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Articles 1291 - 1320 of 103421
Full-Text Articles in Entire DC Network
Epidemiology And Outcomes Of Geriatric Trauma At Uab, Lindy Reynolds
Epidemiology And Outcomes Of Geriatric Trauma At Uab, Lindy Reynolds
ETDs from 2020-2029
Adults over the age of 65 are the fastest growing portion of the population and account for a growing percentage of the trauma patient volume at trauma centers around the country. Older adults experience longer length of stays, higher mortality and complication rates than their younger counterparts. As a result, there has recently been an increased focus on models of geriatric trauma care, one of which is the addition of geriatric medicine consults for older trauma patients. The primary objectives of this dissertation were to examine the effect of the consult policy on outcomes using an interrupted time series approach, …
A Retrospective Analysis Of Dental Needs Identified By Intraoral Videography In Elderly Patients With Mild To Moderate Dementia In Long-Term Care Facilities: Feasibility Of A Novel Screening Mechanism For Oral Health, Kevin Hahn
ETDs from 2020-2029
This retrospective analysis explores the viability of employing intraoral videography to identify dental needs among long-term care (LTC) facility residents with cognitive impairment and/or mild to moderate dementia. Inadequate oral hygiene in these individuals can lead to dental plaque buildup, oral dysbiosis, gingivitis, dental caries, and periodontitis. Such conditions can impact both oral and systemic health. However, delivering oral hygiene in LTC facilities faces challenges due to care-resistant behavior triggered during mouth care. And many individuals in residential LTC facilities do not have access to dental care outside of severe emergencies due to cost, reimbursement patterns, lack of access to …
Individual Responsibility And The Limits Of U.S. Dietary Guidelines: Addressing Ultra-Processed Food Consumption Through Structural Policy, Malika Al Kattan, Lynne Alexandra Kennedy
Individual Responsibility And The Limits Of U.S. Dietary Guidelines: Addressing Ultra-Processed Food Consumption Through Structural Policy, Malika Al Kattan, Lynne Alexandra Kennedy
All Works
No abstract provided.
Intrathecal (G4c2)149 Delivery In C9orf72-Deficient Mice Yields Mild Motor Dysfunction And Als/Ftd Pathological Hallmarks, Katelyn Russell, Amelia Shahrabi, Suleyman Akerman, Matthew D. Byrne, Jeffrey Rothstein, Davide Trotti, Brigid Jensen, Aaron Haeusler
Intrathecal (G4c2)149 Delivery In C9orf72-Deficient Mice Yields Mild Motor Dysfunction And Als/Ftd Pathological Hallmarks, Katelyn Russell, Amelia Shahrabi, Suleyman Akerman, Matthew D. Byrne, Jeffrey Rothstein, Davide Trotti, Brigid Jensen, Aaron Haeusler
Farber Institute for Neuroscience Faculty Papers
A repeat expansion in C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), yet existing mouse models incompletely engage spinal regions implicated in disease. Here, an adeno-associated virus encoding (G4C2)149 repeats was delivered via neonatal intrathecal injection, achieving widespread CNS expression with robust spinal cord targeting. This approach was applied to mice with graded loss of endogenous C9orf72 to interrogate both gain- and loss-of-function mechanisms. Longitudinal motor, behavioral, and pathological analyses revealed that repeat expression primarily drives mild, progressive muscle weakness, whereas coordination deficits were largely genotype dependent. Subtle gait abnormalities and hyperactivity …
Centralized Review Of Alzheimer's Disease And Related Dementias Biomedical Repositories And Computational Methods, Johaan Kathilankal, Kewei Chen, Chen Zhao, Lingtao Chen, Seyedamin Pouriyeh, Zongxing Xie, Yixin Xie
Centralized Review Of Alzheimer's Disease And Related Dementias Biomedical Repositories And Computational Methods, Johaan Kathilankal, Kewei Chen, Chen Zhao, Lingtao Chen, Seyedamin Pouriyeh, Zongxing Xie, Yixin Xie
Faculty Articles
lzheimer’s disease and related dementias (ADRD) are neurodegenerative conditions characterized by progressive cognitive and functional decline. AD pathology is associated with extracellular amyloid-β plaques, intracellular tau neurofibrillary tangles, synaptic dysfunction, and neuronal loss. AD accounts for approximately 60–80% of dementia cases globally. In 2022, AD was the seventh leading cause of death in the United States, and the number of Americans aged 65 and older living with Alzheimer’s dementia is projected to increase substantially by 2060. Despite decades of research, AD/ADRD data resources remain fragmented across clinical, imaging, genetic, genomic, and therapeutic domains. This paper addresses that gap by providing …
When “Mild” Isn’T Minor: Return-To-Work Challenges In Post-Stroke Mild Aphasia, Maya Berro
When “Mild” Isn’T Minor: Return-To-Work Challenges In Post-Stroke Mild Aphasia, Maya Berro
USF Tampa Graduate Theses and Dissertations
Return-to-work (RTW) is an important aspect of social participation and quality of life following stroke. However, limited research has explored the experiences of individuals with mild aphasia in the RTW process. This purpose of this qualitative study was to explore how individuals with post-stroke mild aphasia perceive their ability to RTW and identify factors that influence this process. Ten adults with mild or very mild aphasia participated in individual semi- structured interviews conducted via Microsoft Teams. Interview transcripts were analyzed using inductive thematic analysis. Three major themes emerged: (1) Barriers to RTW, (2) Facilitators to RTW, and (3) Perceptions of …
Independent Living Skills For The Aging Population Of Adults With Disabilities, Sara K. Fetter Otd, Otr, Jennifer L. Martin Otd, Otr, Cht, Clt, Michele L. Mccarroll Phd, Faacvpr, Acsm-Ccep, Ccrp, Lssbb
Independent Living Skills For The Aging Population Of Adults With Disabilities, Sara K. Fetter Otd, Otr, Jennifer L. Martin Otd, Otr, Cht, Clt, Michele L. Mccarroll Phd, Faacvpr, Acsm-Ccep, Ccrp, Lssbb
Developmental Disabilities Network Journal
Adults with intellectual disability (ID) are living longer and increasingly outlive family caregivers. Strengthening independent living and vocational skills has therefore become a critical public-health priority. Occupational therapy (OT) can address this need through person-centered, community-based programming. This paper describes the co-design, delivery, and preliminary outcomes of a short occupation-based curriculum intended to enhance autonomy and work readiness in aging adults with ID. In partnership with a Dallas, Texas nonprofit, the authors conducted a needs assessment and created an 8-session course rooted in the Independent Living Model and the Occupational Competence Model. The curriculum addressed four domains (physical health, financial …
Twenty-First-Century Readiness Of Thai Doctor Of Veterinary Medicine Curricula: A Documentary Analysis Using The Competency-Based Veterinary Education 2.0 Framework, Pongphol Pongthaisong, Manakant Intrakamhaeng
Twenty-First-Century Readiness Of Thai Doctor Of Veterinary Medicine Curricula: A Documentary Analysis Using The Competency-Based Veterinary Education 2.0 Framework, Pongphol Pongthaisong, Manakant Intrakamhaeng
The Thai Journal of Veterinary Medicine
Twenty-first-century veterinary practice demands graduates who combine clinical expertise with professional competencies including communication, financial literacy, evidence-based practice, and One Health awareness. Whether Thai Doctor of Veterinary Medicine (DVM) curricula systematically develop these competencies has not been evaluated across the full national cohort. This study assessed the 21st-century readiness of all 11 accredited Thai DVM programs using the Competency-Based Veterinary Education 2.0 (CBVE 2.0) framework (AAVMC Council, 2024). Program Learning Outcomes (PLOs) and course specifications from Thai Qualifications Framework curriculum specification documents (TQF-2; มคอ.2) were analyzed using deductive content analysis against all 9 CBVE 2.0 domains, with inter-rater reliability established …
Hiv Preexposure Prophylaxis (Prep) Satisfaction Amongst Female Sex Workers And Men Who Have Sex With Men In Cameroon, Zacheaus Zeh Akiy
Hiv Preexposure Prophylaxis (Prep) Satisfaction Amongst Female Sex Workers And Men Who Have Sex With Men In Cameroon, Zacheaus Zeh Akiy
Walden Dissertations and Doctoral Studies
No abstract provided.
Breaking Bread And Barriers: Interprofessional Strategies To Improve Mental And Nutritional Health In Family Caregivers, Candy Ratliff
Breaking Bread And Barriers: Interprofessional Strategies To Improve Mental And Nutritional Health In Family Caregivers, Candy Ratliff
The Journal of the Research Association of Minority Professors
Family caregivers provide essential unpaid support to individuals with chronic illness, disability, dementia, and age-related decline; however, caregiving responsibilities often place caregivers at increased risk for psychological, physical, nutritional, and social challenges. This literature review examines the mental health and nutritional implications of family caregiving and explores barriers that contribute to declining caregiver wellness. Findings reveal elevated rates of depression, anxiety, emotional exhaustion, social isolation, food insecurity, sleep disturbances, financial strain, and chronic stress among caregivers. The literature further highlights the interconnected relationship between mental health, nutrition, and overall quality of life. Given the multidimensional nature of caregiver burden, interprofessional …
Antimicrobial Resistance In Pediatric Infections: Current Status, Challenges, And Future Directions, Clare Dinh, Keykavous Parang
Antimicrobial Resistance In Pediatric Infections: Current Status, Challenges, And Future Directions, Clare Dinh, Keykavous Parang
Pharmacy Faculty Articles and Research
Background/Objectives: Antimicrobial resistance in pediatric infections presents a worsening global public health challenge, with antimicrobial resistance (AMR) accounting for more than one million deaths annually and disproportionately affecting children younger than 5 years of age. Neonates and critically ill children face heightened risk owing to immature immunity, frequent healthcare exposures, and limited therapeutic options. This review synthesizes evidence on the epidemiology, mechanisms of resistance, clinical outcomes, and management of AMR across the full pediatric age range. Methods: PubMed/MEDLINE and Google Scholar were searched for literature from 2014 to 2026 using terms covering antibiotic resistance, pediatric populations, and key …
Examining Diversity And Cultural Competency Within A Historically Black College And University (Hbcu) Public Health Curriculum, Alyce L. Hays, Yalanda M. Barner, Latarsha Michael
Examining Diversity And Cultural Competency Within A Historically Black College And University (Hbcu) Public Health Curriculum, Alyce L. Hays, Yalanda M. Barner, Latarsha Michael
The Journal of the Research Association of Minority Professors
Integrating diversity and cultural competency content into public health curricula is vital in preparing future health professionals to optimize health outcomes of all individuals; however, very few studies have examined whether diversity and cultural competencies are taught in public health curricula. Studies have consistently incorporated diversity, equity, and inclusion in education for healthcare professionals such as nursing, community health workers, health educators, etc. The purpose of this study was to assess the presence of course content diversity, equity, inclusion, cultural competency, or other related topics. A formative assessment approach utilizing a four-step evaluation process was used to review the inclusion …
Advancing Culturally Relevant Mindfulness In Public Health, Marcus Johnson, Candy Ratliff
Advancing Culturally Relevant Mindfulness In Public Health, Marcus Johnson, Candy Ratliff
The Journal of the Research Association of Minority Professors
Mindfulness-based interventions (MBIs) have gained significant traction in public health, education, and clinical settings due to their demonstrated benefits for stress reduction and psychological well-being. However, these interventions often originate from Eurocentric frameworks that insufficiently reflect the cultural, historical, and structural contexts of diverse and historically marginalized communities. This commentary proposes a Culturally Relevant Mindfulness (CRM) framework that centers the lived experiences, healing traditions, and epistemologies of underrepresented populations. Drawing on interdisciplinary literature and critiques of conventional mindfulness models, the article articulates four guiding principles of CRM: cultural identity affirmation, historical consciousness, ancestral integration, and community-centered practice. Rather than merely …
The Prevalence Of Dysphonia: A Comparison Of Indoor And Outdoor Athletic Coaches, Keelyn Peacock
The Prevalence Of Dysphonia: A Comparison Of Indoor And Outdoor Athletic Coaches, Keelyn Peacock
Student Theses and Dissertations
This investigation was conducted to assess the Prevalence of Dysphonia, while comparing indoor and outdoor athletic coaches. This investigation also looked at the prevalence of self-perceived vocal dysphonia symptoms within collegiate athletic coaches. This study was conducted by distributing a survey to the Division I athletic coaches in the state of Arkansas. The survey consisted of demographic questions, a questionnaire that explored the self-perceived vocal symptoms, clinician perspective vocal ratings, and acoustic parameters of voice recordings. The data collected revealed that there were vocal symptoms that were identified as an effect of occupational voice demand during the current season of …
Effectiveness Of Cadre Training In Improving Knowledge On The Completion Of The Elderly Health Book In Sidoarjo, Lilik Djuari, Sulistiawati Sulistiawati, Linda Dewanti, Muhammad Izhar Yuliantama, De Farras King, Minarni Wartiningsih
Effectiveness Of Cadre Training In Improving Knowledge On The Completion Of The Elderly Health Book In Sidoarjo, Lilik Djuari, Sulistiawati Sulistiawati, Linda Dewanti, Muhammad Izhar Yuliantama, De Farras King, Minarni Wartiningsih
Folia Medica Indonesiana
Primary healthcare in Indonesia faces challenges due to an ageing population since 2021. An elderly health book, published by Ministry of health, is an essential tool for recording, monitoring, and following up elderly health status. However, Health cadres have not yet fully understood how to fill in and use the book, resulting in suboptimal data quality. The objective of this study was to evaluate the effectiveness of cadre training to complete the Elderly Health Book (before and after training) in Sidoarjo Regency. A quasi-experimental study with a one-group pre-test and post-test design was conducted among 50 elderly health cadres which …
Nursing Staff Education On Transgender Patient Care In A Nursing Home, Cyril Shan Madera Tena
Nursing Staff Education On Transgender Patient Care In A Nursing Home, Cyril Shan Madera Tena
Walden Dissertations and Doctoral Studies
No abstract provided.
Oral Cancer Numerical Index (Ocni): Development And Validation Of A Cytology-Based Risk Assessment For Oral Lesions, Michael P Mcrae, Nadarajah Vigneswaran, Alexander Ross Kerr, Spencer W Redding, Martin H Thornhill, Craig Murdoch, Paul M Speight, Rachelle Wolk, Kritika S Rajsri, Pooja Gaikwad, Nancy Ruel, Nicolaos J Christodoulides, John T Mcdevitt
Oral Cancer Numerical Index (Ocni): Development And Validation Of A Cytology-Based Risk Assessment For Oral Lesions, Michael P Mcrae, Nadarajah Vigneswaran, Alexander Ross Kerr, Spencer W Redding, Martin H Thornhill, Craig Murdoch, Paul M Speight, Rachelle Wolk, Kritika S Rajsri, Pooja Gaikwad, Nancy Ruel, Nicolaos J Christodoulides, John T Mcdevitt
Faculty, Staff and Student Publications
Background/Objectives: Oral potentially malignant disorders (OPMDs) require accurate risk stratification to identify patients at the highest risk for severe oral epithelial dysplasia (OED) or oral squamous cell carcinoma (OSCC). We developed and internally validated the oral cancer numerical index (OCNI), a quantitative risk score derived from clinical features and deep learning-based brush cytology measurements.
Methods: This retrospective model development and internal validation study was conducted using data from the multicenter Grand Opportunity study. Prospectively recruited subjects with OPMD with complete data were divided at the subject level into a training set (n = 384) and a holdout test set …
The Prevalence Of Moral Injury Among Veterans Diagnosed With Post-Traumatic Stress Disorder (Ptsd): Analyses By Combat Exposure, Gender, Age Group, And Military Service, Carl B. Forkner
Doctoral Dissertations and Projects
The attacks on the United States on September 11, 2001, and the ensuing wars in Afghanistan and Iraq, heralded in a new concept affecting our combat and support military personnel. This concept is known today as moral injury. Military personnel were already familiar with post-traumatic stress disorder (PTSD), whether from personal experience or from reading and training on the subject, but no training addresses the prevalence or effects of moral injury. The term moral injury (MI) was first coined by psychiatrist Jonathan Shay and his colleagues based on feedback from military and veteran patients in 1998; however, it remains that …
Discourse Production And Its Relationship To Cognition In Mild Aphasia, Marcy D. Edwards
Discourse Production And Its Relationship To Cognition In Mild Aphasia, Marcy D. Edwards
USF Tampa Graduate Theses and Dissertations
Objective:Standardized assessments such as the Western Aphasia Battery-Revised do not reliably detect subtle language impairments in mild aphasia (Dalton & Richardson, 2015). Discourse tasks may provide a more sensitive measure of impairment. Although discourse tasks differ in cognitive demands (Kim & Kintz, 2024), variation in discourse performance across tasks and the influence of cognition remains unclear. Therefore, this study examined (1) whether discourse performance differs across different discourse elicitation tasks, and (2) the extent to which cognition influences discourse performance in individuals with mild aphasia.
Participants & Methods: Fifteen participants with mild aphasia participated (mean age = 62.7 years). Discourse …
Exploring Menstrual Cycle Experiences And Well-Being In Young Women With Type 1 Diabetes, Yolanda Rotzinger Ballesteros
Exploring Menstrual Cycle Experiences And Well-Being In Young Women With Type 1 Diabetes, Yolanda Rotzinger Ballesteros
USF Tampa Graduate Theses and Dissertations
Young women with type 1 diabetes (T1D) navigate complex physical, emotional, and social challenges, being at a higher risk for mental health concerns (e.g., depression), as well as physical (e.g., fatigue) and cognitive (e.g., focus) symptoms related to the management of their chronic health condition (Dantzer et al., 2003; Northam et al., 2005). About one-third of young women with T1D experience some form of menstrual dysfunction (Griffin et al., 1994; Schweiger et al., 2011), which is associated with lower quality of life across several domains, including the educational setting (Knox et al., 2015). Nevertheless, there is a gap in the …
Treatment Times For Rural And Urban Patients With Aneurysmal Subarachnoid Hemorrhage In A Provincial Hub-And-Spoke Network, Alexander D. Rebchuk, Hugh Mchugh, Michael A. Rizzuto, David Chen, Kelsey Cruz, Erik N. Vu, Peter A. Gooderham
Treatment Times For Rural And Urban Patients With Aneurysmal Subarachnoid Hemorrhage In A Provincial Hub-And-Spoke Network, Alexander D. Rebchuk, Hugh Mchugh, Michael A. Rizzuto, David Chen, Kelsey Cruz, Erik N. Vu, Peter A. Gooderham
Department of Neurosurgery Faculty Papers
BACKGROUND: Following aneurysmal subarachnoid hemorrhage (aSAH), aneurysm rebleeding leads to very poor clinical outcomes. Ruptured aneurysms must be urgently secured either by open microsurgery or endovascular techniques to prevent re-rupture. The objective of this study was to compare time-to-treatment and functional outcomes following aSAH between rural and urban patients treated at a quaternary neurosurgical centre with a large geographical catchment.
METHODS: We analyzed patients enrolled in the Vancouver Ruptured Aneurysm Database (VRAD) between December 2022 and September 2025. Demographic, clinical, radiographic, treatment and functional outcomes were compared between groups. Time from ictus-to-presentation, ictus-to-neurosurgical centre, ictus-to-treatment and transfer times were collected. …
The Effect Of Structured Prebriefing On Pre-Simulation Anxiety In Baccalaureate Nursing Students Participating In High-Fidelity Simulation: A Quantitative Quasi-Experimental Nonequivalent Pretest-Posttest Control Group Study, Laura D. Wade
Doctoral Dissertations and Projects
The purpose of this quantitative quasi-experimental nonequivalent pretest-posttest control group study was to examine the effect of structured prebriefing on pre-simulation state anxiety among baccalaureate nursing students participating in high-fidelity simulation (HFS) at a private faith-based university in the South-Central United States (U.S.). Simulation is widely used in nursing education; however, nursing students frequently experience elevated anxiety prior to simulation that may negatively influence learning and performance. Despite recognition of prebriefing as best practice in simulation-based education, limited quantitative research has examined the effect of structured prebriefing on pre-simulation anxiety. A convenience sample of 73 baccalaureate nursing students enrolled in …
Lived Experiences Of Polysubstance Use And Co-Occurring Mental Health Disorders: A Phenomenological Inquiry, Candee Dione Rillon
Lived Experiences Of Polysubstance Use And Co-Occurring Mental Health Disorders: A Phenomenological Inquiry, Candee Dione Rillon
Doctoral Dissertations and Projects
This phenomenological study explored the lived experiences of individuals with co-occurring substance use disorders (SUD) and mental health disorders (MHD), with particular attention to the transition into polysubstance use. The purpose of the study was to understand how individuals experience and make meaning of these co-occurring conditions and the factors influencing substance use patterns. Data were collected through semi-structured interviews with participants who reported both mental health challenges and substance use histories. Thematic analysis revealed that participants experienced SUD and MHD as deeply interconnected and mutually reinforcing, often functioning within a cyclical pattern of distress and temporary relief. Substance use …
Psycho-Behavioral And Psychosocial Factors Influencing Childhood Obesity In The United States, Nadia Ntori Nkansah
Psycho-Behavioral And Psychosocial Factors Influencing Childhood Obesity In The United States, Nadia Ntori Nkansah
Walden Dissertations and Doctoral Studies
No abstract provided.
Parental Perspectives On Their Children’S Mental Health Changes During And After The Covid-19 Pandemic In A Florida Community, Brianna Yumul
Parental Perspectives On Their Children’S Mental Health Changes During And After The Covid-19 Pandemic In A Florida Community, Brianna Yumul
Walden Dissertations and Doctoral Studies
No abstract provided.
Moving Beyond Occupational Health: Lessons From Implementing Integrated Worker Health Programs Among Informal Workers In Thailand, Orrapan Untimanon
Moving Beyond Occupational Health: Lessons From Implementing Integrated Worker Health Programs Among Informal Workers In Thailand, Orrapan Untimanon
Journal of Health Research
Background: This paper aims to present practical experiences and lessons learned from applying an integrated worker health approach among informal workers in Thailand. The approach draws on the concept of Total Worker Health (TWH) and is implemented through Primary Care Units (PCUs).
Methods: This is an invited commentary.
Results: Key steps included: (1) identification of occupational health (OH) services provided by PCUs; (2) development and refinement of an integrated worker health assessment tool based on TWH principles; (3) assessment and problem identification among informal workers, highlighting combined occupational and lifestyle-related risks; (4) design and implementation of integrated interventions; and (5) …
Anatomy And Function Of Vasopressin Receptor 1a-Expressing Neurons In The Limbic Thalamus, David Joseph Kahn
Anatomy And Function Of Vasopressin Receptor 1a-Expressing Neurons In The Limbic Thalamus, David Joseph Kahn
Theses and Dissertations
The vasopressin (Avp) system modulates social behavior through region-specific and sex-dependent mechanisms, yet the role of Avp receptor 1a (Avpr1a) signaling in the thalamus has remained largely unexplored. This dissertation examined the distribution and functional contributions of Avpr1a-expressing neurons across the mouse thalamus using a combination of genetic labeling, anatomical quantification, and chemogenetic manipulation. Mapping of Avpr1a-expressing neurons revealed a presence in most thalamic nuclei, with highest densities in the anterior thalamic nuclei and midline nuclei. Notably, Avpr1a-expressing neuron densities did not mirror previously described patterns of Avp innervation, and no sex differences in Avpr1a-expressing neuron density were observed. Chemogenetic …
If Pets Are Family: Pet Loss And The Need For Grief Equity In One Health, Michele L. Whitney
If Pets Are Family: Pet Loss And The Need For Grief Equity In One Health, Michele L. Whitney
Journal of One Health Systems
One Health frameworks increasingly recognize pets as integral to human health and well-being. However, these models often overlook the health and equity implications of pet loss. Culturally mediated grief experiences following pet bereavement represent a critical grief equity gap in One Health systems. Drawing on findings from a qualitative study of African American adults who experienced pet loss, along with existing literature, this Viewpoint highlights how pet loss is not only an emotional experience but also a socially structured one shaped by cultural norms, social recognition, and access to support. These dynamics contribute to inequities in how grief is experienced …
Comparison Of Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block And Thoracic Paravertebral Block For Postoperative Analgesia After Breast Surgery: A Prospective Randomized Noninferiority Trial, Mustafa Sirri Kotanoğlu, Musa Zengi̇n, Onur Küçük, Atakan Sezgi̇, İbrahi̇m Topcu, Aras Meti̇n, Zeynep Ersoy, Jüli̇de Ergi̇l
Comparison Of Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block And Thoracic Paravertebral Block For Postoperative Analgesia After Breast Surgery: A Prospective Randomized Noninferiority Trial, Mustafa Sirri Kotanoğlu, Musa Zengi̇n, Onur Küçük, Atakan Sezgi̇, İbrahi̇m Topcu, Aras Meti̇n, Zeynep Ersoy, Jüli̇de Ergi̇l
Turkish Journal of Medical Sciences
Background/aim: This noninferiority trial aimed to evaluate whether the serratus posterior superior intercostal plane block (SPSIPB) provides noninferior postoperative analgesia compared with the thoracic paravertebral block (TPVB) after unilateral mastectomy.
Materials and methods: This prospective, randomized, assessor-blinded, parallel-group noninferiority trial enrolled 60 female patients scheduled for elective unilateral mastectomy. Patients received either ultrasound-guided SPSIPB (n = 30) or TPVB (n = 30) with 30 mL of 0.25% bupivacaine before induction. The primary outcome was visual analogue scale (VAS) pain scores (0–100 mm) at rest and during coughing over 24 h. Noninferiority was assessed using the Hodges–Lehmann median difference with 95% …
Bridging The Methodological Gap In Multitrauma Literature: A Competency-Based Educational Framework And Clinical Appraisal Filter, Şaki̇r Hakan Aksu, Burcu Doğan, Merve Yazla
Bridging The Methodological Gap In Multitrauma Literature: A Competency-Based Educational Framework And Clinical Appraisal Filter, Şaki̇r Hakan Aksu, Burcu Doğan, Merve Yazla
Turkish Journal of Medical Sciences
Background/aim: The statistical complexity of contemporary multitrauma literature has increased considerably in recent years, which may pose challenges for clinicians seeking to interpret high-impact research and apply evidence-based practices. Characterizing this methodological landscape and exploring education-oriented approaches may help to improve the interpretability of the literature and support informed clinical decision-making.
Materials and methods: A cross-sectional analysis was conducted on the 100 most-cited multitrauma studies published in Science Citation Index Expanded journals indexed in the Web of Science database between January 2018 and November 2025. The statistical methods used in each article were categorized into the three competency levels of …