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Articles 691 - 720 of 5985
Full-Text Articles in Entire DC Network
Executive Summary: Quality Improvement Initiative Personalized Interdisciplinary Fall Prevention Plan And Fall Rates At An Inpatient Rehabilitation Hospital, Kayla Jackson
Walden Dissertations and Doctoral Studies
Despite ongoing fall prevention strategies, falls continue to be a concern across healthcare organizations. There has been an identified increase in the fall rate at an inpatient rehabilitation facility (IRF) in the southeastern United States. An interprofessional and collaborative approach to fall prevention has been found to lead to a decrease in falls with injury and an increase in the culture of safety. This doctor of nursing practice (DNP) project involved an evaluation of a quality improvement (QI) initiative of a personalized interdisciplinary fall prevention plan at a rehabilitation hospital located in the southeastern region of the United States. The …
Executive Summary: Quality Improvement Initiative Implementing Fixed Water Dispensers In An Inpatient Psychiatric Hospital, Elycia Victoria Hernandez
Executive Summary: Quality Improvement Initiative Implementing Fixed Water Dispensers In An Inpatient Psychiatric Hospital, Elycia Victoria Hernandez
Walden Dissertations and Doctoral Studies
The current hydration system using water pitchers was outdated and inefficient, leading to potential risks of contamination, inconsistent hydration, and increased staff workload in this inpatient psychiatric facility. Psychiatric patients may struggle to access adequate hydration due to cognitive or behavioral limitations. Addressing this gap is essential for improving patient care, enhancing operational efficiency, and ensuring consistent access to clean water. This DNP scholarly project was an evaluation of an interprofessional team-based quality initiative to replace traditional water pitchers with fixed water dispensers in an acute inpatient psychiatric facility. The primary practice-focused question was: Will an interprofessional team reach consensus …
Addressing Practice Effects In Population-Based Studies Of Trends In Late-Life Dementia And Cognitive Impairment, Vicki A Freedman, Mengyao Hu
Addressing Practice Effects In Population-Based Studies Of Trends In Late-Life Dementia And Cognitive Impairment, Vicki A Freedman, Mengyao Hu
Faculty, Staff and Student Publications
No abstract provided.
Integrating Geriatric House Call Practice Into Paramedic Education: A Novel Educational Approach On Attitudes And Acceptance, Phillip D. Magidson, Mariah L. Robertson, Robby May, Mattan Schuchman, Eric Garfinkel, Matthew J. Levy
Integrating Geriatric House Call Practice Into Paramedic Education: A Novel Educational Approach On Attitudes And Acceptance, Phillip D. Magidson, Mariah L. Robertson, Robby May, Mattan Schuchman, Eric Garfinkel, Matthew J. Levy
Journal of Geriatric Emergency Medicine
Objective: This study aimed to assess the feasibility and acceptance of integrating geriatric house call practice clinical exposure into paramedic education and to explore the impact on attitudes towards older adults among paramedic students.
Methods: Paramedic students from a fire department training program participated in a geriatric house call practice in collaboration with an academic health system. Pre- and post-program surveys were conducted to evaluate changes in attitudes towards older adults using the Ageing Semantic Differential (ASD) scale. Patient feedback on paramedic involvement was collected through post-visit surveys.
Results: Six paramedic students completed 25 house call visits over eight weeks. …
Age-Related Decline In Blood-Brain Barrier Function Is More Pronounced In Males Than Females In Parietal And Temporal Regions, Xingfeng Shao, Qinyang Shou, Kimberly Felix, Brandon Ojogho, Xuejuan Jiang, Brian T Gold, Megan M Herting, Eric L Goldwaser, Peter Kochunov, Elliot Hong, Ioannis Pappas, Meredith Braskie, Hosung Kim, Steven Cen, Kay Jann, Danny J J Wang
Age-Related Decline In Blood-Brain Barrier Function Is More Pronounced In Males Than Females In Parietal And Temporal Regions, Xingfeng Shao, Qinyang Shou, Kimberly Felix, Brandon Ojogho, Xuejuan Jiang, Brian T Gold, Megan M Herting, Eric L Goldwaser, Peter Kochunov, Elliot Hong, Ioannis Pappas, Meredith Braskie, Hosung Kim, Steven Cen, Kay Jann, Danny J J Wang
Faculty, Staff and Student Publications
The blood-brain barrier (BBB) plays a pivotal role in protecting the central nervous system (CNS), and shielding it from potential harmful entities. A natural decline of BBB function with aging has been reported in both animal and human studies, which may contribute to cognitive decline and neurodegenerative disorders. Limited data also suggest that being female may be associated with protective effects on BBB function. Here, we investigated age and sex-dependent trajectories of perfusion and BBB water exchange rate (kw) across the lifespan in 186 cognitively normal participants spanning the ages of 8-92 years old, using a non-invasive diffusion-prepared pseudo-continuous arterial …
Disparities In Cognitive Decline Along The Texas-Mexico Border: Insights From The 2021 Brfss, Bianca D. Valenzuela
Disparities In Cognitive Decline Along The Texas-Mexico Border: Insights From The 2021 Brfss, Bianca D. Valenzuela
Health and Kinesiology Theses
The aging global population has brought increased attention to cognitive health and early detection of cognitive decline. Subjective Cognitive Decline (SCD), defined as self-reported memory or thinking problems, is an early marker of neurodegenerative diseases. Despite growing research, gaps remain in understanding how geographic disparities influence SCD prevalence and contributing factors. The Texas-Mexico border region, predominantly Hispanic and facing unique socioeconomic and health care challenges, offers a unique context to explore these influences. The purpose of this study was to examine the prevalence of SCD and related functional limitations in Texas-Mexico border counties versus non-border counties, using 2021 Behavioral Risk …
Dementia Risk Reduction In The African Context: Multi-National Implementation Of Multimodal Strategies To Promote Healthy Brain Aging In Africa (The Africa-Fingers Project), Chinedu Momoh, Rachel Maina, Lukoye Atwoli, Karen Blackmon, Edna Bosire, Gloria Chemutai, Linda Khakali, Sylvia Mbugua, Zul Merali, Olivera Nesic Taylor,, Anthony Ngugi, Cyprian Mostert, Eunice Muthoni, Roselyter Riang’A, Mansoor Saleh, Shahin Sayed, Jasmit Shah
Dementia Risk Reduction In The African Context: Multi-National Implementation Of Multimodal Strategies To Promote Healthy Brain Aging In Africa (The Africa-Fingers Project), Chinedu Momoh, Rachel Maina, Lukoye Atwoli, Karen Blackmon, Edna Bosire, Gloria Chemutai, Linda Khakali, Sylvia Mbugua, Zul Merali, Olivera Nesic Taylor,, Anthony Ngugi, Cyprian Mostert, Eunice Muthoni, Roselyter Riang’A, Mansoor Saleh, Shahin Sayed, Jasmit Shah
Brain and Mind Institute
Dementia prevention in Africa is critically underexplored, despite the continent's high prevalence of modifiable risk factors. With a predominantly young and middle-aged population, Africa presents a prime opportunity to implement evidence-based strategies that could significantly reduce future dementia cases and mitigate its economic impact. The multinational Africa-FINGERS program offers an innovative solution, pioneering culturally sensitive, multidomain interventions tailored to the unique challenges of the region. Leveraging insights from landmark global studies such as Worldwide-FINGERS and Alzheimer's Disease Neuroimaging Initiative, the program employs a multideterminant precision prevention framework, grounded in community based systems dynamics. Africa-FINGERS further integrates cutting-edge state-of-the-art multimodal biomarker …
Iglon5 Frequency In Idiopathic Rem Sleep Behavior Disorder: A Multicenter Study, Ronald Postuma, Jennifer Mcleland, Albert A. Davis, Yo-El S. Ju, Et Al.
Iglon5 Frequency In Idiopathic Rem Sleep Behavior Disorder: A Multicenter Study, Ronald Postuma, Jennifer Mcleland, Albert A. Davis, Yo-El S. Ju, Et Al.
2020-Current year OA Pubs
BACKGROUND AND OBJECTIVES: Idiopathic/isolated REM sleep behavior disorder (iRBD) has been strongly linked to neurodegenerative synucleinopathies such as Parkinson disease, dementia with Lewy bodies, and multiple system atrophy. However, there have been increasing reports of RBD as a presenting feature of serious and treatable autoimmune syndromes, particularly IGLON5. This study's objective was to investigate the frequency of autoantibodies in a large cohort of participants with iRBD.
METHODS: Participants were enrolled in the North American Prodromal Synucleinopathy cohort with polysomnography-confirmed iRBD, free of parkinsonism and dementia. Plasma samples were systematically screened for the autoantibodies IGLON5, DPPX, LGI1, and CASPR2 using plasma …
Genomic Analysis Of Intracranial And Subcortical Brain Volumes Yields Polygenic Scores Accounting For Variation Across Ancestries, Luis M García-Marín, Adrian I Campos, Santiago Diaz-Torres, Jill A Rabinowitz, Zuriel Ceja, Brittany L Mitchell, Katrina L Grasby, Jackson G Thorp, Ingrid Agartz, Saud Alhusaini, David Ames, Philippe Amouyel, Ole A Andreassen, Konstantinos Arfanakis, Alejandro Arias-Vasquez, Nicola J Armstrong, Lavinia Athanasiu, Mark E Bastin, Alexa S Beiser, David A Bennett, Joshua C Bis, Marco P M Boks, Dorret I Boomsma, Henry Brodaty, Rachel M Brouwer, Jan K Buitelaar, Ralph Burkhardt, Wiepke Cahn, Vince D Calhoun, Owen T Carmichael, Mallar Chakravarty, Qiang Chen, Christopher R K Ching, Sven Cichon, Benedicto Crespo-Facorro, Fabrice Crivello, Anders M Dale, George Davey Smith, Eco J C De Geus, Philip L De Jager, Greig I De Zubicaray, Stéphanie Debette, Charles Decarli, Chantal Depondt, Sylvane Desrivières, Srdjan Djurovic, Stefan Ehrlich, Susanne Erk, Thomas Espeseth, Guillén Fernández, Irina Filippi, Simon E Fisher, Debra A Fleischman, Evan Fletcher, Myriam Fornage, Andreas J Forstner, Clyde Francks, Barbara Franke, Tian Ge, Aaron L Goldman, Hans J Grabe, Robert C Green, Oliver Grimm, Nynke A Groenewold, Oliver Gruber, Vilmundur Gudnason, Asta K Håberg, Unn K Haukvik, Andreas Heinz, Derrek P Hibar, Saima Hilal, Jayandra J Himali, Beng-Choon Ho, David F Hoehn, Pieter J Hoekstra, Edith Hofer, Wolfgang Hoffmann, Avram J Holmes, Georg Homuth, Norbert Hosten, M Kamran Ikram, Jonathan C Ipser, Clifford R Jack, Neda Jahanshad, Erik G Jönsson, Rene S Kahn, Ryota Kanai, Marieke Klein, Maria J Knol, Lenore J Launer, Stephen M Lawrie, Stephanie Le Hellard, Phil H Lee, Hervé Lemaître, Shuo Li, David C M Liewald, Honghuang Lin, W T Longstreth, Oscar L Lopez, Michelle Luciano, Pauline Maillard, Andre F Marquand, Nicholas G Martin, Jean-Luc Martinot, Karen A Mather, Venkata S Mattay, Katie L Mcmahon, Patrizia Mecocci, Ingrid Melle, Andreas Meyer-Lindenberg, Nazanin Mirza-Schreiber, Yuri Milaneschi, Thomas H Mosley, Thomas W Mühleisen, Bertram Müller-Myhsok, Susana Muñoz Maniega, Matthias Nauck, Kwangsik Nho, Wiro J Niessen, Markus M Nöthen, Paul A Nyquist, Jaap Oosterlaan, Massimo Pandolfo, Tomas Paus, Zdenka Pausova, Brenda W J H Penninx, G Bruce Pike, Bruce M Psaty, Benno Pütz, Simone Reppermund, Marcella D Rietschel, Shannon L Risacher, Nina Romanczuk-Seiferth, Rafael Romero-Garcia, Gennady V Roshchupkin, Jerome I Rotter, Perminder S Sachdev, Philipp G Sämann, Arvin Saremi, Muralidharan Sargurupremraj, Andrew J Saykin, Lianne Schmaal, Helena Schmidt, Reinhold Schmidt, Peter R Schofield, Markus Scholz, Gunter Schumann, Emanuel Schwarz, Li Shen, Jean Shin, Sanjay M Sisodiya, Albert V Smith, Jordan W Smoller, Hilkka S Soininen, Vidar M Steen, Dan J Stein, Jason L Stein, Sophia I Thomopoulos, Arthur W Toga, Diana Tordesillas-Gutiérrez, Julian N Trollor, Maria C Valdes-Hernandez, Dennis Van T Ent, Hans Van Bokhoven, Dennis Van Der Meer, Nic J A Van Der Wee, Javier Vázquez-Bourgon, Dick J Veltman, Meike W Vernooij, Arno Villringer, Louis N Vinke, Henry Völzke, Henrik Walter, Joanna M Wardlaw, Daniel R Weinberger, Michael W Weiner, Wei Wen, Lars T Westlye, Eric Westman, Tonya White, A Veronica Witte, Christiane Wolf, Jingyun Yang, Marcel P Zwiers, M Arfan Ikram, Sudha Seshadri, Paul M Thompson, Claudia L Satizabal, Sarah E Medland, Miguel E Rentería
Genomic Analysis Of Intracranial And Subcortical Brain Volumes Yields Polygenic Scores Accounting For Variation Across Ancestries, Luis M García-Marín, Adrian I Campos, Santiago Diaz-Torres, Jill A Rabinowitz, Zuriel Ceja, Brittany L Mitchell, Katrina L Grasby, Jackson G Thorp, Ingrid Agartz, Saud Alhusaini, David Ames, Philippe Amouyel, Ole A Andreassen, Konstantinos Arfanakis, Alejandro Arias-Vasquez, Nicola J Armstrong, Lavinia Athanasiu, Mark E Bastin, Alexa S Beiser, David A Bennett, Joshua C Bis, Marco P M Boks, Dorret I Boomsma, Henry Brodaty, Rachel M Brouwer, Jan K Buitelaar, Ralph Burkhardt, Wiepke Cahn, Vince D Calhoun, Owen T Carmichael, Mallar Chakravarty, Qiang Chen, Christopher R K Ching, Sven Cichon, Benedicto Crespo-Facorro, Fabrice Crivello, Anders M Dale, George Davey Smith, Eco J C De Geus, Philip L De Jager, Greig I De Zubicaray, Stéphanie Debette, Charles Decarli, Chantal Depondt, Sylvane Desrivières, Srdjan Djurovic, Stefan Ehrlich, Susanne Erk, Thomas Espeseth, Guillén Fernández, Irina Filippi, Simon E Fisher, Debra A Fleischman, Evan Fletcher, Myriam Fornage, Andreas J Forstner, Clyde Francks, Barbara Franke, Tian Ge, Aaron L Goldman, Hans J Grabe, Robert C Green, Oliver Grimm, Nynke A Groenewold, Oliver Gruber, Vilmundur Gudnason, Asta K Håberg, Unn K Haukvik, Andreas Heinz, Derrek P Hibar, Saima Hilal, Jayandra J Himali, Beng-Choon Ho, David F Hoehn, Pieter J Hoekstra, Edith Hofer, Wolfgang Hoffmann, Avram J Holmes, Georg Homuth, Norbert Hosten, M Kamran Ikram, Jonathan C Ipser, Clifford R Jack, Neda Jahanshad, Erik G Jönsson, Rene S Kahn, Ryota Kanai, Marieke Klein, Maria J Knol, Lenore J Launer, Stephen M Lawrie, Stephanie Le Hellard, Phil H Lee, Hervé Lemaître, Shuo Li, David C M Liewald, Honghuang Lin, W T Longstreth, Oscar L Lopez, Michelle Luciano, Pauline Maillard, Andre F Marquand, Nicholas G Martin, Jean-Luc Martinot, Karen A Mather, Venkata S Mattay, Katie L Mcmahon, Patrizia Mecocci, Ingrid Melle, Andreas Meyer-Lindenberg, Nazanin Mirza-Schreiber, Yuri Milaneschi, Thomas H Mosley, Thomas W Mühleisen, Bertram Müller-Myhsok, Susana Muñoz Maniega, Matthias Nauck, Kwangsik Nho, Wiro J Niessen, Markus M Nöthen, Paul A Nyquist, Jaap Oosterlaan, Massimo Pandolfo, Tomas Paus, Zdenka Pausova, Brenda W J H Penninx, G Bruce Pike, Bruce M Psaty, Benno Pütz, Simone Reppermund, Marcella D Rietschel, Shannon L Risacher, Nina Romanczuk-Seiferth, Rafael Romero-Garcia, Gennady V Roshchupkin, Jerome I Rotter, Perminder S Sachdev, Philipp G Sämann, Arvin Saremi, Muralidharan Sargurupremraj, Andrew J Saykin, Lianne Schmaal, Helena Schmidt, Reinhold Schmidt, Peter R Schofield, Markus Scholz, Gunter Schumann, Emanuel Schwarz, Li Shen, Jean Shin, Sanjay M Sisodiya, Albert V Smith, Jordan W Smoller, Hilkka S Soininen, Vidar M Steen, Dan J Stein, Jason L Stein, Sophia I Thomopoulos, Arthur W Toga, Diana Tordesillas-Gutiérrez, Julian N Trollor, Maria C Valdes-Hernandez, Dennis Van T Ent, Hans Van Bokhoven, Dennis Van Der Meer, Nic J A Van Der Wee, Javier Vázquez-Bourgon, Dick J Veltman, Meike W Vernooij, Arno Villringer, Louis N Vinke, Henry Völzke, Henrik Walter, Joanna M Wardlaw, Daniel R Weinberger, Michael W Weiner, Wei Wen, Lars T Westlye, Eric Westman, Tonya White, A Veronica Witte, Christiane Wolf, Jingyun Yang, Marcel P Zwiers, M Arfan Ikram, Sudha Seshadri, Paul M Thompson, Claudia L Satizabal, Sarah E Medland, Miguel E Rentería
Faculty, Staff and Student Publications
Subcortical brain structures are involved in developmental, psychiatric and neurological disorders. Here we performed genome-wide association studies meta-analyses of intracranial and nine subcortical brain volumes (brainstem, caudate nucleus, putamen, hippocampus, globus pallidus, thalamus, nucleus accumbens, amygdala and the ventral diencephalon) in 74,898 participants of European ancestry. We identified 254 independent loci associated with these brain volumes, explaining up to 35% of phenotypic variance. We observed gene expression in specific neural cell types across differentiation time points, including genes involved in intracellular signaling and brain aging-related processes. Polygenic scores for brain volumes showed predictive ability when applied to individuals of diverse …
Sex Differences In Hypertension And Its Management Throughout Life, Wan-Jin Yeo, Rahul Abraham, Aditya L Surapaneni, Pascal Schlosser, Shoshana H Ballew, Bige Ozkan, Carina M Flaherty, Bing Yu, Joseph V Bonventre, Chirag R Parikh, Paul L Kimmel, Ramachandran S Vasan, Josef Coresh, Morgan E Grams
Sex Differences In Hypertension And Its Management Throughout Life, Wan-Jin Yeo, Rahul Abraham, Aditya L Surapaneni, Pascal Schlosser, Shoshana H Ballew, Bige Ozkan, Carina M Flaherty, Bing Yu, Joseph V Bonventre, Chirag R Parikh, Paul L Kimmel, Ramachandran S Vasan, Josef Coresh, Morgan E Grams
Faculty, Staff and Student Publications
Background: The prevalence of hypertension and uncontrolled hypertension may differ by age and sex.
Methods: We included participants in the Atherosclerosis Risk in Communities study at seven study visits over 33 years (visit 1: 15 636 participants; mean age, 54 years; 55% women), estimating sex differences in prevalence of hypertension (systolic blood pressure ≥130 mm Hg; diastolic blood pressure ≥80 mm Hg; or self-reported antihypertension medication use) and uncontrolled hypertension (systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg) using unadjusted and comorbidity-adjusted models.
Results: The prevalence of hypertension increased with age from 40% (ages, 43-46 …
Association Analysis Of Mitochondrial Dna Heteroplasmic Variants: Methods And Application, Xianbang Sun, Katia Bulekova, Jian Yang, Meng Lai, Achilleas N Pitsillides, Xue Liu, Yuankai Zhang, Xiuqing Guo, Qian Yong, Laura M Raffield, Jerome I Rotter, Stephen S Rich, Goncalo Abecasis, April P Carson, Ramachandran S Vasan, Joshua C Bis, Bruce M Psaty, Eric Boerwinkle, Annette L Fitzpatrick, Claudia L Satizabal, Dan E Arking, Jun Ding, Daniel Levy, Chunyu Liu
Association Analysis Of Mitochondrial Dna Heteroplasmic Variants: Methods And Application, Xianbang Sun, Katia Bulekova, Jian Yang, Meng Lai, Achilleas N Pitsillides, Xue Liu, Yuankai Zhang, Xiuqing Guo, Qian Yong, Laura M Raffield, Jerome I Rotter, Stephen S Rich, Goncalo Abecasis, April P Carson, Ramachandran S Vasan, Joshua C Bis, Bruce M Psaty, Eric Boerwinkle, Annette L Fitzpatrick, Claudia L Satizabal, Dan E Arking, Jun Ding, Daniel Levy, Chunyu Liu
Faculty, Staff and Student Publications
We rigorously assessed a comprehensive association testing framework for heteroplasmy, employing both simulated and real-world data. This framework employed a variant allele fraction (VAF) threshold and harnessed multiple gene-based tests for robust identification and association testing of heteroplasmy. Our simulation studies demonstrated that gene-based tests maintained an appropriate type I error rate at α = 0.001. Notably, when 5 % or more heteroplasmic variants within a target region were linked to an outcome, burden-extension tests (including the adaptive burden test, variable threshold burden test, and z-score weighting burden test) outperformed the sequence kernel association test (SKAT) and the original burden …
Impact Of Diabetes Self-Management Education On Hemoglobin A1c Levels In The Rural Patient Population, Barbara Adomakomensah Sarpong
Impact Of Diabetes Self-Management Education On Hemoglobin A1c Levels In The Rural Patient Population, Barbara Adomakomensah Sarpong
Electronic Theses and Dissertations
The global prevalence of type 2 diabetes is one of the greatest health threats in society, especially in the rural population. Rural healthcare data analysis has proved a need for type 2 diabetes control education. Despite the existence of helpful diabetes control interventions, rural diabetes patients still struggle to maintain healthy behaviors, with about 60% of the patients recording hemoglobin A1c levels above 9. Many suffer severe conditions (e.g., stroke, kidney failure, and heart attacks) because of poor management of the condition. The project examined the impact of diabetes self-management education on hemoglobin A1c levels in the rural patient population. …
Senescence Biomarkers And Trajectories Of Frailty And Physical Function After Kidney Transplantation, Elizabeth C Lorenz, Byron H Smith, Hani M Wadei, Girish Mour, Cassie C Kennedy, Carrie A Schinstock, Walter K Kremers, Andrea L Cheville, Latonya J Hickson, Elizabeth J Atkinson, Thomas A White, Andrew D Rule, Nathan K Lebrasseur
Senescence Biomarkers And Trajectories Of Frailty And Physical Function After Kidney Transplantation, Elizabeth C Lorenz, Byron H Smith, Hani M Wadei, Girish Mour, Cassie C Kennedy, Carrie A Schinstock, Walter K Kremers, Andrea L Cheville, Latonya J Hickson, Elizabeth J Atkinson, Thomas A White, Andrew D Rule, Nathan K Lebrasseur
Faculty, Staff and Students Publications
Cellular senescence is a biological mechanism of aging and age-related diseases. The aim of this study was to examine whether senescence biomarkers are associated with frailty and physical function trajectories in patients undergoing kidney transplantation (KT). We also discussed the relationship between senescence biomarkers and KT function. In this multicenter study, we prospectively assessed plasma levels of senescence biomarkers, frailty as measured by the Physical Frailty Phenotype, and physical function as measured by the Short Physical Performance Battery prior to KT. Frailty, physical function, and KT function were also measured 1 year after KT. Variable associations were assessed using Cox …
Sociodemographic, Lifestyle, And Medical Factors Associated With Calculated Free Testosterone Concentrations In Men: Individual Participant Data Meta-Analyses, Nick Narinx, Ross J Marriott, Kevin Murray, Robert J Adams, Christie M Ballantyne, Douglas C Bauer, Shalender Bhasin, Mary L Biggs, Peggy M Cawthon, David J Couper, Adrian S Dobs, Leon Flicker, Graeme J Hankey, Anke Hannemann, Robin Wilkening, Sean A Martin, Alvin M Matsumoto, Claes Ohlsson, Terence W O'Neill, Eric S Orwoll, Molly M Shores, Antje Steveling, Thomas G Travison, Gary A Wittert, Frederick C W Wu, Leen Antonio, Dirk Vanderschueren, Bu B Yeap
Sociodemographic, Lifestyle, And Medical Factors Associated With Calculated Free Testosterone Concentrations In Men: Individual Participant Data Meta-Analyses, Nick Narinx, Ross J Marriott, Kevin Murray, Robert J Adams, Christie M Ballantyne, Douglas C Bauer, Shalender Bhasin, Mary L Biggs, Peggy M Cawthon, David J Couper, Adrian S Dobs, Leon Flicker, Graeme J Hankey, Anke Hannemann, Robin Wilkening, Sean A Martin, Alvin M Matsumoto, Claes Ohlsson, Terence W O'Neill, Eric S Orwoll, Molly M Shores, Antje Steveling, Thomas G Travison, Gary A Wittert, Frederick C W Wu, Leen Antonio, Dirk Vanderschueren, Bu B Yeap
Faculty, Staff and Students Publications
Objective: Sociodemographic, lifestyle, and medical variables influence total testosterone (T) and sex hormone-binding globulin (SHBG) concentrations. The relationship between these factors and "free" T remains unclear. We examined 21 sociodemographic, lifestyle, and medical predictors influencing calculated free T (cFT) in community-dwelling men across ages.
Design: This is a cross-sectional analysis in 20 631 participants in the Androgens in Men Study.
Methods: Individual participant data (IPD) were provided by 9 cohorts. Total T was determined using mass spectrometry, SHBG using immunoassays, and cFT using the Vermeulen formula. Associations were analyzed using 2-stage random effects IPD meta-analyses.
Results: Cohort median ages ranged …
Practical Strategies For Establishing A Physical Activity Program For Older Aboriginal People - Reflections About Decolonising Practice, Margaret Gidgup, Josephine Umbella, Anne-Marie Hill
Practical Strategies For Establishing A Physical Activity Program For Older Aboriginal People - Reflections About Decolonising Practice, Margaret Gidgup, Josephine Umbella, Anne-Marie Hill
Journal of the Australian Indigenous HealthInfoNet
Background
Physical activity (PA) is a vital component of healthy ageing. However, there are few culturally appropriate PA programs available for older Aboriginal and Torres Strait Islander people. The objectives of this review were to i) assist health professionals to gain understanding about working with older Aboriginal people, ii) provide practical strategies that guide a decolonising approach when delivering PA programs.
Methods
A review of PA program delivery was undertaken by two researchers, one of whom was a Noongar Wadjak woman. The researchers conducted a weekly PA program for older Aboriginal people on Noongar Boodja (Country). The researchers took a …
Social Determinants Of Health And How They Affect A Small Rural Community (Case Study) Eastern Shore Of Maryland, Kristopher S. Durham, Lindsay Gietzen
Social Determinants Of Health And How They Affect A Small Rural Community (Case Study) Eastern Shore Of Maryland, Kristopher S. Durham, Lindsay Gietzen
Pacific Journal of Health
The Eastern Shore of Maryland is rural and is characterized by prevalent poverty, housing instability, lack of access to healthcare, chronic diseases, substance abuse, and issues with transportation to access healthcare services. The same problems exist for the population in Maryland and the United States. Understanding the challenges experienced by rural communities in Maryland is critical to addressing the vulnerable population. This study is an explanatory case study that examines the social determinants of health and how those affect small rural communities on the Eastern Shore of Maryland by examining literature published between 2016 and 2024. The literature reviewed resulted …
Creation And Implementation Of A Nurse Practitioner Student Escape Room, Sara Arn, Msn, Crnp, Agpcnp-Bc
Creation And Implementation Of A Nurse Practitioner Student Escape Room, Sara Arn, Msn, Crnp, Agpcnp-Bc
College of Nursing Posters
Introduction
Educational escape rooms have been gaining popularity in nursing institutions over the past few years. The current literature focuses on the creation, implementation, and benefit of escape rooms for undergraduate nursing students. This poster presentation describes the creation and implementation of an educational escape room targeted to the experiences and skills of advanced practice nursing students enrolled in nurse practitioner programs.
Nurse Graduates’ Experiences With Pain Science – A Qualitative Study, Rachel Bee, Cynthia Goodrich
Nurse Graduates’ Experiences With Pain Science – A Qualitative Study, Rachel Bee, Cynthia Goodrich
Wisdom & Compassion: The LUSON Journal
Background: While the nursing profession has made great strides in pain management over the last 20 years, patients often report being under-assessed and undertreated for pain.
Purpose: The study purpose was to understand the lived experiences of practicing nurses who had completed a baccalaureate-level pain management course during their undergraduate training. The study aims included understanding how pain management skills were implemented in the clinical arena, determining barriers to implementing pain management skills, and identifying opportunities to improve the patient experience regarding pain management.
Design: The researchers implemented a qualitative methodology with a phenomenological design. Data collection consisted of semi-structured …
Bridging Big Data In The Enigma Consortium To Combine Non-Equivalent Cognitive Measures, Eamonn Kennedy, Shashank Vadlamani, Hannah M Lindsey, Pui-Wa Lei, Mary Jo-Pugh, Paul M Thompson, David F Tate, Frank G Hillary, Emily L Dennis, Elisabeth A Wilde, Enigma Clinical Endpoints Working Group Collaborators
Bridging Big Data In The Enigma Consortium To Combine Non-Equivalent Cognitive Measures, Eamonn Kennedy, Shashank Vadlamani, Hannah M Lindsey, Pui-Wa Lei, Mary Jo-Pugh, Paul M Thompson, David F Tate, Frank G Hillary, Emily L Dennis, Elisabeth A Wilde, Enigma Clinical Endpoints Working Group Collaborators
Faculty, Staff and Student Publications
Investigators in neuroscience have turned to Big Data to address replication and reliability issues by increasing sample size. These efforts unveil new questions about how to integrate data across distinct sources and instruments. The goal of this study was to link scores across common auditory verbal learning tasks (AVLTs). This international secondary analysis aggregated multisite raw data for AVLTs across 53 studies totaling 10,505 individuals. Using the ComBat-GAM algorithm, we isolated and removed the component of memory scores associated with site effects while preserving instrumental effects. After adjustment, a continuous item response theory model used multiple memory items of varying …
The Role Of Cancer Rehabilitation In Chemotherapy-Induced Sarcopenia, Tracy L. Moore, Jessica Bertram
The Role Of Cancer Rehabilitation In Chemotherapy-Induced Sarcopenia, Tracy L. Moore, Jessica Bertram
Oncology Rehabilitation in Practice
No abstract provided.
An Integrated Review: Faith Community Nurse Transitional Care Model Health Ministry, Youn Kyeong Cummings
An Integrated Review: Faith Community Nurse Transitional Care Model Health Ministry, Youn Kyeong Cummings
DNP Qualifying Manuscripts
The hospital readmission rate is highest among underserved communities, and providing a continuum of care to these populations can yield a greater reduction in the readmission rate. Church and faith-based clinics often help underserved communities, and equipping them with the transitional care model (TCM) and an Advanced Practice Registered Nurse (APRN) with specialized training as a Faith Community Nurse (FCN) can implement whole-person care, improve the health of the community, and reduce hospital readmission.
California has a 14.5% readmission rate. There is uncertainty surrounding the presence of transitional care departments in California's community hospitals, with some of these facilities offering …
Social Determinants Of Alzheimer’S Disease And Dementia: The Mississippi Landscape, Kenneth R. Butler Jr., Denise Lafferty, Stacee B. Naylor, Kimberly C. Tarver Md
Social Determinants Of Alzheimer’S Disease And Dementia: The Mississippi Landscape, Kenneth R. Butler Jr., Denise Lafferty, Stacee B. Naylor, Kimberly C. Tarver Md
Journal of Public Health in the Deep South
Social determinants of health (SDOH) are those conditions in the environment where people are born, live, learn, work, play, worship, and age that affect a wide range of health, physical and cognitive functions, and quality-of-life outcomes and risks. Numerous social factors are significant contributors to the development and progression of various diseases. Recently, much attention has focused on assessing the impact of social factors on Alzheimer's disease and related dementias (ADRD). The objective of this commentary is to describe and assess the SDOH that have been associated with increased risk of ADRD in the context of the social environment in …
Behavioral Factors Associated With Patients' Non-Attendance: A Retrospective Study In An Outpatient Specialty Clinic At A Women's And Children's Hospital In Singapore, Yue Tang, Houyuan Jiang, Jingui Xie, Zhichao Zheng, Chui Yee Loke, Bee Keow Goh
Behavioral Factors Associated With Patients' Non-Attendance: A Retrospective Study In An Outpatient Specialty Clinic At A Women's And Children's Hospital In Singapore, Yue Tang, Houyuan Jiang, Jingui Xie, Zhichao Zheng, Chui Yee Loke, Bee Keow Goh
Research Collection Lee Kong Chian School Of Business
Background: This study aimed to identify behavioral factors that affect patient attendance in outpatient clinics, especially those related to rescheduling. Methods: A retrospective study was conducted on 20,386 appointment records for 6,252 patients in an outpatient specialty clinic at a women’s and children’s hospital in Singapore over 34 months (January 2012–October 2014). Multivariate logistic regression was used to analyze the influence of independent variables on appointment no-shows. Results: The average no-show rate of the study population was 28.87%. Patient historical behaviors were significantly associated with appointment attendance. In particular, a larger number of previous visits, more historical no-shows, more historical …
Motivating Physical Activity With Fitness Tracking And The Interpersonal Context, Sapphire H. Lin, Sonny Rosenthal, Rich Ling
Motivating Physical Activity With Fitness Tracking And The Interpersonal Context, Sapphire H. Lin, Sonny Rosenthal, Rich Ling
Research Collection College of Integrative Studies
Many societies have aging populations. Getting older people to exercise can help them achieve a higher quality of life. Fitness tracking and social support can buttress that goal. This study tested the effects of fitness tracking and spousal influence on the physical activity of older adults. In a 2 (blinded vs. feedback) × 2 (individual vs. dyad) between-group experiment, 240 participants received a fitness tracker with a visible or blinded display. They participated in the three-month experiment either individually or with their spouses. Participants who received feedback met daily step counts of 7500 and 10,000 more frequently than those without …
Parallel Electrophysiological Abnormalities Due To Covid-19 Infection And To Alzheimer’S Disease And Related Dementia, Yang Jiang, Jennifer Neal, Pradoldej Sompol, Görsev Yener, Xianghong Arakaki, Christopher M. Norris, Francesca R. Farina, Agustin Ibanez, Susanna Lopez, Abdulhakim Al-Ezzi, Voyko Kavcic, Bahar Güntekin, Claudio Babiloni, Mihály Hajós
Parallel Electrophysiological Abnormalities Due To Covid-19 Infection And To Alzheimer’S Disease And Related Dementia, Yang Jiang, Jennifer Neal, Pradoldej Sompol, Görsev Yener, Xianghong Arakaki, Christopher M. Norris, Francesca R. Farina, Agustin Ibanez, Susanna Lopez, Abdulhakim Al-Ezzi, Voyko Kavcic, Bahar Güntekin, Claudio Babiloni, Mihály Hajós
Neurology Faculty Publications
Many coronavirus disease 2019 (COVID-19) positive individuals exhibit abnormal electroencephalographic (EEG) activity reflecting “brain fog” and mild cognitive impairments even months after the acute phase of infection. Resting-state EEG abnormalities include EEG slowing (reduced alpha rhythm; increased slow waves) and epileptiform activity. An expert panel conducted a systematic review to present compelling evidence that cognitive deficits due to COVID-19 and to Alzheimer’s disease and related dementia (ADRD) are driven by overlapping pathologies and neurophysiological abnormalities. EEG abnormalities seen in COVID-19 patients resemble those observed in early stages of neurodegenerative diseases, particularly ADRD. It is proposed that similar EEG abnormalities in …
Statistical Analysis Of Telehealth Use And Pre- And Postpandemic Insurance Coverage In Selected Health Care Specialties In A Large Health Care System In Arkansas: Comparative Cross-Sectional Study, Aysenur Betul Cengil, Sandra Eksioglu, Burak Eksioglu, Hari Eswaran, Corey Hayes, Cari A. Bogulski
Statistical Analysis Of Telehealth Use And Pre- And Postpandemic Insurance Coverage In Selected Health Care Specialties In A Large Health Care System In Arkansas: Comparative Cross-Sectional Study, Aysenur Betul Cengil, Sandra Eksioglu, Burak Eksioglu, Hari Eswaran, Corey Hayes, Cari A. Bogulski
Industrial Engineering Faculty Publications and Presentations
Background:
The COVID-19 pandemic triggered policy changes in 2020 that allowed insurance companies to reimburse telehealth services, leading to increased telehealth use, especially in rural and underserved areas. However, with many emergency rules ending in 2022, patients and health care providers face potential challenges in accessing these services.
Objective:
This study analyzed telehealth use across specialties in Arkansas before and after the pandemic (2017-2022) using data from electronic medical records from the University of Arkansas for Medical Sciences Medical Center. We explored trends in insurance coverage for telehealth visits and developed metrics to compare the performance of telehealth versus in-person …
Negara Hukum Kesejahteraan Di Batas Pantai: Paradoks Perlindungan Negara Terhadap Masyarakat Pesisir Di Tengah Perubahan Iklim, Aji Baskoro
Jurnal Ilmu Kesejahteraan Sosial
Climate change poses significant challenges to vulnerable coastal communities in Indonesia. As a welfare state, the Indonesian government is expected to safeguard these vulnerable groups through policies that promote their welfare and sustainable livelihoods. However, current policies create a paradox. This article explores this paradox: on the one hand, Indonesia adheres to the welfare state principle, which demands that all government actions be grounded in law, ensuring public safety and welfare. On the other hand, the policies focus on exploiting natural resources, exacerbating the vulnerabilities of coastal communities, particularly in the face of climate change. The article employs a normative …
Reframing And Advancing Academic Mentorship To Support New And Early Career Faculty Members, Juanita-Dawne R. Bacsu, Patricia C. Heyn, Steffi Kim, Zahra Rahemi, Monique J. Brown, Darina V. Petrovsky, Justine S. Sefcik, Jodi L. Southerland, Jeremy Holloway, Elyse Couch, Ayse Malatyali, Matthew L. Smith
Reframing And Advancing Academic Mentorship To Support New And Early Career Faculty Members, Juanita-Dawne R. Bacsu, Patricia C. Heyn, Steffi Kim, Zahra Rahemi, Monique J. Brown, Darina V. Petrovsky, Justine S. Sefcik, Jodi L. Southerland, Jeremy Holloway, Elyse Couch, Ayse Malatyali, Matthew L. Smith
Faculty Publications
Mentorship is critical to fostering professional growth and career development in academia. However, academic mentorship is often an informal activity that is overlooked and under researched. There is much ambiguity and uncertainty surrounding mentorship roles and strategies in academia. This paper provides recommendations and strategies to reframe and advance academic mentorship to support new and early career faculty.
Exploring Conversations Between A Practitioner And A Person With Dementia, Kotaro Hara, Rosiana Natalie, Wei Soon Cheong, Jingjing Gu, Qianli Xu
Exploring Conversations Between A Practitioner And A Person With Dementia, Kotaro Hara, Rosiana Natalie, Wei Soon Cheong, Jingjing Gu, Qianli Xu
Research Collection School Of Computing and Information Systems
In social service centers, practitioners engage in conversations with clients with dementia to facilitate their daily activities and provide support when they are distressed. However, the nature of the care demands the practitioner’s active engagement, which becomes difficult to deliver as the number of people who need care expands. Researchers have been investigating the efficacy of developing agents that assume conversational tasks to alleviate this work. To contribute to the future design of agents for caregiving, we collected and analyzed ten conversations between clients with mild dementia and practitioners who provide care. Our analyses of turn-taking dynamics and dialogue acts …
Dna Methylation-Derived Immune Cell Proportions And Cancer Risk In Black Participants, Christopher S Semancik, Naisi Zhao, Devin C Koestler, Eric Boerwinkle, Jan Bressler, Rachel J Buchsbaum, Karl T Kelsey, Elizabeth A Platz, Dominique S Michaud
Dna Methylation-Derived Immune Cell Proportions And Cancer Risk In Black Participants, Christopher S Semancik, Naisi Zhao, Devin C Koestler, Eric Boerwinkle, Jan Bressler, Rachel J Buchsbaum, Karl T Kelsey, Elizabeth A Platz, Dominique S Michaud
Faculty, Staff and Student Publications
Prior cohort studies assessing cancer risk based on immune cell subtype profiles have predominantly focused on White populations. This limitation obscures vital insights into how cancer risk varies across race. Immune cell subtype proportions were estimated using deconvolution based on leukocyte DNA methylation markers from blood samples collected at baseline on participants without cancer in the Atherosclerosis Risk in Communities Study. During a mean of 17.5 years of follow-up, 668 incident cancers were diagnosed in 2,467 Black participants. Cox proportional hazards regression was used to examine immune cell subtype proportions and overall cancer incidence and site-specific incidence (lung, breast, and …