Digital Commons Network^™

Integration Of Cognitive Processing Therapy For Ptsd And Cognitive-Behavioral Therapy For Co-Occurring Alcohol Use Disorder: Design And Methodology Of A Randomized Controlled Trial, Anka A Vujanovic, Sudie E Back, Debra L Kaysen, Amber M Jarnecke, Kat Roberts, Fiorela Ruiz, Kayla E Hall, Julianne C Flanagan, Joy M Schmitz, Sonya B Norman, Lyndsey Zoller, Patricia A Resick

Faculty, Staff and Student Publications

Background: The prevalent comorbidity of alcohol use disorder (AUD) with posttraumatic stress disorder (PTSD) is characterized by more severe symptomatology, greater functional impairment, increased suicide risk, and poorer treatment outcomes as compared to either disorder alone. Trauma-focused, cognitive-behavioral interventions delivered alongside interventions for substance use disorders are recommended to reduce PTSD severity and substance use. Cognitive Processing Therapy (CPT) for PTSD and cognitive-behavioral therapy (i.e., Relapse Prevention [RP]) for AUD are two of the most widely used and efficacious treatments for these conditions. There are few effective integrated treatments available for PTSD/AUD comorbidity. The present study addresses this critical gap …

Stimulant Medications And Bone Health, Christine M Swanson, Julie H Wolfe, Chadi A Calarge

Faculty, Staff and Students Publications

Purpose of review: This review summarizes the potential impact of stimulant medications on bone health, to raise awareness and optimize their safe use.

Recent findings: Stimulant medications can impair bone health through inadequate nutrient/calorie intake and stimulation of the sympathetic nervous system, which regulates bone metabolism. However, their use decreases fracture risk in younger populations ([Formula: see text]25 years old) with attention deficit/hyperactivity disorder (ADHD), likely through reductions in impulsivity and injury. Special care may be needed when fractures occur while using these medications, as recent data suggest psychostimulants are associated with impaired fracture healing. Prescription and non-prescription use of …

Comparison Of Efficacy Of Autologous Platelet Rich Plasma Versus Silicone Products For Treatment Of Scars, Sanjay Kumar Giri, Ahana Bandyopadhyay, Santanu Suba, Sweta Singh, Bramhadatta Pattnaik, Gaurav Chhabra

Sultan Qaboos University Medical Journal

Objectives: This study aimed to compare the efficacy of intralesional autologous platelet rich plasma (PRP) injection in post-traumatic and post-surgical scars to a control group managed with silicone-based products. In addition, this study aimed to determine the success rate via aesthetic result, symptom improvement and outcome in terms of complications using autologous PRP on scars caused by burns or trauma. Methods: This randomised controlled trial study was conducted from August 2022 and February 2024 at the Departments of Burns and Plastic Surgery, Surgical Gastroenterology and Obstetrics and Gynaecology, AIIMS, Bhubaneswar, India. Intralesional autologous PRP injections were administered to post-traumatic or …

Cigarette And E-Cigarette Use In Greater Philadelphia: Proportion Of Use Compared To National Data And Local Predictors Of Smoking Status, Munjireen Sifat, Joshua Banks, Lilianna Phan, Kuang-Yi Wen, Julie A. Barta, Rebecca J. Melillo, Hee-Soon Juon

College of Population Health Faculty Papers

UNLABELLED: Objective tobacco use, cigarette, e-cigarette, cancer-related beliefs, perceived risk, lifestyle attribution, cancer disparities, health equity. We assessed cigarette smoking and e-cigarette use in the Greater Philadelphia region alongside national data. The objectives were to descriptively explore differences in tobacco use by sociodemographic characteristics. We also examined cancer belief associations with smoking and e-cigarette use in the local context.

METHODS: We descriptively compared cross-sectional survey data from 2744 adults in the Sidney Kimmel Comprehensive Cancer Center (SKCCC) catchment area (Greater Philadelphia region; May-July 2022) with 6252 Health Information National Trends Survey (HINTS 6) nationally representative respondents (United States; March-November 2022). …

Reducing Catheter-Associated Urinary Tract Infections Through Staff Education In A Nursing Home Setting, Aderonke Abimbola Abatan

Walden Dissertations and Doctoral Studies

No abstract provided.

Staff Education To Improve Staff Knowledge And Confidence In Delivering Sleep Education And Administering Sleep Quality Assessment Tools, Beverly Britton

Walden Dissertations and Doctoral Studies

No abstract provided.

Contemporary Management Of Acute Heart Failure: From Emergency Presentation To Long-Term Remission, Jolie Bruno, Mattia Arrigo, Guillaume Baudry, Jan Biegus, Biykem Bozkurt, Kamilė Čerlinskaitė-Bajorė, Laura P Cohen, Nick Hartshorne-Evans, Shiro Ishihara, Neusa Jessen, Pieter Martens, Peder Myhre, Matteo Pagnesi, Carolyn Rosner, Novi Yanti Sari, Gianluigi Savarese, Kristoffer Grundtvig Skaarup, Aferdita Spahillari, Jozine M Ter Maaten, Heli Tolppanen, Jim L Januzzi, Alexandre Mebazaa

Faculty, Staff and Students Publications

Acute heart failure (AHF) represents a major global health challenge, with a substantial impact on survival, morbidity, and health care resource utilization. The clinical and economic burden associated with this condition continues to grow, highlighting the need for a timely, structured, and patient-centered approach to care. In light of the expanding body of data and evidence accumulated over recent years, it is necessary to rethink how we approach the recognition and management of AHF. This need has motivated the development of the present review, which aims to provide an updated and practical synthesis of the management of AHF-from early diagnostic …

Cardiac Hdac3 Disruption Contributes To Hdac Inhibitor-Induced Qt Prolongation, Jiao Lu, Christopher Ward, Sichong Qian, Lilei Zhang, Jiang Chang, Zheng Sun

Faculty, Staff and Students Publications

Histone deacetylase (HDAC) inhibitors are approved for cancer treatment and are being investigated for a wide range of other diseases. Despite their therapeutic promise, clinical studies have reported cardiac side effects, particularly electrocardiogram (EKG) abnormalities, with QT interval prolongation being one of the most consistently reported findings. The mechanisms underlying these cardiac effects remain unclear. In this study, we investigated the role of HDAC3 in cardiac electrophysiology. We found that postnatal depletion of cardiac HDAC3 in mice caused QT interval prolongation, recapitulating the EKG abnormalities reported with HDAC inhibitor use. Adult-onset inducible depletion of cardiac HDAC3 induced additional EKG abnormalities, …

Correction: Watts Et Al. Multi-Antigen Elephant Endotheliotropic Herpesvirus (Eehv) Mrna Vaccine Induces Humoral And Cell-Mediated Responses In Mice, Jessica R Watts, Jennifer L Spencer Clinton, Jeroen Pollet, Rongsheng Peng, Jie Tan, Paul D Ling

Faculty, Staff and Students Publications

The authors would like to make the following corrections to this published paper [...].

A Size-Structured Approach For Modeling Coral-Algal Dynamics, Anayse Miller, Julie C. Blackwood, Lauren M. Childs

Biology and Medicine Through Mathematics Conference

No abstract provided.

Computation Models Of The Primary Auditory Cortex, Jonathan Gonzalez Martinez, Quynh-Anh Nguyen

Biology and Medicine Through Mathematics Conference

No abstract provided.

Geometry-Driven Changes In Pressure And Flow Dynamics In Control And Coarcted Aortic Hemodynamics, Md Arifuzzaman, Mette Olufsen, Mansoor Haider

Biology and Medicine Through Mathematics Conference

No abstract provided.

Computational Fluid Dynamics Model For Assessing Surgical Strategies For Liver Shunt Closure In Dogs, Schuyler Brennan, Nathan Nelson, Mette Olufsen

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling The Effects Of Chronic Stress On Type 2 Diabetes, Kris Mae Pasia

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Mechanistic Model Of Adhesion, Inflammation, Sleep, And Pain In Sickle Cell Patients, Milan Marsh, Rebecca Segal

Biology and Medicine Through Mathematics Conference

No abstract provided.

Positive Affect And Sleep Quality As Predictors Of Pain Onset In Pediatric Sickle Cell Patients, Eunice Clark, Reginald Mcgee, Cecelia Valrie, Rebecca Segal, Angela Reynolds

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Logic-Based Differential Equation Model Of Endothelial Cell Function, Ella Froedge, Scarlett Hamilton, Mitchel Colebank

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Multiscale Computational Framework Coupling Pulmonary Arterial Blood Flow And Lung Tissue Perfusion, Nigar Sultana, Hangjie Ji, Mette Sofie Olufsen

Biology and Medicine Through Mathematics Conference

No abstract provided.

Understanding Dengue Spread In Córdoba, Argentina Through Spatial Epidemiological Modeling, Mohammad Mihrab Uddin Chowdhury

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling Serotonin Metabolism Towards A Diagnostic Skin Test For Depression, Joel Greenfield

Biology and Medicine Through Mathematics Conference

No abstract provided.

Comparing Mathematical Models Of Systemic Infection Responses, Laura M. Witzel

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Phylogeny Informed Mathematical Model Of Hpai H5n1 Transmission And Control In Multi Host Systems, Oluwatosin Babasola

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematical Modeling Of A Coral-Symbiont System To Assess Heat-Induced Bleaching, Anna Zittle, Angela Reynolds, Rebecca Segal, Liza Roger, Nastassja Lewinski

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematical Modeling Of The Combined Effects Of Thermal Burn And Local Irradiation, Quintessa Hay, Rachel Jennings, Amy Creel, Kyle Gaffney, Christina Wagner, Kidist Maxwell, Ginu Unnikrishnan, Tyler Dant

Biology and Medicine Through Mathematics Conference

No abstract provided.

Parameter Sensitivity, Identifiability, And Estimation For A Data-Driven Model Of Malaria, Katharine Gurski, Kathleen Hofman

Biology and Medicine Through Mathematics Conference

No abstract provided.

Data-Driven Modeling Approaches For Epidemiological Applications Using County-Level Data, Mansoor A. Haider

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mechanistic Basis Of Post-Treatment Control Of Shiv After Huad5sivgag/Tat, And1 Pgt121 Therapy2, Sirawit A. Srakaew

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling The Dynamics Of Infectious Disease Transmission Through Wastewater Surveillance: Applications To Covid-19 Epidemiology, Ephraim Agyingi, Michael Kostrna

Biology and Medicine Through Mathematics Conference

No abstract provided.

Impact Of The Dose And The Number Of Transmitted/Founder Viruses On Siv Dynamics, Sunil Maity, Vitaly V. Ganusov

Biology and Medicine Through Mathematics Conference

No abstract provided.

Turf Toe And Sesamoid Fracture Case Study, Mason Cannon

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE This case presents the evaluation and management of a 15-year-old male multi-sport high school athlete. The athlete initially sustained a turf toe injury that progressed into a sesamoid fracture. This report showcases the clinical findings, treatment progression, and outcomes within a disablement model framework.