Digital Commons Network^™

Impact Of Forbidden Foodstuffs On The Efficacy Of Homoeopathic Medicines: An In Vitro Evaluation, Girish Gupta, A Srivastava, Naveen Gupta, Gaurang Gupta, Sunil Mishra

Indian Journal of Research in Homoeopathy

Background: In previous screening experiment, out of some homoeopathic medicines in 30 and 200 potencies Mezereum 200 showed maximum inhibition to growth of Candida albicans on comparing the 'Zone of Inhibition' in culture plates treated with homoeopathic medicines keeping standard antifungal Ketoconazole, rectified spirit and distilled water as control by using Disc method. Objective: To observe the impact of various forbidden edible items such as garlic, onion, cardamom, clove, caraway, ginger, fenugreek, black pepper, asafoetida, red chilli, green chilli, turmeric, lemon and camphor on the efficacy of Mezereum 200 in the inhibition of growth of human pathogenic fungus C. albicans. …

Therapeutic Theatre With Adolescents At-Risk Of School Dropout, Dan Summer

Expressive Therapies Dissertations

The aim of this study was to assess the effects of therapeutic theatre, a method of drama therapy, on resilience among adolescents at risk of high school dropout. A mixed method approach was employed to qualitatively examine participant perspectives on resilience and quantitatively measure change in resilience. Participants engaged in weekly after-school drama therapy groups to collaborate on developing themes and a script for a performance to be witnessed by an audience of family and community members. Qualitative and quantitative findings were triangulated and embedded to examine relationships. The Behavioral Assessment System for Children Second Edition (BASC-2) and Resilience Scale …

“I Am Not Deaf”: Art-Based Participatory Action Research With Refugee Women From Burma, Hillary Rubesin

Expressive Therapies Dissertations

There are currently over 65 million displaced people across the world. Refugee women present a unique subset of those displaced. These women often struggle with “triple trauma,” but these complex issues can go unvoiced and unaddressed as the women work to hold their families together in the midst of shifting landscapes and shifting gender roles and cultural norms. The following study demonstrates how the arts can offer refugee women an opportunity to express themselves and process complex issues in effective, creative, accessible, therapeutic, and cross-cultural ways. It details the process and explores the impact of an art-based participatory action research …

Oral Glucose Challenge Impairs Skeletal Muscle Microvascular Blood Flow In Healthy People, Ryan D. Russell, Donghua Hu, Timothy Greenaway, James E. Sharman, Stephen Rattigan, Stephen M. Richards, Michelle A. Keske

Health & Human Performance Faculty Publications

Skeletal muscle microvascular (capillary) blood flow increases in the postprandial state or during insulin infusion due to dilation of precapillary arterioles to augment glucose disposal. This effect occurs independently of changes in large artery function. However, acute hyperglycemia impairs vascular function, causes insulin to vasoconstrict precapillary arterioles, and causes muscle insulin resistance in vivo. We hypothesized that acute hyperglycemia impairs postprandial muscle microvascular perfusion, without disrupting normal large artery hemodynamics, in healthy humans. Fifteen healthy people (5 F/10 M) underwent an oral glucose challenge (OGC, 50 g glucose) and a mixed-meal challenge (MMC) on two separate occasions (randomized, crossover design). …

Regional Microglia Are Transcriptionally Distinct But Similarly Exacerbate Neurodegeneration In A Culture Model Of Parkinson's Disease., Eric Wildon Kostuk, Jingli Cai, Lorraine Iacovitti

Department of Neuroscience Faculty Papers

BACKGROUND: Parkinson's disease (PD) is characterized by selective degeneration of dopaminergic (DA) neurons of the substantia nigra pars compacta (SN) while neighboring ventral tegmental area (VTA) DA neurons are relatively spared. Mechanisms underlying the selective protection of the VTA and susceptibility of the SN are still mostly unknown. Here, we demonstrate the importance of balance between astrocytes and microglia in the susceptibility of SN DA neurons to the PD mimetic toxin 1-methyl-4-phenylpyridinium (MPP

METHODS: Previously established methods were used to isolate astrocytes and microglia from the cortex (CTX), SN, and VTA, as well as embryonic midbrain DA neurons from the …

The Logic Of Sexuation In Deleuze And Lacan, Matthew Lovett

Electronic Theses and Dissertations

In The Logic of Sexuation in Deleuze and Lacan, I argue for an account of sexual difference that responds to a tension in feminist philosophy, namely, the problem of the ontological status of the sexed body. In so doing, I turn to the work of Gilles Deleuze and Jacques Lacan. I argue that, rather than being antithetical, the two can be productively read together, in particular with regard to this very question. Ultimately basing my reading in the Deleuzian passive syntheses and dynamic geneses of Difference and Repetition and The Logic of Sense as well as in Lacan’s twentieth …

The Beta-Catenin/Muc1.Ct Interaction In Pancreatic Cancer, Edwin Wiest

Theses & Dissertations

MUC1 is overexpressed in over 90% of pancreatic cancer cases, and its interaction with beta-catenin promotes progression of the disease. Various in vitro and in vivo methods show that beta-catenin and MUC1 interact by way of the cytoplasmic tail of MUC1 (MUC1.CT). This interaction occurs in the membrane of pancreatic cancer cells but is found to a smaller extent in the nucleus as well. Biophysical methods suggest that MUC1 interacts with beta-catenin through a sequence of amino acids in the tail of MUC1 that sit very near the transmembrane domain of MUC1. In pancreatic ductal adenocarcinoma cells, it appears that …

Fear Of The Future: A Sociological Profile Of Anxiety In College, Lauren Hannah

Renée Crown University Honors Thesis Projects - All

College students are currently experiencing what psychologists and media outlets refer to as an "anxiety epidemic." Undergraduates are self-reporting and seeking counseling for anxiety in record numbers. Fear of the Future: A Profile of Anxiety in College is an exploratory sociology project whose aim is to understand the experience, manifestations, and root causes of anxiety in late Millennial college students. The core research involves a survey of over 400 Syracuse University undergraduates and three interviews with some of Syracuse University's professional counselors. The demographic findings of the survey and the common threads among statements from counselors are synthesized to …

Designing Synthetic Environments To Control Valvular Interstital Cells In Vitro, Kent E. Coombs

Biomedical Sciences ETDs

Aortic valve disease (AVD) is a large contributor to health costs in the United States affecting 2.8% of the population greater than 75 years old. With a growing elderly population due to medical advances, AVD will continue to rise in prevalence over time. Current treatments for AVD are insufficient due to a lack of preventative therapies and the bioprosthetic valves used for surgical replacement have major limitations. Tissue engineered heart valves (TEHVs) present an ideal solution to current AVD needs because of their biocompatibility, capability to integrate with the host’s tissue, and ability to utilize the natural repair mechanisms of …

Dancing, Mindfulness, And Our Emotions: Embracing The Mind, Body, And Sole, Alisha M. Collins

Dissertations, Theses, and Capstone Projects

This capstone project examines dance, as an intervention and mindfulness practice that assists with managing our emotions. There is a need for dance therapy in social institutions such as, healthcare facilities, schools, and community centers. Dance therapy has the potential to reduce negative emotions, create mindfulness, improve self-expression, and promote a healthy well-being. I am proposing that dance therapy is applied as a regular practice in social institutions to develop mindfulness and promote emotional stability.

In this study, I argue that dance therapy can contribute to our well-being long term. In addition to this written thesis, a visual component of …

Homeless And Marginally Housed Veteran Perspectives On Participating In A Photo-Elicitation Research Study, Keri L. Rodriguez, Daniel O. Hedayati, Lauren M. Broyles, Melissa E. Wieland, Michael A. Mitchell, James W. Conley, Shaddy K. Saba, Adam J. Gordon

Patient Experience Journal

Photo-elicitation interviewing (PEI) seems a valuable tool for engaging marginalized populations in research despite documented challenges. Given limited data on acceptability of PEI among homeless and marginally housed Veterans, this evaluation aimed to characterize their research experience. Veterans took photographs about health, health behaviors, and health care which facilitated semi-structured interviews. Their research study experience was assessed via a modified Reactions to Research Participation Questionnaire-Revised (RRPQ-R), along with additional survey and open-ended questions. Of the 20 participants who consented and participated, 16 (80%) completed the exit surveys. Most participants (>88%) indicated favorable experiences and limited drawbacks. Respondents disagreed that …

A Mixed-Methods Study Examining Developmental Milestones And Parental Experiences In Ghana, Kate G. Barlow, Stacey Reynolds

The Open Journal of Occupational Therapy

Background: Ghana currently lacks a systematic method for identifying children with developmental delays, and there do not appear to be any culturally sensitive assessment tools available. The objectives of this mixed-methods research study were to explore normal developmental milestones and parental practices in the Ghanaian population. The study also aimed to identify and describe culturally specific factors that should be accounted for on assessments used in the Ghanaian culture.

Methods: Twenty-eight Ghanaian parents were interviewed and asked to participate in a developmental milestone picture-identification task. Quantitative and qualitative data analyses were performed.

Results: The interviews revealed several cultural factors that …

Perceptions Of Chinese Women Coming To The United States To Give Birth: Birth Tourism, Juanita Childs Jaramillo

Doctoral Projects

Birth experiences and perceptions vary greatly among different cultures. There has been an increase in Chinese women who specifically come to the United States (US) to give birth to their child and return back to their native country after being cleared at the postpartum checkup. This practice is known as birth tourism. The aim of this study is to explore the perceptions of childbirth and postpartum experiences among Chinese birth tourists. Twelve women self-identifying as Chinese, between the ages of twenty-four and thirty-eight, who came to the US to give birth to their child, and who were able to read …

Awareness Of Dentists Regarding Immediate Management Of Dental Avulsion : Knowledge, Attitude, And Practice Study., Kamil Zafar, Rabia Ghafoor, Farhan Raza Khan, Muhammad Hasan Hameed

Section of Dental-Oral Maxillofacial Surgery

OBJECTIVE:
To assess the knowledge of practising dentists regarding immediate management of dental avulsion.

METHODS:
The cross-sectional analytical study was conducted in various dental colleges and teaching hospitals of Karachi, Pakistan, in October-November 2016, and comprised dentists working in academic institutions / departments or as general dental practitioners for at least 1 year. The subjects were asked to fill out a self-administered questionnaire. Questions related to knowledge and practice regarding immediate management of dental avulsion was asked and then responses were categorised as good knowledge, moderate and poor knowledge. SPSS 22 was used for data analysis..
RESULTS:
Of the 282 …

United States Born Mexican Origin Women's Descriptions About Their Eating Patterns, Juanita Teresa Garcia

Dissertations (1934 -)

Problem. Mexican origin (MO) women comprise the largest Hispanic subgroup (nearly two-thirds) of Latinas in the US. This subgroup has high incidences of obesity and associated chronic diseases. Modifiable risk factors for obesity and chronic diseases include unhealthy diets and eating patterns. Efforts to understand eating patterns of Hispanics have focused on primarily first-generation Hispanics. To date, limited research has been conducted to explore underlying factors that contribute to eating patterns of US born MO women living in the US. Method. The purpose of this qualitative exploratory-descriptive study, using a thematic analysis approach, was employed to explore 15 US born …

The Mind-Body Problem; Three Equations And One Solution Represented By Immaterial-Material Data, Ion G. Motofei, David L. Rowland

Journal of Mind and Medical Sciences

Human life occurs within a complex bio-psycho-social milieu, a heterogeneous system that is integrated by multiple bidirectional interrelations existing between the abstract-intangible ideas and physical-chemical support of environment. The mind is thus placed between the abstract ideas/ concepts and neurobiological brain that is further connected to environment. In other words, the mind acts as an interface between the immaterial (abstract/ intangible) data and material (biological) support. The science is unable to conceives and explains an interaction between the immaterial and material domains (to understand nature of the mind), this question generating in literature the mind-body problem. We have published in …

Topical Digitoxigenin For Wound Healing: A Feasibility Study, Xinchi Feng, Cuifen Wang, Yunhui Xu, Joel Turley, Zijian Xie, Sandrine Pierre, Jinsong Hao

Pharmaceutical Science and Research

(1) Background: Cardiotonic steroids have been found to stimulate collagen synthesis and might be potential wound healing therapeutics. The objective of this study was to evaluate the feasibility of digitoxigenin and its topical formulation for wound healing; (2) Methods: In the in vitro study, the human dermal fibroblast cells were treated with digitoxigenin and collagen synthesis was assessed. In the in vivo study, digitoxigenin was applied to excisional full-thickness wounds in rats immediately after wounding and remained for three days, and wound open was evaluated over 10 days. A digitoxigenin formulation for topical administration was prepared, and the in vitro …

Surviving Difference: Endocrine-Disrupting Chemicals, Intergenerational Justice, And The Future Of Human Reproduction, Robyn Lee, Roxanne Mykitiuk

Articles & Book Chapters

Endocrine-disrupting chemicals have been identified as posing risks to reproductive health and may have intergenerational effects. However, responses to the potential harms they pose frequently rely on medicalised understandings of the body and normative gender identities. This article develops an intersectional feminist framework of intergenerational justice in response to the potential risks posed by endocrine-disrupting chemicals. We examine critiques of endocrine disruptors from feminist, critical disability and queer standpoints, and explore issues of race and class in exposures. We argue that responding to the risks posed by endocrine disruptors such as brominated flame retardants (BFRs) and phthalates requires developing a …

Fgf2-Dependent Mesenchyme And Laminin-111 Are Niche Factors In Salivary Gland Organoids, Zeinab F. Hosseini, Deirdre A. Nelson, Nicholas Moskwa, Lauren M. Sfakis, James Castracane, Melinda Larsen

Biological Sciences Faculty Scholarship

Epithelial progenitor cells are dependent upon a complex 3D niche to promote their proliferation and differentiation during development, which can be recapitulated in organoids. The specific requirements of the niche remain unclear for many cell types, including the proacinar cells that give rise to secretory acinar epithelial cells that produce saliva. Here, using ex vivo cultures of E16 primary mouse submandibular salivary gland epithelial cell clusters, we investigated the requirement for mesenchymal cells and other factors in producing salivary organoids in culture. Native E16 salivary mesenchyme, but not NIH3T3 cells or mesenchymal cell conditioned medium, supported robust protein expression of …

Trends Of Parent-Adolescent Drug Talk Styles In Early Adolescence, Youngju Shin, Jonathan Pettigrew, Michelle Miller-Day, Michael L. Hecht, Janice L. Krieger

Communication Faculty Articles and Research

The present study seeks to understand how parents as prevention agents approach substance use prevention messages during the period of early adolescence. Students (N = 410) in a drug prevention trial completed surveys from 7th to 9th grade. Using longitudinal data, a series of latent transition analyses was conducted to identify major trends of parent–adolescent drug talk styles (i.e., never talked, situated direct, ongoing direct, situated indirect, and ongoing indirect) in control and treatment conditions. Findings demonstrate a developmental trend in drug talk styles toward a situated style of talk as youth transitioned from 7th grade to 9th grade. …

Differential Effects Of Parental “Drug Talk” Styles And Family Communication Environments On Adolescent Substance Use, Youngju Shin, Michelle Miller-Day, Michael L. Hecht

Communication Faculty Articles and Research

The current study examines the relationships among adolescent reports of parent–adolescent drug talk styles, family communication environments (e.g., expressiveness, structural traditionalism, and conflict avoidance), and adolescent substance use. ANCOVAs revealed that the 9th grade adolescents (N = 718) engaged in four styles of “drug talks” with parents (e.g., situated direct, ongoing direct, situated indirect, and ongoing indirect style) and these styles differed in their effect on adolescent substance use. Multiple regression analyses showed that expressiveness and structural traditionalism were negatively related to adolescent substance use, whereas conflict avoidance was positively associated with substance use. When controlling for family communication …

Factors Associated With Academic Performance Among Second-Year Undergraduate Occupational Therapy Students, Tore Bonsaksen, Brian J. Ellingham, Tove Carstensen

The Open Journal of Occupational Therapy

Background: Research into occupational therapy education and its outcomes for students is growing. More research is needed to determine the factors of importance for occupational therapy students’ academic outcomes. This study aimed to investigate factors associated with academic performance among second-year undergraduate occupational therapy students in Norway.

Methods: Occupational therapy students (n = 111) from two education programs completed questionnaires asking for sociodemographic, work-related, and education-related information. Hierarchical linear regression analysis was used to examine factors independently associated with the students’ academic performance.

Results: A higher age was associated with better average academic performance among the students, whereas having …

Use Of Religious Observance As A Meaningful Occupation In Occupational Therapy, Kelly Thompson, Bryan M. Gee, Sara Hartje

The Open Journal of Occupational Therapy

Background: Research shows that religious and spiritual beliefs influence a person’s health and quality of life. Studies have found that religious people are healthier and require less access to health services, and that clients want to have their religious and spiritual needs addressed as a part of their plan of care.

Method: This study used a descriptive survey design to explore the attitudes and behaviors of occupational therapists concerning religious observance in clinical practice. The survey yielded 181 responses from a random sampling from members of the American Occupational Therapy Association.

Results: The study found that while …

Occupational Adaptation As A Construct: A Scoping Review Of Literature, Lenin Grajo, Angela Boisselle, Elaina Dalomba

The Open Journal of Occupational Therapy

Background: This study integrates research on practice applications of the construct of occupational adaptation with occupational therapy and occupational science literature.

Method: Using Arksey and O’Malley’s 5-step Scoping Study Framework (2005), we conducted a scoping review of 74 articles from five online databases and literature hand-searching and performed quantitative and thematic analyses.

Results: The Occupational Adaptation model (Schkade & Schultz, 1992; n = 74) and the Model of Human Occupation (Kielhofner, 2008; n = 37) were the most frequently cited literature influences. Occupational adaptation has been defined as a process (n = 49), an outcome (n = …

Dynamic Hydrostatic Pressure Regulates Nucleus Pulposus Phenotypic Expression And Metabolism In A Cell Density-Dependent Manner, B. S. Shah, N. O. Chahine

Journal Articles

© 2018 by ASME. Dynamic hydrostatic pressure (HP) loading can modulate nucleus pulposus (NP) cell metabolism, extracellular matrix (ECM) composition, and induce transformation of notochordal NP cells into mature phenotype. However, the effects of varying cell density and dynamic HP magnitude on NP phenotype and metabolism are unknown. This study examined the effects of physiological magnitudes of HP loading applied to bovine NP cells encapsulated within three-dimensional (3D) alginate beads. Study 1: seeding density (1 M/mL versus 4 M/mL) was evaluated in unloaded and loaded (0.1 MPa, 0.1 Hz) conditions. Study 2: loading magnitude (0, 0.1, and 0.6 MPa) applied …

An Examination Of The Relationships Between Attributional Style, Reappraisal, And Depression Risk In Arab Americans, Khadeja Najjar

ETD Archive

While depression is a cross-cultural phenomenon, much of the literature that examines risk factors and mechanisms for its occurrence is examined from a Western perspective. As cultural background and level of acculturation to the host culture is known to shape the expression of depressive disorders, as well as their risk factors, this study examined whether cultural factors influence the relationship between two cognitive emotion regulation processes and depression symptoms. Specifically, this study examined whether the relationship between internal, stable, and global causal attributions for negative events (negative attributional style) and depression is mediated by one’s tendency to reframe the meaning …

Reduction Of Endothelial Nitric Oxide Increases The Adhesiveness Of Constitutive Endothelial Membrane Icam-1 Through Src-Mediated Phosphorylation, Feng Gao, Brandon P. Lucke-Wold, Xiang Li, Aric F. Logsdon, Li-Chong Xu, Sulei Xu, Kyle B. Lapenna, Huaqi Wang, M.A. Hassan Talukder, Christopher A. Siedlecki, Jason D. Huber, Charles L. Rosen, Pingnian He

Faculty & Staff Scholarship

Nitric oxide (NO) is a known anti-adhesive molecule that prevents platelet aggregation and leukocyte adhesion to endothelial cells (ECs). The mechanism has been attributed to its role in the regulation of adhesion molecules on leukocytes and the adhesive properties of platelets. Our previous study conducted in rat venules found that reduction of EC basal NO synthesis caused EC ICAM-1-mediated firm adhesion of leukocytes within 10–30min. This quick response occurred in the absence of alterations of adhesion molecules on leukocytes and also opposes the classical pattern of ICAM-1-mediated leukocyte adhesion that requires protein synthesis and occurs hours after stimulation. The objective …

Strategies For Recruiting A Sample Of Adults With Type 2 Diabetes From Primary Care Clinics In Rural Appalachia: Incorporating Cultural Competence, Roger Carpenter, Laurie A. Theeke

Faculty & Staff Scholarship

Background: Recruiting research participants from primary care in rural Appalachia is a major challenge and can be influenced by cultural characteristics, making it critically important to incorporate strategies of cultural competence in the overall design of clinical research. Objectives: The purpose of this paper is to describe culturally competent strategies used for recruitment and data collection with a sample of adults with type 2 diabetes from primary care settings in Appalachia.

Design: The Purnell model of cultural competence and relevant literature served as a framework for study design. Four overarching approaches informed the organization of recruitment strategies and development of …

Microarray Analysis Of Human Keratinocytes From Different Anatomic Sites Reveals Site-Specific Immune Signaling And Responses To Human Papillomavirus Type 16 Transfection, M. Israr, D. Rosenthal, L. Frejo-Navarro, J. Devoti, C. Meyers, V. R. Bonagura

Journal Articles

No abstract provided.

Tolle Lege Works Published In 2018, Mcquade Library

Bibliographies

Compiled Tolle Lege bibliography of works published by members of the Merrimack College Community in 2018. Works include journal articles, books, book chapters, conference presentations and posters, and more.