Digital Commons Network^™

Reduced Grey Matter Volume In Adolescents With Conduct Disorder: A Region‑Of‑Interest Analysis Using Multivariate Generalized Linear Modeling, Ru Zhang, Robert James R. Blair, Karina S. Blair, Matthew Dobbertin, Jaimie Elowsky, Johannah Bashford‑Largo, Ahria J. Dominguez, Melissa Hatch, Sahil Bajaj

Center for Brain, Biology, and Behavior: Faculty Publications

Background

Conduct disorder (CD) involves a group of behavioral and emotional problems that usually begins during childhood or adolescence. Structural brain alterations have been observed in CD, including the amygdala, insula, ventrolateral and medial prefrontal cortex, anterior cingulate cortex, and fusiform gyrus. The current study developed a multivariate generalized linear model (GLM) to differentiate adolescents with CD from typically developing (TD) adolescents in terms of grey matter volume (GMV).

Methods

The whole‐brain structural MRI data were collected from 96 adolescents with CD (mean age = 16.188 ± 1.259 years; mean IQ = 104.292 ± 8.107 ; 63 males) and 90 …

Language Nativeness Modulates Physiological Responses To Moral Vs Immoral Concepts In Chinese-English Bilinguals: Evidence From Event-Related Potential And Psychophysiological Measures, Fei Gao, Chenggang Wu, Hengyi Fu, Kunyu Xu, Zhen Yuan

Faculty, Staff and Student Publications

Morality has been an integral part of social cognition and our daily life, and different languages may exert distinct impacts on human moral judgment. However, it remains unclear how moral concept is encoded in the bilingual brain. This study, therefore, aimed to explore the emotional and cognitive involvement of bilingual morality judgement by using combined event-related potential (ERP) and psychophysiological (including skin, heart, and pulse) measures. In the experiment, thirty-one Chinese-English bilingual participants were asked to make moral judgments in Chinese and English, respectively. Our results revealed increased early frontal N400 and decreased LPC in L1 moral concept encoding as …

Informed Consent In Surgical Practice With Patients’ Experiences: A Cross-Sectional Study, Seda Kumru, Pakize Yiğit, Meryem Demirtaş, Hüseyin Fındık

Patient Experience Journal

This study aims to evaluate patients' experiences and perspectives regarding informed consent in surgical practice. Data for this cross-sectional study were collected from 276 patients using a questionnaire developed by Falagas et al. Descriptive statistics were employed for all questions. Statistical tests such as the Mann-Whitney U test, Kruskal-Wallis test, and Spearman's rank correlation analysis were performed, and Cohen's effect sizes were reported. IBM SPSS 23.0 was used for all analyses, and p<0.05 was considered statistically significant. A high score on both The Delivered Information Index and The Patient-Physician Index represents a positive informed consent process. Among the participants, 65.2% indicated that they understood all parts of the consent form. Of all patients, 92.8% reported that information about the specific surgical procedure was provided by physicians. However, 47.5% of the patients reported that they did not feel comfortable with their surgeons. The mean score of the Delivered Information Index was 5.63 (2.38). The mean patient-physician relationship score was 14.38 (3.31). There was a moderate positive correlation between the delivered information index and the patient-physician relationship (r=0.50; p<0.001). In addition, there was a moderate positive correlation between the delivered information index and the time spent on the informed consent process, as well as between the patient-physician relationship and the time spent on the informed consent process (r=0.52; r=0.40, respectively). The study emphasized the lack of communication between patients and physicians, the limitation of information on treatment risks, adverse effects, and alternative treatment options.

Experience Framework

This article is associated with the Policy & Measurement lens of The Beryl Institute Experience Framework (https://theberylinstitute.org/experience-framework/).

• Access other PXJ articles related to …

Patient Perspectives Of Health-Related Social Needs Screening In An Urban Academic Adult Primary Care Practice, Antony Nguyen, Joselvin Galeas, Jane Jih

Patient Experience Journal

Health-related social needs (HRSNs) affect health outcomes and healthcare utilization. Patients’ perspectives on the incorporation of HRSN screening in primary care settings is limited. We sought to explore adult primary care patient perspectives of HRSN screening from optional patient-provided free-text comments as part of a pilot self-administered HRSN screening survey on seven domains of HRSNs from the Accountable Health Communities HRSNs Screening Tool. The survey was available in English, Chinese or Spanish with a section titled “Comments” that invited patient respondents to provide anonymous free-text responses. We performed a thematic analysis of the written patient comments. Of the 679 participants …

An Slp Graduate Student’S Analysis Of Language In Children With Speech Sound Disorders, Madeline Janney, Donna Thomas

Journal of Interprofessional Practice and Collaboration

Purpose

Students in allied health professional (AHP) programs are instructed in evidenced-based evaluation practices and participate in interprofessional education and practice in order to identify disorders (e.g., speech, language, gross motor, fine motor) and provide effective treatment. The purpose of this paper is to present a small-scale research study of one graduate student in an AHP program that trains speech-language pathologists.

Method

A graduate student used retrospective methodology to examine the language skills of nine children with speech sound disorders (SSD) to determine if language impairment (LI) co-existed. The student learned and used a method of language sample analysis known …

Health-Related Quality Of Life Of Patients With Diabetes Mellitus And Covid-19 In Two University Teaching Hospitals In Nairobi County, Kenya, Purity Kibathi

MSc in Advanced Practice Nursing

Diabetes Mellitus corresponds with an increased risk of severe COVID-19 infection and high morbidity and mortality rates. Persons living with diabetes are more likely to encounter psychosocial problems such as depression, anxiety, and stress than the broader population. As the global pandemic unfolded, it was paramount to determine the health-related quality of life (QoL) and explore the experiences of patients with diabetes and COVID-19 to enable healthcare providers to recognize the components influencing HRQoL and identify the interventions to improve the health outcomes. The study was done to determine the health-related quality of life and experiences of patients with diabetes …

Sun Protection Behaviors And Skin Cancer Risk Among Children Of Color, Williana Magloire

Theses and Dissertations

Sun protection is beneficial for children of color as it decreases the risk for sunburns, hyperpigmentation, and most importantly, skin cancer. Invasive melanoma is commonly seen in children of color due to inadequate sun protection. Parental and caregiver modeling of sun protection behaviors may decrease the likelihood of skin cancer among children of color. The American Academy of Pediatrics (AAP, 2011) has suggested that pediatricians adopt the role of informing parents about the benefits of using sun protection products for their young children. They recommended that providers discuss sun protection behaviors with both the parent/child beginning at the age of …

Diversity, Equity, And Inclusion: Considerations In The Geriatric Emergency Department Patient, Anita N Chary, Lauren Cameron-Comasco, Kalpana N Shankar, Margaret E Samuels-Kalow

Faculty, Staff and Students Publications

This article introduces core topics in health equity scholarship and provides examples of how diversity, equity, and inclusion impact the aging population and emergency care of older adults. It offers strategies for promoting diversity, equity, and inclusion to both strengthen the patient-clinician therapeutic relationship and to address operations and systems that impact care of the geriatric emergency department patient.

A Deep Learning Approach For Transgender And Gender Diverse Patient Identification In Electronic Health Records, Yining Hua, Liqin Wang, Vi Nguyen, Meghan Rieu-Werden, Alex Mcdowell, David W Bates, Dinah Foer, Li Zhou

Faculty, Staff and Students Publications

Background: Although accurate identification of gender identity in the electronic health record (EHR) is crucial for providing equitable health care, particularly for transgender and gender diverse (TGD) populations, it remains a challenging task due to incomplete gender information in structured EHR fields.

Objective: Using TGD identification as a case study, this research uses NLP and deep learning to build an accurate patient gender identity predictive model, aiming to tackle the challenges of identifying relevant patient-level information from EHR data and reducing annotation work.

Methods: This study included adult patients in a large healthcare system in Boston, MA, between 4/1/2017 to …

Revascularization Impact: Quality Of Life Enhancement In Chronic Limb-Threatening Ischemia, Cristian Traian Paius, Vlad Denis Constantin, Alexandru Carap, Andrei Tarus, Grigore Tinica

Journal of Mind and Medical Sciences

Introduction. Globally, over 230 million people have peripheral artery disease, often undiagnosed, leading to chronic limb-threatening ischemia. Revascularization is vital for preventing amputation and improving quality of life. While specific questionnaires for severe ischemia are lacking, the SF-36 questionnaire is widely used to assess quality of life, with variations like SF-12 and SF-8 for larger cohorts. Objectives. Our aim was to assess how different lower limb revascularization methods affect the postoperative quality of life in patients with chronic limb-threatening ischemia. Methods. This study was conducted at the St. Pantelimon Emergency Hospital of Bucharest, Romania. It included 166 adult patients with …

Addressing Racism In Medicine With Community-Based Doula Services For Black Mothers, A Narrative Review Of The Literature And Historical Perspective, Brianna Roberts Canales, Emily Sloane

Marshall Journal of Medicine

No abstract provided.

Grammatical Parallelism In Aphasia: A Lesion-Symptom Mapping Study, William Matchin, Dirk B. Den Ouden, Alexandra Basilakos, Brielle Caserta Stark, Julius Fridriksson, Gregory Hickok

Communication Sciences and Disorders Faculty Articles and Research

Sentence structure, or syntax, is potentially a uniquely creative aspect of the human mind. Neuropsychological experiments in the 1970s suggested parallel syntactic production and comprehension deficits in agrammatic Broca’s aphasia, thought to result from damage to syntactic mechanisms in Broca’s area in the left frontal lobe. This hypothesis was sometimes termed overarching agrammatism, converging with developments in linguistic theory concerning central syntactic mechanisms supporting language production and comprehension. However, the evidence supporting an association among receptive syntactic deficits, expressive agrammatism, and damage to frontal cortex is equivocal. In addition, the relationship among a distinct grammatical production deficit in aphasia, …

Caregiver Perspectives On The Daily Function Of People Living With Hnrnph2-Related Neurodevelopmental Disorder: Developing A Conceptual Model, Rachel Salazar

Seton Hall University Dissertations and Theses (ETDs)

Introduction: Neurodevelopmental disorders are a group of conditions that start in childhood and lead to impairments in functioning. HNRNPH2-related neurodevelopmental disorder is an ultra-rare disorder in which individuals present with cognitive, behavioral, language and motor function impairments that often leads to reliance on their caregivers. Existing conceptual models of neurodevelopment are not specific to this ultra rare disorder and do not highlight the caregiver impact of living with HNRNPH2-related neurodevelopmental disorder.

Purpose: The purpose of this study is to understand the caregiver perspective on the everyday functioning of people living with HNRNPH2-related neurodevelopmental disorder to generate a …

12th International Conference On Business, Technology And Innovation 2023, University For Business And Technology - Ubt

UBT International Conference

Welcome to IC – UBT 2023

UBT Annual International Conference is the 12th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make …

Determining Call-To-Entry Rate And Recruitment Barriers In Clinical Studies For Community Clinics Serving Low-Income Populations: A Cohort Study, Elizabeth M Vaughan, Salim Virani, Mahmoud Al Rifai, Victor J Cardenas, Craig A Johnston, Laura Porterfield, Zuleica Santiago Delgado, Susan L Samson, Vanessa Schick, Aanand D Naik

Faculty, Staff and Student Publications

BACKGROUND: Recruitment for clinical studies is challenging. to overcome barriers, investigators have previously established call-to-entry rates to assist in planning. However, rates specific to low-income minority populations are needed to account for additional barriers to enrolment these individuals face.

OBJECTIVE: to obtain a call-to-entry rate in a low-income uninsured Hispanic population with chronic disease.

METHODS: We used data from four of our randomised clinical studies to determine the call-to-entry rate for individuals (n=1075) with or at risk for type 2 diabetes: participants needed/potential participants contacted=recruitment rate (yield). Research staff contacted potential participants to enrol in a study that evaluated 6 …

Does Community Of Practice Theory Apply To Virtual Postgraduate Surgical Training?, Sherif Elnikety, Eman Badr

Health Professions Education

Postgraduate surgical training has evolved over centuries as a result of changes in the community, advances in medicine, technological innovations, and the theoretical basis of training and education. The recent pandemic has had a significant effect on postgraduate surgical training. Training has been provided virtually, which has negatively affected the relationship between trainers and trainees. While virtual training has provided a solution for geographical barriers, it did not provide a similar training experience compared to face-to-face interactions. Technical skills, in particular, were extremely difficult to teach virtually. Although the COVID-19 pandemic is over, and daily life is returning to normality, …

Association Of Social Vulnerability And Covid-19 Mortality Rates In Texas Between 15 March 2020, And 21 July 2022: An Ecological Analysis, Dennis Ogeto Nyachoti, Nalini Ranjit, Ryan Ramphul, Leah D Whigham, Andrew E Springer

Faculty, Staff and Student Publications

BACKGROUND: Despite the key role of social vulnerability such as economic disadvantage in health outcomes, research is limited on the impact of social vulnerabilities on COVID-19-related deaths, especially at the state and county level in the USA.

METHODS: We conducted a cross-sectional ecologic analysis of COVID-19 mortality by the county-level Minority Health Social Vulnerability Index (MH SVI) and each of its components in Texas. Negative binomial regression (NBR) analyses were used to estimate the association between the composite MH SVI (and its components) and COVID-19 mortality.

RESULTS: A 0.1-unit increase in the overall MH SVI (IRR, 1.27; 95% CI, 1.04-1.55; …

The Validity And Reliability Of The Diabetic Foot Scale-Short Form (Dfs-Sf) In The Turkish Population: A Methodological Study, Meryem Kiliç, Ayi̇şe Karadağ, Neşe Koçakgöl

Turkish Journal of Medical Sciences

Background/aim: Diabetic foot ulcers (DFUs) cause decreased quality of life due to prolonged hospital stay, loss of workforce, disabilities, psychological trauma, and increased healthcare costs. This study aims to assess the validity and reliability of the Diabetic Foot ScaleShort Form (DFS-SF) for Turkish-speaking individuals with DFUs. Materials and methods: This was a methodological study conducted with 174 Turkish patients with DFUs from March 2020 to December 2020. Translation?back translation was performed for language equivalence and expert opinions were obtained for content validity. The scale?s construct validity was tested with confirmatory factor analysis, exploratory factor analysis, and known-group validity. Cronbach?s alpha …

Validity And Reliability Study Of The Quality Of Recovery Scale In Turkish, Ümmühan Kiliç, Di̇lek Kiymaz, Esra Saraçoğlu, Bahadir Yazicioğlu

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to adapt the ?Quality of Recovery-15 Scale?, developed to measure the postoperative recovery quality of individuals, into Turkish by carrying out validity and reliability studies. Materials and methods: This methodological study was conducted with a total of 150 patients who underwent surgery under general anesthesia between November 2021 and January 2022 in a training and research hospital in the Black Sea region. Data was collected from the patients through the face-to-face interview method before the operation, on the 24th and the 48th hour postoperatively. First, the linguistic validity of the scale and then …

Community Health Worker Program: Chronic Non-Communicable Diseases In Children, Julia L. Newell

DNP Qualifying Manuscripts

Abstract

Background: Childhood obesity, asthma, and untreated mental health conditions, are three examples of chronic non-communicable diseases (CNDs) that pose a host of negative consequences later in life. Community health workers (CHWs) are in a unique position to address these negative health externalities by leveraging linguistic, cultural, and socioemotional connectedness within their communities.

Local Problem: Minority children in the Central Valley of California, face additional risk factors for the development of CNDs. CHWs working in this area require enhanced training on CNDs to improve their practice.

Methods: In partnership with Save the Children (STC), the University of San Francisco (USF) …

The Tardigrade Damage Suppressor Protein Dsup Promotes Dna Damage In Neurons, Elliot Murphy, Kiefer J Forseth, Cristian Donos, Kathryn M Snyder, Patrick S Rollo, Nitin Tandon

Faculty, Staff and Student Publications

Language depends critically on the integration of lexical information across multiple words to derive semantic concepts. Limitations of spatiotemporal resolution have previously rendered it difficult to isolate processes involved in semantic integration. We utilized intracranial recordings in epilepsy patients (n = 58) who read written word definitions. Descriptions were either referential or non-referential to a common object. Semantically referential sentences enabled high frequency broadband gamma activation (70-150 Hz) of the inferior frontal sulcus (IFS), medial parietal cortex, orbitofrontal cortex (OFC) and medial temporal lobe in the left, language-dominant hemisphere. IFS, OFC and posterior middle temporal gyrus activity was modulated by …

Causal Models And Causal Modelling In Obesity: Foundations, Methods And Evidence, Roger S Zoh, Xiaoxin Yu, Philip Dawid, George Davey Smith, Stephen J French, David B Allison

Children’s Nutrition Research Center Staff Publications

Discussing causes in science, if we are to do so in a way that is sensible, begins at the root. All too often, we jump to discussing specific postulated causes but do not first consider what we mean by, for example, causes of obesity or how we discern whether something is a cause. In this paper, we address what we mean by a cause, discuss what might and might not constitute a reasonable causal model in the abstract, speculate about what the causal structure of obesity might be like overall and the types of things we should be looking …

Addressing Equity Asymmetries In General Chemistry Outcomes Through An Asset-Based Supplemental Course., Hannah Sevian, Tyson D King-Meadows, Klaudja Caushi, Tamari Kakhoidze, Jessica M Karch

Faculty, Staff and Students Publications

Undergraduate first-semester general chemistry (GC1) functions as a gatekeeper to STEM degrees, asymmetrically impacting students who are nonwhite, from lower socioeconomic groups, non-native English speakers, two-year college transfers, and first-generation in college. Nationally, just under 30% of students earn grades of D, F, or withdraw (termed DFW) in GC1; however, DFW rates are much higher for subgroups underrepresented in STEM occupations. Socioeconomic inequalities tend to increase over an individual's lifetime due to the magnification of cumulative disadvantage. Because undergraduate degrees correlate with higher employment and STEM occupations correlate with higher earnings, GC1 represents a critical path point where disparities can …

Physical Activity And Mental Health Of Youth During The Covid-19 Pandemic, Amber Watson, Alicia Fedewa, Clair Tischner

International Journal of Physical Activity and Health

The COVID-19 Pandemic has globally impacted children’s physical activity and mental health outcomes since the transition to remote learning (Štveráková, et al., 2021). Children and adults may encounter negative mental health related consequences, higher stress, and a significant lack of physical activity while in physical and social isolation (Clemente-Suárez, 2022). In particular, school-aged children have experienced a significant reduction in physical activity since transitioning to remote learning and do not have sufficient opportunities to make up for this loss while engaged in remote learning (Štveráková, et al., 2021). Increased physical activity has been consistently correlated with positive mental health outcomes …

Core Vocabulary Intervention For Language-Delayed Kindergarten Students Using Augmentative And Alternative Communication, Angela M. Riccelli, Ravi Nigam

Journal of Applied Disciplines

The purpose of this study was to measure the impact of core vocabulary selection and the subsequent usage of a prescribed core vocabulary intervention over a period of one trimester (13-week period) and to report its impact on the overall communicative effectiveness of kindergarten students with language delay using augmentative and alternative communication (AAC). Study participants were provided with a pretest, speech and language therapy sessions in which intervention took place, and a posttest, which was administered by a speech–language pathologist. Intervention implementation commenced at the beginning of the school year and extended through the end of the trimester.13-week period. …

Evaluation Of Telephone Cardiopulmonary Resuscitation Performance In Current Practice In Saudi Arabia, Meshary Binhotan, Joanne Turnbull, Graham Petley, Nawfal Aljerian, Mohammad Altuwaijri

Journal of the Saudi Heart Association

Objectives: Out-of-hospital cardiac arrest (OHCA) is a global health problem with a low survival rate. Telephone cardiopulmonary resuscitation (T-CPR) guidance by emergency medical services (EMS) dispatchers can improve CPR performance and, consequently, survival rates. Accordingly, the American Heart Association (AHA) has released performance standards for T-CPR in current practice to improve its quality. However, no study has examined T-CPR performance in Saudi Arabia. Therefore, this study aims to evaluate T-CPR performance in the Saudi Arabian EMS system.

Methods: A retrospective observation of OHCA calls in current practice was conducted in Riyadh, Saudi Arabia. OHCA calls were reviewed to identify those …

Telling Stories In Noise: The Impact Of Background Noises On Spoken Language For People With Aphasia, Tyson G. Harmon, Brenna Scadden Nelson, Christopher Dromey, Kirsten Dixon Clawson

Faculty Publications

Purpose: Determine how different background noise conditions affect the spoken language of participants with aphasia during a story retell task.

Method: Participants included 11 adults with mild to moderate aphasia and 11 age- and gender-matched controls. Participants retold stories in a silent baseline and five background noise conditions (conversation, monologue, phone call, cocktail, pink noise). Dependent measures of speech acoustics (fundamental frequency, mean intensity), speech fluency (speech rate, disfluent words), and language production (correct information units, lexical errors, lexical diversity, and cohesive utterances) were compared between groups and across conditions.

Results: Background noise resulted in higher fundamental frequency (F_{0 …}

Physiological Arousal, Attentiveness, Emotion, And Word Retrieval In Aphasia: Effects And Relationships, Tyson G. Harmon, Angela Johnson, Vivian Ward, Shawn Nissen

Faculty Publications

Purpose: To (a) compare physiological arousal and attentiveness during a confrontational naming task between participants with aphasia and a control group across four conditions that varied according to emotionality of presented stimuli and (b) explore relationships among physiological arousal, attentiveness, perceived arousal, and naming performance. We hypothesized that participants with aphasia would show lower levels of arousal and attentiveness than control participants and that emotional conditions would lead to increased physiological arousal and attentiveness.

Method: Eight participants with aphasia and 15 control participants completed a confrontational naming task under positive, negative, and neutral conditions and rated their perceived arousal after …

Quantitative Gender And Ethnicity Differences In Emergency Medicine Residency Applications, Steven Jay Warrington

Doctoral Dissertations and Projects

The purpose of this quantitative causal-comparative study is to examine if gender affects a medical student’s electronic Standardized Letters of Evaluation, or the characteristics of language used, in their application materials to an emergency medicine residency program through the Electronic Residency Application Service. This study is important as research is needed to determine if there is a difference in ratings or language used in emergency residency applications based on a medical student’s gender. The participants include 173 applicants from the 2022-2023 cycle that submitted material to a single emergency medicine residency program through the Electronic Residency Application Service. Instruments used …

Generalization Of Procedural Motor Sequence Learning After A Single Practice Trial, B P Johnson, I Iturrate, R Y Fakhreddine, M Bönstrup, E R Buch, E M Robertson, L G Cohen

2020-Current year OA Pubs

When humans begin learning new motor skills, they typically display early rapid performance improvements. It is not well understood how knowledge acquired during this early skill learning period generalizes to new, related skills. Here, we addressed this question by investigating factors influencing generalization of early learning from a skill A to a different, but related skill B. Early skill generalization was tested over four experiments (N = 2095). Subjects successively learned two related motor sequence skills (skills A and B) over different practice schedules. Skill A and B sequences shared ordinal (i.e., matching keypress locations), transitional (i.e., ordered keypress pairs), …