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Articles 2461 - 2490 of 326301
Full-Text Articles in Entire DC Network
Congenital Heart Disease In Infants Of Diabetic Mothers (Pediatrics Hospital Based Study), Esraa Ali Mathboob Mahdi, Basil M. Hanudi
Congenital Heart Disease In Infants Of Diabetic Mothers (Pediatrics Hospital Based Study), Esraa Ali Mathboob Mahdi, Basil M. Hanudi
Iraqi Postgraduate Medical Journal
Background: Infants born to diabetic mothers are at elevated risk for neonatal complications, including metabolic, hematologic, respiratory, cardiac, and neurological disorders. Notably, insulin-dependent diabetes increases the likelihood of congenital heart diseases (CHDs). Aim: This study aimed to determine the incidence and associated factors of cardiac complications among neonates born to diabetic mothers and to identify the prevalent patterns of congenital heart defects in this population. Methods: An analytical cross-sectional study was conducted over a 10-month period (July 1, 2020 to April 30, 2021) at the Neonatal Care Unit of Child’s Central Teaching Hospital. The study included 100 neonates admitted within …
Effectiveness Of Vocational Therapy On Psychotic Symptoms Of Patients With Schizophrenia, Iman Ahmed Jumaa, Naamah Shlaibah Humaidi
Effectiveness Of Vocational Therapy On Psychotic Symptoms Of Patients With Schizophrenia, Iman Ahmed Jumaa, Naamah Shlaibah Humaidi
Iraqi Postgraduate Medical Journal
AbstractBackground: Schizophrenia is a severe mental disorder often resulting in significant functional impairment. While antipsychotic medications are the cornerstone of treatment, complementary therapies are needed to address residual symptoms and improve functional outcomes.Aims and Objectives: This study aimed to evaluate the effect of adding a structured vocational therapy program to standard drug therapy in patients with schizophrenia.Materials and Methods: A prospective was conducted with 100 inpatients at Al-Rashad Hospital. Participants were divided into two cohorts: an intervention cohort (n=50) that received vocational therapy plus drug therapy and a control cohort (n=50) that received drug therapy alone. The Positive and Negative …
Association Between Cesarean Scar Niche Characteristics And Menstrual Irregularities: A Cross-Sectional Study, Ridab Ali Saeed, Ahmed R. Shaker
Association Between Cesarean Scar Niche Characteristics And Menstrual Irregularities: A Cross-Sectional Study, Ridab Ali Saeed, Ahmed R. Shaker
Iraqi Postgraduate Medical Journal
ABSTRACT:Background: Cesarean section is a prevalent obstetric procedure with potential complications, including the formation of uterine niches or isthmoceles. These defects are associated with irregular menstrual cycles and adverse gynecological outcomes.Aim of the Study: To evaluate the association between cesarean scar niches and menstrual irregularities, and examine whether niche size and myometerial thickness are linked to menstrual irregularities.Patients and Methods: This cross-sectional observational study included 200 women with a history of cesarean section. Participants were divided into regular and irregular menstrual cycle groups and further categorized by the presence or absence of uterine niches. Clinical and demographic data were collected, …
Neonatal And Maternal Outcomes In Pregnancies With Sonographically Diagnosed Nuchal Cord: A Prospective Cohort Study, Eman Muhammad Ramadan, Samar Sarsam
Neonatal And Maternal Outcomes In Pregnancies With Sonographically Diagnosed Nuchal Cord: A Prospective Cohort Study, Eman Muhammad Ramadan, Samar Sarsam
Iraqi Postgraduate Medical Journal
ABSTRACT:Background: Nuchal cords, where the umbilical cord encircles the fetal neck, are a common obstetric finding, potentially impacting neonatal and maternal outcomes. Their clinical significance remains debated.Aim of the Study: To evaluate the prevalence of nuchal cords in pregnancies at Al Elwiya maternity teaching hospital and to evaluate the association between nuchal cord presence and effects on neonatal and maternal outcomes.Patients and Methods: A prospective, single-center, cohort study was conducted at Al-Elwiya Maternity Teaching Hospital from first of January to first of December 2024. It included 600 pregnant women in the study 107 had an ultrasound diagnosed with nuchal cords. …
Use Of The Bethesda System For Reporting Thyroid Cytopathology In Thyroid Nodules Incoordination To The Appropriate Surgical Intervention, Rusul Abid Kareem, Basim Rassam Ghadhban
Use Of The Bethesda System For Reporting Thyroid Cytopathology In Thyroid Nodules Incoordination To The Appropriate Surgical Intervention, Rusul Abid Kareem, Basim Rassam Ghadhban
Iraqi Postgraduate Medical Journal
Background: The thyroid nodule refers to an abnormal growth of thyroid cells. Although the vast majority of thyroid nodules are benign, a small proportion of thyroid nodules are malignant. In order to diagnose and treat malignant thyroid nodules at the earliest stage, most of them need radiological and cytological evaluation. Fine-needle aspiration (FNA) using The Bethesda System for reporting thyroid cytopathology.Aim of study: To evaluate the significance of the Bethesda classification in detecting malignant thyroid nodule and relate the appropriate surgical intervention accordingly.Methods: prospective, case control study was conducted in Baghdad teaching hospital, 2nd floor. from 1st of December 2021 …
The Role Of Apparent Diffusion Coefficient Value Measurement In The Differentiation Of Ischemic Stroke From Multiple Sclerosis In The Brain, Jenan Mohammed Khalid, Amer Murad Gebur
The Role Of Apparent Diffusion Coefficient Value Measurement In The Differentiation Of Ischemic Stroke From Multiple Sclerosis In The Brain, Jenan Mohammed Khalid, Amer Murad Gebur
Iraqi Postgraduate Medical Journal
Differentiating acute ischemic stroke from active multiple sclerosis (MS) plaques using conventional MRI can be challenging due to overlapping radiological features. The Apparent Diffusion Coefficient (ADC) provides a quantitative measure of water diffusion, potentially offering a solution to this diagnostic dilemma. This study aims to evaluate the role of ADC value measurements in distinguishing between acute ischemic stroke and acute demyelinating MS lesions. This cross-sectional study was conducted at a tertiary care center in Iraq from November 2024 to July 2025. All participants underwent a standardized brain MRI protocol on a 1.5-T scanner. ADC values were measured by manually placing …
Evaluating The Usefulness Of 24-Hour Video Eeg Monitoring In Dr. Sa’Ad Alwitry’S Hospital, Baghdad, Iraq, Ebtehal Dhiyaa, Akram Mohammad Al-Mahdawi, Muataz Fairooz Abd
Evaluating The Usefulness Of 24-Hour Video Eeg Monitoring In Dr. Sa’Ad Alwitry’S Hospital, Baghdad, Iraq, Ebtehal Dhiyaa, Akram Mohammad Al-Mahdawi, Muataz Fairooz Abd
Iraqi Postgraduate Medical Journal
Background: Video electroencephalography (VEEG) monitoring, which combines EEG with synchronized video recording, is a valuable but resource-intensive tool for evaluating seizure disorders. While its role in diagnosis and classification is established, its specific impact on altering provisional diagnoses and guiding treatment remains underexplored.Objective: To assess the diagnostic utility of 24-hour inpatient VEEG monitoring in confirming or modifying provisional diagnoses and reducing misdiagnosis in patients with paroxysmal events.Methods: A retrospective analysis was conducted on 192 patients who underwent VEEG monitoring at Dr. Saad Alwitry Hospital between January and December 2018. Patient records were reviewed to assess the impact of VEEG on …
Esophageal Stricture Post Congenital Tracheoesophageal Fistula Repair, Zaid A. Zaid, Momtaz Al-Nima
Esophageal Stricture Post Congenital Tracheoesophageal Fistula Repair, Zaid A. Zaid, Momtaz Al-Nima
Iraqi Postgraduate Medical Journal
Background: It’s a narrowing of > 50% of the esophagus lumen or as a narrowing detected on a contrast study , or at esophagostomy in combination with symptomsTracheoesophageal fistula (TEF) is a relatively rare congenital anomaly occurring in one in 2500-3000 live births (3)Moreover, the life expectancy of the patients without proper treatment may be measured in weeksAim of study: evaluation of the demographics, surgical details, and postoperative outcomes of pediatric patients undergoing surgery for Tracheoesophageal Fistula (TEF) repair.Methods: The study was conducted at Pediatric Teaching Hospital/Medical City from December, 2022, to November , 2023. A total of 35 cases post …
Immunohistochemical Expression Of Estrogen Receptor In Papillary Thyroid Carcinoma With Lymph Node Metastasis, Furqan J. Albderi, Kaswer M. Altoriahi
Immunohistochemical Expression Of Estrogen Receptor In Papillary Thyroid Carcinoma With Lymph Node Metastasis, Furqan J. Albderi, Kaswer M. Altoriahi
Iraqi Postgraduate Medical Journal
Background: Papillary thyroid carcinoma (PTC) is the most common well-differentiated thyroid malignancy. The female predominance of PTC suggests a potential role for estrogen signaling, mediated through estrogen receptors (ER), in thyroid carcinogenesis and progression.Objective: This study aimed to evaluate estrogen receptor protein expression in papillary thyroid carcinoma with lymph node metastasis and to analyze its association with clinicopathological parameters.Methods: A retrospective study was conducted on 50 formalin-fixed, paraffin-embedded thyroid and corresponding lymph node tissue specimens from Iraqi patients with PTC and lymph node metastasis. ER expression was assessed by immunohistochemistry. Associations between ER expression and clinicopathological variables were analyzed using …
Evaluation Of Peripheral Nerves In Patients With Acromegaly By Electrodiagnostic Study, Taiseer Saad Musa, Farqad Bader Hamdan, Abbas Mahdi Rahmah
Evaluation Of Peripheral Nerves In Patients With Acromegaly By Electrodiagnostic Study, Taiseer Saad Musa, Farqad Bader Hamdan, Abbas Mahdi Rahmah
Iraqi Postgraduate Medical Journal
Background: Acromegaly is a rare multisystem disorder caused by excess growth hormone (GH) and insulin-like growth factor 1 (IGF-1), typically from a pituitary somatotroph adenoma. Neurological complications, particularly peripheral neuropathies, are common but under-investigated.Objectives: To evaluate peripheral nerve involvement in Iraqi patients with acromegaly and assess the impact of IGF-1 levels, disease duration, adenoma size, and other clinical variables on nerve function.Methods: A cross-sectional study included 41 acromegalic patients (≥25 years) who underwent detailed neurophysiological testing. Patients were classified as metabolically controlled or uncontrolled based on IGF-1 levels.Results: IGF-1 and GH levels were significantly lower in the controlled group (p<0.001), while other clinical variables showed no significant differences. Neurophysiological findings revealed significantly reduced sensory and motor amplitudes, prolonged latencies, and slower conduction velocities in the uncontrolled group. IGF-1 levels correlated positively with sensory and motor latencies and negatively with conduction velocities and CMAP amplitudes. Larger adenoma size and presence of diabetes were also associated with worse nerve parameters. Deep X-ray therapy and surgical excision showed beneficial associations with median nerve conduction velocity.Conclusion: Peripheral nerve dysfunction, including carpal tunnel syndrome and polyneuropathy, is more severe in metabolically uncontrolled acromegaly. Macroadenomas and poor biochemical control are linked with worse neurophysiological outcomes.
Family Medicine In Iraq: Bridging The Gap Between Training And Practice For Health System Reform, Eman A. Al-Kaseer
Family Medicine In Iraq: Bridging The Gap Between Training And Practice For Health System Reform, Eman A. Al-Kaseer
Iraqi Postgraduate Medical Journal
No abstract provided.
Caregiver Health Literacy Is Associated With Pediatric Burn Recovery Outcomes, Ananya Sampathkumar, Anna Sabukurian, Erin M. Morris, Alyssa M. Griffith, Nicholas A. Long, Alexa Cumming, Macie Boden, Christina G. Morris, Lauren K. Mayon, Thian H. Nguyen, Allison L. Speer, Natalie A. Drucker
Caregiver Health Literacy Is Associated With Pediatric Burn Recovery Outcomes, Ananya Sampathkumar, Anna Sabukurian, Erin M. Morris, Alyssa M. Griffith, Nicholas A. Long, Alexa Cumming, Macie Boden, Christina G. Morris, Lauren K. Mayon, Thian H. Nguyen, Allison L. Speer, Natalie A. Drucker
Summer Research Program Abstracts
No abstract provided.
The Role Of The Hs1582 Enhancer In The Regulation Of Spry1 In Human Neural Crest Cells, Maia Williams, Vershanna E Morris
The Role Of The Hs1582 Enhancer In The Regulation Of Spry1 In Human Neural Crest Cells, Maia Williams, Vershanna E Morris
Summer Research Program Abstracts
No abstract provided.
July 2026 Mda At Your Service — Who Can Supervise Dental Assistant Radiography Training In Michigan?, Mda Membership Department Staff
July 2026 Mda At Your Service — Who Can Supervise Dental Assistant Radiography Training In Michigan?, Mda Membership Department Staff
The Journal of the Michigan Dental Association
This Q&A feature provides practical guidance on common professional and licensing questions for Michigan dentists. It clarifies that any licensed dentist can supervise required dental assistant radiography training, highlighting the MDA's online program. The article also offers advice for new dentists looking to connect with colleagues through local societies and the "New Doc Connection" online hub. Additionally, it outlines the mandatory steps for updating a professional license after a legal name change and directs members to valuable MDA resources for navigating dental insurance contracts and third-party payer agreements.
July 2026 The Back Page — Fighting Burnout By Building A Better Sense Of Community, Tamar Shrikian, Dmd
July 2026 The Back Page — Fighting Burnout By Building A Better Sense Of Community, Tamar Shrikian, Dmd
The Journal of the Michigan Dental Association
Dr. Tamar Shrikian shares a personal commentary on overcoming professional burnout by seeking fulfillment outside the clinical setting. Identifying isolation as a key factor in clinician stress, she discusses her transformative experience joining a community chorus. The article introduces the concept of a "third place"—a social space distinct from home and work—as essential for maintaining a healthy identity beyond being a health care provider. Shrikian encourages her colleagues to actively build social connections, whether through faith communities, hobbies, or organized dentistry, to foster mutual support and overall well-being within the profession.
Transforaminal Endoscopic Lumbar Decompression: Defining Its Scope And Limitations, Kai-Uwe Lewandrowski, Álvaro Dowling, Jun Ho Lee, Benedikt W Burkhardt, Óscar L. Alves, Avelino Parajón, Jorge Felippe Ramirez, Nicola Montemurro, Alex R. Vaccaro, Morgan P. Lorio
Transforaminal Endoscopic Lumbar Decompression: Defining Its Scope And Limitations, Kai-Uwe Lewandrowski, Álvaro Dowling, Jun Ho Lee, Benedikt W Burkhardt, Óscar L. Alves, Avelino Parajón, Jorge Felippe Ramirez, Nicola Montemurro, Alex R. Vaccaro, Morgan P. Lorio
Department of Orthopaedic Surgery Faculty Papers
BACKGROUND: Transforaminal endoscopic lumbar decompression (TELD) has emerged as a minimally invasive alternative for managing lumbar stenosis and disc herniations. While the literature consistently reports favorable outcomes, real-world adoption remains variable, with discrepancies often linked to surgeon experience and case complexity.
OBJECTIVE: To evaluate surgeon perspectives on the clinical applicability of TELD across different pathologies and compare these findings with published evidence.
METHODS: An international cross-sectional survey was conducted among spine surgeons. Responses were analyzed using Rasch modeling to assess consensus levels, with agreement categorized as strong, moderate, weak, or disagreement. Differential Item Functioning (DIF) and correlation analyses were applied …
A Word From The Writing Team (July 2026), Pam Walter, Mfa, Laura Deloretta, Phd
A Word From The Writing Team (July 2026), Pam Walter, Mfa, Laura Deloretta, Phd
A Word From the Writing Team (Newsletter)
No abstract provided.
Fostering Inclusion: Supporting Children With Hearing Loss In Social Interactions, Danielle Kaletta, Mary Jan Greer
Fostering Inclusion: Supporting Children With Hearing Loss In Social Interactions, Danielle Kaletta, Mary Jan Greer
Summer 2026 OTD Capstone Symposium
This project provided an open-access online program for caregivers of children with hearing loss to facilitate social engagement. Qualitative methods were used to conduct a needs assessment and identify areas of concern, barriers, and limited resources that affect participation in social activities. Based on the needs assessment, a 6-module website was created and published. Occupational therapy-based evidence, research, interventions, and best practices were compiled and adapted to target identified areas. Participants reported overall favorable feedback, stating an increase in knowledge, confidence, and participation.
Llu Dentistry 2026 Summer Edition, Loma Linda University School Of Dentistry
Llu Dentistry 2026 Summer Edition, Loma Linda University School Of Dentistry
Articulator (Dentistry)
In this issue:
4 | Dean's Message
9 | LLUSD Homecoming 2026: A Celebration of Legacy & Future Growth
19 | Celebrating 48 Years A Tribute to Kathleen Moore Rychman
21 | A Natural Calling: Dr. Yawen Peng, Program Director
22 | A Legacy of Excellence R. David Rynearson, DDS'71, MS'87 honored with the O.B. Vaughan Special Recognition Award
25 | CDA Presents Anaheim
32 | Dental Hygiene Pinning Ceremony
36 | Called to Serve Baccalaureate and the Class of 2026
40 | Commencement
45 | President's Award
46 | Prince Award
54 | Dental Hygiene Student Awards
56 | …
Pragmatic Measures In Aided Language Measurement: Aac Clinical Expert Perspectives, Makayla Hydiea Smith
Pragmatic Measures In Aided Language Measurement: Aac Clinical Expert Perspectives, Makayla Hydiea Smith
Speech and Hearing Sciences ETDs
Purpose: The augmentative and alternative communication (AAC) discipline currently lacks psychometrically sound aided language measures. This thesis is designed to address one step in developing such measures: to begin to establish the clinical feasibility of three pragmatic measures – communicative intent, independence/co-construction, and imitation/non-imitation. Therefore, the objective of this thesis is to identify the useability of these pragmatic measures.
Method: A qualitative approach in the form of a focus group was used to examine the perceptions of SLP practitioners who are experts in AAC. Rapid qualitative analysis (RQA) was used to identify relevant themes and subthemes.
Results: Overall, the themes …
Implementing A Sensory-Informed Protocol For Fall Prevention In A Skilled Nursing Facility, Riley R. Scholberg, Amy Lyons-Brown, Elizabeth Force
Implementing A Sensory-Informed Protocol For Fall Prevention In A Skilled Nursing Facility, Riley R. Scholberg, Amy Lyons-Brown, Elizabeth Force
Summer 2026 OTD Capstone Symposium
This capstone project developed and implemented a sensory-informed admission protocol to support fall prevention at a skilled nursing facility. The development of this protocol aimed to improve the early identification of vision and hearing impairments and integrate sensory considerations into resident care planning and fall prevention. Participants included newly admitted residents and interdisciplinary staff members from rehabilitation, nursing, and administration. Methods included administering the Screening for Severe Dual Sensory Loss (SDSL), reviewing resident characteristics and fall-related indicators, educating staff on sensory-informed care, and developing practical resources to support consistent screening, documentation, and intervention. Expected outcomes included increased staff knowledge, improved …
A Program To Address Anxiety And/Or Add/Adhd In Children With Cerebral Palsy To Improve Social Participation, Victoria Shaw, Mary Jan Greer
A Program To Address Anxiety And/Or Add/Adhd In Children With Cerebral Palsy To Improve Social Participation, Victoria Shaw, Mary Jan Greer
Summer 2026 OTD Capstone Symposium
The purpose of this project was to develop a program for children with cerebral palsy, who experience anxiety and/or ADD/ADHD, that will promote their social participation during play activities. The program lasted for 14 weeks and had two participants, within those 14 weeks, several objectives were accomplished. These objectives include the administration of the needs assessment, implementation of the program modules, pre- and post-interviews with the caregivers and staff, and the finalization of the program. The expected outcome from the program was to determine the effectiveness of the different program modules increasing interactions with peers by decreasing anxiety and improving …
A Hand Therapy Quick Reference Guide: Supporting Level Ii Fieldwork Experiences , Raven I. Gammage, Rebecca Caudrillier, Mary Greer
A Hand Therapy Quick Reference Guide: Supporting Level Ii Fieldwork Experiences , Raven I. Gammage, Rebecca Caudrillier, Mary Greer
Summer 2026 OTD Capstone Symposium
Occupational therapy students often begin Level II hand therapy fieldwork with limited preparation. This capstone project developed an evidence-informed Hand Therapy Quick Reference Guide to support students and clinicians with foundational knowledge and clinical resources. Following implementation, feedback from hand therapists, fieldwork educators, and students indicated the guide was organized, practical, and applicable across clinical settings. The guide has the potential to improve fieldwork preparedness and support successful entry into hand therapy practice.
A Hand Therapy Quick Reference Guide: Supporting Level Ii Fieldwork Experiences, Raven I. Gammage, Rebecca Caudrillier, Mary Greer
A Hand Therapy Quick Reference Guide: Supporting Level Ii Fieldwork Experiences, Raven I. Gammage, Rebecca Caudrillier, Mary Greer
Summer 2026 OTD Capstone Symposium
Occupational therapy students often begin Level II hand therapy fieldwork with limited preparation. This capstone project developed a Hand Therapy Quick Reference Guide to support students and clinicians with foundational knowledge and clinical resources. Evaluative feedback from hand therapists, fieldwork educators, and students indicated the guide was organized, practical, and applicable across clinical settings. The guide has the potential to improve fieldwork preparedness and support success in hand therapy practice.
Inactive Nurses In New Mexico: Insights Into License Lapse And Inactive Reserve Status, Kiyoko Dell Davis
Inactive Nurses In New Mexico: Insights Into License Lapse And Inactive Reserve Status, Kiyoko Dell Davis
Doctor of Nursing Practice Posters and Presentations
Nursing shortages have varied over the decades, yet persist at local, national, and global levels. Nurses report leaving the workforce for many reasons, including professional environment factors resulting from these shortages, further exacerbating a shrinking workforce and population growth. Recent efforts include recruitment and education incentives and implementation of the New Mexico Board of Nursing (NMBON) Inactive Reserve Licensure option, which allows retiring nurses to maintain a reduced-scope nursing license with fewer barriers. Despite these efforts, questions remain: why are nurses in New Mexico leaving the profession and would this licensure category have impacted retention? The purpose of this project …
Inactive Nurses In New Mexico: Insights Into License Lapse And Inactive Reserve Status, Kiyoko Dell Davis
Inactive Nurses In New Mexico: Insights Into License Lapse And Inactive Reserve Status, Kiyoko Dell Davis
Doctor of Nursing Practice Scholarly Projects
Nursing shortages have varied over the decades, yet persist at local, national, and global levels. Nurses report leaving the workforce for many reasons, including professional environment factors resulting from these shortages, further exacerbating a shrinking workforce and population growth. Recent efforts include recruitment and education incentives and implementation of the New Mexico Board of Nursing (NMBON) Inactive Reserve Licensure option, which allows retiring nurses to maintain a reduced-scope nursing license with fewer barriers. Despite these efforts, questions remain: why are nurses in New Mexico leaving the profession and would this licensure category have impacted retention? The purpose of this project …
Improving Continuity Of Care: Evaluating Universal Nursing Handoff Sheets, Elizabeth Ifeloluwa Sanya
Improving Continuity Of Care: Evaluating Universal Nursing Handoff Sheets, Elizabeth Ifeloluwa Sanya
Doctor of Nursing Practice Scholarly Projects
Effective communication during nursing handoffs is essential for safe, patient-centered care, as breakdowns in communication are a leading cause of adverse patient outcomes. At a large academic level I trauma center, inconsistent nursing handoff practices were identified across progressive care units following the COVID-19 pandemic. This variability contributed to incomplete transfer of patient information and was associated with increased patient safety incidents, including delayed wound care, central line dressing lapses, and medication errors involving high-alert therapies. The purpose of this DNP project was to plan, implement, and evaluate the use of standardized nursing handoff sheet and its impact on continuity …
Antibody-Oligonucleotide Conjugates: An Emerging Modality For Precision Rna Therapeutics, Chen-Hsu Yu, Summer Y Y Ha, Zhiqiang An, Kyoji Tsuchikama, Wenbo Li
Antibody-Oligonucleotide Conjugates: An Emerging Modality For Precision Rna Therapeutics, Chen-Hsu Yu, Summer Y Y Ha, Zhiqiang An, Kyoji Tsuchikama, Wenbo Li
The Brown Foundation: Institute of Molecular Medicine
RNA-targeting therapeutics have enormous potential to precisely target disease-causing RNAs, extending beyond the traditional limits of "druggability" for small molecules, antibodies, and protein-targeting cell therapies. However, one crucial limitation is that RNA-targeting drug modalities (such as oligonucleotides) cannot effectively reach diseased tissue or cell types. Antibody-oligonucleotide conjugates (AOCs) emerge as a promising frontier in aiding RNA therapeutics by harnessing antibodies to deliver drug modalities to target specific RNAs in desired tissues or cells. In this Review, we summarize the critical components of AOCs, key considerations for their design and manufacturing, ongoing AOCs in preclinical/clinical development, and disease indications. We discuss …
Transoral Endoscopic Stapled Diverticulotomy For Pediatric Esophageal Diverticulum: A Case Report, Nadeen Alturki, Huma Quraishi, Keith A. Kuenzler
Transoral Endoscopic Stapled Diverticulotomy For Pediatric Esophageal Diverticulum: A Case Report, Nadeen Alturki, Huma Quraishi, Keith A. Kuenzler
Manuscripts, Articles, Book Chapters and Other Papers
Introduction
Pharyngoesophageal diverticula are rare in the pediatric population and are typically managed with open surgical approaches. Minimally invasive surgical (MIS) approaches are well established in adults however, to date, no MIS technique for pediatric esophageal diverticula has been described in the literature.Case presentation
A 12-year-old female presented with neck and chest pain, dysphagia, and difficulty breathing and speaking following ingestion of food from a broken glass jar. Imaging demonstrated a retropharyngeal abscess with a retained foreign body requiring thoracoscopic drainage. The patient subsequently developed a cervical esophageal diverticulum associated with persistent symptoms. She underwent transoral endoscopic stapled diverticulotomy …Factors Associated With Pre-Donation Health-Related Quality-Of-Life Among Pediatric Sibling Hematopoietic Cell Donors: A Donorkids Ql Study., Galen E. Switzer, Jessica G. Bruce, Bronwen E. Shaw, Vidya Kuniyil, James W. Varni, Brandan J. Butler, Connor Erickson, Alisha Mussetter, Allison Neutzling, Hisham Abdel-Azim, Paibel Aguayo-Hiraldo, Eric J. Anderson, Victor M. Aquino, Karlie Boone, Farid Boulad, Joseph H. Chewning, Jessica Cooper, Ann Dahlberg, Christopher C. Dvorak, Jorge Galvez-Silva, Ann E. Haight, Jennifer A. Hoag, Michelle Hudspeth, David Jacobsohn, Kimberly A. Kasow, Carrie L. Kitko, Lakshmanan Krishnamurti, Lisa Madden, Holly K. Miller, Erin Morales, Timothy S. Olson, Anna B. Pawlowska, Vinod K. Prasad, Troy C. Quigg, Andromachi Scaradavou, Niketa C. Shah, Shalini Shenoy, Nancy Terwilliger, Lori Wiener, Gregory A. Yanik, Lolie C. Yu, Michael A. Pulsipher
Factors Associated With Pre-Donation Health-Related Quality-Of-Life Among Pediatric Sibling Hematopoietic Cell Donors: A Donorkids Ql Study., Galen E. Switzer, Jessica G. Bruce, Bronwen E. Shaw, Vidya Kuniyil, James W. Varni, Brandan J. Butler, Connor Erickson, Alisha Mussetter, Allison Neutzling, Hisham Abdel-Azim, Paibel Aguayo-Hiraldo, Eric J. Anderson, Victor M. Aquino, Karlie Boone, Farid Boulad, Joseph H. Chewning, Jessica Cooper, Ann Dahlberg, Christopher C. Dvorak, Jorge Galvez-Silva, Ann E. Haight, Jennifer A. Hoag, Michelle Hudspeth, David Jacobsohn, Kimberly A. Kasow, Carrie L. Kitko, Lakshmanan Krishnamurti, Lisa Madden, Holly K. Miller, Erin Morales, Timothy S. Olson, Anna B. Pawlowska, Vinod K. Prasad, Troy C. Quigg, Andromachi Scaradavou, Niketa C. Shah, Shalini Shenoy, Nancy Terwilliger, Lori Wiener, Gregory A. Yanik, Lolie C. Yu, Michael A. Pulsipher
Manuscripts, Articles, Book Chapters and Other Papers
Due to limited published data assessing pediatric hematopoietic cell donor experiences, we previously conducted one of the largest quantitative investigations of pediatric donor experiences and health-related quality-of-life (HRQoL) at the time (RDSafe). Findings from RDSafe demonstrated that a subset of pediatric HC donors experienced very poor HRQoL; unfortunately, that dataset addressed only a limited number of factors, and key associations explaining this poor HRQoL were not found. In this study, our goal was to address that deficit by describing pre-donation donor HRQoL in detail and identifying factors across five key domains that were associated with donor HRQoL. We conducted a …