Digital Commons Network^™

Cholesterol Metabolism And Oral Health: An Integrative Review, Raíssa Colherinhas, Carla Guimarães Moutinho, Ana Cristina F Vinha, Carla Alexandra Lopes Andrade De Sousa E Silva

International Arab Journal of Dentistry

Background: This integrative review associated changes in cholesterol metabolism and oral diseases. Conditions such as periodontal disease, tooth loss and oral cancer may be influenced by imbalances in lipid levels through mechanisms involving inflammation, oxidative stress, and immune modulation.

Highlight: This review examined scientific studies published mainly in the last decade. The findings indicate consistent associations between hypercholesterolemia or hyperlipidemia and periodontal disease, diabetes mellitus, hypertension, cardiovascular conditions, peri-implant health, and tooth loss. Hypocholesterolemia was associated with oral squamous cell carcinoma. Periodontal disease was the most frequently investigated oral condition, representing almost half of the included studies.

Conclusion …

Psychological Therapy In The Management Of Temporomandibular Disorders: A Systematic Review, Pragatheeswari R, Kavitha M, Sarumathi T, Niveditha B, Barkavi Panchatcharam, Pavithra D, Samu Fathima A I, Vigneshwaran J

International Arab Journal of Dentistry

Aim: To evaluate the effectiveness of psychological therapy in the management of temperomandibular disorders compared to other treatment modalities.

Methodology: Studies were selected according to PICO criteria, considering the RDC/TMD as a reference, improvement of pain and psychological parameters were the primary outcomes. Data search was mainly carried out through electronic search in several renowned databases: PubMed, Embase, Scopus, Web of Science and Google scholar. The publications collected were published between 2010 and 2024. Randomized clinical trials that compared the efficacy of psychological treatment modality with other conservative treatment modalities were screened and evaluated. A total of 5 …

Stem Cell-Based Therapies In Periodontology And Implant Dentistry: A Systematic Review And Meta-Analysis, Abdullah Saeed, Marycris Padrigo

International Arab Journal of Dentistry

Introduction: Periodontal disease and peri-implantitis remain the leading causes of tooth and implant loss, and conventional regenerative procedures consistently fall short of full structural restoration. Stem cell therapies have emerged as a promising alternative, operating through multi-lineage differentiation, immunomodulation via paracrine signaling, and extracellular vesicle communication. Prior systematic reviews, however, lacked methodological rigor — omitting clustering adjustments, REML/HKSJ estimation, prediction intervals, and publication bias modeling.

Aim: This systematic review and meta-analysis evaluated whether stem cell therapy produces superior clinical and radiographic outcomes compared to cell-free controls in adults with periodontal or peri-implant bone defects.

Methods: Searches across …

Evaluation Of Enamel Demineralization Around Bonded Lingual Retainers Cured Using The Transillumination Technique: An In Vitro Sem Study, Monis Raza, Achint Juneja, Udit Chaudhary, Anju Treesa Jacob, Vikas Thakur, Aayush Sudan

International Arab Journal of Dentistry

Introduction: Polymerization technique may influence enamel demineralization around bonded lingual retainers by affecting adhesive integrity.

Methods: Eighty-four mandibular incisors were randomly allocated to conventional curing (30 s), transillumination (30 s), or combined curing (15 s each). Specimens underwent pH cycling and were evaluated using scanning electron microscopy. Demineralization was scored (0–3), and linear lesion depth was measured. Data were analyzed using Kruskal–Wallis, Bonferroni, and Mann–Whitney tests (p ≤ 0.05).

Results: Combined curing significantly reduced demineralization compared with conventional and transillumination protocols (p < 0.001). Gingival regions showed significantly greater demineralization than occlusal regions across all groups.

Conclusions: Combined curing improved enamel preservation and may be an effective strategy for bonded …

Interdisciplinary, Delphi-Driven Consensus Guidelines On The Use Of Intravenous Ketamine Infusions For Depressive Disorders From The American Society Of Ketamine Physicians, Psychotherapists, And Practitioners (Askp3), David S Mathai, Madeleine Cluck, Amna M Aslam, Erin Amato, Arsalan Azam, Michael Banov, Kathleen A Barrett, Carl J Bonnett, David Feifel, Nicolas Grundmann, H Samuel Ko, Rupert Mcshane, Sandhya Prashad, Tatiana Santini, Lowan H Stewart, Patrick Sullivan, Stefany D Wolfsohn, Jill O Robinson, Amy L Mcguire, L Alison Mcinnes

Center for Medical Ethics and Health Policy Staff Publications

Background: Off-label use of intravenous ketamine (IVK) for depression is a widespread practice with limited regulation in the United States. There is an urgent need for current, evidence-informed treatment guidelines to facilitate patient safety, clinical decision-making, and care quality in real-world contexts.

Methods: The American Society of Ketamine Physicians, Psychotherapists and Practitioners (ASKP3) convened an interdisciplinary working committee tasked with creating guidelines for use of IVK for depression in outpatient settings. Guideline development followed a two-stage process: 1) a hybrid systematic and targeted evidence review and preliminary drafting by the committee, and 2) consensus refinement through a modified Delphi method …

Corrigendum To “Characterizing The Metabolites Of The Tyrosine-Kinase Inhibitor Pexidartinib In Mouse Feces, Urine, Plasma, And Liver” [J. Pharm. Biomed. Anal. 265 (2025) 117034], Xuan Qin, Si Chen, John M Hakenjos, Jian Wang, Lei Guo, Ashish Dogra, Zhaoyong Hu, Kevin R Mackenzie, Feng Li

Faculty, Staff and Students Publications

No abstract provided.

The End Of Unmeasured Exploitation: How A.S.M., C.A.S., And S.I.A. Challenge Digital Attention Capitalism, Delante Clark

Graduate Scholarship and Creative Works

Digital attention capitalism generates value through the capture and monetization of human attention, yet it has historically lacked standardized mechanisms for measuring attention-related harm. This paper argues that the Attention Safeguard Models (A.S.M.), Cognitive Attentional Standards (C.A.S.), and Sociological Impact Assessment (S.I.A.) collectively challenge this system by introducing an integrated framework for classifying, measuring, and evaluating digital attention harm and its societal consequences. C.A.S. provides standardized measurement of digital attention harm, A.S.M. identifies and classifies patterns of attentional disruption and manipulation, and S.I.A. evaluates broader impacts on institutions, communities, civic engagement, education, social cohesion, and inequality. Together, these systems transform …

Impact Of A Head-To-Toe Assessment Simulation On The Self-Efficacy Of First Semester Nursing Students, Martin Dole

Nursing Faculty Publications

The transition into clinical practice presents significant challenges for first-semester nursing students, particularly related to self-efficacy and the ability to perform comprehensive patient assessments. Low self-efficacy may negatively influence clinical judgment, skill performance, and patient safety. The purpose of this Doctor of Nursing Practice project was to examine whether participation in a head-to-toe assessment simulation impacted general self-efficacy among first-semester nursing students. Guided by Bandura’s theory of self-efficacy, a quantitative, quasi-experimental, one-group pretest–posttest design was used to evaluate changes in self-efficacy following a high-fidelity simulation experience. A convenience sample of 42 first-semester Bachelor of Science in Nursing students participated in …

Assessment Of Hind Limb Muscle Activity After Stair-Climbing In A Dog Using 18f-Fdg Pet/Ct: A Case Report, Heesoo Ahn, Seungho Lee, Yoocheol Shin, Byoungho An, Dongwook Kim, Byeong-Teck Kang, Gonhyung Kim

The Thai Journal of Veterinary Medicine

Accurate assessment of functional muscle activation is important for planning rehabilitation exercises in canine patients. Conventional methods, such as electromyography and gait analysis, have limitations in evaluating deep muscles and providing a comprehensive assessment of muscle activity. This case study used ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) to assess hind limb muscle activity in a dog after stair-climbing exercise. A 4-year-old castrated male Beagle underwent 1 h of stair-climbing exercise followed by FDG PET/CT scanning. Increased FDG uptake was observed in multiple hind limb muscles, particularly the gluteus medius and quadratus femoris muscles. The quadratus femoris, a deep …

Environmental Predictors Of County-Level Drowning Rates In Georgia, Jeff Turner

Journal of the Georgia Public Health Association

Background: Recent increases in drowning rates, both nationally and within Georgia, have led to renewed interest in the individual, situational/behavioral, and environmental characteristics that impact drowning. This study examines the association between two environmental characteristics, natural surface water coverage and public pools, on drowning fatalities and drowning-related ER visits by county in Georgia

Methods: We gathered county-level data on drowning fatalities and drowning-related ER visits and the number of public pools from the Georgia DPH, surface water coverage from the US Census Bureau, and demographic measures from the CDC. We conducted a linear regression analysis to identify how …

Analysis And Study Of The Content Of Chloride Salts In Oil, Natalia Evgenievna Sheina, Muborak Akramovna Mirshomilova

Technical science and innovation

The article addresses the critical issue of crude oil quality control, specifically focusing on the determination of chloride salts (sodium, calcium, and magnesium), which exert a destructive impact on processing equipment. The paper provides a detailed analysis of the adverse effects of salts, which lead to severe equipment corrosion, scaling, and a reduced yield of valuable oil fractions. The chemical principles and specific applications of two standardized methods for analyzing aqueous extracts according to GOST 21534-2021 and ASTM D3230 are described: indicator (argentometric and mercurimetric) and potentiometric titration. The experimental section presents the results of a comparative analysis of crude …

Recommendations For Preparticipation Cardiovascular Screening For Athletes In Saudi Arabia: A Consensus Statement From The National Heart Center, Saudi Heart Rhythm Society, And National Center For Sudden Death, Alwaleed Aljohar, Bandar S. Al-Ghamdi, Abdulrahman Y. Sabbagh, Fahad Almehmadi, Fayez Bokhari, Naeem Alshoaibi, Yahya Alhebaishi, Wael Alqarawi

Journal of the Saudi Heart Association

Vigorous sports participation provides substantial physical and psychological benefits but may be accompanied by a small risk of sudden cardiac arrest and death in individuals with previously unrecognized cardiovascular disease. Preparticipation cardiovascular screening aims to identify athletes at increased risk, facilitate appropriate evaluation and management, and promote safe participation in sport. Despite growing international experience, no national recommendations have previously existed for Saudi Arabia. Recognizing the rapid expansion of organized sports participation driven by Saudi Vision 2030, an expert panel convened to develop consensus recommendations for the implementation of a nationwide preparticipation cardiovascular screening program. A comprehensive review of contemporary …

J Mich Dent Assoc Oct. 2026

The Journal of the Michigan Dental Association

The October 2026 issue of the Journal of the Michigan Dental Association highlights advocacy, leadership, clinical practice, and practice management for Michigan dentists. The cover story examines how MDA advocacy led to the passage of Senate Bill 105, prohibiting forced virtual credit card transaction fees. Features include a profile on Dr. Raymond Gist, first Black ADA president; clinical guidance on caries management with Dr. Melissa Seibert; insights from the LEAD leadership program; and surgical mindfulness by Dr. Anish Gupta. Regular departments cover unlicensed employee legalities, supporting caregiver employees, open health insurance enrollment, and MDA organizational updates.

Do Research Day Program 2026, Lincoln Memorial University, Debusk College Of Osteopathic Medicine

DO Research Day

DO Research Day was hosted by the DeBusk College of Osteopathic Medicine at Lincoln Memorial University. This program features abstracts from the LMU-DCOM community.

Core Stability Training And Sports Performance: A Bibliometric Mapping (2000–2025), Mimi Guo, Muhamad Hafiz Bin Ismail, Diyana Z. Abdul Ghani, Qi Liang, Yifei Gao

Baltic Journal of Health and Physical Activity

Background: Core stability training has become an important topic in sports science because of its proposed role in athletic performance enhancement, injury prevention, and neuromuscular control. This study aimed to map the knowledge structure, research trends, and collaboration patterns in this field. Materials and Methods: A bibliometric analysis was conducted using the Web of Science Core Collection. Articles and reviews published between 2000 and 2025 were screened according to predefined eligibility criteria. A total of 559 publications were included and analyzed using Bibliometrix and Biblioshiny. Results: Scientific output increased markedly over time, particularly after 2020. The USA and China were …

From Anatomy To Safe Action: The A2d And Scope-D Frameworks For Teaching Clinical Reasoning And Referral Communication In Physical Therapist Education, Arvie Vitente, Pamela Taylor, Christopher Dela Rosa, Art Lubinski

Philippine Journal of Physical Therapy

Introduction. Physical therapist learners may accurately recall anatomy yet struggle to translate it into testable hypotheses, recognize discordant findings, select proportionate actions, and communicate uncertainty within scope. Existing frameworks address clinical reasoning or structured communication, but limited guidance connects anatomy-based hypothesis testing directly to patient-centered referral communication when findings do not fit. This theory piece pairs Anatomy-to-Decision (A2D) with SCOPE-D to address that curricular gap.

Methods. Integrative conceptual design drew on literature concerning physical therapist clinical reasoning, illness scripts, cognitive load, dual-process reasoning, hypothesis-oriented patient management, safety screening, and communication of diagnostic uncertainty. These foundations were translated into features intended …

Conjunctival Papilloma Across Eras: Comparison Of Historical And Modern Cohorts, Lily C. Farrell, Robert J. Medina, Justin C. Muste, Hemal P. Patel, Sara E. Lally, Ralph C. Eagle C. Eagle, Carol L. Shields, Tatyana Milman

Wills Eye Hospital Papers

Objective: To evaluate and compare epidemiology, clinical and histopathologic features, and outcomes of conjunctival papilloma in historical and modern cohorts. Design: Retrospective comparative cohort study. Participants: Patients with conjunctival papilloma at a tertiary referral center between 2015 and 2024. Methods: A retrospective review of Oncology and Pathology records was conducted to identify all patients with conjunctival papilloma over a 10-year period (2015–2024). Data collected included demographics, HPV vaccination status, clinical tumor characteristics, treatment modalities, outcomes, and histopathologic findings of excised lesions. Patients were stratified by age (≤20 vs.> 20 years). Findings were compared with a historical cohort managed at the …

Effects Of Eight-Week High Interval Training On The Distance Covered During Small-Sided Games Versus League Match In Youth Soccer Players, Dorota Lewandowska, Zbigniew Jastrzebski

Baltic Journal of Health and Physical Activity

Background: The aim of the study was to demonstrate the effectiveness of an 8-week high-intensity interval training (HIIT) program on the distance covered by young soccer players during small-sided games (SSG) and a league match. Materials and Methods: The study involved 39 players aged 17–18 years old, divided into two groups, each performing SSG on a pitch with a surface of 90 m² per player (G-90, n = 19) and 180 m² per player (G-180, n = 20). Players (5 × 5) in both groups completed four games, once a week on Tuesdays. Each game lasted 5 minutes with a …

A Combination Of Hyoscyamine And Theophylline For Treatment Of Sick Sinus Syndrome In A Dog, Uraiwan Saengkieo, Arisara Kiatsilapanan, Suwanakiet Sawangkoon

The Thai Journal of Veterinary Medicine

A-12-year-old female West Highland White Terrier presented with a history of cardiac syncope. Physical examination revealed bradycardia. Sick sinus syndrome (SSS) was diagnosed with electrocardiography and 24-hour Holter monitoring. However, the owner made the decision to receive the pharmacological therapy. Therefore, a combination of hyoscyamine sulfate and theophylline was prescribed. Following two adjustments of drug dosage and frequency within a year, the total number of heartbeats increased from 58,091 to 73,686 beats, and the mean heart rate increased from 44 to 59 bpm. After the treatment, the dog became stable and no syncopal episodes were detected, despite the presence of …

Lc-Hrms Identification And In Silico Anti-Elastase Analysis Of Cynometra Cauliflora Leaf Bioactive Fractions, Winni Nur Auli, Otniel Prima Saputra Purba, Afifah Khoirunisa, Anjar Hermadi Saputro, Syahrizal Nasution

Chimica et Natura Acta

The development of natural cosmetic raw materials as anti-aging agents is one area of research that receives significant attention. Secondary metabolites and extracts from plants have been widely studied and found to possess anti-aging activity. Previous research yielded results showing very strong antioxidant activity of the extract and fractions of namnam leaves. This study aims to analyze the metabolite from the strongest fraction from antioxidant activity and analyze the interaction of flavonoid metabolites with elastase enzymes in silico. Metabolite analysis was performed using LC-HRMS. The molecular docking study was conducted on protein code 5A09 using Autodock Tools 1.4.7. The skin …

Implementation Of A Standardized Protocol To Improve Provider Documentation And Initiation Of Guideline-Concordant Hypertension Follow-Up Within 14 Days In Primary Care, Stella Williams

Doctor of Nursing Practice Projects

Hypertension is a major modifiable risk factor for cardiovascular morbidity and mortality, yet timely follow-up after elevated blood pressure (BP) readings is not consistently documented in primary care. This Doctor of Nursing Practice (DNP) quality improvement project evaluated whether a standardized hypertension screening follow-up protocol improved provider initiation or documentation of guideline-concordant follow-up within 14 days. The faculty-approved PICOT population was primary care providers in a primary care clinic; we used eligible electronic health record (EHR) encounters as the analytic records to observe provider performance. We used a quantitative pre/post design and retrospectively reviewed 30 eligible EHR encounters: 15 pre-implementation …

Collective High-Intensity Physical Load And Team Performance In The Fifa U-20 World Cup Chile: Match-By-Match Analysis Of Finalists, Khalid El Mouahid, Salim Khairi, Paweł Chmura, Amine Arfaoui

Baltic Journal of Health and Physical Activity

Background: This study aimed to compare the physical and technical-tactical performance profiles of the two finalist teams (Argentina and Morocco) at the FIFA U-20 World Cup 2025 and to examine the relationships between individual physical loads and collective match performance. Materials and Methods: An observational comparative design was applied using official FIFA match reports. Seven matches per team were analyzed. Physical variables included total distance, distances covered in speed zones (Z3–Z5), high-speed running, sprint distance, and maximal speed, while technical-tactical variables described offensive, defensive, and collective behaviors. Between-team comparisons and correlation analyses were conducted using appropriate parametric and non-parametric procedures. …

Implementation Of A Six-Month Produce Prescription Program For A Rural Medicaid Population Increased Vegetable Consumption And Reduced Food Security In Washington State, Nicole Stendell Hollis, Tafere Belay, Alyssa Castillo, Lupita Silva, Deborah Guack

All Faculty Scholarship for the College of Education and Professional Studies

Objective

Methods

Bemotrizinol And The Modernization Of Us Sunscreen Regulation, Umayr R. Shaikh, Christopher G. Richter, Leela K. Raj, Afrin Mirza, Harold William Higgins, Jane M. Grant-Kels

SKMC Student Presentations and Publications

No abstract provided.

Early Prediction Of The Breast Cancer Response To Neoadjuvant Chemotherapy Based On Intratumoral Interstitial Fluid Pressure Using 3-D Subharmonic-Aided Pressure Estimation, Sung In Choi, Basak Dogan, Corinne E. Wessner, Jessica H. Porembka, Priscilla Machado, B. Bersu Ozcan, Nisha Unni, Maysa Abu-Khalaf, Kenneth Hoyt, Flemming Forsberg, Kibo Nam

Department of Radiology Faculty Papers

Elevated intratumoral interstitial fluid pressure (IFP) may negatively impact the efficacy of neoadjuvant chemotherapy (NAC). This study aimed to predict the breast cancer response to NAC based on intratumoral IFP using 3D contrast-enhanced ultrasound (CEUS) with subharmonic-aided pressure estimation (SHAPE). This prospective study enrolled breast cancer patients undergoing NAC from two clinical sites. 3D CEUS was performed at 0%, 10%, and 30% of NAC completion using a GE Logiq E9 with Definity. The pressure gradients between the tumor and adjacent normal tissue were estimated by SHAPE, utilizing the inverse linear relationship between the ultrasound contrast agent’s subharmonic signal amplitude and …

Early Hands-On Surgical Exposure: Outcomes Of A Student-Led Surgical Externship Program For Preclinical Students, Meryem C. Guler, Elizabeth Spitz, Jennifer E. Geller, Talar Tatarian, Renee Tholey

Department of Surgery Faculty Papers

Objective: Early surgical exposure may potentially influence medical students' decision to pursue a surgical career. At our urban, academic medical school, senior medical students developed a Surgical Externship Program (SEP) to provide first-years with hands-on OR experience. This program is a structured 1- to 2-week immersive experience in which first-year students scrubbed into operations, participated in rounds, and engaged with surgical teams under resident and attending supervision. This study evaluates the SEP's impact on surgical interest, OR confidence, and clinical exposure.

Setting: Academic tertiary care hospital.

Participants: First-year medical students.

Design: First-year students participated in a 1- or 2-week SEP …

A Word From The Writing Team (October 2026), Pam Walter, Mfa, Laura Deloretta, Phd

A Word From the Writing Team (Newsletter)

No abstract provided.

Sex-Based Disparities In Artificial Intelligence For Cardiovascular Disease: A Scoping Review, Maurgan Lee, Tarek Atasi, Michael Mclellan, Yodit Beru, Jason Booza

Population, Patient, Physician and Professionalism Projects

No abstract provided.

Considering Access And Methodological Rigor In Framing Results Of The Bergen 4 Day Treatment Program For Obsessive-Compulsive Disorder, Eric A Storch, Benjamin J Chang

Faculty, Staff and Students Publications

No abstract provided.

Social Responsiveness As A Mediator In Adapted Cognitive Behavioral Therapy For Autistic Youth With Maladaptive And Interfering Anxiety, Jeffrey J Wood, Eric A Storch, Katherine Sung, Karen S Wood, Philip C Kendall

Faculty, Staff and Students Publications

Numerous adaptations to interventions have been included in cognitive behavioral therapy (CBT) for autistic youth. This study examines the degree to which CBT adapted to the social needs of autistic youth confers significant benefit by promoting social responsiveness. A secondary analysis was conducted on a multisite randomized clinical trial (Wood et al. in JAMA Psychiatry 77:474-483, 2020) comparing adapted CBT with standard-of-practice CBT and treatment-as-usual (TA). Autistic youth (N = 167; aged 7-13) with maladaptive and interfering anxiety participated. The adapted CBT (BIACA) uses a modular format, with an emphasis on supplementing common CBT practice elements (reframing and graded exposure) …