Digital Commons Network^™

Staff Education To Reduce The Incidence Of Pressure Injury In Medical-Surgical Inpatients, Francis Omelu

Walden Dissertations and Doctoral Studies

No abstract provided.

An Emotional Intelligence Staff Education Program For Patient-Aligned Care Team (Pact) Members, Linda Rogers

Walden Dissertations and Doctoral Studies

No abstract provided.

Lessons Learned In Providing Infant And Early Childhood Mental Health Consultation During The Covid-19 Pandemic, Rashele Wade

Journal of Global Awareness

Access to quality childcare is a protective factor from lifelong issues such as school failure, school drop-out, and incarceration. Conversely, preschool suspension and expulsion are significant risk factors. Evidence-based interventions, such as Infant and Early Childhood Mental Health Consultation, aim to reduce and eliminate the incidence of preschool suspensions and expulsions. The COVID-19 pandemic disrupted access to quality childcare for many children across the country and globally. This study utilized a qualitative action research approach and generic qualitative inquiry to examine the research question, “How can we improve Infant and Early Childhood Mental Health Consultation through lessons learned during the …

Improving Nursing Compliance With Pressure Injury Prevention In Postoperative Patients In The Cardiovascular Intensive Care Unit, Chingyi Lam

Doctor of Nursing Practice Final Project Abstract

Pressure injuries acquired in the hospital continue to be a major concern in patient safety among critically ill populations. The purpose of the quality improvement project was to improve nursing compliance with pressure injury prevention strategies among postoperative patients in a cardiovascular intensive care unit (CVICU). Patients who undergo cardiovascular surgery are at a high risk of developing pressure injuries due to immobility, sedation, vasopressors, and prolonged positioning on their backs. The quality improvement project was carried out in a 37-bed CVICU using the Institute for Healthcare Improvement (IHI) Model for Improvement and Plan–Do–Study–Act (PDSA) cycles. Data on nursing repositioning …

Bridging Images And Language In Radiology: A Comprehensive Prisma Systematic Review Of Transformer Vision-Language Models And Clinical Readiness, Mohammad T. Khasawneh Dr., Sadaf Tabatabaee

Systems Science and Industrial Engineering Student Scholarship

Transformer vision-language models (VLMs) promise end-to-end automation of radiology reporting and related multimodal tasks. However, evidence remains fragmented across datasets, architectures, evaluation practices, and levels of clinical validation, limiting fair comparison and safe translation into practice. Following PRISMA 2020/PRISMA-S, search engines including PubMed, IEEE Xplore, Web of Science, and Google Scholar were systematically searched for peer-reviewed, English-language studies published between 2019 and 2025 that used paired radiology images and free-text reports. Dual reviewers screened records and extracted data using a locked schema covering datasets, modalities, architectures, training objectives, evaluation metrics, and indicators of clinical readiness. Free-text model descriptions were normalized …

Brain Age Prediction In Generalized Anxiety Disorder Using A Convolutional Neural Network, Corey Richier, André Zugman, Anita Harrewijn, Elise M Cardinale, Parmis Khosravi, Moji Aghajani, Willem B Bruin, Kevin Hilbert, Narcis Cardoner, Daniel Porta-Casteràs, Marta Cano, Savannah Gosnell, Ramiro Salas, Andrea P Jackowski, Pedro M Pan, Giovanni A Salum, Karina S Blair, James R Blair, Mohammed R Milad, Katie L Burkhouse, K Luan Phan, Heidi K Schroeder, Jeffrey R Strawn, Katja Beesdo-Baum, Neda Jahanshad, Sophia I Thomopoulos, Jared A Nielsen, Jordan W Smoller, Jair C Soares, Benson Mwangi, Mon-Ju Wu, Giovana B Zunta-Soares, Michal Assaf, Gretchen J Diefenbach, Paolo Brambilla, Eleonora Maggioni, David Hofmann, Thomas Straube, Carmen Andreescu, Rebecca B Price, Gisele G Manfro, Federica Agosta, Elisa Canu, Camilla Cividini, Massimo Filippi, Milutin Kostić, Ana Munjiza Jovanovic, Brenda Benson, Gabrielle F Freitag, Ellen Leibenluft, Grace V Ringlein, Kathryn Werwath, Hannah Zwiebel, Hans J Grabe, Sandra Van Der Auwera, Katharina Wittfeld, Henry Völzke, Robin Bülow, Nicholas L Balderston, Monique Ernst, Lilianne R Mujica-Parodi, Helena Van Nieuwenhuizen, Hugo D Critchley, Elena Makovac, Matteo Mancini, Frances Meeten, Cristina Ottaviani, Gregory A Fonzo, Martin P Paulus, Murray B Stein, Raquel E Gur, Ruben C Gur, Antonia N Kaczkurkin, Bart Larsen, Theodore D Satterthwaite, Jennifer Harper, Michael T Perino, Chad M Sylvester, Qiongru Yu, Patrick Mcclure, Francisco Pereira, Ulrike Lueken, Dick J Veltman, Paul M Thompson, Nynke A Groenewold, Janna Marie Bas-Hoogendam, Dan J Stein, Nic J A Van Der Wee, Anderson M Winkler, Daniel S Pine, Chelsea K Sawyers

Faculty, Staff and Student Publications

Higher predicted brain age difference has been associated with several psychiatric disorders. Generalized anxiety disorder (GAD) is associated with markers of accelerated aging. In this study, we determined brain predicted age difference (PAD) in individuals with GAD and healthy controls (HC) as well as group differences in PAD variability using voxel-wise structural MRI. The training dataset included 3511 controls, and the testing dataset included 1595 individuals with GAD and 4552 HC from the ENIGMA-Anxiety GAD Working Group. A convolutional neural network model using four input modalities per subject and a model ensemble approach was used to predict brain age. The …

Updated Trends In The Global Prevalence And Burden Of Mental Disorders, 1990–2023: A Systematic Analysis For The Global Burden Of Disease Study 2023, Damian F. Santomauro, Paul Anthony Miller, Jamileh Shadid, Sarah Wulf Hanson, Anh Vo, Darius Jake Roy, Hailey Hagins, Ana M. Mantilla Herrera, James G. Scott, Holly E. Erskine, John J. Mcgrath, Hasan Aalruz, Hedayat Abbastabar, Nadin M.I. Abdel Razeq, Ahmed Abdelrahman Abdelgalil, Ali Abdolizadeh, Deldar Morad Abdulah, Abisola Esther Abdulmalik, Meklit Girma Abebe, Mesfin Abebe, Habtamu Abebe Getahun, Roberto Ariel Abeldaño Zuñiga, Olifan Zewdie Abil, Richard Gyan Aboagye, Shady Abohashem, Abdullahi Tunde Aborode, Moaz Elsayed Abouelmagd, Mohammad T. Abuawwad

All Works

Background The 2023 iteration of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) estimated prevalence, incidence, and health burden for 375 diseases and injuries, including 12 mental disorders. We assess past, current, and emerging trends in the prevalence and burden of mental disorders across sexes and age groups, for 21 regions, 204 countries and territories, and by Socio-demographic Index (SDI) quintile, from 1990 to 2023. Methods Mental disorders included in GBD 2023 were anxiety disorders, major depressive disorder, dysthymia, bipolar disorder, schizophrenia, autism spectrum disorders, conduct disorder, attention-deficit hyperactivity disorder, anorexia nervosa, bulimia nervosa, idiopathic developmental intellectual …

Exploring Clinical Ladder Program Participation Among Operating Room Nurses, Camille Sistoso-Lorenzana

Doctoral Projects

Continuous professional development among nurses is vital, yet not all nurses embark on this career journey. The Clinical Ladder Program (CLP) is a retention strategy among various health institutions to retain talent and improve nurses' satisfaction, but this plan is unappealing or indifferent to some nurses. While the CLP is a motivation tool for nurses to focus on clinical expertise in bedside care (Riley et al., 2009), and resources are available to increase a nurse's chances of successfully advancing the ladder, participation in and perspectives on the CLP remain unknown, especially among operating room nurses. This project is guided by …

Floaters, Kyle Gyumin Dong

Masters Theses

The eye is often regarded as the primary sensory organ of the human body, and the ocular system as our most reliable means of perceiving the world.

With vision, we travel across vast distances through telescopes to expand our knowledge of the observable universe and peer into the hidden world of atoms through microscopes. At the same time, we seek divinity from apparitions in the clouds, broaden the range of colors visible under closed eyelids, and catch a brief glimpse of the future in clairvoyant dreams.

My photographic practice oscillates across this spectrum. Between reason and intuition, between the measurable …

Improving Nurse Competency In Vascular Occlusion Prevention And Management, Arielle Victoria Madayag

Doctor of Nursing Practice Final Manuscripts

Background: Vascular occlusion is a rare, but serious complication of dermal filler injections that can lead to severe adverse outcomes, including tissue necrosis and vision loss. As the demand for minimally invasive cosmetic procedures increases, proper nurse education and preparedness in managing vascular complications remain essential to ensuring patient safety.

Purpose: To evaluate the effectiveness of a structured educational session combined with simulation-based training on nurses’ knowledge, confidence, and clinical competency in recognizing and managing vascular occlusion associated with dermal filler injections.

Methods: A pretest-posttest educational intervention design was used. Four registered nurses (N=4) employed at a medical spa participated …

Intimate Partner Violence Screening And Awareness Pilot Project, Eleasha P. Partner

Doctor of Nursing Practice (DNP) Projects

Background: In the United States, one in four women experiences intimate partner violence (IPV), highlighting the critical need for improved screening and intervention within the healthcare system. Routine visits in healthcare settings present a significant opportunity for healthcare providers to identify and address IPV.

Local Problem: A primary care family practice clinic in San Leandro, California , currently lacks a standardized evidence-based screening toolkit for IPV.  The absence of such a toolkit creates a gap in practice, leaving patients at risk of undiagnosed IPV and its related consequences.  To address this gap, there is a pressing need for the development …

Foveate, Dahlia Aggarwal

Masters Theses

This thesis investigates how textiles can unsettle visual assumptions, encouraging a perceptual shift. Through weaving, upholstery, and spatial installation, the work stages a tension between what a surface appears to be and how it is encountered by the body. Through woven pattern, tactile texture, and trompe l’oeil textile surfaces, perception is something negotiated rather than fixed: the eye anticipates one reality while the hand discovers another.

Drawing on a range of sensations gathered from observing landscape formations and textures, it translates enduring scale and material qualities into an interior landscape of woven surfaces and textile-based furniture. Rather than serving as …

Accelerating Wound Healing Rates With Cucurbita Pepo Leaf Extract Loaded Electrospun Poly(Methyl Methacrylate)/Halloysite/Chitosan/ Caco₃ Composite Nanofibers Through In Vitro And In Vivo Assessments, Samar A. Salim

Nanotechnology Research Centre

Cucurbita pepo leaf extract (CPE) was incorporated into electrospun poly(methyl methacrylate)/ halloysite/chitosan/ CaCO₃ (PMMA/Hal/CS/CaCO₃) composite nanofibers to develop a novel biomaterial for accelerating wound healing rates. The different nanofibrous scaffolds were successfully fabricated and characterized through scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). SEM analysis revealed uniform, smooth nanofibers, while FTIR and XRD confirmed the integration of CPE into nanofiber matrix, indicating an amorphous structure and effective dispersion of the extract. In vitro agar well-diffusion and antibiofilm assays revealed that the optimized formulation exhibited potent antimicrobial activity against wound-associated pathogens. The nanofibers composite based on …

The Effects Of Asymmetric Cervical Muscle Fatigue On Cervical Proprioception, Stepping, And Standing Postural Sway, Maryam Homafar

LSU Master's Theses

Background: The cervical spine contributes critically to proprioception and postural control through its dense mechanoreceptor population. The acute effects of asymmetrical cervical muscle fatigue on proprioception, gait, and balance remain understudied, especially considering its widespread occurrence in multiple populations.

Objective: To investigate the acute effects of asymmetrical cervical muscle fatigue on cervical proprioception, stepping ability, and standing postural sway in healthy young adults.

Methods: Eighteen of 25 healthy participants, who met the inclusion criterion of baseline cervical joint position error (CJPE) below 4.5° for left and right rotational directions, completed pre-fatigue and post-fatigue assessments with eyes closed, including CJPE test, …

Soft Power, Arab Media And Sports Mega Events: Coverage Of Fifa 2022 And Lessons For Future Arab Hosting, Lynne Kennedy, Maaira Shahbaz, Ala Al Rajabi

All Works

Sport mega-events (SMEs) increasingly transcend athletic competition, functioning as strategic instruments for national identity formation, statecraft, and soft power projection. This dynamic is particularly pronounced in the Gulf, where Qatar’s successful hosting reignited regional rivalries and attracted unprecedented global scrutiny. While existing scholars have extensively examined Western media portrayals of SMEs, a notable gap remains for academic engagement with Gulf media. Dismissed as state-controlled and analytically lacking, we contend that such media offer a rich site for exploring how small states use media as soft power, to construct and contest legitimacy, identity, and global influence. This analysis suggests how state-aligned …

Staff Education To Emergency Department Professional Nurses, Florence Chukwuneke Chukwuneke

Walden Dissertations and Doctoral Studies

No abstract provided.

Yoga And Young Children, Jayapriya Ranganathan, Cynthia F Dicarlo

Spark! Innovations in Early Childhood Education: A Research-to-Practice Journal for Educators

Abstract:

This article examines the role of yoga as an effective pedagogical tool to support social-emotional learning (SEL) and physical development in early childhood education settings. Grounded in current understandings of mindfulness and executive functioning, the integration of yoga practices—such as breathing exercises, meditation, and developmentally appropriate postures—can promote self-regulation, attention, and emotional resilience in young children. Drawing on classroom-based observations from a toddler program, the article outlines practical strategies for incorporating yoga into daily routines, emphasizing accessibility, consistency, and engagement through imaginative play and storytelling. The findings suggest that regular yoga practice fosters a calm, focused learning environment and …

Ghastly Growths And Bone Chilling Cases Pediatric Tumor Diagnosis Demystified, Alexander Aly Restum, Arif Musa

Medical Student Research Symposium

Background:

Pediatric skeletal tumors range from benign to malignant and require multimodal imaging for accurate diagnosis. Recognizing key features enables early detection, guides management, identifies underlying syndromes, and improves outcomes. This presentation provides an educational overview of pediatric tumor evaluation.

Methods:
We conducted a focused review of peer-reviewed literature and representative pediatric imaging studies to outline the radiologic characteristics of common benign and malignant bone tumors in children. Core imaging patterns, diagnostic challenges, and modality-specific advantages were synthesized to create a practical interpretive framework for radiologists.

Results:
The reviewed literature and imaging demonstrated consistent defining features across pediatric bone tumors. …

Enhancing Medical Student Readiness To Provide Care For Youth Involved In The Juvenile Justice System, Tara Rahmani, Noah Kos, Kristen Bartow, Sospeter Machani, Jonathan Hakim, Elyse Vanderwoude, Anastasia Sahu, Abigail Schuch, Jennifer Mendez Ph.D, Laura Benjamins Md,Mph, Faap, Aahivms, Anupama Devara, Adeel Khan D.O.

Medical Student Research Symposium

Title

Enhancing Medical Student Readiness to Provide Care for Youth Involved in the Juvenile Justice System

Authors

Tara Rahmani, Noah Kos, Kristen Bartow, Sospeter Machani, Jonathan Hakim, Elyse VanderWoude, Anastasia Sahu, Abigail Schuch, Jennifer Mendez, Ph.D, Laura Benjamins, MD, MPH, Anupama, Devara, MD, Adeel Khan, DO

Background

Youth involved in the juvenile justice system face profound health inequities with higher rates of mental health needs, substance use, and trauma. Despite this, medical students rarely receive preparation to work in correctional health settings. Prior research has shown that youth in detention often exhibit behaviors shaped by past trauma and neglect, which …

Age-Dependent Physiologic Differences And Predicted Survival In Pediatric Trauma Patients, Christian Hudson-Bradford Md, Laura Elizabeth Sansoterra, Elika Ridelman Phd, Samantha Carranza, Megan Zacarias, Christina Shanti Md

Medical Student Research Symposium

Background:
Pediatric trauma patients exhibit outcomes not fully captured by adult-derived prediction models. This study examined clinical measures associated with predicted survival in this population.

Methods:
A retrospective review was conducted at a level one pediatric trauma center for patients ≤12 years old admitted between July 2015 and October 2024 with major trauma (Injury Severity Score (ISS) >15). A total of 406 eligible cases were categorized by Trauma and Injury Severity Score (TRISS) survival probability as preventable (>0.50), possibly preventable (0.25–0.50), or non-preventable (< 0.25). Demographic, physiologic, and management variables were compared using Kruskal–Wallis and chi-square tests with Bonferroni correction.

Results:
Most patients were classified as preventable (83%), followed by possibly preventable (9.8%) and non-preventable …

In-Use Stability And Device Compatibility Define Clinically Actionable Handling Limits For A Gmp-Produced Attenuated Listeria Monocytogenes Vaccine Expressing Gucy2c, Jagmohan Singh, Taranjot Johar, Vannessa Scully, Scott A. Waldman, Babar Bashir, Adam E. Snook

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Background: Live-attenuated Listeria monocytogenes (Lm) vectors are a clinically validated cancer immunotherapy platform, but translation requires reproducible, clinically realistic workflows for dose preparation and infusion. For live bacterial products, in-use stability and device compatibility can drive dose variability through adsorption, settling, and device losses. Methods: We developed and GMP-manufactured an attenuated Lm vaccine expressing human GUCY2C (Lm-GUCY2C) and performed translational characterization, including construct verification and immunogenicity readouts, and defined the administration-focused in-use stability and device compatibility. Post-thaw stability was assessed in primary cryovials and during preparation and delivery from 250 mL saline infusion bags using standard clinical devices (syringes/needles, filter-free …

Evidence-Based Approaches To Managing Adolescent Aggression, April Dade

Walden Dissertations and Doctoral Studies

No abstract provided.

Hiv/Aids-Related Awareness And Misconceptions Among Grade 10 Students In Muttrah Wilayat, Muscat, Oman: A Descriptive, Cross-Sectional Study, Rahma Abdullah Al Riyami, Balqees Ahmed Al -Maawali, Nabila Hamood Al Wahaibi, Mariam Rashid Al Rashdi, Fatma Ahmed Al Hinai

Sultan Qaboos University Medical Journal

Objectives: Despite Oman having a low HIV prevalence, stigma and lack of knowledge among young people may hinder prevention efforts. This study aimed to assess HIV/AIDS-related knowledge and misconceptions among Grade 10 students in Muttrah wilayat in Oman. Methods: This cross-sectional study was conducted in February 2025 and included Grade 10 students from 4 governmental schools in Muttrah selected via proportional stratified sampling. The sample size was calculated depending on the number of students in Grade 10. Data collection was performed during face-to-face interviews using a validated Arabic-language questionnaire. Results: A total of 271 Grade 10 students were included in …

Staff Education To Standardize Suicide Risk Assessment Across All Patients, Ebiere Erukanure

Walden Dissertations and Doctoral Studies

No abstract provided.

Circulating Metabolites Associated With Protection Against Mycobacterium Tuberculosis Infection And Inhibition Of Mycobacterial Growth, Todia P Setiabudiawan, Lika Apriani, Julian Avila-Pacheco, Edwin Ardiansyah, Vinod Kumar, Bachti Alisjahbana, Ayesha J Verrall, Andrew R Dinardo, Agnes R Indrati, Vera P Mourits, L Charlotte J De Bree, Simone J C F M Moorlag, Clary B Clish, Leo A B Joosten, Arjan Van Laarhoven, Krista E Van Meijgaarden, Mihai G Netea, Simone A Joosten, Valerie A C M Koeken, Philip C Hill, Reinout Van Crevel

Faculty, Staff and Students Publications

A significant proportion of individuals who are heavily exposed to infectious tuberculosis patients do not acquire Mycobacterium tuberculosis (Mtb) infection, as detected by an interferon gamma release assay (IGRA). We examined circulating metabolite profiles and metabolic genotypes in 199 heavily exposed IGRA-negative tuberculosis household contacts in Indonesia. Based on differentially abundant metabolites, activity of several pathways including arachidonic acid, arginine and proline, glutathione, and tryptophan metabolism, correlated with a negative IGRA at three months. SNPs near PRODH (involved in arginine and proline metabolism) were associated with circulating proline concentrations and persistently negative IGRA results, while SNPstudys near AFMID (involved in …

Improving Hyaluronic Acid Filler Safety Through A Structured, Evidence-Based Training Program: A Dnp Educational Initiative, Carlos Sandoval Madrigal

Doctoral Projects

The rapid growth of aesthetic medicine, particularly the use of hyaluronic acid (HA) dermal fillers, has outpaced the development of standardized educational pathways for Health Care Providers (HCPs), contributing to a wide variability in clinical practice and increased risk of adverse events. This Doctor of Nursing Practice (DNP) project aimed to evaluate the effectiveness of a structured, evidence-based educational intervention designed to improve provider knowledge and confidence in the prevention and management of HA filler complications. The intervention was developed using the 10-Point Plan framework and evaluated using the Kirkpatrick Model Levels 1 (Reaction) and 2 (Learning). A quasi-experimental, one-group …

Early Chemical Markers Of Spoilage In Thermally Processed Tomato Paste: A Rapid Approach For Shelf-Stable Foods, Hussein Ali Shaghati, Rawia Mahmood Yousif

Al-Nisour Journal for Medical Sciences

This study aims to reduce the incubation period (commercial sterility test) of tomato paste cans before the bacteriological inspection in quality control laboratories. 62 cans of tomato paste were incubated under temperatures (mesophilic 25,37°C and thermophilic 55°C) to accelerate potential spoilage. Chemical indicators(pH, titratable acidity, and lactic acid) and microbial indicators (Total plate count and yeast/molds) were monitored daily to identify the earliest reliable spoilage signals. Incubation at elevated temperatures accelerated acid buildup. D+L lactic acid levels measured using a rapid enzyme assay increased with titratable acidity, while pH decreased. Meanwhile, total platelet counts remained at very low levels, while …

Environmental Impact Of Benzo[A]Anthracene Exposure On Liver Biomarkers And Covid-19 Severity: Evaluation Of Combined Clinical And Molecular Modeling, Osamah Alkilidar, Hayder G. Jawad, Hasan K. Nimr

Al-Nisour Journal for Medical Sciences

This study aimed to evaluate the relationship between exposure to environmental pollutants, particularly benzo[a]anthracins (BaA), and the severity of the inflammatory response and liver dysfunction in COVID-19 patients, using a combination of statistical analysis and molecular modeling. Molecular docking studies revealed stable and robust interactions between benzo[a]anthracins and cytochrome P450 (CYP450) enzymes, suggesting that these interactions may contribute to increased oxidative stress and hepatocyte damage. The statistical analysis included 70 COVID-19 patients, stratified by benzo[a] anthracene exposure. The results showed statistically significant associations between exposure to this pollutant and elevated C-reactive protein (CRP) levels, as well as a significant increase …

Predicting The Risk Of Diabetes Using Machine Learning Algorithms, Noor Ismail Ibrahim, Jamal Kamil Alrudaini, Hytham Falih Hassan, Sahar Faeq Jaafar

Al-Nisour Journal for Medical Sciences

Diabetes is a chronic disorder that many people suffer from. This disease develops when the blood glucose level is high. Serious side effects, such as harm to the heart, kidneys, eyes, and other organs may result from diabetes neglected treatment. Diabetes has numerous causes, including aging, obesity, inactivity, genetics, poor food and lifestyle choices. Early identification of this illness helps lessen its negative consequences. There are many traditional methods for predicting this disease, but they are expensive. Early prediction of diabetes benefits all those at risk by providing early treatment. With the advancement of healthcare technology, machine learning algorithms can …

Allopurinol Beyond Hyperuricemia: A Multifaceted Therapeutic Agent With Expanding Clinical, Safa Khaldoon, Emad Yousif, Khawla A. Kasar, Hazim F. Abbas

Al-Nisour Journal for Medical Sciences

Allopurinol is a well-established xanthine oxidase inhibitor widely used in the management of hyperuricemia, gout, tumor lysis syndrome, and uric acid nephrolithiasis. This review provides a comprehensive overview of its pharmacology, mechanism of action, pharmacokinetics, clinical efficacy, safety profile, and emerging insights from recent clinical and translational studies. Despite being in clinical use for over five decades, allopurinol remains the first-line urate-lowering therapy worldwide due to its proven efficacy, favorable safety profile, and cost-effectiveness. Beyond its classical role in inhibiting xanthine oxidoreductase, increasing evidence highlights additional therapeutic effects, including antioxidant and anti-inflammatory activities. The structural similarity of allopurinol to purine …