Digital Commons Network^™

Aspirin And Preterm Birth Among Pregnant People With Increased Heat Exposure: Secondary Analysis Of A Randomized Clinical Trial, Gabriella Meltzer, Luke Duttweiler, Sarah Saleem, Kartik Shankar, Manolo Mazariegos, Antoinette Tshefu, Jackie Patterson, Elwyn Chomba, Waldemar Carlo, Shivaprasad Goudar, Richard Derman, Archana Patel, Patricia Hibberd, Edward Liechty, Fabian Essamai, Edwin Asturias, Denise Babineau, Janet Moore, Cascade Tuholske, Andrew Zimmer, Brent Coull, Elizabeth Mcclure, Robert Goldenberg, Nancy Krebs, Matthew Hoffman, Blair Wylie

Global Health Articles

IMPORTANCE: Scalable interventions are urgently needed to mitigate the adverse effects of heat on pregnancy and newborn health.

OBJECTIVE: To evaluate whether low-dose aspirin modifies the association between heat exposure and preterm birth.

DESIGN, SETTING, AND PARTICIPANTS: This secondary analysis of the Global Network for Women's and Children's Health Research Aspirin Supplementation for Pregnancy Indicated Risk Reduction in Nulliparas (ASPIRIN) randomized, double-blinded, placebo-controlled clinical trial was conducted from March 2016 to June 2018. Statistical analyses were performed from June 2024 to June 2025. The study settings included the Democratic Republic of Congo, Zambia, Kenya, Guatemala, Pakistan, and Belagavi and Nagpur, …

Patterns Of Acquisition For /ɹ/ Across Phonetic Contexts, Hailey Nielson

All Graduate Reports and Creative Projects, Fall 2023 to Present

Purpose: 

This study examined longitudinal changes in /ɹ/ production (i.e., the “r” sound) among 14 children aged five to seven at risk for persistent speech sound disorders (SSDs). Children at risk for SSDs show slower or atypical development of /ɹ/, yet little is known about which early patterns predict persistent difficulty, making it difficult for clinicians to prioritize caseloads and provide timely intervention. Using perceptual accuracy ratings across varied /ɹ/ contexts, we modeled growth in /ɹ/ accuracy across different word contexts and evaluated the extent to which early accuracy and changes in /ɹ/production predicted mastery at age seven.

Methods: 

Longitudinal …

Seasonal Body Composition And Neuromuscular Changes In High School Wrestlers: Medicine Balls For Fatigue Testing, Courtney Mccall Condie Carroll

All Graduate Reports and Creative Projects, Fall 2023 to Present

This study examines the effects a single wrestling season has on high school athletes’ body composition, muscle quality, membrane capacitance, and neuromuscular performance, and whether instrumented medicine balls are sensitive enough to serve as a field test for chronic fatigue. Twenty-five high school wrestlers (males=18, females=7) were recruited and assessed pre-season (Pre), mid-season (Mid), and end-of-season (Post). Outcome measures included body mass, fat-free mass, fat mass (via bioelectrical impedance spectroscopy), echo intensity (EI, via B-mode ultrasound) of the vastus lateralis (VL) and biceps brachii (BB), and countermovement rotational and backward-overhead throws with medicine balls instrumented with accelerometers.  Repeated measures ANOVA …

Understanding Vaccine Hesitancy In Veterinary Medicine: A Review Of Client Attitudes, Grace Moore

Undergraduate Honors Capstone Projects

Uncertainty toward vaccination, long recognized as a public health concern in human medicine, is increasingly recognized within veterinary contexts, posing risks to both animal and community health. This literature review examines the development, causes, and implications of reduced vaccine confidence in veterinary medicine, with emphasis on small animal and some large animal practices. The review combines historical and current research to explore how vaccination perceptions have evolved among veterinarians and clients, and how factors such as the COVID-19 pandemic have shaped current attitudes.

The literature highlights recurring themes surrounding vaccine reluctance in veterinary settings. Client perceptions of safety, efficacy, and …

Challenging Myths In Speech-Language Pathology: A Scientific Review Of Augmentative And Alternative Communication (Aac) Use, Bilingualism, And Late Talking, Mariah Morris

Undergraduate Honors Capstone Projects

Persistent myths within the field of speech-language pathology continue to influence clinical decision-making and contribute to biases experienced by both providers and clients. This scientific review examines common misconceptions surrounding late talking, bilingualism, and augmentative and alternative communication (AAC) by evaluating current evidence-based research. Specifically, this review addresses three central questions: Do children outgrow late talking? Does bilingualism cause language delay in children? Does AAC hinder speech development? 

An analysis of multiple peer-reviewed studies revealed little statistical support for the belief that bilingualism or AAC use causes language delays. Instead, research indicates that factors such as limited access to language-rich …

Food-Form Delivery Of Spore-Forming Probiotics As An Alternative To Gavage In Animal Models, Aubreyona Faith Migliori Skalka

All Graduate Theses and Dissertations, Fall 2023 to Present

Western dietary patterns are characterized by nutrient-poor, calorie-rich diets and have been linked to poor health outcomes and gut inflammation phenotypes. Probiotics are often taken to support gut health, but many beneficial bacteria do not survive transport through the digestive system to produce any effect. Spore-forming bacteria, such as Bacillus coagulans, are more resilient due to their hardy outer coat which aids in survival through many obstacles encountered in the gastrointestinal tract, including acidic stomach conditions. In research studies, probiotics are usually given to mice through a procedure called oral gavage, where a tube is used to deliver the …

Connecting With Augmentative And Alternative Communication Users: An Internship Report, Karaline Kerzie

Communication Disorders and Occupational Therapy Undergraduate Honors Theses

This article evaluates and reflects on personal experiences working with children with autism in an early intervention, multidisciplinary setting. Implementation of Applied Behavior Analysis, Speech-Language Pathology, Augmentative and Alternative Communication, and Occupational Therapy techniques created a multifaceted and comprehensive intervention environment in a free-clinic setting.

Supporting An Inclusive Summer Camp For Children With Developmental Disabilities Who Use Aac And Their Neurotypical Peers: A Practice-Based Report, Jessica Hicks

Communication Disorders and Occupational Therapy Undergraduate Honors Theses

For my honors research, I completed an internship in an augmentative and alternative communication (AAC) lab at the University of Arkansas. For most of my internship work, I helped support an inclusive AAC summer camp for children with and without developmental disabilities, such as autism, for whom speech does not fully meet their communication needs. AAC includes high-tech tools such as communication apps on tablets that serve as speech-generating devices (SGDs). SGDs were used by many of the AAC summer camp participants with developmental disabilities. In this report, I will provide background information on AAC and developmental disabilities. I will …

Artificial Intelligence In Dental Education: A Literature Review Of Global Adoption, Pedagogical Outcomes, And Ethical Implications, Betti Shahin, Jeremiah D. Ghodsi, Toleen Mazloum, Denise Hale

Journal of Educational Leadership in Action

Background: Artificial intelligence (AI) is revolutionizing many fields by enabling machines to accomplish tasks that previously required human intelligence, such as learning, decision-making, and problem-solving. In dentistry, AI is increasingly applied to diagnostics, treatment planning, and clinical training. Its integration enhances educational experiences for students while supporting more accurate and efficient patient care.

Objective: This review synthesizes recent research on AI in dental education, highlighting global adoption trends and key pedagogical, ethical, and practical considerations.

Conclusion: AI has significant potential to enhance dental education through innovative teaching, clinical training, and data-driven decision-making. Effective integration depends on institutional …

Assessing The Preparedness Of New Graduate Physical Therapists For Primary Care Physical Therapy Roles, Hannah Ellen Snobeck, Olivia Mavis Manuel, Rachel Jean Dukart, Samantha Marie Krogfoss, Logan Nicole Redding, Haley Paige Hase, Reese Paige Richards

Physical Therapy Scholarly Projects

Background and Purpose: The growing shortage of primary care providers in the United States has led to increased discussion about expanding the role of physical therapists (PTs) in primary care. Physical therapists have advanced diagnostic and musculoskeletal expertise that helps them succeed in these roles. This study aimed to assess how new graduates perceive their readiness to practice as primary care providers and to identify the education and experiential factors that shape this.

Methods: Using a qualitative research design guided by self-perception theory, semi-structured interviews were conducted with three physical therapists who graduated between 2022 and 2024. Participants were asked …

Impact Of Intracranial Pressure Monitoring On 30-Day Mortality In Severe Traumatic Brain Injury: A Retrospective Cohort Study In Kenya, George Ongas, Idris Chikophe, Jacqueline Mavuti, David Olunya, Mubashir Qureshi, Beverly Cheserem, Edwin Mogere

General Surgery, East Africa

OBJECTIVE The objective of this study was to evaluate 15-year trends in epidemiology, baseline severity, management, and outcomes of severe traumatic brain injury (sTBI) at a Kenyan tertiary center, and to determine the impact of invasive intracranial pressure (ICP) monitoring on 30-day mortality in a low- and middle-income country (LMIC) context.

METHODS A retrospective quasi-experimental cohort analysis of consecutive sTBI admissions (postresuscitation Glasgow Coma Scale [GCS] score ≤ 8, age ≥ 13 years) from January 1, 2010, to December 31, 2024, was conducted. This time period was divided into two eras: era 1 (2010–2014), premonitoring, and era 2 (2015–2024), routine …

Creating Supportive Environments For Children To Bloom: A Trauma-Informed Occupational Therapy Approach, Morgan Benson

Occupational Therapy Capstone Presentations

A significant number of children receiving occupational therapy services have histories of adverse childhood experiences (ACEs), including neglect, abuse, frequent changes in caregiving environments, and exposure to chronic stressors. These experiences can strongly affect sensory processing, emotional regulation, behavior, and participation in meaningful daily occupations. These challenges are often made more complex by limited caregiver education, inconsistent access to trauma-informed resources, and differences in therapist confidence when addressing trauma in pediatric practice. Occupational therapy practitioners are well-positioned to support these needs through holistic, occupation-based, and client-centered care that considers sensory, emotional, environmental, and developmental factors. The purpose of this capstone …

Integrating Trauma-Informed Care Into Pediatric Occupational Therapy, Kylie H. Rodig

Occupational Therapy Capstone Presentations

This capstone project examined how trauma-informed care (TIC) and Trust-Based Relational Intervention® (TBRI) can be integrated into pediatric occupational therapy to better support children impacted by trauma. The project was guided by the question of how structured trauma-informed strategies, clinical tools, and caregiver education influence therapist understanding and application in practice.

A mixed-methods approach was used, incorporating TIC- and TBRI-informed interventions during pediatric treatment sessions, trauma-informed evaluations, and ongoing reflective practice. Data were gathered through pre- and post-surveys, informal staff feedback, and reflective logs to capture changes in knowledge, confidence, and clinical application over time.

Results showed clear improvements in …

A Pilot Project On Improving Icu Nurses’ Confidence In Early Defibrillation, Adetutu Obadina

Doctoral Projects

Early recognition of shockable cardiac rhythms and timely defibrillation are critical components of effective resuscitation during in-hospital cardiac arrest. Despite established guidelines from the American Heart Association (AHA), nurses may experience uncertainty or reduced confidence when identifying shockable rhythms and delivering timely defibrillation during cardiac arrest events. The purpose of this project was to examine whether a structured educational intervention incorporating simulation-based training could improve intensive care unit (ICU) nurses’ confidence and knowledge in recognizing shockable rhythms and performing timely defibrillation. A pre-and post-intervention design was implemented among ICU nurses at a large academic medical center between September and October …

A Literature Review Of Estrogen Synthesis And Metabolizing Enzymes Produced By The Human Gut Microbiome And Their Correlation With Cancer, Rebecca Cederberg

Capstone Experience: Master of Public Health

The link between estrogen and cancer initiation or progression has been well established; such that the World Health Organization’s International Agency for Research on Cancer (WHO IARC) has classified several estrogen therapies and estrogenic compounds as group 1 carcinogens. Estrogen and/or its receptors have been associated with reproductive cancers such as breast, ovarian, endometrial, and prostate, as well as lymphomas, lung, and colon cancers. Additionally, elevated levels of estrogen and altered gut microbiomes are also associated with increased rates of breast cancer. More recently, microbial genes that are capable of synthesizing estrogen and deconjugating estrogen metabolites have been identified, and …

Use Of Electroencephalography To Evaluate Neural Correlates Of Attention In The Oddball Paradigm, Folsom J. Berry

Honors Theses

Electroencephalography (EEG) and Event-Related Potentials (ERP) are tools used to study and analyze cognitive processing. EEG measures neuroelectric brain activity from the scalp, while ERPs are time-locked averages that are used to isolate neural responses to stimuli. The P300 (P3) component (positive waveform elicited at 300 milliseconds (ms)) is the primary ERP component. This thesis project had two main objectives. The first objective was to develop conceptual and technical competency in EEG/ERP theory, data acquisition, and processing. The second objective was to implement the visual oddball paradigm through experimental demonstration. This experiment tested the hypothesis that infrequent target stimuli will …

Bulletin Ninth District Ny May 2026

Bulletin of the Ninth District Dental Association

In the May 2026 issue, the reader will find the following feature articles:

• "ADA Lobby Day 2026"
• "Dentistry for Individuals with Special Needs"
• "ADA Trustee Corner"
• "CE Navigator FAQ"
• "NYSDA Wins in 2025"
• "Peer Review and Quality Assurance: What is it and Why is it an Important Member Benefit?"

Also included are your monthly President's Message, event updates, continuing education opportunities, membership news and classifieds.

Dentistry For Individuals With Special Needs, William J. Maloney

Bulletin of the Ninth District Dental Association

Dentists have a profound responsibility to champion special needs patients through patience, trust, accessibility, collaboration, and individualized care—recognizing that thoughtful accommodations and compassion are essential to safe treatment, dignity, and lifelong oral health.

This article discusses social-emotional, practical, and clinical considerations for best serving patients with disabilities. A list of tips specifically for improving the experience of dental visits for pediatric patients with developmental disabilities is included.

Metabolic And Replicative Constraints On Pathogen Virulence: Isoleucine Catabolism In Shigella And Comparative Tanapoxvirus Replication In Cell Cultures, Benecia Angelica

Masters Theses

Pathogens survive by balancing metabolic demands with environmental challenges that shape their virulence and adaptability. Shigella flexneri, a highly infectious human pathogen responsible for severe diarrheal disease worldwide, utilizes branched-chain amino acid (BCAA) metabolism to withstand stress conditions encountered within the host environment. In this study, we explored the Shigella isoleucine catabolism pathway by knocking out four genes in the S. flexneri isoleucine catabolic pathway (ilvE, fadA, fadD, and acnB) and examining their metabolism and virulence. We found that the ilvE and acnB mutants displayed reduced metabolic activity and smaller plaque size, while the fadD mutant showed decreased invasion. In …

A Quality Improvement Project For Seizure Protocol, Billiejo N. Bates

Doctor of Nursing Practice Scholarly Project

Seizure disorders are often misunderstood and can carry stigmas, especially in institutional care settings where direct care staff knowledge and preparedness affect patient safety and quality of life. At Parsons State Hospital and Training Center (PSH&TC), staff lacked standardized training on seizures, and no formal seizure response protocol existed, which created gaps in care and reduced staff confidence. The purpose of this project was to improve staff understanding of seizures and establish a clear, consistent procedure for responding to seizure events. A pre- and post-survey design was used to measure staff knowledge, awareness, and confidence regarding seizure management. Between the …

Shedding Light On The Invisible Work Of Peer Recovery Support Specialists Through The Design Of A Point Of Care Technology., Jessica A Pater, Elisabeth Andrews, Michelle Drouin, Mindy Flanagan, Dana Albright, Rachel Pfafman, Jeanne Carroll, Erik Hess, Tammy R Toscos

Health Services and Informatics Research

Peer Recovery Support Specialists (PRSSs) are certified professionals that provide social, informational, and logistical supportto people in recovery fromsubstance use disorders. In this study, we report the findings from design work completed with a teamof PRSSsto define workflowand informationalneeds for the developmentofa novel point of care software. Through our qualitative research we uncovered a significant amount of undocumented work that is necessary for a PRSS to provide individualized support to their clients. Thus, much PRSS work is not quantified and rendered "invisible." We present technology design strategies that help quantify these tasks and illuminate the complexity of PRSS work.

Medical Simulation In Toxicology: Enhancing Clinical Competence, Decision Making And Patient Care In Resource-Limited Settings, Rakesh Ghimire, Anjana Thapa, Sanjeev Kharel, Shristi Kharel Ghimire, Rabin Basnet, Farshad Mazda Shirazi, Allan J. Hamilton

Research outputs 2022 to 2026

Medical simulation has emerged as a transformative approach in toxicology education. By providing immersive, hands-on experience, simulation enhances learner engagement, critical thinking, and long-term knowledge retention while offering a safe environment to practice clinical decision-making without jeopardizing patient safety. Despite these advantages, the integration of simulation-based training remains limited in low-and middle-income countries (LMICs) due to resource constraints, lack of standardized curricula, and limited access to high-fidelity simulators. Additionally, little research has explored its optimal application in these settings. This review explores available evidence regarding the effectiveness of medical simulation in the diagnosis and treatment of toxicological emergencies in LMICs. …

Key Insights From The International Icu Diary Conference 2025, Peter Nydahl, Bev Ewens, Anne Sophie Debue, Xavier Fiorilla, Kristin Gabriel, Alessandro Galazzi, Louise Gallie, Nikolas Groth, Carly Hickey, Mark Hudson, Fiona Lynch, Nicola Maxwell, Margo Van Mol, Caroline Renner, Louise Rose, Kate Tantam, Lioudmila Karnatovskaia, Christina Jones

Research outputs 2022 to 2026

We report on the 2025 International ICU Diary Conference that provided a comprehensive update on current knowledge, innovations and global practices related to ICU diaries. Held in a 6-week online format, the event featured 23 speakers and was attended by mean 69.7 (SD 20.5) participants per session. Topics included development of ICU diaries, use in special settings, digital diaries, survivors' and families' experiences, Post-Intensive-Care Syndrome and follow-up and implementation projects. Highlights were innovative solutions for digital diaries and the report of persons with lived and living experiences with diaries, changing the focus on humanising critical care. Relevance for Practice: ICU …

The Influence Of Valence On Action Control: A Comparison Of Simon Effects In The Extrinsic Affective Simon Task (East) And The Spatial Simon Task, Yaara Aleissa

College of Arts & Sciences Senior Theses

People adjust their thoughts and actions in response to a changing environment every day and emotions may influence these actions. Understanding how emotion impacts action control in situations where emotion is central to the action (task-relevant) compared to when it is present in the environment as distracting information (task-irrelevant) is essential. Currently it is unclear when emotion most significantly modulates action control. This study seeks to compare how valence (positive versus negative emotion) impacts action control performance when valence is task-relevant and task-irrelevant by using two modified versions of the Simon conflict task.

The Simon task is a paradigm to …

Parkinson’S Disease And Its Treatments: An Overview, Nathaniel Cook

Senior Honors Theses

Parkinson’s disease (PD) is a neurodegenerative disease closely associated with the accumulation of α-synuclein in neurons, and inhibition in the release of dopamine, a key neurotransmitter of the nervous system. Disruption in dopamine signaling can cause cognitive and motor dysfunctions, with tremor, bradykinesia, and rigidity being the most observable effects. There is no permanent treatment for PD, constituting the need for further research to improve current pharmaceutical approaches and possibly develop a cure. Main areas of research include improving medication via delivery methods, genetic mutation using CRISPR, and adaptive deep-brain stimulation. Recent developments and applications in these areas will be …

Understanding Delays In Emergency Department Care: A National Analysis Of Wait Times, Gregory Forsberg

Mathematics, Statistics, and Computer Science Honors Projects

Emergency department (ED) wait times remain a persistent bottleneck in the United States healthcare system, impacting patient outcomes, hospital efficiency, and equitable access to care. This study analyzes nationally representative data from the National Hospital Ambulatory Medical Care Survey (NHAMCS), a complex, multi-stage probability sample. Using survey-weighted analyses and predictive modeling, we examine the effects of patient characteristics, triage acuity, and visit timing. Results indicate that operational and system-level factors, including hospital capacity, geographic region, and temporal variation, are among the most influential predictors of ED wait times

Ai×Life 2026: Advances In Computational Biology Across Scales For Life & Health Sciences, Suma Mohan S., Devika N. T., Pranavathiyani G.

Conference Proceedings

Book of Abstracts of the International Conference, AIxLife 2026: Advances in Computational Biology Across Scales for Life & Health Sciences, held on 17–18 April 2026, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, INDIA 

About the Conference

Conventional computational biology laid the foundation for biological data analysis through statistical models, algorithms, and curated databases, enabling insights into genes, proteins, and pathways. Today, the integration of artificial intelligence, spanning machine learning, deep learning, and large language models (LLMs) is driving a transformative shift across biological scales, from atomic and molecular interactions to pathways, cellular systems, organisms, and populations.

AI-powered approaches …

A New Generation Of Inhaled Vaccines, Clark Chapman

Undergraduate Honors Thesis Collection

Vaccines have stood the test of time as being one of the greatest developments in health history. Delivery of these life-saving vaccines has primarily remained reliant on intramuscular administration, which has its own collection of shortcomings. When considering what vaccine formulation is best suited to be a widely accessible and effective tool in the fight against respiratory pathogens, current data and science points to a number of improvements available to us. These improvements include:

• An inhaled formulation, uniquely stimulating mucosal immunity

• A dry powder formulation to improve long-term stability

• A live attenuated vaccine to increase immunogenic response …

Immersive Visualization Of Cardiac Segmentation And Analysis, Brandon Norman

Theses and Dissertations

Coronary artery disease remains one of the leading causes of death worldwide, making early detection and treatment critical to reducing mortality. While coronary angiography remains the gold standard procedure for diagnosing coronary artery disease, less invasive methods such as coronary computed tomography angiography and virtual fractional flow re-serve continue to improve. However, taking full advantage of volumetric coronary computed tomography angiography data requires extensive post-processing before the data can support geometric modeling, hemodynamic simulation, and analysis. Existing Open-Source Appli-cations provide powerful tools for these tasks, but their interaction models remain largely desktop based, restricting users to 2d manipulation and hindering …

Plasma Constituents Promote Endothelial Thromboinflammatory Dysfunction After Hemorrhagic Shock, Kelly E Sanders, Marissa D Pokharel, Baron K Osborn, Yao-Wei Wang, Charles E Wade, Lucy Z Kornblith, Mitchell J Cohen, Jessica C Cardenas

Faculty, Staff and Student Publications

Background: Hemorrhagic shock (HS) following traumatic injury is hallmarked by innate immune activation, hypercoagulability, and thromboinflammatory complications. To date, the direct link between HS, injury severity, and endothelial cell (EC) contributions to thromboinflammation remains poorly understood. The goals of this study were to determine the impact of injury severity and HS on endothelial-mediated thromboinflammation and examine whether these changes increase the propensity for thrombosis.

Methods: Plasma from 89 male trauma patients, stratified by HS and injury severity, and 10 healthy subjects were assessed for inflammatory mediators by BioPlex. Human lung microvascular endothelial cells were exposed to patient plasma for 4 …