interactions from smartphones for gathering data and identifying digital markers for screening and monitoring neurological disorders, such as Autism Spectrum Disorder (ASD), is an emerging area of research. Smartphones provide multiple benefits for this kind of study, including unobtrusive data collection via built-in sensors, integrated haptic feedback systems, and the capability to create specialized applications. Acknowledging the significant yet understudied presence of tactile processing differences in individuals with ASD, we designed and developed Feel and Touch, a mobile game that leverages the haptic capabilities of smartphones. This game provides vibrotactile feedback in response to touch interactions and collects …
Moving From Traits To The Dynamic Process: The Next Steps In Research On Human Resilience, Yannick Hill, Michael L. Dolezal, Patric C. Nordbeck, Ruud J. R. Den Hartigh, David Pincus, Adam W. Kiefer, Bernard P. Ricca
Moving From Traits To The Dynamic Process: The Next Steps In Research On Human Resilience, Yannick Hill, Michael L. Dolezal, Patric C. Nordbeck, Ruud J. R. Den Hartigh, David Pincus, Adam W. Kiefer, Bernard P. Ricca
Psychology Faculty Articles and Research
The current literature on resilience shows a trend toward a dynamic process conceptualization, moving away from the previous trait-approach. However, the term “dynamic” is increasingly treated as a buzzword and is thereby oversimplified in the literature. The aim of this article is to develop a unified language pertaining to resilience as a dynamic process, so as to ensure progress in this field. First, we briefly introduce the traditional trait approach alongside the implicit assumption on which it is built. Next, we contrast this approach by discussing what dynamics entail and how this approach differs from mainstream psychological approaches. Specifically, dynamics …
Mediator Kinase Inhibitors Suppress Triple-Negative Breast Cancer Growth And Extend Tumor Suppression By Mtor And Akt Inhibitors, Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor Roninson, Eugenia Broude
Mediator Kinase Inhibitors Suppress Triple-Negative Breast Cancer Growth And Extend Tumor Suppression By Mtor And Akt Inhibitors, Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor Roninson, Eugenia Broude
Faculty Publications
Triple-negative breast cancers (TNBC) are treated primarily by chemotherapy and lack clinically validated therapeutic targets. In particular, inhibitors of the PI3K/AKT/mTOR pathway, abnormally activated in many breast cancers, failed to achieve clinical efficacy in TNBC due to the development of adaptive drug resistance, which is largely driven by the transcriptomic plasticity of TNBC. Expression of CDK8/19 Mediator kinases that control transcriptional reprogramming correlates with relapse-free survival and treatment failure in breast cancer patients, including TNBC. We now investigated how CDK8/19 inhibitors affect the growth of TNBC tumors and their response to mTOR and AKT inhibitors. In contrast to the effects …
Disparities In The Prevalence Of Hospitalizations And In-Hospital Mortality Due To Acute Myocardial Infarction Among Patients With Non-Alcoholic Fatty Liver Disease: A Nationwide Retrospective Study, Umar Hayat, Faisal Kamal, Muhammad Kamal, Wasique Mirza, Tariq Ahmad, Manesh Gangwani, Dushyant Dahiya, Hassam Ali, Shiva Naidoo, Sara Humayun, Hayrettin Okut, Muhammad Aziz
Disparities In The Prevalence Of Hospitalizations And In-Hospital Mortality Due To Acute Myocardial Infarction Among Patients With Non-Alcoholic Fatty Liver Disease: A Nationwide Retrospective Study, Umar Hayat, Faisal Kamal, Muhammad Kamal, Wasique Mirza, Tariq Ahmad, Manesh Gangwani, Dushyant Dahiya, Hassam Ali, Shiva Naidoo, Sara Humayun, Hayrettin Okut, Muhammad Aziz
Division of Gastroenterology and Hepatology Faculty Papers
Background: Non-alcoholic liver disease (NAFLD) may be associated with cardiovascular diseases; however, only a few studies have analyzed this relationship. We aimed to assess the epidemiologic data and the association between NAFLD and acute myocardial infarction (AMI) in the United States. Methods: The National Inpatient Sample (NIS) database 2016-2019 was queried using ICD10-CM diagnostic codes to identify hospitalizations of AMI + NAFLD. Essential demographic variables were analyzed to determine the disparities in the prevalence of AMI hospitalizations and deaths among NAFLD patients. Univariate and multivariate logistic regression models determined the association between NAFLD and AMI hospitalizations and death. …
11.18.2024 Orsp Connect, Liz Williamson
11.18.2024 Orsp Connect, Liz Williamson
ORED Newsletter
Director of Research Lab Safety
GIS Day
Tech Startup Weekend
NSF Virtual Grants Conference
Is Warmer Better? Examining Counseling Student Responses To Syllabus Tone, Angela I. Sheely-Moore, Leeann Cardaciotto, Krista Malott, Megan Krell, Carlos A. Flores
Is Warmer Better? Examining Counseling Student Responses To Syllabus Tone, Angela I. Sheely-Moore, Leeann Cardaciotto, Krista Malott, Megan Krell, Carlos A. Flores
Journal of Counselor Preparation and Supervision
Researchers in this quantitative study explored the impact of syllabus tone on master-level counseling students (N = 124). Findings indicate statistically significant differences between students’ reactions to syllabi language, with greater student retention of the content within the warm syllabus condition and more favorable perceptions of the instructor and their grading practices. Implications for counselor educators are included.
The Santa Clara, 2024-11-15, Santa Clara University
The Santa Clara, 2024-11-15, Santa Clara University
The Santa Clara
No abstract provided.
Lung Tissue Multilayer Network Analysis Uncovers The Molecular Heterogeneity Of Chronic Obstructive Pulmonary Disease, Nuria Olvera, Jon Sánchez-Valle, Iker Núñez-Carpintero, Joselyn Rojas-Quintero, Guillaume Noell, Sandra Casas-Recasens, Alen Faiz, Philip Hansbro, Angela Guirao, Rosalba Lepore, Davide Cirillo, Alvar Agustí, Francesca Polverino, Alfonso Valencia, Rosa Faner
Lung Tissue Multilayer Network Analysis Uncovers The Molecular Heterogeneity Of Chronic Obstructive Pulmonary Disease, Nuria Olvera, Jon Sánchez-Valle, Iker Núñez-Carpintero, Joselyn Rojas-Quintero, Guillaume Noell, Sandra Casas-Recasens, Alen Faiz, Philip Hansbro, Angela Guirao, Rosalba Lepore, Davide Cirillo, Alvar Agustí, Francesca Polverino, Alfonso Valencia, Rosa Faner
Faculty, Staff and Students Publications
Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition. Objectives: We hypothesized that the unbiased integration of different COPD lung omics using a novel multilayer approach might unravel mechanisms associated with clinical characteristics.
Methods: We profiled mRNA, microRNA and methylome in lung tissue samples from 135 former smokers with COPD. For each omic (layer), we built a patient network on the basis of molecular similarity. The three networks were used to build a multilayer network, and optimization of multiplex modularity was used to identify patient communities across the three distinct layers. Uncovered communities were related to clinical features.
Measurements …
Mitochondrial Pyruvate Transport Regulates Presynaptic Metabolism And Neurotransmission, Anupama Tiwari, Jongyun Myeong, Arsalan Hashemiaghdam, Marion I Stunault, Hao Zhang, Xiangfeng Niu, Marissa A Laramie, Jasmin Sponagel, Leah P Shriver, Gary J Patti, Vitaly A Klyachko, Ghazaleh Ashrafi
Mitochondrial Pyruvate Transport Regulates Presynaptic Metabolism And Neurotransmission, Anupama Tiwari, Jongyun Myeong, Arsalan Hashemiaghdam, Marion I Stunault, Hao Zhang, Xiangfeng Niu, Marissa A Laramie, Jasmin Sponagel, Leah P Shriver, Gary J Patti, Vitaly A Klyachko, Ghazaleh Ashrafi
2020-Current year OA Pubs
Glucose has long been considered the primary fuel source for the brain. However, glucose levels fluctuate in the brain during sleep or circuit activity, posing major metabolic stress. Here, we demonstrate that the mammalian brain uses pyruvate as a fuel source, and pyruvate can support neuronal viability in the absence of glucose. Nerve terminals are sites of metabolic vulnerability, and we show that mitochondrial pyruvate uptake is a critical step in oxidative ATP production in hippocampal terminals. We find that the mitochondrial pyruvate carrier is post-translationally modified by lysine acetylation, which, in turn, modulates mitochondrial pyruvate uptake. Our data reveal …
Alabama Agricultural Producers’ Experiences With Wild Pigs (Sus Scrofa) And Their Preferences Concerning Wild Pig Management, Hailey E. Ellis, Luren M. Jaebker, Alan D. Bright, Mark D. Smith, Keith M. Carlisle
Alabama Agricultural Producers’ Experiences With Wild Pigs (Sus Scrofa) And Their Preferences Concerning Wild Pig Management, Hailey E. Ellis, Luren M. Jaebker, Alan D. Bright, Mark D. Smith, Keith M. Carlisle
United States Department of Agriculture Wildlife Services: Staff Publications
Government agencies and landowners use a variety of lethal methods to reduce invasive wild pig populations and resulting agricultural damages. To provide decision-makers with information regarding Alabama farmers’ experiences with wild pigs and their preferences for management actions, we surveyed Alabama Farmers Federation members in 2020. We found that wild pigs were commonly present on livestock, timber, and crop production acreage, but wild pig damages and costs were much more common among crop producers. Respondents' wildlife acceptance capacity for wild pigs was low and all lethal control methods were considered aceptable by most reposndents, particularly those performed by landowners. While …
Experiences Of Using Electronic Medical Records Among Patients From Ethnic Minority Backgrounds: A Rapid Review, Corey Adams, Reema Harrison, Alison Merchant, Narelle Arblaster, Tracey Bucknall, Kathleen Gray, Guncag Ozavci, Nilmini Wickramasinghe, Vicky Yuan, Elizabeth Manias
Experiences Of Using Electronic Medical Records Among Patients From Ethnic Minority Backgrounds: A Rapid Review, Corey Adams, Reema Harrison, Alison Merchant, Narelle Arblaster, Tracey Bucknall, Kathleen Gray, Guncag Ozavci, Nilmini Wickramasinghe, Vicky Yuan, Elizabeth Manias
Patient Experience Journal
This study explores the experiences of individuals from ethnic minority backgrounds using electronic medical records (EMRs) and identifies strategies to improve the inclusivity and usability of EMRs, aiming to reduce the digital divide in their access and use. A rapid review of the literature was conducted using Medline, Embase, and CINAHL databases to identify relevant studies published between 2010 and November 2023, with the assistance of a medical librarian.
A total of 44 studies were included in the review, revealing significant disparities in EMR adoption and utilization among ethnic minority groups. Three key themes of inequality were identified: presentation of …
Driving Healthy Behaviors Through Social Support: The Role Of Co-Responsibility In Weight Loss And Maintenance, Melanie Knufinke-Meyfroyt, Carlo Lancia, Yentl Lodewijks, Simon Nienhuijs, Eva Deckers
Driving Healthy Behaviors Through Social Support: The Role Of Co-Responsibility In Weight Loss And Maintenance, Melanie Knufinke-Meyfroyt, Carlo Lancia, Yentl Lodewijks, Simon Nienhuijs, Eva Deckers
Patient Experience Journal
Objective: The effectiveness of out of hospital lifestyle interventions in healthcare is likely co-dependent on social support from involved one's. We sought to investigate the interrelationships between patient-partner Co-responsibility, Spousal Support, and Self-efficacy and the mechanisms through which they contribute to health behaviors and outcomes relevant to weight loss and maintenance. Methods: Co-responsibility, Spousal Support, self-efficacy, health outcomes and health behaviors like total weight loss, physical activity, OBESI-Q, and health satisfaction were assessed through a questionnaire among 868 individuals attempting to lose weight. Full and semi-partial correlations were used to understand the association between Co-responsibility, Spousal Support, Self-efficacy …
The "Ableism'' Behind Mental Health Professionals' Perceptions Of Support, Hideki Muramatsu
The "Ableism'' Behind Mental Health Professionals' Perceptions Of Support, Hideki Muramatsu
Patient Experience Journal
This paper presents the personal narrative of the author, an individual who has experienced personal and clinical recovery from mental health difficulties. Diagnosed with a mental disorder (NEUROTIC; ICD-10) during my university years, I endured cognitive dysfunction, panic disorder, derangement of ego, suicidal ideation, and depression. Despite these challenges, I have actively engaged in social skills training, supervised virtual reality content, led self-help groups, and published papers on my experiences. I will discuss my own experiences as an expert-by-experience and describe the tendencies of professional ableism consciousness that I encountered during my journey of recovery. Through the lens of my …
Detecting Changes In Cancer-Related Cognitive Functioning Using Mixed-Effects Modeling And Study Design Simulations, Jonathan D. Clapp
Detecting Changes In Cancer-Related Cognitive Functioning Using Mixed-Effects Modeling And Study Design Simulations, Jonathan D. Clapp
USF Tampa Graduate Theses and Dissertations
The purpose of this dissertation is to utilize and compare two existing approaches for modeling nonlinear change in cognitive functioning in cancer patients over time and to assess alternative study designs to better capture chemotherapy-related cognitive impairment using simulation data. Using data from the Thinking and Living with Cancer study, trend analysis with orthogonal polynomials (OP) and piecewise (PW) regressions approaches used to analyze cognitive functioning trajectories. Simulated datasets tested the impact of study design parameters including measurement test-retest reliability (.6 or .8), sample size (100, 200, or 300), and the number of data collection time points (4 or 5) …