Digital Commons Network^™

The Butler-Tarkington Community Member Views On The Perceived Gentrification, Julio C. Trujillo, Jr., Ethan Daniels

Butler Journal of Undergraduate Research

No abstract provided.

The Comparative Cytotoxicity Of Riddelliine In Primary Mouse, Rat And Chick Hepatocytes, Bryan L. Stegelmeier, William S. Resager, Steven M. Colegate

Poisonous Plant Research (PPR)

Dehydropyrrolizidine alkaloid (DHPA) producing plants commonly poison livestock, wildlife and humans. Poisoning occurs when DHPAs are ingested as feed or food, or when they contaminate medicinal or herbal products. Direct toxicologic comparison of individual DHPAs is essential to estimate their actual health risks. This has been problematic due to varying models and difficulties in DHPA isolation or synthesis. In contrast, the macrocyclic DHPA riddelliine is readily isolated and it has been used as a benchmark to characterize different models of toxicity and carcinogenicity. Following earlier work with immortalized cell lines, the objective of this study was to characterize the effect …

Investigation Of The "Cultural Appropriation" Of Yoga, Olivia Bartholomew

Honors Projects

With our world becoming increasingly globalized and cosmopolitan, practices that were once very traditional and spiritual are much different when they confront Western societies. Many yoga instructors and practitioners around the world are concerned about the issue of cultural appropriation within their practice. The researcher defines cultural appropriation to mean the process of a dominant culture manipulating aspects of a marginalized culture for its benefit. Traditionally, yoga comes from India, but it has become popularized throughout the world in our recent human history. Through interviews with nine yoga instructors, each from different yogic traditions, who teach in a variety of …

The Experiences And Well-Being Of Mexican Immigrant Women Living In Traditionally Non-Latinx Communities In Western North Carolina, Melinda Bogardus

Electronic Theses and Dissertations

North Carolina has, in recent decades, experienced significant growth in its Latinx, and more particularly Mexican immigrant population. As a traditionally non-Latinx state, or a state without a long-standing, large Latinx population, many communities and healthcare and service providers within North Carolina still lack knowledge, resources, and skills needed to serve and support Latinx immigrant populations well. Guided by interpretive description, this qualitative study on Mexican immigrant women in Western North Carolina sought to gain knowledge and understanding of what it is like for them to live in a traditionally non-Latinx region and how immigration has affected their well-being. Asking …

Intersectionality, Access, And Women’S Health: Engaging And Enacting A Feminist Model Of Health Care, Nidhi Chawla

Honors Scholar Theses

“Intersectionality, Access, and Women’s Health: Engaging and Enacting a Feminist Model of Health Care” takes seriously the potential role feminist theory can play in the making of a more accessible and effective model of medical care. In terms of theory and methodology, this thesis draws upon Kimberlė Crenshaw’s influential notion of “intersectionality” as a means of mapping multiple identities and subjectivities; as an additional lens, the thesis accesses Audre Lorde’s insistence that one cannot rely on established systems as the basis for progressive politics. Consistent with the reflexive dynamics of intersectional feminism, and guided by the notion that the personal …

Learning To Leave: Filipino Families And The Making Of The Global Filipino Nurse, Yasmin Y. Ortiga

Research Collection School of Social Sciences

This chapter investigates how this process of reconfiguring the “social” plays out in the context of the Philippines’ labor export system and pervasive culture of emigration. Focusing on the case of Filipino nursing graduates seeking to work overseas, this chapter discusses how the success of the Philippines’ labor-brokering process relies on individuals who can take on the responsibility of transforming themselves, mainly through education and training, into desirable workers for future employers. While the migration literature had largely framed emigration as an individual aspiration and project, this chapter demonstrates how families subsidize the Philippine state’s labor export system by taking …

Pregnane Steroidogenesis Is Altered By Hiv-1 Tat And Morphine: Physiological Allopregnanolone Is Protective Against Neurotoxic And Psychomotor Effects, Jason Paris, Philippe Lière, Sarah Kim, Fakhri Mahdi, Meagen E. Buchanan, Sara R. Nass, Alaa N. Qrareya, Mohammed F. Salahuddin, Antoine Pianos, Neïké Fernandez, Zia Shariat-Madar, Pamela E. Knapp, Michaël Schumacher, Kurt F. Hauser

Faculty and Student Publications

Pregnane steroids, particularly allopregnanolone (AlloP), are neuroprotective in response to central insult. While unexplored in vivo, AlloP may confer protection against the neurological dysfunction associated with human immunodeficiency virus type 1 (HIV-1). The HIV-1 regulatory protein, trans-activator of transcription (Tat), is neurotoxic and its expression in mice increases anxiety-like behavior; an effect that can be ameliorated by progesterone, but not when 5α-reduction is blocked. Given that Tat's neurotoxic effects involve mitochondrial dysfunction and can be worsened with opioid exposure, we hypothesized that Tat and/or combined morphine would perturb steroidogenesis in mice, promoting neuronal death, and that exogenous AlloP would …

Reasons For Facebook Usage: Data From 46 Countries, Marta Kowal, Piotr Sorokowski, Agnieszka Sorokowska, Małgorzata Dobrowolska, Katarzyna Pisanski, Anna Oleszkiewicz, Toivo Aavik, Grace Akello, Charlotte Alm, Rizwana Shaikh

Department of Paediatrics and Child Health

No abstract provided.

2020-04-30 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Lori D. Sloane, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Emma Wolinsky, Fiona Nguyen, Ryen Ormesher, Melissa Cossé, Lauren Tagliaferro Epler, Timothy Campbell, Aly Raboff, Hannah Dowdy-Sue, John Powell, Ariel Hurwitz, Alexandra Yingling, Perez Olewe, Gregory Mertz, Kristine Tollestrup, Orrin Myers, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

NM residential facility deaths. NM case update. NM TriCore testing antibodies. Navajo nation cases. May 10 Navajo peak. Udall funding push. El Paso shopping discouraged. NM budget shortfall. Santa Fe furlough. Ethanol sanitizer safety. LA free testing for all. Michigan protest. NM Batelle N95 decontamination. Hospital revenue decline. Wastewater early detection. German herd immunity. 60-day viral shedding possible. Temporary infected “ark”. Prison release preparedness. Low quality research. Phased long-term care. Suicide prevention. Corticosteroid tradeoffs. Cloth mask guidelines. SARS-CoV-2 assays compared. IgG and viral loads. Better testing reporting. Dubious testing vendors. Promising oral drug. Hydroxychloroquine prophylaxis dosing. Umifenovir ineffective. …

A Proposed Music Therapy Protocol For Trauma-Informed, Culturally Aware Practice With Migrants At The Us-Mexico Border, Mackenzie K. Conner

Expressive Therapies Capstone Theses

This paper reviews current literature surrounding therapeutic work done with the migrant population and considers it through the lens of future music therapy interventions to be done at the United States (US)-Mexico border. The migration process across the US-Mexico border is often filled with danger and treachery, leading to trauma responses, such as depression, anxiety, and post traumatic stress disorder. These traumatic experiences are augmented even further if there is a detention period or separation of families. In work reported by psychotherapists, counselors, and expressive arts therapists, there is often a focus of building empowerment, resilience, and coping skills. Yet …

Inclusion In Religion And Spirituality For Children With Special Needs, Mackinzie C. Weiss

Student Capstone Papers

The proposed vision of this capstone project will focus on using occupational therapy interventions to help a local church be more inclusive to children and families with special needs. This capstone project will partner with a pre-existing special needs program to develop evidence based volunteer training, implement a parent respite program, and introduce a movement based program.

Approaches To Studying: A Cross-Sectional Comparison Of Occupational Therapy Students In Six Education Programs In Norway, Astrid Gramstad, Lene Angell Åsli, Susanne G. Johnson, Trine A. Magne, Tove Carstensen, Gry Mørk, Linda Stigen, Tore Bonsaksen

The Open Journal of Occupational Therapy

Students’ approaches to studying have been associated with their academic performance. Although previous research suggests that the cultural and educational context may influence approaches to studying, few studies have investigated differences in study approaches across education programs. The aim of this study was to examine whether approaches to studying differed among occupational therapy students enrolled in six different educational programs in Norway. From a population of 308 students, 187 first-year occupational therapy students in six educational programs in Norway were recruited. The students provided their sociodemographic information and completed the Approaches and Study Skills Inventory for Students (ASSIST), and group …

Art As Meditation: A Mindful Inquiry Into Educator Well-Being, Rachael Crowder, Jennifer Lock, Evelyn Hickey, Mairi Mcdermott, Marlon Simmons, Katrina Wilson, Rebecca Leong, Noeleen De Silva

The Qualitative Report

Being prepared for the intensity and complexities that educators face in their work means building strategies for managing well-being. This qualitative study explored educators’ conceptualizations about their well-being using an arts-based, community-based participatory research (AB-CBPR) methodology. After a brief mindfulness meditation and contemplation of prompting questions, educators were invited to participate in drawing and writing reflections. The artifacts were coded to determine themes. Themes suggested the importance of human connectedness and interconnection, self care and nurturance, the healing qualities of the natural word, and the recognition that institutions need to provide space and resources to support educator well-being. The mindfulness-based …

Compassion And Suppression In Caregivers: Twin Masks Of Tragedy And Joy Of Caring, Emanuele Maria Merlo, Sean M. Mcnabney, Fabio Frisone, Federica Sicari, Mihai Paunica, Catalina Motofei, Salvatore Settineri

Journal of Mind and Medical Sciences

Background: Compassionate caregiving is a critical skill for workers among the helping professions, but the degree of empathy required by caregivers can place high demands on their mental and emotional resources. While many professionals employ successful coping strategies to mitigate these stressors, others experience compassion fatigue or burnout from emotional exhaustion. The objective of this research was to evaluate the relationships between caregivers’ demographic/career variables, compassion satisfaction, compassion fatigue, and psychodynamic defense mechanisms such as suppression, repressive function, regression in the service of the Ego, and rationalization. Methods: Participants were 250 caregivers with 178 (71,2%) women and 72 men (28,8%) …

The Effects Of Saido Learning On The Cognition Of Patients With Dementia: A Retrospective Study, Stephanie N. Laduke

Honors Projects

SAIDO Learning is a cognitive and social intervention developed by the Kumon Institute in 2004 to slow the progress of symptoms in patients diagnosed with dementia. Today, twenty-three nursing facilities nationwide utilize SAIDO Learning. The data in this retrospective study compare the baseline Mini-Mental State Exam (MMSE) scores to the MMSE scores obtained six months after SAIDO Learning is implemented from patients diagnosed with dementia at Waterford Place in Jenison, Michigan. These scores are reassessed every 6 months as a standard of care. The data was deidentified by the staff of Waterford Place before given to the research team. A …

Examining Prevalence Of Eating Disorder Risk And Body Image Dissatisfaction In Female Adolescent Cheerleaders, Kelsi K. Mariner

Senior Theses

Content: Cheerleading has evolved into a highly competitive and physically demanding sport where athletes must balance academics, intense training, and pressure to maintain expected aesthetic qualities of the sport. These requirements can cause distress which may lead athletes to suffer from eating disorder (ED) risk and body image dissatisfaction (BID). Objective: To examine the prevalence of risk for ED and determine the presence of body image dissatisfaction within adolescent cheerleaders. Design: This study was conducted as a part of a larger concurrent study with Dr. Torres-McGehee and Allison Smith. It is a cross sectional study. Setting: Online survey. Participants: Female …

U.S.-Born Mexican-Origin Women’S Descriptions About Their Eating Patterns, Juanita T. Garcia, Leona Vandevusse

College of Nursing Faculty Research and Publications

Introduction

Mexican origin (MO) women comprise the largest Hispanic subgroup of Latinas in the United States. This subgroup has high incidences of obesity and associated chronic diseases. Modifiable risk factors for these include unhealthy diets and eating patterns. Efforts to understand eating patterns of Hispanics have focused on primarily first-generation Hispanics. The purpose of this study was to explore U.S.-born MO women’s descriptions about eating patterns.

Method

A qualitative exploratory-descriptive study, using a thematic analysis approach, was employed. Fifteen MO women were interviewed. The participants were second to fourth generation and reported higher educational attainment, middle-income socioeconomic brackets, and English …

Flavonoids And Other Polyphenols Act As Epigenetic Modifiers In Breast Cancer., Priyanga Selvakumar, Aja Badgeley, Paige Murphy, Hina Anwar, Urvashi Sharma, Katharine Lawrence, Ashakumary Lakshmikuttyamma

College of Pharmacy Faculty Papers

Breast cancer is a common cancer that occurs due to different epigenetic alterations and genetic mutations. Various epidemiological studies have demonstrated an inverse correlation between breast cancer incidence and flavonoid intake. The anti-cancer action of flavonoids, a class of polyphenolic compounds that are present in plants, as secondary metabolites has been a major topic of research for many years. Our review analysis demonstrates that flavonoids exhibit anti-cancer activity against breast cancer occurring in different ethnic populations. Breast cancer subtype and menopausal status are the key factors in inducing the flavonoid's anti-cancer action in breast cancer. The dose is another key …

A Meta-Synthesis Of The American And The European Standards For The Accreditation Of Counseling Training Programs, Natalia Zapolsky

Dissertations

The purpose of this qualitative study was to explore how the European Standards for the accreditation of counseling training programs compare to CACREP standards and to each other. The differences and commonalities between standards have been defined through a meta-synthesis of integrated findings from a large body of inter-related qualitative studies and reinterpretation of the synthesized data.

This qualitative meta-synthesis research was intended to contribute to the process of counseling globalization by exploring the unique cultural features and aspects of the European and the U.S. accrediting systems for counseling training programs. This research revealed 1) the commonly recognized areas that …

Beauty For Ashes: Reflections On Aesthetic Experience And Suffering, Douglas Gilmour

Verbum Incarnatum: An Academic Journal of Social Justice

In this essay, I examine the relationship between aesthetic experience and suffering, and I specifically explore how and why the former can potentially serve to meliorate the severity of the latter. Of course, that art and beauty can provide a certain measure of comfort and healing to the afflicted is a universally acknowledged truth; however, the reasons why this should be so could be considered an equally universal mystery. “I feel we understand too little about the psychology of loss,” writes Arthur Danto, “to understand why the creation of beauty is so fitting a way of marking it.” By exploring …

Music Therapy As A Treatment For Female Adolescents With Childhood Abuse, Janice M. Dvorkin Psy.D, Acmt, Sierra Belmares

Verbum Incarnatum: An Academic Journal of Social Justice

This article describes the preference to using receptive music therapy as a modality for helping an adolescent who has PTSD from childhood abuses. Adolescence is a difficult period during the life span. The second stage of separation/individuation provides challenges to almost all adolescents. This article contains a description of the adolescent behaviors of someone who is experiencing the consequences of PTSD. Along with an explanation of why receptive music therapy is an effective therapy with this population is a case study.

Suppressing Stat5 Signaling Affects Osteosarcoma Growth And Stemness., Dharmalingam Subramaniam, Pablo Angulo, Sivapriya Ponnurangam, Prasad Dandawate, Prabhu Ramamoorthy, Pugazhendhi Srinivasan, Tomoo Iwakuma, Scott J. Weir, Katherine Chastain, Shrikant Anant

Manuscripts, Articles, Book Chapters and Other Papers

Osteosarcoma (OS) is the most common primary bone tumor that primarily affects children and adolescents. Studies suggested that dysregulation JAK/STAT signaling promotes the development of OS. Cells treated with pimozide, a STAT5 inhibitor suppressed proliferation and colony formation and induced sub G0/G1 cell cycle arrest and apoptosis. There was a reduction in cyclin D1 and CDK2 expression and Rb phosphorylation, and activation of Caspase-3 and PARP cleavage. In addition, pimozide suppressed the formation of 3-dimensional osteospheres and growth of the cells in the Tumor in a Dish lung organoid system. Furthermore, there was a reduction in expression of cancer stem …

Application Of Rigour And Credibility In Qualitative Document Analysis: Lessons Learnt From A Case Study, Leanne M. Wood, Bernadette Sebar, Nerina Vecchio

The Qualitative Report

This paper probes functions and processes of qualitative document analysis (QDA), a method widely used in case study research. It firstly demonstrates the application of a QDA framework to inform a case study of women entrepreneurs in rural Australia; and provides insights into the lessons learnt, including strengths and limitations of QDA. Secondly, the paper provides guidelines for novice researchers seeking to use thematic analysis in a QDA process, arguing for rigour in naming assumptions and explicitness about the procedures employed. The paper contributes to discussion in the literature that positions QDA not only as a convenient tool, but as …

Predictors Of Impending Acute Chest Syndrome In Patients With Sickle Cell Anaemia., Salam Alkindi, Ikhlas Al-Busaidi, Bushra Al-Salami, Samir Raniga, Anil Pathare, Samir K. Ballas

Cardeza Foundation for Hematologic Research

Acute chest syndrome (ACS) is a major complication of sickle cell anaemia (SCA) and a leading cause for hospital admissions and death. We aimed to study the spectrum of clinical and laboratory features of ACS and to assess the predisposing factors and predictors of severity. A retrospective case-control cohort was studied by retrieving patient information from electronic medical records after ethical approval. One hundred adolescents and adults with SCA and hospital admissions for ACS were identified through the discharge summaries, along with 20 additional patients presenting with VOC, but without ACS (controls). Among the patients with ACS, fever (>38.5 …

Expression Of Tryptophan 2,3-Dioxygenase In Metastatic Uveal Melanoma, Mizue Terai, Eric R Londin, Ankit Rochani, Emma Link, Bao Lam, Gagan Kaushal, Alok Bhushan, Marlana Orloff, Takami Sato

Kimmel Cancer Center Faculty Papers

Uveal melanoma (UM) is the most common primary eye malignancy in adults and up to 50% of patients subsequently develop systemic metastasis. Metastatic uveal melanoma (MUM) is highly resistant to immunotherapy. One of the mechanisms for resistance would be the immune-suppressive tumor microenvironment. Here, we have investigated the role of tryptophan 2,3-dioxygenase (TDO) in UM. Both TDO and indoleamine 2,3-dioxygenase (IDO) catalyze tryptophan and produce kynurenine, which could cause inhibition of T cell immune responses. We first studied the expression of TDO on tumor tissue specimens obtained from UM hepatic metastasis. High expression of TDO protein was confirmed in all …

Regulation Of Synaptic Development By Astrocyte Signaling Factors And Their Emerging Roles In Substance Abuse, Christopher D. Walker, W. Chris Risher, Mary-Louise Risher

Biomedical Sciences

Astrocytes have critical functions throughout the central nervous system (CNS) and have emerged as regulators of synaptic development and function. With their highly complex morphologies, they are able to interact with thousands of synapses via peripheral astrocytic processes (PAPs), ensheathing neuronal axons and dendrites to form the tripartite synapse. In this way, astrocytes engage in crosstalk with neurons to mediate a variety of CNS processes including the regulation of extracellular matrix protein signaling, formation and maintenance of the blood-brain barrier (BBB), axon growth and guidance, homeostasis of the synaptic microenvironment, synaptogenesis, and the promotion of synaptic diversity. In this review, …

Suicide And Culture, Mehmet Eskin

BAU Journal - Health and Wellbeing

The rates of suicidal ideation, attempts and mortality present a large intersocietal variation. This variation is usually attributed to the role of culture, but the issue is still poorly understood. How does culture contribute to the intersocietal or cross-cultural variation of suicidal behavior? How culture might be involved in the onset, maintenance and aggravation of suicidal tendencies? In this paper, I will be discussing possible mechanisms of culture for the onset, maintenance and aggravation of suicidal propensities. Specifically, I will be examining the role of religion, individualistic-collectivistic value orientations, self-construal and survival versus self-expression values for their relevance to suicidal …

A National Study Of Patient Safety Culture And Event Reporting – An Individual-Level Analysis Stratified By Staff Group And Work Area And A Hospital-Level Trend Analysis, Sara R. Samuel

Graduate Research Theses & Dissertations

Background: This study examined the association between patient safety culture and adverse event reporting in hospitals across the United States. Despite the known benefits of reporting, underreporting remains a pervasive problem. This study’s aims were to examine the associations between cultural dimensions and reporting, in terms of staff group, work area, and 2-year trends across hospitals.

Methods: This was a secondary analysis of national data from the 2018 Agency for Healthcare Research and Quality (AHRQ) Hospital Survey on Patient Safety Culture (HSOPSC), which included 630 hospitals and 382,834 respondents. Logistic regression, generalized linear mixed model, and multiple linear regression analyses …

Service-Learning As Global Citizenship Education: Acting Locally On Global Challenges And Concerns, Genejane M. Adarlo

Health Sciences Faculty Publications

Service-learning is a method of teaching that is increasingly used in higher education. Studies are few though on how local placements in service-learning can bring about global citizenship and promote social justice. Hence, this study used multi-sited ethnography to examine the teaching-learning process of service-learning to better understand the construction of civic identity and sense of agency among students when this method of teaching was approached within the larger context of social justice. Study participants included students taking part in service-learning efforts for literacy and maternal health from Miriam College and Ateneo de Manila University, respectively. Data were gathered and …

Radiation Actions And Dimensions Of Radiation Safety Among U.S. Radiologic Technologists, Quentin T. Moore

Graduate Research Theses & Dissertations

Background: Radiation safety culture is a fundamental contributor to procedural justification, exam optimization, and dose-limiting practices in medical imaging. Multiple intrapersonal, interpersonal, institutional, community, and policy factors could influence the outcomes of radiation safety culture.

Purpose and Aims: The purpose of the study was to examine the determinants of radiation safety culture among U.S. radiologic technologists. The specific aims were to: 1) develop a survey instrument tailored to radiation actions and dimensions of radiation safety with a sequential use of multiple techniques; 2) examine determinants of radiation safety culture employing McLeroy’s socioecological model; 3) examine relationship between the determinants of …