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Abc Pharmaceutical Company Change Model: Implementing J.P. Kotter's 8-Step And Adkar Change Models For Ethical Alignment, Shelbi B. Chandler, Amalfi Gayosso, Alison Lawton, Ali Holness-Roland Dec 2025

Abc Pharmaceutical Company Change Model: Implementing J.P. Kotter's 8-Step And Adkar Change Models For Ethical Alignment, Shelbi B. Chandler, Amalfi Gayosso, Alison Lawton, Ali Holness-Roland

The Scholarship Without Borders Journal

In this paper, we use the pseudonym ABC Pharmaceuticals (ABC) to refer to the company under examination, GlaxoSmithKline (GSK). ABC Pharmaceutical (ABC) must assess, adapt, and change to ensure regulatory compliance, maintain and attract employees, and remain competitive. ABC has a history of erroneous practices and is at risk internally with employees, and externally with regulators and the public sectors. The authors applied J.P. Kotter’s (1996) 8-step and the ADKAR (Hiatt, 2006) models for change management. J.P. Kotter’s top-down model addresses leadership’s role in creating a compelling vision aligned with its actions, and the ADKAR bottom-up model assesses employees’ readiness …


Best Integrated Writing Fall 2025 - Complete Edition, Wright State University School Of Humanities And Cultural Studies, Tracy Smith, Kristie Mckiernan Dec 2025

Best Integrated Writing Fall 2025 - Complete Edition, Wright State University School Of Humanities And Cultural Studies, Tracy Smith, Kristie Mckiernan

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University.


Prevalence And Factors Associated With Regular Fast-Food Consumption Among Adults In The Uae: A Cross-Sectional Study, Ala Al Rajabi, Rafiq Hijazi, Lynne Alexandra Kennedy Dec 2025

Prevalence And Factors Associated With Regular Fast-Food Consumption Among Adults In The Uae: A Cross-Sectional Study, Ala Al Rajabi, Rafiq Hijazi, Lynne Alexandra Kennedy

All Works

Objectives: To assess the prevalence and identify sociodemographic predictors of regular fast-food consumption (R-FFC) among United Arab Emirates (UAE) adults to inform public health nutrition responses to growing diet-related ill health in the region. Design: This is a descriptive cross-sectional study using purposive, convenience sampling. Data were collected using an online survey adapted from two validated surveys and distributed via social media platforms. R-FFC was defined as visiting a fast-food restaurant to eat ≥ 2 times/week. Pearson’s χ 2 tests and multiple binary logistic regression models were used to investigate prevalence and predictors of R-FFC. All statistical significance was considered …


Patient-Derived Ovarian Cancer Models Provide Insight Into Cancer Cell-Intrinsic And Immune Cell-Dependent Effects On Therapeutic Response, Parisa Nikeghbal Dec 2025

Patient-Derived Ovarian Cancer Models Provide Insight Into Cancer Cell-Intrinsic And Immune Cell-Dependent Effects On Therapeutic Response, Parisa Nikeghbal

Biomedical Sciences ETDs

Ovarian cancer is the most lethal gynecologic malignancy, largely due to late diagnosis and resistance to chemotherapy. This dissertation applies patient-derived organoids (PDOs), xenograft-derived organoids (PDXOs), and humanized xenografts (huPDX) to investigate therapeutic responses and immune interactions. Organoids were shown to retain critical features of the original malignancy. Across platinum-sensitive, -resistant, and -refractory cases, both PDOs and PDXOs exhibited drug sensitivities that aligned with patients’ clinical classifications. Building on this foundation, a drug screen revealed novel strategies. Auranofin restored platinum sensitivity in Notch3-active models, afatinib broadly reduced viability, and adavosertib–gemcitabine and sorafenib–topotecan combinations produced synergy. Extending this work, immune interactions …


Moltkia Coerulea Extracts Alleviate Caspase-3 Activity Via Reducing Oxidative Stress In Lps-Induced Neurotoxicity In Bv-2 Cells, Asli Can Ağca, Derya Altay, Hüdaverdi̇ Kul, Asli F. Ceylan, Betül Sever Yilmaz Dec 2025

Moltkia Coerulea Extracts Alleviate Caspase-3 Activity Via Reducing Oxidative Stress In Lps-Induced Neurotoxicity In Bv-2 Cells, Asli Can Ağca, Derya Altay, Hüdaverdi̇ Kul, Asli F. Ceylan, Betül Sever Yilmaz

Turkish Journal of Medical Sciences

Background/aim: Moltkia coerulea, a medicinal plant traditionally used for its neuroprotective properties, contains diverse phenolic compounds. However, its mechanisms of action in neuroinflammation remain unclear. We hypothesized that extracts of M. coerulea may protect microglial cells from lipopolysaccharide (LPS)-induced oxidative stress and apoptosis by modulating reactive oxygen species (ROS) and caspase-3 activity.

Materials and methods: Aqueous and methanol extracts (5–50 μg/mL) were tested in BV-2 microglial cells. Cell viability was assessed by MTT assay, while ROS generation and caspase-3 activity were measured using fluorescence-based kits. The effective concentration (10 μg/mL) was selected for mechanistic assays based on viability data and …


The Reception Of Neurodiversity Represented Within Netflix’S Wednesday, Anna Stevens Dec 2025

The Reception Of Neurodiversity Represented Within Netflix’S Wednesday, Anna Stevens

Graduate Theses & Dissertations

This paper explores how neurodiversity is represented through popular media - particularly Netflix's show Wednesday - and aims to discuss the effects this representation could have in regards to how it's received by the public, as well as those who are neurodiverse.


Disruption Of The Placenta–Brain Axis In Transgenic Mice Lacking Serotonin Transporter (Sert) In Trophoblast Cells, David T. Ellenberger, Zhen Lyu, Rosalind T. B. Herrington, Jessica A. Kinkade, Gustavo W. Leone, Ji Ying Sze, Nathan J. Bivens, R. Frank Baker, R. Michael Roberts, Trupti Joshi, Cheryl S. Rosenfeld Dec 2025

Disruption Of The Placenta–Brain Axis In Transgenic Mice Lacking Serotonin Transporter (Sert) In Trophoblast Cells, David T. Ellenberger, Zhen Lyu, Rosalind T. B. Herrington, Jessica A. Kinkade, Gustavo W. Leone, Ji Ying Sze, Nathan J. Bivens, R. Frank Baker, R. Michael Roberts, Trupti Joshi, Cheryl S. Rosenfeld

Biomedical Sciences

Serotonin reuptake inhibitors (SSRIs) are commonly prescribed to pregnant women experiencing depression. Such drugs, however, might adversely affect placenta and fetal brain development. Parietal trophoblast giant cells (pTGCs) in the mouse placenta are postulated to internalize maternal serotonin (5-HT) via transport through SERT, encoded by Slc6a4, and to provide the initial source of 5-HT to the emerging brain via the placental–brain axis. Genetic deletion of Slc6a4 in pTGCs has been hypothesized to impact placental and fetal brain development. A transgenic mouse line with high-affinity SERT, encoded by Slc6a4, was selectively deleted by pairing mice with Cre recombinase linked …


A Faith-Based Approach To Mental Health Challenges, Patrick Leblanc Dec 2025

A Faith-Based Approach To Mental Health Challenges, Patrick Leblanc

Doctor of Ministry Theses and Dissertations

ABSTRACT

This project sheds light on mental health issues within the Black community and the need for faith communities to intentionally address mental health issues in communities of color. Black men are oppressed by an interplay of cultural, historical, societal, and economic factors that impact their well-being. Racial discrimination and oppression are non-medical drivers exacerbating mental health disorders among Black men. The influences of culture and faith fabricate barriers to help-seeking behavior, and mistaken perceptions of masculinity cause many men to suffer in silence. To begin erasing derogatory perceptions of mental health disorders, faith communities need to increase mental health …


Whipple Disease Initial Presentation As Supraclavicular Lymphadenopathy In A Patient With Rheumatoid Arthritis: A Diagnostic Challenge, Sara E Amin, Swati Gite, Audrey Wanger, Violeta Chavez, Jacob Armstrong, Beenu Thakral, Patricia Navarro, Jennifer Makhoul, Amer Wahed, Navneet Narula, Karan Saluja Dec 2025

Whipple Disease Initial Presentation As Supraclavicular Lymphadenopathy In A Patient With Rheumatoid Arthritis: A Diagnostic Challenge, Sara E Amin, Swati Gite, Audrey Wanger, Violeta Chavez, Jacob Armstrong, Beenu Thakral, Patricia Navarro, Jennifer Makhoul, Amer Wahed, Navneet Narula, Karan Saluja

Faculty, Staff and Student Publications

Whipple disease is a rare systemic disease caused by Tropheryma whipplei. It can present with a wide range of nonspecific symptoms that might overlap with underlying medical conditions, posing a diagnostic challenge. We present a 61-year-old man with a past medical history of rheumatoid arthritis and chronic inflammatory demyelinating polyneuropathy, who presented with persistent leukocytosis and supraclavicular lymphadenopathy. A positron emission tomography scan revealed hypermetabolic activity in the supraclavicular, abdominal, and pelvic lymph nodes along with a myocardial hypermetabolic lesion, concerning a lymphoproliferative disorder versus sarcoidosis. A supraclavicular lymph node excisional biopsy revealed complete architectural effacement by a diffuse foamy …


Improved Model For Neurodegeneration In C. Elegans, Jean-Pierre Arditi Dec 2025

Improved Model For Neurodegeneration In C. Elegans, Jean-Pierre Arditi

Graduate Theses and Dissertations (2019 - present)

During Alzheimer's disease (AD), insoluble amyloid beta (AP) peptides accumulate to form extracellular aggregates (plaques). The direct cause of neuronal dysfunction observed in AD has been broadly investigated. The amyloid hypothesis states that AP plaques are neurotoxic, but recent studies support the AP oligomer hypothesis, which states that intracellular AP (iAP) is neurotoxic. To test this hypothesis, I used CRISPR-Cas9 gene editing to generate two transgenic Caenorhabditis elegans (C. elegans) strains. I generated a strain (RSLl 11) using the rab-3 promoter to co-express GFP in neurons, which showed no gross behavioral changes but had a 50% reduced egglaying rate. RSLl …


The Potential Co-Occurrence Of Perfectionism, Food Insecurity, And Gpa With Orthorexia Nervosa Risk, Samantha Kay Gould Nov 2025

The Potential Co-Occurrence Of Perfectionism, Food Insecurity, And Gpa With Orthorexia Nervosa Risk, Samantha Kay Gould

Master's Theses

There are indeterminate risk, prevalence, and correlation data on orthorexia nervosa (ON) as shown by current literature on disordered eating (Rodgers et al., 2021). As a roughly defined disordered eating pattern, ON may be better understood after identifying associations among other attributes in a college student sample (Abdullah et al., 2020; Mavrandrea & Gonidakis, 2023; Parra-Fernández, 2019; Rogowska et al., 2021). A cooccurrence and influence of perfectionism, food insecurity, and grade point average (GPA) with ON risk was hypothesized since current literature suggests college students exhibit each of these characteristics independently (Abdullah et al., 2020; Ambwani et al., 2019; Caferoglu …


Aging And The Screen: Toxic Commodification Of The Female Body In The Substance (2024), Damlasu Uyug Sengun, Tuncer Mert Aydın, Zeynep Ozdamar Ertekin Nov 2025

Aging And The Screen: Toxic Commodification Of The Female Body In The Substance (2024), Damlasu Uyug Sengun, Tuncer Mert Aydın, Zeynep Ozdamar Ertekin

Markets, Globalization & Development Review

Representations of the aging female body have increased in media, but their presence is still shaped by social norms and market-driven ideals. On the contrary, The Substance (2024), an absurd, postmodern body horror, provides us a provocative critique of contemporary society’s obsession with youth and beauty and the way our culture defines and commodifies aging, especially in relation to women’s bodies and identities. Our review of The Substance incorporates consumer culture theory with Julia Kristeva’s concept of the abject (1982), Laura Mulvey’s theory of the male gaze (1975), and Barbara Creed’s notion of the monstrous-feminine, (1993) to explore the toxic …


In-Silico Assessment Of Aortic Valve Function And Mechanics Under Hypertension, Jason A. Shar, Philippe Sucosky Nov 2025

In-Silico Assessment Of Aortic Valve Function And Mechanics Under Hypertension, Jason A. Shar, Philippe Sucosky

Faculty Articles

Introduction: Calcific aortic valve disease (CAVD) is the most common heart valve disorder. While hypertension is a major risk factor, the mechanisms by which elevated blood pressure contributes to calcification are largely unknown. Given the established sensitivity of aortic valve (AV) tissue to mechanical cues, hypertension may subject AV leaflets to a stress state conducive to CAVD. To address this hypothesis, the objective of this study was to compare AV function and mechanics under normotensive (NTN, 120/ 80 mmHg), pre-hypertensive (preHTN, 125/80 mmHg) and hypertensive (HTN, 130/90 mmHg) conditions using fluid-structure interaction modeling.

Methods: AV flow and leaflet dynamics were …


Prenatal Metabolomics Analysis And Fetal Congenital Anomalies And Genetic Conditions: A Review Of Current Literature, Sarah Araji, Onur Turkoglu, Mohamad Ali Maktabi, Tracy Ashby, Ignatia B Van Den Veyver Nov 2025

Prenatal Metabolomics Analysis And Fetal Congenital Anomalies And Genetic Conditions: A Review Of Current Literature, Sarah Araji, Onur Turkoglu, Mohamad Ali Maktabi, Tracy Ashby, Ignatia B Van Den Veyver

Library Staff Publications

Fetal congenital anomalies and genetic disorders complicate 3%-5% of pregnancies and can have a significant impact on pregnancy outcomes. Precise and individualized prenatal diagnosis is crucial for effective counseling and management. The identification of new biomarkers holds promise for enhancing prenatal screening, diagnosis, and prognostic counseling in affected pregnancies. Recently, metabolomics has emerged as a potential adjunct in the interpretation of genetic variants identified through genome-wide sequencing for rare genetic conditions. To assess the potential of metabolomic profiling as a functional assay capable of providing deeper insights into the pathological processes and genetic findings associated with prenatal congenital anomalies, we …


Myeov Is A Novel Marker Of Differentiated Corneal Epithelium, Yoshiko Fukuda, Chao Zhang, Bruce R. Ksander, Vickie Y. Jo, Christine G. Lian, George F. Murphy, Markus H. Frank, Natasha Y. Frank, Yuzuru Sasamoto Nov 2025

Myeov Is A Novel Marker Of Differentiated Corneal Epithelium, Yoshiko Fukuda, Chao Zhang, Bruce R. Ksander, Vickie Y. Jo, Christine G. Lian, George F. Murphy, Markus H. Frank, Natasha Y. Frank, Yuzuru Sasamoto

Research outputs 2022 to 2026

Purpose. Myeloma overexpressed gene (MYEOV) was initially identified as a gene amplified in several malignancies and was found to promote cell proliferation and metastasis. Our previous comparative RNA sequencing and epigenetic analyses revealed high MYEOV levels in differentiated corneal epithelial cells and showed that TET2 epigenetically regulated MYEOV expression. In the current study, we aimed to further characterize the expression and regulation of MYEOV in the human ocular surface. Methods. MYEOV expression was examined by immunostaining of the human corneas and by analysis of the publicly available single-cell RNA sequencing data. Gene knockdown (KD) of MYEOV and the regulators of …


Diversity In Aquatics:4th Special Issue, Tiffany M. Quash Ph.D., Angela K. Beale-Tawfeeq, Steven N. Waller Ph.D. Oct 2025

Diversity In Aquatics:4th Special Issue, Tiffany M. Quash Ph.D., Angela K. Beale-Tawfeeq, Steven N. Waller Ph.D.

International Journal of Aquatic Research and Education

The theme of this special issue is “Building a Community of Champions.” The purpose of this theme is to highlight and promote a civic engagement perspective that engages, advocates, and supports communities of Black, Indigenous, People of Color (BIPOC) in addressing the national, regional, and local evolving health-related issue of drowning. Aquatic Settings have been a pivotal focal point of social justice, water safety, and public health, not only in the past but also in our present day (Beale-Tawfeeq, Quash, et al, 2023 and Waller and Bemiller, 2023). Diversity In Aquatics (DIA) strives to positively impact the field of aquatics …


Adopting Stuart Hall’S “Race, The Floating Signifier” As A Conceptual Framework Within Aquatic Research And Education, Kurt J. Cordice Oct 2025

Adopting Stuart Hall’S “Race, The Floating Signifier” As A Conceptual Framework Within Aquatic Research And Education, Kurt J. Cordice

International Journal of Aquatic Research and Education

During his 1997 lecture at Goldsmiths College in London, Stuart Hall, renowned for his contributions to sociology and cultural studies, offered his argument that the concept of race functions as a Floating Signifier. In this essay, Stuart Hall’s Race, the Floating Signifier is presented as a strong conceptual framework to support more accurate and effective positioning of race as an important consideration within aquatic research and education. Evidence from a range of disciplines, including historical research, is presented to establish both the importance and challenge of race within aquatic research and education. This evidence is also used to demonstrate …


Phosphorylation At Serine 214 Correlates With Tau Seeding Activity In An Age-Dependent Manner In Two Mouse Models For Tauopathies And Is Required For Tau Transsynaptic Propagation, Pablo Martinez, Nur Jury-Garfe, Henika Patel, Yanwen You, Abigail Perkins, Yingjian You, Audrey Lee-Gosselin, Ruben Vidal, Cristian A Lasagna-Reeves Oct 2025

Phosphorylation At Serine 214 Correlates With Tau Seeding Activity In An Age-Dependent Manner In Two Mouse Models For Tauopathies And Is Required For Tau Transsynaptic Propagation, Pablo Martinez, Nur Jury-Garfe, Henika Patel, Yanwen You, Abigail Perkins, Yingjian You, Audrey Lee-Gosselin, Ruben Vidal, Cristian A Lasagna-Reeves

Faculty, Staff and Students Publications

Background

Tau aggregation and propagation are hallmark features of Alzheimer's disease and related tauopathies. The molecular identity and post-translational modifications that contribute to tau seeding activity remain incompletely understood.

Objective

To characterize the temporal dynamics of tau seeding activity and identify specific phosphorylated tau species associated with tau propagation in vivo.

Methods

We profiled tau seeding activity using a FRET-based biosensor cell line and correlated it with the abundance of phospho- and conformational tau species in two transgenic mouse models of tauopathy (P301S-1N4R and P301S-0N4R). Immunohistochemistry and subcellular fractionation were used to examine the spatial distribution of tau species. Functional …


I’M Here Whether I Like It Or Not: A Focused Ethnographic Description Of Transition Into Residential Aged Care, Stacey Scott, Annette Raynor, Julie Dare, Jennifer Grieve, Leesa Costello Oct 2025

I’M Here Whether I Like It Or Not: A Focused Ethnographic Description Of Transition Into Residential Aged Care, Stacey Scott, Annette Raynor, Julie Dare, Jennifer Grieve, Leesa Costello

Research outputs 2022 to 2026

Transition into residential aged care (RAC) is a challenging process, often characterised by vulnerability, fear, and isolation. This study aimed to provide a contextualised description of transition within a care-facility in Australia to deepen our understanding of this major life event. A focused ethnography was conducted, which included formal interviews with residents during their first 6 months of living in RAC. The findings provide an account of the participants’ views on acceptance, highlight the challenges of loss, and showcase the coping practices new residents used. This paper provides a type of report card for the sector, which reveals that there …


Physical Activity, Screen Time, Dietary Habits, And Health Outcomes Among Children And Adolescents In The Middle East And North Africa Region: A Narrative Review, Shaikha Eisa Alnaqbi, Rahab Sohail, Hadia M. Radwan, Maysm N. Mohamad, Falak Zeb, Haydar Hasan, Mona Hashim, Tareq Osaili, Sharifa Alblooshi, Ayesha S. Al Dhaheri, Lily Stojanovska, Leila Cheikh Ismail Sep 2025

Physical Activity, Screen Time, Dietary Habits, And Health Outcomes Among Children And Adolescents In The Middle East And North Africa Region: A Narrative Review, Shaikha Eisa Alnaqbi, Rahab Sohail, Hadia M. Radwan, Maysm N. Mohamad, Falak Zeb, Haydar Hasan, Mona Hashim, Tareq Osaili, Sharifa Alblooshi, Ayesha S. Al Dhaheri, Lily Stojanovska, Leila Cheikh Ismail

All Works

Background/objectives: Fat mass and obesity associated (FTO) gene and anthropometric measurements might be associated with breast cancer (BC) risk. This study aimed to assess the interactions between single nucleotide polymorphism (SNP) rs9939609 of the FTO gene, anthropometric indices, and BC risk among pre- and post-menopause women with overweight/obesity in Pakistan. Methods: This retrospective case–control study conducted on a convenience sample of 200 women divided into two groups: a case group comprised of 100 women diagnosed with BC, and control group comprised of 100 (age and menopausal status matched healthy women). Physical activity was assessed using validated questionnaire. Data on body …


Prenatal Metabolomics Analysis And Fetal Congenital Anomalies And Genetic Conditions: A Review Of Current Literature, Sarah Araji, Onur Turkoglu, Mohamad Ali Maktabi, Tracy Ashby, Ignatia B Van Den Veyver Sep 2025

Prenatal Metabolomics Analysis And Fetal Congenital Anomalies And Genetic Conditions: A Review Of Current Literature, Sarah Araji, Onur Turkoglu, Mohamad Ali Maktabi, Tracy Ashby, Ignatia B Van Den Veyver

Library Staff Publications

Fetal congenital anomalies and genetic disorders complicate 3%-5% of pregnancies and can have a significant impact on pregnancy outcomes. Precise and individualized prenatal diagnosis is crucial for effective counseling and management. The identification of new biomarkers holds promise for enhancing prenatal screening, diagnosis, and prognostic counseling in affected pregnancies. Recently, metabolomics has emerged as a potential adjunct in the interpretation of genetic variants identified through genome-wide sequencing for rare genetic conditions. To assess the potential of metabolomic profiling as a functional assay capable of providing deeper insights into the pathological processes and genetic findings associated with prenatal congenital anomalies, we …


33 Unresolved Questions In Nanoscience And Nanotechnology, Chad A Mirkin, Sarah Hurst Petrosko, Natalie Artzi, Koray Aydin, Austin Biaggne, C Jeffrey Brinker, Katherine E Bujold, Y Charles Cao, Rachel R Chan, Chaojian Chen, Peng-Cheng Chen, Xiaodong Chen, Olivier J G L Chevalier, Chung Hang Jonathan Choi, Richard M Crooks, Vinayak P Dravid, Jingshan S Du, Sasha B Ebrahimi, Hongyou Fan, Omar K Farha, C Adrian Figg, Tanner D Fink, Connor M Forsyth, Harald Fuchs, Franz M Geiger, Nathan C Gianneschi, Kyle J Gibson, David S Ginger, Sishi Guo, Justin S Hanes, Liangliang Hao, Jin Huang, Bryan M Hunter, Fengwei Huo, Jeongmin Hwang, Rongchao Jin, Shana O Kelley, Thomas J Kempa, Youngeun Kim, Sergej Kudruk, Sneha Kumari, Kaitlin M Landy, Ki-Bum Lee, Noel J Leon, Jun Li, Yuanwei Li, Zhiwei Li, Bin Liu, Guoliang Liu, Xiaogang Liu, Luis M Liz-Marzán, Jochen H Lorch, Taokun Luo, Robert J Macfarlane, Jill E Millstone, Milan Mrksich, Catherine J Murphy, Rajesh R Naik, Andre E Nel, Christopher Oetheimer, Jenny K Hedlund Orbeck, So-Jung Park, Benjamin E Partridge, Nicholas A Peppas, Michelle L Personick, Arindam Raj, Namrata Ramani, Michael B Ross, Stacey Barnaby Ross, Edward H Sargent, Tanushri Sengupta, George C Schatz, Dwight S Seferos, Tamar Seideman, Soyoung Eileen Seo, Bo Shen, Wooyoung Shim, Donghoon Shin, Ulrich Simon, Andrew J Sinegra, Peter T Smith, Alexander M Spokoyny, Peter J Stang, Alexander H Stegh, J Fraser Stoddart, Dayne F Swearer, Weihong Tan, Michelle H Teplensky, C Shad Thaxton, David R Walt, Mary X Wang, Zhe Wang, Wei David Wei, Paul S Weiss, Peter H Winegar, Younan Xia, Yi Xie, Xiaoyang Xu, Peidong Yang, Yiming Yang, Zihao Ye, Kuk Ro Yoon, Cuizheng Zhang, Hua Zhang, Ke Zhang, Liangfang Zhang, Xiaoyu Zhang, Ye Zhang, Zijian Zheng, Wenjie Zhou, Shengshuang Zhu, Wei Zhu Sep 2025

33 Unresolved Questions In Nanoscience And Nanotechnology, Chad A Mirkin, Sarah Hurst Petrosko, Natalie Artzi, Koray Aydin, Austin Biaggne, C Jeffrey Brinker, Katherine E Bujold, Y Charles Cao, Rachel R Chan, Chaojian Chen, Peng-Cheng Chen, Xiaodong Chen, Olivier J G L Chevalier, Chung Hang Jonathan Choi, Richard M Crooks, Vinayak P Dravid, Jingshan S Du, Sasha B Ebrahimi, Hongyou Fan, Omar K Farha, C Adrian Figg, Tanner D Fink, Connor M Forsyth, Harald Fuchs, Franz M Geiger, Nathan C Gianneschi, Kyle J Gibson, David S Ginger, Sishi Guo, Justin S Hanes, Liangliang Hao, Jin Huang, Bryan M Hunter, Fengwei Huo, Jeongmin Hwang, Rongchao Jin, Shana O Kelley, Thomas J Kempa, Youngeun Kim, Sergej Kudruk, Sneha Kumari, Kaitlin M Landy, Ki-Bum Lee, Noel J Leon, Jun Li, Yuanwei Li, Zhiwei Li, Bin Liu, Guoliang Liu, Xiaogang Liu, Luis M Liz-Marzán, Jochen H Lorch, Taokun Luo, Robert J Macfarlane, Jill E Millstone, Milan Mrksich, Catherine J Murphy, Rajesh R Naik, Andre E Nel, Christopher Oetheimer, Jenny K Hedlund Orbeck, So-Jung Park, Benjamin E Partridge, Nicholas A Peppas, Michelle L Personick, Arindam Raj, Namrata Ramani, Michael B Ross, Stacey Barnaby Ross, Edward H Sargent, Tanushri Sengupta, George C Schatz, Dwight S Seferos, Tamar Seideman, Soyoung Eileen Seo, Bo Shen, Wooyoung Shim, Donghoon Shin, Ulrich Simon, Andrew J Sinegra, Peter T Smith, Alexander M Spokoyny, Peter J Stang, Alexander H Stegh, J Fraser Stoddart, Dayne F Swearer, Weihong Tan, Michelle H Teplensky, C Shad Thaxton, David R Walt, Mary X Wang, Zhe Wang, Wei David Wei, Paul S Weiss, Peter H Winegar, Younan Xia, Yi Xie, Xiaoyang Xu, Peidong Yang, Yiming Yang, Zihao Ye, Kuk Ro Yoon, Cuizheng Zhang, Hua Zhang, Ke Zhang, Liangfang Zhang, Xiaoyu Zhang, Ye Zhang, Zijian Zheng, Wenjie Zhou, Shengshuang Zhu, Wei Zhu

Faculty, Staff and Student Publications

Significant advances in science and engineering often emerge at the intersections of disciplines. Nanoscience and nanotechnology are inherently interdisciplinary, uniting researchers from chemistry, physics, biology, medicine, materials science, and engineering. This convergence has fostered novel ways of thinking and enabled the development of materials, tools, and technologies that have transformed both basic and applied research, as well as how we address critical societal challenges. In this Nano Focus, we pose and explore 33 questions whose answers could profoundly impact fields such as energy, electronics, the environment, optics, and medicine. These questions highlight the need for deeper foundational understanding, improved tools …


How Medical Mistrust Serves As A Barrier To Mental Health Treatment In The African American Community, Nicholas Young Sep 2025

How Medical Mistrust Serves As A Barrier To Mental Health Treatment In The African American Community, Nicholas Young

Journal of Social, Behavioral, and Health Sciences

Throughout history, research has depicted the notion that African Americans do not make use of mental health treatment, even when their mental health status may deem it clinically necessary. One of the most prevalent deterrents to African Americans seeking treatment is the mistrust of the medical system. In the African American community, medical mistrust has a longstanding history that stems from the discrimination, racism, lack of representation in the field, and medical mistreatment that African Americans received as test subjects by the medical community over time. Various instances, throughout history, of African Americans being unjustly treated— for the sake of …


A High-Salt Diet Modulates Renal Afferent Nerve Activity; Potential Role Of The Endothelin System, Jiaxi Shen Sep 2025

A High-Salt Diet Modulates Renal Afferent Nerve Activity; Potential Role Of The Endothelin System, Jiaxi Shen

All ETDs from UAB

Hypertension is a prevalent disease around the world. Increased blood pressure leads to a higher risk of stroke and coronary heart disease. Diet, lifestyle, and gene regulation are potential causative factors, and salt-sensitive hypertension is one common types of hypertension. In response to a high-salt diet, blood pressure may elevate with increasing risks of cardiovascular disease (CVD). Endothelin-1, which binds to endothelin A (ETA) and B (ETB) receptors, is strongly involved in controlling the blood vessels and sensory nerve signaling pathway between the kidney and the central nervous system during high salt dietary challenge. The function of the ETB receptor …


Nursing Students’ Sociodemographic Characteristics And Consumer Preferences’ Prediction Level Of Perceived Food Literacy, Sinan Duru Aug 2025

Nursing Students’ Sociodemographic Characteristics And Consumer Preferences’ Prediction Level Of Perceived Food Literacy, Sinan Duru

Makara Journal of Health Research

Background: Food literacy, which is a critical competency for nursing students, plays a pivotal role in promoting evidence-based nutrition behaviors and contributes effectively to public health. This study aimed to determine the level of perceived food literacy among nursing students.

Methods: This cross-sectional study involved 488 nursing students from two universities in the south of Turkey. The research data were collected face to face via the Personal Information Form, the Consumer Preferences Form, and Self Perceived Food Literacy. The data was analyzed using the Independent Sample t Test, One Way ANOVA, and multiple linear regression.

Results: The …


Can Coffee Combat Fatty Liver? A Review Of Emerging Evidence, Mohamed E. Abd El-Hack, Muhammad Arif, Vincenzo Tufarelli, Ayman A. Swelum Aug 2025

Can Coffee Combat Fatty Liver? A Review Of Emerging Evidence, Mohamed E. Abd El-Hack, Muhammad Arif, Vincenzo Tufarelli, Ayman A. Swelum

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

NAFLD (Non-alcoholic fatty liver disease) is an increasingly spread metabolic status characterized by increasing fat accumulation in the liver, obesity closely associated with it, sedentary habits and insulin resistance. Since there is currently no recognized pharmaceutical treatment, lifestyle changes continue to be the mainstay of treatment. Coffee, a globally consumed beverage rich in bioactive and useful compounds like caffeine, cafestol, kahweol, and chlorogenic acids, has emerged as a potential hepatoprotective agent. Evidence from epidemiological experiments, animal studies, and human trials suggests that regular coffee drinking may help decrease hepatic fat levels, improve antioxidant defenses, prevent inflammatory pathways, and prevent or …


Excitotoxic Neuronal Death Requires Superoxide Entry Into Neurons Through Volume-Regulated Anion Channels, Kate Harris, Seok Joon Won, Gokhan Uruk, Nguyen Mai, Devran Ogut, Yonghui Zhao, Litao Xie, Paul Baxter, Katharina Everaerts, Rajan Sah, Raymond A Swanson Aug 2025

Excitotoxic Neuronal Death Requires Superoxide Entry Into Neurons Through Volume-Regulated Anion Channels, Kate Harris, Seok Joon Won, Gokhan Uruk, Nguyen Mai, Devran Ogut, Yonghui Zhao, Litao Xie, Paul Baxter, Katharina Everaerts, Rajan Sah, Raymond A Swanson

2020-Current year OA Pubs

Neuronal death in stroke and other conditions stems in part from stimulation of


Exploration Of Counselors’ Epistemology: Epistemic Style Perspectives In Helping Relationships, Muty Rachmadiny Utami, Nissa Aulia Belistiana Utami, Nandang Budiman Aug 2025

Exploration Of Counselors’ Epistemology: Epistemic Style Perspectives In Helping Relationships, Muty Rachmadiny Utami, Nissa Aulia Belistiana Utami, Nandang Budiman

Jurnal Kajian Bimbingan dan Konseling

Epistemological studies provide important insights into how counselors build their knowledge related to the helping relationship through epistemic styles. This study aims to describe the epistemology of the helping relationship in counseling. A qualitative approach with a case study design was used to explore the experiences of guidance and counseling teachers and students as research participants. Data were collected through the analysis of counseling documents and semi-structured interviews with guidance and counseling teachers as well as five counselee participants. The study results discuss the epistemology of the helping relationship of counselors in seven themes: sources of counselor knowledge, the process …


Intergenerational Family Dynamics Among Caregivers And Children’S Social-Emotional Development In China, Weiman Xu Aug 2025

Intergenerational Family Dynamics Among Caregivers And Children’S Social-Emotional Development In China, Weiman Xu

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The early years of a child’s life are pivotal for social-emotional development. While extensive research has explored the role of family settings in fostering children's social-emotional development (Bornstein, 2005), the impact of grandparental involvement, particularly the caregiving dynamics between generations, remains less well understood. This study aims to fill this gap by examining two critical aspects of intergenerational dynamics among caregivers (i.e. parent-grandparent coparenting and parent-grandparent relationship quality) and their associations with children’s social-emotional development (i.e. social skills and problem behaviors). Two specific aims were delineated: 1) examine the unique contribution of parent-grandparent coparenting, especially the power and authority domain …


Cross-Cultural Comparison Of Nomophobia, Netlessphobia And Anxiety Among Nursing Students In Iran And Türkiye: A Mediation Analysis, Mohsen S. Ardakani, Abdolrahim Asadollahi, Sevil Ç. Özbay, Yalçın Kanbay, Maryam Bakhtiar Aug 2025

Cross-Cultural Comparison Of Nomophobia, Netlessphobia And Anxiety Among Nursing Students In Iran And Türkiye: A Mediation Analysis, Mohsen S. Ardakani, Abdolrahim Asadollahi, Sevil Ç. Özbay, Yalçın Kanbay, Maryam Bakhtiar

Sultan Qaboos University Medical Journal

Objectives: In the digital era, excessive reliance on smartphones and internet access has led to emerging psychological concerns, including nomophobia (fear of being without a mobile phone) and netlessphobia (fear of being without internet), which are increasingly linked to anxiety among students. This study aimed to compare the prevalence and psychological impact of these phobias among nursing students in Iran and Türkiye. Methods: This cross-sectional study was included nursing students; participants completed validated questionnaires assessing nomophobia, netlessphobia and anxiety. Data were collected from June to July 2024 via paper-based and electronic surveys. Statistical analyses included independent t-tests, multiple regression and …