Digital Commons Network^™

Blue Light Exposure, Eye Strain, And Sleep Quality: Evaluating The Effectiveness Of Blue-Light Filtering Lenses, Sara Rozalowski

Honors Capstones

This study employs a literature review to critically evaluate the benefits of blue light–filtering lenses and to determine whether their use against eye strain and toward sleep quality is supported by empirical evidence. The aim of this research is to provide evidence-based information to better inform patients regarding the clinical utility and practical applications of blue light filtration in corrective lenses.

From Exploitation To Healing: Mental Health And Resilience Among Native American Survivors Of Sex Trafficking, Katelin A. Stoebner

Honors Thesis

The mental health impacts of sex trafficking on Native American survivors and pathways to resilience are important to understanding healing. Native Americans are disproportionately affected by sex trafficking due to systemic inequities, historical trauma, and socioeconomic vulnerability. Using interviews with 47 Native survivors conducted as part of a larger Office on Violence Against Women project, this study analyzes the mental health challenges and recovery strategies identified by participants. Findings reveal that survivors commonly experience significant psychological effects, including post-traumatic stress disorder (PTSD), depression, and anxiety. Among participants, PTSD emerged as the most frequently reported condition, followed by depression and anxiety, …

Care, Control, And The Racial Regulation Of Black Women’S Reproduction In American Medicine, Rheya K. Wilk

Honors Thesis

Black women in the United States continue to experience disproportionately high rates of maternal mortality, negative reproductive healthcare experiences, and documented disparities in medical treatment. From slavery through the twenty-first century, American medicine has repeatedly positioned Black women’s reproduction as a site of regulation, rather than care, making medical mistrust among Black women a rational response to a long history of institutional conflict embedded in American medicine. Drawing on medical history and bioethical analysis, this thesis traces reproductive abuse across distinct, yet connected, eras. Beginning with antebellum gynecological experimentation on enslaved women, it demonstrates how racialized assumptions about pain and …

How Screen Time Affects Language Development In Children Ages Three To Five Years, Alyssa R. Sherman

Honors Thesis

Screen time has become an increasingly prominent part of early childhood, particularly following shifts in daily routines after the COVID-19 pandemic. This literature review examines how screen time affects language development in children ages three to five, a critical developmental period for expressive and receptive language skills. The review synthesizes current research on the use of passive and interactive screens and their associations with language acquisition, cognitive development, social communication, and physical health outcomes. Across studies, a consistent pattern emerges: excessive screen time is strongly associated with delayed language milestones, reduced social communication skills, poorer sleep quality, and increased physical …

Exploring The Neural Correlates Of Motor Learning, Brooklyn R. Thomas

Honors Thesis

The left anterior supramarginal gyrus (aSMG) is recognized as a fundamental cortical region involved in the mastery of skilled tool-use. Although various research studies have revealed that anodal transcranial Direct Current Stimulation (atDCS) over the cortex has the potential to boost manual dexterity, the impact of stimulating the aSMG is less understood in relation to the learning process. Within this study, there was a chopstick-based marble task to discover if atDCS applied to the left aSMG was capable of facilitating the acquisition of a novel motor skill. Concurrent electroencephalography (EEG) was used to measure the changes in neural synchrony within …

The Effects Of Acute Exercise And Observation On Procedural Learning: Considerations Of Biological Sex, Madeline R. Gossett

Honors Theses

As memories are formed or learning progresses, neurons within the brain establish a strong connection in what is referred to as a “neural engram.” This neural engram can be strengthened or weakened by certain physiological factors. Dopamine, for example, is released during physical exercise or when positive reinforcement is incorporated (Greenwood, 2019). This is a neurotransmitter that leads to a stronger connection between neurons, which in turn leads to a stronger memory formed in the brain. These physiological relationships that contribute to cognition are still being discovered, so research in this area is ongoing (Guskjolen and Cembrowski, 2023).

Memory is …

Menstruation Behind Bars: A Mixed-Methods Study On Menstrual Product Access And Distribution Practices In Mississippi County Jails, Eron Hendrix

Honors Theses

This study examines menstrual product access and distribution practices in Mississippi county jails. It highlights the impact of period poverty as a critical yet underexplored public health and human rights issue within the corrections system. While existing research documents widespread inequities in access to menstrual products women’s healthcare in the correctional system, limited attention has been given to menstrual health at the local jail level. Using a mixed-methods approach, this study combines qualitative interviews with jail correctional staff and quantitative survey data from formerly incarcerated women to better understand institutional practices and lived experiences.

Interviews were conducted with sheriffs, jail …

Care Without Barriers: Dei And Cultural Competency In Athletic Training Education Programs, Sydney Hotz

Graduate Theses, Dissertations, and Capstones

In the field of athletic training, cultural competency is a topic that is highly under-researched. Athletic trainers (ATs) are healthcare professionals who provide care in a variety of settings, including secondary schools, where their patient population often includes student-athletes experiencing adverse social determinants of health and barriers to healthcare access. Only since 2022 has the governing body of athletic training education mandated that programs include cultural competency and DEI education in their programs, and to this day does not require programs to report adherence and methods of implementation. A quantitative, cross-sectional analysis was conducted to assess the relationship between cultural …

Education, Evaluation, And Impact Of A Delegation Learning Session In The Care Pair Model, Tiffany M. Whitney

Doctor of Nursing Practice Projects: College of Nursing

The persistent nurse shortage is forcing the health sector to think about the way care is provided, and teams collaborate. One model, the Care Pair Model (CPM), pairs registered nurses (RNs) with nursing assistants (NAs) to distribute responsibility and provide patient care in a timely manner and with the best quality. Even though the model encourages working together effectively, many nurses still find it difficult to delegate to uncertainty, lack of confidence, or communication barriers. Improving these abilities is essential for fostering trust, ensuring a smooth workflow, and providing for patient and provider needs.

This Doctor of Nursing Practice (DNP) …

The Tortoise, Alexa Gail Colinco

Quill & Scope

For my grandfather, Dr. Joel R. Colinco (1928-2017). The first physician in his family. A man who provided free medical care to all and who continues to do so through the Colinco Medical Mission Outreach. The 2009 Senior Poet Laureate of South Carolina. A deacon and choir director in the Philippines. A painter, tennis player, fisherman, crossword addict, gardener, and so much more. Eternally honored to be guided by his legacy and ethics. (Pang, we'll play Scrabble again in heaven, and I promise I'll spell neighbor correctly this time.)

Quantifying Patient Positioning Errors And Radiation Dose Variation In Cardiac Computed Tomography Angiography, Yasser H. Hadi, Hassan B. Hawsawi, Niamh Moore, Helle Precht, Andrew England, Mark Mcentee

Journal of the Saudi Heart Association

Objectives: Accurate patient centring at the computed tomography (CT) scanner isocentre is essential for optimising radiation dose. This study aimed to quantify positioning errors, assess their relationship with radiation dose, and estimate the potential dose reduction achievable with optimal centring. Methods: This retrospective observational study included adult patients (≥18 years) who underwent electrocardiography (ECG)-gated cardiac CT angiography between January 2023 and July 2025 at a tertiary hospital. Scans were performed using Siemens SOMATOM Force dual-source CT systems. Vertical and lateral deviations from the scanner isocentre were calculated from scout images using integrated analytics within the institutional dose monitoring platform (Qaelum …

Orthographic Representations In American Sign Language Fingerspelling, Zed Sehyr, Lauren Fillet, Kiana Billot-Vasquez, Emily Saunders, Karen Emmorey

Communication Sciences and Disorders Faculty Articles and Research

This study examined fingerspelling accuracy and error patterns in deaf American Sign Language (ASL) signers and written spelling in hearing English speakers to investigate how orthographic representations are shaped by phonological, visual, and motor encoding strategies. Deaf participants (n = 39) completed a fingerspelling repetition task, while hearing participants (n = 35) completed a written dictation task using the same word and pseudoword stimuli. While overall accuracy did not differ significantly between groups, deaf participants exhibited qualitatively distinct error patterns, including higher rates of deletions and transpositions, compared to hearing participants who made more substitution errors. Deaf participants also produced …

The Legacy Of Lead: Lead Exposure's Harmful Effects And Its Concentration In Poc Communities, Layla Sophronia Barber

Student Theses 2015-Present

This thesis examines the disproportionate burden of lead exposure carried by low income, POC communities. The systemic nature of this problem is a symptom of a longstanding legacy of environmental injustice in the United States. Decades of federal neglect are reflected in the higher statistics of lead exposure and poisoning in predominantly black communities. While it is understood that lead exposure poses a serious threat to physical health and early cognitive development, there is a discouraging lack of urgency to remove the toxin from non-wealthy communities. The material covered by this thesis aims to identify and correct the discriminatory social …

Mental Health Screening For The Military Spouse: Prevention In Practice, Lura Allison Mcgrath

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Abstract

In recent years, a focus on mental health has moved to the forefront of healthcare. This is especially true when caring for United States military service members. The military spouses of these service members also struggle and suffer from mental health disorders. However, the mental health needs of military spouses often receive insufficient attention. Research shows military spouses are at an increased risk of developing mental health disorders and/or suffering from mental illness. A large contributor is the impact of the military lifestyle and its challenges for these spouses. However, research also reveals there has been minimal effort put …

Staff Education To Improve Clinical Task Prioritization Among Outpatient Clinical Staff, Adebayo Arowolo

Walden Dissertations and Doctoral Studies

No abstract provided.

Tunable Tripcides Suppress Virulence Factor Secretion During Staphylococcus Aureus Infection And Kill Dormant Cells, Hasan Tükenmez, Taylor M Nye, Suzanne Hickerson, Chloe L P Obernuefemann, Jerome S Pinkner, Karen W Dodson, Michael G Caparon, Scott J Hultgren, Et Al.

2020-Current year OA Pubs

Antimicrobial resistance (AMR) in common bacterial pathogens, including methicillin-resistant

Inflammatory Markers In The Emergency Department And Ptsd Symptoms In The Aurora Study: A Longitudinal Cohort Study, Kristen Nishimi, Stacey L House, Et Al.

2020-Current year OA Pubs

BACKGROUND: Systemic inflammation is hypothesized to contribute to post-traumatic stress disorder (PTSD) vulnerability. Few studies have examined inflammation shortly after trauma as a predictor of later PTSD symptoms. We examined whether inflammation from the emergency department (ED) post-trauma is associated with PTSD symptom severity over the following 6 months.

METHODS: Our sample included 742 AURORA participants, a longitudinal cohort of patients in 29 EDs across the United States after a traumatic stressor, followed up to 6 months. Plasma cytokines were assessed from a study blood draw in the ED: an inflammatory index (standardized sum of generally pro-inflammatory markers interleukin [IL]-6, …

Inflammatory Markers In The Emergency Department And Ptsd Symptoms In The Aurora Study: A Longitudinal Cohort Study, Kristen Nishimi, Sarah Linnstaedt, Thomas Neylan, Lauren Mckibben, Liz Marie Albertorio-Sáez, Ying Zhao, Stacey House, Francesca Beaudoin, Xinming An, Jennifer Stevens, Gari Clifford, Tanja Jovanovic, Laura Germine, Scott Rauch, John Haran, Alan Storrow, Paul Musey, Phyllis Hendry, Sophia Sheikh, Brittany Punches, Robert Swor, Jose Pascual, Mark Seamon, Elizabeth M Datner, Claire Pearson, David Peak, Roland Merchant, Robert Domeier, Niels Rathlev, Brian O'Neil, Paulina Sergot, Leon Sanchez, Steven Bruce, Steven Harte, Ronald Kessler, Karestan Koenen, Kerry Ressler, Samuel Mclean, Aoife O'Donovan

Department of Emergency Medicine Faculty Papers

BACKGROUND: Systemic inflammation is hypothesized to contribute to post-traumatic stress disorder (PTSD) vulnerability. Few studies have examined inflammation shortly after trauma as a predictor of later PTSD symptoms. We examined whether inflammation from the emergency department (ED) post-trauma is associated with PTSD symptom severity over the following 6 months.

METHODS: Our sample included 742 AURORA participants, a longitudinal cohort of patients in 29 EDs across the United States after a traumatic stressor, followed up to 6 months. Plasma cytokines were assessed from a study blood draw in the ED: an inflammatory index (standardized sum of generally pro-inflammatory markers interleukin [IL]-6, …

True North: Full Issue Download

Quill & Scope

Silence is embedded into the life of medical students. Silence pierces the air when you are standing in the back of a patient room observing the conversation, feet aching, wondering if your presence is unnecessary and overwhelming for the patient. We are transient members of the healthcare team. We contribute to patient medical records with out notes and bedside conversations, yet we lack power in the system---the authority to sign orders, be responsible to true coordination of care, the autonomy that residents wield to make healthcare decisions.

It is easy to lose your sense of self in this silence. We …

Values-Based Clinical Ethics: A New Model Of Health And Ethics Consultation For Patients Suffering In Extremis, Adam Trainer

Electronic Theses and Dissertations

This dissertation argues that contemporary clinical ethics is inadequately equipped to support patients suffering in extremis because it relies on an insufficiently discriminating account of health and a constrained model of moral reasoning. Drawing on Bernard Lonergan, it reconceives health as an emergent, multi-layered, heuristic notion shaped by biological, psychological, social, and existential goods. On that basis, it critiques principlism’s global applicability thesis and the undergirding claim that its principles form part of the common morality, arguing that this justificatory structure is philosophically insufficient and practically limited for clinical ethics in cases marked by profound suffering, moral plurality, and normative …

Modalities Of Vision Restoration In Optic Neuropathies And Retinal Disease, Batsheva Rubin, Fabio Lavinsky, Rachel Cain, Ajay E. Kuriyan, Gadi Wollstein, Ronald Zambrano, Joel Schuman

Wills Eye Hospital Papers

Visual impairment affects over 250 million people globally and carries a significant psychosocial and economic burden. In recent years, rapid advancements in biomedical engineering and regenerative medicine have driven the development of innovative therapies aimed at restoring visual function. Here, we first provide an overview of the visual pathway, imaging modalities, and the psychosocial and economic burden of vision loss. Then we review four vision restoration approaches: gene and stem cell therapies, optogenetics, retinal prosthetic devices, and visual pathway electrical stimulation. For each therapeutic approach, the mechanism of action, clinical outcomes, adverse events, and current limitations are discussed. Stem cell …

The Impact Of Patient Navigation On The Hepatitis C Care Continuum In Underserved Populations: A Scoping Review, Deauntaye Jones

Honors Theses

Hepatitis C virus (HCV) remains a significant public health concern and is a leading cause of cirrhosis, hepatocellular carcinoma, and liver transplantation when left untreated. Although direct-acting antiviral therapies have made HCV curable for most patients, many underserved populations continue to experience barriers to diagnosis, linkage-to-care, treatment completion, and sustained virologic response (SVR). This study evaluated how patient navigation programs influence progression through the HCV care continuum among underserved populations. Relevant studies published between 2014 and 2025 were identified through searches of PubMed and Embase using terms related to HCV, patient navigation, linkage-to-care, underserved populations, and treatment outcomes. Following title, …

Hyposense: Multimodal Physiologic And Voc Wearable For Early Hypoglycemia Detection, Nidhi R. Patel

Honors Theses

Hypoglycemia remains a significant safety concern for insulin-dependent individuals, especially when blood glucose declines rapidly during exercise, sleep, or periods of impaired hypoglycemia awareness. Current continuous glucose monitors and automated insulin delivery systems have helped to improve diabetes management, but these technologies primarily respond to glucose trends after they have already started and may not actually provide sufficient warning before symptoms occur. This thesis describes the development of HypoSense, a noninvasive wrist worn wearable concept that is designed to support earlier hypoglycemia risk detection through multimodal physiologic and volatile organic compound emission sensing. HypoSense combines volatile organic compounds/gas sensing with …

Serological Evidence Of Onchocerca Volvulus Exposure And Entomological Indicators Of Parasite Transmission, Didier Kapuku Bakajika

Walden Dissertations and Doctoral Studies

No abstract provided.

Identifying Novel Gene Dysregulation Associated With Opioid Overdose Death: A Meta-Analysis Of Differential Gene Expression In Human Prefrontal Cortex, Javan K Carter, Bryan C Quach, Caryn Willis, Melyssa S Minto, Dana B Hancock, Janitza Montalvo-Ortiz, Olivia Corradin, Ryan W Logan, Consuelo Walss-Bass, Brion S Maher, Eric Otto Johnson

Faculty, Staff and Student Publications

Only recently have human postmortem brain studies of differential gene expression (DGE) associated with opioid overdose death (OOD) been published; sample sizes from these studies have been modest (N = 40-153). To increase statistical power to identify OOD-associated genes, we leveraged human prefrontal cortex RNA-seq data from four independent OOD studies and conducted a transcriptome-wide DGE meta-analysis (N = 272). Using a unified gene expression data processing and analysis framework across studies, we meta-analyzed 20, 098 genes and found 335 significant differentially expressed genes (DEGs) by OOD status (false discovery rate <  0.05). Of these, 66 DEGs were among the list of 303 genes reported as OOD-associated in prior prefrontal cortex molecular studies (e.g., genes/gene families OPRK1, NPAS4, DUSP, EGR). The remaining 269 DEGs were not previously reported (e.g., NR4A2, SYT1, HCRTR2, BDNF). There was little evidence of genetic drivers for the observed differences in gene expression between opioid addiction cases and controls. Enrichment analyses for the DEGs across molecular pathway and biological process databases highlight an interconnected set of genes and pathways linked to orexin and tyrosine kinase receptors through MEK/ERK/MAPK signaling to affect neuronal plasticity.

Left Out And At Risk: Post-Pandemic Continuation Of Organizational Service Reduction In Metropolitan New York City Coincides With Rise In Opiate Use And Mental Health Problems For Latinos, Ruth Lin Campbell, Smita Ekka Dewan

Publications and Research

Increasing opiate use and mental health problems among younger and older Latinos in urban US contexts prompted this investigation into the organizational resources that facilitate help-seeking efforts of Latinos in New York State (NYS). Guided by a Vulnerability Model and a framework of organizational enabling resources, this study used complementary longitudinal and cross-sectional designs. The longitudinal component examined changes in levels of organizational facilitators for Latino substance use disorder (SUD) help-seeking in Downstate NYS across three time periods, while the cross-sectional component compared post-pandemic facilitator levels across service types and regions. A convenience sample of 241 SUD clinicians participated in …

Development Of Novel Plasma Proteomic Biomarkers For Cancer-Associated Thrombosis In An Advanced Cancer Cohort, Preeti, Mrinal Ranjan, Dang Pham, Juan L Bueno, Micheline M Resende, Michael E Scheurer, Christopher I Amos, Chao Cheng, Ang Li

Faculty, Staff and Students Publications

Background: Existing risk models for cancer-associated thrombosis (CAT) show suboptimal performance in selective high-risk populations with cancer. Affinity-based plasma proteomics offers a novel approach for detecting CAT risk.

Objectives: To identify plasma biomarkers for CAT using proximity extension assays in an advanced cancer cohort.

Methods: We performed a nested case-control study using the Olink Explore HT panel. The final cohort included 57 patients with CAT and 113 matched control patients from 5 selected cancer types who had samples collected between cancer diagnosis and chemotherapy initiation. Random survival forest model was used to assess nonlinear associations with CAT in 5416 normalized …

Impact Of Dermatology Access On Dermatofibrosarcoma Protuberans Outcomes, Joseph H. Kelly, Marcus L. Frohm

Scholarship Pathways Program

Impact of Dermatology Access on Dermatofibrosarcoma Protuberans Outcomes

Joseph H. Kelly MD

Mentor: Marcus L. Frohm, MD

Introduction: Dermatofibrosarcoma protuberans is a locally aggressive rare dermal sarcoma with a relatively high rate of local recurrence. Incidence in the United States has been reported around 4 occurrences per million people per year, and recurrence rates have been reported between 2 to 19%. Recurrence poses a higher risk for sarcomatous transformation, increasing the risk for metastasis. Early and accurate diagnosis, coupled with appropriate management, is essential to minimize these risks. This study extended previous research by evaluating whether access to dermatology care …

Community Composition Of Antibiotic-Resistant Bacteria On The Mississippi Gulf Coast, Marisa Martin, Colin Jackson

Honors Theses

The Mississippi Gulf Coast is an important resource for transportation, economic development, and recreation. Given its economic and cultural importance, it is crucial to maintain clean and safe conditions along the coast for public health, but other than routine beach monitoring, few studies have examined microbial contamination of coastal waters in this region. This study aimed to determine the quantity, composition, and distribution of bacteria resistant to six different antibiotics (Vancomycin, Kanamycin, Tetracycline, Ciprofloxacin, Erythromycin, or Amoxicillin) in seawater at seven public beaches along the Mississippi Gulf Coast. No bacteria resistant to Ciprofloxacin were detected, and bacteria resistant to Kanamycin …

Clinical Outcomes Of A Non-Diffractive Extended Depth Of Focus Intraocular Lens In Post-Refractive Eyes, Collin Olevson, John P. Berdahl, Tanner J. Ferguson

Scholarship Pathways Program

Clinical outcomes of a non-diffractive extended depth of focus intraocular lens in post-refractive eyes

 Collin Olevson, MD¹ | John Berdahl, MD^1,2 and Tanner Ferguson, MD^1,2

¹University of South Dakota Sanford School of Medicine, Vermillion, SD

²Vance Thompson Vision, Sioux Falls, SD

Introduction: Eyes with prior corneal refractive surgery (i.e laser-assisted in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK)) pose challenges during cataract surgery due to altered corneal curvature. The AcrySof IQ Vivity intraocular lens (IOL) is a non-diffractive extended depth-of-focus (EDOF) IOL designed to provide a broader range of vision. Limited data exists on its …