Digital Commons Network^™

Development Of 6-Week Tier 2 Intervention Tracks Within An Elementary Mtss Framework, Maxwell Lyle

Capstone Projects

The Multi-Tiered System of Supports (MTSS) is designed to provide levels of support with differing intensity that align with student needs. Tier 1 is universal instruction provided to all students in the classroom. Students who do not demonstrate adequate progress may receive Tier 2 interventions, which are primarily small-group and, when appropriate, individual interventions that are skill-specific, time-bound (6–8 weeks), and include progress monitoring. Students who do not respond to Tier 2 may require Tier 3 supports, which are intensive, individualized interventions. Many school systems lack consistent, structured Tier 2 supports, particularly in Occupational Therapy-related skills, such as fine motor …

Genome-Wide Association Study Of Copy Number Variations In Parkinson’S Disease, Zied Landoulsi, Ashwin Ashok Kumar Sreelatha, Nicole Kuznetsov, Claudia Schulte, Dheeraj Reddy Bobbili, Ludovica Montanucci, Costin Leu, Lisa-Marie Niestroj, Emadeldin Hassanin, Cloé Domenighetti, Pierre-Emmanuel Sugier, Milena Radivojkov-Blagojevic, Peter Lichtner, Berta Portugal, Connor Edsall, Jens Krüger, Dena G Hernandez, Cornelis Blauwendraat, George D Mellick, Alexander Zimprich, Walter Pirker, Manuela Tan, Ekaterina Rogaeva, Anthony Lang, Sulev Koks, Pille Taba, Suzanne Lesage, Alexis Brice, Jean-Christophe Corvol, Marie-Christine Chartier-Harlin, Eugenie Mutez, Kathrin Brockmann, Angela B Deutschländer, Georges M Hadjigeorgiou, Efthimos Dardiotis, Leonidas Stefanis, Athina Maria Simitsi, Enza Maria Valente, Simona Petrucci, Letizia Straniero, Anna Zecchinelli, Gianni Pezzoli, Laura Brighina, Carlo Ferrarese, Grazia Annesi, Andrea Quattrone, Monica Gagliardi, Lena F Burbulla, Hirotaka Matsuo, Akiyoshi Nakayama, Nobutaka Hattori, Kenya Nishioka, Sun Ju Chung, Yun Joong Kim, Lukas Pavelka, Pierre Kolber, Bart Pc Van De Warrenburg, Bastiaan R Bloem, Andrew B Singleton, Dan Vitale, Mathias Toft, Lasse Pihlstrom, Leonor Correia Guedes, Joaquim J Ferreira, Soraya Bardien, Jonathan Carr, Eduardo Tolosa, Mario Ezquerra, Pau Pastor, Karin Wirdefeldt, Nancy L Pedersen, Caroline Ran, Andrea C Belin, Andreas Puschmann, Carl E Clarke, Karen E Morrison, Dimitri Krainc, Matt J Farrer, Dennis Lal, Alexis Elbaz, Thomas Gasser, Rejko Krüger, Manu Sharma, Patrick May

Faculty, Staff and Student Publications

We investigated the role of copy number variations (CNVs) in Parkinson's disease (PD) using genotyping data from 10,815 patients (2731 early-onset PD, EOPD) and 8901 controls from the COURAGE-PD consortium. CNVs were analyzed using a sliding window genome-wide association and burden approach. No genome-wide significant CNVs were detected in the overall cohort, but a robust deletion spanning exons 2-6 of PRKN was identified in EOPD cases, validated by MLPA, and replicated in the GP2 dataset (23,089 cases, 18,824 controls). CNV burden was significantly enriched in PD-related genes, primarily driven by PRKN, with the strongest effect observed in EOPD. PRKN CNV …

An Educational Intervention To Increase Nurses’ Knowledge And Confidence Of Patient Mobility, Debbie Ann Pytak

Walden Dissertations and Doctoral Studies

Immobility is a significant concern given that nearly half of all hospitalized adults are immobile during their hospitalization, placing them at increased risk for adverse outcomes. As a result, it is critical for nurses to implement strategies that promote safe, structured patient mobility. Thus, the purpose of this Doctor of Nursing Practice (DNP) project was to determine if an educational intervention focused on patient mobility and standardized mobility tool utilization increased knowledge and confidence among nursing staff in an acute care setting. Ten participants volunteered to attend the educational intervention. The average age of the participants was 44.30 years (SD …

The Impact Of State And Federal Policies On Academic Researchers: Findings From A National Survey, Dylan Ruediger, Chelsea Mccracken, Jonathan Barefield

Copyright, Fair Use, Scholarly Communication, etc.

Key findings

● State and federal policies targeting divisive concepts or DEI are shaping research agendas at scale and across disciplines. Twenty percent of all respondents, and 29 percent of researchers working in states with divisive concepts or similar laws, reported having avoided certain research topics because of state laws and policies.

● Eight percent of respondents representing a wide range of disciplines reported having had a federal grant cancelled in 2025.

● Eleven percent of respondents reported that federal and state policies restricting research activities are compelling them to seek employment out of state, to leave the academy, or …

Analyzer-Less X-Ray Interferometry With Super-Resolution Methods, Murtuza S. Taqi

LSU Master's Theses

X-ray interferometry provides valuable information on attenuation, small-angle scattering, and differential phase contrast. This multi-modal contrast can aid in many clinical applications, such as lung diseases and breast cancer. However, standard inter- ferometry has an analyzer grating that can increase the dose requirement to maintain the same image quality as a standard X-ray. We propose the use of super-resolution methods for X-ray grating interferometry without an analyzer, with detectors that fail to meet the Nyquist sampling rate needed for traditional image recovery algorithms. Detector phase- steps are used to nominally recover the sampling and iteratively recover the visibility and the …

From Tradition To Transition: Evaluating Culinary Medicine As A Tool For Metabolic Health Among Nigerian Immigrants In The United States And The United Kingdom, Simi Oduwole M.S.

Department of Nutrition Student Projects

This scoping review examines existing publications to evaluate whether Culinary Medicine can be used as a tool for metabolic health among Nigerian immigrants in the United States and the United Kingdom. Nigeria is one of the fastest-growing populations globally, with increasing migration to high-income countries such as the United States and the United Kingdom. Evidence suggests that Nigerian immigrants experience a rise in diet-related chronic diseases, including obesity, diabetes, and cardiovascular disease, as duration of residence increases. This phenomenon is often attributed to dietary acculturation and shifts toward Westernized eating patterns. This scoping review evaluates whether culinary medicine can mitigate …

Maternal Inflammation Alters Nuclear And Mitochondrial Dna Methylation Patterns In Neonatal Brain Monocytes, Andrew Ebenezer, Jonathan Hicks, Brooke Hollander, Alexander Hone, Mona Batish, Robert Akins, Adam Marsh, Elizabeth Wright-Jin

Department of Medicine Faculty Papers

Neonatal hypoxic ischemic encephalopathy (HIE) is a common birth complication that can cause death or lifelong disabling conditions like cerebral palsy, epilepsy, and autism. It is well established that maternal infection and inflammation are significant risk factors for HIE but reasons for this increase in neurological risk to the offspring remain unknown. Inflammation or infection are associated with epigenetic changes and may contribute to the increased risk of neurodevelopmental disability in exposed offspring. Here, we analyzed and compared DNA methylation patterns in brain monocytes isolated from control, maternal immune activation (MIA), and an inflammation sensitized HIE (IS-HIE) CF-1 mouse model …

Robust Non-Invasive Cardiac Index Prediction Via Feature Integration And Data-Augmented Neural Networks, Chih-Hao Chang, Mei-Ling Chan, Yu-Hung Fang, Po-Lin Huang, Tsung-Yi Chen, Tsun-Kuang Chi, I Elizabeth Cha, Tzong-Rong Ger, Kuo-Chen Li, Shih-Lun Chen, Liang-Hung Wang, Jia-Ching Wang, Patricia Angela R. Abu

Department of Information Systems & Computer Science Faculty Publications

Concurrent with the rising consumption of ultra-processed, high-calorie diets and the decline in physical activity, obesity and related cardiovascular conditions among young adults have continued to increase, becoming an important global public health concern. This study integrates non-invasive Internet of Things (IoT) sensing devices, including the TERUMO ES-P2000 blood pressure monitor (Terumo Corp., Tokyo, Japan) and the PhysioFlow PF07 Enduro cardiac hemodynamic analyzer (Manatec Biomedical, Poissy, France), with an artificial neural network (ANN) for cardiac index (CI) prediction. Through appropriate data preprocessing and model training strategies, the generalization ability and stability of the proposed CI prediction model were significantly enhanced. …

Corneal Tissue Addition Keratoplasty For The Treatment Of Keratoconus, Michelle Diamandi, Brad H. Feldman

Research Day

Introduction: Keratoconus (KC) is a progressive eye disease where the cornea thins and bulges into a cone shape, causing significant vision distortion, blurred vision, astigmatism, and light sensitivity, and is usually diagnosed in teens and young adults (ages 10-30). Currently, corneal cross-linking (CXL), rigid gas permeable (RGP) or scleral contact lenses for vision correction, and corneal transplant in advanced cases are the primary treatment options for KC. Previous studies have shown significant results in improving vision and corneal steepness in KC using intrastromal inlays, most notably synthetic Intrastromal Corneal Ring Segments (ICRS) and Corneal Allogenic Intrastromal Ring Segments (CAIRS). Like …

Cardiac Arrest In Thyroid Storm: Characterizing A Rare But Survivable Emergency, Andrew Young, Jason Fink, Drew Monteleone-Haught, Melissa Falcon, Sahil Banka

Research Day

Background: Thyroid storm is a life-threatening endocrine emergency with well-documented cardiovascular complications. However, the specific complication of cardiac arrest in the setting of thyroid storm remains poorly characterized in the literature, with no established clinical pathways or management algorithms to guide clinicians. This scoping review aims to identify trends and patterns in the management and outcomes of this rare but potentially survivable complication to inform future guidelines.

Methods: A scoping review of case reports was conducted in accordance with PRISMA-ScR guidelines. A comprehensive literature search was performed across PubMed, Scopus, and Embase using terms combining thyroid storm or thyrotoxicosis with …

Delayed Presentation Of Cervical Myelopathy Diagnosed In A Pain Management Clinic, Clayton Mohler, Ron Lincow, Sarah Kizun

Research Day

Background: Cervical spondylotic myelopathy (CSM) is a progressive condition that occurs due to degenerative changes of the spine that compress the spinal cord, leading to potential permanent neurological damage. It generally occurs in people over the age of 50 and has a wide range of clinical presentations with varying neurological symptoms. Because of its varied presentation, diagnosis is often delayed, resulting in increased morbidity.

Case Presentation: We present the case of a 69-year-old male referred to a pain management clinic by his primary care physician for evaluation of his significant neurological symptoms, including pain, weakness, gait disturbance, and reduced sensation. …

Literature Review: Long-Term Effects Of Circumcised Neonates Vs Uncircumcised Neonates, Jada M. Glenn, Daphne Mlachila

Research Day

INTRODUCTION:

Circumcision is a widely practiced procedure, but as research has progressed, its value beyond a purely cosmetic or cultural purpose has come into question. Outside  of a religious context, circumcision has been popularized by the belief that it has significant medical benefits that justify the permanent removal of the foreskin in a neonate. These benefits include, but are not limited to, a reduction in urinary tract infections, transmission of sexually transmitted diseases, and penile cancer. However, recent studies have shown that these reductions are minimal, especially in countries where AIDS is no longer an epidemic. Other studies have also …

Uremic Striatopallidal Syndrome: A Rare Cause Of Hyperkinetic Movement Disorder In End-Stage Renal Disease, Cohen Chong, Esther Choi, Bhavi Purohit

Research Day

Introduction

Uremic striatopallidal syndrome (USPS) is a rare neurologic complication of end-stage renal disease (ESRD) characterized by bilateral basal ganglia dysfunction and hyperkinetic movement disorders, which may manifest as chorea, dystonia, or parkinsonian features. The underlying pathophysiology is not fully understood but is thought to involve metabolic derangements, uremic toxin accumulation, and disruption of basal ganglia function. Because its presentation can mimic medication-induced symptoms, primary neurodegenerative conditions, or other metabolic encephalopathies, USPS may be underrecognized and misdiagnosed, leading to delays in appropriate management.

Methods

A retrospective review of clinical findings, laboratory data, imaging studies, and hospital course was performed for …

Isolated Unilateral Central Ray Deficiency In A Term Newborn: Distinguishing Symbrachydactyly From Amniotic Band Sequence, Mauricio Soto, Rachael Bonitatibus, Stephanie Suarez, Kevin Bhagratie, Anthony Adetomiwa

Research Day

Introduction

Congenital hand anomalies may arise from intrinsic malformations of limb development or extrinsic disruptive processes. Distinguishing symbrachydactyly—a failure-of-formation malformation—from amniotic band sequence (ABS)—a constrictive disruption—is essential, as pathogenesis, prognosis, and management differ substantially. Although both may present with absent digits, characteristic morphologic patterns allow reliable clinical differentiation. We present a term neonate with unilateral central hand deficiency to highlight key diagnostic features distinguishing these entities in the newborn period.

Methods

A retrospective descriptive case review was conducted of a term male neonate with an isolated upper extremity anomaly. Prenatal records, delivery documentation, newborn examination findings, and postnatal radiographic imaging …

A Case Of Radiation-Induced Optic Neuritis (Rion) Managed With Hyperbaric Oxygen Therapy, Zachery M. Casella, Dallin S. Lindahl

Research Day

Case Description/Objective: A 58-year-old African American man with a history of left skullbase meningioma presented to the emergency department with acute bilateral vision loss on April 16. He completed external beam radiation therapy in August 2024, receiving a total dose of 50.4 Gy over one month. MRI of the brain and orbits with and without contrast supported the diagnosis of optic neuritis, most consistent with radiation-induced etiology. He was treated with intravenous methylprednisolone for five days and discharged on oral dexamethasone, pentoxifylline, and vitamin E, with instructions to initiate Hyperbaric Oxygen Therapy (HBOT) as soon as possible at Emory University …

Challenges In Diagnosis: A Review Of Development Of Nut Carcinoma Within The Abdomen And Pelvis, Matthew Alexander, Grace Lynch, Ambika Jokhulall, Donald Penney

Research Day

Background:

NUT Carcinoma is a subtype of squamous cell carcinoma characterized by a translocation of the nuclear protein in testes (NUTM1) gene to form a fusion with an epigenetic reader, most commonly bromodomain-containing protein 4 (BRD4::NUTM1), bromodomain-containing protein 3 (BRD3::NUTM1), or nuclear receptor binding SET domain protein 3 (NSD3::NUTM1). It is a rare and aggressive tumor with a median survival time of 6-9 months and most commonly affects midline structures of the head and neck, though in recent years reports of primary NUT carcinoma within the abdomen and pelvis have been reported. The purpose of this review is to compare …

Vascular Asymmetry In Scoliosis: A Scoping Review Of Anatomical Evidence And Functional Implications, Nick Daneshvar, Olivia Peoples, Nicholas Auge-Dario, Barrington Francis, Mykala Jackson, Michael Abaskaron, Matthew Shelnutt

Research Day

Introduction

Scoliosis alters spinal alignment which may influence the position and function of adjacent vascular structures. Although vascular complications related to scoliosis and its surgical correction have been reported, the potential contribution of scoliosis-associated vascular asymmetry to functional impairment remains unclear. The objective of this scoping review was to synthesize existing literature describing vascular anatomical changes associated with scoliosis and to examine related evidence plausibly linking altered paraspinal perfusion to functional outcomes such as endurance and pain.

Methods

A scoping review was conducted using PubMed with a lower publication date limit of 2005. A primary search identified studies describing vascular …

Teaching In Monochrome: Skin Tone Bias In Medical Training Resources- A Scoping Review, Evelyn O. Orusa, Blessed D. Jordan, David Adelstein

Research Day

Background: Medical training resources demonstrate substantial under-representation of darker skin tones across textbooks, curricula, and educational materials globally. This representational gap may contribute to reduced diagnostic confidence among healthcare providers when assessing patients with diverse skin tones.

Objective: To evaluate the adequacy of skin diversity representation in medical training resources and assess its relationship to healthcare provider diagnostic confidence across different skin tones.

Methods: A review of studies examining skin diversity representation in medical education and provider confidence in diagnosing conditions across varied skin tones. Studies will be identified through comprehensive database searches, including PubMed and Cochrane, and screened for …

I’M Going To Disney World: Regenerative Injection Therapy(Regenexx) Enabling Functional Recovery In Chronic Ankle Dorsiflexion, Marzena Buzanowska, Kévin Borgella

Research Day

Chronic foot drop, weakness or inability to dorsiflex the ankle and toes. Gait deficits such as this can originate from issues in the motor pathway of the cerebral cortex or from injury to peripheral nerves that innervate the foot musculature. The most common cause is L5 radiculopathy and peroneal nerve injury, but can also include lumbar herniation, spinal stenosis, and degenerative nerve diseases. Physical therapy has been the fundamental means of treating this issue with a focus on muscle strengthening, adjusting gait patterns and engaging the mechanisms of neural plasticity to improve muscle activation. In lieu of these methods, Ankle-foot …

Influence Of Background Music On Proton Dose Monitors, Julia Colangeli, Rachel Felder, Nicole Geer, Favour Ihenwe, Shermineh Roodi, Sandra John Baptiste

Research Methods Poster Session 2026

This study examines the effects of background music, particularly varying bass frequencies, on dose monitor accuracy in proton therapy using the Hitachi PROBEAT-FR proton accelerator.

Exploration Of A Relationship Between The Activities Of Trail And 4’-Trifluoromethoxychalcone., Abigail C. Ernst

Undergraduate Theses

Cancer is the overgrowth of dysregulated or mutated cells that affects 1 in 3 Americans. Chalcones are natural products with many possible derivatives, such as 4’-trifluromethoxychalcone (4TF), developed in Dr. Krzysiak’s lab, which exhibit anticancer activity against cancer cell lines. Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) is a tumor surveillance cytokine that acts on two receptor types: death receptors and decoy receptors. One way cancer cells can become resistant to TRAIL is by upregulating decoy receptors and/or downregulating death receptors. In this study, MTS assays evaluated the potential relationship between TRAIL and 4TF that sensitizes A549 cells to TRAIL. The …

Health Professional Education Associations: What Other Professions Teach Us About Building Resources, Community, And Advocacy For Midwifery Educators, Kim Q. Dau, Ms, Cnm

Doctor of Midwifery Advances in Midwifery Projects

In response to a looming health care workforce deficit, several health professions have experienced recent rapid workforce growth. These professions are supported by specialized health professional associations designed to promote educational excellence in the face of rapid growth. In contrast, the midwifery profession does not have dedicated professional organizations to support education programs. The purpose of this study is to better understand the various strategies used by selected health professional education associations and their value to the profession. This can be adapted to promote the growth and excellence of midwifery education in the United States, responding to the need for …

Ms-Gator: Multi-Scale Graph Attention With Topological Reasoning For Segmentation And Classification Of Prostate Cancer Based On Gleason Scores Using Histopathology Images, Sujata Patil, Mahadeva Swamy, Kavitha Sooda, Rajanikanth Vadigepalli, Khalid Nazim Abdul Sattar, Md Rafeeq

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Prostate cancer is one of the prevalent and potentially fatal malignancies, affecting men globally. Accurate segmentation and classification of prostate cancer in histopathology images remain challenging due to complex tissue architecture, staining variability, and high inter-observer differences in manual diagnosis. To address these challenges, this research proposes a Multi-Scale Graph Attention with Topological Reasoning (MS-GATOR) for segmentation and classification of prostate cancer based on Gleason Scores (GS). The MS-GATOR incorporates topological reasoning with hierarchical biological structures by constructing a graph-based representation among three spatial scales such as nuclei, glands, and tissues using Delaunay triangulation to capture both geometric and photometric …

Patient Perception Of Pain Following Extraction And Bone Graft With Or Without Preemptive Ibuprofen: A Randomized Clinical Trial, Samah Rady

Master's Theses (2009 -)

Objective: The purpose of this randomized clinical trial is to investigate the effects of preemptive analgesia on postoperative pain following extraction and ridge preservation and to evaluate the association between dental care-related fear and anxiety, health literacy, fear of pain, and pain catastrophizing with post-operative pain and swelling perception as well as Oral Health Impact Profile-14 (OHIP-14). Materials and Methods: Ibuprofen 600mg (test; n=9) or placebo (n=13) were randomly given one hour prior to extraction and ridge preservation. Preoperatively, patients completed the following questionnaires: Modified Dental Anxiety Scale (MDAS), Oral health-related quality of life (OHIP-14), Fear of Pain (FPQ-III), Pain …

Advocacy, Outreach, And Expansion Of The Michigan Occupational Therapy Association Mental Health Special Interest Section, Isabel Evola

Capstone Projects

The history of occupational therapy (OT) is rooted in supporting mental health, emerging in the United States during World War I. Over time, the practice of OT has evolved in its scope and emerging specialties. The role of OT in mental health is underutilized and misunderstood by professional organizations. However, OT remains a vital service in supporting mental health in psychiatric and non-psychiatric settings. The focus of this doctoral capstone experience (DCE) was to address this gap by advocating for the presence and understanding of OT in mental health through the expansion of the Michigan Occupational Therapy Association (MiOTA) Mental …

Strengthening Leadership And Expanding Engagement: Enhancing Volunteer, Participant, And Donor Involvement In Michigan Victory Games, Abbey Smith

Capstone Projects

This doctoral capstone experience (DCE) addressed organizational development and community engagement within the Michigan Disability Sports Alliance (MiDSA), an adaptive sports nonprofit serving individuals with physical disabilities. The project is relevant to occupational therapy (OT) through its focus on promoting participation, health, and inclusion in meaningful occupations such as sport. A key gap identified was the lack of structured resources to support leadership, inconsistent outreach methods, and limited strategies to reduce barriers for participants, volunteers, and donors.

The objectives of this DCE included developing a centralized data management portal, creating a standardized community outreach presentation, establishing clear board role frameworks, …

Predicting Clinically Significant Prostate Cancer With Or Without Digital Rectal Exam And Mri Data Using Claritydx Prostate Models, Robert J Paproski, Adam Kinnaird, M Eric Hyndman, Adrian Fairey, Leonard Marks, Christian P Pavlovich, Sean A Fletcher, Roman Zachoval, Vanda Adamcova, Jiri Stejskal, Armen Aprikian, Christopher J D Wallis, Desmond Pink, Catalina Vasquez, Perrin H Beatty, John D Lewis

Faculty, Staff and Student Publications

This prognostic study created optimized ensembles of calibrated random forest models to predict clinically significant prostate cancer (csPCa, grade group ≥2 PCa) using total prostate-specific antigen (PSA), free PSA, negative biopsy status, and age, with or without DRE and MRI data. Observational data were aggregated from cohorts in six organizations in Canada, the USA, and Czechia. Prostate biopsies were performed between 2009 and 2024. Risk models (ClarityDX Prostate + DRE, ClarityDX Prostate + MRI, and ClarityDX Prostate + MRI + DRE) were derived (training cohorts n = 1626 to 2191) and validated (validation cohorts n = 378 to 1318) from …

Assessment Of Clinical And Neuroimaging Efficacy Of Treatment Targeting Tau Pathology In Mild Cognitive Impairment And Mild To Moderate Alzheimer’S Disease With Hydromethylthionine Mesylate Using External Control Data, Bjoern O. Schelter, Helen Shiells, Serena Lo, Nafeesa Nazlee, Emily Evans, Peter Bentham, Serge Gauthier, Henrik Zetterberg, Gordon K. Wilcock, Lutz Froelich, Alistair Burns, Emer Macsweeney, Clive Ballard, Jin-Tai Yu, Tay Siew Choon, Vahe Asvatourian, Natalia Muehlemann, Jan Priel, Karin Kook, Tenecia Sullivan, Diane Downie, Sonya Miller, Carol Pringle, John M. D. Storey, Tom Baddeley, Charles R. Harrington, Roger Staff, Anca-Larisa Sandu, Claire Hull, Richard G. Stefanacci, Claude M. Wischik

College of Population Health Faculty Papers

BACKGROUND: Hydromethylthionine mesylate (HMTM) targets tau pathology and also has tau-independent symptomatic activity. A traditional randomised placebo-controlled trial (RCT) was precluded by loss of blinding due to urinary colouration and therapeutic activity at the minimum dose required to maintain blinding.

OBJECTIVE: To evaluate the efficacy of HMTM in participants with mild cognitive impairment (MCI) and mild to moderate dementia due to Alzheimer's disease (AD).

METHODS: Because a traditional RCT was not feasible without loss of blinding, we compared HMTM 16 mg/day in TRx-237-039 with propensity score matched true placebo controls from the FDA-sponsored Critical Path for AD (CPAD) database with …

Galen Of Pergamum: Life, Literature, And Legacy, Elyse Rogers

Ex Sapientia Loqui

Galen of Pergamum was a second-century physician whose work had an enduring impact on the field of medicine. His extensive writings were the primary reference and teaching materials for the medical community for over a millennium. While his ideas were revolutionary for his time, they were eventually outdated. Nevertheless, there was a continued reliance on his authority, which hindered scientific advancement. Galen both advanced the world of medicine with his emphasis on observational analysis and constrained its progress through the profound dominance of his theories.

This paper aims to understand the life of Galen and the significance of his work …

Nitrous Oxide Use In Labor, Aimee Aberson, Janae Cam, Rylie Franken, Rachel Henriksen, Ben Robinson, Pam Hulstein

Celebration of Research

Effective pain management during labor is a critical part of maternal care. It influences the mother’s physical and emotional experiences of childbirth. Epidural anesthesia and intravenous opioids are commonly used as analgesia in laboring mothers, but nitrous oxide (N₂O) has proven to be a safe, noninvasive alternative. It allows mothers to maintain mobility and consciousness while still reducing some pain perception. The purpose of this evidence-based practice project is to evaluate the effectiveness, safety, and satisfaction associated with N₂O use during active maternal labor. It reviews current literature on N₂O use during labor, focusing on maternal and neonatal safety, effectiveness …