Digital Commons Network^™

Mitochondrial Genome Sequence Analysis: A Custom Bioinformatics Pipeline Substantially Improves Affymetrix Mitochip V2.0 Call Rate And Accuracy., Hongbo M Xie, Juan C Perin, Theodore G Schurr, Matthew C Dulik, Sergey I Zhadanov, Joseph A Baur, Michael P King, Emily Place, Colleen Clarke, Michael Grauer, Jonathan Schug, Avni Santani, Anthony Albano, Cecilia Kim, Vincent Procaccio, Hakon Hakonarson, Xiaowu Gai, Marni J Falk

Department of Biochemistry and Molecular Biology Faculty Papers

BACKGROUND: Mitochondrial genome sequence analysis is critical to the diagnostic evaluation of mitochondrial disease. Existing methodologies differ widely in throughput, complexity, cost efficiency, and sensitivity of heteroplasmy detection. Affymetrix MitoChip v2.0, which uses a sequencing-by-genotyping technology, allows potentially accurate and high-throughput sequencing of the entire human mitochondrial genome to be completed in a cost-effective fashion. However, the relatively low call rate achieved using existing software tools has limited the wide adoption of this platform for either clinical or research applications. Here, we report the design and development of a custom bioinformatics software pipeline that achieves a much improved call rate …

Persistence To An Associate Of Applied Science Registered Nurse Degree: The Impact Of Placing Into Developmental Education Courses On Student Success, Caroline Clark Rivera

Educational Leadership & Workforce Development Theses & Dissertations

Student retention and success in nursing school has gained favor in educational research due to an increasing shortage of Registered Nurses. The purpose of this study is to measure the impact of student placement recommendation into developmental education courses on persistence to an Associate of Applied Science Registered Nurse degree. Using ex post facto research methodology rooted in the retention theories of Tinto, Bean and Metzner, and Jeffreys, this study aims to measure the effect of high school diploma type, age, race/ethnicity, and pre-requisite courses on student placement recommendation in developmental education and persistence to an Associate of Applied Science …

Where Have All The Plant Foods Gone? The Search For Refined Dietary Reconstruction From Chinchorro Mummies, Karl J. Reinhard, Sara Le-Roy-Toren, Bernardo Arriaza

Karl Reinhard Publications

The Chinchorro cemeteries of northern Chile are the first graveyards of the Andes (Arriaza 1995, Schiappacasse & Niemeyer 1984). The excavation and analysis of Chinchorro mummies reveals the 'true character of the people'. The burials themselves are optimal for preservation of corpses, burial furniture, and aspects of ceremonies associated with the dead. The analysis of corporeal remains gradually clarifies the details of daily activities and status. Therefore, we feel that a holistic approach to mummy studies provides enormously fruitful paths to understanding the character of the ancient Chinchorro society.

Paleoepidemiology Of Intestinal Parasites And Lice In Pre-Columbian South America, Adauto Araujo, Karl Reinhard, Daniela Leles, Luciana Sianto, Alena M. Iñiguez, Martin Fugassa, Bernardo Arriaza, Nancy Orellana, Luis Fernando Ferreira

Karl Reinhard Publications

Some human parasites originated in prehominid ancestors in Africa. Nematode species, such as Enterobius vermicularis (pinworm), hookworms and Trichuris trichiura are shared by humans and other close phylogenetic primates (Pan and Gorilla), showing that they infected a common ancestor to this group. When humans migrated from Africa to other continents they carried these parasites wherever climate conditions allowed parasite transmission from host to host. Other parasites, however, were acquired throughout human biological and social evolutive history when new territories were occupied. Paleoparasitology data is a valuable source to recover emergence and disappearance of parasite infections through analysis of …

The Impact Of Company Grade Officer Self-Sacrificial Behavior On Subordinate Assessments Of Leader Charisma, Danjel Bout

Walden Dissertations and Doctoral Studies

Newly commissioned officers in the U.S. Army are taught to lead their soldiers from the front and to voluntarily make personal sacrifices in the service of the nation. Although this facet of military culture is seen as critical to the integrity of the force, there are few research studies describing the impact of leader self-sacrifice in the U.S. Army. Research evolving from the transformational leadership literature indicates that civilian leaders who engage in self-sacrificial behavior are viewed as more charismatic than their counterparts and that this perception is particularly pronounced in crisis situations. The current study extended this research to …

Beliefs, Concerns, And Methods Of Parents Raising Children Bilingually: A Study Of Hispanic Iowa Mothers Attempting To Maintain Heritage Language In Their Children, Briana Vera

Honors Program Theses

The purpose of my thesis was to discover more about parents who are raising their children to be English-Spanish bilingual, particularly their beliefs, concerns, and methods regarding this issue. I focused specifically on mothers in Iowa whose native language was Spanish and who had at least one child in the household between the ages of four and sixteen. A point of interest I focused on were the beliefs, concerns, and methods these mothers have and use to maintain their children‟s heritage language (Spanish) as the community language (English) becomes more prominent in their children‟s lives. This information is important for …

Radiological Population Monitoring: Views Of Public Health Professionals In The Southeastern United States, Gwendolyn N. Hudson

All ETDs from UAB

In the immediate aftermath of a radiological disaster, it is essential to rapidly screen the population to identify contaminated persons, those needing urgent medical treatment, and those requiring long-term follow-up. This process, known as "radiological population monitoring," is vital to reducing morbidity and mortality and effectively addressing people's health needs and concerns. Radiological population monitoring has become a significant new focus of attention and responsibility for government agencies in recent years, due in large part to growing concerns about the possibility of a terrorist attack involving radioactive materials. The primary responsibility for radiological population monitoring resides within state and local …

Three Dimensional Comparison Of Facial Morphology Of A Native Egyptian Population And A Native Brazilian Population, Ethan Larson

All ETDs from UAB

Introduction: The purpose of this study was to assess the use of three dimensional facial averages in determining facial morphological differences between a native adult Egyptian population and a native adult Brazilian population. Methods: Three- dimensional images were acquired through a commercially available stereo-photogrammetric camera system. The 3dMDfaceTM system was used to capture images from 186 subjects from two population groups (Egypt and Brazil). Each image was obtained as a facial mesh and orientated along a triangulated axis. All facial images were overlaid and superimposed, and a complex mathematical algorithm was performed to create a composite facial average of one …

First Elderly Client In Therapy: Factors That Influence Student Interest In Geropsychology, Cristina E. M. Filippelli

Antioch University Dissertations & Theses

In the coming decades, the elderly population in United States (U.S) is expected to grow significantly (U.S. Bureau of the Census, 1996). Consequently, the number of older individuals seeking mental health services will be greater than at any other time in the history of the U.S. The field of clinical psychology, however, is unable to meet the mental health needs of the current elderly population, and this gap is expected to widen in coming years. There is an ongoing discussion within the field of professional psychology as to how to train more clinicians to work with the elderly population (Gatz …

Effectiveness Of Artemether-Lumefantrine Provided By Community Health Workers In Under-Five Children With Uncomplicated Malaria In Rural Tanzania: An Open Label Prospective Study, B.E. Ngasala, M. Malmberg, A.M. Carlsson, P.E. Ferreira, M.G. Petzold, D. Blessborn, Y. Bergqvist, J.P. Gil, Zul Premji, A. Martensson

Pathology, East Africa

Background: Home-management of malaria (HMM) strategy improves early access of anti-malarial medicines to high-risk groups in remote areas of sub-Saharan Africa. However, limited data are available on the effectiveness of using artemisinin-based combination therapy (ACT) within the HMM strategy. The aim of this study was to assess the effectiveness of artemether-lumefantrine (AL), presently the most favoured ACT in Africa, in under-five children with uncomplicated Plasmodium falciparum malaria in Tanzania, when provided by community health workers (CHWs) and administered unsupervised by parents or guardians at home.

Methods: An open label, single arm prospective study was conducted in two rural villages …

Performance Assessment Of Predicted Heat Strain In High Heat Stress, Ronald Eugene Long

USF Tampa Graduate Theses and Dissertations

Heat stress is a common physical agent associated with many occupations. The most commonly used method of assessing heat stress exposure is an empirical method using the Wet Bulb Globe Temperature Index but his method is limited in its ability to parse out individual contributors to the heat stress. The International Organization for Standardization (ISO) published a rational model called Predicted Heat Strain (PHS) in 2004, and rational methods have the advantage of separating out the individual pathways for heat exchange. The objective of this research was a performance assessment of the current PHS model. This experimental design consisted of …

A Self-Psychological Exploration Of Multiple Sclerosis In Its Biopsychosocial Context, Elisabeth Anne Parrott

Antioch University Dissertations & Theses

This theoretical dissertation constructs a new frame of reference for understanding relapsing-remitting multiple sclerosis (RRMS) using self psychology to develop a biopsychosocial formulation of the illness in order to better inform the medical treatment of patients. After conducting a critical exploration of MS in its historical context and providing a brief overview of the etiology of MS, this paper examines the phenomenology of the illness using the concepts of self psychology to further develop the theory of Engel’s (1977) biopsychosocial model. The relationship among biological, intrapsychic, and social factors and coherent conceptualization and medical treatment of multiple sclerosis is addressed. …

The Relationship Between Overweight And Obesity And Acculturation Of 12- To 19-Year-Old Mexican American Children, Elsa Ramirez-Brisson

Walden Dissertations and Doctoral Studies

Mexican Americans, one of the fastest growing segments of the population, have been identified as having above-average rates of obesity. Yet, among this group, obesity rates seem to differ by immigrant status: recent immigrants, immigrants who have lived in the United States more than 15 years, and U.S.-born Mexican Americans. Guided by the acculturation phenomenon and the social ecological model, the current study assessed all 1,732 Mexican American children 12-19 years old who participated in the National Health and Nutrition Examination Survey between 2003 and 2008 to determine the association between body mass index (BMI) and language, years living in …

A Meta-Analysis Of Cultural Competence Education In Professional Nurses And Nursing Students, Ruth Wilmer Gallagher

USF Tampa Graduate Theses and Dissertations

Cultural competence learning interventions have been suggested to positively improve knowledge, attitudes, and behaviors in both professional nurses and nursing students. A meta-analysis was used to examine the effectiveness of learning interventions designed to increase the cultural competence in professional nurses and nursing students. This is the first known meta-analysis of studies on cultural competence learning interventions in professional nurses and nursing students.

The meta-analysis was done using 13 research studies on cultural competence educational interventions from 1999 to 2010 that were published peer-reviewed literature found in electronic databases. Analyses were computed using a fixed-effect model and effect size data …

Egyptian Body Size: A Regional And Worldwide Comparison, Michelle H. Raxter

USF Tampa Graduate Theses and Dissertations

Human body size and limb proportions can provide important information about adaptation, population movements, and health disparities. This study investigated changes in body size and limb proportions of adult Egyptians temporally and geographically in relation to climatological, sociopolitical and economic developments. It was predicted that Egyptian groups that experienced more environmental stress would be shorter and exhibit less sexual dimorphism. It was also predicted that Egyptians would be intermediate between higher and lower latitude populations in body form and limb length ratios. The main skeletal sample consisted of 492 males and 528 females, all adults from the Predynastic and Dynastic …

Growing Up With Hiv: Disease Management Among Perinatally Infected Adolescents, Barbara J. Szelag

USF Tampa Graduate Theses and Dissertations

Children born with HIV in the 1980s and 1990s are surviving into adolescence and adulthood, due to the availability of highly active antiretroviral therapy (HAART). Growing up with a chronic and stigmatized disease presents considerable challenges as young people explore their sexuality, develop relationships, and take steps to become independent and productive adults. Adherence to HAART is an essential and life-long practice for the maintenance of health and longevity. For adolescents born with HIV, a daily medication schedule is one aspect of disease management that also includes medical visits, HIV status acceptance, bouts of illness, and disclosure of HIV status …

Contextualizing Hiv/Aids Prevention And Treatment Programs In Zanzibar, Tanzania, Naheed Ahmed

USF Tampa Graduate Theses and Dissertations

International aid organizations and wealthy nations have contributed billions to combat the spread and treatment of HIV/AIDS in sub-Saharan Africa; however, these programs have been critiqued for not addressing the socioeconomic and cultural context of the epidemic, instead relying upon generalized approaches. The prevalence rate in Zanzibar, Tanzania is low in the general population, but high among vulnerable segments of Zanzibari society, resulting in interventions focusing on particular groups (e.g. sex workers, drug users, and men who have sex with men). Through interviews with government agencies, non-profit organizations, medical professionals, vulnerable populations, and HIV/AIDS patients, this paper examines how local …

Adolescence Is An Ocean: A Biocultural Investigation Of Youth Food Consumption In Tanzania, Elizabeth J. Danforth

USF Tampa Graduate Theses and Dissertations

This study investigates adolescents' relationships with food and other community and household members' perceptions of youth and their food consumption to understand the multifactorial dynamic processes which create nutritional outcomes among urban and rural youth in central Tanzania. Youth are an important and demographically large population in developing countries. The identities created during this distinct stage of cultural production can be reflected in youths' food consumption and relationships with food. Nutrition likely affects how youth transition through a variety of states, including their growth and development stages, primary to secondary to higher education, child to parent, or unemployed to employed. …

The Relationship Of Race And Social Integration On The Health Status Of Older Adults In An Urban City, Thomas T. Jordan

Dissertations, Theses, and Capstone Projects

Durkheim argues that an individual is more vulnerable to self-destruction the more s/he is detached from the collective. This dissertation will explore the relative impact of social integration on older adults who have transitioned into their new roles in the social structure in relationship to their physical (obesity) and psychological (stress) health status. Additionally, the dissertation examines how social integration varies in its impact from one racial group to another, and how such variations influence the health status of the older adults who are members of these groups.

This dissertation employs data from the Brookdale Center for Healthy Aging and …

Maternal Defense: Breastfeeding Heightens Aggression By Reducing Stress, Jennifer Hahn-Holbrook, Julianne Holt-Lunstad, Colin Holbrook, Sarah M. Coyne, E. Thomas Lawson

Psychology Faculty Articles and Research

Mothers in numerous species exhibit heightened aggression in defense of their young. This shift typically coincides with the duration of lactation in nonhuman mammals, which suggests that human mothers may display similarly accentuated aggressiveness while breast feeding. Here we report the first behavioral evidence for heightened aggression in lactating humans. Breast-feeding mothers inflicted louder and longer punitive sound bursts on unduly aggressive confederates than did formula-feeding mothers or women who had never been pregnant. Maternal aggression in other mammals is thought to be facilitated by the buffering effect of lactation on stress responses. Consistent with the animal literature, our results …

African American Adolescents At Risk: Their Stories Revealed Through Dance/Movement Therapy, Alicia Marie Williams

Creative Arts Therapies Theses

The purpose ofthis study was originally to support the voices of African American adolescents and the emergence of their stories through the use of mentors hip, dance/movement therapy, and the production of an artistic performance. But what I truly found was that through parallel processing this study turned into an artistic inquiry that helped me uncover more insight about my own story: a story ofloss, isolation, rejection, recovery, independence, support and acceptance, and confidence.

As a result of the artistic inquiry I was able to see the value of my knowledge from integrating my experiences. I developed confidence in my …

The Ingredients Of Change: A Political Ecology Approach To Diabetes In The Somali Community Of Minnesota, Mina Tehrani

Geography Capstone Projects

In the early 1990’s, due to political circumstances at home, Somali immigrants and refugees began arriving in the state of Minnesota in large numbers. Over the past two decades, Somali immigrants have come to comprise one of the most populous ethnic groups in the Twin Cities, and are the largest Somali population in the world outside of Eastern Africa. Although quantitative data is unavailable, qualitative evidence and testimonies of healthcare professionals support the conclusion that Somali immigrants in Minnesota suffer from higher rates of diabetes than non-immigrant groups and than they likely did before migration. Why might this be the …

Shrouded In Stigma: A Heuristic Study Of Living With Hiv, Neal Stacy Rosenburg

Dissertations

HIV-related stigma is a serious hindrance to addressing the recruitment, maintenance, and follow-up nursing care of HIV-infected persons. This study was anchored within the heuristic research model, which engaged both the researcher and participants in a dialogical and aesthetic manner to unveil the stigma of HIV. The close proximity of the researcher and study participants revealed the most visceral, emotional, and self-reflective nature of gathering data, while maintaining the integrity and rigor of a qualitative study. The purpose of this heuristic study was to examine the lived experiences of HIV-infected individuals relating to internalized stigma within an existential context. This …

Full Issue, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Acknowledgements, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

The Multilevel, Multicultural, And Multi-Temporal Ecosocial Framework Of Population Health : How Neighborhoods, Culture, And History Impact Health Outcomes And Produce Health Disparities, Lawrence Tarves Brown

Theses and Dissertations (ETD)

According to findings in the field of genetics, it has now been established that the impact of race on health is mostly a function of a people's lived experience, not their genetic make-up. Due to this, the role of race in the study of health outcomes and health disparities has traditionally been specified improperly in statistical models due to confounding with ethnicity. Additionally, the role of geography or the impact of neighborhoods on health is often not specified properly.

Thus, the author proposes a multilevel, multicultural, and multi-temporal ecosocial framework that explains the impact of neighborhoods on health and the …

Friends Of The Library Mcnair Scholarship Awards, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Percepciones De Género En La Medicina Mapuche: Machi, Matriarca, Y Colonización, Krista Douglass

Independent Study Project (ISP) Collection

Gender is a social ordering principle; a definition of masculinity and femininity according to an individual culture. While in Chile gender identity is often shaped by machismo, the Mapuche cosmovision is without gender disparities. Rather, relationships between men and women are governed by principles of equality and duality, just as the Mapuche deities balance both male and female energies. Women hold very important roles in the community as the leaders of the medical community. Although both men and women participate in various roles within this profession, machi, the spiritual healers, are mostly women. Males, or wentru machi, …

Marshall University Joan C. Edwards School Of Medicine, Professional Enhancement Newsletter, Fall/Winter 2010, Darshana Shah

Professional Enhancement News (PEN)

Fall/Winter 2010. Volume 2, Number 2

Wilderness Beauty: A Means To Resolve Volitional Doubt, Brian T. Scalise

Liberty Theological Review

Doubt is often part of Christian spiritual life. Matured doubt will influence the will (the volition) so as to keep the Christian doubter from acting like a Christian or even desiring the Christian life. This essay seeks to construct a theory designed to engage and help resolve volitional doubt by use of wilderness beauty. This theory incorporates three areas of study—Land and Leisure Management, Abraham Maslow’s metamotivation theory, and Jonathan Edwards' aesthetic theology—to demonstrate the uniqueness and usefulness of wilderness beauty for resolving volitional doubt. Subsequent to the construction of the theory, practical suggestions for its application are given.