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In Search Of Argentinidad: Identity Affirming Bodies In Movement In Latino-America, Melissa Maldonado-Salcedo Sep 2016

In Search Of Argentinidad: Identity Affirming Bodies In Movement In Latino-America, Melissa Maldonado-Salcedo

Dissertations, Theses, and Capstone Projects

This project is a multi-sited investigation into the production of Argentinidad (the embodied feeling of Argentine national identity) post the economic crisis of 2001 known as el Argentinazo. A special attention is paid to the role of the body as a culturally and socially mediated site of identity formation. Additionally, this project engages with the intersections of cultural and psychoanalytic theories that have influenced Argentinean self-identity in addition to social identities that are negotiated in moments of personal and national crisis. This project examines the roles and relationships of family and migration within Argentinean diasporic communities originating from the Provinces …


Eakles, Elaine (Fa 902), Manuscripts & Folklife Archives Sep 2016

Eakles, Elaine (Fa 902), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid only for Folklife Archives Project 902. Project titled: “Folk Remedies and Cures From Plants.” Project includes note cards of folk medicine beliefs from the Penny Royal Region in Kentucky. Note cards include a brief description, informant’s name, and the motif index number.


Caswell, Galena (Fa 900), Manuscripts & Folklife Archives Sep 2016

Caswell, Galena (Fa 900), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid only for Folklife Archives Project 900. Project titled: “[Folk remedies]” Project includes survey sheets with brief descriptions of folk remedies of the Penny Royal region in Kentucky. Note cards include a brief description, informant’s name, and motif reference.


Tusker Power: Informal Science Education At The State Museum, Sarah Feit Sep 2016

Tusker Power: Informal Science Education At The State Museum, Sarah Feit

SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016

Museum Mission:

Research Divisions – University of Nebraska

Ashfall Fossil Beds State Historical Park

Trailside Museum of Natural History

Morrill Hall

Mueller Planetarium in Morrill Hall

Accreditation and Affiliation

Sunday with a Scientist

Investigate: Second Saturday Science Lab

Science Café

Museum NU – Virtual Field Trips

Portal to the Public Network


Commentaries On Deepak Chopra And Menas Kafatos’ Book, “You Are The Universe”; 2017, Harmony Books., Jim Smith Sep 2016

Commentaries On Deepak Chopra And Menas Kafatos’ Book, “You Are The Universe”; 2017, Harmony Books., Jim Smith

CONSCIOUSNESS: Ideas and Research for the Twenty-First Century

No abstract provided.


Why Consciousness Matters: Insights From A New Generation, Kathleen Noble Sep 2016

Why Consciousness Matters: Insights From A New Generation, Kathleen Noble

CONSCIOUSNESS: Ideas and Research for the Twenty-First Century

The University of Washington-Bothell is home to a transdisciplinary and integral minor in consciousness that is the first and only such program at a public research university. This study reports a content analysis of reflection essays submitted by 122 students who completed at least four of the five courses that comprise the minor between 2012 and 2016. Results indicate that students derived significant benefits from this approach to the study of consciousness, including a deep appreciation for the depth and breadth of the mind and the need to release their understanding of consciousness from the constraints of scientific materialism. They …


Foster, Gary (Fa 885), Manuscripts & Folklife Archives Sep 2016

Foster, Gary (Fa 885), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid only for Folklife Archives Project 885. Paper titled: “Folk Cures of Barren County.” Project includes index cards with brief descriptions of folk cures along with a map of the collection area in Barren County, Kentucky. Cards include a brief description of the cure and informant’s name.


Temporal And Spatial Distribution Of Enterobius Vermicularis (Nematoda: Oxyuridae) In The Prehistoric Americas, Karl J. Reinhard, Adauto Araújo, Johnica J. Morrow Sep 2016

Temporal And Spatial Distribution Of Enterobius Vermicularis (Nematoda: Oxyuridae) In The Prehistoric Americas, Karl J. Reinhard, Adauto Araújo, Johnica J. Morrow

Karl Reinhard Publications

Investigations of Enterobius sp. infection in prehistory have produced a body of data that can be used to evaluate the geographic distribution of infection through time in the Americas. Regional variations in prevalence are evident. In North America, 119 pinworm positive samples were found in 1,112 samples from 28 sites with a prevalence of 10.7%. Almost all of the positive samples came from agricultural sites. From Brazil, 0 pinworm positive samples were found in 325 samples from 7 sites. For the Andes region, 22 pinworm positive samples were found in 411 samples from 26 sites for a prevalence of 5.3%. …


Empty Metal Jacket: The Biopolitical Economy Of War And Medicine, Sandra Lee Trappen Sep 2016

Empty Metal Jacket: The Biopolitical Economy Of War And Medicine, Sandra Lee Trappen

Dissertations, Theses, and Capstone Projects

Empty Metal Jacket: The Biopolitical Economy of War and Medicine undertakes study of how global conflict and violence shape the entire range of social production, from commodities and culture to social goods and social theory. The research presented in this work draws from cutting-edge theories in body and science studies, in addition to theories of affect and biopolitics to address how war became a problem solving paradigm in medicine. Combat casualties are shown to serve as a material nexus for medical knowledge production. Although the focus here is on medicine and medical innovation in particular, these developments are connected to …


Research Highlights (July-September 2016), Reteka Sexena Sep 2016

Research Highlights (July-September 2016), Reteka Sexena

Indian Journal of Research in Homoeopathy

No abstract provided.


Cleaning Puparia For Forensic Analysis, Leon G. Higley, Tierney R. Brosius, Karl Reinhard, David Carter Sep 2016

Cleaning Puparia For Forensic Analysis, Leon G. Higley, Tierney R. Brosius, Karl Reinhard, David Carter

Karl Reinhard Publications

We tested procedures for removing adipocere from insect samples to allow identification. An acceptable procedure was determined: (i) Samples were sorted in petri dishes with 75% alcohol to remove any larvae, adult insects, or other soft-bodied material. (ii) Samples of up to 24 puparia were placed in a vial with 15 mL of 95% acetone, capped, and vortexed for a total of 30–90 sec in 10- to 15-sec bursts. This step removed large masses of adipocere or soil from specimen. (iii) Specimens were removed from acetone and placed in a vial of 15 mL of 2% potassium hydroxide (KOH) and …


Variation Of Driving Skill Among Elderly Drivers Compared To Young Drivers In Japan, Indri Hapsari Susilowati, Akira Yasukouchi Aug 2016

Variation Of Driving Skill Among Elderly Drivers Compared To Young Drivers In Japan, Indri Hapsari Susilowati, Akira Yasukouchi

Kesmas

Penelitian ini menganalisis kemampuan mengemudi pada pengemudi lanjut usia (lansia) dibandingkan dengan usia muda di Jepang dan melihat keterampilan mengemudi yang kurang sehingga dapat memengaruhi risiko kecelakaan di jalan raya. Subjek penelitian adalah pengemudi usia muda dan lansia, terdiri dari 10 mahasiswa (20 - 24 tahun) dan 25 pengemudi lansia (14 laki-laki dan 11 perempuan) berasal dari The Silver Menpower Center, organisasi bagi lansia > 60 tahun. Pengemudi lansia dibagi menjadi dua kelompok, yaitu lansia 1 berusia 60 - 65 tahun (10 orang) dan lansia 2 berusia > 65 tahun (15 orang). Kemampuan mengemudi dievaluasi dengan simulator permainan mengemudi dalam laboratorium. Analisis …


Interprofessional Research, Training And Outreach: The Etsu Prescription Drug Abuse/Misuse Working Group, Robert P. Pack, Angela Hagaman, Sara Warfield, Jeffry A. Gray, Fred Tudiver, Arsham Alamian, Nicholas E. Hagemeier Aug 2016

Interprofessional Research, Training And Outreach: The Etsu Prescription Drug Abuse/Misuse Working Group, Robert P. Pack, Angela Hagaman, Sara Warfield, Jeffry A. Gray, Fred Tudiver, Arsham Alamian, Nicholas E. Hagemeier

International Journal of Health Sciences Education

No abstract provided.


Who Solves Your Most Urgent Medical Questions?, Darren Stoub Aug 2016

Who Solves Your Most Urgent Medical Questions?, Darren Stoub

Faculty Work Comprehensive List

"If such specialized training is necessary to become a physician, why do we think that a 10-minute web search will provide an answer to our medical problems?"

Posting about reliable sources of medical information from In All Things - an online hub committed to the claim that the life, death, and resurrection of Jesus Christ has implications for the entire world.

http://inallthings.org/who-solves-your-most-urgent-medical-questions/


The Juvenile Addiction Risk Rating For Use In Vocational Rehabilitation, Paul Tyler Hickerson Aug 2016

The Juvenile Addiction Risk Rating For Use In Vocational Rehabilitation, Paul Tyler Hickerson

Graduate Theses and Dissertations

The prevalence of substance use among adolescents warrants considerable concern since it often has detrimental effects on an individual’s physical and mental health, and correlates with worsened Social, physical, and employment outcomes. Research shows that adolescents with disabilities are especially susceptible to the development of substance use disorders. To address this concern and to ensure accurate rehabilitation service planning, effective screening for substance use risk is necessary. Unfortunately, the most common screening instruments for adolescent substance use rely on information obtained solely from self-report. This type of data, although useful, is also susceptible to inaccuracies due to such factors as …


Treatment Recidivism In Adolescents With Mental Illness: A Focused Applied Medical Ethnography, Chukwudi C. Ekwemalor Aug 2016

Treatment Recidivism In Adolescents With Mental Illness: A Focused Applied Medical Ethnography, Chukwudi C. Ekwemalor

Dissertations and Theses (Open Access)

Background

Treatment recidivism, described as frequent unplanned relapse readmissions, is a national problem predominant in adolescents with mental illness with significant socioeconomic consequences. Adolescents living with mental illness are a sub-culture of adolescence, the critical growth period of developmental and social transition from childhood to adulthood. The main triggers of treatment recidivism in this population are not fully understood from previous studies.

Purpose

The study purpose was to explore treatment recidivism with the following aims:

1. To illuminate treatment recidivism from the perspectives of recidivist adolescents with mental illness.

2. To describe the main factors that contribute to treatment recidivism …


Effects Of Human Maternal Placentophagy On Postpartum Maternal Affect, Health, And Recovery, Sharon Marie Young Aug 2016

Effects Of Human Maternal Placentophagy On Postpartum Maternal Affect, Health, And Recovery, Sharon Marie Young

UNLV Theses, Dissertations, Professional Papers, and Capstones

Postpartum ingestion of the afterbirth by the mother, or maternal placentophagy, is a common behavior among eutherian mammals, including non-human primates, with humans as a rare exception. Despite the conspicuous absence of placentophagy in the cross-cultural ethnographic record, the practice appears to be gaining popularity among a small but growing number of advocates in various industrialized contexts who claim that the practice provides benefits to the postpartum mother, namely the relief and prevention of postpartum blues and depressive symptoms, improved breast milk production, and enhanced bonding with their infant. Because the placenta serves as an endocrine organ throughout pregnancy and …


To Foster A Culture Of Curiosity: A Hermeneutic Study Of The Experienced Nurse Educator And Student Intellectual Curiosity In The Online Learning Environment, Bedelia H. Russell Aug 2016

To Foster A Culture Of Curiosity: A Hermeneutic Study Of The Experienced Nurse Educator And Student Intellectual Curiosity In The Online Learning Environment, Bedelia H. Russell

Electronic Theses and Dissertations

Skills of inquiry are essential outcomes from a baccalaureate nursing education. Students who demonstrate intellectual curiosity can develop effective skills of inquiry. Nurse educators must place emphasis on teaching and learning strategies which engage student intellectual curiosity. However, the concept of intellectual curiosity is not well-studied across multiple contexts of teaching and learning environments within nursing education. In addition, there is little known about the experienced nurse educator and the meaning of student intellectual curiosity across multiple teaching and learning environments. With the increased emphasis on online teaching and learning in nursing education as a solution for expanding student access …


Cryptosporidium Parvum Among Coprolites From La Cueva De Los Muertos Chiquitos (600–800 Ce), Rio Zape Valley, Durango, Mexico, Johnica J. Morrow, Karl Reinhard Aug 2016

Cryptosporidium Parvum Among Coprolites From La Cueva De Los Muertos Chiquitos (600–800 Ce), Rio Zape Valley, Durango, Mexico, Johnica J. Morrow, Karl Reinhard

Karl Reinhard Publications

In the present study, 90 coprolites from La Cueva de los Muertos Chiquitos (CMC) were subjected to enzyme-linked immunosorbent assay (ELISA) tests for 3 diarrhea-inducing protozoan parasites, Entamoeba histolytica, Giardia duodenalis, and Cryptosporidium parvum, to determine whether these parasites were present among the people who utilized this cave 1,200–1,400 yr ago. These people, the Loma San Gabriel, developed as a culture out of the Archaic Los Caracoles population and lived throughout much of present-day Durango and Zacatecas in Mexico. The Loma San Gabriel persisted through a mixed subsistence strategy of hunting-gathering and agricultural production. The results of …


Association Between Alcohol Screening And Brief Intervention During Routine Check-Ups And Alcohol Consumption Among Adults Living In California, Gene Kilian Wells Aug 2016

Association Between Alcohol Screening And Brief Intervention During Routine Check-Ups And Alcohol Consumption Among Adults Living In California, Gene Kilian Wells

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: Alcohol consumption accounts for 1 in 10 deaths among U.S. adults, and has cost upwards of $200 billion in a single year due to lost productivity. Alcohol Screening and Brief Intervention (ASBI) was developed as a treatment approach for use in primary care to identify and reduce hazardous and harmful substance use behaviors among the general population. Although ASBI has proven to be successful, implementation rates remain low. Few studies have been conducted in Nevada to encourage or improve ASBI implementation in primary care. In order to better support Nevada policy decisions, this study investigates the proportion of ASBI …


Access And Barriers To Services For Dependent And Non-Dependent Commercially Sexually Exploited Children In Florida, Brianna O'Steen Jul 2016

Access And Barriers To Services For Dependent And Non-Dependent Commercially Sexually Exploited Children In Florida, Brianna O'Steen

USF Tampa Graduate Theses and Dissertations

“Human trafficking” has become part of the everyday lexicon in the United States and globally over the last fifteen years. The issue has made its way into political platforms, scholarly work, church congregations, and international aid agendas. Florida is currently recognized as third in the nation for number of cases of human trafficking. This thesis employs ethnographic interviews and observations to understand one portion of Florida’s human trafficking problem referred to as domestic minor sex trafficking. This type of trafficking affects mostly teenage girls from marginalized populations, such as those that have experienced the child welfare system, homelessness, and impoverished …


The Integration Of Quantitative Genetics, Paleontology, And Neontology Reveals Genetic Underpinnings Of Primate Dental Evolution, Leslea J. Hlusko, Christopher A. Schmitt, Tesla A. Monson, Marianne F. Brasil, Michael Mahaney Jul 2016

The Integration Of Quantitative Genetics, Paleontology, And Neontology Reveals Genetic Underpinnings Of Primate Dental Evolution, Leslea J. Hlusko, Christopher A. Schmitt, Tesla A. Monson, Marianne F. Brasil, Michael Mahaney

School of Medicine Publications

Significance

Experimental research on mice has yielded tremendous biological insight. However, the ∼140 million y of evolution that separate mice from humans pose a hurdle to direct application of this knowledge to humans. We report here that considerable progress for identifying genetically patterned skeletal phenotypes beyond the mouse model is possible through transdisciplinary approaches that include the anatomical sciences. Indeed, anatomy and paleontology offer unique opportunities through which to develop and test hypotheses about the underlying genetic mechanisms of the skeleton for taxa that are not well suited to experimental manipulation, such as ourselves.

Abstract

Developmental genetics research on mice …


Intersecting Positions Of Social Disadvantage And Self-Reported Health Status Disparities, Carla S. Alvarado, Chunhuei Chi Jul 2016

Intersecting Positions Of Social Disadvantage And Self-Reported Health Status Disparities, Carla S. Alvarado, Chunhuei Chi

Journal of Health Disparities Research and Practice

Health disparities along the gender, race and class are particularly important to monitor and study given the predicted differential distribution of health along these social identities. Intersectionality is a theoretical framework that allows public health and health disparities researchers to account for the simultaneous, mutually constitutive, reinforcing and multidimensional effects of gender, class, and race with the aim to better understand health disparities. Disparities along gender, race and class have been noted in self-reported health status (SRHS) which has been shown to be a strong predictive factor of mortality, morbidity and mental health independent of other physiologic, behavioral and psychosocial …


Digital Storytelling As Poetic Reflection In Occupational Therapy Education: An Empirical Study, Lisebet S. Skarpaas, Grete Jamissen, Cecilie Krüger, Vigdis Holmberg, Pip Hardy Jul 2016

Digital Storytelling As Poetic Reflection In Occupational Therapy Education: An Empirical Study, Lisebet S. Skarpaas, Grete Jamissen, Cecilie Krüger, Vigdis Holmberg, Pip Hardy

The Open Journal of Occupational Therapy

Stories are powerful aids to reflection. Thus, the use of stories may be a pathway to enhanced reflective practice and clinical reasoning skills. The aim of this study was to evaluate whether and how digital storytelling can contribute to occupational therapy (OT) students’ learning through reflections on experiences from placement education. A cohort of OT students (n = 57) participated in a 2-day workshop to create digital stories. Data were generated through a questionnaire with a response rate of 100% of students who completed the workshop (n = 34). Quantitative analysis methods were used to reveal a level of agreement …


Developing An Indigenous, Entry-Level Master’S Degree Program In A Country With An Emerging Ot Profession, Lesley A. Garcia, Julie D. Kugel, Heather Javaherian-Dysinger, Esther Huecker Jul 2016

Developing An Indigenous, Entry-Level Master’S Degree Program In A Country With An Emerging Ot Profession, Lesley A. Garcia, Julie D. Kugel, Heather Javaherian-Dysinger, Esther Huecker

The Open Journal of Occupational Therapy

In the Republic of Trinidad and Tobago the full range of physical, mental, psychological, and socially derived problems of occupational engagement exist. Occupational therapy is often a part of the health care team to address these challenges; however, the profession is at an emergent stage in the country. This paper describes a process used for the development of an indigenous entry-level master’s degree program in occupational therapy. The process was also supported and enhanced by the collaborative relationships among key stakeholders, including global partners. A qualitative design process was used to analyze the health care needs, barriers, and strategies that …


Stretching The Boundaries Of Medical Education: A Case Of Medical College Embracing Humanities And Social Sciences In Medical Education, Kulsoom Ghias, Kausar S. Khan, Rukhsana Ali, Shireen Azfar, Rashida Ahmed Jul 2016

Stretching The Boundaries Of Medical Education: A Case Of Medical College Embracing Humanities And Social Sciences In Medical Education, Kulsoom Ghias, Kausar S. Khan, Rukhsana Ali, Shireen Azfar, Rashida Ahmed

Community Health Sciences

Objective:

Aga Khan University, a private medical college, had a vision of producing physicians who are not only scientifically competent, but also socially sensitive, the latter by exposure of medical students to a broad-based curriculum. The objective of this study was to identify the genesis of broad-based education and its integration into the undergraduate medical education program as the Humanities and Social Sciences (HASS) course.

Methods:

A qualitative methodology was used for this study. Sources of data included document review and in-depth key informant interviews. Nvivo software was utilized to extract themes.

Results:

The study revealed the process of operationalization …


Evasions In Interactions: Examples From The Transcultural Nursing Research Field, Janice D. Crist Phd, Rn, Fngna, Faan, Heather Coats Ms, Aprn-Bc, Phd, Kay Lehman Rn, Msn, Cwocn, Isela Luna Rn, Phd, Ccm Jun 2016

Evasions In Interactions: Examples From The Transcultural Nursing Research Field, Janice D. Crist Phd, Rn, Fngna, Faan, Heather Coats Ms, Aprn-Bc, Phd, Kay Lehman Rn, Msn, Cwocn, Isela Luna Rn, Phd, Ccm

The Qualitative Report

Transcultural qualitative research is known for its utility in eliciting in-depth narratives, resulting in increased understanding about cultural phenomena. However, sometimes specific phenomena in the researcher’s inquiry are ignored, evaded, or denied; or a seemingly crucial experience demonstrating society’s unfairness, which the researcher had been expecting, does not emerge. In this paper, the issue of evasions in narratives is addressed, with two examples in which participants evaded the issue about which they were asked: perceptions of discrimination for aging adults of Mexican descent, and perceptions of living with life-limiting illnesses for aging African American adults. The Ethno-Cultural Gerontological Nursing Model …


Understanding Reproductive Health Among Burmese Refugees In Greeley, Colorado: An Ethnographic Account, Alexandra Julia Krumtum Jun 2016

Understanding Reproductive Health Among Burmese Refugees In Greeley, Colorado: An Ethnographic Account, Alexandra Julia Krumtum

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

In the past four years, over 1,000 Burmese refugees have settled in Greeley, Colorado, but little is known about their conceptualizations of health or their experiences with local medical institutions. This paper investigates Burmese refugee women’s reproductive health beliefs and interactions with biomedical professionals. Through ethnographic interviews and participant observation, I show that a lack of mutual understanding between the two groups contributes to issues in communication and difficulties in promoting medical care. Medical anthropological research shows that culture has important implications for the experience and outcome of illness, as well as for the utilization of medical services and likelihood …


“A Wound That Never Heals”: Health-Seeking Behaviors And Attitudes Towards Breast Cancer And Cancer In General Among Women In Nakirebe, Uganda, Ann Louise Tezak Jun 2016

“A Wound That Never Heals”: Health-Seeking Behaviors And Attitudes Towards Breast Cancer And Cancer In General Among Women In Nakirebe, Uganda, Ann Louise Tezak

USF Tampa Graduate Theses and Dissertations

The scale and severity of cancer, specifically breast cancer, remains significantly different across the spectrum of low-income to high-income countries. This study explores women’s beliefs about breast cancer and associated prevention and health-seeking behaviors in a rural area of Uganda. Through a critical medical anthropological perspective, the study examines the social, cultural, and economic factors that shape women’s understanding of cancer, and breast cancer specifically, and that influence their use of biomedical services. Data were collected over a three-month period through 35 in-depth interviews and two focus groups with 10 women older than 18 years in the rural setting of …


Female Chromosome X Mosaicism Is Age-Related And Preferentially Affects The Inactivated X Chromosome, Mitchell J. Machiela, Weiyin Zhou, Eric Karlins, Joshua N. Sampson, Neal D. Freedman, Qi Yang, Belynda Hicks, Casey Dagnall, Christopher Hautman, Kevin B. Jacobs, Christian C. Abnet, Melinda C. Aldrich, Christopher Amos, Laufey T. Amundadottir, Alan A. Arslan, Laura E. Beane-Freeman, Sonja I. Berndt, Amanda Black, William J. Blot, Cathryn H. Bock, Paige M. Bracci, Louise A. Brinton, H Bas Bueno-De-Mesquita, Laurie Burdett, Julie E. Buring, Mary A. Butler, Federico Canzian, Tania Carreon, Kari G. Chaffee, I-Shou Chang, Nilanjan Chatterjee, Chu Chen, Constance Chen, Kexin Chen, Charles C. Chung, Linda S. Cook, Marta Crous Bou, Michael Cullen, Faith G. Davis, Immaculata De Vivo, Ti Ding, Jennifer Doherty Jun 2016

Female Chromosome X Mosaicism Is Age-Related And Preferentially Affects The Inactivated X Chromosome, Mitchell J. Machiela, Weiyin Zhou, Eric Karlins, Joshua N. Sampson, Neal D. Freedman, Qi Yang, Belynda Hicks, Casey Dagnall, Christopher Hautman, Kevin B. Jacobs, Christian C. Abnet, Melinda C. Aldrich, Christopher Amos, Laufey T. Amundadottir, Alan A. Arslan, Laura E. Beane-Freeman, Sonja I. Berndt, Amanda Black, William J. Blot, Cathryn H. Bock, Paige M. Bracci, Louise A. Brinton, H Bas Bueno-De-Mesquita, Laurie Burdett, Julie E. Buring, Mary A. Butler, Federico Canzian, Tania Carreon, Kari G. Chaffee, I-Shou Chang, Nilanjan Chatterjee, Chu Chen, Constance Chen, Kexin Chen, Charles C. Chung, Linda S. Cook, Marta Crous Bou, Michael Cullen, Faith G. Davis, Immaculata De Vivo, Ti Ding, Jennifer Doherty

Dartmouth Scholarship

To investigate large structural clonal mosaicism of chromosome X, we analysed the SNP microarray intensity data of 38,303 women from cancer genome-wide association studies (20,878 cases and 17,425 controls) and detected 124 mosaic X events 4 2 Mb in 97 (0.25%) women. Here we show rates for X-chromosome mosaicism are four times higher than mean autosomal rates; X mosaic events more often include the entire chromosome and participants with X events more likely harbour autosomal mosaic events. X mosaicism frequency increases with age (0.11% in 50-year olds; 0.45% in 75-year olds), as reported for Y and autosomes. Methylation array analyses …